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Letter to the Editor: Standardized Intraoperative Robotic Laxity Assessment in TKA Leads to No Clinically Important Improvements at 2 Years Postoperatively: A Randomized Controlled Trial. 致编者信:一项随机对照试验:术后2年,TKA中标准化的术中机器人松弛度评估没有导致重要的临床改善。
IF 4.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-01 Epub Date: 2025-10-09 DOI: 10.1097/CORR.0000000000003636
Chia-Hao Hsu
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引用次数: 0
Compensatory Activation of Periscapular Muscles Aids Active Abduction in Patients With Massive Rotator Cuff Tears. 肩胛周围肌的代偿性激活有助于大量肩袖撕裂患者的主动外展。
IF 4.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-01 Epub Date: 2025-05-28 DOI: 10.1097/CORR.0000000000003556
Hao-Chun Chuang, Nan-Tsing Chiu, Zhao-Wei Liu, Chih-Kai Hong, Kai-Lan Hsu, Fa-Chuan Kuan, Yueh Chen, Joe-Zhi Yen, Wei-Ren Su
<p><strong>Background: </strong>Patients with massive rotator cuff tears can present with shoulder pain with preserved ROM, yet the compensatory mechanisms remain poorly understood. Identifying these mechanisms, particularly the role of periscapular muscles, could guide nonsurgical therapeutic strategies.</p><p><strong>Questions/purposes: </strong>(1) In patients with massive rotator cuff tears who achieved acceptable active ROM with physical therapy, which periscapular muscles provide compensatory motor activity? (2) What is the correlation between muscle metabolic activity and fatty infiltration and atrophy?</p><p><strong>Methods: </strong>Between January 2019 and April 2019, we evaluated 39 consecutive patients who presented to our outpatient clinic and were diagnosed with massive rotator cuff tears through sonographic screening. Of these, 41% (16) were excluded because of concomitant diseases. Of the remaining 59% (23) of patients who met the inclusion criteria and began the rehabilitation program, 13% (5) discontinued because of partial adherence or conversion to surgery. Ultimately, 46% (18) of patients completed the rehabilitation program and were included in the final analysis, comprising 8 with anterosuperior tears (median [IQR] age 56 years [54 to 61]) and 10 with posterosuperior tears (median [IQR] age 59 years [58 to 64]). Additionally, four nuclear medicine technicians without a history of shoulder injury or pain were recruited as the control group (median [IQR] age 54 years [52 to 56]). To address our first research question-identifying the muscles responsible for compensatory motor activity after a massive rotator cuff tear-participants underwent positron emission tomography/CT with fluorodeoxyglucose (FDG-PET/CT) imaging after performing a scaption exercise to assess muscle metabolic activity. Standardized uptake values (SUVs), reflecting glucose-based metabolic activity, were calculated for the periscapular, rotator cuff, and deltoid muscles using FDG-PET/CT and compared among groups using Kruskal-Wallis tests. To address the second research question-examining the correlation between muscle metabolic activity and fatty infiltration or atrophy-MRI was used to assess the Goutallier classification and occupation ratio, and Spearman correlation analysis was performed to evaluate their relationship with SUVs. Continuous variables were expressed as median and IQR.</p><p><strong>Results: </strong>In patients with posterosuperior rotator cuff tears who regained acceptable active ROM, several periscapular muscles exhibited increased activity after shoulder abduction exercises compared with controls. This pattern was not observed in those with anterosuperior tears. SUVs were significantly higher in the posterosuperior group than in controls for the levator scapulae (0.75 [95% confidence interval (95% CI) 0.73 to 0.81] versus 0.65 [95% CI 0.60 to 0.71], mean rank difference 9.33; p = 0.04), rhomboids (0.80 [95% CI 0.70 to 0.85] versus 0.65
