Objective: To survey the effectiveness of low vision aids (LVAs) in improveing quality of life for low vision patients. Methods: This was a prespective clinical study. Fifty-five patients with a clinical diagnosis of low vision who were required to wear far and near LVDs were selected from Eye Hospital, Wenzhou Medical University from January 2017 to February 2018 in this prospective clinical study. The low vision quality of life (LVQOL) questionnaire measured vision-related quality of life to evaluate the quality of the patients before 30 days after use of LVAs. Responses covered mobility, distance vision, lighting, psychological adjustment, reading, working ability and daily living ability. The LVQOL scores and related parameters of each group were statistically analyzed using t test and regression test. Results: Forty-four low vision patients completed the baseline and follow-up LVQOL surveys. After using the LVDs, the quality of life scores in the low vision patients increased significantly from 77.8±19.0 to 82.3±22.5 (t=4.56, P=0.001). Factors such as gender, literacy rate, learning status and vision did not affect the quality of life of patients with low vision. Conclusions: LVAs can improve the quality of life in a low vision population, regardless of age, gender or education level. Key words: low vision; low vision aids; questionnaire; low vision quality of life
{"title":"Low Vision Aids to Improve the Quality of Life in Low Vision Patients","authors":"Changsen Tu, Lingzhi Ni, Longfei Jiang, Xue-mei Zhang","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.06.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.06.010","url":null,"abstract":"Objective: \u0000To survey the effectiveness of low vision aids (LVAs) in improveing quality of life for low vision patients. \u0000 \u0000 \u0000Methods: \u0000This was a prespective clinical study. Fifty-five patients with a clinical diagnosis of low vision who were required to wear far and near LVDs were selected from Eye Hospital, Wenzhou Medical University from January 2017 to February 2018 in this prospective clinical study. The low vision quality of life (LVQOL) questionnaire measured vision-related quality of life to evaluate the quality of the patients before 30 days after use of LVAs. Responses covered mobility, distance vision, lighting, psychological adjustment, reading, working ability and daily living ability. The LVQOL scores and related parameters of each group were statistically analyzed using t test and regression test. \u0000 \u0000 \u0000Results: \u0000Forty-four low vision patients completed the baseline and follow-up LVQOL surveys. After using the LVDs, the quality of life scores in the low vision patients increased significantly from 77.8±19.0 to 82.3±22.5 (t=4.56, P=0.001). Factors such as gender, literacy rate, learning status and vision did not affect the quality of life of patients with low vision. \u0000 \u0000 \u0000Conclusions: \u0000LVAs can improve the quality of life in a low vision population, regardless of age, gender or education level. \u0000 \u0000 \u0000Key words: \u0000low vision; low vision aids; questionnaire; low vision quality of life","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"24 1","pages":"460-463"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76214900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2019.06.005
Jing-Tao Wang, Jiang Bian, Xin Wang, W. Shi, Suxia Li
Objective: To assess the impact of the pre-diagnostic use of corticosteroid on the prognosis of visual outcomes and treatment methods of fungal keratitis. Methods: This was a retrospective consecutive case cohort study. Two hundred and eleven eyes of 211 patients diagnosed with fungal keratitis from December 2014 to December 2015 in Shandong Eye Hospital were analyzed. Thirty-six eyes of 36 patients with a history of corticosteroid use before the diagnosis was the corticosteroid group. The remaining 175 eyes of 175 patients with no use of corticosteroid before or during the treatment was the control group. Patients' demographics, clinical findings, management details, changes after the antifungal therapy, and corrected distance visual acuity 2 months after the cure were recorded. Independent samples t test and chi-square test were used for statistical analysis. Results: The demographic data were matched between the two groups. The fungal onset time of the corticosteroid group was 14.5±10.1 days, which was significantly shorter than that of the control group, 20.6±22.5 days (t=2.657, P=0.008). The mean diameter of corneal lesions was 6.3±2.4 mm in the corticosteroid group, which was significantly larger than that of the control group 4.8±2.1 mm (t=3.683, P<0.001). The positive rate of a corneal scrape was 97.2% in the corticosteroid group and 90.6% in the control group, with no significant difference between the groups (χ2=1.633, P=0.201). Only 1 case (2.8%) in the corticosteroid group was cured by antifungal drugs, which was significantly lower than that of the control group, with 34 cases (19.4%) (χ2=5.983, P=0.014). Penetrating keratoplasty was performed in 22 cases (61.1%) in the corticosteroid group, a proportion that was significantly higher than that in the control group, with 55 cases (31.4%) (χ2=11.351, P=0.001). A corrected distance visual acuity of less than 0.3 after antifungal therapy was recorded in 32 cases (88.9%) in the corticosteroid group, a proportion which was significantly higher than in the control group, 110 cases (62.8%) (χ2=9.194, P=0.002). Conclusions: Corticosteroid use before a diagnosis of fungal keratitis can increase the range of lesions, while antifungal drugs seem to be less effective, which increases the probability of penetrating keratoplasty and a poorer outcome. Key words: corticosteroid; fungal keratitis; prognosis
