Clinical Oral Implants Research最新文献_第5页

Validation of a novel AI-based automated multimodal image registration of CBCT and intraoral scan aiding presurgical implant planning 验证基于人工智能的新型 CBCT 和口腔内扫描自动多模态图像配准技术，帮助进行术前种植规划。

IF 4.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Implants Research

Pub Date : 2024-08-05 DOI: 10.1111/clr.14338

Bahaaeldeen M. Elgarba, Rocharles Cavalcante Fontenele, Saleem Ali, Abdullah Swaity, Jan Meeus, Sohaib Shujaat, Reinhilde Jacobs

Objectives

The objective of this study is to assess accuracy, time-efficiency and consistency of a novel artificial intelligence (AI)-driven automated tool for cone-beam computed tomography (CBCT) and intraoral scan (IOS) registration compared with manual and semi-automated approaches.

Materials and Methods

A dataset of 31 intraoral scans (IOSs) and CBCT scans was used to validate automated IOS-CBCT registration (AR) when compared with manual (MR) and semi-automated registration (SR). CBCT scans were conducted by placing cotton rolls between the cheeks and teeth to facilitate gingival delineation. The time taken to perform multimodal registration was recorded in seconds. A qualitative analysis was carried out to assess the correspondence between hard and soft tissue anatomy on IOS and CBCT. In addition, a quantitative analysis was conducted by measuring median surface deviation (MSD) and root mean square (RMS) differences between registered IOSs.

Results

AR was the most time-efficient, taking 51.4 ± 17.2 s, compared with MR (840 ± 168.9 s) and SR approaches (274.7 ± 100.7 s). Both AR and SR resulted in significantly higher qualitative scores, favoring perfect IOS-CBCT registration, compared with MR (p = .001). Additionally, AR demonstrated significantly superior quantitative performance compared with SR, as indicated by low MSD (0.04 ± 0.07 mm) and RMS (0.19 ± 0.31 mm). In contrast, MR exhibited a significantly higher discrepancy compared with both AR (MSD = 0.13 ± 0.20 mm; RMS = 0.32 ± 0.14 mm) and SR (MSD = 0.11 ± 0.15 mm; RMS = 0.40 ± 0.30 mm).

Conclusions

The novel AI-driven method provided an accurate, time-efficient, and consistent multimodal IOS-CBCT registration, encompassing both soft and hard tissues. This approach stands as a valuable alternative to manual and semi-automated registration approaches in the presurgical implant planning workflow.

研究目的本研究旨在评估一种新型人工智能（AI）驱动的锥形束计算机断层扫描（CBCT）和口腔内扫描（IOS）自动配准工具与手动和半自动方法相比的准确性、时间效率和一致性：31个口内扫描（IOS）和CBCT扫描数据集用于验证IOS-CBCT自动配准（AR）与手动（MR）和半自动配准（SR）的比较。进行 CBCT 扫描时，在脸颊和牙齿之间放置棉卷，以方便划定牙龈。以秒为单位记录进行多模态配准所需的时间。我们进行了定性分析，以评估 IOS 和 CBCT 上硬组织和软组织解剖之间的对应关系。此外，还通过测量已登记 IOS 之间的中位表面偏差（MSD）和均方根差（RMS）进行了定量分析：结果：与 MR（840 ± 168.9 秒）和 SR（274.7 ± 100.7 秒）相比，AR 最省时，只需 51.4 ± 17.2 秒。与 MR 相比，AR 和 SR 的定性评分明显更高，更倾向于完美的 IOS-CBCT 配准（p = .001）。此外，AR 的定量性能明显优于 SR，表现为 MSD（0.04 ± 0.07 mm）和 RMS（0.19 ± 0.31 mm）较低。相比之下，MR 与 AR（MSD = 0.13 ± 0.20 mm；RMS = 0.32 ± 0.14 mm）和 SR（MSD = 0.11 ± 0.15 mm；RMS = 0.40 ± 0.30 mm）相比，差异明显更大：新颖的人工智能驱动方法提供了准确、省时和一致的多模态 IOS-CBCT 注册，包括软组织和硬组织。在术前种植规划工作流程中，这种方法是手动和半自动化配准方法的重要替代方案。

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引用次数: 0

Randomized controlled trial on the efficacy of a custom-made, fully guided implant system for flapless crestal sinus floor elevation: Accuracy and patient-reported outcomes. 无瓣嵴窦底提升术的定制全引导种植系统疗效随机对照试验：准确性和患者报告结果。

IF 4.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Implants Research

Pub Date : 2024-08-05 DOI: 10.1111/clr.14341

Jongseung Kim, Jin-Young Park, Joo-Yeon Lee, Da-Mi Kim, Jungwon Lee, Ui-Won Jung, Young-Jun Lim, Jae-Kook Cha

Objective: To compare fully guided flapless implant surgery using a light-cured surgical guide (FG group) with partially guided open flap surgery (PG group) in the posterior maxilla when performing simultaneous sinus floor elevation in terms of the accuracy, time requirements, and patient/clinician-reported outcomes (PROMs and CROMs).

Materials and methods: In this study, 56 tissue-level implants were placed with crestal sinus floor elevation in 56 patients at single-tooth sites, with 28 implants allocated to the PG group and 28 to the FG group. The deviations of the placed implants from the virtually planned positions were measured at the implant platform and apex and for the angular deviation. The presurgical preparation time and the duration of surgery were measured. PROMs and CROMs were made by administering questionnaires at multiple time points.