背景:大量肩袖撕裂的患者可表现为保留ROM的肩痛,但代偿机制尚不清楚。确定这些机制,特别是肩胛周围肌肉的作用,可以指导非手术治疗策略。问题/目的:(1)在通过物理治疗获得可接受的活动性ROM的大量肩袖撕裂患者中,哪些肩胛周围肌肉提供代偿性运动活动?(2)肌肉代谢活动与脂肪浸润、萎缩有何关系?方法:在2019年1月至2019年4月期间,我们评估了39例连续到我们门诊就诊并通过超声筛查诊断为大量肩袖撕裂的患者。其中41%(16例)因合并疾病而被排除。在其余59%(23)名符合纳入标准并开始康复计划的患者中,13%(5)名因部分坚持或转为手术而停止治疗。最终,46%(18)例患者完成了康复计划并纳入最终分析,其中8例为上前撕裂(中位[IQR]年龄56岁[54 ~ 61岁]),10例为上后撕裂(中位[IQR]年龄59岁[58 ~ 64岁])。此外,招募4名无肩伤或疼痛史的核医学技术人员作为对照组(中位[IQR]年龄54岁[52至56岁])。为了解决我们的第一个研究问题——确定大规模肩袖撕裂后负责代偿性运动活动的肌肉,参与者在进行截肢运动以评估肌肉代谢活动后接受了含氟脱氧葡萄糖的正电子发射断层扫描/CT (FDG-PET/CT)成像。使用FDG-PET/CT计算肩胛周围肌、肩袖肌和三角肌的标准化摄取值(SUVs),反映基于葡萄糖的代谢活动,并使用Kruskal-Wallis测试比较各组之间的差异。为了解决第二个研究问题-检查肌肉代谢活动与脂肪浸润或萎缩之间的相关性-使用mri评估Goutallier分类和职业比,并使用Spearman相关分析评估它们与suv的关系。连续变量用中位数和IQR表示。结果:与对照组相比,肩外展锻炼后,后上肩袖撕裂患者恢复可接受的活动ROM,几个肩胛周围肌肉的活动增加。这种模式在前上撕裂的患者中没有观察到。肩胛提肌的suv在后优组显著高于对照组(0.75[95%可信区间(95% CI) 0.73 ~ 0.81]对0.65 [95% CI 0.60 ~ 0.71],平均等级差9.33;p = 0.04),菱形体(0.80 [95% CI 0.70 ~ 0.85]对0.65 [95% CI 0.62 ~ 0.68],平均等级差9.58;p = 0.03),胸大肌(0.54 [95% CI 0.49 ~ 0.55] vs . 0.47 [95% CI 0.40 ~ 0.51],平均等级差6.58;p = 0.04),大圆肌(0.62 [95% CI 0.55 ~ 0.75]对0.51 [95% CI 0.47 ~ 0.55],平均等级差9.28;P = 0.03)。在前优组,仅大圆肌的SUV显著高于对照组(0.63 [95% CI 0.55 ~ 0.69]对0.51 [95% CI 0.47 ~ 0.55],平均等级差8.69;P = 0.04)。在大量肩袖撕裂恢复可接受的活动ROM的患者中,更大的脂肪浸润和更低的占比-反映更严重的肌肉萎缩-与肌肉激活减少有关。脂肪浸润与SUV呈正相关(ρ = -0.531 [95% CI -0.805 ~ -0.071];p = 0.02),职业比例与SUV之间(ρ = 0.493 [95% CI 0.018 ~ 0.786];P = 0.04)在冈上肌,但在其他肩袖肌中没有。结论:大量肩袖撕裂患者经物理治疗后外展ROM恢复,可观察到肩胛周围肌的代偿性激活。肩胛骨提升器和偏心肱骨头减压器的代谢活动增加表明它们可能有助于这种功能适应。临床相关性:基于这些发现,未来的研究可能会探索特异性针对肩胛周围肌激活的物理治疗方案是否可以提高非手术治疗的大量肩袖撕裂患者的功能结局。
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引用次数: 0
Can Simple Changes in Splinting Technique Reduce Posterior Heel Contact Pressure? 简单改变夹板技术可以减少后脚跟接触压力吗?
IF 4.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-01 Epub Date: 2025-08-21 DOI: 10.1097/CORR.0000000000003662
Erik R Nakken, Kempland C Walley, Carol A Janney, Davin C Gong, Vandan D Patel, David M Walton, Paul G Talusan, James R Holmes
<p><strong>Background: </strong>Lower extremity splints are commonly used for the treatment of foot and ankle injuries and carry the risk of posterior heel pressure injury. Assessing heel contact pressures in a splint may guide clinicians toward specific splint designs that are associated with lower contact pressures.</p><p><strong>Questions/purposes: </strong>This biomechanical study tested multiple splint characteristics to answer: (1) Which combination of heel position, padding thickness, and padding type (brand) minimizes posterior heel contact pressure? (2) Are there factors while making a splint that are associated with higher contact pressures?</p><p><strong>Methods: </strong>Twenty legs in 10 volunteer participants (mean ± SD age 30 ± 14 years) without current foot or ankle injury were recruited for this biomechanical study. Three of 10 volunteers were female. A pressure transducer was used over the posterior heel to measure contact pressure in a short leg splint. To answer our first research question about the effects of different splint characteristics, we measured contact pressures with 0, 2, 4, 6, 8, and 10 layers of two undercast padding brands, with both resting the heel down and floating the heel freely by placing the leg on a pillow to keep the splinted heel free of contact. Pressures were compared with a threshold of 32 mm Hg, the pressure of dermal arteriolar capillary collapse. To answer our second research question about factors associated with higher contact pressures, we recorded measurements of abnormal pressure spikes and observed the effect of improperly bunched or folded padding behind the heel.