Pub Date : 2025-10-31DOI: 10.1016/j.ctim.2025.103292
Chu Liu, Jiling Zou, Chu Zhang, Lin Zhu, Jun Li
Objective
Sarcopenia, characterized by progressive loss of skeletal muscle mass, strength, and function, significantly impairs quality of life in the elderly. This study systematically evaluated the effects of Fitness Qigong (including Baduanjin, Wu Qin Xi, and Yi Jin Jing) on muscle function in elderly patients with sarcopenia.
Methods
We searched eight electronic databases (e.g., PubMed, CINAHL) from inception to January 22, 2024, for randomized controlled trials (RCTs). Qualitative and quantitative analyses were conducted using RevMan 5.4 to assess grip strength, sit-to-stand time, gait speed, Timed Up-and-Go Test (TUGT) time, and peak muscle torque.
Results
Seventeen RCTs involving 1029 patients were included. Fitness Qigong significantly improved grip strength (MD = 2.39, 95 % CI [1.42, 3.36], P < 0.05). After sensitivity analyses to address heterogeneity, Fitness Qigong also significantly improved sit-to-stand time (MD = 2.27, 95 % CI [1.74, 2.80], P < 0.001) and gait speed (MD = 0.04, 95 % CI [0.01, 0.08], P = 0.02). Additionally, it reduced TUGT time (MD = −3.20, 95 % CI [-4.35, −2.04], P < 0.05) and increased peak muscle torque (MD = 11.19, 95 % CI [2.70, 19.68], P = 0.01).
Conclusion
Fitness Qigong is an effective, safe, low-intensity, and cost-effective exercise for improving muscle function in elderly patients with sarcopenia.
目的：骨骼肌减少症以骨骼肌质量、力量和功能的进行性丧失为特征，严重影响老年人的生活质量。本研究系统评价健身气功（包括八段筋、五秦练、益筋经）对老年肌少症患者肌肉功能的影响。方法：我们检索了8个电子数据库（如PubMed， CINAHL），从成立到2024年1月22日，随机对照试验（RCTs）。采用RevMan 5.4进行定性和定量分析，评估握力、坐立时间、步态速度、定时起-走测试（Timed Up-and-Go Test， TUGT）时间和肌肉峰值扭矩。结果：纳入17项随机对照试验，共1029例患者。健身气功显著提高握力（MD = 2.39, 95% CI [1.42, 3.36], P < 0.05）。在对异质性进行敏感性分析后，健身气功还显著改善了坐姿到站立的时间（MD = 2.27, 95% CI [1.74, 2.80], P < 0.001）和步态速度（MD = 0.04, 95% CI [0.01, 0.08], P = 0.02）。此外，它缩短了TUGT时间（MD = -3.20, 95% CI [-4.35, -2.04], P < 0.05），增加了肌肉峰值扭矩（MD = 11.19, 95% CI [2.70, 19.68], P = 0.01）。结论：健身气功是改善老年肌少症患者肌肉功能的一种有效、安全、低强度、低成本的运动方式。系统评审注册号：https://www.crd.york.ac.uk/PROSPERO/，标识符注册号。CRD42024592804。
{"title":"Effects of Fitness Qigong on muscle function in elderly patients with sarcopenia: A systematic review and meta-analysis of randomized controlled trials","authors":"Chu Liu, Jiling Zou, Chu Zhang, Lin Zhu, Jun Li","doi":"10.1016/j.ctim.2025.103292","DOIUrl":"10.1016/j.ctim.2025.103292","url":null,"abstract":"<div><h3>Objective</h3><div>Sarcopenia, characterized by progressive loss of skeletal muscle mass, strength, and function, significantly impairs quality of life in the elderly. This study systematically evaluated the effects of Fitness Qigong (including Baduanjin, Wu Qin Xi, and Yi Jin Jing) on muscle function in elderly patients with sarcopenia.</div></div><div><h3>Methods</h3><div>We searched eight electronic databases (e.g., PubMed, CINAHL) from inception to January 22, 2024, for randomized controlled trials (RCTs). Qualitative and quantitative analyses were conducted using RevMan 5.4 to assess grip strength, sit-to-stand time, gait speed, Timed Up-and-Go Test (TUGT) time, and peak muscle torque.</div></div><div><h3>Results</h3><div>Seventeen RCTs involving 1029 patients were included. Fitness Qigong significantly improved grip strength (MD = 2.39, 95 % CI [1.42, 3.36], P < 0.05). After sensitivity analyses to address heterogeneity, Fitness Qigong also significantly improved sit-to-stand time (MD = 2.27, 95 % CI [1.74, 2.80], P < 0.001) and gait speed (MD = 0.04, 95 % CI [0.01, 0.08], P = 0.02). Additionally, it reduced TUGT time (MD = −3.20, 95 % CI [-4.35, −2.04], P < 0.05) and increased peak muscle torque (MD = 11.19, 95 % CI [2.70, 19.68], P = 0.01).</div></div><div><h3>Conclusion</h3><div>Fitness Qigong is an effective, safe, low-intensity, and cost-effective exercise for improving muscle function in elderly patients with sarcopenia.</div></div><div><h3>Systematic review registration number</h3><div><span><span>https://www.crd.york.ac.uk/PROSPERO</span><svg><path></path></svg></span>/， identifier registration number. CRD42024592804</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103292"},"PeriodicalIF":3.5,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-31DOI: 10.1016/j.ctim.2025.103293
Yanming Zhang , Cheng Tan , Diyue Liu , Saier Yang , Lei Shi , Mingchen Zhao
Introduction
This study aims to analyze the prevalence characteristics of negative emotions among Chinese residents and explore the impact of participating in horticultural activities on negative emotions of Chinese residents.
Methods
Data for this study were obtained from the 2022 China Residents' Psychological and Behavioral Investigation and Research Program. This study used propensity score matching (PSM) to balance the variables and employed both binary and multiple logistic regression analyses to investigate the effects of horticultural activity participation (including frequency and duration) on levels of depression, anxiety, and loneliness.
