Chinese Journal of Optometry & Ophthalmology最新文献

{"title":"Comparison of the Clinical Effects of Bromfenac Sodium and Fluorometholone after LASEK Surgery","authors":"Kun-Ju Yang","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.07.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.07.005","url":null,"abstract":"Objective: \u0000To compare the effectiveness of bromfenac sodium and fluorometholone eye drops on relieving corneal irritation and its safety in clinical applications after laser epithelial keratomileusis (LASEK) surgery. \u0000 \u0000 \u0000Methods: \u0000This was a prospective randomized, controlled study. A total of 60 patients (120 eyes) who underwent LASEK surgery from April 2017 to February 2018 in Tianjin Eye Hosptial were divided randomly into a bromfenac sodium group and a fluorometholone group according to the random number table, 30 patients (60 eyes) were included in each group. In the first week after the surgery, the bromfenac sodium group was given 0.1% bromfenac sodium eye drops twice a day, and then from the second week, this eye drops changed to 4 times per day for 1 month and 2 times per day in the following month. While the fluorometholone group was given 0.3% sodium hyaluronate eye drops twice a day in the first week after the surgery, then the eye drops changed to 0.1% fluorometholone by giving 4 times per day, which was gradually tapered in every month to the end. Corneal irritation and epithelial healing were evaluated at 1 d, 2 d, 3 d and 5 d after surgery. Examinations of uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), refraction, slit lamp, Schirmer Ⅰ test (SⅠT), tear film break-up time (BUT) and corneal epithelium integrity evaluation were performed 1 week, 1 month and 3 months after surgery. An intraocular pressure (IOP) examination was performed 1 week, 2 weeks, 1 month, 3 months and 4 months. The data were analyzed by repeated measures ANOVA, independent sample t-test and Mann-Whitney U test. \u0000 \u0000 \u0000Results: \u0000The scores for corneal irritation in the bromfenac sodium group were significantly lower than those in the fluorometholone group after surgery (Fgroups=7.8, P=0.018; Ftimes=121.7, P<0.001; Finteraction=273.4, P<0.001). At 1 month after surgery, the mean visual acuity of both groups recovered to 1.0 or better. There were no statistically significant differences in UCVA, BCVA or refraction between the two groups. At 1 month after surgery, there were 6 cases (10%) of corneal haze in the bromfenac sodium group while there were 2 cases (3%) in the fluorometholone group. The correction of IOP in the bromfenac sodium group after surgery were all below 21 mmHg, while there were 5 cases (9%) of high IOP at 2 weeks and 3 cases (5%) at 1 month in the fluorometholone group. After 3 months, both SⅠT and BUT in the two groups returned to normal levels, and the difference was not statistically significant. After 3 months, the corneal epithelium had totally recovered in most of the patients in the two groups. There was no statistically significant difference between the two groups. \u0000 \u0000 \u0000Conclusions: \u0000Bromfenac sodium eye drops can effectively alleviate corneal irritation after LASEK surgery. It is safe and effective for the recovery of vision and anti-inflammatory effects. Furthermore, bromfenac sodium can reduce the risk of post","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"48 1","pages":"507-513"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79935176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Application of Optical Coherence Tomography Angiography in Glaucoma","authors":"Linhong Ye, Qinghui Yuan","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.07.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.07.013","url":null,"abstract":"Optical coherence tomography angiography (OCTA) is a new, non-invasive imaging system, can produce the structure data of retina and choroid, shows the structure and blood flow information. Split-spectrum amplitude-decorrelation angiography (SSADA) algorithman (an important part of OCTA) can help reduce the signal-to-noise ratio, enhancing visualization of retinal vasculature using motion contrast. OCTA can provide more meaningful image data for the treatment which is a major breakthrough in the eye detection method. Currently there is lack of effective early diagnosis methods for glaucoma. OCTA as a parameter, can evaluate the structural parameters of glaucoma. This article will review the application of this new non-invasive method in the clinical application of three types of glaucoma: Angle-closure glaucoma, open angle glaucoma and normal tension glaucoma. \u0000 \u0000 \u0000Key words: \u0000optical coherence tomography angiography; glaucoma; application","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"29 1","pages":"557-560"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81070965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Binocular Visual Function after SMILE","authors":"K. Du, Xiaoying Wu, D. Wen, B. Xiao, Shuang-zhen Liu, Yewei Yin, Chenling Li, Shengfa Hu","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.07.