</p><p><strong>Results: </strong>Mean contact pressure remained above 32 mm Hg when resting the heel down, independent of padding thickness or brand. Floating the heel, by resting the leg on a pillow, with 6, 8, and 10 layers of thicker undercast padding or 8 and 10 layers of thinner padding reduced pressure below the threshold of 32 mm Hg. The mean contact pressure between 8 and 10 layers of padding was not different (10 layers reduced contact pressure by 4 mm Hg more than 8 layers [95% confidence interval -3 to 11]; p = 0.22). Improperly bunched undercast padding behind the heel increased mean contact pressure roughly threefold compared with evenly applied padding (median 270% increase [range 187% to 575%]).</p><p><strong>Conclusion: </strong>In this study, the best splint configuration consisted of 8 or 10 evenly applied layers of thicker undercast padding when floating the heel. Lower extremity positioning with the heel floating freely appears to be an important modifiable factor to reduce heel dermal pressures. We contend that attention to these details of splint application might reduce the likelihood of pressure ulcers in patients, but future clinical studies of patients with various injuries or other indications for splinting are warranted.</p><p><strong>Clinical relevance: </strong>These findings may be relevant to orthop
背景:下肢夹板常用于足部和踝关节损伤的治疗,但存在后脚跟压迫损伤的风险。评估夹板中的后跟接触压力可以指导临床医生设计与较低接触压力相关的特定夹板。问题/目的:这项生物力学研究测试了多种夹板特性,以回答:(1)哪种鞋跟位置、填充物厚度和填充物类型(品牌)的组合能最大限度地减少后跟接触压力?(2)在制作夹板时,是否存在与较高接触压力相关的因素?方法:10名没有当前足部或踝关节损伤的志愿者(平均±SD年龄30±14岁)的20条腿被招募参加这项生物力学研究。10名志愿者中有3名是女性。在短腿夹板后脚跟处使用压力传感器来测量接触压力。为了回答我们的第一个研究问题,即不同夹板特性的影响,我们测量了两种衬垫品牌的0、2、4、6、8和10层的接触压力,同时将脚后跟放下,并通过将腿放在枕头上自由浮动脚跟,以保持夹板后跟不接触。比较压力阈值为32 mm Hg时,皮肤小动脉毛细血管塌陷的压力。为了回答我们的第二个研究问题,即与较高的接触压力相关的因素,我们记录了异常压力峰值的测量结果,并观察了不正确地束在脚跟后面或折叠垫的影响。结果:当足跟向下放置时,平均接触压力保持在32毫米汞柱以上,与填充物厚度或品牌无关。通过将腿放在枕头上,使足跟漂浮,6层、8层、10层较厚的衬垫或8层、10层较薄的衬垫将压力降低到32 mm Hg以下。8层和10层衬垫之间的平均接触压力没有差异(10层衬垫比8层衬垫减少了4 mm Hg[95%置信区间-3至11];p = 0.22)。与均匀使用填充物相比,不适当地束在脚跟后面的衬垫使平均接触压力增加了大约三倍(中位数增加了270%[范围为187%至575%])。结论:在本研究中,最好的夹板配置是在浮跟时均匀地应用8或10层较厚的下垫。下肢定位与脚跟自由浮动似乎是一个重要的修改因素,以减少脚跟皮肤压力。我们认为,关注夹板应用的这些细节可能会减少患者发生压疮的可能性,但未来对各种损伤或其他适应症夹板患者的临床研究是有必要的。临床意义:这些发现可能与骨科医生、急诊科和初级保健提供者以及石膏技术人员有关,他们都在减轻足部和踝关节损伤患者医源性后脚跟压疮的机械因素方面发挥作用。
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引用次数: 0
Editorial: Fully Compromised, but Thanks All the Same to Our Peer Reviewers. 社论:完全妥协,但同样感谢我们的同行审稿人。
IF 4.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-01 Epub Date: 2025-11-07 DOI: 10.1097/CORR.0000000000003723
Seth S Leopold
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引用次数: 0
CORR Insights®: Does the Use of a Robotic Gap-tensioning System Improve Functional Outcomes After TKA? A Randomized Clinical Trial. CORR Insights®:机器人间隙张紧系统的使用是否能改善TKA后的功能结果?一项随机临床试验。
IF 4.2 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-26 DOI: 10.1097/corr.0000000000003784
Nicholas J Giori
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引用次数: 0
CORR Insights®: Which Analgesic Should We Use to Relieve Pain After Knee or Hip Arthroplasty? A Systematic Review and Network Meta-analysis of RCTs. CORR Insights®:我们应该使用哪种镇痛药来缓解膝关节或髋关节置换术后的疼痛?随机对照试验的系统回顾和网络荟萃分析。
IF 4.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-26 DOI: 10.1097/CORR.0000000000003781
Julia Blackburn
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引用次数: 0
Periacetabular Resection for Bone Tumors: Is There Still a Role for Massive Allograft-prosthesis Composite Reconstructions? 髋臼周围骨肿瘤切除术:大量同种异体移植物-假体复合重建是否仍有作用?