Results: Horizontal deviations at the platform and apex and the angular deviation were significantly smaller in the FG group than the PG group (p < .05). Presurgical preparation and surgery times were significantly shorter in the FG group (p < .001). Patient satisfaction and willingness to receive repeat treatment were significantly better in the FG group than in the PG group (p < .005 and .025, respectively). Clinicians were more satisfied in the FG group than the PG group (p < .05).

Conclusion: When placing an implant with sinus floor elevation, the flapless approach using a fully guided surgical system can be more accurate, faster, and increase the satisfaction of both the clinician and patient compared to the partially guided surgery.

目的比较使用光固化手术导板的全引导无瓣种植手术（FG组）与部分引导开放瓣手术（PG组）在上颌后牙同时进行上颌窦底提升时的准确性、所需时间以及患者/医师报告结果（PROMs和CROMs）：在这项研究中，56 位患者在单牙部位植入了 56 颗组织水平种植体，同时进行了嵴窦底提升，其中 28 颗种植体被分配到 PG 组，28 颗被分配到 FG 组。在种植体平台和顶点测量了植入种植体与虚拟计划位置的偏差以及角度偏差。对术前准备时间和手术持续时间进行了测量。通过在多个时间点进行问卷调查，得出了PROM和CROM：结果：FG 组的平台和顶点水平偏差以及角度偏差明显小于 PG 组（p 结论：FG 组的角度偏差明显小于 PG 组：在植入上颌窦底抬高种植体时，与部分引导手术相比，使用完全引导手术系统的无瓣方法更准确、更快速，并能提高临床医生和患者的满意度。

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引用次数: 0

Fracture rate and risk factors associated with the fracture of narrow diameter implants: A long-term retrospective analysis 与窄直径植入物骨折相关的骨折率和风险因素：长期回顾性分析

IF 4.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Implants Research

Pub Date : 2024-08-03 DOI: 10.1111/clr.14334

Romulo M. Lustosa, João Garcez-Filho, Marcos Seabra, Ricardo Puziol de Oliveira, Flávia Matarazzo, Maurício G. Araújo

Objectives

The objective of this long-term retrospective study was to evaluate the fracture rate and the risk factors associated with the fracture of 3.3 mm narrow diameter implants (NDIs).

Materials and Methods

A total of 524 records of patients rehabilitated with 3.3 mm NDIs between 1997 and 2015 were assessed. Data on patients, implants, and prostheses were collected, and descriptive analysis of the variables was performed. NDIs were separated into 2 groups: “fractured” and “non-fractured”, and a multilevel logistic regression model was applied to identify the risk factors associated with NDI fracture.

Results

Eighty-four patients were removed from the analysis for interrupting follow-up or presenting failures other than fractures. Of the 440 patients included (64.66 ± 13.4 years), 272 were females (61.8%), and 168 males (38.2%), and mean follow-up time was 129 ± 47.1 months. Of the 1428 NDIs, 15 (1.05%) in 9 patients (2.04%) fractured during the studied period. Ten fractures (66.66%) happened in 6 patients (66.66%) showing signs of parafunction. NDI with modified sandblasted, large grit, acid-etched surface was the only implant variable to show a protective statistical significance (p = .0439).

Conclusions

NDI fracture was a rare event in the studied sample. NDIs manufactured with modified sandblasted, large grit, acid-etched surface may provide extra protection against NDI fracture. Patient-specific factors and implant characteristics should be carefully considered to limit the risk of fracture of 3.3 mm NDIs.

研究目的这项长期回顾性研究的目的是评估 3.3 毫米窄直径种植体（NDI）的骨折率以及与之相关的风险因素：评估了1997年至2015年间使用3.3毫米窄直径种植体进行康复治疗的524名患者的记录。收集了患者、种植体和修复体的数据，并对变量进行了描述性分析。NDI 被分为两组："应用多层次逻辑回归模型确定与NDI骨折相关的风险因素：84名患者因中断随访或出现骨折以外的其他故障而从分析中剔除。在纳入的 440 名患者（64.66 ± 13.4 岁）中，女性 272 名（61.8%），男性 168 名（38.2%），平均随访时间为 129 ± 47.1 个月。在 1428 例 NDI 中，有 9 名患者（2.04%）的 15 例（1.05%）在研究期间发生骨折。有 6 名患者（66.66%）的 10 处骨折（66.66%）显示出功能障碍的迹象。改良喷砂、大颗粒、酸蚀表面的 NDI 是唯一显示出保护性统计学意义（p = .0439）的种植体变量：结论：在所研究的样本中，NDI断裂的情况很少发生。采用改良喷砂、大颗粒、酸蚀表面制造的 NDI 可为防止 NDI 骨折提供额外保护。应仔细考虑患者的特定因素和植入物的特性，以限制 3.3 毫米 NDI 骨折的风险。

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引用次数: 0

The systemic impact of non-surgical treatment of peri-implantitis with or without adjunctive systemic metronidazole: Secondary analysis of a randomized clinical trial. 使用或不使用甲硝唑辅助系统性治疗种植体周围炎的非手术疗法对全身的影响：随机临床试验的二次分析。

IF 4.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Implants Research

Pub Date : 2024-08-02 DOI: 10.1111/clr.14339

Antonio Liñares, Jose Dopico, Carlota Blanco, Alex Pico, Tomás Sobrino, Juan Blanco, Yago Leira

Objectives: The aim of this study was to evaluate the systemic effect of non-surgical peri-implantitis treatment (NSPIT) with or without the administration of systemic metronidazole.

