Pub Date : 2023-12-27DOI: 10.51910/ijhdr.v22i2.1348
Francisco Eizayaga, Adalberto von Ancken, Adriana Ceballos, Veronica Bergstein, Carolina Aguilar, Marcela Junin, Bruna Nambu, L. Bonamin
Introduction: Homeopathy is being questioned mostly in developed countries, despite the growing body of basic and clinical research with positive results. Even though many meta-analyses show positive findings, there is an urge for large clinical studies to improve the perception that there is an effect. To test the awareness of homeopaths in the research needs, a survey was developed asking about usefulness, and everyday use of research findings. Methods: The respondents were identified by the degree of academic study, age, experience, kind of practice, region of practice, and scientific background. To understand the predominant thoughts, questions were asked to define whether Homeopathy should be considered and studied as science if the homeopath regularly reads scientific papers, and of what kind. Also, the definition of which kind of literature contributes the most to ameliorating the quality of medical attention, the usefulness of basic and clinical research, the source of the research budget, and the priorities for future research. The forms were created in Spanish and Portuguese, and distributed by email, mostly in South America during July and part of August 2023. Results: A total of 463 responses were analyzed. More than 90% of the respondents were practicing homeopaths and 209 were MDs, 64% participated in a scientific study in the past. When asked about developing homeopathy, 50% preferred clinical research, 19% meta-analysis, 11% basic research, 11% HPT and 6% clinical verification. Funding should be provided by public institutions, Universities, and pharmaceutical companies. When asked about prescribing 76% relied on experience transmitted by masters, 66% on their own experience, and 48% on clinical research. Clinical research was found useful in 88% of the sample. There was no clear response when asked about sources for improving clinical practice. Conclusion: Homeopaths are informed about scientific research but have no clear perception of how it may improve clinical practice.
{"title":"Usefulness of scientific research in Homeopathy","authors":"Francisco Eizayaga, Adalberto von Ancken, Adriana Ceballos, Veronica Bergstein, Carolina Aguilar, Marcela Junin, Bruna Nambu, L. Bonamin","doi":"10.51910/ijhdr.v22i2.1348","DOIUrl":"https://doi.org/10.51910/ijhdr.v22i2.1348","url":null,"abstract":"Introduction: Homeopathy is being questioned mostly in developed countries, despite the growing body of basic and clinical research with positive results. Even though many meta-analyses show positive findings, there is an urge for large clinical studies to improve the perception that there is an effect. To test the awareness of homeopaths in the research needs, a survey was developed asking about usefulness, and everyday use of research findings. Methods: The respondents were identified by the degree of academic study, age, experience, kind of practice, region of practice, and scientific background. To understand the predominant thoughts, questions were asked to define whether Homeopathy should be considered and studied as science if the homeopath regularly reads scientific papers, and of what kind. Also, the definition of which kind of literature contributes the most to ameliorating the quality of medical attention, the usefulness of basic and clinical research, the source of the research budget, and the priorities for future research. The forms were created in Spanish and Portuguese, and distributed by email, mostly in South America during July and part of August 2023. Results: A total of 463 responses were analyzed. More than 90% of the respondents were practicing homeopaths and 209 were MDs, 64% participated in a scientific study in the past. When asked about developing homeopathy, 50% preferred clinical research, 19% meta-analysis, 11% basic research, 11% HPT and 6% clinical verification. Funding should be provided by public institutions, Universities, and pharmaceutical companies. When asked about prescribing 76% relied on experience transmitted by masters, 66% on their own experience, and 48% on clinical research. Clinical research was found useful in 88% of the sample. There was no clear response when asked about sources for improving clinical practice. Conclusion: Homeopaths are informed about scientific research but have no clear perception of how it may improve clinical practice.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-21DOI: 10.51910/ijhdr.v22icf.1313
Dr.Parth Aphale, Shashank Dokania, Dr Dharmendra Sharma
Introduction: Leading the world towards disability and prolonged sufferings, osteoarthritis (OA) multiplies the number of cases to about 113.25% over a decade. Healthcare services of developing nations are knocked down with flooding patients only to understand that the patient has to undergo palliative treatment for his entire life. Homoeopathic principles are way beyond palliation, a much reliable approach on the lines of minimum doses in treating OA. Objective: This article reviews the variable conditions associated with OA and the adverse effects these conditions can have on patients. 7 studies have been reviewed in this article and the effects of Homoeopathic attenuations on OA patients have been studied. Methods: Parameters including oxidant stress, physiotherapy, analog scales, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, erythrocyte lipid peroxidation (LP) and Superoxide dismutase (SOD) levels and Activities of Daily living (ADL) have been compared and results have been outlined before and after treatment with homoeopathic ultra high dilutions. Results: Clinical analysis and statistical data verifies improved WOMAC score, reduction in stiffness and pain in the joints, reduction in marginal deposition of osteocytes, erythrocyte LP and SOD levels post treatment with homoeopathic remedies.
