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Cutaneous angiosarcoma arising over rhinophyma: an unusual variant of lymphoedema-associated angiosarcoma? 鼻赘瘤上长出的皮肤血管肉瘤:淋巴水肿相关血管肉瘤的不寻常变种?
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2024-10-24 DOI: 10.1093/ced/llae233
Michele Lanzetti, Virginia A Colantuono, Stefano Francalanci, Daniela Massi, Pietro Antonini, Vieri Grandi
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引用次数: 0
A cross-sectional analysis of TikTok content relating to sunscreen conspiracy theories and correlation with published evidence on sunscreen risks. 对 TikTok 上有关防晒霜阴谋论的内容以及与已公布的防晒霜风险证据的相关性进行横向分析。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2024-10-23 DOI: 10.1093/ced/llae456
Nicola Kearney, Marion Leahy, Maria Stanciu, Aine O'Flynn, Mary Catherine Walsh, Mary Laing
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引用次数: 0
Granulomatous secondary syphilis - 2 case reports and review of the literature. 肉芽肿性继发性梅毒--2例病例报告和文献综述。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2024-10-23 DOI: 10.1093/ced/llae448
Delwyn Zhi Jie Lim, Joel Hua-Liang Lim, Ding Yuan Wang, Tze-Wei Martin Chio

Granulomatous inflammation is usually described in association with tertiary syphilis up till recent years where there are emerging cases reporting its presence in secondary syphilis. Herein we present two patients who presented with erythematous infiltrated papules and nodules and were eventually diagnosed with granulomatous secondary syphilis, with clearance of their rashes after treatment. In this article, we highlight the important clues that point clinicians and histopathologists towards the diagnosis of syphilis compared to other similar differentials such as leprosy in reaction, cutaneous histiocytosis and lymphoma. Additionally, from literature review and own experiences, we wish to highlight that granulomatous syphilis is often palmoplantar sparing and its presence may not necessarily be a feature of immunocompromised states (e.g. human immunodeficiency virus) In this increasingly connected world, the recognition of an atypical presentation of an age-old disease in patients with different skin types needs to be underscored with close clinicopathological correlation.

肉芽肿性炎症通常被描述为与三期梅毒有关,直到近年来才有新的病例报告其存在于二期梅毒中。本文介绍了两名出现红斑浸润性丘疹和结节的患者,他们最终被诊断为肉芽肿性二期梅毒,经过治疗后皮疹消退。在本文中,我们强调了临床医生和组织病理学家诊断梅毒的重要线索,与其他类似的鉴别诊断相比,如麻风反应、皮肤组织细胞增生症和淋巴瘤。此外,根据文献综述和自身经验,我们希望强调肉芽肿性梅毒通常不出现在掌跖,它的出现不一定是免疫功能低下状态(如人类免疫缺陷病毒)的特征。 在这个联系日益紧密的世界里,需要通过密切的临床病理相关性来强调在不同皮肤类型的患者中识别一种古老疾病的非典型表现。
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引用次数: 0
Rapid Improvement in Refractory Acrodermatitis Continua of Hallopeau With Spesolimab Injection. 斯派索利单抗注射液能迅速改善哈罗波难治性持续性皮炎的症状
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2024-10-22 DOI: 10.1093/ced/llae443
Yong He, Jingshu Xiong, Mengli Zhang, Haoxiang Xu, Hao Chen
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引用次数: 0
Assessment of sun protection factors in the Irish adult population following the SunSmart Campaign 2023. 评估 "2023 年阳光明智运动 "之后爱尔兰成年人的防晒系数。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2024-10-22 DOI: 10.1093/ced/llae450
Caitriona Kelly, Maria McEnery, Selene Daly, Anne Marie Tobin, Triona McCarthy

Background: SunSmart is the National Cancer Control Programme's annual skin cancer prevention awareness campaign.

Objectives: This study aimed to assess sun protection attitudes following the 2023 campaign, and compare findings to 2022.

Methods: An online survey was conducted in September 2023, a repeat of the 2022 survey. Data were collated and analysed in Excel.