Methods: In this secondary analysis from a previously published clinical trial (NCT03564301), peri-implantitis patients were randomized into two groups: test, receiving NSPIT plus 500 mg of oral systemic metronidazole three times a day for 7 days (n = 10); and control group, receiving NSPIT plus placebo (n = 11). Serum samples were obtained at baseline, 3 and 6 months after therapy to determine levels of inflammatory biomarkers, lipid fractions and complete blood counts.

Results: Both treatment modalities produced improvements in clinical and radiographic parameters. After 6 months from NSPIT, a substantial reduction in C-reactive protein (6.9 mg/dL; 95% CI: 3.7 to 9.9, p < .001) and low-density lipoprotein cholesterol (21.8 mg/dL; 95% CI: -6.9 to 50.5, p = .013) as well as a modest increase in neutrophils counts (0.4 × 10³/μL; 95% CI: -0.4 to 1.1, p = .010) was observed in the control group while the test group showed a significant reduction of TNF-α (110.1; 95% CI: 38.9 to 181.4, p = .004).

Conclusions: NSPIT showed a short-term beneficial systemic effect regardless of adjunctive use of systemic metronidazole.

研究目的本研究旨在评估非手术种植体周围炎治疗（NSPIT）加或不加甲硝唑的全身效果：在这项对之前发表的临床试验（NCT03564301）进行的二次分析中，种植体周围炎患者被随机分为两组：试验组，接受NSPIT加500毫克口服甲硝唑治疗，每天三次，连续7天（n=10）；对照组，接受NSPIT加安慰剂治疗（n=11）。在基线、治疗后 3 个月和 6 个月采集血清样本，以确定炎症生物标志物、脂质组分和全血细胞计数的水平：结果：两种治疗方法都改善了临床和影像学参数。NSPIT 治疗 6 个月后，对照组的 C 反应蛋白大幅降低（6.9 mg/dL；95% CI：3.7 至 9.9，p 3/μL；95% CI：-0.4 至 1.1，p = .010），而试验组的 TNF-α 显著降低（110.1；95% CI：38.9 至 181.4，p = .004）：结论：无论是否辅助使用甲硝唑，NSPIT都能产生短期有益的全身效应。

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引用次数: 0

Alveolar ridge bone changes in patients treated with the split-crest technique with simultaneous implant placement: A retrospective longitudinal observational study 采用分瓣牙冠技术同时植入种植体治疗患者牙槽嵴骨的变化：一项回顾性纵向观察研究。

IF 4.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Implants Research

Pub Date : 2024-07-30 DOI: 10.1111/clr.14331

João Garcez-Filho, Débora de Almeida Bianco, André Barbisan de Souza, Ricardo Puziol de Oliveira, Flávia Matarazzo, Maurício G. Araújo

Objectives

To investigate long-term alveolar ridge bone changes in patients treated with the split-crest technique (SCT) with simultaneous implant placement.

Materials and Methods

Alveolar ridge width (ARW) was measured with a caliper immediately before (ARW1) and after SCT (ARW2) with a caliper. Existing CBCT scans taken at least 5 years postoperatively were used to assess the healed ARW (ARWF), buccal bone thickness (BBT), and lingual/palatal bone thickness (L/PBT) at 0, 3, and 5 mm apically from implant platform level (IPL). The distance between IPL and buccal bone crest (IPL-BBC) was also measured. Findings were compared with Wilcoxon and Student's t tests (p < .05).

Results

Records of thirty patients with 85 implants were included. Eleven patients (31 implants) presented CBCT scans taken in two separate occasions, resulting in 116 measurements. Tomographic follow-up ranged from 5 to 18 years (11.5 ± 4.18 years). Mean ARW increased from 3.2 ± 0.6 to 6.6 ± 0.48 mm after SCT, but significantly reduced overtime to 4.46 ± 0.83 mm (ARWF) (p < .0001). Mean BBT was 0.5 ± 0.9, 1.3 ± 0.9, and 2.0 ± 1.2 mm, while mean L/PBT was 0.9 ± 0.7, 1.6 ± 0.9, and 2.1 ± 1.0 mm at 0, 3, and 5 mm from IPL, respectively. IPL-BBC distance varied up to 8.7 mm (1.4 ± 2.0 mm), with 56/116 measurements (51/85 implants) showing IPL-BBC = 0 mm.

Conclusion

Although SCT with simultaneous implant placement can predictably increase ARW postoperatively, ARW tended to significantly reduce over time, due to reductions in BBT and L/PBT, especially coronally. Nonetheless, 60% of the implants still presented some buccal bone at IPL.