Results
The prevalence of depression, anxiety, and loneliness among respondents was 56.5 %, 45.7 %, and 44.7 %, respectively. Female respondents exhibited significantly higher risks of depression (P < 0.01) and anxiety (P < 0.05) compared to males. Adults aged 18–45 years showed markedly increased vulnerability to depression and anxiety relative to other age groups. Retired and unemployed individuals reported substantially elevated levels of depression and anxiety compared to employed respondents. Rural residents demonstrated significantly higher risks of negative psychological emotions than urban residents (P < 0.01). Participation in horticultural activities was significantly associated with reduced levels of depression (P < 0.01) and anxiety (P < 0.05), with more frequent participation correlating with stronger protective effects. Regarding loneliness, significant associations were found with gender, age, occupation, education level, and involvement in horticultural activities, including frequency, duration, and acceptance of horticultural therapy (all P < 0.05).
Conclusions
The prevalence of negative emotions among Chinese residents is relatively high, and horticultural activity participation was associated with reduced levels of negative psychological symptoms. Governments, social organizations, and other stakeholders should promote related activities with frequencies and durations that are scientifically grounded and tailored to individual needs. In addition, to comprehensively enhance people's mental health, attention must be given to the characteristics and needs of different groups.
{"title":"The impact of horticultural activities on negative psychological emotions among Chinese residents: A cross-sectional study of a national representative sample based on propensity score matching","authors":"Yanming Zhang , Cheng Tan , Diyue Liu , Saier Yang , Lei Shi , Mingchen Zhao","doi":"10.1016/j.ctim.2025.103293","DOIUrl":"10.1016/j.ctim.2025.103293","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aims to analyze the prevalence characteristics of negative emotions among Chinese residents and explore the impact of participating in horticultural activities on negative emotions of Chinese residents.</div></div><div><h3>Methods</h3><div>Data for this study were obtained from the 2022 China Residents' Psychological and Behavioral Investigation and Research Program. This study used propensity score matching (PSM) to balance the variables and employed both binary and multiple logistic regression analyses to investigate the effects of horticultural activity participation (including frequency and duration) on levels of depression, anxiety, and loneliness.</div></div><div><h3>Results</h3><div>The prevalence of depression, anxiety, and loneliness among respondents was 56.5 %, 45.7 %, and 44.7 %, respectively. Female respondents exhibited significantly higher risks of depression (<em>P </em>< 0.01) and anxiety (<em>P</em> < 0.05) compared to males. Adults aged 18–45 years showed markedly increased vulnerability to depression and anxiety relative to other age groups. Retired and unemployed individuals reported substantially elevated levels of depression and anxiety compared to employed respondents. Rural residents demonstrated significantly higher risks of negative psychological emotions than urban residents (<em>P</em> < 0.01). Participation in horticultural activities was significantly associated with reduced levels of depression (<em>P</em> < 0.01) and anxiety (<em>P</em> < 0.05), with more frequent participation correlating with stronger protective effects. Regarding loneliness, significant associations were found with gender, age, occupation, education level, and involvement in horticultural activities, including frequency, duration, and acceptance of horticultural therapy (all <em>P </em>< 0.05).</div></div><div><h3>Conclusions</h3><div>The prevalence of negative emotions among Chinese residents is relatively high, and horticultural activity participation was associated with reduced levels of negative psychological symptoms. Governments, social organizations, and other stakeholders should promote related activities with frequencies and durations that are scientifically grounded and tailored to individual needs. In addition, to comprehensively enhance people's mental health, attention must be given to the characteristics and needs of different groups.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103293"},"PeriodicalIF":3.5,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-31DOI: 10.1016/j.ctim.2025.103286
Sicheng Li , Shengjie Wang , Sisi Li , Chao Liu , Jialing Sun , Jingjing Cao , Xiaoyang Cui , Qin Han , Zhengliang Li , Fan Wu
Background
Functional constipation is one of the most common complications among stroke patients, significantly impacting their quality of life. This study examined the effects of abdominal acupuncture on constipation symptoms, gut microbiota, and neurological function in post-stroke patients with functional constipation, based on the brain–gut–microbiota axis, to improve patient prognosis.
Method
Seventy-five patients with post-stroke functional constipation were randomly assigned either to the abdominal acupuncture (AA) group or the routine treatment (RT) group. Both groups received standard medication and rehabilitation for stroke. While the routine therapy was administered to both groups of patients, the AA group patients underwent AA. Constipation symptom scores, fecal intestinal flora, National Institutes of Health Stroke Scale (NIHSS), Fugl-Meyer Assessment (FMA), Modified Barthel Index (MBI), and Limits of Stability (LOS) were evaluated in both groups before and after treatment. Resting-state functional near-infrared spectroscopy was also assessed before and after treatment.
Results
When compared with pre-treatment, both groups displayed improvements in their constipation symptom scores, NIHSS, FMA, MBI, and LOS after treatment. Levels of Escherichia coli and Enterococcus in feces decreased, while the levels of Bifidobacterium, Lactobacillus, and Bacteroides increased. These improvements were significantly greater in the AA group than in the RT group (P < 0.01 or P < 0.05). Furthermore, a significant difference was noted in cortical functional activity between the two groups after treatment.
Conclusion
AA can effectively relieve functional constipation after stroke, regulate intestinal flora, enhance neurological function, and lower the disability rate.
International Traditional Medicine Clinical Trial Registry (ITMCTR):http://itmctr.ccebtcm.org.cn/, ITMCTR2025001532.
