Complementary therapies in medicine最新文献_第5页

Effects of qigong for physical and psychological well-being in pregnancy: A multicenter randomized controlled trial 气功对妊娠期身心健康的影响：一项多中心随机对照试验。

IF 3.5 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine

Pub Date : 2025-10-30 DOI: 10.1016/j.ctim.2025.103284

Emine Dundar Ahi , Ozlem Kuculmez , Sevgi Ikbali Afsar , Rahsan Eyup Dogan

Background

Psychological stress and anxiety during pregnancy can adversely affect both maternal and fetal health. Qigong, a traditional Chinese mind–body exercise, is believed to promote physical and mental well-being during pregnancy. This study aimed to investigate the effects of qigong on anxiety, stress, and exercise self-efficacy in pregnant women.

Methods

This multicenter randomized controlled clinical trial included pregnant women in their second trimester attending prenatal education classes at Baskent University and Alaaddin Keykubat University. Women in the first or third trimester with uncontrolled systemic diseases, high-risk pregnancies, or irregular attendance were excluded. Participants were randomly assigned via Randomizer.org to either the Qigong group or the control group. The Qigong group performed Baduanjin qigong exercises for 30–45 min, three times a week, while the control group received standard prenatal counseling. Demographic data were recorded. All participants completed the Pregnancy-Related Anxiety Scale (PrAS), Pregnancy Stress Rating Scale (PSRS), and Pregnancy Exercise Self-Efficacy Scale (P-ESES).

Results

A total of 102 pregnant women were analyzed (qigong group: 52; control group: 50). The mean age was 27.95 ± 3.66 years, and the mean gestational week was 26.94 ± 2.12. The qigong group showed significantly lower systolic and diastolic blood pressure increases compared to the control group (p < 0.05). Exercise self-efficacy scores increased significantly in the qigong group (p < 0.05). Pregnancy-related anxiety and stress scores, including all subscales, showed significant improvement in the qigong group (p < 0.05), with no significant changes in the control group (p > 0.05).

Conclusions

Baduanjin qigong was effective in reducing anxiety and stress levels and improving exercise self-efficacy in pregnant women. This non-pharmacological intervention may offer a safe, supportive approach to mental well-being during pregnancy.

背景：怀孕期间的心理压力和焦虑会对母亲和胎儿的健康产生不利影响。气功，一种传统的中国身心锻炼，被认为可以促进怀孕期间的身心健康。本研究旨在探讨气功对孕妇焦虑、压力及运动自我效能的影响。方法：本多中心随机对照临床试验纳入了在Baskent大学和Alaaddin Keykubat大学参加产前教育班的妊娠中期孕妇。在妊娠早期或晚期有未控制的全身性疾病、高危妊娠或不规则分娩的妇女被排除在外。参与者通过Randomizer.org被随机分配到气功组和对照组。气功组每周进行三次八段锦气功，每次30-45分钟，而对照组接受标准的产前咨询。记录人口统计数据。所有参与者均完成了妊娠相关焦虑量表（PrAS）、妊娠压力评定量表（PSRS）和妊娠运动自我效能量表（P-ESES）。结果：共分析102例孕妇（气功组52例，对照组50例）。平均年龄27.95±3.66岁，平均妊娠周26.94±2.12周。与对照组相比，气功组的收缩压和舒张压升高明显降低（p < 0.05）。气功组运动自我效能感评分显著升高（p < 0.05）。气功组妊娠相关焦虑和压力评分（包括所有分量表）均有显著改善（p < 0.05），对照组无显著变化（p < 0.05）。结论：八段锦气功能有效降低孕妇焦虑、应激水平，提高运动自我效能感。这种非药物干预可能为怀孕期间的心理健康提供一种安全、支持性的方法。

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引用次数: 0

Corrigendum to “AI-assisted drawing therapy for children with ADHD: A randomised controlled trial” [Complement Ther Med 94 (2025) 103262] “人工智能辅助绘画治疗多动症儿童：一项随机对照试验”的勘误表[补体医学94(2025)103262]。

IF 3.5 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine

Pub Date : 2025-10-30 DOI: 10.1016/j.ctim.2025.103277

Jing Xu , Runqing Lin , Aijia Zhang , Qiang Chen , Dexin Li , Jiajie Chen , Minglu Song , Shumei Chen , Bingjiao Yang , Linyang Li , Haotian Xu , Jinlin Peng , Yanrong Tang , Wenhua Yang , Xuexing Luo , Xiang Zhou , Jue Wang , Guanghui Huang

引用次数: 0

Classical beats and white noise: Unveiling the effect of different music characteristics on heart rate variability 古典节拍与白噪音：揭示不同音乐特征对心率变异性的影响。

IF 3.5 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine

Pub Date : 2025-10-30 DOI: 10.1016/j.ctim.2025.103288

Shari Pepplinkhuizen , Nicole J. van Steijn , E. Madelief J. Marsman , Sanne ten Berg , Lucas M. de Haas , Pieter S. Kleer , I. Tarik Küçük , Kay Lamerigts , Astrid C. van Nieuwkerk , Jolien A. de Veld , Jos W.R. Twisk , Puck J. Peltenburg , Tinka J. van Trier , Michiel M. Winter

Aims

Low heart rate variability (HRV) is associated with increased morbidity and mortality in various health conditions. Music can enhance HRV, but it remains unclear which music characteristics are most effective. This study aimed to assess the impact of music genre, white noise, tempo, and personal music preferences on HRV.

Methods

In this single-blind, randomised, within-subject study, participants without atrial fibrillation or pacemaker dependency listened to three-minute fragments of white noise and four music genres (classical, rock, electronic and a personal music) in random order. Participants were randomised to a slow or fast tempo group. Heart beats were recorded using a smartwatch containing a photoplethysmography (PPG) sensor; non-sinus beats were excluded using a custom algorithm. HRV was analysed using a general linear mixed model adjusted for heart rate, sex, age and tempo, with interaction analysis for tempo effects.

