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Efficacy of traceless double-fold eyelid surgery for the treatment of upper eyelid entropion 无迹双眼皮手术治疗上睑内翻的疗效观察
Pub Date : 2019-12-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.12.008
Linxiang Zhang
Objective To evaluate the efficacy of traceless double-fold eyelid surgery combined with partial tarsectomy for the treatment of upper eyelid entropion. Methods Eighty-one eyes of 56 patients with upper eyelid entropion were treated with traceless double-fold eyelid surgery combined with partial tarsectomy from Nov.2015 to Mar.2019 in this hospital.The surgery efficacy were observed. Results The postoperative satisfactory rate was 88.89%(72/81), the good rate was 8.64%(7/81), and the general rate was 2.47%(2/81). Conclusion Traceless double-fold eyelid surgery combined with partial tarsectomy can not only play a therapeutic role, but also achieve the efficacy of double-fold eyelid beauty.This therapy is suitable for upper eyelid entropion, especially for the patient with moderate to severe meibomian hypertrophic upper eyelid entropion. Key words: Entropion, upper eyelid; Surgery, double-fold eyelid; Tarsectomy
目的探讨无迹双眼皮手术联合部分截骨术治疗上睑内翻的疗效。方法2015年11月至2019年3月对56例81眼上睑内翻患者行无迹双眼皮手术联合部分截骨术治疗。观察手术效果。结果术后满意率为88.89%(72/81),优良率为8.64%(7/81),一般率为2.47%(2/81)。结论无痕双眼皮手术联合部分跗骨切除术既能起到治疗作用,又能达到双眼皮美容的效果。此法适用于上睑内翻,尤其适用于中度至重度睑板肥厚性上睑内翻患者。关键词:内翻;上睑;手术,双眼皮;跗骨切除术
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引用次数: 0
Vitrectomy combined with internal limiting membrane peeling and posterior scleral reinforcement for macular hole of degenerative myopia 玻璃体切除术联合内限制膜剥离和后巩膜加固治疗退行性近视黄斑裂孔
Pub Date : 2019-12-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.12.009
Zhan-sheng Shen, Meng-ping Chen, Yuanyuan Li
Objective To evaluate the efficacy of vitrectomy combined with internal limiting membrane peeling and posterior scleral reinforcement for the treatment of macular hole of degenerative myopia. Methods A retrospective case study. The clinical data of 53 eyes of 53 cases of degenerative myopia with macular hole were treated with vitrectomy combined with internal limiting membrane peeling and posterior scleral reinforcement From Feb. 2014 to Aug. 2016 in this hospital were analyzed. Results BCVA (Log MAR) was 0.78±0.23 before operation and 0.62±0.19 after operation (P=0.021). Preoperative axial length was (29.52±4.67) mm, and the postoperative length shortened to (27.91±3.87) mm (P=0.041). The preoperative mean refractive status was (-17.50±-3.65) D, and the postoperative status was decreased to (-14.20±-2.84) D (P=0.004). The closure rate of macular hole was 90.6% (48/53). No serious complication such as iatrogenic tear, intraocular hemorrhage or endophthalmitis occurred. Conclusion Vitrectomy combined with internal limiting membrane peeling and posterior scleral reinforcement is safe and effective in the treatment of macular hole of degenerative myopia. Key words: Myopia, degenerative; Hole, macular; Vitrectomy; Reinforcement, posterior scleral; Peeling, membrane, limiting, internal
目的评价玻璃体切除术联合内限定膜剥离和后巩膜加固治疗退行性近视黄斑裂孔的疗效。方法回顾性病例研究。分析本院2014年2月至2016年8月对53例退行性近视伴黄斑孔53眼行玻璃体切除联合内限制膜剥离及后巩膜加固术的临床资料。结果BCVA (Log MAR)术前为0.78±0.23,术后为0.62±0.19 (P=0.021)。术前轴向长度为(29.52±4.67)mm,术后缩短为(27.91±3.87)mm (P=0.041)。术前平均屈光状态为(-17.50±-3.65)D,术后平均屈光状态为(-14.20±-2.84)D (P=0.004)。黄斑孔闭合率为90.6%(48/53)。无医源性撕裂、眼内出血、眼内炎等严重并发症发生。结论玻璃体切除术联合内限制膜剥离和后巩膜加固治疗退行性近视黄斑裂孔安全有效。关键词:近视;退行性;洞,黄斑;玻璃体切除术;加固,后巩膜;剥皮,膜,限制,内部
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引用次数: 0