{"title":"The Impact of Corticosteroid Use on the Prognosis of Fungal Keratitis","authors":"Jing-Tao Wang, Jiang Bian, Xin Wang, W. Shi, Suxia Li","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.06.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.06.005","url":null,"abstract":"Objective: \u0000To assess the impact of the pre-diagnostic use of corticosteroid on the prognosis of visual outcomes and treatment methods of fungal keratitis. \u0000 \u0000 \u0000Methods: \u0000This was a retrospective consecutive case cohort study. Two hundred and eleven eyes of 211 patients diagnosed with fungal keratitis from December 2014 to December 2015 in Shandong Eye Hospital were analyzed. Thirty-six eyes of 36 patients with a history of corticosteroid use before the diagnosis was the corticosteroid group. The remaining 175 eyes of 175 patients with no use of corticosteroid before or during the treatment was the control group. Patients' demographics, clinical findings, management details, changes after the antifungal therapy, and corrected distance visual acuity 2 months after the cure were recorded. Independent samples t test and chi-square test were used for statistical analysis. \u0000 \u0000 \u0000Results: \u0000The demographic data were matched between the two groups. The fungal onset time of the corticosteroid group was 14.5±10.1 days, which was significantly shorter than that of the control group, 20.6±22.5 days (t=2.657, P=0.008). The mean diameter of corneal lesions was 6.3±2.4 mm in the corticosteroid group, which was significantly larger than that of the control group 4.8±2.1 mm (t=3.683, P<0.001). The positive rate of a corneal scrape was 97.2% in the corticosteroid group and 90.6% in the control group, with no significant difference between the groups (χ2=1.633, P=0.201). Only 1 case (2.8%) in the corticosteroid group was cured by antifungal drugs, which was significantly lower than that of the control group, with 34 cases (19.4%) (χ2=5.983, P=0.014). Penetrating keratoplasty was performed in 22 cases (61.1%) in the corticosteroid group, a proportion that was significantly higher than that in the control group, with 55 cases (31.4%) (χ2=11.351, P=0.001). A corrected distance visual acuity of less than 0.3 after antifungal therapy was recorded in 32 cases (88.9%) in the corticosteroid group, a proportion which was significantly higher than in the control group, 110 cases (62.8%) (χ2=9.194, P=0.002). \u0000 \u0000 \u0000Conclusions: \u0000Corticosteroid use before a diagnosis of fungal keratitis can increase the range of lesions, while antifungal drugs seem to be less effective, which increases the probability of penetrating keratoplasty and a poorer outcome. \u0000 \u0000 \u0000Key words: \u0000corticosteroid; fungal keratitis; prognosis","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"2 1","pages":"426-432"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88525690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2019.06.008
Zhan-jun Lu, R. Ma, Qin Xiao, Chun-ming Tao, Yu-ling Bai, Eerdun Wang
Objective: To evaluate the clinical effects of Ming Mu-11 (MM-11) in the treatment of stage Ⅰ diabetic retinopathy (DR). Methods: One hundred twenty patients (120 eyes) with stage Ⅰ DR in the Affiliated Hospital of Inner Mongolia University for the Nationalities were selected from July 2016 to March 2017. The 120 eyes with stage Ⅰ DR were divided into two groups: a Mongolian medicine group and a control group (60 eyes each). The control group was treated with calcium dobesilate capsules and the Mongolian medicine group was also treated with MM-11 pills. There were three courses of treatment in total and 28 days in each course. Patients in both groups underwent multifocal electroretinogram (mfERG) and ultra-wide angle fundus photography examinations before and after the treatment. The latencies and amplitudes of the N1 wave and P1 wave were recorded as well as the number of retinal microaneurysms and hemorrhagic spots. Data were analyzed by t-test and Chi-square test. Results: The results of mfERG were as follows. There were significant differences in the amplitude density values of P1 in the R1-R5 regions before and after treatment (tcontrol group=66.86, 18.05, 36.33, 47.43, 30.56, P<0.001; tmongolian medicine group=31.52, 54.56, 101.98, 127.02, 45.74, P<0.001). There were significant differences in the amplitude density value of N1 in the R1-R5 regions before and after treatment (tcontrol group=70.18, 47.02, 78.08, 57.44, 64.51, P<0.001; tmongolian medicine group=46.09, 140.47, 145.14, 50.46, 73.94, P<0.001). Compared to the control group, the amplitude density value differences in the R1-R5 P1 and R1-R3 N1 regions in the Mongolian medicine group were significantly different before and after treatment (tP1=8.96, 23.96, 25.10, 28.80, 13.67, P<0.001; tN1=9.38, 30.34, 52.06, P<0.001). However, there was no significant difference in the amplitude density value in the R4-R5 N1 regions. There was no significant difference in the latency of P1 in the R1-R5 regions before and after treatment. There was no significant difference in the latency of N1 in the R1-R5 regions before and after treatment. The results of fundus color photography were as follows. The difference in microaneurysms and number of bleeding points before and after treatment were statistically significant in the Mongolian medicine group (t=2.08, P=0.042; t=2.07, P=0.043). The effective rates of the eye fundus photography in the Mongolian medicine group and the control group were 88% and 73%, respectively, which were analyzed by a chi-square test. The difference was statistically significant (χ2=4.36, P=0.037). Conclusions: MM-11 is very effective for treating the damage of retinal functions in stage Ⅰ DR and therefore can be considered as a drug for routine use. Key words: Mongolian medicine Ming Mu-11 Pills; multifocal electroretinogram; diabetic retinopathy; ultra-wideangle fundus photography