Results

A total of 242 participants were included. White noise was associated with the highest HRV across all tested metrics: standard deviation of normal-to-normal intervals (SDNN), root mean square of successive differences (RMSSD), low-frequency power (LF), and high-frequency power (HF). Furthermore, HRV (RMSSD) was higher during classical music compared to electronic and personal music (P = 0.025 and P = 0.030). Interaction analysis showed the latter was due to differences only in slow music tempo.

Conclusion

Slow, classical music enhances HRV more than electronic or personal music, suggesting its therapeutic potential. Remarkably, white noise showed the greatest increase in HRV compared to all music genres, possibly due to its consistent and monotonous sound characteristics inducing a relaxation response and increased parasympathetic activity.

目的：在各种健康状况下，低心率变异性（HRV）与发病率和死亡率增加有关。音乐可以提高心率，但目前尚不清楚哪种音乐特征最有效。本研究旨在评估音乐类型、白噪音、节奏和个人音乐偏好对HRV的影响。方法：在这项单盲、随机、受试者内的研究中，没有心房颤动或心脏起搏器依赖的参与者按随机顺序听三分钟的白噪音片段和四种音乐类型（古典、摇滚、电子和个人音乐）。参与者被随机分为慢节奏组和快节奏组。使用包含光电容积脉搏波描记（PPG）传感器的智能手表记录心跳；使用自定义算法排除非窦性心跳。采用一般线性混合模型对心率、性别、年龄和节奏进行调整，并对节奏效应进行交互分析，分析HRV。结果：共纳入242名受试者。在所有测试指标中，白噪声与最高HRV相关：正态间隔的标准差（SDNN）、连续差的均方根（RMSSD）、低频功率（LF）和高频功率（HF）。此外，古典音乐的HRV （RMSSD）高于电子音乐和个人音乐（P=0.025和P=0.030）。相互作用分析表明，后者仅是由于慢音乐节奏的差异。结论：慢速古典音乐比电子音乐或个人音乐更能提高HRV，显示其治疗潜力。值得注意的是，与所有音乐类型相比，白噪音显示出最大的HRV增长，可能是由于其一贯和单调的声音特征诱导放松反应和增加副交感神经活动。

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引用次数: 0

Yoga-based breathing and relaxation as adjunctive therapy for chronic migraine: A randomized controlled trial on clinical outcomes and autonomic regulation 以瑜伽为基础的呼吸和放松作为慢性偏头痛的辅助治疗：临床结果和自主调节的随机对照试验。

IF 3.5 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine

Pub Date : 2025-10-30 DOI: 10.1016/j.ctim.2025.103291

M.U. Sujan , Ganagarajan Inbaraj , Rao Mohan Raghavendra , H.S. Vadiraja , Jahnavi V. Madhu , Shilpa Mulakur , Ravikiran Kisan , Meghana Adoor , M.S. Raghuram , Babina Nandakumar , Atchayaram Nalini , Talakad N Sathyaprabha

Background

Chronic migraine is a disabling neurological condition often associated with autonomic dysregulation. Yoga-based interventions, particularly pranayama and relaxation, may provide non-pharmacological benefits; however, few studies have systematically evaluated their physiological and clinical impact.

Objective

To assess the adjunctive effects of a structured pranayama and relaxation (P + R) program on clinical outcomes and autonomic function in patients with chronic migraine receiving standard medical treatment.

Methods

In this randomized controlled trial, 90 adults with chronic migraine were assigned to either a P + R intervention or a control group. The P + R group received daily guided sessions for 12 weeks alongside standard pharmacological care, while the control group continued standard care alone. The primary outcome was change in monthly headache frequency. Secondary outcomes included headache intensity (VAS), migraine-related disability (HIT-6), quality of life (SF-36), and autonomic function assessed through heart rate variability and standardized autonomic tests. Assessments were conducted at baseline and after 12 weeks.

Results

Both groups exhibited significant clinical improvement following the intervention period. However, the intervention group demonstrated a significantly greater reduction in headache frequency (mean reduction – 7.1 vs – 4.6 days/month, p < 0.001), pain intensity (∆VAS – 6.8 vs – 3.2, p < 0.001), and disability scores (∆HIT-6 – 33.0 vs –21.6, p < 0.001) compared to the control group. Quality of life improvements were more pronounced in the intervention arm, especially in physical and vitality domains. Objective autonomic assessment revealed increased HRV indices (higher RMSSD, HF_nu; lower LF/HF ratio) and significant reductions in resting heart rate and blood pressure only in the intervention group, indicating enhanced parasympathetic tone. No adverse events were reported, and adherence rates were high.

Conclusion

A 12-week pranayama and relaxation program, when added to standard migraine therapy, resulted in significant clinical and autonomic improvements. These findings support the integration of mind-body techniques as effective adjuncts in the multidisciplinary management of chronic migraine.