Vitrectomy with intraocular cyclophotocoagulation for the treatment of neovascular glaucoma 玻璃体切除术联合眼内光凝治疗新生血管性青光眼
Pub Date : 2019-12-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.12.002
Xue-dong Rong, wang guangming
Objective To evaluate the efficacy of vitrectomy combined with intraocular cyclophotocoagulation for the treatment of neovascular glaucoma (NVG) secondary to proliferative diabetic retinopathy (PDR). Methods The data of 52 eyes of 52 patients with NVG secondary to PDR in this hospital from Sep. 2017 to Apr. 2018 were analyzed retrospectively. All patients underwent intravitreal ranibizumab injection. Vitrectomy and panretinal photocoagulation were performed at 7 days after injection. There were 26 cases in clinical trial group and 26 cases in control group. Vitrectomy and intraocular cyclophotocoagulation were performed in the trial group. Cyclophotocoagulation was performed with 20 G laser fiber during the operation. The control group accepted vitrectomy alone. Results There was no significant difference in baseline data between the two groups (P>0.05). At 6 months postoperatively, the obvious iris new blood vessels were subsided in 17 eyes (65.4%) of the trial group and 15 eyes (57.7%) of the control group, respectively (P=0.569). There was no significant difference in BCVA between the two groups at 1 week, 3 months and 6 months after operation (P=0.596, 0.587, 0.671), and the intraocular pressure in the trial group was lower than that in the control group(P=0.003, 0.000, 0.000). Conclusion Intravitreal injection of ranibizumb combined with vitrectomy and intraocular cyclophotocoagulation for NVG secondary to PDR can promote neovascular regression and effectively reduce intraocular pressure. Key words: Retinopathy, diabetic, proliferative; Glaucoma, neovascular; Vitrectomy; Ranibizumab, intravitreal injection; Cyclophotocoagulation
目的评价玻璃体切除术联合眼内光凝治疗增殖性糖尿病视网膜病变(PDR)继发的新生血管性青光眼(NVG)的疗效。方法回顾性分析2017年9月~ 2018年4月该院52例继发PDR的NVG患者的52眼资料。所有患者均接受玻璃体内注射雷尼单抗。注射后第7天行玻璃体切除和全视网膜光凝。临床试验组26例,对照组26例。试验组行玻璃体切除术和眼内光凝术。术中采用20g激光光纤进行光凝。对照组仅行玻璃体切除术。结果两组患者基线资料比较,差异无统计学意义(P>0.05)。术后6个月,实验组和对照组分别有17眼(65.4%)和15眼(57.7%)虹膜新生血管明显消退(P=0.569)。两组患者术后1周、3个月、6个月的BCVA差异无统计学意义(P=0.596、0.587、0.671),且实验组眼压低于对照组(P=0.003、0.000、0.000)。结论雷尼单抗玻璃体内注射联合玻璃体切除和眼内光凝治疗PDR继发性NVG可促进新生血管消退,有效降低眼压。关键词:视网膜病变,糖尿病,增生性;新生血管性青光眼;玻璃体切除术;雷尼单抗,玻璃体内注射;Cyclophotocoagulation
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引用次数: 0
The efficacy of minimally invasive repair for laceration of inferior lacrimal canaliculus 微创修复泪下小管撕裂伤的疗效观察
Pub Date : 2019-12-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.12.006
Lei Zaizhi
Objective To evaluate the clinical efficacy of minimally invasive repair and anastomosis of inferior lacrimal canaliculus laceration. Methods The data of 83 eyes of 83 patients with inferior lacrimal canaliculus laceration in this hospital from Dec. 2015 to Apr. 2018 were retrospectively analyzed. The study included 29 cases in the observation group and 54 cases in the control group. All cases performed surgery under the operating microscope, and the broken end of the nasal side were directly probed along the wound edge during operation. The control group adopted the ordinary anastomosis method of dual anterograde intubation with silicone stent. The observation group adopted minimally invasive anastomosis method. The lacrimal duct stent was placed into the lacrimal duct to anastomose the inferior lacrimal canaliculus laceration. All cases were followed up for 6 months. Results The operation time of the observation group