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.07.007","url":null,"abstract":"Objective: \u0000To investigate the effect of small incision lenticule extraction (SMILE) on binocular visual function and its clinical significance. \u0000 \u0000 \u0000Methods: \u0000In this prospective clinical study, 58 myopia patients (116 eyes) who completed the SMILE surgery at the Xiangya Hospital of Central South University from March 2016 to October 2017 were selected. According to the degree of spherical equivalent (SE), patients were divided into a high myopia group (<-6.00 D) (40 eyes) and a mild-moderate myopia group (≥-6.00 D) (76 eyes). Based on the dominant eye, participants were divided into a dominant eye group (58 eyes) and a nondominant eye group (58 eyes). For all patients, accommodative and convergence function were measured before surgery and 1 week and 1 and 3 months after surgery. Repeated measures analysis of variance and independent t-tests were used to analyze and compare the data from the two groups. \u0000 \u0000 \u0000Results: \u0000①The SEs of the two groups after 1 week, 1 month, and 3 months were lower than those before surgery (P<0.05). In the mild-moderate myopia group, the dominant eye amplitude of the postoperative accommodation and the positive relative accommodation were both larger than those before surgery (P<0.05). Binocular accommodative facility increased 1 month and 3 months after surgery (P<0.05). There were no statistically significant differences in similar indicators between the high myopia group at each time point before or after surgery. There was no significant difference between the mild-moderate myopia group and the high myopia group in the amplitude of accommodation of the dominant and non-dominant eyes at each time point before and after surgery. ②There was no statistically significant difference between the preoperative mild-moderate myopia group and the high myopia group in near and distance phoria, NRV/PRV, and AC/A. The postoperative near-points in the low-moderate myopia group and the high myopia group increased compared with preoperative measurements (P<0.05). \u0000 \u0000 \u0000Conclusions: \u0000SMILE surgery has a positive effect on accommodative and convergence function in patients with mild-moderate myopia. For patients with high myopia, changes in postoperative binocular visual function are not obvious. \u0000 \u0000 \u0000Key words: \u0000small incision lenticule extraction; myopia; accommodation; vergence; binocular visual function symptom","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"2 1","pages":"521-526"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75690006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Monocular Vision Decline on Binocular Contrast Sensitivity","authors":"S. Tan, Jie-Min Chen, Meng Wang, Xiao-ying Yu, Yiyang Lei, Wei Tang, W. Xia","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.07.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.07.008","url":null,"abstract":"Objective: \u0000To study the changes in binocular contrast sensitivity (CS) when monocular vision declines, and to explore the effects of monocular vision decline on binocular function and interaction, and to explore the value of judicial appraisal. \u0000 \u0000 \u0000Methods: \u0000In this experimental study, 46 normal subjects (24 males and 22 females) were enrolled in Academy of Forensic Science from March 2016 to August 2017. Monocular visual acuity of them could be corrected to more than 4.9. Experimental lenses were placed in front of the dominant eyes to induce experimental monocular visual impairment in varying degrees. Visual acuity and CS for monocular and binocular function were measured. Binocular summation ratios (BSR) were calculated, further spherical tests, analysis of variance and the Kruskal-Wallis test. \u0000 \u0000 \u0000Results: \u0000Decreased monocular vision can cause a certain decrease in binocular vision, but binocular vision is still better than monocular vision. When visual acuity declined to the level of mild damage, the normal inverted U-shaped curve of the whole frequency band was destroyed, and visual acuity had a more obvious decline at medium and high spatial frequencies than at low spatial frequencies. At high frequencies and normal visual acuity in both eyes, the maximum sum of both eyes appeared (BSR=1.48). When monocular visual acuity gradually declined, the binocular average and inhibition appeared (BSR<1). There was a certain degree of tolerance and spatial dependence with binocular interaction. \u0000 \u0000 \u0000Conclusions: \u0000Decreased monocular vision has a certain influence on binocular CS and the form and degree of binocular interaction. A binocular CS test can reflect the degree of monocular vision loss. It has practical value and is worthy of clinical application and judicial expertise. \u0000 \u0000 \u0000Key words: \u0000monocular visual acuity; binocular contrast sensitivity; binocular interaction","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"2 1","pages":"527-533"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74608548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of Angle Kappa in Cataract Patients and Changes under Photopic and Mesopic Conditions","authors":"Mengqiong Li, Z. Mao","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.07.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.07.004","url":null,"abstract":"Objective: \u0000To observe the characteristics and rule of change of the angle Kappa in cataract patients under photopic and mesopic conditions. \u0000 \u0000 \u0000Methods: \u0000In this case series study, a total of 788 eyes in 394 cataract patients receiving cataract surgery in the Affiliated Eye Center of Xiamen University were selected from May 2016 to October 2017. All patients were examined by OPD-Scan Ⅲ. The collected data included the clinical data of patients (such as age, gender, ocular history and surgical history), as well as preoperative biometric data, including mean corneal keratometry (mean K), and corneal spherical aberration (CSA), white-to-white distance (WTW), photopic pupil diameter (Photopic), mesopic pupil diameter (Mesopic), distance and angle of photopic angle Kappa (PDist@Angle), distance and angle of mesopic angle Kappa (MDist@Angle), and distance and angle from the mesopic pupil center to the photopic pupil center (MPDist@Angle) and so on. Specific tests included Rank sum test, Chi-square test, and multiple regression statistical analysis. \u0000 \u0000 \u0000Results: \u0000There were no significant differences in the biometric data, such as mean K, MPDist, PDist, WTW, and CSA between the two eyes (P>0.05), but the differences in photopic pupil diameter, mesopic pupil diameter, and MDist between the two eyes were statistically significant (Z=2.276, 3.284, 2.388, all P<0.05). The angle Kappa for most patients in the two eyes under photopic or mesopic conditions was positive, and the pupil center usually shifted inferotemporally when the illumination was changed from photopic to mesopic. The clinical and biometric data for both eyes were analyzed by multiple regression analysis with MPDist. The regression equation of the right eye was MPDist=0.033+0.505×MDist+0.041×CSA-0.319×PDist (F=45.0, P<0.001), while that of the left eye was MPDist=-0.002+0.547×MDist+0.013×Mesopic-0.350×PDist (F=61.6, P<0.001). \u0000 \u0000 \u0000Conclusions: \u0000In cataract patients, most eyes have a positive angle Kappa, and the variation in pupil size under different illuminations affect the size of the angle Kappa. Large differences can be detected in photopic pupil size, mesopic pupil size and the direction and shift of the pupil center during photopic and mesopic alternation. There was a linear regression relationship between MPDist changes and PDist, MDist, Mesopic, CSA. Among them, MPDist of both eyes were negatively correlated with PDist, and MDist of both eyes had relatively larger influence on MPDist changes. \u0000 \u0000 \u0000Key words: \u0000angle Kappa; cataract; photopic and mesopic pupil","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"27 1","pages":"499-506"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86126457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Changes in Astigmatism after Correction of Senile Upper Eyelid Skin Laxity","authors":"Renhui Dou, S. Wen, Xiaoyu Yu, H. Guo","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.07.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.07.011","url":null,"abstract":"Objective: \u0000To investigate the early changes in ocular refraction after correction of upper eyelid skin laxity. \u0000 \u0000 \u0000Methods: \u0000This was a prospective case-control study. Patients with senile upper eyelid skin laxity were recruited from the Eye Hospital of Wenzhou Medical University at Hangzhou from July 2016 to December 2017. Sixty-two patients were divided into two groups: 40 patients (80 eyes) who underwent surgery were included in the treatment group, 22 patients (44 eyes) who declined surgery were included in the control group. The treatment group was examined preoperatively and 3 months postoperatively. The control group was initially examined and then re-examined 3 months later. The best corrected visual acuity, refractive errors, corneal curvature and central corneal thickness were analyzed. Paired t tests or rank sum tests were used to compare