{"title":"Effects of the Mongolian Medicine Ming Mu-11 on Retinal Functions in Stage I Diabetic Retinopathy","authors":"Zhan-jun Lu, R. Ma, Qin Xiao, Chun-ming Tao, Yu-ling Bai, Eerdun Wang","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.06.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.06.008","url":null,"abstract":"Objective: \u0000To evaluate the clinical effects of Ming Mu-11 (MM-11) in the treatment of stage Ⅰ diabetic retinopathy (DR). \u0000 \u0000 \u0000Methods: \u0000One hundred twenty patients (120 eyes) with stage Ⅰ DR in the Affiliated Hospital of Inner Mongolia University for the Nationalities were selected from July 2016 to March 2017. The 120 eyes with stage Ⅰ DR were divided into two groups: a Mongolian medicine group and a control group (60 eyes each). The control group was treated with calcium dobesilate capsules and the Mongolian medicine group was also treated with MM-11 pills. There were three courses of treatment in total and 28 days in each course. Patients in both groups underwent multifocal electroretinogram (mfERG) and ultra-wide angle fundus photography examinations before and after the treatment. The latencies and amplitudes of the N1 wave and P1 wave were recorded as well as the number of retinal microaneurysms and hemorrhagic spots. Data were analyzed by t-test and Chi-square test. \u0000 \u0000 \u0000Results: \u0000The results of mfERG were as follows. There were significant differences in the amplitude density values of P1 in the R1-R5 regions before and after treatment (tcontrol group=66.86, 18.05, 36.33, 47.43, 30.56, P<0.001; tmongolian medicine group=31.52, 54.56, 101.98, 127.02, 45.74, P<0.001). There were significant differences in the amplitude density value of N1 in the R1-R5 regions before and after treatment (tcontrol group=70.18, 47.02, 78.08, 57.44, 64.51, P<0.001; tmongolian medicine group=46.09, 140.47, 145.14, 50.46, 73.94, P<0.001). Compared to the control group, the amplitude density value differences in the R1-R5 P1 and R1-R3 N1 regions in the Mongolian medicine group were significantly different before and after treatment (tP1=8.96, 23.96, 25.10, 28.80, 13.67, P<0.001; tN1=9.38, 30.34, 52.06, P<0.001). However, there was no significant difference in the amplitude density value in the R4-R5 N1 regions. There was no significant difference in the latency of P1 in the R1-R5 regions before and after treatment. There was no significant difference in the latency of N1 in the R1-R5 regions before and after treatment. The results of fundus color photography were as follows. The difference in microaneurysms and number of bleeding points before and after treatment were statistically significant in the Mongolian medicine group (t=2.08, P=0.042; t=2.07, P=0.043). The effective rates of the eye fundus photography in the Mongolian medicine group and the control group were 88% and 73%, respectively, which were analyzed by a chi-square test. The difference was statistically significant (χ2=4.36, P=0.037). \u0000 \u0000 \u0000Conclusions: \u0000MM-11 is very effective for treating the damage of retinal functions in stage Ⅰ DR and therefore can be considered as a drug for routine use. \u0000 \u0000 \u0000Key words: \u0000Mongolian medicine Ming Mu-11 Pills; multifocal electroretinogram; diabetic retinopathy; ultra-wideangle fundus photography","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"39 1","pages":"444-450"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85589458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To investigate the visual and refractive outcomes in patients with super high myopia after thin-flap femtosecond laser assisted LASIK (FS-LASIK) combined Triple-A profile. Methods: In this prospective non-randomized case-controlled study, patients were enrolled from January to July 2016 at Affiliated Hospital of Nanjing University of Chinese Medicine, were divided into high myopia group (96 eyes of 48 patients) and super high myopia group (88 eyes of 44 patients). All patients were treated with FS-LASIK combined Triple-A profile. Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), spherical equivalent (SE) and high order aberration were measured preoperatively and 1 day, 1 week, and 1, 3 and 6 months postoperatively. Data were analyzed using repeated measurs ANOVA and generalized estimating equation. Results: At 1, 3 and 6 months after surgery, there was no significant difference between the two groups in the ratio of UCVA that was better than or equal to preoperative BCVA (P>0.05). At postoperative 6 months, there was no significant difference in the efficacy and safety index between the two groups (P>0.05). There was a hyperopic shift in the two groups after surgery. The shift was more significant in the super high myopia group in the early stage after surgery. The SE of the two groups tended to be stable after 3 months postoperatively. The changes in total corneal high order aberrations, spherical aberration and horizontal coma were significantly different in time and group, but there was no significant difference in vertical corneal aberration. Conclusions: The postoperative results indicate that using the Triple-A ablation profile of the MEL 90 excimer laser associated with thin-flaps is a safe, efficient, and predictable method to correct super high myopia. Key words: thin-flap; femtosecond laser; laser in situ keratomileusis; super high myopia; triple-A; visual quality