was significantly shorter than that of the control group, and the difference was statistically significant (P=0.000). There was no significant difference in the recovery rate between the two groups (P=0.807). The incidence rate of puncta slitting in the observation group were significantly lower than that in the control group (P=0.046). Conclusion The minimally invasive repair for inferior lacrimal canaliculus rupture does not cause secondary injury, and the efficacy is definite. Key words: Laceration, lacrimal canaliculus; Repair, minimally invasive; Efficacy
目的探讨下泪小管撕裂伤微创修复吻合的临床疗效。方法回顾性分析2015年12月至2018年4月该院83例泪下小管撕裂患者83只眼的资料。观察组29例,对照组54例。所有病例均在手术显微镜下进行手术,术中沿创口边缘直接探查鼻侧断端。对照组采用硅胶支架双顺行插管的普通吻合方法。观察组采用微创吻合法。将泪管支架置入泪管,吻合下泪小管裂口。所有病例均随访6个月。结果观察组手术时间明显短于对照组,差异有统计学意义(P=0.000)。两组的回收率差异无统计学意义(P=0.807)。观察组点状切口发生率显著低于对照组(P=0.046)。结论微创修复下泪小管破裂无继发性损伤,疗效确切。关键词:撕裂伤;泪小管;修复,微创;功效
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引用次数: 0
Progress in diagnosis and treatment of lacrimal canalicular laceration 泪小管撕裂伤的诊断与治疗进展
Pub Date : 2019-12-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.12.016
Zhuo-fan Chen, Jin Jiang, Chaoyang Hong
Lacrimal canalicular laceration is the most common wound type in lacrimal duct system, which is complicated and the treatment is difficult.Lacrimal canalicular laceration requires precise contrapuntal anastomosis, otherwise permanent epiphora and complications such as inner canthus deformity and eyelid ectropion will occur, which will bring great physical and mental effects to patients.In recent years, great progress has been made in the research and clinical treatment of lacrimal canalicular laceration.This paper briefly reviewed the etiology, surgical indications, repair time, localization of broken ends, catheterization methods and time of catheter removal. Key words: Laceration, canalicular, lacrimal; Diagnosis; Treatment; Progress; Review
泪道小管撕裂伤是泪道系统最常见的创伤类型,其伤情复杂,治疗困难。泪小管撕裂需要精确的对位吻合,否则会出现永久性上睑下垂及内眦畸形、眼睑外翻等并发症,给患者带来极大的身心影响。近年来,泪小管撕裂伤的研究和临床治疗取得了很大进展。本文就其病因、手术指征、修复时间、断端定位、置管方法及拔管时间作一综述。关键词:撕裂伤,小管,泪道;诊断;治疗;进步;审查
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引用次数: 0
Distribution and drug susceptibility of pathogenic bacteria in 1 287 cases of neonatal dacryocystitis 1 287例新生儿泪囊炎病原菌分布及药敏分析
Pub Date : 2019-12-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.12.011
Xian Li, Guizhen Zhang
Objective To analyze the distribution of pathogenic bacteria and drug susceptibility results in 1 287 cases of neonatal dacryocystitis in Henan Province. Methods Retrospective analysis.The pathogen culture and drug susceptibility results of 1 287 cases of dacryocystorhin in this hospital from Jan.2018 to Dec.2018 were collected. Results A total of 1 099 pathogenic bacteria were detected, and the detection rate was 85.4%.There were 618 Gram-positive bacteria strains (56.2%), included Staphylococcus aureus (19.3%), Staphylococcus epidermidis (17.5%), Streptococcus mutans (10.4%). There were 458 Gram-negative bacteria strains (41.7%), included Haemophilus influenzae (17.0%), Escherichia coli (11.5%), Klebsiella pneumoniae (7.4%). There were 23 fungi strains (2.1%). Gram-positive bacteria was the most sensitive to Vancomycin (98.8%), followed by levofloxacin (92.4%). Gram-negative bacteria was the most sensitive to imipenem (96.1%), followed by ciprofloxacin (91.4%). The resistance rate of Gram-positive bacteria and Gram-negative bacteria was the highest for erythromycin. Conclusion Gram-positive bacteria are higher than Gram-negative bacteria in the pathogenic bacteria of neonatal dacryocystitis. Key words: Dacryocystitis, neonatal; Bacteria, pathogenic; Sensitivity, drug