导言：骨关节炎（OA）是导致世界残疾和长期痛苦的疾病，在过去十年中，其发病率成倍增长，达到约 113.25%。发展中国家的医疗服务被大量涌入的患者击倒，而患者却不得不终生接受姑息治疗。同种疗法的原理远远超出了姑息治疗的范畴，它是一种治疗 OA 的可靠方法，采用的是最小剂量疗法。目的：本文回顾了与 OA 相关的各种情况，以及这些情况可能对患者产生的不良影响。本文回顾了 7 项研究，并研究了同种异体疗法对 OA 患者的影响。方法：比较了氧化应激、物理治疗、模拟量表、西安大略和麦克马斯特大学骨关节炎指数（WOMAC）评分、红细胞脂质过氧化物（LP）和超氧化物歧化酶（SOD）水平以及日常生活活动（ADL）等参数，并概述了使用同种疗法超高稀释液治疗前后的结果。结果：临床分析和统计数据证实，使用同种疗法治疗后，WOMAC 评分提高，关节僵硬和疼痛减轻，骨细胞边缘沉积减少，红细胞 LP 和 SOD 水平降低。
{"title":"Revisiting the Homoeopathic approach to Osteoarthritis- A Review","authors":"Dr.Parth Aphale, Shashank Dokania, Dr Dharmendra Sharma","doi":"10.51910/ijhdr.v22icf.1313","DOIUrl":"https://doi.org/10.51910/ijhdr.v22icf.1313","url":null,"abstract":"Introduction: Leading the world towards disability and prolonged sufferings, osteoarthritis (OA) multiplies the number of cases to about 113.25% over a decade. Healthcare services of developing nations are knocked down with flooding patients only to understand that the patient has to undergo palliative treatment for his entire life. Homoeopathic principles are way beyond palliation, a much reliable approach on the lines of minimum doses in treating OA. Objective: This article reviews the variable conditions associated with OA and the adverse effects these conditions can have on patients. 7 studies have been reviewed in this article and the effects of Homoeopathic attenuations on OA patients have been studied. Methods: Parameters including oxidant stress, physiotherapy, analog scales, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, erythrocyte lipid peroxidation (LP) and Superoxide dismutase (SOD) levels and Activities of Daily living (ADL) have been compared and results have been outlined before and after treatment with homoeopathic ultra high dilutions. Results: Clinical analysis and statistical data verifies improved WOMAC score, reduction in stiffness and pain in the joints, reduction in marginal deposition of osteocytes, erythrocyte LP and SOD levels post treatment with homoeopathic remedies. \u0000 \u0000 \u0000 \u0000 ","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"44 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138951830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.51910/ijhdr.v22i2.1333
Silvia Helena Fernandes Alves, C. Coelho, Adalberto von Ancken, Cintia Regina Fabbrini
Snakebite accidents are very common nearby forest areas. The majority of these incidents are caused by snakes of the genus Bothrops, which comprises over 45 species distributed in Central and South America. These snakes usually hunt small mammals and lizards at dusk. Snakebites from this genus generally occur in the head, limbs, and neck regions. Bothrops snakes are considered aggressive animals, characterized by inverted "V" markings along their bodies, triangular heads, smooth tails, and length ranging from 0.5m to 2m. They exhibit color variations of brown, green, and gray. Bothrops venom has necrotic, coagulating, vasculotoxic, and nephrotoxic effects, which can cause extensive necrosis at the bite site, tissue loss, and limb dysfunction, sometimes resulting in amputation. The bitten animal may experience prostration, tachypnea, localized edema and pain, petechiae, hemorrhages, and extensive necrotic areas. Hematuria, hypotension, pulmonary edema, and even death, as well as various laboratory abnormalities, may also occur. The case reported herein was attended at a veterinary clinic in Campos Altos, Minas Gerais, Brazil. It involved a mixed-breed female dog, 3 years old, weighing 4.5 kg, which had been bitten by a Bothrops snake approximately 90 minutes before. The animal presented edema and pain at the site of the bite (pelvic limb), as well as tachycardia. At once, it was administered intravenous polyvalent antiophidic serum, dexamethasone, serum, furosemide, tramadol, and ceftriaxone (antibiotic). Local treatment included corticosteroid and antibiotic ointment dressings. The animal remained stable, but after 24 hours, an extensive area with edema, hematoma, bleeding, and early necrosis at the bite site was observed, worsening with each passing hour. After 48 hours, therapy with Bothrops CH6 (5 globules every 8 hours) was initiated to reduce local effects (edema, hemorrhage, and necrosis). The animal showed rapid improvement in the appearance of the lesion, and after 5 days of treatment, there was no longer edema or bleeding, only a circumscribed cutaneous injury, which was managed with local dressings (cleaning and healing ointment). The animal recovered well without any sequelae.
