Ethan Ng,John Rong Hao Tay,Maria Rahmat,Luis Mezzomo,Gil Alcoforado,Nikos Donos
OBJECTIVESTo evaluate the prosthetic outcomes of implant-assisted maxillary full-arch restorations with ≥ 3 years of follow-up.MATERIALS AND METHODSA systematic electronic literature search was conducted in five databases to identify randomised controlled trials and prospective clinical studies involving patients who received full-arch rehabilitation in the maxilla. The primary outcome was prosthesis loss; secondary outcomes included complication-free prosthesis survival, complication-free implant survival, implant loss, technical complications, patient-reported outcome measures (PROMS), and marginal bone loss. Meta-analyses of proportions using random-effects models were performed to estimate pooled rates of prosthetic survival, success, and complications.RESULTSA total of 20 studies involving 913 patients were included. Among these, 542 patients received fixed prostheses and 371 received removable prostheses. Most of the studies had an observation period in the range of 3 to 6 years, with only two studies (overdentures) reaching 10 years. Overall prosthesis loss was 4.6% (95% CI: 1.2%-10.1%) and complication-free prosthesis survival was 61.9% (95% CI: 48.4%-74.5%). Overall complication-free implant survival was 46.5% and technical complications were 62.9%. Pooled implant loss was 5.5% after adjusting for clustering effects and mean marginal bone loss was < 0.8 mm. Subgroup analysis of fixed and removable prosthesis over a similar observation period revealed similar outcomes.CONCLUSIONSImplant-assisted maxillary full-arch restorations have low rates of prosthesis and implant loss. However, complication-free survival is moderate, underscoring the importance of maintenance and patient education.
{"title":"Prosthetic Outcomes of Implant-Assisted Maxillary Restorations in the Edentulous Maxilla: A Systematic Review and Meta-Analysis.","authors":"Ethan Ng,John Rong Hao Tay,Maria Rahmat,Luis Mezzomo,Gil Alcoforado,Nikos Donos","doi":"10.1111/clr.70116","DOIUrl":"https://doi.org/10.1111/clr.70116","url":null,"abstract":"OBJECTIVESTo evaluate the prosthetic outcomes of implant-assisted maxillary full-arch restorations with ≥ 3 years of follow-up.MATERIALS AND METHODSA systematic electronic literature search was conducted in five databases to identify randomised controlled trials and prospective clinical studies involving patients who received full-arch rehabilitation in the maxilla. The primary outcome was prosthesis loss; secondary outcomes included complication-free prosthesis survival, complication-free implant survival, implant loss, technical complications, patient-reported outcome measures (PROMS), and marginal bone loss. Meta-analyses of proportions using random-effects models were performed to estimate pooled rates of prosthetic survival, success, and complications.RESULTSA total of 20 studies involving 913 patients were included. Among these, 542 patients received fixed prostheses and 371 received removable prostheses. Most of the studies had an observation period in the range of 3 to 6 years, with only two studies (overdentures) reaching 10 years. Overall prosthesis loss was 4.6% (95% CI: 1.2%-10.1%) and complication-free prosthesis survival was 61.9% (95% CI: 48.4%-74.5%). Overall complication-free implant survival was 46.5% and technical complications were 62.9%. Pooled implant loss was 5.5% after adjusting for clustering effects and mean marginal bone loss was < 0.8 mm. Subgroup analysis of fixed and removable prosthesis over a similar observation period revealed similar outcomes.CONCLUSIONSImplant-assisted maxillary full-arch restorations have low rates of prosthesis and implant loss. However, complication-free survival is moderate, underscoring the importance of maintenance and patient education.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"17 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147471559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Víctor Ruiz‐Romero, Octavi Camps‐Font, Adria Jorba‐Garcia, Alba Sánchez‐Torres, Rui Figueiredo, Eduard Valmaseda‐Castellón
Objectives To compare the trueness of implant placement in novice surgeons using dynamic computer‐assisted implant surgery (d‐CAIS) versus a non‐guided approach, assessing surgery time efficiency and patient‐reported outcomes, including satisfaction, postoperative pain, and quality of life. Material and Methods A double‐arm randomized clinical trial was conducted. Consecutive partially edentulous patients were randomly assigned to d‐CAIS or non‐guided. Trueness outcomes, including apex and platform linear deviation (mm) and angular deviation (degrees), were measured by superimposing pre‐ and postoperative CBCT scans. Pre‐ and postoperative questionnaires assessed patient self‐reported satisfaction and quality of life during surgery and in the postoperative period. Results Sixty patients (72 implants) were included. Thirty patients received 36 implants using d‐CAIS, while another 30 patients received 36 implants with the non‐guided technique. d‐CAIS significantly reduced angular (MD: −5.51°; p < 0.001), lateral platform (MD: −0.79 mm; p = 0.037), global platform (MD: −0.89 mm; p = 0.024), and global apex deviations (MD: −1.23 mm; p = 0.001). Although the implant placement time was significantly shorter with d‐CAIS ( p = 0.022), there was no statistically significant difference in overall surgery time between the groups (MD: −6.18 min; p = 0.190). Postoperative pain and analgesic consumption were similar, with high self‐reported satisfaction. The surgical procedure did not result in significant changes in patient quality of life. Conclusions Implant placement using d‐CAIS by novice surgeons shows higher trueness, without increasing surgery time. It also ensures high patient satisfaction and quality of life, with pain levels comparable to those of the non‐guided technique. ClinicalTrials.gov registration number: NCT06028750.