{"title":"Brain–gut–microbiota axis: An effective target of abdominal acupuncture therapy for post-stroke functional constipation","authors":"Sicheng Li , Shengjie Wang , Sisi Li , Chao Liu , Jialing Sun , Jingjing Cao , Xiaoyang Cui , Qin Han , Zhengliang Li , Fan Wu","doi":"10.1016/j.ctim.2025.103286","DOIUrl":"10.1016/j.ctim.2025.103286","url":null,"abstract":"<div><h3>Background</h3><div>Functional constipation is one of the most common complications among stroke patients, significantly impacting their quality of life. This study examined the effects of abdominal acupuncture on constipation symptoms, gut microbiota, and neurological function in post-stroke patients with functional constipation, based on the brain–gut–microbiota axis, to improve patient prognosis.</div></div><div><h3>Method</h3><div>Seventy-five patients with post-stroke functional constipation were randomly assigned either to the abdominal acupuncture (AA) group or the routine treatment (RT) group. Both groups received standard medication and rehabilitation for stroke. While the routine therapy was administered to both groups of patients, the AA group patients underwent AA. Constipation symptom scores, fecal intestinal flora, National Institutes of Health Stroke Scale (NIHSS), Fugl-Meyer Assessment (FMA), Modified Barthel Index (MBI), and Limits of Stability (LOS) were evaluated in both groups before and after treatment. Resting-state functional near-infrared spectroscopy was also assessed before and after treatment.</div></div><div><h3>Results</h3><div>When compared with pre-treatment, both groups displayed improvements in their constipation symptom scores, NIHSS, FMA, MBI, and LOS after treatment. Levels of <em>Escherichia coli</em> and <em>Enterococcus</em> in feces decreased, while the levels of <em>Bifidobacterium</em>, <em>Lactobacillus</em>, and <em>Bacteroides</em> increased. These improvements were significantly greater in the AA group than in the RT group (<em>P</em> < 0.01 or <em>P</em> < 0.05). Furthermore, a significant difference was noted in cortical functional activity between the two groups after treatment.</div></div><div><h3>Conclusion</h3><div>AA can effectively relieve functional constipation after stroke, regulate intestinal flora, enhance neurological function, and lower the disability rate.</div><div><em>International Traditional Medicine Clinical Trial Registry (ITMCTR):</em> <span><span>http://itmctr.ccebtcm.org.cn/</span><svg><path></path></svg></span>, ITMCTR2025001532.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103286"},"PeriodicalIF":3.5,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-31DOI: 10.1016/j.ctim.2025.103303
Qiu-Song Shen , Qiao Wang , Hou-Ming Kan , Xin-Li Shi , Nai-Fa Li , Xu Zhang
Background
Transcranial direct current stimulation (tDCS), as a supplementary plan during the perioperative period, is currently a novel exploration of using neuromodulation techniques to improve postoperative symptoms.
Methods
We searched Embase, PubMed, EBSCO, Web of Science, Scopus, and Cochrane Library databases on February 17, 2025. The primary outcomes included postoperative opioid drug consumption and pain score. The secondary outcomes included fatigue, anxiety, depression, quality of recovery, sleep quality, and adverse events. The study was conducted using Review Manager 5.4 software.
Results
We ultimately included 13 trials, including 827 participants (442 in the real tDCS group and 385 in the sham group). Within these trials, two had some concerns, and eleven were low-risk. In terms of primary outcomes, tDCS could significantly reduce postoperative opioid consumption (SMD = −0.52, 95 %CI = [-0.77, −0.27]; P ＜ 0.001), pain score (SMD = −0.48, 95 %CI = [-0.66, −0.29], P < 0.001). For secondary outcome, tDCS led to a significant decrease in the fatigue score (SMD = −4.35, 95 %CI = [-4.73, −3.98], P ＜ 0.001). However, there were no statistically differences in anxiety (SMD = −0.98, 95 % CI = [-2.16, 0.21], P = 0.110). tDCS could increase adverse event (RR = 3.88, 95 % CI = [1.64, 9.19], P = 0.002), but these events were mild and temporary. Due to the limited number of trials on postoperative recovery quality, depression, and sleep quality, we conducted only a review and did not include these outcomes in the meta-analysis.
Conclusions
tDCS can reduce postoperative opioid consumption and effectively alleviate postoperative pain. Regarding secondary outcomes, although the results suggest it may reduce postoperative fatigue, this conclusion requires further validation due to the limited number of studies included.More studies are needed in the future to provide evidence on the effects of tDCS on fatigue, anxiety, depression, quality of recovery and sleep quality.
Keypoints
•
Question: Does the use of tDCS during the perioperative period help diminish postoperative opioid use and alleviate pain scores?
•
Findings: The current evidence suggests using tDCS during the perioperative period to reduce postoperative opioid consumption and lower pain scores.
•
Meaning: tDCS is currently a key focus in exploring neuromodulation techniques to improve postoperative symptoms.
