Objective: The effects of prenatal coronavirus 2019 disease (COVID-19) exposure on the infantile neurological development are unknown. It has been considered that the inflammatory, thrombotic, and vascular changes occurred in the placentas taken from pregnant women diagnosed with COVID-19 and the inflammatory nature of COVID-19 infection may lead to negative obstetric and neurological events. We aimed to assess the potential neurological effects of prenatal COVID-19 exposure on the infant. Methods: The present study included 2–12-month-old infants born to women with positive real-time reverse transcription polymerase chain reaction test results for COVID-19 from the population of pregnant patients under routine follow-up. The neurological examinations and the Denver II Developmental Screening Test (DDST II) were performed for 41 infants aged 2–12 months to assess the neurological effects of prenatal COVID-19 exposure. Results: The average gestational age of the infants was 38.7 ± 1.9 weeks, and the average birth weight was 3198 ± 543 g. Eight of the infants had a history of hospitalization in the neonatal intensive care unit. The neurological examination and the neuromotor development of 40 (96%) infants were normal for their age group. Only one infant had abnormal neurological examination and DDST II result. Conclusion: The findings of the study suggest that prenatal COVID-19 exposure has no negative neurological impact on infants. Long-term prospective studies with larger sample sizes are needed for more comprehensive assessment of the neurological effects of prenatal COVID-19 exposure on the infants.
{"title":"The Assessment of Neurological Development of the Infants with Prenatal COVID-19 Exposure","authors":"Senem Ayça, Semra Yüksel, Hatice Yaşat Nacar, Pınar Arıcan","doi":"10.33808/clinexphealthsci.1102756","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1102756","url":null,"abstract":"Objective: The effects of prenatal coronavirus 2019 disease (COVID-19) exposure on the infantile neurological development are unknown. It has been considered that the inflammatory, thrombotic, and vascular changes occurred in the placentas taken from pregnant women diagnosed with COVID-19 and the inflammatory nature of COVID-19 infection may lead to negative obstetric and neurological events. We aimed to assess the potential neurological effects of prenatal COVID-19 exposure on the infant. \u0000Methods: The present study included 2–12-month-old infants born to women with positive real-time reverse transcription polymerase chain reaction test results for COVID-19 from the population of pregnant patients under routine follow-up. The neurological examinations and the Denver II Developmental Screening Test (DDST II) were performed for 41 infants aged 2–12 months to assess the neurological effects of prenatal COVID-19 exposure. \u0000Results: The average gestational age of the infants was 38.7 ± 1.9 weeks, and the average birth weight was 3198 ± 543 g. Eight of the infants had a history of hospitalization in the neonatal intensive care unit. The neurological examination and the neuromotor development of 40 (96%) infants were normal for their age group. Only one infant had abnormal neurological examination and DDST II result. \u0000Conclusion: The findings of the study suggest that prenatal COVID-19 exposure has no negative neurological impact on infants. Long-term prospective studies with larger sample sizes are needed for more comprehensive assessment of the neurological effects of prenatal COVID-19 exposure on the infants.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48485727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.33808/clinexphealthsci.951967
Münevver Sönmez, Öznur Gürlek Kısacık
Objective: This study aimed to determine how Turkish nursing students’ perceived nursing diagnosis. Methods: This descriptive and cross-sectional study was carried out with 655 nursing students in the Departments of Nursing in the Health Sciences Faculties of two universities, in the Aegean and western Black Sea Region, between 15 February and 5 April 2020. The Students Information Form and Perceptions of Nursing Diagnosis Scale were used for data collection. The independent samples t-test, one-way ANOVA test, and the Mann-Whitney U-test with Bonferroni-correction were used to determine the differences between the groups. Pearson correlation analysis was used to determine the effects of independent variables Results: The mean age of the nursing students was 21.12±1.39; 76.6% of them were female and 36.8% were in the second-year. 53.7% of the nursing students reported that they had difficulty in making nursing