the differences within a groups, covariance analysis was used to compare the differences between the groups. \u0000 \u0000 \u0000Results: \u0000In the treatment group, astigmatism decreased after surgery; the mean change was 0.17 D (t=-3.31, P<0.001). There were no significant differences in corrected visual acuity, spherical equivalent diopter, corneal curvature or corneal thickness before and after surgery. There were no statistical differences in the control group when testing results were compared. There was a significant difference in astigmatism between the two groups (F=13.672, P<0.001), but no statistical differences in corrected visual acuity, spherical equivalent diopter, corneal curvature or corneal thickness. \u0000 \u0000 \u0000Conclusions: \u0000Astigmatism decreased early after surgical correction, but the astigmatic axis had no significant change. \u0000 \u0000 \u0000Key words: \u0000upper eyelid skin laxity; refraction; surgery","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"57 1","pages":"549-552"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89859871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Olfactory Neuroblastoma First Diagnosed as an Orbital Mass after Trauma: A Case Report","authors":"Qiqi Xing, C. Ding, Dongdong Liu","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.07.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.07.012","url":null,"abstract":"","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"3 1","pages":"553-556"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74336632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consistency of Corneal Thickness and Anterior Chamber Depth Measured by Pentacam and VX120","authors":"Qing-wei Zhang, C. Zhai, Dong-li Ma, Jing Zhang","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.07.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.07.002","url":null,"abstract":"Objective: \u0000To compare the consistency of central corneal thickness (CCT), minimum corneal thickness (MinCT) and anterior chamber depth (ACD) measured by Pentacam and VX120. \u0000 \u0000 \u0000Methods: \u0000In this case series study, 71 myopia patients with (142 eyes) who planned to receive refractive surgery were enrolled from the March 2018 to April 2018, in Beijing Tongren Hospital. All subjects were under CCT, MinCT, ACD measurement by Pentacam and VX120. Due to that data of both eyes were used, thus a Rosner-Glynn-Lee method was used to make correction. The clustered rank sign test was used to compare the measurements of different equipment. The intra-class correlation coefficient (ICC) and Bland-Altman 95% limits of agreement were used to measure the consistency of measurement of different equipment. \u0000 \u0000 \u0000Results: \u0000CCT, ACD measured by the VX120 was lower than Pentacam (Z=3.524, 7.446, all P<0.001). There was no statistical difference in the measurement of MinCT between VX120 and Pentacam (Z=0.679, P=0.497). The ICC of MinCT measured by VX120 and Pentacam was 0.9 and the Bland-Altman plot showed that 93.7% of the data were distributed within the confidence interval. The 95% limits of agreement of MinCT were -27.81 to 29.26 μm for these two devices. \u0000 \u0000 \u0000Conclusions: \u0000VX120 has a high consistency with Pentacam on the measurement of MinCT. However, the measurements acquired by VX120 should not be directly interchangeable with Pentacam measurements in clinical practice. \u0000 \u0000 \u0000Key words: \u0000VX120; Pentacam; consistency; corneal thickness; minimum corneal thickness; anterior chamber depth","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"148 1","pages":"488-492"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77830174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community Survey of Low Vision in Two Communities of Beijing in China","authors":"Yan-hong Zou, Qian Li, S. Cui, Wei Jia, Xi-pu Liu","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.07.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.07.003","url":null,"abstract":"Objective: \u0000To investigate the visual function, major causes of visual impairment, vision-related quality of life and rehabilitation needs of low vision patients in two communities of Beijing. \u0000 \u0000 \u0000Methods: \u0000Visually disabled people registered in the Desheng community, Xicheng district and the Jiuxianqiao community, Chaoyang district in Beijing were included in this cross sectional epidemiological study from September 2013 to April 2015. Interviews, visual acuity tests, slit lamp examination, and funduscopy were performed. Vision-related quality of life, a questionnaire about living conditions and rehabilitation needs were recorded during home visits. Data were analyzed with a χ2 test, t test or rank-sum test. Logistic regression were used to identify the factors relevant to