{"title":"Homeopathic Treatment of snakebite in dog – case report","authors":"Silvia Helena Fernandes Alves, C. Coelho, Adalberto von Ancken, Cintia Regina Fabbrini","doi":"10.51910/ijhdr.v22i2.1333","DOIUrl":"https://doi.org/10.51910/ijhdr.v22i2.1333","url":null,"abstract":"Snakebite accidents are very common nearby forest areas. The majority of these incidents are caused by snakes of the genus Bothrops, which comprises over 45 species distributed in Central and South America. These snakes usually hunt small mammals and lizards at dusk. Snakebites from this genus generally occur in the head, limbs, and neck regions. Bothrops snakes are considered aggressive animals, characterized by inverted \"V\" markings along their bodies, triangular heads, smooth tails, and length ranging from 0.5m to 2m. They exhibit color variations of brown, green, and gray. Bothrops venom has necrotic, coagulating, vasculotoxic, and nephrotoxic effects, which can cause extensive necrosis at the bite site, tissue loss, and limb dysfunction, sometimes resulting in amputation. The bitten animal may experience prostration, tachypnea, localized edema and pain, petechiae, hemorrhages, and extensive necrotic areas. Hematuria, hypotension, pulmonary edema, and even death, as well as various laboratory abnormalities, may also occur. The case reported herein was attended at a veterinary clinic in Campos Altos, Minas Gerais, Brazil. It involved a mixed-breed female dog, 3 years old, weighing 4.5 kg, which had been bitten by a Bothrops snake approximately 90 minutes before. The animal presented edema and pain at the site of the bite (pelvic limb), as well as tachycardia. At once, it was administered intravenous polyvalent antiophidic serum, dexamethasone, serum, furosemide, tramadol, and ceftriaxone (antibiotic). Local treatment included corticosteroid and antibiotic ointment dressings. The animal remained stable, but after 24 hours, an extensive area with edema, hematoma, bleeding, and early necrosis at the bite site was observed, worsening with each passing hour. After 48 hours, therapy with Bothrops CH6 (5 globules every 8 hours) was initiated to reduce local effects (edema, hemorrhage, and necrosis). The animal showed rapid improvement in the appearance of the lesion, and after 5 days of treatment, there was no longer edema or bleeding, only a circumscribed cutaneous injury, which was managed with local dressings (cleaning and healing ointment). The animal recovered well without any sequelae.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"15 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139168468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.51910/ijhdr.v22i2.1339
Dr Sanjib Chattopadhyay
Abstract: Background: Some workers postulated that homeopathic medicines have got some alterations of hydrogen bonded network in water molecules for their activity, but according to others the original drug molecule remains present as nanoparticles. Objective: To prove experimentally whether traces of medicine molecules are present in ultra high dilution and determine its apparent cause. Materials and Methods: To detect existence of Copper ion in 5 ultra high dilutions (6c, 30c, 200c, 1000c and 10000c) in Cuprum metallicum were subjected to Atomic Absorption Spectrophotometry. An experiment was also set up to determine how one can obtain trails of original molecules in highly diluted solutions beyond Avogadro’s limit where a solution of copper sulfate was successively diluted decimally in three different ways: NSW (Non-”Succussed” Water), SW(“Succussed” Water), SWE (“Succussed” Water with 50% ethanol) and was studied by UV-Vis Spectrophotometer. Result: Existence of a Copper ion was found asymptotically decreasing through all the five dilutions. In the second experiment it was observed that in case of NSW solution the Optical Density (OD) reaches to non-detectable (ND) range earlier, but for SW and SWE later. Conclusion: Some sorts of non-homogeneity established in “succussed” alcoholic dilutions due to fall of dielectric constant. With the increase of dilution more proportion of solute molecules in the form of nanoparticles covered by solvent layers become transferred to the next serial dilution. Drugs, tightly packed by ethanol (‘nanoparticles’) easily enter inside cell, bring symptoms to the “provers” and cure patients as well when applied in minute dose.