{"title":"Clinical Study of FS-LASIK with the Triple-A Profile for Super High Myopia Correction","authors":"Jing Wu, Chuan-wei Zhang, Yi-Shuo Yao, Xuejuan Wu, haiyan Huang","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.06.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.06.004","url":null,"abstract":"Objective: \u0000To investigate the visual and refractive outcomes in patients with super high myopia after thin-flap femtosecond laser assisted LASIK (FS-LASIK) combined Triple-A profile. \u0000 \u0000 \u0000Methods: \u0000In this prospective non-randomized case-controlled study, patients were enrolled from January to July 2016 at Affiliated Hospital of Nanjing University of Chinese Medicine, were divided into high myopia group (96 eyes of 48 patients) and super high myopia group (88 eyes of 44 patients). All patients were treated with FS-LASIK combined Triple-A profile. Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), spherical equivalent (SE) and high order aberration were measured preoperatively and 1 day, 1 week, and 1, 3 and 6 months postoperatively. Data were analyzed using repeated measurs ANOVA and generalized estimating equation. \u0000 \u0000 \u0000Results: \u0000At 1, 3 and 6 months after surgery, there was no significant difference between the two groups in the ratio of UCVA that was better than or equal to preoperative BCVA (P>0.05). At postoperative 6 months, there was no significant difference in the efficacy and safety index between the two groups (P>0.05). There was a hyperopic shift in the two groups after surgery. The shift was more significant in the super high myopia group in the early stage after surgery. The SE of the two groups tended to be stable after 3 months postoperatively. The changes in total corneal high order aberrations, spherical aberration and horizontal coma were significantly different in time and group, but there was no significant difference in vertical corneal aberration. \u0000 \u0000 \u0000Conclusions: \u0000The postoperative results indicate that using the Triple-A ablation profile of the MEL 90 excimer laser associated with thin-flaps is a safe, efficient, and predictable method to correct super high myopia. \u0000 \u0000 \u0000Key words: \u0000thin-flap; femtosecond laser; laser in situ keratomileusis; super high myopia; triple-A; visual quality","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"11 1","pages":"420-425"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76420306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To compare visual performance after bilateral implantation of a bifocal (ReSTOR +3.0 D) or trifocal (AT Lisa tri. 839MP) intraocular lens (IOL). Methods: This prospective clinical study involved patients who had cataract surgery that included the bilateral implantation of a bifocal or trifocal IOL from April 2017 to May 2018 at Wuhan Aier Eye Hospital. Fifty-two eyes (26 patients) were implanted with a trifocal IOL (AT Lisa tri. 839MP) as trifocal group and fifty-two eyes (26 patients) with a bifocal IOL (ReSTOR +3.0 D) as bifocal IOL group. The follow-up was 3 months. Near, intermediate, and distance visual acuities, defocus curve, optical quality, including modulation transfer functions and intraocular aberrations, ocular aberrations with 3 mm and 5 mm pupil diameters, National Eye Institute Visual Functioning Questionnaire-14 for Chinese people (VF-14-CN), spectacle independence and patient satisfaction were assessed in all patients. Data were assessed with a Student's t test, Mann-Whitney U test, and Chi-square test. Results: No statistically significant difference was found in distance, near, best corrected distance, distance-corrected intermediate, or distance-corrected near visual acuity between the two groups. Uncorrected intermediate visual acuity was significantly better in the trifocal IOL group (Z=-2.347, P=0.019). In the binocular defocus curve, visual acuity was also significantly better for defocus at -1.0, -3.0, 3.5 and 4.0 diopters (Z=-2.619, -2.452, -2.452, -2.147; P=0.009, 0.014, 0.014, 0.032). No significant difference was found between the two groups for mean postoperative contrast sensitivity function under photopic conditions with or without glare. With a 3 mm or 5 mm pupil diameter, intraocular higher-order aberrations, coma, trefoil and total higher-order aberrations, and trefoil aberrations were significantly lower in the trifocal IOL group (P<0.05). With a 5 mm pupil diameter, intraocular spherical aberrations were significantly lower in the trifocal IOL group (Z=-3.053, P=0.002), but no statistically significant difference was found in modulation transfer function at 3 mm and 5 mm pupil diameters between the two groups. The level of overall satisfaction was similarly high for both groups. Conclusions: Trifocal IOLs can provide significantly better intermediate vision and equivalent distance and near visual performance compared to bifocal IOLs and have the same level of overall satisfaction. Key words: trifocal intraocular lens; defocus curve; contrast sensitivity; aberration; visual quality; optical quality