IF 4.2 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-25 DOI: 10.1097/corr.0000000000003754
Roberto Scanferla,Sreeraj Rajan,Federico Scolari,Luigi Maccauro,Francesco Muratori,Guido Scoccianti,Giovanni Beltrami,Domenico Andrea Campanacci
BACKGROUNDAllograft-prosthesis composite reconstruction after periacetabular resections allows for bony union and internal repair, restoring bone stock for further revisions; the allograft-prosthesis composite can be shaped according to the pelvic resection to reconstruct the complex bone anatomy. Recently, endoprosthetic reconstruction has become one of the most frequently used options to restore large periacetabular bone defects. However, a prosthetic reconstruction impairs pelvic bone stock preservation and often takes a long time to manufacture. Allograft reconstructions, on the other hand, allow for bony union and internal repair, and they restore bone stock for further revisions. In addition, allografts are usually readily available and can be shaped according to the pelvic resection, fully restoring the complex bone anatomy. Pelvic biological reconstructions may have still a role, and to our knowledge, there are few long-term results of allograft-prosthesis composite reconstruction of the pelvis after periacetabular resections for bone tumors.QUESTIONS/PURPOSES(1) What is the cumulative incidence percentage of patients who experienced complications after reconstruction with allograft-prosthesis composites after resection of periacetabular tumors? (2) What was the functional result after surgical treatment as assessed by the Musculoskeletal Tumor Society (MSTS) score at a minimum of 2 years? (3) What was the survivorship of these reconstructions free from revision and graft removal at 15 years?METHODSBetween February 1994 and April 2023, a total of 174 patients were treated at the university hospital of Florence for primary and secondary malignant or aggressive benign bone tumors of the pelvis with en bloc resection. Of treated patients, 51 underwent periacetabular resection and allograft-prosthesis composite reconstruction. We included in the study only patients with at least 24 months of follow-up or those who had complications earlier; thus 96% (49 of 51) of the patients had the required minimum follow-up and were included. Among the included patients, 88% (43 of 49) were available for a minimum follow-up of 24 months, whereas 12% (6) had < 24 months of follow-up but had complications earlier; thus, they were included for the analysis of complication-free survivorship. Seventy-eight percent (38) of patients were treated with a pelvic allograft combined with an acetabular cage, 16% (8) of patients received only a cemented cup, and 6% (3) of patients received a stemmed cementless cup. The mean ± SD follow-up time was 100 ± 77 months. The mean ± SD age at the time of reconstruction was 47 ± 17 years; 37% (18 of 49) of patients were female and 63% (31) were male. According to the Enneking and Dunham classification of pelvic resections, 39% (19) of patients had a Type I-II resection, 24% (12) had a Type II, 22% (11) had a Type II-III, 8% (4) had a Type I-II-III, 4% (2) had a Type I-II-IV, and 2% (1) had a Type I-II-III-IV. All patients had pr