vision-related quality of life. \u0000 \u0000 \u0000Results: \u0000There were 388 visually disabled people registered in these two communities. One hundred fifty-one patients (39.0%) were visited and evaluated at home. Of the 151 participants, 110(74.3%) were identified as low vision according to the Bangkok-Madrid standard. Among them, 66 patients (60.0%) had a best corrected visual acuity for either eye that was lower than 0.05 or the residual visual field radius was less than 10°. The main causes for visual impairment were retinal or uveal diseases 55(50.0%), glaucoma 15(13.6%), or congenital or inherited diseases 15(13.6%). Their main rehabilitation needs were going outside by themselves and reading, which amounted to 81.8%. The average score for quality of life was 47.3±26.7 with a personal interview using the low vision quality-of-life questionnaire (LVQOL). No significant relationship was found between score and sex, age, or vision function among low vision patients. But for all participants, age and residual visual field were the main factors related to quality of life (P<0.001). \u0000 \u0000 \u0000Conclusions: \u0000Low vision people accounted for the major portion of visually disabled people in two Beijing communities. Their visual function is poor, and quality of life drops dramatically. The main causes of their visual impairments are irreversible eye diseases. They need the most help are going outside and reading. \u0000 \u0000 \u0000Key words: \u0000low vision; vision related quality of life; visual rehabilitation; community; Beijing","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"90 1","pages":"493-498"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72828374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Treatment of Vitrectomy Combined with Internal Limiting Membrane Peeling in Diabetic Macular Edema","authors":"Shixin Zhao, Hanfei Wu, Lijun Shen, J. Mao, Yiqi Chen","doi":"10.3760/CMA.J.ISSN.1674-845X.2019.06.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-845X.2019.06.006","url":null,"abstract":"Objective: \u0000To investigate the effects of vitrectomy combined with internal limiting membrane (ILM) peeling indiabetic macular edema (DME). \u0000 \u0000 \u0000Methods: \u0000In this retrospective clinical study, 33 eyes of 31 patients with DME confirmed preoperatively or intraoperatively by optical coherence tomography (OCT) were included. All patients underwent vitrectomy for dense vitreous hemorrhages due to diabetic retinopathy or proliferative diabetic retinopathy between June 2014 and January 2017 at the Eye Hospital, Wenzhou Medical University. A total of 16 patients (18 eyes) with vitrectomy and ILM peeling were in the ILM-removed group, 15 eyes of 15 patients with vitrectomy only were in the control group. All the surgeries were performed by the same surgeon. All subjects underwent OCT examination at 1 month and 3 months postoperatively. The central macular thickness (CMT) and visual outcomes between the two groups were analyzed relative to each other. The data were analyzed by repeated measures analysis and t-tests. \u0000 \u0000 \u0000Results: \u0000Before the therapy, and at one and three months after therapy, the total difference of best corrected visual acuity (BCVA) between the two groups was statistically significant (F=15.93, P<0.001). The BCVA in the ILM-removed group was higher than the control group at one month after therapy (t=2.55, P=0.02). However, there was no significant difference between the two groups in terms of BCVA at three months after therapy (t=0.82, P=0.42). Before the therapy, and at one and three months after therapy, the total difference of CMT between the two groups was not statistically significant (F=2.85, P=0.065). At both one month and three months after therapy, the CMT in the ILM-removed group was lower than the control group (t=2.24, P=0.03; t=3.79, P=0.001). At 1 month postoperatively, the subjects of effectiveness (a decrease in CMT by at least 20%), ineffectiveness (a change in CMT by <20%) and deterioration (an increase in CMT by more than 20%) were 8, 6 and 4 respectively, while the subjects were 11, 5 and 2 respectively at 3 months after therapy. There was no significant difference from the control group (Z=-1.687, P=0.092) at one month after therapy, but there was a significant difference at three months after therapy (Z=-2.177, P=0.029). \u0000 \u0000 \u0000Conclusions: \u0000The removal of ILM contributes to the resolution of nontractional DME at an early stage after therapy. \u0000 \u0000 \u0000Key words: \u0000diabetic macular edema; vitrectomy; internal limiting membrane","PeriodicalId":10142,"journal":{"name":"Chinese Journal of Optometry & Ophthalmology","volume":"61 1","pages":"433-438"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85721418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}