diagnoses. The overall Perceptions of Nursing Diagnosis Survey score of the nursing students was found to be 2.46±051. Statistically significant difference was found between Perceptions of Nursing Diagnosis Survey scores in terms of gender (p=0.012), the necessity of nursing diagnosis (p<0.001), and having sufficient knowledge about nursing diagnosis (p=0.019). Conclusions: The findings of this study have revealed that Turkish nursing students’ perceptions of nursing diagnoses are positive. It is important that use effective teaching methods in teaching nursing diagnoses in fundamental nursing education, to give more importance to nursing diagnoses. It is recommended to plan qualitative studies to in-depth examine students’ perceptions with randomized controlled studies involving innovative educational interventions in the future
{"title":"Perceptions of Turkish Nursing Students on Nursing Diagnose","authors":"Münevver Sönmez, Öznur Gürlek Kısacık","doi":"10.33808/clinexphealthsci.951967","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.951967","url":null,"abstract":"Objective: This study aimed to determine how Turkish nursing students’ perceived nursing diagnosis.\u0000Methods: This descriptive and cross-sectional study was carried out with 655 nursing students in the Departments of Nursing in the Health Sciences Faculties of two universities, in the Aegean and western Black Sea Region, between 15 February and 5 April 2020. The Students Information Form and Perceptions of Nursing Diagnosis Scale were used for data collection. The independent samples t-test, one-way ANOVA test, and the Mann-Whitney U-test with Bonferroni-correction were used to determine the differences between the groups. Pearson correlation analysis was used to determine the effects of independent variables\u0000Results: The mean age of the nursing students was 21.12±1.39; 76.6% of them were female and 36.8% were in the second-year. 53.7% of the nursing students reported that they had difficulty in making nursing diagnoses. The overall Perceptions of Nursing Diagnosis Survey score of the nursing students was found to be 2.46±051. Statistically significant difference was found between Perceptions of Nursing Diagnosis Survey scores in terms of gender (p=0.012), the necessity of nursing diagnosis (p<0.001), and having sufficient knowledge about nursing diagnosis (p=0.019).\u0000Conclusions: The findings of this study have revealed that Turkish nursing students’ perceptions of nursing diagnoses are positive. It is important that use effective teaching methods in teaching nursing diagnoses in fundamental nursing education, to give more importance to nursing diagnoses. It is recommended to plan qualitative studies to in-depth examine students’ perceptions with randomized controlled studies involving innovative educational interventions in the future","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43168039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.33808/clinexphealthsci.891578
Seda Karaçay Yıkar, Ebru Gözüyeşil, E. Nazik, Ebru Var
Objective: Evaluation of the care given in the postpartum period is vital in terms of the quality of care. The aim of this study was to evaluate nursing care in the early postpartum period. Methods: This descriptive and cross-sectional study was conducted in a postpartum clinic between December 2016 and January 2017 with 130 mothers in postpartum period, and 18 nurses and midwives working in the same postpartum clinic. Data were collected using a personal information form, and the Postpartum Nursing Care Evaluation Tool (PPNCET). The data analysis was conducted using percentages, arithmetic mean, independent samples t-test, Mann-Whitney U test, and Kruskal-Wallis test. Results: The mean age of the mothers was 26.80 ± 4.90, and of the nurses and midwives was 35.83 ± 12.14. The mean PPNCET score of the mothers was 141.58 ± 32.03. The mean care subscale score of the mothers was 69.88 ± 12.06 and of the education subscale was 71.70 ± 19.97. The mean PPNCET score of the nurses and midwives was 153.50 ± 23.18. The mean care subscale score of the nurses and midwives was 73.38 ± 8.84, and the mean education subscale score was 80.11 ± 14.33. Conclusions: The mean PPNCET score of mothers and nurses and midwives were higher than the average. Higher PPNCET scores of the nurses and midwives compared to the mothers suggests that either the postpartum care given was not perceived as adequate by the mothers, or the care was not served in adequate quality. To increase postpartum care satisfaction of the mothers, involving nurses and midwives in the care process more is suggested. In line with these results, planning in-service training programs to develop the knowledge and skills of the nurses and midwives would be beneficial in increasing the quality of service