背景：慢性偏头痛是一种致残的神经系统疾病，通常与自主神经失调有关。以瑜伽为基础的干预，特别是调息和放松，可能提供非药物的益处；然而，很少有研究系统地评估其生理和临床影响。目的：评估结构化调息和放松（P+R）方案对接受标准药物治疗的慢性偏头痛患者的临床结局和自主神经功能的辅助作用。方法：在这项随机对照试验中，90名患有慢性偏头痛的成年人被分配到P+R干预组或对照组。P+R组接受每日指导课程，为期12周，同时接受标准药物治疗，而对照组继续单独接受标准治疗。主要结局是每月头痛频率的变化。次要结局包括头痛强度（VAS）、偏头痛相关残疾（HIT-6）、生活质量（SF-36）以及通过心率变异性和标准化自主神经测试评估的自主神经功能。在基线和12周后进行评估。结果：两组患者在干预期后均有明显的临床改善。然而，干预组显示头痛频率明显减少（平均减少-7.1天/月vs -4.6天/月）。结论：12周调息和放松计划，当添加到标准偏头痛治疗时，导致显着的临床和自主神经改善。这些发现支持身心技术作为慢性偏头痛多学科治疗的有效辅助手段的整合。

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引用次数: 0

Effects of Baduanjin on exercise tolerance, cardiac function, and quality of life in patients with heart failure: A systematic review and meta-analysis 八段金对心力衰竭患者运动耐量、心功能和生活质量的影响：一项系统综述和荟萃分析

IF 3.5 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine

Pub Date : 2025-10-30 DOI: 10.1016/j.ctim.2025.103280

Wujiao Wang , Jia Qi , Jie Wan , Zhao Lin , Peng Yang , Hongyue Ge , Peifen Chang , Tianli Li

Objective

Heart failure (HF) remains a significant health burden around the world, and Baduanjin is an effective intervention for patients with HF. This study aimed to objectively evaluate the effects of Baduanjin on exercise tolerance, cardiac function, and quality of life in patients with HF.

Method

From the time the database was constructed to May 8, 2025, we searched eight databases and two registry systems. Clinical randomized controlled trials (RCTs) of Baduanjin in treating HF were retrieved. The primary outcomes were the 6-minute walk test (6MWT) and left ventricular ejection fraction (LVEF). Secondary outcomes were left ventricular end-diastolic dimension (LVDD), left ventricular end-systolic dimension (LVSD), N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP), BNP levels, Minnesota Living with Heart Failure Questionnaire (MLHFQ), Anaerobic threshold (AT), Metabolic equivalent of task (MET), peak oxygen consumption (VO₂ peak), and Maximal oxygen consumption (VO₂ max). Two researchers performed rigorous data extraction and quality assessment. The quality of the included RCTs was evaluated using the Cochrane Risk of Bias assessment tool, version 2.0 (RoB 2), and statistical analyses were performed using RevMan 5.4 and Stata 17.0 software.

Result

A total of 46 RCTs involving 3597 people were included in this study. Meta-analysis showed that Baduanjin could improve the 6MWT [ MD= 50.71, 95 % CI (37.48, 63.94), P < 0.01], LVEF [ MD= 3.57, 95 % CI (2.70, 4.45), P < 0.01], LVDD [ MD = -2.33, 95 % CI (-2.82, −1.84), P < 0.01], LVSD [ MD = -1.83, 95 % CI (-2.31, −1.36), P < 0.01], NT-proBNP levels [ MD = -139.49, 95 % CI (-204.08, −74.89), P < 0.01], BNP levels [ MD = -77.68, 95 % CI (-110.80, −44.56), P < 0.01], MLHFQ [ MD = -8.15, 95 % CI (-12.31, −3.99), P < 0.01], MLHFQ-E [ MD = -3.23, 95 % CI (-3.71, −2.74), P < 0.01], MLHFQ-P [ MD = -3.23, 95 % CI (-4.17, −3.29), P < 0.01], MLHFQ-G [ MD = -3.56, 95 % CI (-4.76, −2.35), P < 0.01], AT [ MD= 1.65, 95 % CI (1.22, 2.09), P < 0.01], MET [ MD= 0.65, 95 % CI (0.12, 1.19), P ＜0.05], VO₂ peak [ MD= 1.36, 95 % CI (0.40, 2.31), P ＜0.01], and VO₂ max [ MD= 2.21, 95 % CI (1.05, 3.37), P < 0.01] when compared to control groups, and the subgroup analyses showed that the efficacy of 3 months of continuous intervention with Baduanjin was the best.

Conclusion

Our study is the first comprehensive meta-analysis to evaluate the treatment of HF with Baduanjin. The results suggest that Baduanjin improves exercise tolerance, cardiac function, and quality of life in patients with HF.

目的：心衰（HF）在世界范围内仍然是一个重要的健康负担，八段金是一种有效的心力衰竭患者干预措施。本研究旨在客观评价八段金对心衰患者运动耐量、心功能及生活质量的影响。方法：从数据库建立时间到2025年5月8日，检索8个数据库和2个注册系统。回顾性分析八段金治疗心衰的临床随机对照试验。主要结果为6分钟步行测试（6MWT）和左心室射血分数（LVEF）。次要结果为左室舒张末期尺寸（LVDD）、左室收缩末期尺寸（LVSD）、n -末端前脑利钠肽（NT-proBNP）、BNP水平、明尼苏达心力衰竭患者问卷（MLHFQ）、无氧阈值（AT）、任务代谢当量（MET）、峰值耗氧量（VO2峰值）和最大耗氧量（VO2 max）。两名研究人员进行了严格的数据提取和质量评估。采用Cochrane 2.0版偏倚风险评估工具（RoB 2）对纳入的rct进行质量评价，采用RevMan 5.4和Stata 17.0软件进行统计分析。结果：本研究共纳入46项rct，涉及3597人。meta分析显示，与对照组相比，八段锦可改善6MWT [MD=50.71, 95% CI(37.48, 63.94)]、P2峰[MD= 1.36, 95% CI (0.40, 2.31), P <0.01]、VO2 max [MD= 2.21, 95% CI (1.05, 3.37), P <0.01]，亚组分析显示，连续干预3个月疗效最佳。结论：本研究是首个评价八段金治疗心衰的综合meta分析。结果提示八段金可改善心衰患者的运动耐量、心功能和生活质量。

