Oral Oncology Extra最新文献

Extra skeletal Ewing’s sarcoma (EES) is rare. EES commonly arises in the soft tissues of trunk or extremities. EES is rare in the region of head and neck; most of those have been documented in nasal cavity, para nasal sinuses and neck. Prognosis and survival statistics have been poor. Our patient was diagnosed to have PNET of thyroid who presented to us with distant metastases after prior surgery and succumbed after 1st cycle of anthracycline-based chemotherapy.

Myeloid sarcoma is a tumour mass of myeloblasts or immature myeloid cells occurring in an extra-medullary site or in a bone. The tumour may precede or occur concurrently with acute or chronic myeloid leukaemia or with other types of myeloproliferative disorders or myelodysplastic syndromes. Granulocytic sarcoma is a rare presentation in the oral and maxillofacial region, but has been reported in oral soft tissues as well as in intra-osseous sites. The majority of these cases occur in patients with known leukaemia or those who eventually develop the disease. Our report details the presentation of myeloid sarcoma in radicular cyst capsule, being also one of the unusual intra-osseous presentations of this rare tumour.

The ameloblastic fibro-odontoma (AFO) is defined as a tumour with the general features of ameloblastic fibroma but that also contains enamel and dentin. AFO normally presents as a painless swelling in the posterior portion of the maxilla or mandible. Radiographs show a well-defined radiolucent area containing various amounts of radiopaque material of irregular size and form. This article reports a case of AFO affecting a 14-year-old boy. As a radiographic exam performed five years previously was available, the development of the lesion over this period is described. The lesion was surgically treated. No recurrence has been observed on follow-up.

Adult rhabdomyoma (AR) is a rare benign tumor of the skeletal muscle that usually occurs in the head and neck region. AR present in a mean age of 50 years and occur commonly in males than females (4:1). Treatment is excision and recurrence is rare. The aim of this paper is to describe the clinicopathologic features of an AR and its differential diagnosis to avoid unnecessary aggressive treatment and present the fifth AR occurred in a child.

Malignant peripheral nerve sheath tumour (MPNST) is a rare malignant neoplasm in the maxillofacial region. This study reports on a sporadic case of MPNST located on the tongue and provides a review of existing literature regarding this lesion. Data analyses show four well-documented cases of MPNST on the tongue.

This case series describes three unreported cases of an uncommon benign neoplasm named Abrikossoff’s tumour or granular cell tumour (GCT). This mesenchymal neoplasm apparently arises from neural or Schwann cell origin with benign and malignant forms. All cases presented here were unique nodules on oral mucosa, coming out from the connective tissue, and occurring in women with age ranging from 30 to 42 years. The histological aspects of the GCT showed large granular cells arranged in groups and nests of connective tissue separating pseudoepitheliomatous overlying surface. This feature can possibly be misunderstood with squamous cell carcinoma. The differentiation between malignant and benign GCT is evaluated by the presence of metastases which is considered the only reliable criterion for malignancy.

Primary non-Hodgkin’s lymphoma (NHL) is rare. When it does occur, mandibular NHL typically manifests similar to an odontogenic process. This results in delayed diagnosis and treatment. We present a 53-year-old male who was erroneously treated for a dental process for several months before the correct diagnosis of diffuse large B-cell lymphoma was made. Fortunately, the solitary bony lymphoma had not disseminated and management by chemo-radiation allowed for disease eradication and new, post-treatment, bone formation. The purpose of this report is to describe a rare case of NHL of the mandible, explore the diagnosis and workup, and discuss treatment strategies.

This article describes the importance of proper intraoral surgical management of an HIV positive patient who had previously received radiation therapy for the treatment of squamous cell carcinoma (SCCA). The report discusses the risk of developing osteoradionecrosis (ORN) following radiation therapy, additional oral complications and dental management documenting the need for the oral health care provider to understand these sequelae in order to best treat HIV positive patients post radiation therapy.

Kuttner tumor (KT) was first described in 1896 by Kuttner. It occurs mainly in the submandibular gland and usually presents as a firm and painful swelling. An important aspect of KT is its clinical resemblance to a salivary gland neoplasm. Histologically, the disease is characterized by progressive periductal sclerosis, acinar atrophy, and gland infiltration by lymphocytes. However, for a reliable diagnosis of KT an immunohistochemical analysis of lymphocyte subtypes is required. We report a case of KT that involved minor salivary glands of a patient that was undergoing radiotherapy in the head and neck region.

The condition with recurrence of ameloblastoma in autogenous iliac bone grafts is very rare. This report presents such a case from a 55-year-old female.