目的研究采用分离式牙槽嵴技术（SCT）同时植入种植体治疗的患者牙槽嵴骨质的长期变化：用卡尺测量牙槽嵴宽度（ARW），测量前为 ARW1，测量后为 ARW2。使用术后至少 5 年的 CBCT 扫描来评估从种植体平台水平（IPL）向下 0、3 和 5 mm 处愈合的 ARW（ARWF）、颊骨厚度（BBT）和舌腭骨厚度（L/PBT）。此外，还测量了 IPL 与颊骨嵴之间的距离（IPL-BBC）。结果通过 Wilcoxon 检验和学生 t 检验进行比较（p 结果：共纳入了 30 位患者的 85 个种植体的记录。有 11 名患者（31 个种植体）在两个不同的场合进行了 CBCT 扫描，共进行了 116 次测量。断层扫描随访时间从 5 年到 18 年不等（11.5 ± 4.18 年）。SCT 后，平均 ARW 从 3.2 ± 0.6 mm 增加到 6.6 ± 0.48 mm，但随着时间的推移显著降低到 4.46 ± 0.83 mm（ARWF）（p 结论：虽然 SCT 与种植体同时植入，但种植体的平均 ARW 从 3.2 ± 0.6 mm 增加到 6.6 ± 0.48 mm：虽然同时植入种植体的 SCT 可预测术后 ARW 会增加，但随着时间的推移，ARW 有明显减少的趋势，原因是 BBT 和 L/PBT 的减少，尤其是冠状面。尽管如此，60% 的种植体在 IPL 时仍有一些颊骨。

{"title":"Alveolar ridge bone changes in patients treated with the split-crest technique with simultaneous implant placement: A retrospective longitudinal observational study","authors":"João Garcez-Filho, Débora de Almeida Bianco, André Barbisan de Souza, Ricardo Puziol de Oliveira, Flávia Matarazzo, Maurício G. Araújo","doi":"10.1111/clr.14331","DOIUrl":"10.1111/clr.14331","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To investigate long-term alveolar ridge bone changes in patients treated with the split-crest technique (SCT) with simultaneous implant placement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Alveolar ridge width (ARW) was measured with a caliper immediately before (ARW1) and after SCT (ARW2) with a caliper. Existing CBCT scans taken at least 5 years postoperatively were used to assess the healed ARW (ARWF), buccal bone thickness (BBT), and lingual/palatal bone thickness (L/PBT) at 0, 3, and 5 mm apically from implant platform level (IPL). The distance between IPL and buccal bone crest (IPL-BBC) was also measured. Findings were compared with Wilcoxon and Student's <i>t</i> tests (<i>p</i> < .05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Records of thirty patients with 85 implants were included. Eleven patients (31 implants) presented CBCT scans taken in two separate occasions, resulting in 116 measurements. Tomographic follow-up ranged from 5 to 18 years (11.5 ± 4.18 years). Mean ARW increased from 3.2 ± 0.6 to 6.6 ± 0.48 mm after SCT, but significantly reduced overtime to 4.46 ± 0.83 mm (ARWF) (<i>p</i> < .0001). Mean BBT was 0.5 ± 0.9, 1.3 ± 0.9, and 2.0 ± 1.2 mm, while mean L/PBT was 0.9 ± 0.7, 1.6 ± 0.9, and 2.1 ± 1.0 mm at 0, 3, and 5 mm from IPL, respectively. IPL-BBC distance varied up to 8.7 mm (1.4 ± 2.0 mm), with 56/116 measurements (51/85 implants) showing IPL-BBC = 0 mm.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Although SCT with simultaneous implant placement can predictably increase ARW postoperatively, ARW tended to significantly reduce over time, due to reductions in BBT and L/PBT, especially coronally. Nonetheless, 60% of the implants still presented some buccal bone at IPL.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"35 11","pages":"1440-1451"},"PeriodicalIF":4.8,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Do the number of zirconia implants and the thickness of CBCT image reconstruction affect the detection of peri-implant bone defect? A diagnostic accuracy ex vivo study 氧化锆种植体的数量和 CBCT 图像重建的厚度会影响种植体周围骨缺损的检测吗？活体诊断准确性研究

IF 4.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Implants Research

Pub Date : 2024-07-27 DOI: 10.1111/clr.14336

Juliana Batista Melo da Fonte, Rocharles Cavalcante Fontenele, Amanda Farias-Gomes, Débora Costa Ruiz, Maria Fernanda Silva Andrade-Bortoletto, Saulo L. Sousa Melo, Deborah Queiroz Freitas

Objectives

To evaluate the influence of multiplanar reconstruction thickness on the detection of peri-implant bone defects with a standalone zirconia implant and compare it to when another implant is in the vicinity using cone-beam computed tomography (CBCT).

Materials and Methods

Five dry human mandibles were used to create twenty implant sites in the second premolar and first molar regions. The OP300 Maxio was used to acquire CBCT images (90 kVp, 6.3 mA, 5 × 5 cm FOV, and 0.125 mm³ voxel size) before and after creating 3 mm peri-implant bone defects in the buccal aspect of the premolar region. Half of the scans featured a single zirconia implant in the premolar region, while the others had two implants in the premolar and molar regions. Three reconstruction thicknesses (0.125 mm, 1 mm, and 2 mm) were considered for the multiplanar reconstruction analyses. Five oral and maxillofacial radiologists assessed the detection of peri-implant bone defects using a 5-point scale. Diagnostic parameters were calculated and compared using Two-way ANOVA (α = .05).

Results

The studied factors showed no significant influence on the diagnosis of peri-implant bone defects (p > .05). Diagnostic performance was notably higher with a single implant, especially with a 2-mm reconstruction thickness (AUC = 0.88, sensitivity = 0.68, specificity = 0.94). Although the differences were not statistically significant, the results were more modest when two implants were present (AUC = 0.80, sensitivity = 0.58, specificity = 0.82).

Conclusions

The presence of an adjacent zirconia implant and variations in reconstruction thickness did not influence the detection of 3 mm buccal peri-implant bone defects on CBCT images.