{"title":"Comparison of the Early Visual Performance after Bilateral Implantation of Trifocal and Bifocal Intraocular Lenses","authors":"Bichao Chen, Qian Tan, Xiao Wang, Xueting Li, Danmin Cao, Yong Wang","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.06.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.06.009","url":null,"abstract":"Objective: \u0000To compare visual performance after bilateral implantation of a bifocal (ReSTOR +3.0 D) or trifocal (AT Lisa tri. 839MP) intraocular lens (IOL). \u0000 \u0000 \u0000Methods: \u0000This prospective clinical study involved patients who had cataract surgery that included the bilateral implantation of a bifocal or trifocal IOL from April 2017 to May 2018 at Wuhan Aier Eye Hospital. Fifty-two eyes (26 patients) were implanted with a trifocal IOL (AT Lisa tri. 839MP) as trifocal group and fifty-two eyes (26 patients) with a bifocal IOL (ReSTOR +3.0 D) as bifocal IOL group. The follow-up was 3 months. Near, intermediate, and distance visual acuities, defocus curve, optical quality, including modulation transfer functions and intraocular aberrations, ocular aberrations with 3 mm and 5 mm pupil diameters, National Eye Institute Visual Functioning Questionnaire-14 for Chinese people (VF-14-CN), spectacle independence and patient satisfaction were assessed in all patients. Data were assessed with a Student's t test, Mann-Whitney U test, and Chi-square test. \u0000 \u0000 \u0000Results: \u0000No statistically significant difference was found in distance, near, best corrected distance, distance-corrected intermediate, or distance-corrected near visual acuity between the two groups. Uncorrected intermediate visual acuity was significantly better in the trifocal IOL group (Z=-2.347, P=0.019). In the binocular defocus curve, visual acuity was also significantly better for defocus at -1.0, -3.0, 3.5 and 4.0 diopters (Z=-2.619, -2.452, -2.452, -2.147; P=0.009, 0.014, 0.014, 0.032). No significant difference was found between the two groups for mean postoperative contrast sensitivity function under photopic conditions with or without glare. With a 3 mm or 5 mm pupil diameter, intraocular higher-order aberrations, coma, trefoil and total higher-order aberrations, and trefoil aberrations were significantly lower in the trifocal IOL group (P<0.05). With a 5 mm pupil diameter, intraocular spherical aberrations were significantly lower in the trifocal IOL group (Z=-3.053, P=0.002), but no statistically significant difference was found in modulation transfer function at 3 mm and 5 mm pupil diameters between the two groups. The level of overall satisfaction was similarly high for both groups. \u0000 \u0000 \u0000Conclusions: \u0000Trifocal IOLs can provide significantly better intermediate vision and equivalent distance and near visual performance compared to bifocal IOLs and have the same level of overall satisfaction. \u0000 \u0000 \u0000Key words: \u0000trifocal intraocular lens; defocus curve; contrast sensitivity; aberration; visual quality; optical quality","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"33 1","pages":"451-459"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91387019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2019.06.012
Shasha Luo
{"title":"A Case of Internal Limiting Membrane Packing in Optic Disc Pit","authors":"Shasha Luo","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.06.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.06.012","url":null,"abstract":"","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"67 1","pages":"470-473"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75043031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2019.06.007
J. Tao, Huan Chen, Lijun Shen, Xueting Yu, Yiqi Chen, J. Mao
Objective: To evaluate the effect of vitrectomy and internal limiting membrane peeling with air tamponade for the treatment of idiopathic macular hole (MH). Methods: A retrospective study was performed on 32 eyes of 32 patients with idiopathic macular hole in our hospital from January 2017 to January 2018. There were 9 males (9 eyes) and 23 females (23 eyes), with amean age of 60.7±12.2 years (range from 47~78 years). Pars plana vitrectomy with internal limiting membrane peeling was performed, followed by fluid-air exchange. According to the results of OCT scanning in the first postoperative follow-up, all patients were divided into two groups: MH closed ornot closed. The preoperative and postoperative best corrected visual acuity (BCVA) and diameter of the MH were compared between the two groups, using a Wilcoxon test and independent sample t test. The MH closure rate, the continuity of the external limiting membranes and photoreceptors were compared using a chi square test. Results: At the last follow-up, the LogMAR BCVA was 0.40 (0.30, 0.73), which was significantly higher than the preoperative BCVA 0.80 (0.70, 1.00) (Z=-3.439, P<0.001). Early postoperative OCT scansshowed that 24 macular holeswere closed, while the macular holes in the other 8 eyes were not closed sofluid-air exchange was performed again. The macular holeswereclosed in all 8 patients one month after the second treatment or the last follow-up. Sixteen patients hadcontinuous external limiting membrane (ELM) but none with a continuous external zone (EZ) in the OCT scansone month after the operation. However, 18 patients showed continuous ELM and 6 showed continuous EZ at the last follow-up. According to whether MH was closed or not at the first postoperative OCT scanning, all patients were divided into two groups. The mean pre-surgical diameter of the MH of the unclosed group was 532±104 um, which was significantly larger than that of the closed group (352±180 μm) (t=-2.656, P=0.013). The continuity of the ELM of the MH closed group was higher than the unclosed group at one month after the operation and at the last follow-up (P<0.05). The patients with continuous EZ at the last follow-up were all in the closed group, while the EZs in the unclosed group were discontinuous. There was a statistically significant difference between the two groups (χ2=3.89, P=0.048). Conclusions: The results of this study indicate that vitrectomy combined with ILM peeling and air tamponade for the treatment of idiopathic macular hole has a good result. However, for those macular holes with more than a 400 um diameter, a second fluid-air exchange is needed. Early closure of the MH suggests a better prognosis after surgery. Key words: macular hole; air tamponade; vitrectomy
