Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.2095-1477.2020.02.010
Xiao-li Zhang, Lumin Zhang, Dan Liu
Objective To observe the efficacy of extraocular muscle adjustment suture operation under microscope in the treatment of complex strabismus. Methods A retrospective analysis. The clinical data of 191 patients with complex strabismus admitted to the Zhengzhou Second Hospital from Jan. 2015 to Dec. 2018 were analyzed. Under general anesthesia, all patients underwent strabismus correction with adjustable suture of extraocular muscles under microscope. Eighty-three patients underwent super-long recession. Ocular position and whether there was diplopia or whether diplopia disappeared were observed after recovery of general anesthesia or the next day. Suture was adjusted under local anesthesia or general anesthesia if necessary. The followed-up time was 6 months. Results After sugery all patients had good correction of ocular position, diplopia disappeared, and none of them had muscle slippage and other complication. Conclusion For complex strabismus, the strabismus correction with extraocular muscle adjustment suture operation under microscope can significantly increase the success rate of one-time operation and reduce the surgical response. Key words: Strabismus, complex; Surgery, adjustable suture, under microscope
{"title":"Efficacy of extraocular muscle adjustment suture operation under microscope in the treatment of complex strabismus","authors":"Xiao-li Zhang, Lumin Zhang, Dan Liu","doi":"10.3760/CMA.J.ISSN.2095-1477.2020.02.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2020.02.010","url":null,"abstract":"Objective \u0000To observe the efficacy of extraocular muscle adjustment suture operation under microscope in the treatment of complex strabismus. \u0000 \u0000 \u0000Methods \u0000A retrospective analysis. The clinical data of 191 patients with complex strabismus admitted to the Zhengzhou Second Hospital from Jan. 2015 to Dec. 2018 were analyzed. Under general anesthesia, all patients underwent strabismus correction with adjustable suture of extraocular muscles under microscope. Eighty-three patients underwent super-long recession. Ocular position and whether there was diplopia or whether diplopia disappeared were observed after recovery of general anesthesia or the next day. Suture was adjusted under local anesthesia or general anesthesia if necessary. The followed-up time was 6 months. \u0000 \u0000 \u0000Results \u0000After sugery all patients had good correction of ocular position, diplopia disappeared, and none of them had muscle slippage and other complication. \u0000 \u0000 \u0000Conclusion \u0000For complex strabismus, the strabismus correction with extraocular muscle adjustment suture operation under microscope can significantly increase the success rate of one-time operation and reduce the surgical response. \u0000 \u0000 \u0000Key words: \u0000Strabismus, complex; Surgery, adjustable suture, under microscope","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":"83 1","pages":"127-133"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79340603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.2095-1477.2020.02.004
Jingjing Wan, Yue Chen
Objective To compare the clinical efficacy between 577 nm micropulse laser and traditional laser retinal photocoagulation for the treatment of acute central serous chorioretinopathy (CSC). Methods Prospective clinical randomized controlled study.Fifty-four eyes of 45 cases diagnosed as acute CSC from Jul.2017 to Jun.2018 in the First Affiliated Hospital of Zhengzhou University were included in this study.Patients were randomly divided into two groups.Group A, 29 eyes of 23 cases, received 577 nm laser photocoagulation, and group B, 25 eyes of 22 cases, received traditional laser photocoagulation.The efficacy of the two groups were observed in followed up time. Results BCVA of two groups were improved at 1 and 3 months after treatment, and the difference was statistically significant between before and after treatment (P 0.05). In the last follow-up, the fundus examination and OCT showed no laser spot or damage of retinal pigment epithelium in group A, while 13 eyes (52.00%, 13/25) in the laser pigmentation change or slight pigment epithelial hyperplasia could be seen, and 6 eyes (24.00%, 6/25) on OCT local retinal pigment epithelial change or defect could be seen in group B. Conclusion Both 577 nm micropulse laser and traditional laser photocoagulation are effective for acute CSC, which can improve BCVA, reduce CMT and SRF.But the damage of 577 nm micropulse laser is slight. Key words: Chorioretinopathy, serous, central; Photocoagulation, laser; Efficacy