目的比较使用动态计算机辅助种植手术(d - CAIS)与非引导方法的新手外科医生种植体放置的准确性,评估手术时间效率和患者报告的结果,包括满意度、术后疼痛和生活质量。材料和方法进行了一项双组随机临床试验。连续部分无牙患者被随机分配到d - CAIS或非引导组。准确性结果,包括顶点和平台线性偏差(mm)和角偏差(度),通过叠加术前和术后CBCT扫描来测量。术前和术后问卷评估患者在手术期间和术后自我报告的满意度和生活质量。结果共纳入60例患者(72颗种植体)。30例患者使用d - CAIS植入36个种植体,另外30例患者使用非引导技术植入36个种植体。d‐CAIS显著降低了角度(MD:−5.51°;p < 0.001)、横向平台(MD:−0.79 mm; p = 0.037)、全局平台(MD:−0.89 mm; p = 0.024)和全局顶点偏差(MD:−1.23 mm; p = 0.001)。虽然d‐CAIS组种植体放置时间明显缩短(p = 0.022),但两组间总手术时间差异无统计学意义(MD: - 6.18 min; p = 0.190)。术后疼痛和镇痛药用量相似,自我报告满意度高。手术过程没有导致患者生活质量的显著改变。结论新手使用d - CAIS植入物具有较高的正确率,且不增加手术时间。它还确保了高患者满意度和生活质量,疼痛水平与非引导技术相当。ClinicalTrials.gov注册号:NCT06028750。
{"title":"Trueness of Dental Implant Placement Using Dynamic Navigation or Non‐Guided Approach by Novice Surgeons: A Randomized, Controlled Clinical Trial","authors":"Víctor Ruiz‐Romero, Octavi Camps‐Font, Adria Jorba‐Garcia, Alba Sánchez‐Torres, Rui Figueiredo, Eduard Valmaseda‐Castellón","doi":"10.1111/clr.70119","DOIUrl":"https://doi.org/10.1111/clr.70119","url":null,"abstract":"Objectives To compare the trueness of implant placement in novice surgeons using dynamic computer‐assisted implant surgery (d‐CAIS) versus a non‐guided approach, assessing surgery time efficiency and patient‐reported outcomes, including satisfaction, postoperative pain, and quality of life. Material and Methods A double‐arm randomized clinical trial was conducted. Consecutive partially edentulous patients were randomly assigned to d‐CAIS or non‐guided. Trueness outcomes, including apex and platform linear deviation (mm) and angular deviation (degrees), were measured by superimposing pre‐ and postoperative CBCT scans. Pre‐ and postoperative questionnaires assessed patient self‐reported satisfaction and quality of life during surgery and in the postoperative period. Results Sixty patients (72 implants) were included. Thirty patients received 36 implants using d‐CAIS, while another 30 patients received 36 implants with the non‐guided technique. d‐CAIS significantly reduced angular (MD: −5.51°; <jats:italic>p</jats:italic> < 0.001), lateral platform (MD: −0.79 mm; <jats:italic>p</jats:italic> = 0.037), global platform (MD: −0.89 mm; <jats:italic>p</jats:italic> = 0.024), and global apex deviations (MD: −1.23 mm; <jats:italic>p</jats:italic> = 0.001). Although the implant placement time was significantly shorter with d‐CAIS ( <jats:italic>p</jats:italic> = 0.022), there was no statistically significant difference in overall surgery time between the groups (MD: −6.18 min; <jats:italic>p</jats:italic> = 0.190). Postoperative pain and analgesic consumption were similar, with high self‐reported satisfaction. The surgical procedure did not result in significant changes in patient quality of life. Conclusions Implant placement using d‐CAIS by novice surgeons shows higher trueness, without increasing surgery time. It also ensures high patient satisfaction and quality of life, with pain levels comparable to those of the non‐guided technique. ClinicalTrials.gov registration number: NCT06028750.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"527 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147465370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OBJECTIVESThis study aimed to investigate patient-related and prosthetic factors associated with peri-implant marginal bone loss (MBL) in patients receiving supportive periodontal therapy (SPT).MATERIALS AND METHODSThis retrospective cohort study included patients who underwent implant treatment and continued SPT for at least 10 years. MBL was evaluated using standardized dental radiographs obtained at baseline (1 year after prosthesis placement) and at follow-up (over 10 years after baseline). Patient-related factors (age, sex, history of diabetes mellitus, history of periodontitis, plaque control record [PCR], smoking, parafunctional habits, jaw position, and keratinized mucosa width [KMW]) and prosthetic factors (number of occlusal supports, fixation type, connection type, splinting, emergence profile [EP], and emergence angle [EA]) were analyzed. A standard linear mixed model assuming a normal distribution and identity link was applied, with patient and clinician as random effects.RESULTSData from 192 patients (600 implants) were analyzed in this study. Significant associations with MBL were observed for history of diabetes mellitus (p < 0.001), history of periodontitis (p = 0.027), fewer occlusal supports (p = 0.002), mandibular location (p = 0.002), KMW < 2 mm (p = 0.021), cement-retained prosthesis (p < 0.001), EA ≥ 30° (p = 0.006), and implant-abutment joint type (p = 0.021). PCR (p = 0.506) and smoking (p = 0.720) were not significantly associated with MBL.CONCLUSIONSIn patients receiving SPT, history of diabetes, history of periodontitis, jaw position, insufficient KMW, and prosthetic features such as EA and fixation type were associated with MBL.