背景：经颅直流电刺激（Transcranial direct current stimulation, tDCS）作为围手术期的辅助方案，是目前利用神经调节技术改善术后症状的新探索。方法：我们于2025年2月17日检索Embase、PubMed、EBSCO、Web of Science、Scopus和Cochrane Library数据库。主要结局包括术后阿片类药物消耗和疼痛评分。次要结局包括疲劳、焦虑、抑郁、恢复质量、睡眠质量和不良事件。本研究使用Review Manager 5.4软件进行。结果：我们最终纳入了13项试验，包括827名参与者（真实tDCS组442名，假手术组385名）。在这些试验中，2例存在一些担忧，11例风险较低。在主要结局方面，tDCS可显著降低术后阿片类药物消耗（SMD = -0.52, 95%CI = [-0.77, -0.27]; P < 0.001）、疼痛评分（SMD = -0.48, 95%CI = [-0.66, -0.29], P < 0.001）。对于次要结局，tDCS导致疲劳评分显著降低（SMD = -4.35, 95%CI = [-4.73, -3.98], P < 0.001）。但两组在焦虑方面无统计学差异（SMD = -0.98, 95% CI = [-2.16, 0.21], P = 0.110）。tDCS可增加不良事件（RR = 3.88, 95% CI = [1.64, 9.19], P = 0.002），但这些不良事件是轻微且暂时的。由于关于术后恢复质量、抑郁和睡眠质量的试验数量有限，我们只进行了一项综述，未将这些结果纳入meta分析。结论：tDCS可减少术后阿片类药物消耗，有效缓解术后疼痛。至于次要结局，虽然结果表明它可以减轻术后疲劳，但由于纳入的研究数量有限，这一结论需要进一步验证。tDCS对疲劳、焦虑、抑郁、恢复质量和睡眠质量的影响有待进一步研究。重点:
{"title":"The effect of tDCS on postoperative opioid consumption and pain after general anesthesia: A systematic review and meta-analysis of randomized controlled trials","authors":"Qiu-Song Shen , Qiao Wang , Hou-Ming Kan , Xin-Li Shi , Nai-Fa Li , Xu Zhang","doi":"10.1016/j.ctim.2025.103303","DOIUrl":"10.1016/j.ctim.2025.103303","url":null,"abstract":"<div><h3>Background</h3><div>Transcranial direct current stimulation (tDCS), as a supplementary plan during the perioperative period, is currently a novel exploration of using neuromodulation techniques to improve postoperative symptoms.</div></div><div><h3>Methods</h3><div>We searched Embase, PubMed, EBSCO, Web of Science, Scopus, and Cochrane Library databases on February 17, 2025. The primary outcomes included postoperative opioid drug consumption and pain score. The secondary outcomes included fatigue, anxiety, depression, quality of recovery, sleep quality, and adverse events. The study was conducted using Review Manager 5.4 software.</div></div><div><h3>Results</h3><div>We ultimately included 13 trials, including 827 participants (442 in the real tDCS group and 385 in the sham group). Within these trials, two had some concerns, and eleven were low-risk. In terms of primary outcomes, tDCS could significantly reduce postoperative opioid consumption (SMD = −0.52, 95 %CI = [-0.77, −0.27]; <em>P</em> ＜ 0.001), pain score (SMD = −0.48, 95 %CI = [-0.66, −0.29], <em>P</em> < 0.001). For secondary outcome, tDCS led to a significant decrease in the fatigue score (SMD = −4.35, 95 %CI = [-4.73, −3.98], <em>P</em> ＜ 0.001). However, there were no statistically differences in anxiety (SMD = −0.98, 95 % CI = [-2.16, 0.21], <em>P</em> = 0.110). tDCS could increase adverse event (RR = 3.88, 95 % CI = [1.64, 9.19], <em>P</em> = 0.002), but these events were mild and temporary. Due to the limited number of trials on postoperative recovery quality, depression, and sleep quality, we conducted only a review and did not include these outcomes in the meta-analysis.</div></div><div><h3>Conclusions</h3><div>tDCS can reduce postoperative opioid consumption and effectively alleviate postoperative pain. Regarding secondary outcomes, although the results suggest it may reduce postoperative fatigue, this conclusion requires further validation due to the limited number of studies included.More studies are needed in the future to provide evidence on the effects of tDCS on fatigue, anxiety, depression, quality of recovery and sleep quality.</div></div><div><h3>Keypoints</h3><div><ul><li><span>•</span><span><div>Question: Does the use of tDCS during the perioperative period help diminish postoperative opioid use and alleviate pain scores?</div></span></li></ul><ul><li><span>•</span><span><div>Findings: The current evidence suggests using tDCS during the perioperative period to reduce postoperative opioid consumption and lower pain scores.</div></span></li></ul></div><div><ul><li><span>•</span><span><div>Meaning: tDCS is currently a key focus in exploring neuromodulation techniques to improve postoperative symptoms.</div></span></li></ul></div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103303"},"PeriodicalIF":3.5,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-31DOI: 10.1016/j.ctim.2025.103296
Yi-Ren Wang , Ying-Chih Ho , Yueh-Chiao Yeh
Background
Hypertension commonly manifests with anxiety, fatigue, and sleep disturbances that negatively impact quality of life. Lavender essential oil is widely used in complementary therapies for its anxiolytic, hypotensive, and sedative properties. This study aimed to investigate the short- and long-term effects of inhaled lavender essential oil, delivered via a magnetic face mask clip, on psychological and physiological outcomes in middle-aged adults with hypertension.
Methods
Fifty-eight hypertensive adults aged 40–60 years were randomly assigned to either an intervention group (lavender essential oil, n = 30) or a placebo group (sweet almond oil, n = 28). Assessments were conducted at baseline, immediately after a single 15-minute inhalation session, and following daily 15-minute sessions over seven consecutive days. Outcome measures included the State-Trait Anxiety Inventory (STAI), Chalder Fatigue Questionnaire (CFQ), systolic (SBP) and diastolic blood pressure (DBP), and the Verran and Snyder-Halpern Sleep Scale (VHS).
Results
At baseline, both groups were demographically comparable. Immediately post-intervention, the aroma group showed significantly greater reductions in anxiety (STAI: −15.7 vs. −0.9, p < .001) and SBP (p = .025). After seven days, the intervention group demonstrated significant improvements across all measures: STAI (−15.6 vs. −0.6, p < .001), fatigue (CFQ: −4.8 vs. −0.9, p = .011), SBP (p = .002) and DBP (p = .033), and sleep quality (VHS: +165.0 vs. +4.7, p < .001).
Conclusion
Inhalation of lavender essential oil via a mask clip may serve as an effective complementary approach for improving emotional and physiological outcomes in hypertensive adults.