{"title":"Comparison of efficacy between 577 nm micropulse laser and traditional laser retinal photocoagulation for the treatment of acute central serous chorioretinopathy","authors":"Jingjing Wan, Yue Chen","doi":"10.3760/CMA.J.ISSN.2095-1477.2020.02.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2020.02.004","url":null,"abstract":"Objective \u0000To compare the clinical efficacy between 577 nm micropulse laser and traditional laser retinal photocoagulation for the treatment of acute central serous chorioretinopathy (CSC). \u0000 \u0000 \u0000Methods \u0000Prospective clinical randomized controlled study.Fifty-four eyes of 45 cases diagnosed as acute CSC from Jul.2017 to Jun.2018 in the First Affiliated Hospital of Zhengzhou University were included in this study.Patients were randomly divided into two groups.Group A, 29 eyes of 23 cases, received 577 nm laser photocoagulation, and group B, 25 eyes of 22 cases, received traditional laser photocoagulation.The efficacy of the two groups were observed in followed up time. \u0000 \u0000 \u0000Results \u0000BCVA of two groups were improved at 1 and 3 months after treatment, and the difference was statistically significant between before and after treatment (P 0.05). In the last follow-up, the fundus examination and OCT showed no laser spot or damage of retinal pigment epithelium in group A, while 13 eyes (52.00%, 13/25) in the laser pigmentation change or slight pigment epithelial hyperplasia could be seen, and 6 eyes (24.00%, 6/25) on OCT local retinal pigment epithelial change or defect could be seen in group B. \u0000 \u0000 \u0000Conclusion \u0000Both 577 nm micropulse laser and traditional laser photocoagulation are effective for acute CSC, which can improve BCVA, reduce CMT and SRF.But the damage of 577 nm micropulse laser is slight. \u0000 \u0000 \u0000Key words: \u0000Chorioretinopathy, serous, central; Photocoagulation, laser; Efficacy","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":"144 1","pages":"99-104"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84597365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.2095-1477.2020.02.005
S. Gu, Jian-wei Liu
Objective To analyze the clinical features and treatment of the ocular trauma caused by wood. Methods A total of 25 eyes of 25 cases with ocular trauma caused by wood from Aug. 2018 to Dec. 2018 in Affiliated Hospital of Weifang Medical University were retrospectively analyzed. Results There were 15 cases with closed ocular trauma, the complications included hyphema, lens injury and cyclodialysis cleft. There were 2 cases with 3 kinds of complications, 2 cases with 2 kinds of complications and 11 cases with only 1 kind of complication. All the 15 cases underwent lens surgery, and among them 4 cases received cilliary suture and 10 cases received vitrectomy combined with lens surgery. Among 10 cases with open ocular trauma, the range of injury in zone Ⅰ was 7 cases, 2 cases in zone Ⅱ and 1 case in zone Ⅲ. The 10 cases underwent one stage debridement and suturing, which combined with lens surgery in 4 cases, 2 cases with vitrectomy and 10 cases with vitrectomy and lens surgery. The difference was statistically significant between types of complications in group A and visual acuity impairment (P<0.05). The difference was statistically significant between locations of trauma and visual acuity impairment in group B (P<0.05). The difference in postoperative visual acuity was statistically significant between two groups. Conclusion With the increase of complications in closed ocular trauma, the visual impariment is obviously influenced. The range of injury is a significant factor affecting visual prognosis in open ocular trauma. The visual acuity of patient with injury in zoneⅠis better than that in zone Ⅱ and zoneⅢ. Open ocular trauma has a worse prognosis of visual acuity than that of closed ocular trauma. Key words: Trauma, ocular, wood; Severity, injury; Method, surgery