{"title":"Evaluation of Nursing Care in the Early Postpartum Period","authors":"Seda Karaçay Yıkar, Ebru Gözüyeşil, E. Nazik, Ebru Var","doi":"10.33808/clinexphealthsci.891578","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.891578","url":null,"abstract":"Objective: Evaluation of the care given in the postpartum period is vital in terms of the quality of care. The aim of this study was to evaluate nursing care in the early postpartum period. \u0000Methods: This descriptive and cross-sectional study was conducted in a postpartum clinic between December 2016 and January 2017 with 130 mothers in postpartum period, and 18 nurses and midwives working in the same postpartum clinic. Data were collected using a personal information form, and the Postpartum Nursing Care Evaluation Tool (PPNCET). The data analysis was conducted using percentages, arithmetic mean, independent samples t-test, Mann-Whitney U test, and Kruskal-Wallis test. \u0000Results: The mean age of the mothers was 26.80 ± 4.90, and of the nurses and midwives was 35.83 ± 12.14. The mean PPNCET score of the mothers was 141.58 ± 32.03. The mean care subscale score of the mothers was 69.88 ± 12.06 and of the education subscale was 71.70 ± 19.97. \u0000The mean PPNCET score of the nurses and midwives was 153.50 ± 23.18. The mean care subscale score of the nurses and midwives was 73.38 ± 8.84, and the mean education subscale score was 80.11 ± 14.33. \u0000Conclusions: The mean PPNCET score of mothers and nurses and midwives were higher than the average. Higher PPNCET scores of the nurses and midwives compared to the mothers suggests that either the postpartum care given was not perceived as adequate by the mothers, or the care was not served in adequate quality. To increase postpartum care satisfaction of the mothers, involving nurses and midwives in the care process more is suggested. In line with these results, planning in-service training programs to develop the knowledge and skills of the nurses and midwives would be beneficial in increasing the quality of service","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43128844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.33808/clinexphealthsci.714950
Banu Ünver, H. Taskiran, A. Akgöl
Objective: The aim of this study was to investigate the foot muscle strength, muscle shortness, tibialis posterior endurance, balance, and the shoe preference differences between the neutral and pronated foot posture. Methods: Forty-nine participants consisting of 23 women and 26 men, and age of between 18 and 45 years were participated in the study. Foot posture, medial longitudinal arch height, height, gastrocnemius and hamstring muscle shortness, foot and ankle muscle strength, tibialis posterior muscle endurance, static balance, and shoe preferences of the participants were evaluated. Subjects were recruited into two groups according to their foot posture evaluated with Foot Posture Index: as those with neutral and pronated foot posture. Results: Navicular drop, gastrocnemius, and hamstring muscle shortness were significantly higher in participants with pronated foot posture compared to those with neutral foot (p0.05). Conclusion: Flexibility of gastrocnemius and hamstring muscles were reduced, but foot muscle strength, tibialis posterior muscle endurance, and balance remained unaffected in young individuals with excessive foot pronation. Moreover, shoe preferences may not affect the foot posture in young people. Although all age-related biomechanical effects of foot pronation are not well known yet, muscle shortness seems to arise earlier than muscle weakness and reduced balance in pronated foot posture
{"title":"Foot Muscle Strength, Muscle Shortness, Balance, and Shoe Preferences in Different Foot Postures","authors":"Banu Ünver, H. Taskiran, A. Akgöl","doi":"10.33808/clinexphealthsci.714950","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.714950","url":null,"abstract":"Objective: The aim of this study was to investigate the foot muscle strength, muscle shortness, tibialis posterior endurance, balance, and the shoe preference differences between the neutral and pronated foot posture. \u0000Methods: Forty-nine participants consisting of 23 women and 26 men, and age of between 18 and 45 years were participated in the study. Foot posture, medial longitudinal arch height, height, gastrocnemius and hamstring muscle shortness, foot and ankle muscle strength, tibialis \u0000posterior muscle endurance, static balance, and shoe preferences of