{"title":"Risk Factors Associated With Peri-Implant Marginal Bone Loss Among Japanese Patients Receiving Supportive Periodontal Therapy: A 10-Year Retrospective Study.","authors":"Daisuke Hasegawa,Tomoaki Mameno,Masahiro Wada,Yuichi Nishimura,Takeshi Kikuchi,Yoshinobu Onodera,Giovanni Serino,Kazunori Ikebe","doi":"10.1111/clr.70114","DOIUrl":"https://doi.org/10.1111/clr.70114","url":null,"abstract":"OBJECTIVESThis study aimed to investigate patient-related and prosthetic factors associated with peri-implant marginal bone loss (MBL) in patients receiving supportive periodontal therapy (SPT).MATERIALS AND METHODSThis retrospective cohort study included patients who underwent implant treatment and continued SPT for at least 10 years. MBL was evaluated using standardized dental radiographs obtained at baseline (1 year after prosthesis placement) and at follow-up (over 10 years after baseline). Patient-related factors (age, sex, history of diabetes mellitus, history of periodontitis, plaque control record [PCR], smoking, parafunctional habits, jaw position, and keratinized mucosa width [KMW]) and prosthetic factors (number of occlusal supports, fixation type, connection type, splinting, emergence profile [EP], and emergence angle [EA]) were analyzed. A standard linear mixed model assuming a normal distribution and identity link was applied, with patient and clinician as random effects.RESULTSData from 192 patients (600 implants) were analyzed in this study. Significant associations with MBL were observed for history of diabetes mellitus (p < 0.001), history of periodontitis (p = 0.027), fewer occlusal supports (p = 0.002), mandibular location (p = 0.002), KMW < 2 mm (p = 0.021), cement-retained prosthesis (p < 0.001), EA ≥ 30° (p = 0.006), and implant-abutment joint type (p = 0.021). PCR (p = 0.506) and smoking (p = 0.720) were not significantly associated with MBL.CONCLUSIONSIn patients receiving SPT, history of diabetes, history of periodontitis, jaw position, insufficient KMW, and prosthetic features such as EA and fixation type were associated with MBL.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"2 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147461778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shengtao Yang,Chenyi Zhang,Yan Bao,Shuo Wang,Lei Chi,Li Yue,Quan Yuan,Junying Li
OBJECTIVESTo introduce a universal scan calibrator (SC) and to evaluate its accuracy in the calibrated intraoral scan protocol (CISP) by comparison with two previously published SCs.MATERIALS AND METHODSThree SCs were evaluated on an edentulous implant model containing six scan bodies (SBs) positioned at the screw-retained abutment (SRA) level: (1) a universal SC with a C-shaped window (SC-CW), (2) an SC covering only the alveolar ridge (SC-R), and (3) an SC limited to the palatal region (SC-P). Each SC was attached to the model and scanned 10 times using an intraoral scanner (IOS). The intraoral scans were subsequently corrected using the corresponding desktop scans of the SCs as reference data. A desktop scan of the model served as the reference. The test scans were superimposed onto the reference scan by: (1) using all SBs to evaluate the overall fit, and (2) using the first and second SBs to simulate the virtual Sheffield test. Linear and angular deviations of SRAs were measured using Python scripts.RESULTSWhen aligned by all SBs, all three groups exhibited significant improvements in trueness and linear precision following correction. In the virtual Sheffield test, no statistically significant differences were observed in post-correction trueness or angular precision at the ending SRA6. All three groups achieved clinically acceptable trueness and precision values following correction.CONCLUSIONSAll three SCs yielded clinically acceptable impressions after correction under in vitro conditions. The novel SC represents a promising approach for CISP; however, further in vivo clinical evidence is required.