{"title":"Effects of Baduanjin on exercise tolerance, cardiac function, and quality of life in patients with heart failure: A systematic review and meta-analysis","authors":"Wujiao Wang , Jia Qi , Jie Wan , Zhao Lin , Peng Yang , Hongyue Ge , Peifen Chang , Tianli Li","doi":"10.1016/j.ctim.2025.103280","DOIUrl":"10.1016/j.ctim.2025.103280","url":null,"abstract":"<div><h3>Objective</h3><div>Heart failure (HF) remains a significant health burden around the world, and Baduanjin is an effective intervention for patients with HF. This study aimed to objectively evaluate the effects of Baduanjin on exercise tolerance, cardiac function, and quality of life in patients with HF.</div></div><div><h3>Method</h3><div>From the time the database was constructed to May 8, 2025, we searched eight databases and two registry systems. Clinical randomized controlled trials (RCTs) of Baduanjin in treating HF were retrieved. The primary outcomes were the 6-minute walk test (6MWT) and left ventricular ejection fraction (LVEF). Secondary outcomes were left ventricular end-diastolic dimension (LVDD), left ventricular end-systolic dimension (LVSD), N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP), BNP levels, Minnesota Living with Heart Failure Questionnaire (MLHFQ), Anaerobic threshold (AT), Metabolic equivalent of task (MET), peak oxygen consumption (VO<sub>2</sub> peak), and Maximal oxygen consumption (VO<sub>2</sub> max). Two researchers performed rigorous data extraction and quality assessment. The quality of the included RCTs was evaluated using the Cochrane Risk of Bias assessment tool, version 2.0 (RoB 2), and statistical analyses were performed using RevMan 5.4 and Stata 17.0 software.</div></div><div><h3>Result</h3><div>A total of 46 RCTs involving 3597 people were included in this study. Meta-analysis showed that Baduanjin could improve the 6MWT [ MD= 50.71, 95 % CI (37.48, 63.94), <em>P</em> < 0.01], LVEF [ MD= 3.57, 95 % CI (2.70, 4.45), <em>P</em> < 0.01], LVDD [ MD = -2.33, 95 % CI (-2.82, −1.84), <em>P</em> < 0.01], LVSD [ MD = -1.83, 95 % CI (-2.31, −1.36), <em>P</em> < 0.01], NT-proBNP levels [ MD = -139.49, 95 % CI (-204.08, −74.89), <em>P</em> < 0.01], BNP levels [ MD = -77.68, 95 % CI (-110.80, −44.56), <em>P</em> < 0.01], MLHFQ [ MD = -8.15, 95 % CI (-12.31, −3.99), <em>P</em> < 0.01], MLHFQ-E [ MD = -3.23, 95 % CI (-3.71, −2.74), <em>P</em> < 0.01], MLHFQ-P [ MD = -3.23, 95 % CI (-4.17, −3.29), <em>P</em> < 0.01], MLHFQ-G [ MD = -3.56, 95 % CI (-4.76, −2.35), <em>P</em> < 0.01], AT [ MD= 1.65, 95 % CI (1.22, 2.09), <em>P</em> < 0.01], MET [ MD= 0.65, 95 % CI (0.12, 1.19), <em>P</em> ＜0.05], VO<sub>2</sub> peak [ MD= 1.36, 95 % CI (0.40, 2.31), <em>P</em> ＜0.01], and VO<sub>2</sub> max [ MD= 2.21, 95 % CI (1.05, 3.37), <em>P</em> < 0.01] when compared to control groups, and the subgroup analyses showed that the efficacy of 3 months of continuous intervention with Baduanjin was the best.</div></div><div><h3>Conclusion</h3><div>Our study is the first comprehensive meta-analysis to evaluate the treatment of HF with Baduanjin. The results suggest that Baduanjin improves exercise tolerance, cardiac function, and quality of life in patients with HF.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103280"},"PeriodicalIF":3.5,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of yoga as mind-body exercise in fibromyalgia management: A systematic review 瑜伽作为身心运动在纤维肌痛治疗中的作用：系统综述

IF 3.5 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine

Pub Date : 2025-10-30 DOI: 10.1016/j.ctim.2025.103290

Ebru Durusoy , Edibe Ünal

Background

Fibromyalgia is a syndrome linked to chronic pain and biopsychosocial problems, with management limited by unclear etiology and treatments. Yoga is a mind-body practice combining movement, breathing, meditation, and coping skills that may address treatment needs. However, evidence is limited. This study aims to evaluate the effect of yoga on fibromyalgia symptoms and assess the quality of existing studies.

Methods

Randomised controlled trials (RCTs) published since 2005 that examined yoga practice in adults with Fibromyalgia were searched in March 2025 in the Google Scholar, PubMed, Scopus, Web of Science, ScienceDirect, PEDro, and Cochrane Library databases. The PEDro scale was used to assess methodological quality.

Results

Three RCTs (reported in four publications) with 116 female participants (aged 18–60) were included. All studies reported significant improvements in Fibromyalgia Impact Questionnaire (FIQ)/Revised Fibromyalgia Impact Questionnaire (FIQR) scores in favor of yoga, with three also indicating reduced pain. Studies evaluating psychosocial parameters and FIQ/FIQR subgroup analyses have shown significant and clinically important improvements in fatigue, depression, anxiety, strength, and coping strategies. Follow-up data showed that gains were largely maintained, with positive changes observed in physical strength, perception of improvement, acceptance level, and coping strategies. Studies’ quality score average was 6.5 (Good).

Conclusion

Results suggest that yoga may improve FIQ/FIQR scores, pain, fatigue, depression, anxiety, muscle strength, and coping strategies. These results point to the possibility that yoga may be an effective complementary intervention option for alleviating fibromyalgia symptoms and improving psychological and physical well-being. High-quality research is required to strengthen generalisability.