the participants were evaluated. Subjects were recruited into two groups according to their foot posture evaluated with Foot Posture Index: as those with neutral and pronated foot posture. \u0000Results: Navicular drop, gastrocnemius, and hamstring muscle shortness were significantly higher in participants with pronated foot posture compared to those with neutral foot (p0.05). \u0000Conclusion: Flexibility of gastrocnemius and hamstring muscles were reduced, but foot muscle strength, tibialis posterior muscle endurance, and balance remained unaffected in young individuals with excessive foot pronation. Moreover, shoe preferences may not affect the foot posture in young people. Although all age-related biomechanical effects of foot pronation are not well known yet, muscle shortness seems to arise earlier than muscle weakness and reduced balance in pronated foot posture","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43143602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.33808/clinexphealthsci.1030132
Nuray Nükhet İmdat, Ö. T. ÇİLİNGİR-KAYA, Zehra Nur Turgan Aşık, Tugba Karamahmutoglu, Medine Gülçebi İdriz Oğlu, D. Akakın, F. Onat, S. Şirvancı
Objective: The hypotheses related to the fact of epileptic mechanisms are mainly based on excitation-inhibition imbalance in central nervous system. GAERS (Genetic Absence Epilepsy Rats from Strasbourg) is a well-known animal model of absence epilepsy, and frequently used in experimental studies. In the present study, we aimed to examine possible morphological and gamma-aminobutyric acid (GABA) density changes in GAERS hippocampus after electrical kindling stimulations. Methods: All control and test group rats received 6 kindling stimulations. Rats were decapitated 1 h after the last stimulation. Ultrastructural GABA immunocytochemistry was used to evaluate GABA density quantitatively in mossy terminals of hippocampal CA3 region. Results: GABA levels were less in kindling groups compared to their controls, and in GAERS groups compared to Wistar groups; mitochondrial and dendritic spine area ratios were greater in GAERS groups compared to Wistar groups, although all these evaluations were statistically nonsignificant. Depletion of synaptic vesicles was evident in the mossy terminals of kindling groups. Conclusion: The reason of decreased levels of GABA found in the present study might be that GABA has been released from the synaptic pool rapidly at an early time period after the last stimulation, for compansation mechanisms. Depletion of synaptic vesicles observed in kindling groups shows that even 6 kindling stimulations have an impact of changing hippocampal morphology in trisynaptic cycle. The increased mitochondrial area in GAERS might be related to the increased mitochondrial activity. The increased dendritic spine area might be related to the increased performance of learning in GAERS. Our findings indicating that absence epilepsy and temporal lobe epilepsy have different mechanisms of epileptogenesis might be a basis for further experimental studies
{"title":"Electron microscopic GABA evaluation in hippocampal mossy terminals of genetic absence epilepsy rats receiving kindling stimulations","authors":"Nuray Nükhet İmdat, Ö. T. ÇİLİNGİR-KAYA, Zehra Nur Turgan Aşık, Tugba Karamahmutoglu, Medine Gülçebi İdriz Oğlu, D. Akakın, F. Onat, S. Şirvancı","doi":"10.33808/clinexphealthsci.1030132","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1030132","url":null,"abstract":"Objective: The hypotheses related to the fact of epileptic mechanisms are mainly based on excitation-inhibition imbalance in central nervous system. GAERS (Genetic Absence Epilepsy Rats from Strasbourg) is a well-known animal model of absence epilepsy, and frequently used in experimental studies. In the present study, we aimed to examine possible morphological and gamma-aminobutyric acid (GABA) density changes in GAERS hippocampus after electrical kindling stimulations. \u0000Methods: All control and test group rats received 6 kindling stimulations. Rats were decapitated 1 h after the last stimulation. Ultrastructural GABA immunocytochemistry was used to evaluate GABA density quantitatively in mossy terminals of hippocampal CA3 region. \u0000Results: GABA levels were less in kindling groups compared to their controls, and in GAERS groups compared to Wistar groups; mitochondrial and dendritic spine area ratios were greater in GAERS groups compared to Wistar groups, although all these evaluations were statistically nonsignificant. Depletion of synaptic vesicles was evident in the mossy terminals of kindling groups. \u0000Conclusion: The reason of decreased levels of GABA found