{"title":"Existence of original drug molecules in ultra high dilutions","authors":"Dr Sanjib Chattopadhyay","doi":"10.51910/ijhdr.v22i2.1339","DOIUrl":"https://doi.org/10.51910/ijhdr.v22i2.1339","url":null,"abstract":"Abstract: Background: Some workers postulated that homeopathic medicines have got some alterations of hydrogen bonded network in water molecules for their activity, but according to others the original drug molecule remains present as nanoparticles. Objective: To prove experimentally whether traces of medicine molecules are present in ultra high dilution and determine its apparent cause. Materials and Methods: To detect existence of Copper ion in 5 ultra high dilutions (6c, 30c, 200c, 1000c and 10000c) in Cuprum metallicum were subjected to Atomic Absorption Spectrophotometry. An experiment was also set up to determine how one can obtain trails of original molecules in highly diluted solutions beyond Avogadro’s limit where a solution of copper sulfate was successively diluted decimally in three different ways: NSW (Non-”Succussed” Water), SW(“Succussed” Water), SWE (“Succussed” Water with 50% ethanol) and was studied by UV-Vis Spectrophotometer. Result: Existence of a Copper ion was found asymptotically decreasing through all the five dilutions. In the second experiment it was observed that in case of NSW solution the Optical Density (OD) reaches to non-detectable (ND) range earlier, but for SW and SWE later. Conclusion: Some sorts of non-homogeneity established in “succussed” alcoholic dilutions due to fall of dielectric constant. With the increase of dilution more proportion of solute molecules in the form of nanoparticles covered by solvent layers become transferred to the next serial dilution. Drugs, tightly packed by ethanol (‘nanoparticles’) easily enter inside cell, bring symptoms to the “provers” and cure patients as well when applied in minute dose.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"18 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139169489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.51910/ijhdr.v22i2.1350
Maria Luiza de Sousa Barbosa, C. de Paula Coelho, Adalberto von Ancken
Acquired megaesophagus is a disease characterized by esophageal dilation resulting from reduced or absent esophageal motility and may be caused by myasthenia gravis. Treatment for the diagnosis of megaesophagus is palliative, but the bronchopneumopathy condition was quickly reversed with the use of Baryta Carbonica, demonstrating the effectiveness of homeopathic therapy.
{"title":"Baryta Carbonica homeopathic therapy for bronchopneumonia in a dog with megaesophagus","authors":"Maria Luiza de Sousa Barbosa, C. de Paula Coelho, Adalberto von Ancken","doi":"10.51910/ijhdr.v22i2.1350","DOIUrl":"https://doi.org/10.51910/ijhdr.v22i2.1350","url":null,"abstract":"Acquired megaesophagus is a disease characterized by esophageal dilation resulting from reduced or absent esophageal motility and may be caused by myasthenia gravis. Treatment for the diagnosis of megaesophagus is palliative, but the bronchopneumopathy condition was quickly reversed with the use of Baryta Carbonica, demonstrating the effectiveness of homeopathic therapy.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"104 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139171097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.51910/ijhdr.v22i2.1299
L. Mourão, V. Motta, Antônio Canabarro, D. Cataldo, R. Nardy
Bruxism is described as an orofacial parafunction that affects children and adults characterized by the habit of grinding or clench our teeth, with complex and multifactorial etiology, as well as your diagnosis and control. Can be considered centric when the habit of squeezing the teeth occurs semi-conscious and action is called day or Vigil (BV) and eccentric when the gnashing of teeth and unconscious action called Nightcrawler or (BS). Like homeopathy (H) aims to restore the balance of the vital energy of the patient allowing the motion of the body's healing the objective of this research was to evaluate the efficacy of homeopathic medicines (Cimex lectularius and Matricaria chamomilla), concurrent with the conventional therapy for an alternative in the control of bruxism. Material and methods the sample was constituted of 60 patients with different social backgrounds, of both genders aged from 18 to 60 years who responded to questionnaires and passed through oral clinical examination with positive response to bruxism. Were divided into test group (GT) 30 subjects treated with interoclusais acrylic plates associated with homeopathic medicines and the control group (GC) 30 individuals have used interoclusais plates more placebo ( homeopathic medicines without the active) for a total period of 06 (six) months, were evaluated monthly for checking the reduction of signs and symptoms of bruxism. Was concluded the effectiveness of homeopathic therapy as an adjunct to conventional treatment with interoclusais board, easing pain disorders and dental damage caused by bruxism.