背景：高血压通常表现为焦虑、疲劳和睡眠障碍，对生活质量产生负面影响。薰衣草精油因其抗焦虑、降压和镇静的特性被广泛用于补充疗法。本研究旨在探讨通过磁性面罩夹吸入薰衣草精油对中年高血压患者心理和生理结果的短期和长期影响。方法：58名40-60岁的高血压成年人随机分为干预组（薰衣草精油，n = 30）和安慰剂组（甜杏仁油，n = 28）。评估在基线、单次15分钟吸入后立即进行，以及连续7天每天15分钟吸入后进行。结果测量包括状态-特质焦虑量表（STAI）、Chalder疲劳问卷（CFQ）、收缩压（SBP）和舒张压（DBP）以及Verran和Snyder-Halpern睡眠量表（VHS）。结果：在基线时，两组在人口统计学上具有可比性。干预后立即，芳香组表现出明显更大的焦虑减少（STAI: -15.7 vs -0.9, p）。结论：通过面罩夹吸入薰衣草精油可能是改善高血压成人情绪和生理结果的有效补充方法。
{"title":"Short- and long-term effects of inhaled lavender essential oil on anxiety, fatigue, blood pressure, and sleep quality in middle-aged adults with hypertension: A randomized placebo-controlled pilot study","authors":"Yi-Ren Wang , Ying-Chih Ho , Yueh-Chiao Yeh","doi":"10.1016/j.ctim.2025.103296","DOIUrl":"10.1016/j.ctim.2025.103296","url":null,"abstract":"<div><h3>Background</h3><div>Hypertension commonly manifests with anxiety, fatigue, and sleep disturbances that negatively impact quality of life. Lavender essential oil is widely used in complementary therapies for its anxiolytic, hypotensive, and sedative properties. This study aimed to investigate the short- and long-term effects of inhaled lavender essential oil, delivered via a magnetic face mask clip, on psychological and physiological outcomes in middle-aged adults with hypertension.</div></div><div><h3>Methods</h3><div>Fifty-eight hypertensive adults aged 40–60 years were randomly assigned to either an intervention group (lavender essential oil, <em>n</em> = 30) or a placebo group (sweet almond oil, <em>n</em> = 28). Assessments were conducted at baseline, immediately after a single 15-minute inhalation session, and following daily 15-minute sessions over seven consecutive days. Outcome measures included the State-Trait Anxiety Inventory (STAI), Chalder Fatigue Questionnaire (CFQ), systolic (SBP) and diastolic blood pressure (DBP), and the Verran and Snyder-Halpern Sleep Scale (VHS).</div></div><div><h3>Results</h3><div>At baseline, both groups were demographically comparable. Immediately post-intervention, the aroma group showed significantly greater reductions in anxiety (STAI: −15.7 vs. −0.9, <em>p</em> < .001) and SBP (<em>p</em> = .025). After seven days, the intervention group demonstrated significant improvements across all measures: STAI (−15.6 vs. −0.6, <em>p</em> < .001), fatigue (CFQ: −4.8 vs. −0.9, <em>p</em> = .011), SBP (<em>p</em> = .002) and DBP (<em>p</em> = .033), and sleep quality (VHS: +165.0 vs. +4.7, <em>p</em> < .001).</div></div><div><h3>Conclusion</h3><div>Inhalation of lavender essential oil via a mask clip may serve as an effective complementary approach for improving emotional and physiological outcomes in hypertensive adults.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103296"},"PeriodicalIF":3.5,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-31DOI: 10.1016/j.ctim.2025.103283
Lizhen Gan , Qi Tang , Zhi Zhang , Carrere Rivera Camille , Aníbal Simón Sandoval , Xinyi He , Lutao Li , Jian Hu , Qingbo Wei , Yunchuan Wu
Objective
The aim of this study is to evaluate the clinical efficacy of Health Qigong Walking Practice in alleviating anxiety and improving metabolic profiles in patients with type 2 diabetes mellitus (T2DM), and to explore the underlying mechanisms using serum metabolomics.
Methods
60 patients with a diagnosis of T2DM with anxiety were randomly assigned to a health education group (HEG), an aerobic exercise group (AEG), and a Health Qigong Walking Practice group （HQWPG） (n = 20 per group) using a table of random numbers. Self-Rating Anxiety Scale (SAS) scores and glucose-lipid metabolism markers—including fasting blood glucose (FBG), 2-hour postprandial blood glucose (PBG), glycosylated hemoglobin (HbA1c), triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL), and low-density lipoprotein (LDL)—were assessed before and after a 12-week intervention. Untargeted serum metabolomics was conducted in the QTG to identify differential metabolites and metabolic pathways.
Results
After 12 weeks, both the HQWPG and AEG showed significant reductions in anxiety scores compared to the HEG (P < 0.05). However, the HQWPG demonstrated significantly greater improvements in glycemic control, particularly in PBG, compared to both control groups (P < 0.05). While conventional aerobic exercise showed limited effects on metabolic markers in this study, the holistic nature of Health Qigong Walking Practice, integrating movement, breathwork, and mindfulness, likely provided additional regulatory benefits. Metabolomics in the HQWPG revealed significant changes in metabolites, including glycyltyrosine, N-acetylmethionine, and glutamic acid, and pathway analysis highlighted alterations in histidine metabolism and nitrogen metabolism.
Conclusion
Health Qigong Walking Practice significantly reduces anxiety and improves glucose-lipid metabolism in T2DM patients with anxiety. Its superiority over standard aerobic exercise in glycemic control may be mediated through the integrated regulation of movement, breath, and mind, which modulates key amino acid and nitrogen metabolism pathways. This mind-body intervention offers a promising adjunctive therapy for T2DM.