{"title":"The clinical analysis of the ocular trauma caused by wood","authors":"S. Gu, Jian-wei Liu","doi":"10.3760/CMA.J.ISSN.2095-1477.2020.02.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2020.02.005","url":null,"abstract":"Objective \u0000To analyze the clinical features and treatment of the ocular trauma caused by wood. \u0000 \u0000 \u0000Methods \u0000A total of 25 eyes of 25 cases with ocular trauma caused by wood from Aug. 2018 to Dec. 2018 in Affiliated Hospital of Weifang Medical University were retrospectively analyzed. \u0000 \u0000 \u0000Results \u0000There were 15 cases with closed ocular trauma, the complications included hyphema, lens injury and cyclodialysis cleft. There were 2 cases with 3 kinds of complications, 2 cases with 2 kinds of complications and 11 cases with only 1 kind of complication. All the 15 cases underwent lens surgery, and among them 4 cases received cilliary suture and 10 cases received vitrectomy combined with lens surgery. Among 10 cases with open ocular trauma, the range of injury in zone Ⅰ was 7 cases, 2 cases in zone Ⅱ and 1 case in zone Ⅲ. The 10 cases underwent one stage debridement and suturing, which combined with lens surgery in 4 cases, 2 cases with vitrectomy and 10 cases with vitrectomy and lens surgery. The difference was statistically significant between types of complications in group A and visual acuity impairment (P<0.05). The difference was statistically significant between locations of trauma and visual acuity impairment in group B (P<0.05). The difference in postoperative visual acuity was statistically significant between two groups. \u0000 \u0000 \u0000Conclusion \u0000With the increase of complications in closed ocular trauma, the visual impariment is obviously influenced. The range of injury is a significant factor affecting visual prognosis in open ocular trauma. The visual acuity of patient with injury in zoneⅠis better than that in zone Ⅱ and zoneⅢ. Open ocular trauma has a worse prognosis of visual acuity than that of closed ocular trauma. \u0000 \u0000 \u0000Key words: \u0000Trauma, ocular, wood; Severity, injury; Method, surgery","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":"68 1","pages":"105-108"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78254635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.2095-1477.2020.02.016
Ke Wang, Lijie Li, Yuying Wang
This paper briefly describes the management measures of ophthalmic out-patient department during the epidemic of COVID-19.The outpatient prevention and control managements should be carried out, including the aspects of appointment, pre-examination triage, zone management, treatment of emergency patients such as ocular trauma and health education. Meanwhile, the protection of medical staff should be strengthened, and the equipment should be strictly cleaned and disinfected.This article can provide new ideas and methods for ophthalmologists to avoid COVID-19 outbreak between doctors and patients and between patients during the epidemic of COVID-19. Key words: COVID-19; Trauma, ocular; Management, emergency, outpatient, ophthalmic
{"title":"Management practices of ophthalmology clinic for COVID-19","authors":"Ke Wang, Lijie Li, Yuying Wang","doi":"10.3760/CMA.J.ISSN.2095-1477.2020.02.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2020.02.016","url":null,"abstract":"This paper briefly describes the management measures of ophthalmic out-patient department during the epidemic of COVID-19.The outpatient prevention and control managements should be carried out, including the aspects of appointment, pre-examination triage, zone management, treatment of emergency patients such as ocular trauma and health education. Meanwhile, the protection of medical staff should be strengthened, and the equipment should be strictly cleaned and disinfected.This article can provide new ideas and methods for ophthalmologists to avoid COVID-19 outbreak between doctors and patients and between patients during the epidemic of COVID-19. \u0000 \u0000Key words: \u0000COVID-19; Trauma, ocular; Management, emergency, outpatient, ophthalmic","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":"1 1","pages":"156-160"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78346046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.2095-1477.2020.02.013
Zhiqi Chen, C. Deng, K. Ma, Junming Wang
At present, ophthalmologists should try their best to treat the COVID-19, and should do well in the diagnosis and treatment of ocular diseases. In order to help to finish the work more efficiently and safely, this paper analyzed the risk of ophthalmological diagnosis and treatment during the period of COVID-19 and put forward protective suggestions for reference. Key words: COVID-19; Ophthalmology; Protection
