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The Role of Dermatoscopy to Differentiate Vestibular Papillae from Condyloma Acuminate in a Pregnant Woman 皮肤镜对孕妇前庭乳头状瘤与尖锐湿疣鉴别的作用
Pub Date : 2022-03-14 DOI: 10.23937/2378-3656/1410386
Agharbi Fatima Zahra, K. A., Chiheb S.
The vestibular papillae (VP) represent an anatomical variant of the normal genital epithelium and are probably the female equivalent of pearly penile papules. It is thought that they are present in 1% of women, and this low percentage may be due to their lack of knowledge by practitioners since their diagnosis are often wrongly spotted as condyloma acuminates warts and this can lead to aggressive investigations, therapy, and anxiety in patients hence the role of dermoscopy. Here, we present a case with 39 weeks of pregnancy, who is planned to undergo cesarean section due to a wrong diagnosis of genital warts. Dermoscopy was performed to differentiate VP from condyloma and the patient gave birth vaginally without any problem. A correct diagnosis of vestibular papillomatosis prevents aggressive investigations and unnecessary therapies. Therefore, it is worthwhile to draw the attention of dermatologists to this entity.
前庭乳头(VP)是正常生殖器上皮的一种解剖变异,可能相当于女性的珍珠状阴茎丘疹。据认为,1%的女性中存在尖锐湿疣,这一低百分比可能是由于医生缺乏知识,因为他们的诊断经常被错误地发现为尖锐湿疣,这可能导致患者进行积极的调查、治疗和焦虑,因此皮肤镜检查的作用。在这里,我们提出一个病例与39周的怀孕,谁是计划接受剖宫产由于生殖器疣的错误诊断。皮肤镜检查,以区分VP尖锐湿疣和患者阴道分娩没有任何问题。前庭乳头状瘤病的正确诊断可以防止积极的调查和不必要的治疗。因此,值得引起皮肤科医生对这一实体的注意。
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引用次数: 0
Spontaneous Rupture of Renal Pelvis Secondary to Extrinsic Compression of Sigmoid Volvulus 乙状结肠扭转外源性压迫致肾盂自发性破裂
Pub Date : 2022-02-28 DOI: 10.23937/2378-3656/1410385
Sarathy Kasturi Rangan, J. Arun, Samee Abdus
Blood investigations showed a Hemoglobin of 137 g/L (Normal 110 g/L-165 g/L), raised white cell count of 17.6 × 109/L (reference 4.5 × 109/L 11 × 109/L), normal platelets and C reactive protein (CRP) of 70 mg/L (Normal < 10 mg/L). Her electrolytes, liver and renal functions were essentially normal. The eGFR at the time of presentation was 82 (reference range > 90). Urine dip stick examination was essentially within normal limits. Her chest X-ray did not identify any evidence of pneumoperitoneum while abdominal X-ray showed a classic coffee bean sign suggestive of a volvulus (Figure 1). A Computerized Tomography scan (CT scan) of Abdomen and Pelvis confirmed the features of volvulus and no other bowel related pathology was identified. No other intra-abdominal catastrophes noted on the initial CT scan. Introduction
血液检查显示血红蛋白137 g/L(正常110 g/L-165 g/L),白细胞计数升高17.6 × 109/L(参考文献4.5 × 109/L 11 × 109/L),血小板和C反应蛋白(CRP)正常70 mg/L(正常< 10 mg/L)。她的电解质、肝肾功能基本正常。患者就诊时eGFR为82(参考范围> 90)。尿浸棒检查基本在正常范围内。胸部x线未发现气腹,腹部x线显示典型的咖啡豆征,提示肠扭转(图1)。腹部和骨盆的计算机断层扫描(CT)证实肠扭转的特征,未发现其他肠道相关病理。初始CT扫描未发现其他腹腔内病变。介绍
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引用次数: 0
Blue Laser Imaging and Magnification Endoscopy as a Tool for the Detection of Helicobacter pylori Infected Mucosa 蓝色激光成像和放大内窥镜作为检测幽门螺杆菌感染粘膜的工具
Pub Date : 2022-02-28 DOI: 10.23937/2378-3656/1410384
Leal-Quiroga Ulises, Kane Abigail Sara, Mendoza-Fuerte Eduardo, Borjas-Almaguer Omar David, Leal Eugenia, Castañeda-Sepúlveda Rafael
Background: There are multiple diagnostic methods for the detection of H. pylori; however, because most are not cost-effective and have low sensibility and specificity, gastric biopsy remains the gold standard for diagnosis. H. pylori’s patchy distribution in the gastric mucosa requires multiple biopsy samples to accurately diagnose infection. This study’s objective is to identify the diagnostic value of using BLI-Bright with magnification endoscopy as a tool for guided biopsy sampling in patients with suspected H. pylori infection. Methods: This study was conducted by retrospective analysis of 200 case files of patients who underwent upper endoscopy at Christus Muguerza Hospital Sur in Monterrey, Mexico between August 2016 and June 2018. One hundred ninety-three patient files met the selection criteria. To establish the diagnostic significance of occupied/ unoccupied gastric pits, sensibility, specificity, and positive and negative predictive values were calculated