{"title":"Effects of Health Qigong Walking Practice on anxiety and serum metabolites in patients with Type 2 Diabetes Mellitus: A randomized controlled trial","authors":"Lizhen Gan , Qi Tang , Zhi Zhang , Carrere Rivera Camille , Aníbal Simón Sandoval , Xinyi He , Lutao Li , Jian Hu , Qingbo Wei , Yunchuan Wu","doi":"10.1016/j.ctim.2025.103283","DOIUrl":"10.1016/j.ctim.2025.103283","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study is to evaluate the clinical efficacy of Health Qigong Walking Practice in alleviating anxiety and improving metabolic profiles in patients with type 2 diabetes mellitus (T2DM), and to explore the underlying mechanisms using serum metabolomics.</div></div><div><h3>Methods</h3><div>60 patients with a diagnosis of T2DM with anxiety were randomly assigned to a health education group (HEG), an aerobic exercise group (AEG), and a Health Qigong Walking Practice group （HQWPG） (n = 20 per group) using a table of random numbers. Self-Rating Anxiety Scale (SAS) scores and glucose-lipid metabolism markers—including fasting blood glucose (FBG), 2-hour postprandial blood glucose (PBG), glycosylated hemoglobin (HbA1c), triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL), and low-density lipoprotein (LDL)—were assessed before and after a 12-week intervention. Untargeted serum metabolomics was conducted in the QTG to identify differential metabolites and metabolic pathways.</div></div><div><h3>Results</h3><div>After 12 weeks, both the HQWPG and AEG showed significant reductions in anxiety scores compared to the HEG (P < 0.05). However, the HQWPG demonstrated significantly greater improvements in glycemic control, particularly in PBG, compared to both control groups (P < 0.05). While conventional aerobic exercise showed limited effects on metabolic markers in this study, the holistic nature of Health Qigong Walking Practice, integrating movement, breathwork, and mindfulness, likely provided additional regulatory benefits. Metabolomics in the HQWPG revealed significant changes in metabolites, including glycyltyrosine, N-acetylmethionine, and glutamic acid, and pathway analysis highlighted alterations in histidine metabolism and nitrogen metabolism.</div></div><div><h3>Conclusion</h3><div>Health Qigong Walking Practice significantly reduces anxiety and improves glucose-lipid metabolism in T2DM patients with anxiety. Its superiority over standard aerobic exercise in glycemic control may be mediated through the integrated regulation of movement, breath, and mind, which modulates key amino acid and nitrogen metabolism pathways. This mind-body intervention offers a promising adjunctive therapy for T2DM.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103283"},"PeriodicalIF":3.5,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-31DOI: 10.1016/j.ctim.2025.103285
De-ta Chen , Hai-xia Zhu , Zi-jian Wan , Tian-you Fan , Jing-liang Gu , Xin-hua Zhan , Xiao-ping Sheng
Objective
To systematically evaluate and meta-analyze the clinical efficacy of manual therapy for lumbar disc herniation (LDH), with emphasis on its effects on pain relief, functional recovery, and inflammatory modulation.
Methods
A comprehensive search of both Chinese and international databases was performed to identify 47 randomized controlled trials (RCTs) of manual therapy for LDH. Meta-analyses were conducted using RevMan 5.4 and Stata 18.0. Primary outcomes included clinical effectiveness, pain scores, functional measures assessed by the Japanese Orthopaedic Association (JOA) score and the Oswestry Disability Index (ODI), and inflammatory cytokines (TNF-α, IL-1β, IL-6). Sensitivity analyses, publication bias assessment, and GRADE evidence grading were also performed.
Results
A total of 4480 patients were included. Manual therapy was associated with superior clinical effectiveness (RR = 1.20, 95 % CI: 1.15–1.25), significant reductions in pain scores (SMD = 1.23, 95 % CI: 0.98–1.49), and improved functional outcomes (JOA SMD = 1.42, 95 % CI: 1.07–1.77; mean ODI reduction: 14.47 points). Limited evidence also suggested reductions in inflammatory markers, including TNF-α (SMD = 2.25), IL-1β (SMD = 1.45), and IL-6 (SMD = 0.66). Sensitivity analyses confirmed robustness of the pooled results, while publication bias was minimal. According to GRADE, the certainty of evidence was moderate for pain relief and clinical effectiveness and low for other outcomes.
Conclusion
Manual therapy demonstrates consistent short-term benefits for patients with LDH across multiple domains, including pain, function, and inflammation. However, since most included trials were conducted in China and were of low-to-moderate methodological quality, the certainty of evidence should be considered moderate to low, and findings should be interpreted with caution. Further high-quality, multi-center international RCTs are warranted to strengthen the evidence base.
{"title":"Clinical efficacy of chinese manual therapy for lumbar disc herniation: A systematic review and meta-analysis","authors":"De-ta Chen , Hai-xia Zhu , Zi-jian Wan , Tian-you Fan , Jing-liang Gu , Xin-hua Zhan , Xiao-ping Sheng","doi":"10.1016/j.ctim.2025.103285","DOIUrl":"10.1016/j.ctim.2025.103285","url":null,"abstract":"<div><h3>Objective</h3><div>To systematically evaluate and meta-analyze the clinical efficacy of manual therapy for lumbar disc herniation (LDH), with emphasis on its effects on pain relief, functional recovery, and inflammatory modulation.</div></div><div><h3>Methods</h3><div>A comprehensive search of both Chinese and international databases was performed to identify 47 randomized controlled trials (RCTs) of manual therapy for LDH. Meta-analyses were conducted using RevMan 5.4 and Stata 18.0. Primary outcomes included clinical effectiveness, pain scores, functional measures assessed by the Japanese Orthopaedic Association (JOA) score and the Oswestry Disability Index (ODI), and inflammatory cytokines (TNF-α, IL-1β, IL-6). Sensitivity analyses, publication bias assessment, and GRADE evidence grading were also performed.</div></div><div><h3>Results</h3><div>A total of 4480 patients were included. Manual therapy was associated with superior clinical effectiveness (RR = 1.20, 95 % CI: 1.15–1.25), significant reductions in pain scores (SMD = 1.23, 95 % CI: 0.98–1.49), and improved functional outcomes (JOA SMD = 1.42, 95 % CI: 1.07–1.77; mean ODI reduction: 14.47 points). Limited evidence also suggested reductions in inflammatory markers, including TNF-α (SMD = 2.25), IL-1β (SMD = 1.45), and IL-6 (SMD = 0.66). Sensitivity analyses confirmed robustness of the pooled results, while publication bias was minimal. According to GRADE, the certainty of evidence was moderate for pain relief and clinical effectiveness and low for other outcomes.</div></div><div><h3>Conclusion</h3><div>Manual therapy demonstrates consistent short-term benefits for patients with LDH across multiple domains, including pain, function, and inflammation. However, since most included trials were conducted in China and were of low-to-moderate methodological quality, the certainty of evidence should be considered moderate to low, and findings should be interpreted with caution. Further high-quality, multi-center international RCTs are warranted to strengthen the evidence base.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103285"},"PeriodicalIF":3.5,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-31DOI: 10.1016/j.ctim.2025.103301
Jinhee Won , Yongwoo Lee
Background
Patellofemoral pain syndrome (PFPS) is a prevalent musculoskeletal condition associated with anterior knee pain and functional limitations. Conventional conservative approaches such as exercise and taping often provide inconsistent relief. Spinal manipulation, a manual therapy technique frequently used in complementary medicine, has demonstrated neurophysiological effects on pain modulation and motor control, but its application in PFPS remains underexplored.