{"title":"Accuracy (Trueness and Precision) of the Calibrated Intraoral Scan Protocol: An In Vitro Comparison of Three Scan Calibrator Designs In an Edentulous Implant Model.","authors":"Shengtao Yang,Chenyi Zhang,Yan Bao,Shuo Wang,Lei Chi,Li Yue,Quan Yuan,Junying Li","doi":"10.1111/clr.70117","DOIUrl":"https://doi.org/10.1111/clr.70117","url":null,"abstract":"OBJECTIVESTo introduce a universal scan calibrator (SC) and to evaluate its accuracy in the calibrated intraoral scan protocol (CISP) by comparison with two previously published SCs.MATERIALS AND METHODSThree SCs were evaluated on an edentulous implant model containing six scan bodies (SBs) positioned at the screw-retained abutment (SRA) level: (1) a universal SC with a C-shaped window (SC-CW), (2) an SC covering only the alveolar ridge (SC-R), and (3) an SC limited to the palatal region (SC-P). Each SC was attached to the model and scanned 10 times using an intraoral scanner (IOS). The intraoral scans were subsequently corrected using the corresponding desktop scans of the SCs as reference data. A desktop scan of the model served as the reference. The test scans were superimposed onto the reference scan by: (1) using all SBs to evaluate the overall fit, and (2) using the first and second SBs to simulate the virtual Sheffield test. Linear and angular deviations of SRAs were measured using Python scripts.RESULTSWhen aligned by all SBs, all three groups exhibited significant improvements in trueness and linear precision following correction. In the virtual Sheffield test, no statistically significant differences were observed in post-correction trueness or angular precision at the ending SRA6. All three groups achieved clinically acceptable trueness and precision values following correction.CONCLUSIONSAll three SCs yielded clinically acceptable impressions after correction under in vitro conditions. The novel SC represents a promising approach for CISP; however, further in vivo clinical evidence is required.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"16 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147454344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AIMTo evaluate the prevalence and risk indicators of peri-implant diseases in a randomly selected Chinese population.MATERIALS AND METHODSA total of 819 patients with 1412 implants from eight university hospital databases were clinically and radiographically evaluated along with medical records to assess the prevalence of peri-implant diseases. Potential risk/protective indicators were explored using multilevel mixed-effects logistic regression analysis.RESULTSAccording to the 2017 EFP/AAP World Workshop case definitions, the prevalence of peri-implant mucositis at the subject and implant level was 36.4% and 31.3%, respectively. The prevalence of peri-implantitis at the subject and implant level was 4% and 3.3%, respectively. History of periodontitis and heavy smoking were identified as risk indicators for peri-implantitis in the final model.CONCLUSIONIn this randomly selected diverse patient sample within China, the prevalence of peri-implant diseases was moderately high (40.4%) after a mean follow-up duration of 6.65 ± 1.18 years post loading.
{"title":"Prevalence and Risk Indicators of Peri-Implant Diseases in China: A Multicenter Cross-Sectional Study.","authors":"Xinbo Yu,Feng Wang,Dongning He,Jinming Wang,Runfa Wu,Dayong Zhang,Qin Fan,Haibin Xia,Zhe Qu,Yiqun Wu","doi":"10.1111/clr.70118","DOIUrl":"https://doi.org/10.1111/clr.70118","url":null,"abstract":"AIMTo evaluate the prevalence and risk indicators of peri-implant diseases in a randomly selected Chinese population.MATERIALS AND METHODSA total of 819 patients with 1412 implants from eight university hospital databases were clinically and radiographically evaluated along with medical records to assess the prevalence of peri-implant diseases. Potential risk/protective indicators were explored using multilevel mixed-effects logistic regression analysis.RESULTSAccording to the 2017 EFP/AAP World Workshop case definitions, the prevalence of peri-implant mucositis at the subject and implant level was 36.4% and 31.3%, respectively. The prevalence of peri-implantitis at the subject and implant level was 4% and 3.3%, respectively. History of periodontitis and heavy smoking were identified as risk indicators for peri-implantitis in the final model.CONCLUSIONIn this randomly selected diverse patient sample within China, the prevalence of peri-implant diseases was moderately high (40.4%) after a mean follow-up duration of 6.65 ± 1.18 years post loading.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"56 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147447018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maurício G Araújo,Debora R Dias,Ping Wang,Robert A Levine
OBJECTIVESTo evaluate the effect of the width of the buccal gap on the alveolar process reduction after immediate implant placement (IIP) at maxillary central incisor sites, compared to contralateral pristine tooth sites.MATERIAL AND METHODSTwenty-eight subjects who were treated with IIP to replace a maxillary central incisor and presented a pristine contralateral tooth site were included in this retrospective cohort study. The width of the gap between the implant and the inner walls of the socket was measured and grafted with deproteinized bovine bone mineral (DBBM). Subjects were divided into 2 groups: wide gap: > 2 mm (n = 14); Narrow gap: ≤ 2 mm (n = 14). CBCT scans were obtained after a mean follow-up of 6 (± 4) years and evaluated by a calibrated examiner. Dimensional measurements of the healed alveolar ridge (implant site) and alveolar process (tooth site) were compared between the two groups.RESULTSThe Narrow gap group showed significantly greater ridge resorption (41.1% ± 20.2%) in relation to the corresponding pristine tooth sites than the wide gap group (8.5% ± 11%). The width of the alveolar ridge at 3 and 5 mm below the crest and the height of the buccal wall were also significantly reduced in the narrow gap group.CONCLUSIONSA buccal gap > 2-mm wide grafted with DBBM after IIP may preserve more than 90% of the dimensions of the alveolar process. Conversely, a grafted narrow gap frequently results in significantly reduced ridge preservation.