目的分析河南省1 287例新生儿泪囊炎病原菌分布及药敏结果。方法回顾性分析。收集2018年1月至12月该院1 287例泪囊素的病原菌培养及药敏结果。结果共检出病原菌1 099株,检出率为85.4%。革兰氏阳性菌618株(56.2%),其中金黄色葡萄球菌(19.3%)、表皮葡萄球菌(17.5%)、变形链球菌(10.4%)。革兰氏阴性菌458株(41.7%),其中流感嗜血杆菌(17.0%)、大肠杆菌(11.5%)、肺炎克雷伯菌(7.4%)。共有23株真菌(2.1%)。革兰氏阳性菌对万古霉素最敏感(98.8%),其次为左氧氟沙星(92.4%)。革兰氏阴性菌对亚胺培南最敏感(96.1%),其次为环丙沙星(91.4%)。革兰氏阳性菌和革兰氏阴性菌对红霉素耐药率最高。结论新生儿泪囊炎病原菌中革兰氏阳性菌多于革兰氏阴性菌。关键词:泪囊炎;新生儿;细菌致病性;敏感性,药物
{"title":"Distribution and drug susceptibility of pathogenic bacteria in 1 287 cases of neonatal dacryocystitis","authors":"Xian Li, Guizhen Zhang","doi":"10.3760/CMA.J.ISSN.2095-1477.2019.12.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2019.12.011","url":null,"abstract":"Objective \u0000To analyze the distribution of pathogenic bacteria and drug susceptibility results in 1 287 cases of neonatal dacryocystitis in Henan Province. \u0000 \u0000 \u0000Methods \u0000Retrospective analysis.The pathogen culture and drug susceptibility results of 1 287 cases of dacryocystorhin in this hospital from Jan.2018 to Dec.2018 were collected. \u0000 \u0000 \u0000Results \u0000A total of 1 099 pathogenic bacteria were detected, and the detection rate was 85.4%.There were 618 Gram-positive bacteria strains (56.2%), included Staphylococcus aureus (19.3%), Staphylococcus epidermidis (17.5%), Streptococcus mutans (10.4%). There were 458 Gram-negative bacteria strains (41.7%), included Haemophilus influenzae (17.0%), Escherichia coli (11.5%), Klebsiella pneumoniae (7.4%). There were 23 fungi strains (2.1%). Gram-positive bacteria was the most sensitive to Vancomycin (98.8%), followed by levofloxacin (92.4%). Gram-negative bacteria was the most sensitive to imipenem (96.1%), followed by ciprofloxacin (91.4%). The resistance rate of Gram-positive bacteria and Gram-negative bacteria was the highest for erythromycin. \u0000 \u0000 \u0000Conclusion \u0000Gram-positive bacteria are higher than Gram-negative bacteria in the pathogenic bacteria of neonatal dacryocystitis. \u0000 \u0000 \u0000Key words: \u0000Dacryocystitis, neonatal; Bacteria, pathogenic; Sensitivity, drug","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83553275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of clinical efficacy between suture embedding method and bandage contact lens in pterygium excision 缝合埋点法与绷带接触镜在翼状胬肉切除术中的临床疗效比较
Pub Date : 2019-12-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.12.012
Qianyin Zheng
Objective To compare the clinical efficacy between suture embedding method in pterygium excision and bandage contact lens after pterygium excision. Methods A prospective, randomized and controlled case study. The data of 106 eyes of 106 patients who underwent pterygium excision combined with autologous conjunctival flap graft transplantation in this hospital from Aug. 2017 to Aug. 2018 were collected and analyzed. All patients were divided into three groups randomly, included suture embedding group, bandage contact lens group and control group. Results The pain was assessed with visual analogue scale (VAS). The scores in bandage contact lens group was less than that in suture embedding group at 1day postoperatively(P=0.001). There was no significant difference of pain score between bandage contact lens group and suture embedding group at 3 and 7 days after operation(P=0.213, 0.676). The area of corneal epithelium fluorescent staining in bandage contact lens group were less than that in suture embedding group at 1 and 3 days after operation (P=0.001, 0.020). There was no significant difference between bandage contact lens group and suture embedding group at 7 days after operation in corneal epithelium fluorescent staining area (P=0.173). Conclusion Application of bandage contact lens after pterygium excision in alleviation of corneal irritation and pain is better than suture embedding method. And bandage contact lens can promote corneal epithelial healing effectively. Key words: Surgery, pterygium; Bandage contact lens, corneal; Suture embedding