Objective
This randomized controlled trial investigated the effects of lumbar spinal manipulation on pain and quadriceps strength in individuals with PFPS.
Methods
Thirty participants with clinically diagnosed PFPS were randomly allocated to a lumbar spinal manipulation group (n = 15) or a placebo group (n = 15). Interventions were administered twice weekly for four weeks. Outcome measures included pressure pain threshold, knee joint position sense, dynamic balance (Y-balance test), and quadriceps strength, assessed pre- and post-intervention. Paired and independent t-tests were used for within- and between-group comparisons (p < 0.05).
Results
Significant within-group improvements were observed in all outcomes except proprioception at 60° in the manipulation group, and in all but proprioception in the placebo group (p < 0.05). Compared to placebo, lumbar spinal manipulation resulted in significantly greater improvements in pain reduction and quadriceps muscle strength (p < 0.05). No significant between-group differences were noted in proprioception or dynamic balance.
Conclusion
Lumbar spinal manipulation appears to be an effective intervention for alleviating pain and enhancing quadriceps strength in patients with PFPS. Although its impact on proprioception and balance was limited, the findings support its clinical relevance in integrative management strategies for PFPS.
{"title":"Effects of lumbar spinal manipulation on pain and quadriceps strength in patellofemoral pain syndrome: A randomized controlled trial","authors":"Jinhee Won , Yongwoo Lee","doi":"10.1016/j.ctim.2025.103301","DOIUrl":"10.1016/j.ctim.2025.103301","url":null,"abstract":"<div><h3>Background</h3><div>Patellofemoral pain syndrome (PFPS) is a prevalent musculoskeletal condition associated with anterior knee pain and functional limitations. Conventional conservative approaches such as exercise and taping often provide inconsistent relief. Spinal manipulation, a manual therapy technique frequently used in complementary medicine, has demonstrated neurophysiological effects on pain modulation and motor control, but its application in PFPS remains underexplored.</div></div><div><h3>Objective</h3><div>This randomized controlled trial investigated the effects of lumbar spinal manipulation on pain and quadriceps strength in individuals with PFPS.</div></div><div><h3>Methods</h3><div>Thirty participants with clinically diagnosed PFPS were randomly allocated to a lumbar spinal manipulation group (n = 15) or a placebo group (n = 15). Interventions were administered twice weekly for four weeks. Outcome measures included pressure pain threshold, knee joint position sense, dynamic balance (Y-balance test), and quadriceps strength, assessed pre- and post-intervention. Paired and independent t-tests were used for within- and between-group comparisons (p < 0.05).</div></div><div><h3>Results</h3><div>Significant within-group improvements were observed in all outcomes except proprioception at 60° in the manipulation group, and in all but proprioception in the placebo group (p < 0.05). Compared to placebo, lumbar spinal manipulation resulted in significantly greater improvements in pain reduction and quadriceps muscle strength (p < 0.05). No significant between-group differences were noted in proprioception or dynamic balance.</div></div><div><h3>Conclusion</h3><div>Lumbar spinal manipulation appears to be an effective intervention for alleviating pain and enhancing quadriceps strength in patients with PFPS. Although its impact on proprioception and balance was limited, the findings support its clinical relevance in integrative management strategies for PFPS.</div></div><div><h3>Trial Registration</h3><div>Korea Clinical Trial Registry (KCT0010483)</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103301"},"PeriodicalIF":3.5,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The objective of this study is to investigate the efficacy and safety of buccal acupuncture (BA) therapy for pain management through meta-analysis and systematic review.
Methods
A systematic search was conducted across eight databases (PubMed, Web of Science, Embase, Cochrane Library, etc) to identify randomized controlled trials (RCTs) evaluating the efficacy of BA in pain management. The search timeframe encompassed records form each database’s inception through January 25, 2025. The Cochrane Risk of Bias Tool was utilized to assess the methodological quality of the included studies. Meta-analysis was performed using RevMan 5.3 and Stata 15.
Results
A total of 40 RCTs involving 3009 patients were included. Compared with the control intervention, BA improved the total effective rate [RR= 1.19, 95 %CI(1.13, 1.24), p < 0.00001], reduced the incidence of adverse reactions [RR= 0.46, 95 %CI(0.37,0.57), p < 0.00001] and showed a better effect on Visual Analogue Scale (VAS) [SMD= -1.51, 95 %CI(-1.98, −1.04), p < 0.00001] scores. The VAS was used to assess pain intensity, where higher values indicate greater pain severity.
Conclusion
BA demonstrates certain advantages over conventional acupuncture and pharmacotherapy in pain management, with benefits including a lower incidence of adverse reactions and superior pain relief. It may serve as an adjunctive therapy to conventional analgesic treatments in clinical practice. However, further validation through higher-quality, large-sample clinical RCTs is required.
