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Anterior chamber gas injection for the treatment of detachment of corneal Descemet’s membrane after cataract surgery 前房气体注射治疗白内障术后角膜前膜脱离
Pub Date : 2019-11-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.11.005
Xia Huang, Jun Yuan, Zhi-gang Zhao
Objective To evaluate the clinical efficacy of anterior chamber gas injection for the treatment of detachment of corneal Descemet’s membrane after cataract surgery. Methods The data of 31 eyes of 31 patients with corneal Descemet’s membrane detachment after phacoemulsification in this hospital from Nov. 2015 to Nov. 2018 were retrospectively analyzed.Anterior chamber gas injections were performed at 1 day after surgery. The patients were followed up for 3 months. Results The corneal Descemet’s membranes restored well after surgery in 29 patients(93.55%). One patient(3.23%) with local corneal Descemet’s membrane detachment restored, after using regional anti-inflammatory and hypertonic eye drips. One patient (3.23%) with partial detachment, anterior chamber gas injection was performed again. All these 31 patients had visual acuity improvements after surgery(t=6.926, P=0.000). Conclusion Anterior chamber gas injection in early stage is a safe and effective method for corneal Descemet’s membrane detachment after cataract surgery. Key words: Detachment, membrane, Descemet’s, corneal; Surgery, cataract; Injection, gas, anterior chamber
目的评价前房气体注射治疗白内障术后角膜前膜脱离的临床疗效。方法回顾性分析我院2015年11月至2018年11月31例超声乳化术后角膜Descemet膜脱离患者31只眼的资料。术后第1天进行前房气体注射。随访3个月。结果29例(93.55%)患者术后角膜Descemet膜恢复良好。1例(3.23%)局部角膜Descemet膜脱离经局部抗炎和高渗滴眼后恢复。1例(3.23%)部分脱离,再次行前房注气术。31例患者术后视力均有改善(t=6.926, P=0.000)。结论早期前房注气治疗白内障术后角膜Descemet膜脱离是一种安全有效的治疗方法。关键词:脱离,膜,Descemet,角膜;手术,白内障;注射,气体,前房
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引用次数: 0
Analysis of the corneal spherical aberration in patients with primary angle-closure glaucoma with cataract 原发性闭角型青光眼合并白内障患者角膜球差的分析
Pub Date : 2019-11-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.11.003
Xiao-Hong Zhu, Wen-jie Liu, Jun-hong Zhao
Objective To analyze the distribution and related factors of the spherical aberration in patients with primary angle-closure glaucoma and cataract. Methods Retrospective series of case study. The data of 154 eyes of 120 patients of primary angle-closure glaucoma with cataract from Nov. 2018 to Mar. 2019 in this hospital were analyzed. Pentacam HR anterior segment analyzer (Oculus, Germany) was used to measure and analyse datas. Results The average age of patients was (68.00±9.95) years, ranged from 33 to 85 years. The average spherical aberration was (0.35±0.16) μm, ranged from -0.35 μm to 0.76 μm. A positive correlation was found between spherical aberration and age(r=0.287, P=0.000), spherical aberration and mean corneal refractive power(r= 0.170, P=0.035). A negative correlation was found between spherical aberration and corneal refractive power of posterior surface(r=-0.164, P=0.042). There were no correlation between spherical aberration and corneal diameter, corneal thickness, corneal volume and axis length(r=-0.034, -0.149, -0.126, -0.123, P=0.681, 0.066, 0.119, 0.134). With residual spherical aberration(0.1±0.05)μm as the target, 90 eyes (58.4%) were corrected by different aspheric IOLs(0, -0.20 μm, -0.27 μm). Conclusion Corneal spherical aberration in patients with primary angle-closure glaucoma and cataract is larger than that reported in other populations(+ 0.27 μm), and with larger fluctuation range. A suitable IOL should be selected according to the preoperative comprehensive evaluation of personalized spherical aberrations, pupil, visual field and the injury of the optic nerve. Key words: Glaucoma; Cataract; Aberration, spheric, corneal; Lens, intraocular, aspheric