{"title":"Clinical Outcomes of Vitrectomy and Internal Limiting Membrane Peeling with Air Tamponade for the Treatment of Idiopathic Macular Hole","authors":"J. Tao, Huan Chen, Lijun Shen, Xueting Yu, Yiqi Chen, J. Mao","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.06.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.06.007","url":null,"abstract":"Objective: \u0000To evaluate the effect of vitrectomy and internal limiting membrane peeling with air tamponade for the treatment of idiopathic macular hole (MH). \u0000 \u0000 \u0000Methods: \u0000A retrospective study was performed on 32 eyes of 32 patients with idiopathic macular hole in our hospital from January 2017 to January 2018. There were 9 males (9 eyes) and 23 females (23 eyes), with amean age of 60.7±12.2 years (range from 47~78 years). Pars plana vitrectomy with internal limiting membrane peeling was performed, followed by fluid-air exchange. According to the results of OCT scanning in the first postoperative follow-up, all patients were divided into two groups: MH closed ornot closed. The preoperative and postoperative best corrected visual acuity (BCVA) and diameter of the MH were compared between the two groups, using a Wilcoxon test and independent sample t test. The MH closure rate, the continuity of the external limiting membranes and photoreceptors were compared using a chi square test. \u0000 \u0000 \u0000Results: \u0000At the last follow-up, the LogMAR BCVA was 0.40 (0.30, 0.73), which was significantly higher than the preoperative BCVA 0.80 (0.70, 1.00) (Z=-3.439, P<0.001). Early postoperative OCT scansshowed that 24 macular holeswere closed, while the macular holes in the other 8 eyes were not closed sofluid-air exchange was performed again. The macular holeswereclosed in all 8 patients one month after the second treatment or the last follow-up. Sixteen patients hadcontinuous external limiting membrane (ELM) but none with a continuous external zone (EZ) in the OCT scansone month after the operation. However, 18 patients showed continuous ELM and 6 showed continuous EZ at the last follow-up. According to whether MH was closed or not at the first postoperative OCT scanning, all patients were divided into two groups. The mean pre-surgical diameter of the MH of the unclosed group was 532±104 um, which was significantly larger than that of the closed group (352±180 μm) (t=-2.656, P=0.013). The continuity of the ELM of the MH closed group was higher than the unclosed group at one month after the operation and at the last follow-up (P<0.05). The patients with continuous EZ at the last follow-up were all in the closed group, while the EZs in the unclosed group were discontinuous. There was a statistically significant difference between the two groups (χ2=3.89, P=0.048). \u0000 \u0000 \u0000Conclusions: \u0000The results of this study indicate that vitrectomy combined with ILM peeling and air tamponade for the treatment of idiopathic macular hole has a good result. However, for those macular holes with more than a 400 um diameter, a second fluid-air exchange is needed. Early closure of the MH suggests a better prognosis after surgery. \u0000 \u0000 \u0000Key words: \u0000macular hole; air tamponade; vitrectomy","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"34 1","pages":"439-443"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88478411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To compare dry eye characteristics in eyes after femtosecond laser-assisted in situ keratomileusis (FS-LASIK) or off-flap laser epithelial keratomileusis (LASEK). Methods: Thirty eyes of 30 patients with myopia who had FS-LASIK (FS-LASIK group) and 30 eyes of 30 patients with myopia who had off-flap LASEK (LASEK group) at the Refractive Surgery Center of the Ningbo Eye Hospital from August 2016 to February 2017 were prospectively enrolled in this clinical study. The Ocular Surface Disease Index (OSDI) questionnaire, Schirmer Ⅰ test (SⅠT), tear breakup time (BUT), and corneal fluorescein staining were evaluated preoperatively and 3, 6, and 12 months postoperatively. Data from the two groups were analyzed with a two-way repeated measures ANOVA. Results: There were no statistically significant differences between the two groups for the OSDI questionnaire score, SⅠT, and corneal fluorescein staining at all time-points and for the preoperative and 3 and 6 months postoperative BUT (P>0.05). The BUT of the FS-LASIK group was higher than that for the LASEK group after 12 months (t=2.81, P=0.01). Compared with the preoperative evaluation, corneal staining increased in the FS-LASIK group after 3 months (t=3.48, P=0.008), but there were no statistically significant differences between 6 and 12 months postoperative and the preoperative. There were no statistically significant differences between postoperative and preoperative for the corneal fluorescein staining in the LASEK group (P>0.05). There were no statistically significant differences between postoperative and preoperative for the OSDI questionnaire score and Schirmer Ⅰ in both groups (P>0.05), and there were no statistically significant differences between 3 and 6 months postoperative and the preoperative for the BUT in both groups (P>0.05). Compared with the preoperative evaluation, the BUT increased in the FS-LASIK and LASEK groups after 12 months (t=3.14, P=0.01; t=2.43, P=0.04). Conclusions: Dry eye is slight after FS-LASIK and off-flap LASEK surgeries, and both techniques have a similar effect on dry eye. Key words: femtosecond laser; laser in situ keratomileusis; laser epithelial keratomileusis; dry eye