{"title":"Effect of the Buccal Gap Width on Alveolar Process Reduction Following Immediate Implant Placement: A Retrospective CBCT Study.","authors":"Maurício G Araújo,Debora R Dias,Ping Wang,Robert A Levine","doi":"10.1111/clr.70106","DOIUrl":"https://doi.org/10.1111/clr.70106","url":null,"abstract":"OBJECTIVESTo evaluate the effect of the width of the buccal gap on the alveolar process reduction after immediate implant placement (IIP) at maxillary central incisor sites, compared to contralateral pristine tooth sites.MATERIAL AND METHODSTwenty-eight subjects who were treated with IIP to replace a maxillary central incisor and presented a pristine contralateral tooth site were included in this retrospective cohort study. The width of the gap between the implant and the inner walls of the socket was measured and grafted with deproteinized bovine bone mineral (DBBM). Subjects were divided into 2 groups: wide gap: > 2 mm (n = 14); Narrow gap: ≤ 2 mm (n = 14). CBCT scans were obtained after a mean follow-up of 6 (± 4) years and evaluated by a calibrated examiner. Dimensional measurements of the healed alveolar ridge (implant site) and alveolar process (tooth site) were compared between the two groups.RESULTSThe Narrow gap group showed significantly greater ridge resorption (41.1% ± 20.2%) in relation to the corresponding pristine tooth sites than the wide gap group (8.5% ± 11%). The width of the alveolar ridge at 3 and 5 mm below the crest and the height of the buccal wall were also significantly reduced in the narrow gap group.CONCLUSIONSA buccal gap > 2-mm wide grafted with DBBM after IIP may preserve more than 90% of the dimensions of the alveolar process. Conversely, a grafted narrow gap frequently results in significantly reduced ridge preservation.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"8 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147439548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shunhao Zhang,Mi Zhou,Yuxuan Zhao,Wen Chen,Xiaoxiao Cai
OBJECTIVESTo evaluate placement error, bone regeneration, and mesh exposure of three-dimensionally printed customized titanium mesh (3DPC Ti-mesh) guided by a vacuum-formed placing template in guided bone regeneration (GBR) for anterior maxillary defects.MATERIAL AND METHODS10 patients (23 implants) with Terheyden 2/4 or 3/4 defects were included. CBCT data of pre-operation (T0), immediate post-operation (T2), and 5-8 months post-operation (T3) were reconstructed. These three models and preoperative design (T1) model were co-registered to a common coordinate system. Mesh displacement and contour discrepancy were measured. Bone regeneration was evaluated in terms of bone volume and implant-related bone height and width. Classification, time, and rate of mesh exposures were recorded.RESULTSTi-mesh exhibited 0.57 ± 0.65 mm buccal displacement from T1 to T2 and 0.58 ± 0.57 mm apical displacement from T2 to T3. Mesh contour discrepancy was 0.70 ± 0.20 mm between T1 and T2 and decreased to 0.37 ± 0.12 mm between T2 and T3. Comparing T2 to T1, graft volume accuracy reached 91.1% ± 7.6%. Non-infected mesh exposure occurred in 26% implant sites. From T2 to T3, vertical bone resorption of 1.69 ± 1.56 mm and 0.14 ± 0.63 mm were recorded in exposed and non-exposed groups, respectively.CONCLUSIONSTo our knowledge, this is the first study to validate the use of a vacuum-formed template for positioning 3DPC Ti-mesh. Within the study limitations, this technique is a feasible approach for placing customized mesh in anterior maxillary GBR.