Results: In 2023, 48% (n=480) adults reported being sunburnt that summer. Younger adults were more likely than older adults to report sunburn (62% v 28% p<0.001). In assessing the "SunSmart 5s": 94% rated sunscreen, 88% rated shade, 84% rated hats, 71% rated long sleeves, and 70% rated sunglasses as important. Older adults were more likely than younger adults to rate each factor as important. A higher proportion reported each factor as important compared to 2022. Awareness of the campaign increased, 32% having heard of SunSmart, compared to 21% in 2022 (p<0.001). Awareness was higher in older adults (39% v 21% p<0.001), and in those who reported no sunburn (34% v 30% p=0.023).

Conclusions: Awareness of SunSmart and perceived importance of the sun protection factors have improved since 2022, with perceived importance of the "SunSmart 5s" reasonably high. Reaching younger adults and improving their sun protection behaviours remain areas for progress.

背景:SunSmart 是国家癌症控制计划每年开展的皮肤癌预防宣传活动:本研究旨在评估 2023 年宣传活动后的防晒态度,并将调查结果与 2022 年进行比较:方法:2023 年 9 月进行了一次在线调查,这是对 2022 年调查的重复。数据用 Excel 进行整理和分析:2023年,48%(n=480)的成年人表示在那个夏天被晒伤过。年轻人比老年人更容易被晒伤(62% 对 28%):自 2022 年以来,人们对 "阳光智护 "的认识和对防晒因素重要性的认识都有所提高,对 "阳光智护 5 要素 "重要性的认识也相当高。接触年轻成年人并改善他们的防晒行为仍是需要取得进展的领域。
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引用次数: 0
Acne-Related Quality of Life and Mental Health Among Adolescents: A Cross-Sectional Analysis. 青少年与痤疮有关的生活质量和心理健康:横断面分析
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2024-10-19 DOI: 10.1093/ced/llae453
Shireen Dumont, Elsa Lorthe, Andrea Loizeau, Viviane Richard, Mayssam Nehme, Klara M Posfay-Barbe, Rémy P Barbe, Laurence Toutous Trellu, Silvia Stringhini, Idris Guessous, Roxane Dumont

Backgrounds: Acne vulgaris is one of the most common skin conditions worldwide among adolescents. Beyond its physical manifestations, acne can leave invisible psychological scars.

Objectives: We aimed to examine the protective and risk factors of acne-related quality of life, and its association with mental health outcomes.

Methods: The analysis included data collected in 2023 from adolescents enrolled in the SEROCoV-KIDS population-based cohort. By combining the Acne Severity and Acne-Quality of Life (Acne-QoL) scales, three groups were established: Acne-LowAQoL (adolescents with acne and low Acne-related Quality of Life), Acne-HighAQoL, and NoAcne-HighAQoL. We used multinomial and logistic regression to assess the association between health behaviours, these groups, and mental health outcomes.

Results: Among 335 adolescents (mean age 16.1 years [SD 1.8], 56% female), 65 (19.4%) reported experiencing acne while maintaining a high Acne-QoL, 26 (7.7%) reported having acne and a low Acne-QoL and 244 (72.9%) reported having nearly no acne. Low engagement in physical activity (aOR: 0.30, 95% CI: 0.12-0.77), addictive use of social media (aOR: 3.78, 95%CI: 1.60-8.96), and prolonged screen time (aOR: 2.99, 95%CI: 1.26-7.08) were independently associated with Acne-LowAQoL. Conversely, those from the group Acne-HighAQoL reported higher social support (aOR: 1.95, 95%CI: 1.07-3.54). Adolescents with Acne-LowAQoL showed lower levels of self-esteem, resilience, and increased psychological distress.

Conclusions: Among adolescents with acne, physical activity and social support were positively associated with good acne-related quality of life, which translated into better mental health. In contrast, screen time and social media use notably reduced it. Dermatologists should incorporate these considerations into clinical practice to ensure effective patient care.