背景纤维肌痛是一种与慢性疼痛和生物心理社会问题相关的综合征，由于病因和治疗方法不明确，其治疗受到限制。瑜伽是一种结合运动、呼吸、冥想和应对技巧的身心练习，可以解决治疗需求。然而，证据有限。本研究旨在评估瑜伽对纤维肌痛症状的影响，并评估现有研究的质量。方法于2025年3月在b谷歌Scholar、PubMed、Scopus、Web of Science、ScienceDirect、PEDro和Cochrane Library数据库中检索2005年以来发表的随机对照试验（RCTs），这些试验检查了成人纤维肌痛患者的瑜伽练习。采用PEDro量表评估方法学质量。结果纳入3项随机对照试验，共纳入116名年龄在18-60岁的女性受试者。所有的研究都报告了瑜伽对纤维肌痛影响问卷(FIQ)/修订纤维肌痛影响问卷（FIQR）得分的显著改善，其中三项也表明疼痛减轻。评估社会心理参数和FIQ/FIQR亚组分析的研究显示，在疲劳、抑郁、焦虑、力量和应对策略方面有显著和临床重要的改善。随访数据显示，这些成果在很大程度上得以保持，在体力、感知改善、接受程度和应对策略方面都有积极的变化。研究质量得分平均为6.5分（良好）。结果表明，瑜伽可以改善FIQ/FIQR评分、疼痛、疲劳、抑郁、焦虑、肌肉力量和应对策略。这些结果表明，瑜伽可能是缓解纤维肌痛症状和改善心理和身体健康的有效补充干预选择。需要高质量的研究来加强普遍性。

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引用次数: 0

Efficacy of acupuncture-based adjunctive therapies in alleviating spasticity and motor function in patients with post-stroke spasticity: A systematic review and network meta-analysis 针灸辅助治疗缓解脑卒中后痉挛患者痉挛和运动功能的疗效：系统综述和网络meta分析。

IF 3.5 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine

Pub Date : 2025-10-30 DOI: 10.1016/j.ctim.2025.103282

Xinle Wang, Kaixuan Zhang, Xingxing Lin, Ziwei Liu, Leichao Wang, Feng Zhang, Lujia Xiao, Yu Gao, Yaxuan Wen, Baoqiang Dong

<div><h3>Background</h3><div>Post-stroke spasticity (PSS) is a prominent complication that severely hinders limb function recovery and diminishes quality of life in patients with stroke. Despite the widespread use of acupuncture-based adjunctive therapies, their efficacy in reducing spasticity severity, improving limb motor function, and enhancing quality of life among stroke survivors remains contentious. Therefore, a comprehensive synthesis of current evidence through evidence-based medical methodologies is essential to elucidate their clinical value.</div></div><div><h3>Objective</h3><div>This systematic review and network meta-analysis aimed to evaluate the efficacy of acupuncture-based adjunctive therapies in alleviating spasticity and improving motor function in individuals with PSS.</div></div><div><h3>Methods</h3><div>Randomized controlled trials (RCTs) investigating acupuncture for PSS were retrieved from domestic and international databases (PubMed, Web of Science, Cochrane Library, Embase, China National Knowledge Infrastructure, WanFang Data, Chinese Scientific Journal Database, and China Biomedical Literature) from inception to March 1, 2025. The risk of bias (ROB) in the included studies was assessed using the Cochrane ROB tool. Using the frequency method, relative risk (RR) was used for binary outcomes and mean difference (MD) for continuous variables, each reported with 95 % confidence intervals (CIs). Meta-analysis was performed using Stata software (version 16.0). Probability rankings were estimated using the surface under the cumulative ranking area, and subgroup analyses were conducted to validate result consistency.</div></div><div><h3>Results</h3><div>A total of 66 RCTs involving 6180 patients evaluated 13 effective acupuncture-based interventions. Based on changes in the Modified Ashworth Scale (MAS), fire-needle acupuncture (FN) [MD = –1.34, 95 % CI (–2.17, –0.51)], meridian-sinew acupuncture (MSA) [MD = –1.19, 95 % CI (–1.84, –0.55)], and manual acupuncture (MA) combined with rehabilitation therapy (RT) [MD = –0.63, 95 % CI (–0.82, –0.43)] were identified as the most effective interventions for reducing spasticity. Notably, FN also demonstrated the greatest improvements on the Clinical Spasticity Index (CSI) [MD = –7.34, 95 % CI (–9.83, –4.85)] and total effectiveness rate [RR = 2.02, 95 % CI (1.45, 2.81)]. The Fugl–Meyer Assessment (FMA) scores indicated that electroacupuncture (EA) [MD = 32.92, 95 % CI (20.83, 45.02)] yielded optimum efficacy in sensory and motor function recovery after stroke, followed by warm needle moxibustion and FN. Furthermore, subgroup analyses revealed that FN and MSA were most effective for MAS when the needle retention time was ≤ 30 min and the treatment duration was ≤ 4 weeks. In contrast, EA achieved optimal outcomes on the FMA when administered at a frequency ≥ 5 times per week, with needle retention time ≤ 30 min and treatment duration ≤ 4 weeks. Meanwhile, the SUCRA ranking results of int