{"title":"Placement Error and Bone Regeneration of Customized Titanium Mesh With Vacuum-Formed Placing Template for Anterior Maxillary Bone Defects: A Retrospective Case Series Study.","authors":"Shunhao Zhang,Mi Zhou,Yuxuan Zhao,Wen Chen,Xiaoxiao Cai","doi":"10.1111/clr.70115","DOIUrl":"https://doi.org/10.1111/clr.70115","url":null,"abstract":"OBJECTIVESTo evaluate placement error, bone regeneration, and mesh exposure of three-dimensionally printed customized titanium mesh (3DPC Ti-mesh) guided by a vacuum-formed placing template in guided bone regeneration (GBR) for anterior maxillary defects.MATERIAL AND METHODS10 patients (23 implants) with Terheyden 2/4 or 3/4 defects were included. CBCT data of pre-operation (T0), immediate post-operation (T2), and 5-8 months post-operation (T3) were reconstructed. These three models and preoperative design (T1) model were co-registered to a common coordinate system. Mesh displacement and contour discrepancy were measured. Bone regeneration was evaluated in terms of bone volume and implant-related bone height and width. Classification, time, and rate of mesh exposures were recorded.RESULTSTi-mesh exhibited 0.57 ± 0.65 mm buccal displacement from T1 to T2 and 0.58 ± 0.57 mm apical displacement from T2 to T3. Mesh contour discrepancy was 0.70 ± 0.20 mm between T1 and T2 and decreased to 0.37 ± 0.12 mm between T2 and T3. Comparing T2 to T1, graft volume accuracy reached 91.1% ± 7.6%. Non-infected mesh exposure occurred in 26% implant sites. From T2 to T3, vertical bone resorption of 1.69 ± 1.56 mm and 0.14 ± 0.63 mm were recorded in exposed and non-exposed groups, respectively.CONCLUSIONSTo our knowledge, this is the first study to validate the use of a vacuum-formed template for positioning 3DPC Ti-mesh. Within the study limitations, this technique is a feasible approach for placing customized mesh in anterior maxillary GBR.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"16 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147447019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Weinreuter,Kevin Richter,Thomas Stober,Peter Rammelsberg,Stefanie Kappel
OBJECTIVETo evaluate the frequency and quantity of residual cement after cementation of monolithic zirconia crowns with glass ionomer or resin composite cement on customized ceramic abutments, following different intraoral retention times. The influence of margin location, quadrant and implant region was also assessed.MATERIALS AND METHODS40 patients received cemented monolithic single crowns on customized ceramic abutments of bone-level implants. They were randomly assigned to four groups: GC0 (glass ionomer, immediate removal), GC4 (glass ionomer, 4 weeks), RC0 (resin composite, immediate), and RC4 (resin composite, 4 weeks). Each crown was fabricated with an occlusal access opening to enable abutment-crown removal. Cementation and excess removal were performed by one experienced clinician. After the specified time, suprastructures were unscrewed and examined for residual cement. Image analysis (GIMP) calculated the ratio of cement-covered to total abutment and peri-implant tissue surface.RESULTSResidual cement was detected on 39/40 abutments (97.5%), affecting 137/160 surfaces (85.6%). Median ratios were 0.020 (Q1 0.015, Q3 0.033) in GC0, 0.042 (0.014, 0.087) in GC4, 0.078 (0.054, 0.114) in RC0, and 0.130 (0.074, 0.195) in RC4. Resin cement left significantly more residues than glass ionomer (p < 0.001). Trends were also observed for margin location and implant region. Radiographs were insufficient to detect interproximal cement.CONCLUSIONSBoth cements left detectable residues. Resin cement produced significantly larger areas, while retention time did not reduce cement quantity. Glass ionomer appears preferable for implant-supported single crowns.TRIAL REGISTRATIONGerman Clinical Trials Register (DRKS00004158; DRKS00011743).
{"title":"Residual Cement Excess of Composite Versus Glass Ionomer Cement in Implant-Supported Single Crowns After Different Intraoral Exposure Times-A Randomized Controlled Clinical Trial.","authors":"Maria Weinreuter,Kevin Richter,Thomas Stober,Peter Rammelsberg,Stefanie Kappel","doi":"10.1111/clr.70113","DOIUrl":"https://doi.org/10.1111/clr.70113","url":null,"abstract":"OBJECTIVETo evaluate the frequency and quantity of residual cement after cementation of monolithic zirconia crowns with glass ionomer or resin composite cement on customized ceramic abutments, following different intraoral retention times. The influence of margin location, quadrant and implant region was also assessed.MATERIALS AND METHODS40 patients received cemented monolithic single crowns on customized ceramic abutments of bone-level implants. They were randomly assigned to four groups: GC0 (glass ionomer, immediate removal), GC4 (glass ionomer, 4 weeks), RC0 (resin composite, immediate), and RC4 (resin composite, 4 weeks). Each crown was fabricated with an occlusal access opening to enable abutment-crown removal. Cementation and excess removal were performed by one experienced clinician. After the specified time, suprastructures were unscrewed and examined for residual cement. Image analysis (GIMP) calculated the ratio of cement-covered to total abutment and peri-implant tissue surface.RESULTSResidual cement was detected on 39/40 abutments (97.5%), affecting 137/160 surfaces (85.6%). Median ratios were 0.020 (Q1 0.015, Q3 0.033) in GC0, 0.042 (0.014, 0.087) in GC4, 0.078 (0.054, 0.114) in RC0, and 0.130 (0.074, 0.195) in