based on histological findings. Results: Predicting H. pylori infection in occupied/ unoccupied pits has a sensitivity of 66.00%, specificity of 95.10%, a positive predictive value of 85.50%, and a negative predictive value of 88.89%. Analysis of gastric pits using BLI-Bright with magnification endoscopy is more sensitive and specific than rapid urease testing for the diagnosis of H. pylori. Conclusions: Given its relatively high negative predictive value, finding empty gastric pits suggests a low probability of finding H. pylori. Blue Laser Imaging (BLI)-Bright with magnification endoscopy is not a replacement for histologic examination, but rather a tool to help select potentially infected areas of the stomach based on the appearance of gastric pits.
背景:幽门螺杆菌的诊断方法多种多样;然而,由于大多数方法成本不高,敏感性和特异性低,因此胃活检仍然是诊断的金标准。幽门螺杆菌在胃粘膜的斑片状分布需要多次活检才能准确诊断感染。本研究的目的是确定在疑似幽门螺杆菌感染的患者中,使用BLI-Bright和放大内窥镜作为引导活检取样的工具的诊断价值。方法:回顾性分析2016年8月至2018年6月在墨西哥蒙特雷Christus Muguerza医院接受上内镜检查的200例患者的病例档案。193份患者档案符合入选标准。为了确定胃窝占位/未占位的诊断意义,根据组织学结果计算敏感性、特异性、阳性预测值和阴性预测值。结果:预测占用坑/未占用坑幽门螺杆菌感染的敏感性为66.00%,特异性为95.10%,阳性预测值为85.50%,阴性预测值为88.89%。BLI-Bright联合放大内镜检查胃凹比快速脲酶检测诊断幽门螺杆菌更敏感、更特异。结论:胃空窝阴性预测值较高,提示发现幽门螺杆菌的概率较低。蓝色激光成像(BLI)-明亮的放大内窥镜检查不是组织学检查的替代品,而是一种根据胃凹的外观帮助选择胃潜在感染区域的工具。
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引用次数: 0
Patients with Pelvic Inflammatory Disease vs. Tuboovarian Abscess: Comparison of Follow-Up and Treatment Processes 盆腔炎与输卵管腔脓肿患者:随访和治疗过程的比较
Pub Date : 2022-02-28 DOI: 10.23937/2378-3656/1410383
K. Busra
Background: Pelvic inflammatory disease (PID) is an infection of the upper vaginal tract in women that can be subclinical or severe, affecting any or all of the uterus, fallopian tubes, and ovaries. Tuboovarian abscess (TOA) is a common consequence of PID. The purpose of this study is to compare the demographic features, symptoms, clinical findings, and treatment techniques of patients hospitalized with the diagnosis of PID and TOA, to assess their response to treatment protocols and therapy, and to evaluate the development of recurrence. Methods: The study, a descriptive retrospective cohort analysis, included 318 patients with PID and TOA who were admitted to the Gynecology Clinic of the University of Health Sciences Etlik Zubeyde Hanim Women’s Health Training and Research Hospital between January 1, 2016 and August 1, 2019. Results: In terms of age, gravida, parity, BMI, educational background, profession, comorbidities, and previous PID attacks, there were no statistically significant differences between the PID and TOA groups. Among birth control techniques, the TOA group had a higher rate of intrauterine device usage, infection indicators (white blood cell, C-reactive protein, and erythrocyte sedimentation rate), and smoking. The PID group had a significantly greater prior history of uterus surgery. While the patients’ symptoms and length of complaints were comparable in both groups, the duration of antibiotherapy was statistically longer in the TOA group. Conclusion: The incidence of active smoking and the mean hospitalization day were found to be considerably higher in the TOA group, which was consistent with the literature in our series. In the literature, the most risky period for the development of PID was stated to be 21 days after the insertion of an intrauterine device, whereas in our study, it was determined that 20.8 percent of the acute PID group and 47.7 percent of the TOA group had an intrauterine device, and that these patients had long-term use of intrauterine devices. Although there is evidence that laparoscopic surgery may be performed successfully in TOA surgery, most surgeons prefer laparotomy. In our series, the rate of minimally invasive surgery was 88 percent. The study’s strength is that it is the biggest single-center cohort investigation of hospitalized PID and TOA patients, comparing demographic and physical features, symptoms and signs, clinical course, treatment procedures, and followup methods. There have been few studies in this area, and the number of cases is fewer than in our series. Our study’s limitations include the fact that it is retrospective, and not all diagnoses can be validated by culture.