目的分析原发性闭角型青光眼合并白内障患者的球差分布及相关因素。方法回顾性系列病例研究。对该院2018年11月至2019年3月120例原发性闭角型青光眼合并白内障患者154只眼的资料进行分析。使用Pentacam HR前段分析仪(德国Oculus)测量和分析数据。结果患者平均年龄(68.00±9.95)岁,年龄范围33 ~ 85岁。平均球差为(0.35±0.16)μm,范围为-0.35 ~ 0.76 μm。球差与年龄呈正相关(r=0.287, P=0.000),球差与平均角膜屈光度呈正相关(r= 0.170, P=0.035)。球差与角膜后表面屈光度呈负相关(r=-0.164, P=0.042)。球差与角膜直径、角膜厚度、角膜体积、角膜轴长无相关性(r=-0.034、-0.149、-0.126、-0.123,P=0.681、0.066、0.119、0.134)。以残余球差(0.1±0.05)μm为目标,采用不同的非球面iol(0、-0.20 μm、-0.27 μm)对90只眼(58.4%)进行了校正。结论原发性闭角型青光眼合并白内障患者的角膜球差大于其他人群(+ 0.27 μm),且波动幅度较大。术前应综合评估个体化球差、瞳孔、视野及视神经损伤情况,选择合适的人工晶体。关键词:青光眼;白内障;像差,球,角膜;晶状体,眼内,非球面
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引用次数: 0
Cyclophotocoagulation under operating microscopy for the treatment of refractory glaucoma 手术显微镜下光凝治疗难治性青光眼
Pub Date : 2019-11-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.11.010
Zhengru Huang
Objective To evaluate the efficacy of cyclophotocoagulation under operating microscopy for the treatment of refractory glaucoma. Methods The clinical data of 31 eyes of 31 cases with refractory glaucoma from Jan. 2017 to Apr. 2018 in this hospital were analyzed retrospectively. All patients underwent cyclophotocoagulation under operating microscopy via pars plana. The follow-up time was 12 months at least. Results Preoperative intraocular pressure (IOP) was (34.8±8.5) mmHg (1 mmHg=0.133 kPa). Postoperative IOP at 1 day, 7 days, 1, 6 and 12 months were (18.5±6.3) mmHg, (17.1±3.7) mmHg, (16.4±2.7) mmHg, (16.2±2.9) mmHg and (16.2±3.2) mmHg, respectively. The difference were statistically significant between before and after operation (P=0.000). The success rate of surgery at the end of follow-up was 74.2%. Postoperative ultrasonic biomicroscopy showed the complete atrophy of ciliary body in the cyclophotocoagulation sites. Conclusion Cyclophotocoagulation under operating microscopy was effective and safe for the treatment of refractory glaucoma. Key words: Glaucoma, refractory; Cyclophotocoagulation, under operating microscopy
目的评价手术显微镜下光凝治疗难治性青光眼的疗效。方法回顾性分析我院2017年1月~ 2018年4月收治的31例难治性青光眼患者31只眼的临床资料。所有患者均在手术显微镜下经平面部行光凝治疗。随访时间至少为12个月。结果术前眼压(IOP)为(34.8±8.5)mmHg (1 mmHg=0.133 kPa)。术后1天、7天、1、6、12个月IOP分别为(18.5±6.3)mmHg、(17.1±3.7)mmHg、(16.4±2.7)mmHg、(16.2±2.9)mmHg和(16.2±3.2)mmHg。手术前后差异有统计学意义(P=0.000)。随访结束时手术成功率为74.2%。术后超声生物显微镜检查显示睫状体光凝部位完全萎缩。结论手术显微镜下光凝治疗难治性青光眼安全有效。关键词:青光眼;难治性;操作显微镜下的光凝
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引用次数: 1
Clinical observation on retroillumination assisted continuous circular capsulorhexis 逆光辅助连续环形撕囊术的临床观察
Pub Date : 2019-11-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.11.002
Shuai Wang