目的：本研究旨在通过荟萃分析和系统评价，探讨口腔针灸治疗疼痛的疗效和安全性。方法：系统检索PubMed、Web of Science、Embase、Cochrane Library等8个数据库，筛选评估BA治疗疼痛疗效的随机对照试验（rct）。搜索时间范围包括从每个数据库开始到2025年1月25日的记录。采用Cochrane偏倚风险工具评估纳入研究的方法学质量。采用RevMan 5.3和Stata 15进行meta分析。结果：共纳入40项rct，涉及3,009例患者。与对照组干预相比，BA提高了总有效率[RR=1.19, 95%CI(1.13, 1.24)]。结论：BA在疼痛管理方面比传统针灸和药物治疗有一定优势，其不良反应发生率更低，疼痛缓解效果更好。在临床实践中可作为常规镇痛治疗的辅助治疗。然而，需要通过更高质量的大样本临床随机对照试验进一步验证。
{"title":"Efficacy and safety of buccal acupuncture for pain management: A systematic review and meta-analysis","authors":"Liyang Guo , Tianrui Jia , Yuhan Yang , Huagui Feng , Ping Jiang","doi":"10.1016/j.ctim.2025.103297","DOIUrl":"10.1016/j.ctim.2025.103297","url":null,"abstract":"<div><h3>Objective</h3><div>The objective of this study is to investigate the efficacy and safety of buccal acupuncture (BA) therapy for pain management through meta-analysis and systematic review.</div></div><div><h3>Methods</h3><div>A systematic search was conducted across eight databases (PubMed, Web of Science, Embase, Cochrane Library, etc) to identify randomized controlled trials (RCTs) evaluating the efficacy of BA in pain management. The search timeframe encompassed records form each database’s inception through January 25, 2025. The Cochrane Risk of Bias Tool was utilized to assess the methodological quality of the included studies. Meta-analysis was performed using RevMan 5.3 and Stata 15.</div></div><div><h3>Results</h3><div>A total of 40 RCTs involving 3009 patients were included. Compared with the control intervention, BA improved the total effective rate [RR= 1.19, 95 %CI(1.13, 1.24), p < 0.00001], reduced the incidence of adverse reactions [RR= 0.46, 95 %CI(0.37,0.57), p < 0.00001] and showed a better effect on Visual Analogue Scale (VAS) [SMD= -1.51, 95 %CI(-1.98, −1.04), p < 0.00001] scores. The VAS was used to assess pain intensity, where higher values indicate greater pain severity.</div></div><div><h3>Conclusion</h3><div>BA demonstrates certain advantages over conventional acupuncture and pharmacotherapy in pain management, with benefits including a lower incidence of adverse reactions and superior pain relief. It may serve as an adjunctive therapy to conventional analgesic treatments in clinical practice. However, further validation through higher-quality, large-sample clinical RCTs is required.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103297"},"PeriodicalIF":3.5,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-30DOI: 10.1016/j.ctim.2025.103281
Josiane Bissonnette , Andréanne Côté , Peter-Gens Desameau , Mariève Cossette , Anne Marie Pinard , Caroline Arbour , Gabrielle Fortin , David Ogez , Pierre Rainville
Objectives
To evaluate the preliminary effectiveness of a personalized intervention integrating pre-recorded hypnosis and/or music in palliative and end-of-life care, and explore patient preferences and experiences.
Methods
Forty patients receiving palliative and end-of-life care at home were recruited and randomly assigned to the experimental group or the control/delayed intervention group. Two intervention sessions were conducted within one week, featuring the following modalities tailored to patient preferences: pre-recorded music, hypnosis, or a combination of music and hypnosis. Participants provided self-ratings of their symptoms and distress at predetermined time points using the Edmonton Symptom Assessment Scale and the Distress Thermometer. We used a mixed-effects model to address the quantitative objectives, and we conducted a content analysis to meet the qualitative objectives.
Results
The intervention program significantly reduced participants’ distress, showing a medium effect size when comparing the intervention sessions to the control sessions. We also found a medium effect size for improved well-being between groups. Intervention modality did not appear to affect the responses. Participants reported calmness and well-being. The voluntary use of these interventions post-experiment emphasizes their relevance for palliative and end-of-life care. The qualitative findings were consistent with the quantitative results, and revealed additional potential uses and ways to improve the intervention.
Conclusion
The personalized pre-recorded music and hypnosis interventions appear to be effective in reducing distress and show great potential for enhancing the overall well-being of individuals in palliative and end-of-life care. Further studies are needed to determine how these findings can be applied to a broader population.
{"title":"Personalized music and hypnosis interventions in palliative and end-of-life care at home: A randomized controlled pilot study","authors":"Josiane Bissonnette , Andréanne Côté , Peter-Gens Desameau , Mariève Cossette , Anne Marie Pinard , Caroline Arbour , Gabrielle Fortin , David Ogez , Pierre Rainville","doi":"10.1016/j.ctim.2025.103281","DOIUrl":"10.1016/j.ctim.2025.103281","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the preliminary effectiveness of a personalized intervention integrating pre-recorded hypnosis and/or music in palliative and end-of-life care, and explore patient preferences and experiences.</div></div><div><h3>Methods</h3><div>Forty patients receiving palliative and end-of-life care at home were recruited and randomly assigned to the experimental group or the control/delayed intervention group. Two intervention sessions were conducted within one week, featuring the following modalities tailored to patient preferences: pre-recorded music, hypnosis, or a combination of music and hypnosis. Participants provided self-ratings of their symptoms and distress at predetermined time points using the Edmonton Symptom Assessment Scale and the Distress Thermometer. We used a mixed-effects model to address the quantitative objectives, and we conducted a content analysis to meet the qualitative objectives.</div></div><div><h3>Results</h3><div>The intervention program significantly reduced participants’ distress, showing a medium effect size when comparing the intervention sessions to the control sessions. We also found a medium effect size for improved well-being between groups. Intervention modality did not appear to affect the responses. Participants reported calmness and well-being. The voluntary use of these interventions post-experiment emphasizes their relevance for palliative and end-of-life care. The qualitative findings were consistent with the quantitative results, and revealed additional potential uses and ways to improve the intervention.</div></div><div><h3>Conclusion</h3><div>The personalized pre-recorded music and hypnosis interventions appear to be effective in reducing distress and show great potential for enhancing the overall well-being of individuals in palliative and end-of-life care. Further studies are needed to determine how these findings can be applied to a broader population.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103281"},"PeriodicalIF":3.5,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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