目的评估多平面重建厚度对使用独立氧化锆种植体检测种植体周围骨缺损的影响，并使用锥束计算机断层扫描 (CBCT) 与附近有其他种植体时进行比较。在前磨牙区域的颊侧创建 3 mm 的种植体周围骨缺损前后，使用 OP300 Maxio 采集 CBCT 图像（90 kVp、6.3 mA、5 × 5 cm FOV 和 0.125 mm3 象素大小）。一半的扫描结果显示前磨牙区域有一个氧化锆种植体，而其他扫描结果显示前磨牙和臼齿区域有两个种植体。多平面重建分析考虑了三种重建厚度（0.125 毫米、1 毫米和 2 毫米）。五位口腔颌面部放射科医生采用 5 级评分法对种植体周围骨缺损的检测进行评估。采用双向方差分析（α = .05）计算和比较诊断参数。结果所研究的因素对种植体周围骨缺损的诊断无显著影响（p > .05）。单颗种植体的诊断率明显更高，尤其是重建厚度为 2 毫米时（AUC = 0.88，敏感性 = 0.68，特异性 = 0.94）。结论相邻氧化锆种植体的存在和重建厚度的变化不会影响 CBCT 图像对 3 毫米颊侧种植体周围骨缺损的检测。

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引用次数: 0

Clinical, radiographic and patient-reported outcomes of zirconia and titanium implants in the posterior zone after 1 year of loading—A randomized controlled trial 后区氧化锆和钛种植体植入 1 年后的临床、影像学和患者报告结果--随机对照试验。

IF 4.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Implants Research

Pub Date : 2024-07-26 DOI: 10.1111/clr.14329

Anina N. Zuercher, Marc Balmer, Lily V. Brügger, Daniel S. Thoma, Ronald E. Jung, Stefan P. Bienz

Objective

To assess the clinical, radiographic and patient-reported outcomes (PROMs) of posterior zirconia and titanium implants at 1 year of implant loading.

Materials and Methods

Forty-two patients with two adjacent missing teeth were enrolled in a randomized controlled trial with a within-subject controlled design. Each patient received one zirconia (Zr) and one titanium (Ti) implant, with the mesial and distal positions randomized. The implant restoration consisted of multiple layered zirconia, with the buccal aspect veneered. In group Zr, the restoration was intraorally cemented onto the one-piece Zr implant, whereas in group Ti, the restoration was extraorally cemented onto the titanium base abutment and intraorally screw-retained onto the Ti implant. Examinations were performed following restoration delivery at baseline (BL) and at 1 year. Measurements included clinical parameters, radiographic outcomes (MBL) and PROMs.

Results

Bleeding on probing showed an increase from BL to 1 year (34 ± 30% for Zr; 25 ± 21% for Ti). MBL remained stable with minimal changes from BL to 1 year, measuring 0.1 ± 0.4 mm (mean ± SD) for Zr and −0.1 ± 0.7 mm for Ti. Veneering fractures were the most frequent technical complication and amounted to 17.5% in group Zr and 5% in group Ti (p = .100). Patients preferred Zr implants for their soft tissue color, with a significant difference in perception between patients and clinicians (p < .017).

Conclusion

The study showed that both Zr and Ti implants had similar clinical outcomes, despite a high prevalence of mucositis and a few technical complications. Both implant types demonstrated stable marginal bone levels and similar patient-reported outcome measures.

目的评估后部氧化锆和钛种植体在植入一年后的临床、影像学和患者报告结果（PROMs）：42 名有两颗相邻缺失牙的患者参加了一项随机对照试验，试验采用受试者内对照设计。每位患者都接受了一颗氧化锆（Zr）和一颗钛（Ti）种植体，中远端位置随机。种植体修复体由多层氧化锆组成，颊侧贴面。在 Zr 组中，修复体在口腔内与一体式 Zr 种植体固位，而在 Ti 组中，修复体在口腔外与钛基台固位，在口腔内与 Ti 种植体用螺丝固位。修复体交付后，分别在基线（BL）和一年后进行检查。测量包括临床参数、放射学结果（MBL）和PROMs：结果：从基线到 1 年期间，探诊出血量有所增加（锆为 34 ± 30%；钛为 25 ± 21%）。MBL保持稳定，从BL到1年的变化很小，Zr为0.1 ± 0.4 mm（平均值± SD），Ti为-0.1 ± 0.7 mm。贴面骨折是最常见的技术并发症，Zr 组为 17.5%，Ti 组为 5%（p = .100）。患者更喜欢 Zr 种植体的软组织颜色，但患者和临床医生的看法存在显著差异（p 结论：Zr 和 Ti 种植体的软组织颜色都比 Zr 种植体好：研究表明，尽管粘膜炎的发病率较高且存在一些技术并发症，但锆和钛种植体的临床效果相似。两种类型的种植体都表现出稳定的边缘骨水平和相似的患者报告结果。

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引用次数: 0

A cross-sectional CBCT assessment of the relative position of one-piece titanium-zirconium mini-implants placed for mandibular overdentures using non-guided surgery 使用非引导手术对下颌覆盖义齿植入的一体式钛锆迷你植入体的相对位置进行横截面 CBCT 评估。

IF 4.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Implants Research

Pub Date : 2024-07-23 DOI: 10.1111/clr.14335

Cláudio Rodrigues Leles, Leuçon de Oliveira Moura-Neto, Jésio Rodrigues Silva, Lays Noleto Nascimento, Thalita Fernandes Fleury Curado, Nadia Lago Costa, Martin Schimmel, Gerald McKenna

Objective

To assess the relative position of mini-implants to retain a mandibular overdenture, according to the surgical protocol, technical and anatomical factors.