{"title":"Risk and protective analysis of ophthalmic diagnosis and treatment during the period of COVID-19","authors":"Zhiqi Chen, C. Deng, K. Ma, Junming Wang","doi":"10.3760/CMA.J.ISSN.2095-1477.2020.02.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2020.02.013","url":null,"abstract":"At present, ophthalmologists should try their best to treat the COVID-19, and should do well in the diagnosis and treatment of ocular diseases. In order to help to finish the work more efficiently and safely, this paper analyzed the risk of ophthalmological diagnosis and treatment during the period of COVID-19 and put forward protective suggestions for reference. \u0000 \u0000Key words: \u0000COVID-19; Ophthalmology; Protection","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":"39 1","pages":"143-147"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84990954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.2095-1477.2020.02.011
X. Tao, Jin Zhong, Linyong Chen
Objective To observe the effect of phacoemulsification on ocular surface function in cataract patients with Meibomian gland dysfunction (MGD). Methods A prospective cohort study. Total of 81 eyes of 78 cases of cataract with MGD in Wenrong Hospital of Jinhua from Mar.2016 to Feb.2018 were enrolled in this study.All patients underwent phacoemulsification and intraocular lens implantation.The ocular surface function was observed and all cases were followed up for 3 months. Results The Schirmer test (SIt) and break up time (BUT) at 3 days after operation were higher than those at 1 day before operation (P 0.05), and no significant difference between 3 days after operation and 3 months after operation (P>0.05), and the difference was significant between 1 day before operation and 3 months after operation (P<0.05). Conclusion After phacoemulsification, ocular dysfunction still occurs in patients with cataract and MGD.No significant recovery occurrs after 3 months of follow-up. Key words: Cataract; Disorder, function, Meibomian gland; Phacoemulsification; Function, ocular surface
目的观察超声乳化术对伴有睑板腺功能障碍(MGD)的白内障患者眼表功能的影响。方法前瞻性队列研究。选取金华市文荣医院2016年3月至2018年2月收治的78例白内障合并MGD患者的81只眼作为研究对象。所有患者均行超声乳化术和人工晶状体植入术。观察眼表功能，随访3个月。结果术后3 d的Schirmer试验(SIt)、破裂时间(BUT)均高于术前1 d (P<0.05)，术后3 d与术后3个月差异无统计学意义(P<0.05)，术后1 d与术后3个月差异有统计学意义(P<0.05)。结论白内障合并MGD患者行超声乳化术后仍存在眼功能障碍。随访3个月无明显恢复。关键词:白内障;紊乱，功能，睑板腺;超声乳化;功能、眼表
{"title":"The effect of phacoemulsification on ocular surface of cataract with Meibomian gland dysfunction","authors":"X. Tao, Jin Zhong, Linyong Chen","doi":"10.3760/CMA.J.ISSN.2095-1477.2020.02.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2020.02.011","url":null,"abstract":"Objective \u0000To observe the effect of phacoemulsification on ocular surface function in cataract patients with Meibomian gland dysfunction (MGD). \u0000 \u0000 \u0000Methods \u0000A prospective cohort study. Total of 81 eyes of 78 cases of cataract with MGD in Wenrong Hospital of Jinhua from Mar.2016 to Feb.2018 were enrolled in this study.All patients underwent phacoemulsification and intraocular lens implantation.The ocular surface function was observed and all cases were followed up for 3 months. \u0000 \u0000 \u0000Results \u0000The Schirmer test (SIt) and break up time (BUT) at 3 days after operation were higher than those at 1 day before operation (P 0.05), and no significant difference between 3 days after operation and 3 months after operation (P>0.05), and the difference was significant between 1 day before operation and 3 months after operation (P<0.05). \u0000 \u0000 \u0000Conclusion \u0000After phacoemulsification, ocular dysfunction still occurs in patients with cataract and MGD.No significant recovery occurrs after 3 months of follow-up. \u0000 \u0000 \u0000Key words: \u0000Cataract; Disorder, function, Meibomian gland; Phacoemulsification; Function, ocular surface","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":"14 1","pages":"134-137"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88401821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.2095-1477.2020.02.008
Yi Liu, Decheng Liu
Objective To evaluate the efficacy of posterior sub-tenon’s injection of triamcinolone acetonide in the treatment of optic disc vasculitis. Methods The clinical data of 60 eyes of 60 patients with optic disc vasculitis from May 2016 to May 2019 in the Seventh People’s Hospital of Zhengzhou were retrospectively analyzed. Triamcinolone acetonide 40 mg/0.5 ml was injected into Tenon’s capsule with a self-made gauge 6 lacrimal irrigation needle, and compound Xueshuantong and energy mixture were infused intravenously, compound anisodine injection was injected subcutaneously beside superficial temporal artery, methylcobalamin, citicoline and compound vitamin B were taken orally. All patients were followed up for 6-18 months. Results All 60 cases were cured within 6 to 18 months after treatment. The visual acuity were improved and the shape of macular fovea were restored, macular edema were alleviated. Conclusion Posterior sub-tenon’s injection of triamcinolone acetonide in the treatment of optic disc vasculitis is safe, effective, simple and inexpensive. Key words: Vasculitis, optic disc; Triamcinolone acetonide, injection, sub-tenon’s posterior; Efficacy, clinical