背景:盆腔炎(PID)是一种发生在女性阴道上段的感染,可表现为亚临床或严重,影响子宫、输卵管和卵巢的任何或全部。输卵管脓肿(TOA)是PID的常见后果。本研究的目的是比较诊断为PID和TOA的住院患者的人口学特征、症状、临床表现和治疗技术,评估他们对治疗方案和治疗的反应,并评估复发的发展。方法:本研究采用描述性回顾性队列分析,纳入2016年1月1日至2019年8月1日在卫生科学大学Etlik Zubeyde Hanim妇女健康培训研究医院妇科门诊就诊的318例PID和TOA患者。结果:在年龄、妊娠、胎次、BMI、学历、职业、合并症、既往PID发作等方面,PID组与TOA组比较差异无统计学意义。在节育技术中,TOA组的宫内节育器使用率、感染指标(白细胞、c反应蛋白和红细胞沉降率)和吸烟率较高。PID组有更大的既往子宫手术史。虽然两组患者的症状和主诉时间相当,但TOA组抗生素治疗的持续时间在统计学上更长。结论:TOA组的主动吸烟发生率和平均住院天数明显高于TOA组,这与本系列文献一致。在文献中,PID发展的最危险时期被认为是宫内节育器插入后21天,而在我们的研究中,确定20.8%的急性PID组和47.7%的TOA组有宫内节育器,并且这些患者长期使用宫内节育器。虽然有证据表明腹腔镜手术可以成功地进行TOA手术,但大多数外科医生更倾向于剖腹手术。在我们的研究中,微创手术的比例是88%。该研究的优势在于,它是对住院PID和TOA患者进行的最大的单中心队列调查,比较了人口学和体格特征、症状和体征、临床病程、治疗程序和随访方法。这方面的研究很少,病例数也少于本系列。我们研究的局限性包括它是回顾性的,并不是所有的诊断都可以通过培养来验证。
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引用次数: 0
Integrated Management Strategies (Diagnosis, Treatment, and Wound Care Management) for Improved Clinical Outcomes of Buruli Ulcer in Ghana: A Retrospective Case Report in the Ga West Municipal Hospital, Amasaman 综合管理策略(诊断、治疗和伤口护理管理)改善加纳布鲁里溃疡临床结果:阿马萨曼加西市立医院回顾性病例报告
Pub Date : 2022-01-31 DOI: 10.23937/2378-3656/1410379
Akolgo Gideon Atinga, A. Anthony, Pereko Janet, Tuffour Joseph, Kotey Nana Konama, Paintsil Albert, Adwapa Gladys, Croffie Akosua Agyapomaa, Donkoh Samuel Kwarteng, Amewu Richard
Buruli ulcer is a necrotizing skin infection caused by Mycobacterium ulcerans. BU lesions may start with characteristic painlessness but most often, the typical presentations of the disease are characterized by large ulcers with undermined edges. If left untreated, BU lesions may result in extensive ulceration that can cover 15% of the body. Even though public sensitization and education have resulted in sufficient and improved knowledge about the etiology of the disease in Ghana, patients still report to health facilities with advanced forms of the disease. As a result, the management of Buruli ulcer (BU) is increasingly becoming a challenge. Therefore, this case report highlights an integrated approach comprising of clinical diagnosis, laboratory confirmation, antibiotic treatment, and wound management of four confirmed cases of Buruli ulcer diseases that were managed at the BU Ward of the Ga West Municipal Hospital. Surgical interventions including debridement and skin grafting coupled with comprehensive wound care and/or physiotherapy were also employed in instances where antibiotic therapy alone was not sufficient for complete healing. The application of integrated management led to full recovery of all the patients, albeit with different times to healing depending on the severity of the lesions.