in the present study might be that GABA has been released from the synaptic pool rapidly at an early time period after the last stimulation, for compansation mechanisms. Depletion of synaptic vesicles observed in kindling groups shows that even 6 kindling stimulations have an impact of changing hippocampal morphology in trisynaptic cycle. The increased mitochondrial area in GAERS might be related to the increased mitochondrial activity. The increased dendritic spine area might be related to the increased performance of learning in GAERS. Our findings indicating that absence epilepsy and temporal lobe epilepsy have different mechanisms of epileptogenesis might be a basis for further experimental studies","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43730630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.33808/clinexphealthsci.1036428
A. Tanyeli̇, F. N. Ekinci Akdemir, E. Eraslan, M. Güler, Tuncer Nacar, S. Çomaklı, I. Gülçin
Objective: We planned to search the effects of p-coumaric acid on ovary and lung injuries formed via bilateral adnexal torsion detorsion (T/D) in experimental rat model. Methods: 24 female, Sprague-Dawley rats were sorted out as 3 groups. Design of the groups was performed as sham (group I) and T/D (group II), p-coumaric acid+T/D (group III) groups. Sham group; abdomen area was applied incision and repaired with no T/D model application. T/D group; 3 h of torsion phase completed and then 3 h of detorsion stage was established. P-coumaric acid+T/D group; p-coumaric acid was administered at the dose of 100 mg/kg for 15 days by oral gavage and then, T/D model was performed. Following detorsion phase, rats were sacrificed, lung and ovarian tissues were excised for biochemical and immunohistochemical evaluations. Results: When it is compared to group I, oxidant parameters elevated significantly in group II (p<0.05) while the activity of antioxidant enzymes and TAS level decreased. On the other side, antioxidant enzyme activity raised and oxidant parameter levels diminished in group III compared to group II (p<0.05). Moreover, NF-kB, caspase 3 and LC3B protein expression levels increased in ovary and lung tissues of the group II. But NF-kB, caspase 3 and LC3B protein expression levels decreased in group III. Conclusion: As a consequence, p-coumaric acid acted a protective performance against ovary and lung injuries arising from adnexal T/D model in rats.
{"title":"The Role of p-Coumaric Acid on Reproductive and Remote Organ Damages Created by Adnexal Torsion/Detorsion: Biochemical and Immunohistochemical A Study","authors":"A. Tanyeli̇, F. N. Ekinci Akdemir, E. Eraslan, M. Güler, Tuncer Nacar, S. Çomaklı, I. Gülçin","doi":"10.33808/clinexphealthsci.1036428","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1036428","url":null,"abstract":"Objective: We planned to search the effects of p-coumaric acid on ovary and lung injuries formed via bilateral adnexal torsion detorsion (T/D) in experimental rat model.\u0000Methods: 24 female, Sprague-Dawley rats were sorted out as 3 groups. Design of the groups was performed as sham (group I) and T/D (group II), p-coumaric acid+T/D (group III) groups. Sham group; abdomen area was applied incision and repaired with no T/D model application. T/D group; 3 h of torsion phase completed and then 3 h of detorsion stage was established. P-coumaric acid+T/D group; p-coumaric acid was administered at the dose of 100 mg/kg for 15 days by oral gavage and then, T/D model was performed. Following detorsion phase, rats were sacrificed, lung and ovarian tissues were excised for biochemical and immunohistochemical evaluations. \u0000Results: When it is compared to group I, oxidant parameters elevated significantly in group II (p<0.05) while the activity of antioxidant enzymes and TAS level decreased. On the other side, antioxidant enzyme activity raised and oxidant parameter levels diminished in group III compared to group II (p<0.05). Moreover, NF-kB, caspase 3 and LC3B protein expression levels increased in ovary and lung tissues of the group II. But NF-kB, caspase 3 and LC3B protein expression levels decreased in group III. \u0000Conclusion: As a consequence, p-coumaric acid acted a protective performance against ovary and lung injuries arising from adnexal T/D model in rats.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45578788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.33808/clinexphealthsci.1025304
Ayşenur Durmuş, Gülşen Eryilmaz
