Oral Oncology Extra最新文献

Lung cancer is the most frequently encountered cancer in humans and commonly metastasizes to brain and bone. A case is presented of a 65-year-old man with squamous cell carcinoma of the lung that metastasised to the temporomandibular joint (TMJ). The case is unusual in many respects. The TMJ was displaced and destructed by the tumor and it was the initial manifestation of squamous lung cancer.

A rare case of chondrosarcoma of the mandibular symphyseal region in a 39-year-old man is presented. The patient complained of a recurring and growing mass on the labial side of the mandibular gingiva extending from the right lateral incisor to the left canine. Radiographs showed irregularly shaped osteoblastic lesion with radiopacity corresponding to the mass. MR images showed the lesion to be well-defined and adjacent to the labial cortex without bone marrow invasion. The mass was histologically diagnosed as grade 2 chondrosarcoma. Nineteen months after marginal resection with tumour-free margins, there was no evidence of recurrence or metastasis.

Deep lobe of the parotid gland is a rare localisation of head and neck tumors and most of them are pleomorphic adenoma. We encountered a 76-year-old woman with deep lobe parotid gland oncocytic neoplasms (synchronous oncocytoma and multifocal nodular oncocytic hyperplasia), but without any complaints. The patient was operated for larynx carcinoma four years ago. A deep lobe parotid gland lesion was detected during radiological evaluation of her middle ear cholesteatoma. A near total parotidectomy was performed. Oncocytoma is an uncommon salivary gland tumor and generally occurs in the superficial lobe of parotid gland of older patients. Multifocal nodular oncocytic hyperplasia is an unusual parotid gland lesion that accounts for 0.1% of parotid tumors. Computed tomography, magnetic resonance imaging, FNA and sialoscintigraphy may be helpful for evaluating parotid gland oncocytomas. Acinic cell carcinoma and clear cell carcinoma were the main differential diagnosis of oncocytoma. Surgical removal is the treatment of choice and total parotidectomy is suggested for deep lobe parotid gland oncocytomas. Recurrences are unusual for oncocytoma. Long-term follow up is necessary for multinodular cases. Parotid gland space occupying lesions may necessitate further emphasis regarding the fact that either second primary or a metastatic lesion may be found in especially a previously noted head and neck carcinoma patient.

Angiomyolipoma of the oral cavity is an extremely rare benign hamartomatous tumour that occurs separately, unrelated to other conditions. As the name implies, the microscopic features comprise of mature adipose tissue, thick walled blood vessels, and smooth muscle cells which stain positive for smooth muscle actin. Our case involved a 54 year-old female who presented with a long-standing, slow growing, and asymptomatic mass on the palate. Medical history revealed no contributory factors to her condition, and the lesion doubled in size in a 12 month period. Surgical excision is the treatment of choice for this entity.

The adenoid pattern seen in Basaloid squamous carcinoma (BSC) and adenoid cystic carcinoma (ACC) of head neck region may form a major portion in biopsies and pose diagnostic difficulties. In the present case histology of tongue swelling revealed an adenoid pattern with squamous differentiation and keratin pearls in some of these adenoid spaces. The overlying mucosa showed an in situ squamous carcinoma. Immunohistochemical (IHC) stains showed CK and EMA positivity in squamous and adenoid areas, CEA was positive only in squamous areas while Vimentin and S100 protein were negative. These IHC stains thus helped in the distinction of BSC from ACC as ACC is clinically less aggressive.

The odontogenic keratocyst (OKC) is well known for its tendency to recur, potential aggressive behaviour and defined histopathological feature. OKC occurrence in the maxilla is unusual and its appearance in the maxillary sinus very uncommon. This article reports two distinct cases of OKCs associated with unerupted molars in the maxillary sinus of two boys. The lesions were surgically treated and no recurrence has been observed on follow-up. OKC clinical features and treatment are discussed.

Angioleiomyoma in the mouth is described as a rare symptomless, slowly growing mass, most commonly presenting on the lip. Here we present a case of angioleiomyoma on the hard palate with atypical symptoms of pain and fluctuation in size.

The clinical, histopathological, immunohistochemical and histochemical features of an alveolar soft part sarcoma involving dorsum surface of the tongue of a 17-year-old girl are described. This is a rare tumour of uncertain histogenesis. There has been no evidence of recurrence or metastasis after one year of follow-up.

A 72 year-old male, seven years later the first diagnosis of rectal adenocarcinoma, referred a trouble in hard palate. Clinical examination evidenced a whitish coloured projecting area, not painful at palpation and with the largest diameter of 2 cm. The first biopsy suggested a neoplastic lesion but it was not resolutive for diagnosis. Another biopsy was executed. The second histological report evidenced a neoplastic infiltration of poorly differentiated adenocarcinoma, with mucinous aspects and necrosis. Immunophenotype was compatible with diagnosis of metastasis of adenocarcinoma originated from large bowel. The pathological diagnosis was confirmed by a second pathologist.

The case of an intraosseous leiomyoma in a 57-year-old man is presented. The tumor was incidentally discovered during routine dental X-ray examination as a round, unilocular, radiolucency, measuring approximately 2 × 1.5 cm. Clinical examination revealed a slight swelling of the buccal cortical plate in the edentulous area of the posterior right mandible, and intra-operatively, perforation of the buccal cortical plate was seen. Histological and immunohistochemical examination was diagnostic of solid leiomyoma. One year after surgery the patient is free of residual or recurrent disease. This is the fifteen documented cases of intraosseous leiomyoma reported in the English literature.