Objective To observe the application of illuminator guided retroillumination assisted continuous circular capsulorhexis. Methods A prospective study. Thirty eyes of 30 cases with cataract with vitreous hemorrhage, with poor fundus red reflex, from Sep. 2016 to Aug. 2017 in this hospital, were enrolled. After the ophthalmic endoilluminator was inserted into the vitreous, the endoilluminator was irradiated forward from the posterior lens capsule, then continuous circular capsulorhexis was performed. Phacoemulsification and vitrectomy were carried out routinely. The followed-up time was 8-12 months. Results The continuous circular capsulorhexis and phacoemulsification were performed successfully in all 30 eyes without any posterior capsule rupture. Vitreous hemaorrhage was completely removed, and retinal diseases was properly treated. The visual acuity before operation was HM-0.04 in 27 eyes(90.00%) and 0.05 in 3 eyes(10.00%). Postoperative visual acuity of all patients were 0.05 or better. The difference of visual acuity was statistically significant between before and after operation (χ2=49.091, P=0.000). Conclusion The illuminator guided retroillumination assisted continuous circular capsulorhexis can effectively solve the difficulty of poor red light reflex for cataract patients with vitreous hemorrhage. Key words: Capsulorhexis, circular, continuous, retroillumination; Phacoemulsification, lens; Vitrectomy
目的观察照明器引导下反照辅助连续环形撕囊术的应用。方法前瞻性研究。选取本院2016年9月至2017年8月收治的30例伴有玻璃体出血、眼底红色反射差的白内障患者30只眼。将眼球内照器置入玻璃体后,从晶状体后囊向前照射,进行连续的圆形撕囊术。常规行超声乳化术和玻璃体切除术。随访8 ~ 12个月。结果30只眼均行连续环形撕囊和超声乳化术,无后囊膜破裂。玻璃体出血完全清除,视网膜疾病得到妥善治疗。术前视力HM-0.04 27眼(90.00%),0.05 3眼(10.00%)。术后视力均在0.05及以上。手术前后视力差异有统计学意义(χ2=49.091, P=0.000)。结论照明器引导下逆行照明辅助连续环形摘除术能有效解决玻璃体出血白内障患者红光反射差的困难。关键词:撕囊;圆形;连续;超声乳化,镜头;玻璃体切除术
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引用次数: 0
Efficacy of deep lamellar keratoplasty for the treatment of stromal corneal dystrophy 深板层角膜移植术治疗间质性角膜营养不良的疗效观察
Pub Date : 2019-11-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.11.004
Hui Su, P. Yu, Kun-ming Wang
Objective To evaluate the efficacy of deep lamellar keratoplasty for the treatment of stromal corneal dystrophy. Methods The data of 59 eyes of 49 patients with stromal corneal dystrophy in this hospital from Jan.2012 to Dec.2018 were analyzed retrospectively.All cases were treated with deep lamellar keratoplasty.The follow-up time was 6 months-4 years.The corneal graft and the complications of intra-operation and post-operation were observed. Results The corneal graft remained clear in all cases after surgery. The best corrected visual acuity (BCVA) postoperatively was 0.3 in 8 eyes, 0.4-0.6 in 40 eyes, 0.6-0.8 in 11 eyes. Intraoperative complications included perforation of descemet’s membrane in 5 eyes, postoperative temporary elevation of intraocular pressure in 4 eyes, descemet’s membrane striae in 6 cases and recurrence of primary disease in 3 eyes. No reject reaction occurred after keratoplasty. Conclusion Deep lamellar keratoplasty is a safe and effective method for the treatment of stromal corneal dystrophy. Key words: Keratoplasty, lamellar, deep; Dystrophy, corneal, Stromal
目的评价深板层角膜移植术治疗间质性角膜营养不良的疗效。方法回顾性分析2012年1月~ 2018年12月本院49例间质性角膜营养不良患者59眼的资料。所有病例均行深板层角膜移植术。随访时间6个月~ 4年。观察角膜移植的情况及术中、术后并发症。结果所有病例术后角膜移植物均保持清晰。术后最佳矫正视力(BCVA) 0.3 8眼,0.4 ~ 0.6 40眼,0.6 ~ 0.8 11眼。术中并发症:视网膜膜穿孔5眼,术后暂时性眼压升高4眼,视网膜膜出现条纹6眼,原发疾病复发3眼。角膜移植术后无排斥反应发生。结论深板层角膜移植术是治疗间质性角膜营养不良的一种安全有效的方法。关键词:角膜移植术;板层;深度;营养不良,角膜,基质
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引用次数: 0
Bio-amniotic membrane transplantation combined with anterior corneal stroma puncture for the treatment of recurrent corneal epithelial erosion syndrome 生物羊膜移植联合角膜前基质穿刺治疗复发性角膜上皮侵蚀综合征
Pub Date : 2019-11-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.11.015
Xiaoteng Yan, Fangfang Li, Cao Gu