目的比较缝合埋点法在翼状胬肉切除术中的临床疗效与翼状胬肉切除术后绷带接触镜的疗效。方法采用前瞻性、随机对照病例研究。收集我院2017年8月至2018年8月行翼状胬肉切除联合自体结膜瓣移植的106例患者106只眼的资料进行分析。所有患者随机分为三组:包埋缝线组、绷带隐形眼镜组和对照组。结果采用视觉模拟评分法(VAS)对疼痛进行评定。术后1d,绷带隐形眼镜组评分低于缝线埋置组(P=0.001)。术后3 d、7 d绷带隐形眼镜组与包埋缝线组疼痛评分差异无统计学意义(P=0.213、0.676)。术后1、3 d,绷带隐形眼镜组角膜上皮荧光染色面积均小于缝线包埋组(P=0.001、0.020)。术后7 d角膜上皮荧光染色面积绷带隐形眼镜组与缝线包埋组比较差异无统计学意义(P=0.173)。结论翼状胬肉切除术后应用绷带接触镜减轻角膜刺激和疼痛的效果优于包埋缝合。绷带式隐形眼镜能有效促进角膜上皮愈合。关键词:外科;翼状胬肉;绷带隐形眼镜、角膜;缝合嵌入
{"title":"Comparison of clinical efficacy between suture embedding method and bandage contact lens in pterygium excision","authors":"Qianyin Zheng","doi":"10.3760/CMA.J.ISSN.2095-1477.2019.12.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2019.12.012","url":null,"abstract":"Objective \u0000To compare the clinical efficacy between suture embedding method in pterygium excision and bandage contact lens after pterygium excision. \u0000 \u0000 \u0000Methods \u0000A prospective, randomized and controlled case study. The data of 106 eyes of 106 patients who underwent pterygium excision combined with autologous conjunctival flap graft transplantation in this hospital from Aug. 2017 to Aug. 2018 were collected and analyzed. All patients were divided into three groups randomly, included suture embedding group, bandage contact lens group and control group. \u0000 \u0000 \u0000Results \u0000The pain was assessed with visual analogue scale (VAS). The scores in bandage contact lens group was less than that in suture embedding group at 1day postoperatively(P=0.001). There was no significant difference of pain score between bandage contact lens group and suture embedding group at 3 and 7 days after operation(P=0.213, 0.676). The area of corneal epithelium fluorescent staining in bandage contact lens group were less than that in suture embedding group at 1 and 3 days after operation (P=0.001, 0.020). There was no significant difference between bandage contact lens group and suture embedding group at 7 days after operation in corneal epithelium fluorescent staining area (P=0.173). \u0000 \u0000 \u0000Conclusion \u0000Application of bandage contact lens after pterygium excision in alleviation of corneal irritation and pain is better than suture embedding method. And bandage contact lens can promote corneal epithelial healing effectively. \u0000 \u0000 \u0000Key words: \u0000Surgery, pterygium; Bandage contact lens, corneal; Suture embedding","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75551530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of chalazion forcep in excision of eyelid margin small tumor 睑缘小肿瘤切除中的应用
Pub Date : 2019-12-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.12.015
Junping Li, Yuhong Wang