背景：脑卒中后痉挛（PSS）是严重阻碍脑卒中患者肢体功能恢复和降低生活质量的重要并发症。尽管以针灸为基础的辅助疗法被广泛使用，但其在减轻痉挛严重程度、改善肢体运动功能和提高中风幸存者生活质量方面的有效性仍存在争议。因此，通过循证医学方法全面综合现有证据是阐明其临床价值的必要条件。目的：本系统综述和网络荟萃分析旨在评估针灸辅助疗法在缓解PSS患者痉挛和改善运动功能方面的疗效。方法：从PubMed、Web of Science、Cochrane Library、Embase、中国国家知识基础设施、万方数据、中国科学期刊数据库、中国生物医学文献等国内外数据库中检索自成立至2025年3月1日的研究针刺治疗PSS的随机对照试验。纳入研究的偏倚风险（ROB）采用Cochrane ROB工具进行评估。采用频率法，二元结果采用相对危险度（RR），连续变量采用平均差异（MD），每个变量均以95%置信区间（ci）报告。meta分析采用Stata软件（version 16.0）进行。利用累积排序区域下的曲面估计概率排序，并进行亚组分析以验证结果的一致性。结果：共有66项随机对照试验，涉及6180例患者，评估了13种有效的针灸干预措施。根据改良Ashworth量表（MAS）的变化，确定火针针刺（FN） [MD = -1.34, 95% CI(-2.17, -0.51)]、经络筋针（MSA） [MD = -1.19, 95% CI(-1.84, -0.55)]和手针（MA）联合康复治疗（RT） [MD = -0.63, 95% CI(-0.82, -0.43)]是缓解痉挛最有效的干预措施。值得注意的是，FN对临床痉挛指数（CSI）（MD = -7.34, 95% CI(-9.83, -4.85)）和总有效率（RR = 2.02, 95% CI(1.45, 2.81)）也有最大的改善。Fugl-Meyer评估（FMA）评分显示，电针（EA） [MD = 32.92, 95% CI(20.83, 45.02)]对脑卒中后感觉和运动功能恢复效果最佳，其次是温针和FN。亚组分析显示，FN和MSA在置针时间≤30min、治疗时间≤4周时治疗MAS最有效。相比之下，EA在FMA上达到最佳效果时，给药频率≥5次/周，留针时间≤30min，治疗时间≤4周。同时，全肢亚组干预措施的SUCRA排序结果与整体分析结果基本一致。结论：针灸辅助治疗对PSS有较好的疗效。FN和MSA相对有效，而EA最适合运动功能恢复。临床决策应以基于患者具体表现和需求的个性化治疗策略为指导。

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引用次数: 0

Effects of cultural-artistic rehabilitation activities on quality of life, anxiety and depression, and self-management level of maintenance hemodialysis: A propensity-score-matched study 文化艺术康复活动对维持性血液透析患者生活质量、焦虑、抑郁和自我管理水平的影响：一项倾向-得分匹配研究。

IF 3.5 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine

Pub Date : 2025-10-30 DOI: 10.1016/j.ctim.2025.103289

Junfan Feng , Lixia Liu , Xiaomei Chen , Baochun Guo , Jiaxiu Deng , Ru Zhou , Yanping Chen , Lijuan Lan , Hongmei Li , Yuan Zhou , Meinuan Wei , Meihong Zhuo , Xinzhou Zhang , Liping Sun

Background

Traditional mind-body therapies like Baduanjin, exercise rehabilitation, and psychological support have demonstrated clinical benefits in maintenance hemodialysis (MHD) patients. Although Baduanjin is widely acknowledged for its rehabilitative effects in chronic disease care, its combination with artistic engagement in renal disease treatment remains underexplored. Our study investigates how integrating cultural and physical interventions—targeting physical, psychological, and social health-influences quality of life (QoL), anxiety, depression, and self-management skills in MHD patients.

Methods

We conducted a survey of 109 MHD patients at our hospital’s hemodialysis center from February 2024 to March 2025. We administered several questionnaires, including the Renal Disease Quality of Life Short Form 1.3, the Self-Rating Anxiety and Depression Scale, the Chronic Disease Self-Management Questionnaire, and the Hemodialysis Patient Self-Management Scale. The cultural-artistic rehabilitation activities intervention consists of three components: The Artistic Expression Module (poetry/singing), the Modified Baduanjin-Dance Integration and the Group Narrative Therapy. These were delivered in weekly sequences of 60, 90 and 30 min. Propensity score matching, inverse probability weighting, and linear regression assessed the effects on QoL, psychological symptoms, and self-management.

Results

Following propensity score matching and inverse probability weighting adjustments, the intervention group displayed greater overall QoL scores, kidney-specific QoL improvements, and enhanced self-management abilities relative to controls (P < 0.05). A strong positive association emerged between participation in creative-physical interventions and gains in QoL, mood stabilization, and self-management proficiency.

Conclusion

In MHD patients, integrated cultural-artistic rehabilitation activities enhance quality of life, self-management competence and psychological well-being. These results encourage greater patient engagement in cultural-artistic rehabilitation activities.

背景：传统的心身疗法如八段锦、运动康复和心理支持在维持性血液透析（MHD）患者中已显示出临床疗效。虽然八段锦在慢性疾病治疗中的康复作用已得到广泛认可，但其与艺术参与在肾脏疾病治疗中的结合仍未得到充分探索。我们的研究探讨了文化和身体干预（针对身体、心理和社会健康）如何影响MHD患者的生活质量（QoL）、焦虑、抑郁和自我管理技能。方法：对2024年2月至2025年3月在我院血液透析中心就诊的109例MHD患者进行调查。我们进行了多项问卷调查，包括肾脏疾病生活质量短表1.3、焦虑和抑郁自评量表、慢性疾病自我管理问卷和血液透析患者自我管理量表。文化艺术康复活动干预包括三个组成部分：艺术表达模块（诗歌/歌唱）、改良八段锦舞整合和群体叙事治疗。这些视频按每周60分钟、90分钟和30分钟的顺序播放。倾向评分匹配、逆概率加权和线性回归评估了对生活质量、心理症状和自我管理的影响。结果：经过倾向评分匹配和逆概率加权调整后，干预组的总体生活质量评分、肾脏特异性生活质量改善和自我管理能力均高于对照组（P < 0.05）。参与创造性身体干预与生活质量、情绪稳定和自我管理熟练程度之间存在强烈的正相关。结论：综合文化艺术康复活动可提高MHD患者的生活质量、自我管理能力和心理健康水平。这些结果鼓励患者更多地参与文化艺术康复活动。