Objective To evaluate the efficacy of bio-amniotic membrane transplantation combined with anterior corneal stroma puncture in the treatment of recurrent corneal epithelial erosion syndrome. Methods A prospective randomized clinical study. The data of 32 eyes of 27 cases with recurrent corneal epithelial erosion syndrome were analyzed from Jan.2015 to Sep.2018 in the Affiliated Huai’an Hospital of Xuzhou Medical University. All cases were randomly divided into two groups. There were 16 eyes of 13 cases in amniotic membrane transplantation combined with anterior corneal stroma puncture group and 16 eyes of 14 cases in anterior corneal stroma puncture group. The efficacy of operation was evaluated. Results Postoperative pain scores in both groups were significantly lower than those before operation. The difference in pain scores was statistically significant between the two groups on 1 and 3 days after operation (t1=3.693, P=0.001, t3=2.725, P=0.011). The difference in pain scores was not statistically significant between the two groups on 5 days after operation (t5=1.054, P=0.300). There was no significant difference in recurrence rate between the two groups(P=0.151). Conclusion Bio-amniotic membrane transplantation combined with anterior corneal stroma puncture can effectively treat recurrent corneal epithelial erosion syndrome, which has the advantages of low recurrence rate and high comfort after operation. Key words: Transplantation, amniotic membrane; Puncture, anterior stroma, cornea; Erosion, epithelium, cornea
目的探讨生物羊膜移植联合角膜前基质穿刺治疗复发性角膜上皮侵蚀综合征的疗效。方法前瞻性随机临床研究。对徐州医科大学附属淮安医院2015年1月至2018年9月收治的27例复发性角膜上皮侵蚀综合征32眼的临床资料进行分析。所有病例随机分为两组。羊膜移植联合角膜前基质穿刺组13例16眼,角膜前基质穿刺组14例16眼。评价手术疗效。结果两组患者术后疼痛评分均明显低于术前。两组患者术后1、3 d疼痛评分差异有统计学意义(t1=3.693, P=0.001; t3=2.725, P=0.011)。术后5 d两组疼痛评分差异无统计学意义(t5=1.054, P=0.300)。两组复发率比较差异无统计学意义(P=0.151)。结论生物羊膜移植联合角膜前基质穿刺可有效治疗复发性角膜上皮侵蚀综合征,具有复发率低、术后舒适度高的优点。关键词:移植;羊膜;穿刺,前基质,角膜;糜烂,上皮,角膜
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引用次数: 0
Posterior chamber phakic intraocular lens for correction of high myopia 后房型有晶状体人工晶状体矫正高度近视
Pub Date : 2019-11-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.11.007
Zhao Xiaojin, Zhao Hong, Ding Xiang-qi
Objective To observe the clinical efficacy of posterior chamber phakic intraocular lens (ICL)for correction of high myopia. Methods The data of 110 eyes of 55 cases with high myopia(-6.00 D--18.00 D)who received ICL implantation from Dec. 2017 to Sep. 2018 were collected and analyzed retrospectively. The patients were followed up for 3 months. The data were observed and analyzed between preoperative and postoperative. Results The differences of the average uncorrected visual acuity, best corrected visual acuity(LogMAR) and refraction were statistically significant between preoperative and 3 months postoperatively(t=14.580, 13.240, 11.770, P=0.010, 0.021, 0.013). There was significant difference of the root mean square value in the general lower-order aberrations between preoperative and 3 months postoperatively(t=-18.780, P=0.000). The differences in the general higher-order aberrations, 3-order aberrations, 4-order aberrations, and 5-order aberrations root mean square value were not statistically significant between preoperative and 3 months postoperatively(t=-1.278, 0.785, 0.351, 0.457, P=0.125, 0.412, 0.224, 0.324). The differrences of Z40, Z31, Z3-1, Z33, Z3-3 were not statistically significant between preoperative and 3 months postoperatively (t=0.654, 0.545, 0.387, 0.268, 0.578, P=0.547, 0.371, 0.241, 0.187, 0.428). Conclusion Posterior chamber phakic intraocular lens is safe, effective, predictable and stable for correction of high myopia and postoperative visual quality is good. Key words: Lens, intraocular, phakic, posterior chamber; Myopia, high; Visual quality