Methods

Mandibular cone-beam computed tomography (CBCT) scans were analyzed for 73 patients who received four one-piece titanium-zirconium mini-implants. Drilling was performed using a 1.6 mm needle drill and a 2.2 mm Pilot Drill, according to the bone density with a surgical stent. Post-insertion CBCT images in DICOM format were analyzed using the E-Vol-DX software with BAR filters. Divergence angle between implants and between implants and the overdenture path of insertion was measured using CliniView 10.2.6 software.

Results

Divergence between implants ranged from 0° to 22.3° (mean = 4.2; SD = 3.7) in the lateral and from 0° to 26.2° (mean = 5.3; SD = 4.1) in the frontal projections (p < .001). Only 1 (0.2%) and 3 (0.7%) of the measurements were higher than 20° in the lateral and frontal views, respectively. The mean angulations between the implant and the path of insertion for the overdenture were 9.3° (SD = 7.5) and 4.0° (SD = 2.9) for the lateral and frontal views, respectively (p < .001). Regression analyses showed a significant association between the divergence of implants and the frontal view projection (p < .001), greater distance between the paired implants (p = .017), the flapped surgical protocol (p = .002), higher final insertion torque (p = .011), and deeper preparation with the needle drill (p < .001).

Conclusions

The mini-implants were placed with low divergence angles and satisfactory parallelism. Factors including shorter distances between the implants, higher density bone, and a flapless surgical approach all contributed positively to improved parallelism of the mini-implants.

目的根据手术方案、技术和解剖因素，评估微型种植体保留下颌覆盖义齿的相对位置：对 73 名接受了四颗一体式钛锆迷你种植体的患者的下颌锥形束计算机断层扫描（CBCT）进行分析。根据骨密度使用 1.6 毫米针钻和 2.2 毫米先导钻进行钻孔，并使用手术支架。使用带有 BAR 过滤器的 E-Vol-DX 软件对 DICOM 格式的植入后 CBCT 图像进行了分析。使用 CliniView 10.2.6 软件测量了种植体之间以及种植体与覆盖义齿插入路径之间的发散角：结果：种植体之间的偏离角度在侧面投影中为 0°至 22.3°（平均值 = 4.2；标度 = 3.7），在正面投影中为 0°至 26.2°（平均值 = 5.3；标度 = 4.1）（P 结论：种植体之间的偏离角度在侧面投影中为 0°至 22.3°（平均值 = 4.2；标度 = 3.7），在正面投影中为 0°至 26.2°（平均值 = 5.3；标度 = 4.1）：微型种植体植入后的发散角小，平行度令人满意。种植体之间的距离较短、骨密度较高以及无瓣手术方法等因素都有助于改善微型种植体的平行度。

{"title":"A cross-sectional CBCT assessment of the relative position of one-piece titanium-zirconium mini-implants placed for mandibular overdentures using non-guided surgery","authors":"Cláudio Rodrigues Leles, Leuçon de Oliveira Moura-Neto, Jésio Rodrigues Silva, Lays Noleto Nascimento, Thalita Fernandes Fleury Curado, Nadia Lago Costa, Martin Schimmel, Gerald McKenna","doi":"10.1111/clr.14335","DOIUrl":"10.1111/clr.14335","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To assess the relative position of mini-implants to retain a mandibular overdenture, according to the surgical protocol, technical and anatomical factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Mandibular cone-beam computed tomography (CBCT) scans were analyzed for 73 patients who received four one-piece titanium-zirconium mini-implants. Drilling was performed using a 1.6 mm needle drill and a 2.2 mm Pilot Drill, according to the bone density with a surgical stent. Post-insertion CBCT images in DICOM format were analyzed using the E-Vol-DX software with BAR filters. Divergence angle between implants and between implants and the overdenture path of insertion was measured using CliniView 10.2.6 software.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Divergence between implants ranged from 0° to 22.3° (mean = 4.2; SD = 3.7) in the lateral and from 0° to 26.2° (mean = 5.3; SD = 4.1) in the frontal projections (<i>p</i> < .001). Only 1 (0.2%) and 3 (0.7%) of the measurements were higher than 20° in the lateral and frontal views, respectively. The mean angulations between the implant and the path of insertion for the overdenture were 9.3° (SD = 7.5) and 4.0° (SD = 2.9) for the lateral and frontal views, respectively (<i>p</i> < .001). Regression analyses showed a significant association between the divergence of implants and the frontal view projection (<i>p</i> < .001), greater distance between the paired implants (<i>p</i> = .017), the flapped surgical protocol (<i>p</i> = .002), higher final insertion torque (<i>p</i> = .011), and deeper preparation with the needle drill (<i>p</i> < .001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The mini-implants were placed with low divergence angles and satisfactory parallelism. Factors including shorter distances between the implants, higher density bone, and a flapless surgical approach all contributed positively to improved parallelism of the mini-implants.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"35 11","pages":"1475-1484"},"PeriodicalIF":4.8,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.14335","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bone volume and height changes for lateral window sinus floor elevation using two types of deproteinized bovine bone mineral: A retrospective cohort study of 1–4 years 使用两种去蛋白牛骨矿物质抬高侧窗窦底的骨量和高度变化：一项为期 1-4 年的回顾性队列研究。

IF 4.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Implants Research

Pub Date : 2024-07-23 DOI: 10.1111/clr.14337

Pei Xiao, Cong Chen, Xiaoting Shen, Antian Xu, Mufeed Ahmed Sharaf, Hongye Lu, Fuming He

Objective

To compare bone volume and height changes of two types of deproteinized bovine bone mineral (DBBM) for lateral window sinus floor elevation (LSFE) with simultaneous implant placement.