Objective To investigate application of chalazion forcep in excision of eyelid margin small tumor. Methods The clinical data of 126 eyes of 126 patients with eyelid margin small tumors in this hospital from Jul. 2016 to Dec. 2018 were retrospectively analyzed. There were 54 eyes of 54 patients with chalazion forcep and 72 eyes of 72 patients with traditional resection. The operation time, the cases used photocoagulation during the operation and surgical efficacy were compared between the two groups. Results The operation time in chalazion forcep group [(30.70± 5.96) min] was shorter than that of the conventional resection group [(43.86±8.99) min]. The difference was statistically significant (P 0.05). Conclusion Application of chalazion forcep in the treatment of eyelid margin tumor improves the efficacy of operation. Key words: Forcep, chalazion; Excision, tumor, eyelid margin
目的探讨斜拉钳在睑缘小肿瘤切除术中的应用。方法回顾性分析本院2016年7月至2018年12月收治的126例眼睑缘小肿瘤患者126只眼的临床资料。54例患者中有54眼采用斜拉钳切除,72例患者中有72眼采用传统切除。比较两组手术时间、术中使用光凝的病例数及手术疗效。结果裂孔钳组手术时间[(30.70±5.96)min]短于常规切除组[(43.86±8.99)min]。差异有统计学意义(p0.05)。结论应用睑缘钳治疗睑缘肿瘤可提高手术疗效。关键词:镊子;皲裂;切除,肿瘤,眼睑缘
{"title":"Application of chalazion forcep in excision of eyelid margin small tumor","authors":"Junping Li, Yuhong Wang","doi":"10.3760/CMA.J.ISSN.2095-1477.2019.12.015","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2019.12.015","url":null,"abstract":"Objective \u0000To investigate application of chalazion forcep in excision of eyelid margin small tumor. \u0000 \u0000 \u0000Methods \u0000The clinical data of 126 eyes of 126 patients with eyelid margin small tumors in this hospital from Jul. 2016 to Dec. 2018 were retrospectively analyzed. There were 54 eyes of 54 patients with chalazion forcep and 72 eyes of 72 patients with traditional resection. The operation time, the cases used photocoagulation during the operation and surgical efficacy were compared between the two groups. \u0000 \u0000 \u0000Results \u0000The operation time in chalazion forcep group [(30.70± 5.96) min] was shorter than that of the conventional resection group [(43.86±8.99) min]. The difference was statistically significant (P 0.05). \u0000 \u0000 \u0000Conclusion \u0000Application of chalazion forcep in the treatment of eyelid margin tumor improves the efficacy of operation. \u0000 \u0000 \u0000Key words: \u0000Forcep, chalazion; Excision, tumor, eyelid margin","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84002250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the efficacy between conbercept and ranibizumab in the treatment of wet macular degeneration conbercept与雷尼单抗治疗湿性黄斑变性的疗效比较
Pub Date : 2019-12-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.12.010
Xuan Zhang, Ping Liu, Yanli Li
Objective To compare the efficacy between intravitreal injection conbercept and ranibizumab in the treatment of wet age-related macular degeneration(AMD). Methods The clinical data of 40 eyes of 40 patients with wet AMD from Feb. 2017 to Aug. 2018 in this hospital were analyzed retrospectively. Group A, 20 eyes of 20 cases, received conbercept and group B, 20 eyes of 20 cases, received ranibizumab. All patients underwent intravitreal injection once a month for three consecutive times.The follow-up time was 3 months. Results The visual acuity at 1 week, 1 and 3 months after intravitreal injection was better than that before injection (P 0.05). There was no significant difference between the two groups at different time after injection (P=0.839, 0.402, 0.849). Central macular thickness were decreased in both groups after injection compared with that before injection (P<0.05), but the difference between the two groups was not statistically significant (P=0.885, 0.476, 0.634). Choroidal thickness of the two groups decreased after injection (P<0.05), but the difference between the two groups was not statistically significant (P=0.280, 0.831, 0.093). Conclusion Intravitreal injection of conbercept or ranibizumab can improve visual acuity, ameliorate macular structure, and decrease choroidal thickness for the treatment of wet age-related macular degeneration. There is no significant difference between the two drugs. Key words: Degeneration, macular, age-related, wet; Conbercept, Ranibizumab, intravitreal injection; Efficacy, clinical