目的观察后房型人工晶状体(ICL)矫正高度近视的临床疗效。方法回顾性分析2017年12月至2018年9月行ICL植入术的55例高度近视(-6.00 D—18.00 D)患者110眼的资料。随访3个月。对术前和术后的数据进行观察和分析。结果术前与术后3个月平均未矫正视力、最佳矫正视力(LogMAR)及屈光度差异均有统计学意义(t=14.580、13.240、11.770,P=0.010、0.021、0.013)。术前与术后3个月一般低阶像差的均方根值差异有统计学意义(t=-18.780, P=0.000)。术前与术后3个月一般高阶像差、3阶像差、4阶像差、5阶像差均方根值差异均无统计学意义(t=-1.278、0.785、0.351、0.457,P=0.125、0.412、0.224、0.324)。Z40、Z31、Z3-1、Z33、Z3-3术前与术后3个月比较,差异均无统计学意义(t=0.654、0.545、0.387、0.268、0.578,P=0.547、0.371、0.241、0.187、0.428)。结论后房型人工晶状体矫正高度近视安全、有效、可预测、稳定,术后视力质量良好。关键词:晶状体;眼内;晶状体;近视,高;视觉质量
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引用次数: 0
Study of manifestations of dry eye and TGF-β expression after ocular alkali burn 眼碱烧伤后干眼表现及TGF-β表达的研究
Pub Date : 2019-11-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.11.001
Bo Jiang, Tao Li, Man She, Xiaoqian Yao
Objective To investigate the manifestation of dry eye and TGF-β expression in patients after ocular alkali burns. Methods This is a case-control study. Total of 33 eyes of 26 cases with alkali burns of I-IV degrees from Jan.2017 to Jun.2018 in this hospital were selected as observation group, and 10 eyes of 10 cases of normal people were selected as control group. The followed-up time was 3 months. The visual acuity, intraocular pressure, BUT, SchirmerⅠtest, lacrimal rivus height and corneal thickness were observed at 1 day, 1 and 3 months after ocular alkali burn. The protein expression of TGF-β1 and TGF-β2 were examined with western-blot analysis. Results BUT and Schirmer I test in the observation group were lower than those in the control group at 3 months after ocular alkali burn (P<0.05). The corneal thickness and the lacrimal rivus height at each time after ocular alkali burn were higher than those in the control group(P<0.05). The protein expressions of TGF-β1 and TGF-β2 were significantly negatively correlated with BUT(P=0.046, 0.036), and TGF-β2 was significantly positively correlated with corneal thickness (P=0.024). Conclusion Ocular alkali burns can cause dry eye, and the expressions of TGF-β1 and TGF-β2 in tears may be related to the occurrence of dry eye after ocular alkali burn. Key words: Burn, alkali, ocular; Dry eye; OCT; TGF-β1; TGF-β2
目的探讨眼碱烧伤后干眼的表现及TGF-β的表达。方法采用病例-对照研究。选取该院2017年1月至2018年6月26例I-IV度碱烧伤患者33眼作为观察组,选取10例正常人10眼作为对照组。随访时间3个月。分别于眼碱烧伤后1 d、1、3个月观察两组患者的视力、眼压、BUT、SchirmerⅠ试验、泪病毒高度和角膜厚度。western-blot检测TGF-β1、TGF-β2蛋白表达。结果眼碱烧伤后3个月,观察组BUT、Schirmer I测试均低于对照组(P<0.05)。眼碱烧伤后各组角膜厚度、泪病毒高度均高于对照组(P<0.05)。TGF-β1、TGF-β2蛋白表达与BUT呈显著负相关(P=0.046、0.036),TGF-β2蛋白表达与角膜厚度呈显著正相关(P=0.024)。结论眼碱烧伤可引起眼干眼,泪液中TGF-β1和TGF-β2的表达可能与眼碱烧伤后干眼的发生有关。关键词:烧伤,碱,眼;干眼病;10月;转化生长因子-β1;TGF -β2
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引用次数: 0
The efficacy of removal of residual silicone oil droplet with posterior lens capsulotomy 后晶状体囊切开术去除残余硅油滴的效果
Pub Date : 2019-11-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.11.008
M. Yu, Wenjie Wu, D. Yan, Xinna Wu, Ting Yu