背景:寻常痤疮是全球青少年中最常见的皮肤病之一。除了身体上的表现外,痤疮还会在心理上留下无形的伤疤:我们旨在研究与痤疮相关的生活质量的保护因素和风险因素及其与心理健康结果的关联:分析包括 2023 年收集的 SEROCoV-KIDS 群体队列中青少年的数据。结合痤疮严重程度量表和痤疮生活质量(Acne-QoL)量表,确定了三个组别:痤疮-低生活质量量表组(患有痤疮且痤疮相关生活质量较低的青少年)、痤疮-高生活质量量表组和无痤疮-高生活质量量表组。我们使用多项式回归和逻辑回归来评估健康行为、这些组别和心理健康结果之间的关联:在 335 名青少年(平均年龄 16.1 岁 [标码 1.8],56% 为女性)中,有 65 人(19.4%)表示在长痤疮的同时保持较高的痤疮生活质量水平,26 人(7.7%)表示在长痤疮的同时保持较低的痤疮生活质量水平,244 人(72.9%)表示几乎没有长过痤疮。很少参加体育锻炼(aOR:0.30,95%CI:0.12-0.77)、沉迷于使用社交媒体(aOR:3.78,95%CI:1.60-8.96)和长时间使用屏幕(aOR:2.99,95%CI:1.26-7.08)与痤疮-低痤疮生活质量相关。相反,痤疮-高AQoL组的青少年则获得了更多的社会支持(aOR:1.95,95%CI:1.07-3.54)。痤疮-低AQoL组青少年的自尊心和抗压能力较低,心理压力也有所增加:在患有痤疮的青少年中,体育锻炼和社会支持与良好的痤疮相关生活质量呈正相关,而良好的痤疮相关生活质量又会带来更好的心理健康。相比之下,屏幕时间和社交媒体的使用则明显降低了生活质量。皮肤科医生应在临床实践中考虑到这些因素,以确保为患者提供有效的护理。
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引用次数: 0
Bipolar disorder among individuals with atopic dermatitis: A case-control study in the All of Us Research Program. 特应性皮炎患者中的躁郁症:我们所有人研究计划中的一项病例对照研究。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2024-10-19 DOI: 10.1093/ced/llae451
A Mitchel Wride, Gloria F Chen, Ryan Fan, Audrey C Leasure, S Scott Jones, Daniel F Levey, William Damsky, Jeffrey M Cohen

Background: Atopic dermatitis (AD) has been associated with psychiatric comorbidities.

Objectives: To characterize the association between AD and bipolar disorder (BPD) with a case-control study of the NIH All of Us Research Program.

Methods: Utilizing Systemized Nomenclature of Medicine diagnostic codes, we identified cases of AD. Four age, sex, and race/ethnicity matched controls were found for each case using propensity score matching. After controlling for age, sex, race/ethnicity, income, smoking status, and depression, the relationship between AD and BPD was evaluated using logistic regression.

Results: We identified 13,431 AD cases with 53,724 matched controls. Participants with AD were more likely than controls to have BPD (7.8% vs. 4.6%, P<.001). After adjusting for demographics and comorbidities, we observed a significant association (OR 1.49, 95%CI 1.37-1.62, P<.001).

Conclusion: Compared to individuals without AD, individuals with AD have 1.49-fold increased odds of having BPD. Further investigation is needed to further understand this association.

背景:特应性皮炎(AD)与精神疾病有关:特应性皮炎(AD)与精神病合并症有关:通过美国国立卫生研究院 "我们所有人 "研究项目的病例对照研究,确定特应性皮炎与双相情感障碍(BPD)之间的关系:方法:利用系统化医学术语诊断代码,我们确定了注意力缺失症病例。利用倾向得分匹配法为每个病例找到四个年龄、性别和种族/民族匹配的对照组。在对年龄、性别、种族/民族、收入、吸烟状况和抑郁进行控制后,我们使用逻辑回归法评估了 AD 与 BPD 之间的关系:结果:我们发现了 13,431 例注意力缺失症病例和 53,724 例匹配对照。与对照组相比,AD 患者更有可能患有 BPD(7.8% 对 4.6%,PC):与非 AD 患者相比,AD 患者患 BPD 的几率增加了 1.49 倍。要进一步了解这种关联,还需要进一步调查。
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引用次数: 0
Risk of Suicide and Suicidality in Patients with Moderate to Severe Psoriasis: results from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR). 中度至重度银屑病患者自杀和自杀倾向的风险:英国皮肤科医师协会生物制剂和免疫调节剂登记册(BADBIR)的结果。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2024-10-19 DOI: 10.1093/ced/llae449
Kerry Williams, Georgia Lada, Nick J Reynolds, Kathleen Mcelhone, Ian Evans, Richard B Warren, Shernaz Walton, Olivia Hughes, Anthony Bewley, Kayleigh Mason, C Elise Kleyn

Background: Psoriasis is associated with poor mental health and reduced quality of life. Although the high risk for depression in patients with psoriasis is well-established, their suicidality risk is uncertain. Previous studies provide contrasting results and have not included patients with clinically-confirmed severe disease.