RC4. Resin cement left significantly more residues than glass ionomer (p < 0.001). Trends were also observed for margin location and implant region. Radiographs were insufficient to detect interproximal cement.CONCLUSIONSBoth cements left detectable residues. Resin cement produced significantly larger areas, while retention time did not reduce cement quantity. Glass ionomer appears preferable for implant-supported single crowns.TRIAL REGISTRATIONGerman Clinical Trials Register (DRKS00004158; DRKS00011743).","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"22 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OBJECTIVESThis systematic review aimed to investigate the effect of tobacco smoking and smoke-free products as risk factors for dental implants.MATERIALS AND METHODSThree databases were searched to identify studies reporting on the risk of implant failure/survival in tobacco smokers or smoke-free users as compared to non-smokers in studies with ≥ 1 year of follow-up post-implant loading. Data on biological complications and radiographic peri-implant crestal bone loss (CBL) were also collected. Meta-analyses computed the Odds Ratio (OR) of implant survival with its confidence interval by applying the DerSimonian and Laird's random effect method, with p set at < 0.01.RESULTSForty-five articles reporting on 44 studies were included, 41 of which reported on the effect of cigarette smoking, with a follow-up from 1 to up to 17 years. Overall, a significantly reduced implant survival both at implant and patient level was indicated in cigarette smokers (OR = 0.40, 95% CI 0.27; 0.61, p < 0.001 and OR = 0.43, 95% CI 0.20; 0.90, p = 0.02, respectively). An increased CBL of 0.64 mm (95% CI 0.29; 0.99, p < 0.001) was also suggested in cigarette smokers, and the majority of studies reported a higher incidence of peri-implantitis. Insufficient data are available for smoke-free users.CONCLUSIONSAlthough tobacco smoking is not considered an absolute contraindication for implant therapy, evidence indicates that it has a detrimental effect on peri-implant tissues, leading to an increased risk of implant failure and crestal bone loss. Individual behavioural counselling for smoking cessation should always be integrated in the treatment plan of patients receiving implant-supported rehabilitations.TRIAL REGISTRATIONPROSPERO number: CRD42024628116.
目的本系统综述旨在探讨吸烟和无烟产品作为种植体危险因素的影响。材料和方法检索了三个数据库,以确定在植入后随访≥1年的研究中,吸烟者或无烟使用者与非吸烟者相比,报告了种植体失败/生存风险的研究。生物学并发症和种植体周围嵴骨丢失(CBL)的影像学数据也被收集。meta分析采用DerSimonian和Laird随机效应法计算种植体存活的优势比(Odds Ratio, OR)及其置信区间,p < 0.01。结果纳入了44项研究的45篇文章,其中41篇报道了吸烟的影响,随访时间从1年到17年不等。总体而言,吸烟者在种植体和患者水平上的种植体存活率均显著降低(OR = 0.40, 95% CI 0.27; 0.61, p < 0.001; OR = 0.43, 95% CI 0.20; 0.90, p = 0.02)。吸烟者的CBL增加了0.64 mm (95% CI 0.29; 0.99, p < 0.001),大多数研究报告了种植体周围炎的发生率较高。无烟使用者的数据不足。结论虽然吸烟不是种植体治疗的绝对禁忌症,但有证据表明吸烟对种植体周围组织有不利影响,导致种植体失败和牙冠骨丢失的风险增加。个人戒烟行为咨询应始终纳入患者接受种植支持康复的治疗计划。试验注册号:CRD42024628116。
{"title":"Tobacco Smoking and Smoke-Free Products as Risk Factors for Dental Implants: A Systematic Review.","authors":"Calciolari Elena,Corbella Stefano,Dourou Marina,Ercal Pinar,Donos Nikolaos","doi":"10.1111/clr.70108","DOIUrl":"https://doi.org/10.1111/clr.70108","url":null,"abstract":"OBJECTIVESThis systematic review aimed to investigate the effect of tobacco smoking and smoke-free products as risk factors for dental implants.MATERIALS AND METHODSThree databases were searched to identify studies reporting on the risk of implant failure/survival in tobacco smokers or smoke-free users as compared to non-smokers in studies with ≥ 1 year of follow-up post-implant loading. Data on biological complications and radiographic peri-implant crestal bone loss (CBL) were also collected. Meta-analyses computed the Odds Ratio (OR) of implant survival with its confidence interval by applying the DerSimonian and Laird's random effect method, with p set at < 0.01.RESULTSForty-five articles reporting on 44 studies were included, 41 of which reported on the effect of cigarette smoking, with a follow-up from 1 to up to 17 years. Overall, a significantly reduced implant survival both at implant and patient level was indicated in cigarette smokers (OR = 0.40, 95% CI 0.27; 0.61, p < 0.001 and OR = 0.43, 95% CI 0.20; 0.90, p = 0.02, respectively). An increased CBL of 0.64 mm (95% CI 0.29; 0.99, p < 0.001) was also suggested in cigarette smokers, and the majority of studies reported a higher incidence of peri-implantitis. Insufficient data are available for smoke-free users.CONCLUSIONSAlthough tobacco smoking is not considered an absolute contraindication for implant therapy, evidence indicates that it has a detrimental effect on peri-implant tissues, leading to an increased risk of implant failure and crestal bone loss. Individual behavioural counselling for smoking cessation should always be integrated in the treatment plan of patients receiving implant-supported rehabilitations.TRIAL REGISTRATIONPROSPERO number: CRD42024628116.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"1 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147346399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vincenzo Iorio-Siciliano, Andrea Blasi, Leopoldo Mauriello, Peter Windisch, Giovanni E Salvi, Anton Sculean, Luca Ramaglia
Objectives: To evaluate the effects of submarginal instrumentation (SI) with or without adjunctive delivery of sodium hypochlorite (NaOCl)/amino acids and cross-linked hyaluronic acid (xHyA) gel in the treatment of peri-implant mucositis (PM).