目的比较雷尼单抗治疗湿性老年性黄斑变性(AMD)的疗效。方法回顾性分析我院2017年2月至2018年8月收治的40例湿性AMD患者40只眼的临床资料。A组20例20眼接受conberept治疗,B组20例20眼接受雷尼单抗治疗。所有患者均接受玻璃体注射,每月1次,连续3次。随访时间为3个月。结果玻璃体内注射后1周、1、3个月视力优于注射前(P < 0.05)。注射后不同时间两组间差异无统计学意义(P=0.839, 0.402, 0.849)。两组注射后黄斑中央厚度均较注射前降低(P<0.05),但两组间差异无统计学意义(P=0.885、0.476、0.634)。两组注射后脉络膜厚度均降低(P<0.05),但两组间差异无统计学意义(P=0.280、0.831、0.093)。结论conberept或雷尼单抗玻璃体内注射治疗湿性老年性黄斑变性可提高视力,改善黄斑结构,减少脉络膜厚度。两种药物无显著差异。关键词:变性,黄斑,年龄相关性,湿性;Conbercept,雷尼单抗,玻璃体内注射;功效、临床
{"title":"Comparison of the efficacy between conbercept and ranibizumab in the treatment of wet macular degeneration","authors":"Xuan Zhang, Ping Liu, Yanli Li","doi":"10.3760/CMA.J.ISSN.2095-1477.2019.12.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2019.12.010","url":null,"abstract":"Objective \u0000To compare the efficacy between intravitreal injection conbercept and ranibizumab in the treatment of wet age-related macular degeneration(AMD). \u0000 \u0000 \u0000Methods \u0000The clinical data of 40 eyes of 40 patients with wet AMD from Feb. 2017 to Aug. 2018 in this hospital were analyzed retrospectively. Group A, 20 eyes of 20 cases, received conbercept and group B, 20 eyes of 20 cases, received ranibizumab. All patients underwent intravitreal injection once a month for three consecutive times.The follow-up time was 3 months. \u0000 \u0000 \u0000Results \u0000The visual acuity at 1 week, 1 and 3 months after intravitreal injection was better than that before injection (P 0.05). There was no significant difference between the two groups at different time after injection (P=0.839, 0.402, 0.849). Central macular thickness were decreased in both groups after injection compared with that before injection (P<0.05), but the difference between the two groups was not statistically significant (P=0.885, 0.476, 0.634). Choroidal thickness of the two groups decreased after injection (P<0.05), but the difference between the two groups was not statistically significant (P=0.280, 0.831, 0.093). \u0000 \u0000 \u0000Conclusion \u0000Intravitreal injection of conbercept or ranibizumab can improve visual acuity, ameliorate macular structure, and decrease choroidal thickness for the treatment of wet age-related macular degeneration. There is no significant difference between the two drugs. \u0000 \u0000 \u0000Key words: \u0000Degeneration, macular, age-related, wet; Conbercept, Ranibizumab, intravitreal injection; Efficacy, clinical","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76656909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical research on corneal biomechanical changes after keratoconus collagen cross-linking 圆锥角膜胶原交联后角膜生物力学变化的临床研究
Pub Date : 2019-12-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.12.001
Hongchao Zhao