Objective: This study was carried out to determine the effects of massage and hot-pack applications in the first stage of labor on perceptions of labor pain and duration of delivery. Methods: This randomized controlled experimental trial was conducted in an obstetrics and pediatrics hospital. The research sample comprised 120 pregnant women, 40 of whom were in the massage group, 40 of whom were in the hot-pack application group, and 40 of whom were in the control group. Patient identification forms, labor process monitoring forms, and a visual analogue scale (VAS) were used to collect data. Results: It was determined that the massage and hot-pack applications shortened the durations of the active and transition phases of labor. The massage and hot-pack applications also reduced perceptions of pain in the active and transition phases. Mean VAS scores of the massage and hot-pack application groups were lower than those of the control group (p
{"title":"Effects of Heat and Massage Applications to the Lumbosacral Area on Duration of Delivery and Perception of Labor Pain: A Randomized Controlled Experimental Trial","authors":"Ayşenur Durmuş, Gülşen Eryilmaz","doi":"10.33808/clinexphealthsci.1025304","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1025304","url":null,"abstract":"Objective: This study was carried out to determine the effects of massage and hot-pack applications in the first stage of labor on perceptions of labor pain and duration of delivery. \u0000Methods: This randomized controlled experimental trial was conducted in an obstetrics and pediatrics hospital. The research sample comprised 120 pregnant women, 40 of whom were in the massage group, 40 of whom were in the hot-pack application group, and 40 of whom were in the control group. Patient identification forms, labor process monitoring forms, and a visual analogue scale (VAS) were used to collect data. \u0000Results: It was determined that the massage and hot-pack applications shortened the durations of the active and transition phases of labor. The massage and hot-pack applications also reduced perceptions of pain in the active and transition phases. Mean VAS scores of the massage and \u0000hot-pack application groups were lower than those of the control group (p","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43827403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.33808/clinexphealthsci.929352
Nuray Göker, Zümrüt Bilgin
Objective: This study aims to examine the effect of the duration of the active labor phase on postpartum fatigue and comfort. Methods: This descriptive study was conducted in a maternity hospital in Istanbul, Turkey date 2018. Nulliparous pregnant women without any risk (n: 120) participated in the study. Data were collected using the “Information Form”, the “Visual Analogue Scale”, the “Postpartum Comfort Scale” and the “Visual Analogue Scale for Fatigue”, and statistically analyzed. Results: The mean age of the women was 23.66±4.24 years. 22.5% felt very tired in the postpartum period. Their mean duration of active labor phase was 5.00±1.88 hours. Their Postpartum Comfort Scale and Visual Analogue Scale for Fatigue mean scores were 131.30±13.39 and 96.67±47.82, respectively. Conclusion: Duration of active labor phase did not affect postpartum fatigue and comfort of women
{"title":"The Effect of Duration of Active Labor Phase on Postpartum Fatigue and Comfort","authors":"Nuray Göker, Zümrüt Bilgin","doi":"10.33808/clinexphealthsci.929352","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.929352","url":null,"abstract":"Objective: This study aims to examine the effect of the duration of the active labor phase on postpartum fatigue and comfort.\u0000Methods: This descriptive study was conducted in a maternity hospital in Istanbul, Turkey date 2018. Nulliparous pregnant women without any risk (n: 120) participated in the study. Data were collected using the “Information Form”, the “Visual Analogue Scale”, the “Postpartum Comfort Scale” and the “Visual Analogue Scale for Fatigue”, and statistically analyzed.\u0000Results: The mean age of the women was 23.66±4.24 years. 22.5% felt very tired in the postpartum period. Their mean duration of active labor phase was 5.00±1.88 hours. Their Postpartum Comfort Scale and Visual Analogue Scale for Fatigue mean scores were 131.30±13.39 and 96.67±47.82, respectively.\u0000Conclusion: Duration of active labor phase did not affect postpartum fatigue and comfort of women","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45110428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.33808/clinexphealthsci.895693
N. Taner, B. Berk