{"title":"Comparative Study of Dry Eye after FS-LASIK and Off-Flap LASEK","authors":"Q. Hu, Lingli Xu, Rong Ma, Zhe Zhang, Wei Mao, Yusheng Zhou","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.06.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.06.002","url":null,"abstract":"Objective: \u0000To compare dry eye characteristics in eyes after femtosecond laser-assisted in situ keratomileusis (FS-LASIK) or off-flap laser epithelial keratomileusis (LASEK). \u0000 \u0000 \u0000Methods: \u0000Thirty eyes of 30 patients with myopia who had FS-LASIK (FS-LASIK group) and 30 eyes of 30 patients with myopia who had off-flap LASEK (LASEK group) at the Refractive Surgery Center of the Ningbo Eye Hospital from August 2016 to February 2017 were prospectively enrolled in this clinical study. The Ocular Surface Disease Index (OSDI) questionnaire, Schirmer Ⅰ test (SⅠT), tear breakup time (BUT), and corneal fluorescein staining were evaluated preoperatively and 3, 6, and 12 months postoperatively. Data from the two groups were analyzed with a two-way repeated measures ANOVA. \u0000 \u0000 \u0000Results: \u0000There were no statistically significant differences between the two groups for the OSDI questionnaire score, SⅠT, and corneal fluorescein staining at all time-points and for the preoperative and 3 and 6 months postoperative BUT (P>0.05). The BUT of the FS-LASIK group was higher than that for the LASEK group after 12 months (t=2.81, P=0.01). Compared with the preoperative evaluation, corneal staining increased in the FS-LASIK group after 3 months (t=3.48, P=0.008), but there were no statistically significant differences between 6 and 12 months postoperative and the preoperative. There were no statistically significant differences between postoperative and preoperative for the corneal fluorescein staining in the LASEK group (P>0.05). There were no statistically significant differences between postoperative and preoperative for the OSDI questionnaire score and Schirmer Ⅰ in both groups (P>0.05), and there were no statistically significant differences between 3 and 6 months postoperative and the preoperative for the BUT in both groups (P>0.05). Compared with the preoperative evaluation, the BUT increased in the FS-LASIK and LASEK groups after 12 months (t=3.14, P=0.01; t=2.43, P=0.04). \u0000 \u0000 \u0000Conclusions: \u0000Dry eye is slight after FS-LASIK and off-flap LASEK surgeries, and both techniques have a similar effect on dry eye. \u0000 \u0000 \u0000Key words: \u0000femtosecond laser; laser in situ keratomileusis; laser epithelial keratomileusis; dry eye","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"11 1","pages":"408-413"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75257494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2019.06.011
Yang Liu, Lin-nong Wang, An-Quan Xue, Guiyang Zhao
Objective: To investigate the therapeutic effect of posterior scleral contraction on macular splitting in pathologic myopia. Methods: This was a retrospective study. Posterior scleral contraction was performed on 45 eyes (24 cases) with macular cleft palate from December 2014 to April 2017 from Nanjing First Hospital. Outcomes, including BCVA, ocular axial length, refractive error, central foveal thickness and surgical complications, were observed at the preoperative baseline and postoperatively 1, 3, 6 and 12 months. Data were performed by repeated measures analysis of variance. Results: Central foveal thickness preoperatively and postoperatively at 1, 3, 6 and 12 months was 494±31, 299±24, 256±24, 200±22, 168±25 μm, respectively. Both decreased significantly compared with preoperative measurements (P 0.05). Refractive errors at 1 and 3 months were -15.14±5.16 D and -15.64±5.05 D, which was a statistically significant diminishment compared to the baseline (-17.33±7.43 D)(P 0.05). There was no statistically significant difference of BCVA between the preoperative and the postoperative (P>0.05). Conclusions: Posterior scleral contraction might become a safe and effective way to treat macular cleavage in high myopia with or without retinal detachment. Key words: myopia; macular cleft; posterior scleral contraction