Material and methods: Forty implants supporting single-unit crowns diagnosed with PM in 40 patients were randomly assigned to test (SI + NaOCl/amino acids and xHyA) or control group (SI alone). The primary outcome was mean BoP change. Full-Mouth Plaque Score (FMPS), Full-Mouth Bleeding Score (FMBS), modified plaque index (mPlI), and probing depth (PD) were assessed as secondary outcomes. Clinical parameters were assessed at baseline, 3 and 6 months. Disease resolution was also recorded.
Results: Two patients were lost during follow-up while 38 patients completed the study without adverse effects. After 6 months, all clinical parameters improved statistically significantly in both groups (p < 0.05). The change in mean BoP at 1, 3, and 6 months was 72.2% ± 24.3%, 70.4% ± 24.3%, and 63.0% ± 24.6% for test group and 70.0% ± 19.9%, 66.7% ± 24.8%, and 56.7% ± 30.8% for control group. The mean BoP change in experimental procedure was statistically significant at all investigation time points (p < 0.05). Regarding disease resolution, implants with initial PD ≤ 4 mm did not show differences among groups (p > 0.05); conversely, an initial PD = 5 mm yielded a statistically significant difference (p < 0.05). Disease resolution correlation with test group was statistically significant with a 3.77 odds ratio.
Conclusion: Within the limitations of the present study, adjunctive delivery of NaOCl/amino acids and xHyA to SI yielded superior clinical outcomes compared with SI alone in the treatment of PM.
{"title":"Non-Surgical Submarginal Instrumentation of Peri-Implant Mucositis With Delivery of Sodium Hypochlorite/Amino Acids and Cross-Linked Hyaluronic Acid: A Randomized Clinical Trial.","authors":"Vincenzo Iorio-Siciliano, Andrea Blasi, Leopoldo Mauriello, Peter Windisch, Giovanni E Salvi, Anton Sculean, Luca Ramaglia","doi":"10.1111/clr.70109","DOIUrl":"https://doi.org/10.1111/clr.70109","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effects of submarginal instrumentation (SI) with or without adjunctive delivery of sodium hypochlorite (NaOCl)/amino acids and cross-linked hyaluronic acid (xHyA) gel in the treatment of peri-implant mucositis (PM).</p><p><strong>Material and methods: </strong>Forty implants supporting single-unit crowns diagnosed with PM in 40 patients were randomly assigned to test (SI + NaOCl/amino acids and xHyA) or control group (SI alone). The primary outcome was mean BoP change. Full-Mouth Plaque Score (FMPS), Full-Mouth Bleeding Score (FMBS), modified plaque index (mPlI), and probing depth (PD) were assessed as secondary outcomes. Clinical parameters were assessed at baseline, 3 and 6 months. Disease resolution was also recorded.</p><p><strong>Results: </strong>Two patients were lost during follow-up while 38 patients completed the study without adverse effects. After 6 months, all clinical parameters improved statistically significantly in both groups (p < 0.05). The change in mean BoP at 1, 3, and 6 months was 72.2% ± 24.3%, 70.4% ± 24.3%, and 63.0% ± 24.6% for test group and 70.0% ± 19.9%, 66.7% ± 24.8%, and 56.7% ± 30.8% for control group. The mean BoP change in experimental procedure was statistically significant at all investigation time points (p < 0.05). Regarding disease resolution, implants with initial PD ≤ 4 mm did not show differences among groups (p > 0.05); conversely, an initial PD = 5 mm yielded a statistically significant difference (p < 0.05). Disease resolution correlation with test group was statistically significant with a 3.77 odds ratio.</p><p><strong>Conclusion: </strong>Within the limitations of the present study, adjunctive delivery of NaOCl/amino acids and xHyA to SI yielded superior clinical outcomes compared with SI alone in the treatment of PM.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov: NCT05926297.</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147316619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}