背景:髋臼周围切除术后同种异体移植物-假体复合重建允许骨愈合和内部修复,为进一步翻修恢复骨储备;同种异体假体复合材料可根据骨盆切除情况进行整形,重建复杂的骨解剖结构。近年来,假体内重建已成为修复髋臼周围大面积骨缺损最常用的方法之一。然而,假体重建会损害骨盆骨储备的保存,并且通常需要很长时间来制造。另一方面,同种异体移植重建允许骨愈合和内部修复,并为进一步的翻修恢复骨存量。此外,同种异体移植物通常很容易获得,并且可以根据骨盆切除术进行塑形,充分恢复复杂的骨骼解剖结构。骨盆生物重建可能仍然有作用,据我们所知,髋臼周围骨肿瘤切除术后骨盆同种异体移植物-假体复合重建的长期结果很少。问题/目的(1)髋臼周围肿瘤切除术后同种异体移植物-假体复合材料重建术后并发症的累积发生率是多少?(2)根据肌肉骨骼肿瘤协会(MSTS)评分评估,手术治疗后至少2年的功能结果如何?(3)这些重建术后15年不进行翻修和移植物切除的存活率如何?方法1994年2月至2023年4月,在佛罗伦萨大学医院接受骨盆原发性和继发性恶性或侵袭性良性骨肿瘤全切除术的患者174例。在接受治疗的患者中,51例接受了髋臼周围切除术和同种异体假体复合重建。我们只纳入了随访至少24个月的患者或早期有并发症的患者;因此,96%(51例中的49例)的患者进行了所需的最低随访并被纳入研究。在纳入的患者中,88%(49例中的43例)的最低随访时间为24个月,而12%(6例)的随访时间< 24个月,但更早出现并发症;因此,他们被纳入无并发症生存分析。78%(38)的患者接受骨盆异体移植联合髋臼保持器,16%(8)的患者仅接受骨水泥杯,6%(3)的患者接受无骨水泥杯。平均±SD随访时间为100±77个月。重建时的平均±SD年龄为47±17岁;其中女性占37%(18 / 49),男性占63%(31 / 49)。根据Enneking和Dunham对骨盆切除术的分类,39%(19)的患者进行了I-II型切除术,24%(12)的患者进行了II型切除术,22%(11)的患者进行了II- iii型切除术,8%(4)的患者进行了I-II- iii型切除术,4%(2)的患者进行了I-II- iv型切除术,2%(1)的患者进行了I-II- iii - iv型切除术。所有患者均有原发性或继发性恶性或良性侵袭性骨肿瘤;高级别中枢性软骨肉瘤(39% [19 / 49]),Ewing肉瘤(14%[7]),高级别骨肉瘤(10%[5]),癌转移(10%[5]),去分化软骨肉瘤(10%[5]),外周低级别软骨肉瘤(2%[1]),骨巨细胞瘤(2%[1]),成骨细胞瘤(2%[1]),骨血管内皮瘤(2%[1]),未分化多形性骨肉瘤(2%[1]),骨周围神经鞘恶性肿瘤(2%[1]),辐射诱导肉瘤(2% [1]),或单发浆细胞瘤(2%)。主要并发症的累积发生率,定义为机械并发症和/或手术治疗或未手术治疗的任何重建部件的手术翻修,以及异体移植物切除作为失败的终点,分别根据竞争风险法进行估计。通过修订临床图表评估并发症。在主要感兴趣的事件之前死亡被认为是一个竞争事件。通过Gray检验比较患者亚组间的累积发病率曲线。变量的正态性采用Shapiro-Wilk检验,异方差采用Levene检验。因此,使用Welch t检验比较各组术后功能结局。每个小区报告组均值。功能评分与随访时间的关系采用Pearson相关系数确定。p < 0.05为显著性。使用MSTS评分评估功能结果。在最后一次临床随访中保留盆腔同种异体移植物的患者,随访至少2年,评估MSTS评分。通过审查我们的机构数据库来评估功能结果。 结果5年主要并发症的累计发生率为24%(95%可信区间[CI] 13% ~ 37%), 10年和15年的累计发生率为33%(95%可信区间[CI] 20% ~ 46%)。术后10±6年,平均±SD MSTS评分为23±5分。5年和10年的累计移植物切除发生率为8% (95% CI 3%至18%),15年的累计移植物切除发生率为12% (95% CI 4%至24%)。结论在3d打印时代,同种异体移植假体复合材料可能是髋臼周围骨肿瘤切除术后一种有效的重建选择;对于那些因肿瘤而没有接受化疗或放疗并且髂翼被完全或部分保留的寿命较长的患者,它仍然可以发挥作用。比较髋臼周围同种异体假体复合材料与其他重建选择(如模块化和定制的内假体,以及可回收的自体移植假体复合材料)的更大规模研究是有必要的,以评估一种技术相对于另一种技术的潜在益处。证据等级:IV级,治疗性研究。
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引用次数: 0
CORR Insights®: Only Nine Percent of Orthopaedic Clinical Trials Report and One Percent Analyze a Social Determinant of Health: A Systematic Review. CORR Insights®:只有9%的骨科临床试验报告和1%分析健康的社会决定因素:系统回顾。
IF 4.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-25 DOI: 10.1097/CORR.0000000000003778
Kacy Peek
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引用次数: 0
Do Functional Patient-reported Outcome Measures Reflect the Activities That Matter Most to Patients After Hip or Knee Arthroplasty? 功能性患者报告的结果测量是否反映了髋关节或膝关节置换术后对患者最重要的活动?