{"title":"Complementary homeopathic therapy in the treatment of sleep bruxism","authors":"L. Mourão, V. Motta, Antônio Canabarro, D. Cataldo, R. Nardy","doi":"10.51910/ijhdr.v22i2.1299","DOIUrl":"https://doi.org/10.51910/ijhdr.v22i2.1299","url":null,"abstract":"Bruxism is described as an orofacial parafunction that affects children and adults characterized by the habit of grinding or clench our teeth, with complex and multifactorial etiology, as well as your diagnosis and control. Can be considered centric when the habit of squeezing the teeth occurs semi-conscious and action is called day or Vigil (BV) and eccentric when the gnashing of teeth and unconscious action called Nightcrawler or (BS). Like homeopathy (H) aims to restore the balance of the vital energy of the patient allowing the motion of the body's healing the objective of this research was to evaluate the efficacy of homeopathic medicines (Cimex lectularius and Matricaria chamomilla), concurrent with the conventional therapy for an alternative in the control of bruxism. Material and methods the sample was constituted of 60 patients with different social backgrounds, of both genders aged from 18 to 60 years who responded to questionnaires and passed through oral clinical examination with positive response to bruxism. Were divided into test group (GT) 30 subjects treated with interoclusais acrylic plates associated with homeopathic medicines and the control group (GC) 30 individuals have used interoclusais plates more placebo ( homeopathic medicines without the active) for a total period of 06 (six) months, were evaluated monthly for checking the reduction of signs and symptoms of bruxism. Was concluded the effectiveness of homeopathic therapy as an adjunct to conventional treatment with interoclusais board, easing pain disorders and dental damage caused by bruxism.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"163 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139169748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.51910/ijhdr.v22i2.1303
Nathalia Salles Scortegagna de Medeiros, S. Frana, Mônica Filomena Souza, Ivana Barbosa Suffredini, Steven J. Cartwright, Leoni Villano Bonamin
Introduction: Solvatochromic dyes seem to act as physicochemical markers of homeopathic medicines. Herein, methylene violet was selected from a pilot study to identify the homeopathic complex (Arnica montana 30 cH, Phosphorus 30 cH, Arsenicum album 30 cH, Ignatia amara 30 cH, and Staphysagria 30 cH) designed to be used in the Nascentes do Rio Taquari at IMASUL Environment Institute of Mato Grosso do Sul = Brazil) request, intending to facilitate the ecosystem's bioresilience after being burned down in September 2020. Brazil has no legal restrictions on using dynamized products in the natural environment. Methods: the complex was prepared in ethanol 30% and soaked in biodegradable inert gel (calcium acetate) set at nine strategic points in the park. Water samples were harvested from each point at different times, before and after the insertion of the devices. Then, they were filtered through a 0.22 Micra mesh filter for sterilization and frozen. For analysis, 1 cH potencies of each thawed water sample were prepared using 30% ethanol as solvent. The ready-made samples were submitted (or not) to a magnetic field (2400G average) for 15 minutes, whose flow was generated from a neodymium magnet (5.08 cm x 5.08 cm x 12.7 mm) isolated from any other electromagnetic influence. Soon, after magnetizing, samples were added 1:60 into methylene violet dye, prepared in water pH=4.0, in microplates, and read in an ELISA reader at a wavelength of 598 nm. Controls were 30% ethanol, Ethylicum 1cH, and magnetized water. Statistical analysis was performed by the Shapiro-Wilk normality test and parametric or non-parametric ANOVA, with p≤0.05 considered significant. Results: Significant differences between the homeopathic complex and controls were seen when magnetized samples (p=0.0045). Instead, only one sample (point 2) without magnetization showed statistical significance (p≤0.05) from the controls. Conclusion: using solvatochromic dyes can be considered a good method to track the presence of the homeopathic complex in spring water, and the magnetization of samples seems to be an efficient tool to improve the method’s sensitivity.