布鲁里溃疡是一种由溃疡分枝杆菌引起的坏死性皮肤感染。布鲁里溃疡病变可能以特征性无痛开始,但最常见的是,该疾病的典型表现为边缘受损的大溃疡。如果不及时治疗,布鲁里溃疡病变可能导致广泛的溃疡,可覆盖身体的15%。尽管在加纳,公众宣传和教育使人们对该病的病因有了充分和改进的认识,但患者仍向卫生机构报告患有这种疾病的晚期形式。因此,布鲁里溃疡(BU)的管理日益成为一项挑战。因此,本病例报告强调了一种综合方法,包括临床诊断、实验室确认、抗生素治疗和在加西市立医院布鲁里溃疡病房治疗的4例布鲁里溃疡确诊病例的伤口管理。在抗生素治疗不足以完全愈合的情况下,也采用手术干预措施,包括清创和植皮,结合全面的伤口护理和/或物理治疗。综合治疗的应用使所有患者完全康复,尽管根据病变的严重程度有不同的愈合时间。
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引用次数: 0
Regression of Diabetic Macular Edema by Remission of Type 2 Diabetes with Plant-Based Diet: A Case Report and Review 植物性饮食缓解2型糖尿病后糖尿病黄斑水肿的消退:一个病例报告和回顾
Pub Date : 2022-01-31 DOI: 10.23937/2378-3656/1410381
Panigrahi Gunadhar
The current practice in the management DR has been primarily aimed at its neovascular complications, and rests upon the use of laser photocoagulation, intravitreal anti-VGEF injections, and on occasion glucocorticoid therapy. However, these treatments are not curative and there is increasing evidence that anti-VEGF treatment is unlikely to improve retinal perfusion and may not prevent gradual progression of nonperfusion or loss of peripheral visual field associated with worsening diabetes-related eye disease [7]. Moreover, there are many short term and long-term complications associated with these treatments. Diabetic retinopathy is the result of the convergence of many metabolic abnormalities leading to retinal vasculature dysfunction, inflammation, and neurodegeneration [8]. DR has been considered a microcirculatory disease of the retina. However, there is emerging evidence to suggest that retinal neurodegeneration is an early event in the pathogenesis of DR [9]. Introduction
目前治疗DR的实践主要针对其新生血管并发症,并依赖于激光光凝、玻璃体内抗vgef注射和偶尔的糖皮质激素治疗。然而,这些治疗方法并不能治愈,而且越来越多的证据表明抗vegf治疗不太可能改善视网膜灌注,也可能无法预防与糖尿病相关眼病[7]恶化相关的非灌注性逐渐进展或周围视野丧失。此外,与这些治疗相关的许多短期和长期并发症。糖尿病视网膜病变是多种代谢异常聚集的结果,导致视网膜血管功能障碍、炎症和神经变性[8]。DR被认为是一种视网膜微循环疾病。然而,越来越多的证据表明视网膜神经变性是DR[9]发病机制的早期事件。介绍
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引用次数: 2
Trendelenburg Gait Improved by Trigger Point and Scar Tissue Lidocaine Injections: A Case Report 触发点和疤痕组织注射利多卡因改善Trendelenburg步态1例报告
Pub Date : 2022-01-31 DOI: 10.23937/2378-3656/1410382
K. Alexander, W. Rosie, Patel Rachel, LaFontaine Joseph
This case report describes a 74-year-old Caucasian female patient who presented with bilateral gluteus muscle trigger point pain, decreased gluteus medius strength, a substantial transverse abdominal scar, and a history of knee replacement culminating in a Trendelenburg gait and chronic pain. Treatment of the patients’ symptoms with lidocaine solution injections, known as neural therapy, into the bilateral gluteus muscle trigger points and along scar tissue facial planes yielded markedly improved gait and immediate resolution of trigger point pain. Neural therapy used in this patient, involves the injection of anesthetic solution into trigger points and scar tissue, to release muscle tension and encourage resetting of dysfunctional nerve pathways.