Materials and Methods

This retrospective cohort study involved 72 patients who underwent LSFE using low-temperature sintered cancellous bone-derived DBBM (C-DBBM) or high-temperature two-step sintered epiphyseal-derived DBBM (E-DBBM). Cone-beam computed tomography (CBCT) was acquired preoperatively, immediately postoperatively, 6 months and 1–4 years post-surgery. Bone volume (BV), apical bone height (ABH), endo-sinus bone gain (ESBG), and crestal bone level (CBL) were evaluated through three-dimensional fitting and superimposition. Linear mixed models (LMM) were employed to analyze factors influencing the reduction of BV (ΔBV) and ESBG (ΔESBG).

Results

The E-DBBM group showed no significant change in BV 1–4 years post-surgery, while the C-DBBM group demonstrated a significant reduction (p = .006) with volume stability of 85.86%. Bone height in the E-DBBM group increased at 6 months and subsequently decreased at 1–4 years (p = .003). In the C-DBBM group, it decreased at 6 months (p = .014), then further decreased at 1–4 years (p = .001). ΔESBG was lower in the E-DBBM group than the C-DBBM group from immediate postoperative to 1–4 years (p = .009). LMM showed graft material type was the primary factor influencing ΔBV (p = .026) and ΔESBG (p = .003).

Conclusions

Within the limitations of this study, both types of DBBM could achieve favorable clinical outcomes. E-DBBM demonstrated enhanced stability in maintaining bone volume and height.

摘要比较两种类型的去蛋白牛骨矿物质（DBBM）用于侧窗窦底抬高术（LSFE）并同时植入种植体的骨量和高度变化：这项回顾性队列研究涉及 72 例使用低温烧结松质骨衍生 DBBM（C-DBBM）或高温两步烧结骺端衍生 DBBM（E-DBBM）进行 LSFE 的患者。分别在术前、术后即刻、术后 6 个月和术后 1-4 年进行锥形束计算机断层扫描（CBCT）。通过三维拟合和叠加评估了骨量（BV）、根尖骨高（ABH）、窦内骨增量（ESBG）和嵴骨水平（CBL）。采用线性混合模型（LMM）分析影响 BV（ΔBV）和 ESBG（ΔESBG）降低的因素：结果：E-DBBM组术后1-4年的BV无明显变化，而C-DBBM组显著降低（p = .006），体积稳定率为85.86%。E-DBBM 组的骨高在 6 个月时增加，随后在 1-4 年时降低（p = .003）。C-DBBM 组的骨高在 6 个月时降低（p = .014），然后在 1-4 年时进一步降低（p = .001）。从术后即刻到 1-4 年，E-DBBM 组的ΔESBG 低于 C-DBBM 组（p = .009）。LMM显示移植物材料类型是影响ΔBV（p = .026）和ΔESBG（p = .003）的主要因素：结论：在本研究的限制条件下，两种类型的 DBBM 都能获得良好的临床效果。E-DBBM在维持骨量和骨高方面表现出更强的稳定性。

{"title":"Bone volume and height changes for lateral window sinus floor elevation using two types of deproteinized bovine bone mineral: A retrospective cohort study of 1–4 years","authors":"Pei Xiao, Cong Chen, Xiaoting Shen, Antian Xu, Mufeed Ahmed Sharaf, Hongye Lu, Fuming He","doi":"10.1111/clr.14337","DOIUrl":"10.1111/clr.14337","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To compare bone volume and height changes of two types of deproteinized bovine bone mineral (DBBM) for lateral window sinus floor elevation (LSFE) with simultaneous implant placement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>This retrospective cohort study involved 72 patients who underwent LSFE using low-temperature sintered cancellous bone-derived DBBM (C-DBBM) or high-temperature two-step sintered epiphyseal-derived DBBM (E-DBBM). Cone-beam computed tomography (CBCT) was acquired preoperatively, immediately postoperatively, 6 months and 1–4 years post-surgery. Bone volume (BV), apical bone height (ABH), endo-sinus bone gain (ESBG), and crestal bone level (CBL) were evaluated through three-dimensional fitting and superimposition. Linear mixed models (LMM) were employed to analyze factors influencing the reduction of BV (ΔBV) and ESBG (ΔESBG).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The E-DBBM group showed no significant change in BV 1–4 years post-surgery, while the C-DBBM group demonstrated a significant reduction (<i>p</i> = .006) with volume stability of 85.86%. Bone height in the E-DBBM group increased at 6 months and subsequently decreased at 1–4 years (<i>p</i> = .003). In the C-DBBM group, it decreased at 6 months (<i>p</i> = .014), then further decreased at 1–4 years (<i>p</i> = .001). ΔESBG was lower in the E-DBBM group than the C-DBBM group from immediate postoperative to 1–4 years (<i>p</i> = .009). LMM showed graft material type was the primary factor influencing ΔBV (<i>p</i> = .026) and ΔESBG (<i>p</i> = .003).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Within the limitations of this study, both types of DBBM could achieve favorable clinical outcomes. E-DBBM demonstrated enhanced stability in maintaining bone volume and height.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"35 11","pages":"1493-1505"},"PeriodicalIF":4.8,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative osseointegration of hydrophobic tissue-level tapered implants—A preclinical in vivo study 疏水性组织级锥形植入物的骨结合对比--临床前体内研究