{"title":"Posterior sub-tenon’s injection of triamcinolone acetonide in the treatment of optic disc vasculitis","authors":"Yi Liu, Decheng Liu","doi":"10.3760/CMA.J.ISSN.2095-1477.2020.02.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2020.02.008","url":null,"abstract":"Objective \u0000To evaluate the efficacy of posterior sub-tenon’s injection of triamcinolone acetonide in the treatment of optic disc vasculitis. \u0000 \u0000 \u0000Methods \u0000The clinical data of 60 eyes of 60 patients with optic disc vasculitis from May 2016 to May 2019 in the Seventh People’s Hospital of Zhengzhou were retrospectively analyzed. Triamcinolone acetonide 40 mg/0.5 ml was injected into Tenon’s capsule with a self-made gauge 6 lacrimal irrigation needle, and compound Xueshuantong and energy mixture were infused intravenously, compound anisodine injection was injected subcutaneously beside superficial temporal artery, methylcobalamin, citicoline and compound vitamin B were taken orally. All patients were followed up for 6-18 months. \u0000 \u0000 \u0000Results \u0000All 60 cases were cured within 6 to 18 months after treatment. The visual acuity were improved and the shape of macular fovea were restored, macular edema were alleviated. \u0000 \u0000 \u0000Conclusion \u0000Posterior sub-tenon’s injection of triamcinolone acetonide in the treatment of optic disc vasculitis is safe, effective, simple and inexpensive. \u0000 \u0000 \u0000Key words: \u0000Vasculitis, optic disc; Triamcinolone acetonide, injection, sub-tenon’s posterior; Efficacy, clinical","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":"82 1","pages":"117-121"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74556338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.2095-1477.2020.02.006
Shuang Sun, Xiantao Sun, Yuebing Lu
Objective To evaluate the efficacy of intravitreal injection of different dose of conbercept for the treatment of retinopathy of prematurity (ROP). Methods Prospective randomized controlled study. The clinical data of 120 eyes of 60 children of prethreshold type 1 ROP diagnosed in Children’s Hospital Affiliated to Zhengzhou University from Oct. 2017 to Oct. 2018 were analyzed. All cases were randomly divided into two groups, including low-dose group (0.15 mg/0.015 ml) and high-dose group (0.25 mg/0.025 ml). The main outcome measure was the total success rate of treatment, and the secondary outcome measures were the success rate of single treatment and adverse reactions. Results The total success rate of treatment was 94.17% (113/120). In 52 eyes of 26 cases in the low-dose group, 49 eyes received one or more injections to control the disease, with a success rate of 94.23%. In 68 eyes of 34 children in the high-dose group, 64 eyes received one or more injections to control their condition, with a success rate of 94.12%. The difference was not statistically significant between the two groups (χ2=0.026, P=0.979). The success rate of single injection in low-dose group was 76.92% (40/52) and 61.76%(42/68) in the high-dose group. There is no statistically significant difference between the two groups (χ2=1.762, P=0.078). Conclusion The low-dose of conbercept is effective in the treatment of ROP, the care rate is the same as the high dose of that. Key words: Conbercept, injection, intravitreal, different doses; Retinopathy, premature; Success rate, treatment
{"title":"The efficacy among different dose of intravitreal conbercept injection for the treatment of retinopathy of prematurity","authors":"Shuang Sun, Xiantao Sun, Yuebing Lu","doi":"10.3760/CMA.J.ISSN.2095-1477.2020.02.