导言：溶变色染料似乎是顺势疗法药物的理化标记。在此，亚甲基紫被选作一项试点研究的对象，用于识别顺势疗法复方（山金车30 cH、磷30 cH、砒霜30 cH、枳实30 cH和葡萄30 cH），该复方将用于南马托格罗索（Mato Grosso do Sul = Brazil）IMASUL环境研究所的Nascentes do Rio Taquari，以促进生态系统在2020年9月被烧毁后的生物恢复能力。巴西对在自然环境中使用动力产品没有法律限制。方法：用 30% 的乙醇制备复合物，并将其浸泡在可生物降解的惰性凝胶（醋酸钙）中，设置在公园的九个战略点上。在插入装置前后的不同时间，从每个点采集水样。然后，用 0.22 Micra 网眼过滤器进行过滤消毒并冷冻。分析时，使用 30% 的乙醇作为溶剂，对每个解冻的水样制备 1 cH 的效价。将制备好的样品置于（或不置于）磁场（平均 2400G）中 15 分钟，磁场由钕磁铁（5.08 厘米 x 5.08 厘米 x 12.7 毫米）产生，与其他电磁影响隔绝。磁化后不久，将样品按 1:60 的比例加入微孔板中的亚甲基紫染料（在 pH=4.0 的水中制备），并在波长为 598 纳米的 ELISA 阅读器中读取。对照组为 30% 乙醇、乙醇 1cH 和磁化水。统计分析采用 Shapiro-Wilk 正态性检验和参数或非参数方差分析，以 p≤0.05 为显著。结果磁化样本时，顺势疗法复方与对照组之间存在显著差异（p=0.0045）。相反，只有一个未磁化的样本（点 2）与对照组相比具有统计学意义（p≤0.05）。结论：使用溶解变色染料可被视为跟踪泉水中顺势疗法复合物存在情况的好方法，而样品磁化似乎是提高该方法灵敏度的有效工具。
{"title":"Solvatochromic dyes as a tool for tracking homeopathic complex activity in water reservoirs of a spring park in Brazil: Physicochemical implications","authors":"Nathalia Salles Scortegagna de Medeiros, S. Frana, Mônica Filomena Souza, Ivana Barbosa Suffredini, Steven J. Cartwright, Leoni Villano Bonamin","doi":"10.51910/ijhdr.v22i2.1303","DOIUrl":"https://doi.org/10.51910/ijhdr.v22i2.1303","url":null,"abstract":"Introduction: Solvatochromic dyes seem to act as physicochemical markers of homeopathic medicines. Herein, methylene violet was selected from a pilot study to identify the homeopathic complex (Arnica montana 30 cH, Phosphorus 30 cH, Arsenicum album 30 cH, Ignatia amara 30 cH, and Staphysagria 30 cH) designed to be used in the Nascentes do Rio Taquari at IMASUL Environment Institute of Mato Grosso do Sul = Brazil) request, intending to facilitate the ecosystem's bioresilience after being burned down in September 2020. Brazil has no legal restrictions on using dynamized products in the natural environment. Methods: the complex was prepared in ethanol 30% and soaked in biodegradable inert gel (calcium acetate) set at nine strategic points in the park. Water samples were harvested from each point at different times, before and after the insertion of the devices. Then, they were filtered through a 0.22 Micra mesh filter for sterilization and frozen. For analysis, 1 cH potencies of each thawed water sample were prepared using 30% ethanol as solvent. The ready-made samples were submitted (or not) to a magnetic field (2400G average) for 15 minutes, whose flow was generated from a neodymium magnet (5.08 cm x 5.08 cm x 12.7 mm) isolated from any other electromagnetic influence. Soon, after magnetizing, samples were added 1:60 into methylene violet dye, prepared in water pH=4.0, in microplates, and read in an ELISA reader at a wavelength of 598 nm. Controls were 30% ethanol, Ethylicum 1cH, and magnetized water. Statistical analysis was performed by the Shapiro-Wilk normality test and parametric or non-parametric ANOVA, with p≤0.05 considered significant. Results: Significant differences between the homeopathic complex and controls were seen when magnetized samples (p=0.0045). Instead, only one sample (point 2) without magnetization showed statistical significance (p≤0.05) from the controls. Conclusion: using solvatochromic dyes can be considered a good method to track the presence of the homeopathic complex in spring water, and the magnetization of samples seems to be an efficient tool to improve the method’s sensitivity.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"240 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139170146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.51910/ijhdr.v22i2.1395
Alastair C. Gray, Denise Straiges
Background: This presentation provides an overview of the research work at HOHM Foundation and the most inspiring results from the last 5 years, highlighting important findings from our numerous published and ongoing research projects. Methods: HOHM Foundation officially launched its Office of Research (HOHM Research) in 2017 in keeping with the mission to enrich and support homeopathy, and an overarching aim to build infrastructure whereby rigorous outcomes-based research supports the deepening and expansion of the discipline of Homeopathy. Results: Recent peer-reviewed publications include five papers on the education of complementary and integrative medicine practitioners, as well as three observational case series of selected COVID-19 cases from the HHN Clinic. Additional papers based on the 5000+ dataset of acute cases from the Homeopathy Help Network (HHN) clinic are currently being prepared. From the Practitioner Generated Research Network (PGRN) – an organization promoting practice-based, patient-focused, practitioner-generated research that potentizes the profession of homeopathy and expands it into the larger scientific and integrative medical communities - a paper exploring attitudes to and uptake of repertory software in homeopathy clinical practice was published in Homeopathy in 2023. Current papers from the PGRN in the publication phase include an observational clinical case series using MYMOP 2017-20, and an observational clinical case series using MYCaW 2020-22 data, both collected from clients who attended the Academy of Homeopathy Education (AHE) chronic clinic. Other current research work focusses on artificial intelligence in Homeopathy, on the characteristics, demographics and perceptions of users of homeopathy in the US, the 2022 North American homeopathy education surveys, the 2023 North American workforce survey, and a clinical trial on Homeopathy in the management of Silicosis taking place in Brazil. Discussion: HOHM Research produces robust, relevant publications, and bring awareness of the effectiveness of homeopathy through real-world, outcomes-based research, focusing on clinical, historical, and educational research outputs.