Objective To evaluate the safety and efficacy of removal of residual silicone oil droplet with posterior lens capsulotomy. Methods A retrospective study. Total 12 eyes of 12 consecutive patients with residual silicone oil droplet after silicone oil removal from Aug. 2013 to Apr. 2019 were collected in Fujian provincial hospital. There were 10 eyes received posterior lens capsulotomy combined with phacoemulsification, and 2 eyes received posterior lens capsulotomy combined with secondary intraocular lens implantation. The intra-operative complications, postoperative silicone oil droplet residual rate, best corrected visual acuity, intraocular pressure, anterior segment and fundus examination were observed. Results The patients were followed up for 1-69 months. Postoperative visual disturbance symptoms and the best corrected visual acuity were ameliorated in all patients. The visual acuity at the last follow up was 0.3 in 5 eyes (41.7%) and ≥0.5 in 3 eyes (25.0%). No postoperative complication such as increased intraocular pressure, retinal detachment or choroidal detachment occurred. The intraocular lens position were stable during the follow-up period. Conclusion It is a simple, safe and effective way to remove silicone oil droplet with posterior lens capsulotomy. Key words: Capsulotomy, posterior capsule, lens; Phacoemulsification, ultrasonic, lens; Implantation, lens, intraocular
目的评价晶状体后晶体囊切开术去除残余硅油滴的安全性和有效性。方法回顾性研究。收集2013年8月至2019年4月福建省立医院连续12例硅油去除后残留硅油滴滴患者的12只眼。晶状体后囊切除术联合超声乳化摘除10眼,晶状体后囊切除术联合二次人工晶状体植入术2眼。观察术中并发症、术后硅油滴残留率、最佳矫正视力、眼压、前段及眼底检查。结果随访1 ~ 69个月。所有患者术后视力障碍症状及最佳矫正视力均有改善。末次随访视力0.3眼5眼(41.7%),≥0.5眼3眼(25.0%)。术后无眼压升高、视网膜脱离、脉络膜脱离等并发症发生。随访期间,人工晶状体位置稳定。结论晶状体后囊切开术是一种简单、安全、有效的硅油滴取出方法。关键词:囊膜切开术,后囊膜,晶状体;超声乳化、超声、晶状体;植入,晶状体,眼内
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引用次数: 0
Intravitreal ranibizumab injection combined with panretinal photocoagulation for the treatment of neovascular glaucoma 雷尼单抗玻璃体内注射联合全视网膜光凝治疗新生血管性青光眼
Pub Date : 2019-11-25 DOI: 10.3760/CMA.J.ISSN.2095-1477.2019.11.011
Yongcheng Hu, Zhike Zhang, Ping Zhang, Xudong Zhang
Objective To observe the efficacy of intravitreal ranibizumab injection with panretinal photocoagulation for the treatment of neovascular glaucoma. Methods Total of 20 eyes of 20 cases with neovascular glaucoma in Bayannur Federation of Disabled People’s Eye Hospital from Jan. 2015 to Feb. 2018 were analyzed retrospectively. All cases were treated with intravitreal ranibizumb injection(0.5 mg/0.05 ml)and panretinal photocoagulation at 1 week after injection. Results The IOP was(19.45±8.54)mmHg(1mmHg=0.133 kPa)at 3 months after treatment, which was significantly lower than that before treatment(41.80±9.84)mmHg(P=0.000). The visual acuity was improved significantly (P=0.000). The new vessels of iris and anterior chamber angle basically disappeared. There was no serious complication or adverse reactions in all patients. Conclusion Intravitreal ranibizunmb injection combined with panretinal photocoagulation for the treatment of neovascular glaucoma can significantly reduce the IOP and improve visual function of the patients without obvious adverse reactions. Key words: Glaucoma, neovascular; Ranibizumab; Injection, intravitreal; Photocoagulation, panretinal
目的观察雷尼单抗玻璃体内注射联合全视网膜光凝治疗新生血管性青光眼的疗效。方法回顾性分析2015年1月至2018年2月巴彦淖尔残疾人联合会眼科医院收治的20例新生血管性青光眼患者的20只眼。所有病例均给予玻璃体内注射雷尼单(0.5 mg/0.05 ml),注射后1周进行全视网膜光凝治疗。结果治疗后3个月IOP为(19.45±8.54)mmHg(1mmHg=0.133 kPa),显著低于治疗前(41.80±9.84)mmHg(P=0.000)。视力明显改善(P=0.000)。虹膜及前房角新生血管基本消失。所有患者均无严重并发症和不良反应。结论玻璃体内注射雷尼珠单抗联合全视网膜光凝治疗新生血管性青光眼可显著降低患者IOP,改善视功能,无明显不良反应。关键词:青光眼;新生血管;之初;注入,intravitreal;凝固,全
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引用次数: 0
期刊
中华眼外伤职业眼病杂志
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