IF 4.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Implants Research

Pub Date : 2024-07-20 DOI: 10.1111/clr.14318

Jean-Claude Imber, Azita Khandanpour, Andrea Roccuzzo, Delia R. Irani, Dieter D. Bosshardt, Anton Sculean, Benjamin E. Pippenger

Purpose

To histometrically compare the osseointegration and crestal bone healing of a novel tapered, self-cutting tissue-level test implant with a standard tissue-level control implant in a submerged healing regimen.

Materials and Methods

In a mandibular minipig model, implants were inserted and evaluated histometrically after a healing period of 3, 6, and 12 weeks. The primary outcome was the evaluation of bone-to-implant contact (BIC) and secondary outcomes were primary stability as per insertion torque and first BIC (fBIC). Outcomes for the test and control implants were compared using Wilcoxon signed-rank tests and mixed linear regression models.

Results

Insertion torque values were significantly higher for the test (50.0 ± 26.4 Ncm) compared to the control implants (35.2 ± 19.7 Ncm, p = .0071). BIC values of test implants were non-inferior to those of control implants over the investigated study period. After 12 weeks, the corresponding values measured were 81.62 ± 11.12% and 90.41 ± 4.81% (p = .1763) for test and control implants, respectively. Similarly, no statistical difference was found for fBIC values, except for the 12 weeks outcome that showed statistically lower values for the test (−675.58 ± 590.88 μm) compared to control implants (−182.75 ± 197.40 μm, p = .0068).

Conclusions

Novel self-cutting tissue-level implants demonstrated noninferior osseointegration and crestal bone height maintenance to the tissue-level implants. Histometric outcomes between both implants demonstrated test implants were statistically noninferior to control implants, despite substantial differences in the bone engagement mechanism and resulting differences in insertion torque and qualitative bone healing patterns.

目的比较新型锥形自切组织水平试验种植体与标准组织水平对照种植体在水下愈合过程中的骨结合和骨嵴愈合情况。主要结果是骨与种植体接触（BIC）的评估，次要结果是根据插入扭矩和首次骨与种植体接触（fBIC）计算的主要稳定性。使用 Wilcoxon 符号秩检验和混合线性回归模型对试验种植体和对照种植体的结果进行比较。结果试验种植体的插入扭矩值（50.0 ± 26.4 Ncm）明显高于对照种植体（35.2 ± 19.7 Ncm，p = .0071）。在研究期间，试验种植体的 BIC 值与对照种植体相比没有劣势。12 周后，测试种植体和对照种植体的相应测量值分别为 81.62 ± 11.12% 和 90.41 ± 4.81%（p = .1763）。同样，fBIC 值也没有发现统计学差异，只是在 12 周后，测试值（-675.58 ± 590.88 μm）低于对照种植体（-182.75 ± 197.40 μm，p = .0068）。两种种植体之间的组织计量结果表明，尽管骨啮合机制存在很大差异，导致插入扭矩和骨愈合模式的不同，但从统计学角度来看，试验种植体并不逊色于对照种植体。

{"title":"Comparative osseointegration of hydrophobic tissue-level tapered implants—A preclinical in vivo study","authors":"Jean-Claude Imber, Azita Khandanpour, Andrea Roccuzzo, Delia R. Irani, Dieter D. Bosshardt, Anton Sculean, Benjamin E. Pippenger","doi":"10.1111/clr.14318","DOIUrl":"10.1111/clr.14318","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>To histometrically compare the osseointegration and crestal bone healing of a novel tapered, self-cutting tissue-level test implant with a standard tissue-level control implant in a submerged healing regimen.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>In a mandibular minipig model, implants were inserted and evaluated histometrically after a healing period of 3, 6, and 12 weeks. The primary outcome was the evaluation of bone-to-implant contact (BIC) and secondary outcomes were primary stability as per insertion torque and first BIC (fBIC). Outcomes for the test and control implants were compared using Wilcoxon signed-rank tests and mixed linear regression models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Insertion torque values were significantly higher for the test (50.0 ± 26.4 Ncm) compared to the control implants (35.2 ± 19.7 Ncm, <i>p</i> = .0071). BIC values of test implants were non-inferior to those of control implants over the investigated study period. After 12 weeks, the corresponding values measured were 81.62 ± 11.12% and 90.41 ± 4.81% (<i>p</i> = .1763) for test and control implants, respectively. Similarly, no statistical difference was found for fBIC values, except for the 12 weeks outcome that showed statistically lower values for the test (−675.58 ± 590.88 μm) compared to control implants (−182.75 ± 197.40 μm, <i>p =</i> .0068).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Novel self-cutting tissue-level implants demonstrated noninferior osseointegration and crestal bone height maintenance to the tissue-level implants. Histometric outcomes between both implants demonstrated test implants were statistically noninferior to control implants, despite substantial differences in the bone engagement mechanism and resulting differences in insertion torque and qualitative bone healing patterns.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"35 10","pages":"1299-1309"},"PeriodicalIF":4.8,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.14318","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141730518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0