{"title":"Clinical Observation of Posterior Scleral Buckling in the Treatment of Pathological Myopia with Macular Splitting","authors":"Yang Liu, Lin-nong Wang, An-Quan Xue, Guiyang Zhao","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.06.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.06.011","url":null,"abstract":"Objective: \u0000To investigate the therapeutic effect of posterior scleral contraction on macular splitting in pathologic myopia. \u0000 \u0000 \u0000Methods: \u0000This was a retrospective study. Posterior scleral contraction was performed on 45 eyes (24 cases) with macular cleft palate from December 2014 to April 2017 from Nanjing First Hospital. Outcomes, including BCVA, ocular axial length, refractive error, central foveal thickness and surgical complications, were observed at the preoperative baseline and postoperatively 1, 3, 6 and 12 months. Data were performed by repeated measures analysis of variance. \u0000 \u0000 \u0000Results: \u0000Central foveal thickness preoperatively and postoperatively at 1, 3, 6 and 12 months was 494±31, 299±24, 256±24, 200±22, 168±25 μm, respectively. Both decreased significantly compared with preoperative measurements (P 0.05). Refractive errors at 1 and 3 months were -15.14±5.16 D and -15.64±5.05 D, which was a statistically significant diminishment compared to the baseline (-17.33±7.43 D)(P 0.05). There was no statistically significant difference of BCVA between the preoperative and the postoperative (P>0.05). \u0000 \u0000 \u0000Conclusions: \u0000Posterior scleral contraction might become a safe and effective way to treat macular cleavage in high myopia with or without retinal detachment. \u0000 \u0000 \u0000Key words: \u0000myopia; macular cleft; posterior scleral contraction","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"28 1","pages":"464-469"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77961559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-25DOI: 10.3760/CMA.J.ISSN.1674-845X.2019.06.003
Ying Kang, Hua Wang
Objective: To observe and evaluate the changes in visual quality after corneal topography-guided FS-LASIK for myopia and astigmatism. Methods: This was a prospective study. Forty patients (68 eyes) with myopia or myopic astigmatism were selected from June to October 2017 in the Optometry Center, Hunan People's Hospital and divided into a middle-high astigmatism group (32 eyes, astigmatism >1.0 D) and a low astigmatism group (36 eyes, astigmatism ≤1.0 D). The corneal topography-guided FS-LASIK was used. The preoperative and postoperative 3-month visual acuity (UCVA), best corrected visual acuity (BCVA), refractive error, corneal total higher-order aberrations, corneal spherical aberration, corneal coma, MTF cutoff and objective scattering index (OSI) were recorded. Data were analyzed using t test. Results: The UCVA of 100% of the eyes reached preoperative BCVA at 3 months after surgery. The UCVA (LogMAR) of the patients at 3 months after operation was -0.10±0.07, which was significantly higher than that of preoperative BCVA (LogMAR) -0.02±0.07 (t=8.714, P<0.001). The prevalence of spherical equivalent (SE) within ±0.50 was 94%; the residual astigmatism was 0.40±0.17 D. At 3 months, postoperative coma and OSI decreased compared with preoperative levels, and the MTF cutoff increased compared with preoperative levels. The difference was statistically significant (t=1.757, -2.935, 4.243, P<0.05). The UCVA, coma and MTF of the moderate and high astigmatism group and the low astigmatism group had improved at 3 months after surgery, and there was no significant difference between the two groups. Conclusions: FS-LASIK guided by corneal topography can effectively improve the visual quality of myopic astigmatism patients. Key words: corneal topography guide; femtosecond laser; laser in situ keratomileusis; myopia; astigmatism; visual quality
{"title":"Evaluation of the Visual Quality in Myopic and Astigmatic Patients Treated with Corneal Topography-Guided FS-LASIK","authors":"Ying Kang, Hua Wang","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.06.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.06.003","url":null,"abstract":"Objective: \u0000To observe and evaluate the changes in visual quality after corneal topography-guided FS-LASIK for myopia and astigmatism. \u0000 \u0000 \u0000Methods: \u0000This was a prospective study. Forty patients (68 eyes) with myopia or myopic astigmatism were selected from June to October 2017 in the Optometry Center, Hunan People's Hospital and divided into a middle-high astigmatism group (32 eyes, astigmatism >1.0 D) and a low astigmatism group (36 eyes, astigmatism ≤1.0 D). The corneal topography-guided FS-LASIK was used. The preoperative and postoperative 3-month visual acuity (UCVA), best corrected visual acuity (BCVA), refractive error, corneal total higher-order aberrations, corneal spherical aberration, corneal coma, MTF cutoff and objective scattering index (OSI) were recorded. Data were analyzed using t test. \u0000 \u0000 \u0000Results: \u0000The UCVA of 100% of the eyes reached preoperative BCVA at 3 months after surgery. The UCVA (LogMAR) of the patients at 3 months after operation was -0.10±0.07, which was significantly higher than that of preoperative BCVA (LogMAR) -0.02±0.07 (t=8.714, P<0.001). The prevalence of spherical equivalent (SE) within ±0.50 was 94%; the residual astigmatism was 0.40±0.17 D. At 3 months, postoperative coma and OSI decreased compared with preoperative levels, and the MTF cutoff increased compared with preoperative levels. The difference was statistically significant (t=1.757, -2.935, 4.243, P<0.05). The UCVA, coma and MTF of the moderate and high astigmatism group and the low astigmatism group had improved at 3 months after surgery, and there was no significant difference between the two groups. \u0000 \u0000 \u0000Conclusions: \u0000FS-LASIK guided by corneal topography can effectively improve the visual quality of myopic astigmatism patients. \u0000 \u0000 \u0000Key words: \u0000corneal topography guide; femtosecond laser; laser in situ keratomileusis; myopia; astigmatism; visual quality","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"27 1","pages":"414-419"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78158373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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