{"title":"Effects of cultural-artistic rehabilitation activities on quality of life, anxiety and depression, and self-management level of maintenance hemodialysis: A propensity-score-matched study","authors":"Junfan Feng , Lixia Liu , Xiaomei Chen , Baochun Guo , Jiaxiu Deng , Ru Zhou , Yanping Chen , Lijuan Lan , Hongmei Li , Yuan Zhou , Meinuan Wei , Meihong Zhuo , Xinzhou Zhang , Liping Sun","doi":"10.1016/j.ctim.2025.103289","DOIUrl":"10.1016/j.ctim.2025.103289","url":null,"abstract":"<div><h3>Background</h3><div>Traditional mind-body therapies like Baduanjin, exercise rehabilitation, and psychological support have demonstrated clinical benefits in maintenance hemodialysis (MHD) patients. Although Baduanjin is widely acknowledged for its rehabilitative effects in chronic disease care, its combination with artistic engagement in renal disease treatment remains underexplored. Our study investigates how integrating cultural and physical interventions—targeting physical, psychological, and social health-influences quality of life (QoL), anxiety, depression, and self-management skills in MHD patients.</div></div><div><h3>Methods</h3><div>We conducted a survey of 109 MHD patients at our hospital’s hemodialysis center from February 2024 to March 2025. We administered several questionnaires, including the Renal Disease Quality of Life Short Form 1.3, the Self-Rating Anxiety and Depression Scale, the Chronic Disease Self-Management Questionnaire, and the Hemodialysis Patient Self-Management Scale. The cultural-artistic rehabilitation activities intervention consists of three components: The Artistic Expression Module (poetry/singing), the Modified Baduanjin-Dance Integration and the Group Narrative Therapy. These were delivered in weekly sequences of 60, 90 and 30 min. Propensity score matching, inverse probability weighting, and linear regression assessed the effects on QoL, psychological symptoms, and self-management.</div></div><div><h3>Results</h3><div>Following propensity score matching and inverse probability weighting adjustments, the intervention group displayed greater overall QoL scores, kidney-specific QoL improvements, and enhanced self-management abilities relative to controls (P < 0.05). A strong positive association emerged between participation in creative-physical interventions and gains in QoL, mood stabilization, and self-management proficiency.</div></div><div><h3>Conclusion</h3><div>In MHD patients, integrated cultural-artistic rehabilitation activities enhance quality of life, self-management competence and psychological well-being. These results encourage greater patient engagement in cultural-artistic rehabilitation activities.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103289"},"PeriodicalIF":3.5,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Binaural beats for perioperative anxiety and pain: A systematic review and meta-analysis 双耳节拍治疗围手术期焦虑和疼痛：系统回顾和荟萃分析。

IF 3.5 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine

Pub Date : 2025-10-30 DOI: 10.1016/j.ctim.2025.103299

Jialin Xiong, Xin Jiang, Binyang Cai, Li Zhao, Qiang Zhang, Jie Luo

Background

Perioperative anxiety has a high prevalence, exacerbating hemodynamic fluctuations and postoperative pain. Compared with conventional music therapy, binaural beats (BB) audio distinctively modulates emotional pathways via cortical entrainment, potentially offering superior anxiolytic and analgesic efficacy in surgical settings.

Objective

This meta-analysis aimed to evaluate the effects of BB audio on perioperative anxiety, pain, and hemodynamic parameters in patients undergoing surgical procedures.

Methods

Randomized controlled trials (RCTs) published from database inception to December 2024 were retrieved from MEDLINE (via PubMed), Embase, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science. Studies examining the effects of perioperative BB audio on anxiety, pain, and hemodynamic parameters in surgical patients were included. The primary outcome was anxiety levels (measured by standardized scales). Secondary outcomes included pain, changes in hemodynamic parameters (systolic blood pressure, diastolic blood pressure, and heart rate), and incidence of adverse events (nausea, vomiting, dizziness, hearing impairment, etc.).

Results

Out of 318 studies initially identified, 15 studies were included. Compared to blank audio controls, BB significantly reduced perioperative anxiety (14 trials, n = 1047; SMD = − 1.38, 95 % CI: − 1.89 to − 0.87, P < 0.0001, I² = 91.6 %), postoperative pain (5 trials, n = 433; SMD = − 0.61, 95 % CI: − 1.03 to − 0.19, P = 0.0024, I² = 75.8 %), systolic blood pressure (6 trials, n = 436; MD = − 5.57 mmHg, 95 % CI: − 8.71 to − 2.44, P = 0.3041, I² = 17 %), and heart rate (MD = − 3.37 bpm, 95 % CI: − 5.45 to − 1.29, P = 0.3253, I² = 13.9 %), though effects on diastolic blood pressure were not significant (MD = − 2.33 mmHg, 95 % CI: −5.19 to 0.52, P = 0.0334, I² = 58.7 %). When compared to non-binaural beats (non-BB) audio, BB demonstrated superior reductions in anxiety (8 trials, n = 598; SMD = − 1.01, 95 % CI: − 1.99 to − 0.03, P < 0.0001; I² = 95.4 %) and postoperative pain (3 trials, n = 265; SMD = − 0.52, 95 % CI: − 0.77 to − 0.28, P = 0.9235, I² = 0 %).

Conclusion

Perioperative BB audio significantly reduces anxiety, alleviates pain, and stabilizes key hemodynamic parameters (systolic blood pressure, heart rate), outperforming non-BB audio. BB audio represents a promising non-pharmacological intervention, though inter-trial heterogeneity was substantial. Protocol standardization requires further high-quality RCTs.