Objective: Heart failure (HF), caused by an abnormality in cardiac function, is the inability of heart tissue to pump blood or deliver sufficient oxygen, resulting in abnormal diastolic volume. Drug-Related Problems (DRPs) can cause significant but preventable morbidity and mortality once specific medication errors and their contributing factors are identified. The aim of this prospective study is to determine the effect of pharmaceutical care in patients with heart failure in a Turkish hospital. Methods: A total of 160 patients with heart failure (80 patients in the control group, 80 patients in the intervention group) were examined at a university hospital. The results of the Pharmaceutical Care Survey were evaluated in accordance with the objective of the study. In addition, using the Pharmaceutical Care Network Europe (PCNE) classification system V8.01, the role and importance of the clinical pharmacist in identifying, preventing and resolving drug-related problems encountered during the treatment of two groups was assessed. The number and causes of potential DRPs were taken into scrutiny. Results: Comparing the results of the Pharmaceutical Care Survey in both groups at the end of the 6th month, the study group shows a significant improvement in the rates of “forgetting to take medication” (2.9%) and “experiencing any side effects from your drug” (4.5%). Compared to other problems, ineffectiveness of the drugs used in treatment was reported as the most common drug-related problem (n=23; 28.7%) in the study group (p
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Pub Date : 2022-12-30DOI: 10.33808/clinexphealthsci.1049382
A. Iyibozkurt, B. Çakmakoğlu, Baris Ertugrul, E. Iplik
Objective: Our study examines nuclear factor kappa B (NF-қB) and cyclooxygenase-2 (COX-2) polymorphisms in the most common gynecological cancer type, endometrial cancer, and the relationship between disease parameters and these polymorphisms. Methods: In our patient group; while 109 endometrial cancer patients were examined and treated in the Department of Gynecology and Obstetrics, Istanbul Medical Faculty, and 106 healthy women without the disease were included in the control group. DNA of blood samples taken from all groups were isolated; COX-2 765C> G and COX-2 1195A> G polymorphisms were studied with NF-қB-94 ins / delATTG. Genotypes analyzed using the PCR-based restriction fragment length polymorphisms (RFLP) method were investigated in terms of the relationship between endometrial cancer susceptibility and endometrial cancer disease parameters. Results in SPSS 17 program; Student’s t-tests were analyzed using Anova, Fisher’s exact, and Chi-square tests. Results: NF-қB D + and DD genotype, COX-2 765 G + and GG genotype, and COX-2 1195 AA genotype were found to be significantly more common in the endometrial cancer group compared to the control group (p
目的:探讨核因子κ B (NF-қB)和环氧化酶-2 (COX-2)在妇科最常见的癌症类型子宫内膜癌中的多态性及其与疾病参数的关系。方法:在本组患者中;109名子宫内膜癌患者在伊斯坦布尔医学院妇产科接受检查和治疗，106名未患病的健康妇女作为对照组。分离各组血液样本的DNA;利用NF-қB-94 ins / delATTG研究COX-2 765C> G和COX-2 1195A> G多态性。利用基于pcr的限制性片段长度多态性(RFLP)方法分析基因型，探讨子宫内膜癌易感性与子宫内膜癌疾病参数的关系。SPSS 17程序结果;学生t检验采用方差分析、费雪精确检验和卡方检验进行分析。结果:NF-қB D +和DD基因型、cox - 2765 G +和GG基因型、cox - 21195 AA基因型在子宫内膜癌组的发生率明显高于对照组(p
{"title":"NF-қB and COX-2 Relation Between Endometrial Cancer and the Clinicopathological Parameters","authors":"A. Iyibozkurt, B. Çakmakoğlu, Baris Ertugrul, E. Iplik","doi":"10.33808/clinexphealthsci.1049382","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1049382","url":null,"abstract":"Objective: Our study examines nuclear factor kappa B (NF-қB) and cyclooxygenase-2 (COX-2) polymorphisms in the most common gynecological cancer type, endometrial cancer, and the relationship between disease parameters and these polymorphisms. \u0000Methods: In our patient group; while 109 endometrial cancer patients were examined and treated in the Department of Gynecology and Obstetrics, Istanbul Medical Faculty, and 106 healthy women without the disease were included in the control group. DNA of blood samples taken from all groups were isolated; COX-2 765C> G and COX-2 1195A> G polymorphisms were studied with NF-қB-94 ins / delATTG. Genotypes analyzed using the PCR-based restriction fragment length polymorphisms (RFLP) method were investigated in terms of the relationship between endometrial cancer susceptibility and endometrial cancer disease parameters. Results in SPSS 17 program; Student’s t-tests were analyzed \u0000using Anova, Fisher’s exact, and Chi-square tests. \u0000Results: NF-қB D + and DD genotype, COX-2 765 G + and GG genotype, and COX-2 1195 AA genotype were found to be significantly more common in the endometrial cancer group compared to the control group (p","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44206974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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