本病例报告描述了一名74岁的白人女性患者,其表现为双侧臀肌触发点疼痛,臀中肌力量下降,腹部有大量横向疤痕,膝关节置换术史,最终表现为Trendelenburg步态和慢性疼痛。将利多卡因溶液注射到双侧臀肌触发点和沿疤痕组织面平面治疗患者症状,可显著改善步态并立即缓解触发点疼痛。该患者使用的神经疗法包括将麻醉溶液注射到触发点和疤痕组织,以释放肌肉紧张并促进功能失调神经通路的重置。
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引用次数: 0
Huge Peri Renal Extra Adrenal Myelolipoma 巨大肾周肾上腺外骨髓瘤
Pub Date : 2022-01-31 DOI: 10.23937/2378-3656/1410380
S. M, Fatma A. Ben, Lahouel Y, Kerkeni C, Jerbi S
Extra-adrenal myelolipomas are a group of mesenchymal tumors which consist of a mixture of mature adipose tissue with hematopoietic cells. This intriguing tumor most commonly occurs within the adrenal gland; however, it has been occasionally found within the pelvis, thorax, retroperitoneal space, and various other sites throughout the body [1,2]. The physiopathology is not yet clearly explained, Amin, et al. [3] suggest that there may be a relationship between the re-activation of primitive peritoneal foci of extramedullary hematopoiesis under pathological stresses (severe anemia, sepsis, myeloproliferative disease ...) and the origin and progression of extraadrenal myelolipomas.
肾上腺外骨髓脂肪瘤是一组由成熟脂肪组织和造血细胞混合组成的间充质肿瘤。这种有趣的肿瘤最常见于肾上腺;然而,偶尔也会在骨盆、胸腔、腹膜后间隙和全身其他部位发现[1,2]。生理病理尚不清楚,Amin等[3]认为病理应激(严重贫血、脓毒症、骨髓增生性疾病等)下髓外造血原始腹膜灶的再激活可能与肾上腺外骨髓脂肪瘤的发生和发展有关。
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引用次数: 0
An Unusual Complication of Mesenteric-Portal Axis Thrombosis and Septic Shock in a Patient with Mesangial Proliferative Glomerulonephritis 系膜增殖性肾小球肾炎患者肠系膜-门脉轴血栓形成及感染性休克的罕见并发症
Pub Date : 2021-12-31 DOI: 10.23937/2378-3656/1410375
Luxmi Sicharam Vijaya, Yue Sun, Qing Chen Xing, Fang Cao Fang, Fedally Swalay, Gang Du Xiao
Thromboembolic events contribute to the most serious outcomes in patients with nephrotic syndrome. We report a case of a young male patient with mesangial proliferative glomerulonephritis presenting with nephrotic syndrome, which rapidly progressed to mesenteric and portal veins thrombosis and septic shock, ultimately leading to death.
血栓栓塞事件是肾病综合征患者最严重的后果。我们报告一例年轻男性患者系膜增生性肾小球肾炎表现为肾病综合征,并迅速发展为肠系膜和门静脉血栓形成和感染性休克,最终导致死亡。
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引用次数: 0
Acute Limb Ischemia as an Unusual Presentation of Spontaneous Coronary Artery Dissection 急性肢体缺血是自发性冠状动脉夹层的一种不寻常表现
Pub Date : 2021-12-31 DOI: 10.23937/2378-3656/1410377
Musmar Basel, Gabi Alaa
Spontaneous coronary artery dissection (SCAD) is a rare, though, important cause of acute coronary syndrome that is more commonly seen in young and middle-aged women without risk factors for, or a history of, coronary artery disease. Acute embolization of left ventricular (LV) thrombus is an uncommon but known cause of acute limb ischemia. In this case, we present a rare case of SCAD that led to acute limb ischemia due to embolization of LV thrombus. SCAD is a very rare cause of LV thrombus, but still should be taken in consideration. In this case, we present a rare case of SCAD that led to acute limb ischemia.
自发性冠状动脉剥离(SCAD)是一种罕见的急性冠状动脉综合征的重要原因,在没有冠状动脉疾病危险因素或病史的年轻和中年妇女中更为常见。左心室血栓的急性栓塞是一种罕见但已知的急性肢体缺血的原因。在这个病例中,我们报告了一个罕见的SCAD病例,由于左室血栓栓塞导致急性肢体缺血。SCAD是一个非常罕见的左室血栓的原因,但仍应考虑。在这个病例中,我们提出了一个罕见的SCAD导致急性肢体缺血的病例。
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引用次数: 0
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Clinical Medical Reviews and Case Reports
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