{"title":"Findings from Clinical, Historical, and Educational Research Conducted at the HOHM Foundation Office of Research","authors":"Alastair C. Gray, Denise Straiges","doi":"10.51910/ijhdr.v22i2.1395","DOIUrl":"https://doi.org/10.51910/ijhdr.v22i2.1395","url":null,"abstract":"Background: This presentation provides an overview of the research work at HOHM Foundation and the most inspiring results from the last 5 years, highlighting important findings from our numerous published and ongoing research projects. Methods: HOHM Foundation officially launched its Office of Research (HOHM Research) in 2017 in keeping with the mission to enrich and support homeopathy, and an overarching aim to build infrastructure whereby rigorous outcomes-based research supports the deepening and expansion of the discipline of Homeopathy. Results: Recent peer-reviewed publications include five papers on the education of complementary and integrative medicine practitioners, as well as three observational case series of selected COVID-19 cases from the HHN Clinic. Additional papers based on the 5000+ dataset of acute cases from the Homeopathy Help Network (HHN) clinic are currently being prepared. From the Practitioner Generated Research Network (PGRN) – an organization promoting practice-based, patient-focused, practitioner-generated research that potentizes the profession of homeopathy and expands it into the larger scientific and integrative medical communities - a paper exploring attitudes to and uptake of repertory software in homeopathy clinical practice was published in Homeopathy in 2023. Current papers from the PGRN in the publication phase include an observational clinical case series using MYMOP 2017-20, and an observational clinical case series using MYCaW 2020-22 data, both collected from clients who attended the Academy of Homeopathy Education (AHE) chronic clinic. Other current research work focusses on artificial intelligence in Homeopathy, on the characteristics, demographics and perceptions of users of homeopathy in the US, the 2022 North American homeopathy education surveys, the 2023 North American workforce survey, and a clinical trial on Homeopathy in the management of Silicosis taking place in Brazil. Discussion: HOHM Research produces robust, relevant publications, and bring awareness of the effectiveness of homeopathy through real-world, outcomes-based research, focusing on clinical, historical, and educational research outputs.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"45 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139171079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.51910/ijhdr.v22i2.1366
C. Coelho, Thaís Sanches, Mayra Frediani Frediani, Talita Risério, Francisco Conde, Sonia Pinheiro
The red howler monkey (Alouatta guariba) is an endemic primate of the Atlantic Forest, classified as vulnerable. They're susceptible to giardiasis, impacting human health and Alouatta genus conservation. Studies report parasite occurrence in wild and captive individuals. While asymptomatic infections are common in captivity, immunosuppression can lead to severe cases. São Paulo's Wildlife Division maintains a large captive population. To assess Giardia duodenalis presence, fecal samples were collected from 43 individuals in 17 enclosures over three days, totaling 153 examinations. Animals were asymptomatic, with some groups showing loose stools. Two processing methods (direct and Sheather) were used, followed by quantitative evaluation based on cysts per slide. Only one enclosure tested negative; others were rare (4), slight (8), or moderate (4). Despite being asymptomatic, treatment was chosen to prevent positive animals from spreading infection. Allopathic treatment was impractical due to enclosure size; homeopathic Giardia 30cH nosode was given via water and food for 15 days to 16 positive enclosures. Afterward, 144 fecal samples were reanalyzed over three days. Seven enclosures were negative, 8 were rare, one was slight, none were moderate. All had firm feces. Kruskal-Wallis test confirmed significant treatment (p=0.004). Giardia 30cH nosode reduced parasitism, environmental contamination, with easy administration and no stress/adverse effects.