背景：围手术期焦虑发生率高，加剧了血流动力学波动和术后疼痛。与传统的音乐治疗相比，双耳节拍（BB）音频通过皮质夹带独特地调节情绪通路，可能在手术环境中提供优越的抗焦虑和镇痛效果。目的：本荟萃分析旨在评估BB音频对外科手术患者围手术期焦虑、疼痛和血流动力学参数的影响。方法：从MEDLINE（通过PubMed）、Embase、Cochrane Central Register of controlled trials （Central）和Web of Science检索数据库建立至2024年12月发表的随机对照试验（RCTs）。研究包括围手术期BB音频对手术患者焦虑、疼痛和血流动力学参数的影响。主要结果是焦虑水平（用标准化量表测量）。次要结局包括疼痛、血流动力学参数改变（收缩压、舒张压和心率）和不良事件发生率（恶心、呕吐、头晕、听力障碍等）。结果：在最初确定的318项研究中，纳入了15项研究。与空白音频对照相比，BB显著降低围手术期焦虑(14项试验，n=1,047; SMD = -1.38, 95% CI: -1.89 ~ -0.87， P

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引用次数: 0

Clinical evidence on acupuncture for symptom improvement in multiple sclerosis 针刺对多发性硬化症状改善的临床证据。

IF 3.5 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine

Pub Date : 2025-10-28 DOI: 10.1016/j.ctim.2025.103276

Yao Chen , Yang Cui , Xinyu Zhou , Shuo Zhang , Ze Wang , Juandi Yang , Xiangxin Zeng , Yuhuai Guo , Zhongren Sun , Hongna Yin

Background

Clinical trials on acupuncture for multiple sclerosis (MS) have been growing, but the findings are ongoing controversy.

Objective

To evaluate the existing randomized clinical trials (RCTs) for evidence of the efficacy of acupuncture on MS.

Methods

We searched PubMed, Embase, CENTRAL, Web of Science, four Chinese-language databases, clinical research registration, gray literature, and reference lists of the selected studies. We evaluated the risk of bias in the included studies with RoB 2, and performed meta-analysis, subgroup analysis, meta-regression, and publication bias detection using STATA version 15.1. Moreover, we assessed the certainty of evidence using the GRADE approach. The protocol for this review was registered with PROSPERO (Prospective Register of Systematic Reviews) (CRD42024530800).

Results

A total of 11 RCTs (with 574 patients) were included in the study. The meta-analysis results showed that acupuncture, when combined with medicine, is more effective at improving disability status and enhancing the quality of life than medicine alone Acupuncture-related adverse events were rare and mild. The evidence grade was generally low because of the substantial heterogeneity among studies.

Conclusions

Acupuncture therapies are potential treatment options for MS, and are relatively safe. However, owing to the limitations of this study, these conclusions should be interpreted with caution.

背景：针灸治疗多发性硬化症（MS）的临床试验越来越多，但研究结果仍存在争议。目的：评价针刺治疗多发性硬化的随机临床试验（rct）。方法：检索PubMed、Embase、CENTRAL、Web of Science、4个中文数据库、临床研究注册、灰色文献和入选研究的参考文献。我们使用RoB 2评估纳入研究的偏倚风险，并使用STATA 15.1版本进行meta分析、亚组分析、meta回归和发表偏倚检测。此外，我们使用GRADE方法评估证据的确定性。本综述的方案已在PROSPERO（前瞻性系统评价注册系统）注册（CRD42024530800）。结果：共纳入11项rct（574例患者）。meta分析结果显示，针灸与药物联合使用在改善残疾状况和提高生活质量方面比单独使用药物更有效，针灸相关不良事件罕见且轻微。由于研究之间存在很大的异质性，证据等级普遍较低。结论：针灸治疗是多发性硬化症的潜在治疗选择，且相对安全。然而，由于本研究的局限性，这些结论应谨慎解释。

{"title":"Clinical evidence on acupuncture for symptom improvement in multiple sclerosis","authors":"Yao Chen , Yang Cui , Xinyu Zhou , Shuo Zhang , Ze Wang , Juandi Yang , Xiangxin Zeng , Yuhuai Guo , Zhongren Sun , Hongna Yin","doi":"10.1016/j.ctim.2025.103276","DOIUrl":"10.1016/j.ctim.2025.103276","url":null,"abstract":"<div><h3>Background</h3><div>Clinical trials on acupuncture for multiple sclerosis (MS) have been growing, but the findings are ongoing controversy.</div></div><div><h3>Objective</h3><div>To evaluate the existing randomized clinical trials (RCTs) for evidence of the efficacy of acupuncture on MS.</div></div><div><h3>Methods</h3><div>We searched PubMed, Embase, CENTRAL, Web of Science, four Chinese-language databases, clinical research registration, gray literature, and reference lists of the selected studies. We evaluated the risk of bias in the included studies with RoB 2, and performed meta-analysis, subgroup analysis, meta-regression, and publication bias detection using STATA version 15.1. Moreover, we assessed the certainty of evidence using the GRADE approach. The protocol for this review was registered with PROSPERO (Prospective Register of Systematic Reviews) (CRD42024530800).</div></div><div><h3>Results</h3><div>A total of 11 RCTs (with 574 patients) were included in the study. The meta-analysis results showed that acupuncture, when combined with medicine, is more effective at improving disability status and enhancing the quality of life than medicine alone Acupuncture-related adverse events were rare and mild. The evidence grade was generally low because of the substantial heterogeneity among studies.</div></div><div><h3>Conclusions</h3><div>Acupuncture therapies are potential treatment options for MS, and are relatively safe. However, owing to the limitations of this study, these conclusions should be interpreted with caution.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103276"},"PeriodicalIF":3.5,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145399970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0