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2020.02.006","url":null,"abstract":"Objective \u0000To evaluate the efficacy of intravitreal injection of different dose of conbercept for the treatment of retinopathy of prematurity (ROP). \u0000 \u0000 \u0000Methods \u0000Prospective randomized controlled study. The clinical data of 120 eyes of 60 children of prethreshold type 1 ROP diagnosed in Children’s Hospital Affiliated to Zhengzhou University from Oct. 2017 to Oct. 2018 were analyzed. All cases were randomly divided into two groups, including low-dose group (0.15 mg/0.015 ml) and high-dose group (0.25 mg/0.025 ml). The main outcome measure was the total success rate of treatment, and the secondary outcome measures were the success rate of single treatment and adverse reactions. \u0000 \u0000 \u0000Results \u0000The total success rate of treatment was 94.17% (113/120). In 52 eyes of 26 cases in the low-dose group, 49 eyes received one or more injections to control the disease, with a success rate of 94.23%. In 68 eyes of 34 children in the high-dose group, 64 eyes received one or more injections to control their condition, with a success rate of 94.12%. The difference was not statistically significant between the two groups (χ2=0.026, P=0.979). The success rate of single injection in low-dose group was 76.92% (40/52) and 61.76%(42/68) in the high-dose group. There is no statistically significant difference between the two groups (χ2=1.762, P=0.078). \u0000 \u0000 \u0000Conclusion \u0000The low-dose of conbercept is effective in the treatment of ROP, the care rate is the same as the high dose of that. \u0000 \u0000 \u0000Key words: \u0000Conbercept, injection, intravitreal, different doses; Retinopathy, premature; Success rate, treatment","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":"28 1","pages":"109-112"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87976730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-25DOI: 10.3760/CMA.J.ISSN.2095-1477.2020.01.003
Yuanyuan Zhang
Objective To observe the early efficacy of trabeculectomy combined with incision of outer wall of Schlemm’s canal in the treatment of juvenile glaucoma. Methods The clinical data of 34 eyes of 22 cases with juvenile glaucoma from Sep.2016 to Feb.2019 in the First Affiliated Hospital of Zhengzhou University were retrospectively analyzed.All patients underwent trabeculectomy combined with incision of outer wall of Schlemm’s canal.The followed-up times was 6 months. Results There was no significant difference in visual acuity (logMAR) between before and after operation (t=-0.544, P=0.590). The average IOP decreased at each time point postoperatively, and the difference was statistically significant between before and after operation (P<0.05). Functional filtration blebs were formed in 21 eyes (61.76%) postoperatively.The complete success was in 27 eyes (79.41%) at 6 months postoperatively, and the partial success was in 4 eyes (11.76%). The success rate was 91.17%(31/34). At 1 day postoperatively, the intraocular pressure was ≤21 mmHg in 34 eyes (1 mmHg=0.133 kPa). The intraocular pressure increased at 1 month postoperatively in 3 eyes.After treatment with ocular hypotensive drugs, IOP of them decreased to normal level.At 6 months postoperatively, the IOP increased in 7 eyes and decreased after treatment with ocular hypotensive drugs.There were 3 eyes with further visual field impairment and cup-to-disk ratio damage among 7 eyes.No serious complication during or after surgery occurred. Conclusion Trabeculectomy combined with incision of outer wall of Schlemm’s canal for the treatment of juvenile glaucoma can effectively control the IOP and protect visual function. Key words: Glaucoma, juvenile; Trabeculectomy; Incision, outer wall, Schlemm’s canal
{"title":"Observation on the early efficacy of trabeculectomy combined with incision of outer wall of Schlemm’s canal for the treatment of juvenile glaucoma","authors":"Yuanyuan Zhang","doi":"10.3760/CMA.J.ISSN.2095-1477.2020.01.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2020.01.003","url":null,"abstract":"Objective \u0000To observe the early efficacy of trabeculectomy combined with incision of outer wall of Schlemm’s canal in the treatment of juvenile glaucoma. \u0000 \u0000 \u0000Methods \u0000The clinical data of 34 eyes of 22 cases with juvenile glaucoma from Sep.2016 to Feb.2019 in the First Affiliated Hospital of Zhengzhou University were retrospectively analyzed.All patients underwent trabeculectomy combined with incision of outer wall of Schlemm’s canal.The followed-up times was 6 months. \u0000 \u0000 \u0000Results \u0000There was no significant difference in visual acuity (logMAR) between before and after operation (t=-0.544, P=0.590). The average IOP decreased at each time point postoperatively, and the difference was statistically significant between before and after operation (P<0.05). Functional filtration blebs were formed in 21 eyes (61.76%) postoperatively.The complete success was in 27 eyes (79.41%) at 6 months postoperatively, and the partial success was in 4 eyes (11.76%). The success rate was 91.17%(31/34). At 1 day postoperatively, the intraocular pressure was ≤21 mmHg in 34 eyes (1 mmHg=0.133 kPa). The intraocular pressure increased at 1 month postoperatively in 3 eyes.After treatment with ocular hypotensive drugs, IOP of them decreased to normal level.At 6 months postoperatively, the IOP increased in 7 eyes and decreased after treatment with ocular hypotensive drugs.There were 3 eyes with further visual field impairment and cup-to-disk ratio damage among 7 eyes.No serious complication during or after surgery occurred. \u0000 \u0000 \u0000Conclusion \u0000Trabeculectomy combined with incision of outer wall of Schlemm’s canal for the treatment of juvenile glaucoma can effectively control the IOP and protect visual function. \u0000 \u0000 \u0000Key words: \u0000Glaucoma, juvenile; Trabeculectomy; Incision, outer wall, Schlemm’s canal","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":"70 1","pages":"12-16"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77007993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-25DOI: 10.3760/CMA.J.ISSN.2095-1477.2020.01.012
Yunjuan Su
Objective To observe the change of corneal microstructural of patients with ocular surface squamous neoplasia (OSSN) after treatment with topical interferon alfa-2b (IFNα-2b) and 5-fluorouracil(5-FU). Methods A retrospective case series study.Total of 16 eyes of 16 patients with OSSN were treated with topical IFNα-2b (1 million IU/mL) and 1% 5-FU four times a day.The inneoplastic lesion and the cornea under involved areas were observed with in vivo confocal microscopy (IVCM) before and after treatment. Results Main features of OSSN at 4 months after treatment showed reduction reflectivity of epithelial cells, loss of cellular pleomorphism and demarcation line between normal and neoplastic tissue. Basal cell layers containing bright dots were found to diminish or disappear gradually. Other change was the reappearance of distinctsubbasal nerves. A few dendritic cells appeared as bright cellular particles with small dendritic processes that transformed into large and highly reflective arborizing cells were found. Conclusion The reduced reflectivity and polymorphhism of epithelial cells, and the increasing density of limbal dendritic cells after topical IFNα-2b and 5-FU therapy are observed with IVCM. Key words: Neoplasia, squamous, ocular surface; Cell, dendritic; Microscopy, in vivo, confocal
{"title":"The change of corneal microstructural of patients with ocular surface squamous neoplasia after treatment with topical interferon alfa-2b and 5-fluorouracil","authors":"Yunjuan Su","doi":"10.3760/CMA.J.ISSN.2095-1477.2020.01.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2020.01.012","url":null,"abstract":"Objective \u0000To observe the change of corneal microstructural of patients with ocular surface squamous neoplasia (OSSN) after treatment with topical interferon alfa-2b (IFNα-2b) and 5-fluorouracil(5-FU). \u0000 \u0000 \u0000Methods \u0000A retrospective case series study.Total of 16 eyes of 16 patients with OSSN were treated with topical IFNα-2b (1 million IU/mL) and 1% 5-FU four times a day.The inneoplastic lesion and the cornea under involved areas were observed with in vivo confocal microscopy (IVCM) before and after treatment. \u0000 \u0000 \u0000Results \u0000Main features of OSSN at 4 months after treatment showed reduction reflectivity of epithelial cells, loss of cellular pleomorphism and demarcation line between normal and neoplastic tissue. Basal cell layers containing bright dots were found to diminish or disappear gradually. Other change was the reappearance of distinctsubbasal nerves. A few dendritic cells appeared as bright cellular particles with small dendritic processes that transformed into large and highly reflective arborizing cells were found. \u0000 \u0000 \u0000Conclusion \u0000The reduced reflectivity and polymorphhism of epithelial cells, and the increasing density of limbal dendritic cells after topical IFNα-2b and 5-FU therapy are observed with IVCM. \u0000 \u0000 \u0000Key words: \u0000Neoplasia, squamous, ocular surface; Cell, dendritic; Microscopy, in vivo, confocal","PeriodicalId":10126,"journal":{"name":"Chinese Journal of Ocular Trauma and Occupational Eye Disease","volume":"25 1","pages":"54-59"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81571322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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