IF 4.2 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-24 DOI: 10.1097/corr.0000000000003767
Motahareh Karimijashni,Marie Westby,Paul E Beaulé,Tim Ramsay,Stéphane Poitras
BACKGROUNDAlthough there has been increasing focus on patient-centered approaches in outcome evaluation, there is limited information on how well the existing patient-reported outcome measures (PROMs) used to assess function for hip or knee arthroplasty align with patients' perspectives.QUESTIONS/PURPOSES(1) To what extent do currently used functional PROMs for hip or knee arthroplasty cover the functional activities that are important to patients at 2, 6, 13, and 26 weeks after surgery? (2) Which functional activities important to patients are either not covered or inadequately covered by PROMs? (3) Which activities not important to patients are covered by PROMs?METHODSWe assessed functional key activity coverage and coverage gaps of 47 PROMs at four points. This analysis was based on 22 key activities identified by 953 patients who underwent primary elective hip or knee arthroplasty performed by eight surgeons. These patients were recruited from the Orthopedic Division at The Ottawa Hospital in Ottawa, Ontario, Canada, an academic-affiliated institution in an urban setting. From November 2023 to March 2024 and September 2024 to January 2025, a total of 615 patients who underwent hip arthroplasty and 555 who underwent knee arthroplasty were approached, and 503 and 450, respectively, completed the questionnaire. Patients who underwent hip arthroplasty had a mean ± SD age of 65 ± 11 years; 51.1% (257 of 503) were female, and the mean BMI was 28.3 ± 5.6 kg/m2. Patients who underwent knee arthroplasty had a mean age of 68 ± 9 years; 51.3% (231 of 450) were female, and the mean BMI was 31.1 ± 6.4 kg/m2. A functional activity was defined as key if at least 75% of patients rated it as important and at least 15% had difficulty doing it.RESULTSNo PROM adequately addressed all key activities. Within the first 2 weeks after surgery, knee-specific, hip-specific, and combined hip and knee PROMs addressed 86%, 85%, and 79% of key activities, respectively, but this coverage declined for hip and knee PROMs at subsequent follow-up points to fewer than one-half by 26 weeks. The most commonly covered activities were going up and down stairs, rising from a chair, and putting on footwear. The Knee Injury and Osteoarthritis Outcome Score (KOOS) and the Hip Disability and Osteoarthritis Outcome Score (HOOS) demonstrated the widest coverage among knee and hip PROMs, respectively, while the WOMAC provided the widest coverage for combined hip and knee PROMs. Several key functional activities were either inadequately covered or not covered by PROMs. Inadequate coverage often resulted from combining multiple activities into a single item, with the most frequent key activities inadequately addressed being "going up and down stairs" and "doing housework." Five key activities, including washing lower body parts, putting on clothes, taking off clothes, carrying objects, and placing objects on the floor, were not covered by any PROMs. Furthermore, all PROMs included at least on
背景:尽管人们越来越关注以患者为中心的结果评估方法,但现有的用于评估髋关节或膝关节置换术功能的患者报告结果测量(PROMs)与患者观点的一致性信息有限。(1)目前用于髋关节或膝关节置换术的功能性PROMs在多大程度上涵盖了术后2、6、13和26周对患者重要的功能活动?(2)哪些对患者重要的功能活动在PROMs中没有涵盖或没有充分涵盖?(3)哪些对患者不重要的活动是由prom所涵盖的?方法从4个点对47个prom的功能关键活动覆盖率和覆盖率缺口进行评估。该分析基于953名患者的22项关键活动,这些患者接受了8名外科医生的原发性择期髋关节或膝关节置换术。这些患者来自加拿大安大略省渥太华的渥太华医院骨科,这是一家位于城市环境中的学术附属机构。从2023年11月至2024年3月和2024年9月至2025年1月,共接触615例髋关节置换术患者和555例膝关节置换术患者,分别有503例和450例患者完成了问卷调查。接受髋关节置换术的患者平均±SD年龄为65±11岁;51.1%(257 / 503)为女性,平均BMI为28.3±5.6 kg/m2。接受膝关节置换术的患者平均年龄为68±9岁;51.3%(231 / 450)为女性,平均BMI为31.1±6.4 kg/m2。如果至少75%的患者认为某项功能活动重要,且至少15%的患者认为该功能活动难以完成,则该功能活动被定义为关键。结果没有PROM充分处理所有关键活动。在手术后的前两周内,膝关节特异性、髋关节特异性和髋关节和膝关节联合PROMs分别解决了86%、85%和79%的关键活动,但在随后的随访中,髋关节和膝关节PROMs的覆盖率下降到26周时不到一半。最常见的活动是上下楼梯,从椅子上站起来,穿鞋。膝关节损伤和骨关节炎结局评分(oos)和髋关节残疾和骨关节炎结局评分(HOOS)分别在膝关节和髋关节PROMs中覆盖范围最广,而WOMAC在髋关节和膝关节合并PROMs中覆盖范围最广。一些关键的功能活动要么没有被充分地覆盖,要么没有被prom覆盖。不充分的覆盖通常是由于将多个活动合并到一个项目中,而最常见的关键活动是“上下楼梯”和“做家务”。清洗下半身、穿衣服、脱衣服、拿东西、把东西放在地板上这五个关键活动,没有被任何prom覆盖。此外,所有prom都至少包含一个非键活动。结论PROMs在评价治疗效果方面的作用有限,可能导致干预措施评估不准确,可能导致医疗服务的过度使用或使用不足。此外,在这些措施中包括非关键活动可能会增加患者的负担并增加无反应的可能性。为了解决这些问题,未来开发用于髋关节和膝关节置换术的PROMs应优先考虑让患者参与设计过程。临床相关性我们的研究结果表明,当前prom的长度和覆盖范围之间的关系通常是相反的。在较长和较短的prom之间进行选择需要权衡全面性和负担,最有效的prom最大限度地覆盖关键活动,同时最大限度地减少非关键活动。临床医生应该考虑在髋关节或膝关节置换术后的特定恢复阶段选择PROMs,而不是依赖于所有时间段的单一工具。这种方法可以提高随访评估的相关性,更好地支持个性化护理决策。各种各样可用的PROMs提出了选择的挑战,利益相关者,包括临床医生,患者和决策者,应该努力达成共识的一套核心结果措施,适用于不同的恢复阶段。
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What Factors and Patient-reported Outcome Measures Are Associated With Stress Fracture After Periacetabular Osteotomy? 髋臼周围截骨术后应力性骨折与哪些因素和患者报告的预后指标相关?