Objective To observe corneal biomechanical changes in patients with keratoconus after corneal collagen cross-linking. Methods Prospective self-control study. Twenty-three eyes of 17 patients with primary keratoconus from Jan. 2018 to Jun. 2018 in Zhengzhou Second Hospital were analyzed. The age of patients ranged from 13 to 28 years, with average of (16.4±2.8) years. All cases were treated with riboflavin/ultraviolet A (UVA)-induced rapid epithelium-off corneal collagen cross-linking. All cases were observed with Corvis ST visualized corneal biomechanical measurement instrument and followed up for 12 months. Results The best corrected visual acuity (LogMAR) after operation increased from 0.42±0.19 to 0.29±0.15 (t=-8.043, P=0.000). The equivalent spherical diopter and the maximum curvature of the anterior corneal surface were decreased (t=-4.183, -5.188, P=0.000, 0.000). The thinnest corneal thickness postoperative was decreased compared with that before operation(t=-3.984, P=0.001). The first flattening time postoperative increased (t=7.793, P=0.000). The second flattening time and the maximum indentation depth decreased (t=-9.075, P=0.000, t=-3.280, P=0.003). Conclusion The visual acuity, corneal morphology and biomechanical parameters after the rapid epithelium-off corneal collagen cross-linking in patients with primary keratoconus are ameliorated significantly. Key words: Keratoconus; Cross-linking, collagen, corneal; Biomechanics, cornea
目的观察圆锥角膜患者角膜胶原交联后角膜的生物力学变化。方法前瞻性自我控制研究。对郑州市第二医院2018年1月至2018年6月17例原发性圆锥角膜患者23只眼进行分析。患者年龄13 ~ 28岁,平均(16.4±2.8)岁。所有病例均采用核黄素/紫外线A (UVA)诱导的角膜胶原快速交联治疗。所有病例均采用Corvis ST可视化角膜生物力学测量仪进行观察,随访12个月。结果术后最佳矫正视力(LogMAR)由0.42±0.19提高至0.29±0.15 (t=-8.043, P=0.000)。等效球面屈光度和角膜前表面最大曲率降低(t=-4.183, -5.188, P=0.000, 0.000)。术后最薄角膜厚度较术前降低(t=-3.984, P=0.001)。术后第一次平化时间增加(t=7.793, P=0.000)。第二次压平时间和最大压痕深度减小(t=-9.075, P=0.000, t=-3.280, P=0.003)。结论角膜胶原快速交联后,原发性圆锥角膜患者的视力、角膜形态及生物力学参数均有明显改善。关键词:圆锥角膜;交联,胶原蛋白,角膜;生物力学,角膜
{"title":"Clinical research on corneal biomechanical changes after keratoconus collagen cross-linking","authors":"Hongchao Zhao","doi":"10.3760/CMA.J.ISSN.2095-1477.2019.12.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2019.12.001","url":null,"abstract":"Objective \u0000To observe corneal biomechanical changes in patients with keratoconus after corneal collagen cross-linking. \u0000 \u0000 \u0000Methods \u0000Prospective self-control study. Twenty-three eyes of 17 patients with primary keratoconus from Jan. 2018 to Jun. 2018 in Zhengzhou Second Hospital were analyzed. The age of patients ranged from 13 to 28 years, with average of (16.4±2.8) years. All cases were treated with riboflavin/ultraviolet A (UVA)-induced rapid epithelium-off corneal collagen cross-linking. All cases were observed with Corvis ST visualized corneal biomechanical measurement instrument and followed up for 12 months. \u0000 \u0000 \u0000Results \u0000The best corrected visual acuity (LogMAR) after operation increased from 0.42±0.19 to 0.29±0.15 (t=-8.043, P=0.000). The equivalent spherical diopter and the maximum curvature of the anterior corneal surface were decreased (t=-4.183, -5.188, P=0.000, 0.000). The thinnest corneal thickness postoperative was decreased compared with that before operation(t=-3.984, P=0.001). The first flattening time postoperative increased (t=7.793, P=0.000). The second flattening time and the maximum indentation depth decreased (t=-9.075, P=0.000, t=-3.280, P=0.003). \u0000 \u0000 \u0000Conclusion \u0000The visual acuity, corneal morphology and biomechanical parameters after the rapid epithelium-off corneal collagen cross-linking in patients with primary keratoconus are ameliorated significantly. \u0000 \u0000 \u0000Key words: \u0000Keratoconus; Cross-linking, collagen, corneal; Biomechanics, cornea","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83041608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
中华眼外伤职业眼病杂志
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