{"title":"Giardia nosode 30cH in the treatment of howler monkey (Alouatta guariba) with giardiasis in captivity in Brazil","authors":"C. Coelho, Thaís Sanches, Mayra Frediani Frediani, Talita Risério, Francisco Conde, Sonia Pinheiro","doi":"10.51910/ijhdr.v22i2.1366","DOIUrl":"https://doi.org/10.51910/ijhdr.v22i2.1366","url":null,"abstract":"The red howler monkey (Alouatta guariba) is an endemic primate of the Atlantic Forest, classified as vulnerable. They're susceptible to giardiasis, impacting human health and Alouatta genus conservation. Studies report parasite occurrence in wild and captive individuals. While asymptomatic infections are common in captivity, immunosuppression can lead to severe cases. São Paulo's Wildlife Division maintains a large captive population. To assess Giardia duodenalis presence, fecal samples were collected from 43 individuals in 17 enclosures over three days, totaling 153 examinations. Animals were asymptomatic, with some groups showing loose stools. Two processing methods (direct and Sheather) were used, followed by quantitative evaluation based on cysts per slide. Only one enclosure tested negative; others were rare (4), slight (8), or moderate (4). Despite being asymptomatic, treatment was chosen to prevent positive animals from spreading infection. Allopathic treatment was impractical due to enclosure size; homeopathic Giardia 30cH nosode was given via water and food for 15 days to 16 positive enclosures. Afterward, 144 fecal samples were reanalyzed over three days. Seven enclosures were negative, 8 were rare, one was slight, none were moderate. All had firm feces. Kruskal-Wallis test confirmed significant treatment (p=0.004). Giardia 30cH nosode reduced parasitism, environmental contamination, with easy administration and no stress/adverse effects.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"15 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139168449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.51910/ijhdr.v22i2.1361
Olga Borisovna Zhdanova, Pavel D. Biziaev, Elena B. Dunaeva, Olga V. Chasovskikh
The effect of dynamized forms of Melatonin 6 cH and Lissotriton 6 cH were studied in comparison. Melatonin and Lissotriton are universal stimulantors of regeneration. In animals, melatonin is a hormone regulating circadian rhythms, seasonal reproduction, and many other physiological functions. Lissotriton is the recrystallized and dinamized form of tissue of Lissotriton vulgares. Materials and methods. White laboratory one years old mice of the vivarium of KSMY received a dynamizing form of Melatonin 6 cH and Lissotriton 6 cH at a dose of 5 drops per 20 ml of water for 14 days. The 3-d group was a control. Results. The study showed the best structure of wool, hair and activity of rodents who took Melatonin 6 cH and Lissotriton 6 cH. The coat of the animal becomes bright, healthy and thick, many follicles are visible on histological slides of epidermis and derma (x80). The microscopic examination showed perfect adhering of the cuticle to the cortical layer. Also the forced swimming method confirmed that the dynamic form of Melatonin and Lissotriton increased the adaptability of the animals. Swimming time was 2.5 times longer (Melatonin) and 4 times longer (Lissotriton) compared to control groups.
{"title":"Comparative study of the action of dynamized forms of melatonin and lissotriton","authors":"Olga Borisovna Zhdanova, Pavel D. Biziaev, Elena B. Dunaeva, Olga V. Chasovskikh","doi":"10.51910/ijhdr.v22i2.1361","DOIUrl":"https://doi.org/10.51910/ijhdr.v22i2.1361","url":null,"abstract":"The effect of dynamized forms of Melatonin 6 cH and Lissotriton 6 cH were studied in comparison. Melatonin and Lissotriton are universal stimulantors of regeneration. In animals, melatonin is a hormone regulating circadian rhythms, seasonal reproduction, and many other physiological functions. Lissotriton is the recrystallized and dinamized form of tissue of Lissotriton vulgares. Materials and methods. White laboratory one years old mice of the vivarium of KSMY received a dynamizing form of Melatonin 6 cH and Lissotriton 6 cH at a dose of 5 drops per 20 ml of water for 14 days. The 3-d group was a control. Results. The study showed the best structure of wool, hair and activity of rodents who took Melatonin 6 cH and Lissotriton 6 cH. The coat of the animal becomes bright, healthy and thick, many follicles are visible on histological slides of epidermis and derma (x80). The microscopic examination showed perfect adhering of the cuticle to the cortical layer. Also the forced swimming method confirmed that the dynamic form of Melatonin and Lissotriton increased the adaptability of the animals. Swimming time was 2.5 times longer (Melatonin) and 4 times longer (Lissotriton) compared to control groups.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"223 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139169784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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