IF 4.2 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-24 DOI: 10.1097/corr.0000000000003744
Olivia M Jochl,Zachary A Trotzky,Giulia Beltrame,Brian T Muffly,Ernest L Sink
BACKGROUNDAlthough periacetabular osteotomy (PAO) is a commonly used procedure with generally good intermediate and long-term outcomes, complications such as stress fractures of the ischium or pubis have been reported. A limited number of studies have investigated stress fracture after PAO, but the results lack consensus and do not thoroughly explore lifestyle factors or patient-reported outcome measures (PROMs).QUESTIONS/PURPOSESAmong patients treated with PAO: (1) What percentage of patients and hips developed a stress fracture after PAO? (2) What preoperative and intraoperative factors were associated with stress fractures? (3) Did PROMs or the minimum clinically important difference (MCID) and the patient acceptable symptom state (PASS) achievement differ between patients with stress fractures and patients without at most recent follow-up?METHODSSix hundred seventy-five hips (546 patients) were treated with PAO with or without hip arthroscopy for symptomatic acetabular dysplasia between February 2016 and October 2024 by one surgeon in a mature hip preservation practice. Patients were excluded if the index procedure for those who had bilateral PAOs occurred before the study period. Patients who underwent concomitant femoral osteotomy, surgical hip dislocation, or relative neck lengthening were also excluded, yielding 90% (608 of 675) of hips from 487 patients as potentially eligible for analysis. Ninety-four percent (574 of 608) of PAOs were performed in women, and 65% (396 of 608) were performed without concomitant hip arthroscopy. The mean ± SD age was 26 ± 8 years, and the mean BMI was 23.2 ± 3.9 kg/m2. All hips had 6-week, 3-month, and 6-month postoperative radiographs available for review. Two patients with stress fractures and one without converted to THA, leaving 81% (393 of 484) of patients with available minimum 1-year PROMs after their most recent PAO surgery. Stress fracture diagnoses were tallied by hip and by patient to establish the percentages. Exploratory analyses included age, BMI, preoperative vitamin D levels, magnitude of lateral center-edge angle (LCEA) correction, magnitude of anterior center-edge angle correction, Tönnis grade, sex, marijuana use, nicotine use, screw type, prior ipsilateral surgery, PAO with or without concomitant hip arthroscopy, initial PAO versus subsequent contralateral PAO, and diagnoses of Ehlers-Danlos syndrome (EDS) or hypermobility. Factors with p < 0.1 were considered in the multivariate analysis. To determine the association between stress fractures and postoperative outcomes, univariate regression was performed with the presence of stress fractures as the independent variable. Multivariate regressions were performed to determine whether stress fractures were associated with modified Harris hip score (mHHS) and International Hip Outcome Tool-12 (iHOT-12) improvement after controlling for factors identified in the previous analysis. Similarly, regression models were used to determine whether st