Objectives: Our aim was to determine risk of suicide among patients with moderate to severe psoriasis compared with the general population, and investigate if psychiatric comorbidity or history of suicidality increases future suicidality risk in psoriasis. We further estimated the incidence of suicidal and self-injurious behaviours in patients.

Methods: Analysis was performed using the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR). As controls, general population mortality and suicide data were used.

Results: There were 9 suicides in BADBIR. The incidence rate of suicide was 12.5 per 100,000 person-years (95% CI 6.53, 24.11) in BADBIR versus 11.0 per 100,000 person-years (95% CI 10.7, 11.3) in the general population in England and Wales. Among patients, psychiatric comorbidity or past suicidality was associated with higher risk for suicidal ideation, suicide attempts and self-injurious behaviours.

Conclusions: Suicide rates among patients with moderate to severe psoriasis were not significantly higher compared with the general population. Suicide is a rare event and our results are limited by the uncertainty in the estimate reliability. However, considering the high depression prevalence in psoriasis, our findings support the need for prompt assessment of patients for psychiatric comorbidities and suicidality history. Further research is required on suicidal behaviours and the role of psoriasis severity.

背景:银屑病与心理健康状况不佳和生活质量下降有关。虽然银屑病患者患抑郁症的风险很高,但其自杀风险却不确定。以往的研究提供了截然不同的结果,而且未将临床确诊的重症患者包括在内:我们的目的是确定与普通人群相比,中重度银屑病患者的自杀风险,并调查精神疾病合并症或自杀史是否会增加银屑病患者未来的自杀风险。我们还进一步估算了患者自杀和自伤行为的发生率:使用英国皮肤科医师协会生物制剂和免疫调节剂登记册(BADBIR)进行分析。结果:英国皮肤科医师协会生物制剂和免疫调节剂登记册中有9例自杀事件:结果:BADBIR 登记了 9 起自杀事件。BADBIR的自杀发生率为每10万人年12.5例(95% CI为6.53例,24.11例),而英格兰和威尔士普通人群的自杀发生率为每10万人年11.0例(95% CI为10.7例,11.3例)。在患者中,精神疾病合并症或既往自杀倾向与较高的自杀意念、自杀未遂和自残行为风险相关:结论:与普通人群相比,中重度银屑病患者的自杀率并没有明显升高。自杀是一种罕见的事件,我们的结果受到估计可靠性不确定性的限制。不过,考虑到银屑病患者中抑郁症发病率较高,我们的研究结果支持有必要及时评估患者的精神并发症和自杀史。关于自杀行为和银屑病严重程度的作用,还需要进一步研究。
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引用次数: 0
General Dermatology and Dermatology in Primary Healthcare. 普通皮肤病学和初级保健中的皮肤病学。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2024-10-19 DOI: 10.1093/ced/llae454
Jonathan E Sutton, Usama Qureshi, Samantha Body, Richard Byrom, Nicholas White, Adrian C Bateman, Ian C Pearson
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引用次数: 0
Unilateral heliotrope rash: first sign of paraneoplastic anti-TIF1γ dermatomyositis. 单侧日光疹:副肿瘤性抗TIF1γ皮肌炎的首发症状。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2024-10-19 DOI: 10.1093/ced/llae445
Sofia Antunes-Duarte, Dora Mancha, Cláudia Brazão, Lanyu Sun, Roberto Pereira da Costa, Raquel Campanilho-Marques, José Carlos Romeu, Tiago Santos, Pedro de Vasconcelos, Luís Soares-de-Almeida, Paulo Filipe
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引用次数: 0
期刊
Clinical and Experimental Dermatology
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