背景:虽然髋臼周围截骨术(PAO)是一种常用的手术,通常具有良好的中期和长期疗效,但也有报道称其并发症,如坐骨或耻骨应力性骨折。有限数量的研究调查了PAO后的应力性骨折,但结果缺乏共识,并且没有彻底探索生活方式因素或患者报告的结果测量(PROMs)。问题/目的在接受PAO治疗的患者中:(1)PAO后发生应力性骨折的患者和髋关节的百分比是多少?(2)哪些术前和术中因素与应力性骨折相关?(3)应力性骨折患者与非应力性骨折患者的PROMs或最小临床重要差异(MCID)和患者可接受症状状态(PASS)成就是否存在差异?方法在2016年2月至2024年10月期间,一名外科医生在成熟的髋关节保存实践中对675例髋关节(546例患者)进行PAO治疗,伴有或不伴有髋关节镜检查。如果双侧PAOs患者的指标手术在研究期间之前发生,则排除患者。同时行股骨截骨术、手术髋关节脱位或相对颈部延长术的患者也被排除在外,487例患者中有90%(675例中有608例)的髋关节可能符合分析条件。94%(574 / 608)的PAOs是在女性中进行的,65%(396 / 608)的PAOs没有同时进行髋关节镜检查。平均±SD年龄为26±8岁,平均BMI为23.2±3.9 kg/m2。所有髋部术后6周、3个月和6个月的x线片可供回顾。2例患者发生应力性骨折,1例未转为THA,在最近一次PAO手术后,有81%(484例中的393例)的患者可获得至少1年的prom。应力性骨折诊断按髋部和患者进行统计,以确定百分比。探索性分析包括年龄、BMI、术前维生素D水平、外侧中心棱角(LCEA)矫正幅度、前中心棱角矫正幅度、Tönnis分级、性别、大麻使用、尼古丁使用、螺钉类型、既往同侧手术、PAO伴或不伴髋关节镜检查、初始PAO与后续对侧PAO、ehers - danlos综合征(EDS)或活动过度的诊断。多因素分析考虑p < 0.1的因素。为了确定应力性骨折与术后预后之间的关系,以应力性骨折为自变量进行单变量回归。在控制先前分析中确定的因素后,进行多变量回归以确定应力性骨折是否与改良Harris髋关节评分(mHHS)和国际髋关节预后工具-12 (iHOT-12)改善相关。同样,回归模型用于确定应力裂缝是否与MCID和PASS的实现相关。结果应力性骨折发生率为8%(487例中37例),髋部发生率为7%(608例中40例)。在接受双侧PAOs的患者中,11%(121例中的13例)在第二次手术后发生应力性骨折。121例患者中有3例(2%)发生双侧应力性骨折。在控制了潜在的混杂变量,如年龄、BMI、LCEA矫正、药物使用、EDS或过度活动后,我们发现有几个因素与发生应力性骨折有关。年龄越大,应力性骨折的几率越高(OR 1.05[95%可信区间(CI) 1.01 ~ 1.09]);P = 0.03)。BMI越高,应力性骨折的几率越大(BMI每增加kg/m2, OR为1.09 [95% CI 1.002 ~ 1.19]; p = 0.046)。LCEA矫正幅度越大,应力性骨折的发生率越高(每一矫正程度的OR为1.05 [95% CI 1.01至1.10];p = 0.02)。与不吸食大麻的人相比,目前吸食大麻的人发生应力性骨折的几率更高(OR为3.06 [95% CI 1.2至8.0];p = 0.02),目前吸食尼古丁的人发生应力性骨折的几率也更高(OR为6.41 [95% CI 1.2至34];p = 0.03)。诊断为EDS或活动过度的患者发生应力性骨折的几率也较高(or 2.88 [95% CI 1.3 ~ 6.0]; p = 0.01)。虽然比例更高,但在双侧手术的患者中,第一次PAO和第二次PAO后应力性骨折的发生率没有差异(OR 2 [95% CI 1 ~ 4]; p = 0.07)。在控制了与应力性骨折、术前PROM评分和最近一次PAO后的时间相关的因素后,发现应力性骨折与术前和术后mHHS和iHOT-12评分的改善程度较低有关,同时也与iHOT-12达到PASS和mHHS达到MCID的几率降低有关。有应力性骨折的患者在mHHS方面的改善比无应力性骨折的患者平均少6个点(95% CI -11)。 6 ~ -0.84;P = 0.02)。应力性骨折患者iHOT-12评分的改善比无应力性骨折患者平均少12分(95% CI -20.6 ~ -2.45; p = 0.01)。应力性骨折患者达到iHOT-12 PASS的几率较低(OR 0.36 [95% CI 0.15至0.86];p = 0.02),达到mHHS MCID的几率较低(OR 0.33 [95% CI 0.13至0.83];p = 0.02)。应力性骨折与mHHS的PASS (OR 0.52 [95% CI 0.18至1.53],p = 0.24)或iHOT-12的MCID (OR 0.86 [95% CI 0.33至2.24],p = 0.76)无关。结论:年龄增加、BMI升高、LCEA矫正程度加大、大麻使用、尼古丁使用、EDS或活动过度与有症状的髋臼发育不良PAO术后应力性骨折发生风险增加相关。在至少1年的随访中,应力骨折与mHHS和iHOT-12的改善较小相关,并且达到iHOT-12的PASS和mHHS的MCID的几率较低。这些因素不是手术的障碍,而是可以指导外科医生与患者讨论,提供个性化的咨询和康复,包括关于潜在药物停用的指导,延长非负重期的使用,以及对早期功能获得的现实期望。随着更多的应力性骨折样本,可能通过多中心登记,未来的研究应旨在建立具有临床意义的相关因素阈值,并评估应力性骨折与PROMs之间的长期关系,包括骨折愈合和骨折位置的影响。证据等级:III级,治疗性研究。
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