Pub Date : 2022-09-27DOI: 10.51910/ijhdr.v21i2.1216
B. Galeazzi, A. Manzalini, S. Cartwright, L. Bonamin, Nss Medeiros, I. Suffredini
Abstract Spectroscopy has been shown to be a useful method to study the physicochemical properties of homeopathic preparations. In this pilot study, the aim was to compare two methods (photon scattering and visible-light spectroscopy) in the physical evaluation of Silicea terra 200cH. Two samples have been examined and compared: Silicea terra 200cH and Sac lac 200cH, both prepared in aqueous solution (Cemon Lab, Italy). Lactose was included because the first 3 potencies of Silicea terra are made by trituration in lactose. In the first test, performed in Italy, slight variations in chrominance and luminance due to micro-vibrational 3D phenomena were analyzed. The principle of the experimental procedure is to modify and analyse the incidence and refraction angles of the light hitting the bottles of liquid under examination. Measurements were made using an innovative camera device developed by Daniele Gullà, called MIRA/CORA (proprietary name). The image sensor is a Charge-Coupled Device (CCD)/ Complementary Metal Oxide Semiconductor (CMOS) with interferential matrix filter. A red laser beam, at wavelength 652 nm, hits the bottle and the variations of scattered light are recorded and measured by the device. All measurements have been performed in a dark room at a constant temperature of 22°C +/- 0,2°C using a filter with very narrow spectral bands (10 nm). Proprietary software analyses the incoming frames showing the spectral variations in amplitude and frequency and then interpolates variation in the measured data within a vibrational range between 0.01 Hz and 10 Hz. The measurements have been repeated three times on both Silicea terra 200cH and Sac lac 200cH within a few minutes of each other. Measurements of the mean entropy of the signals, statistically elaborated with T Student test, yielded a two tailed p value < 0.05, where the entropy of the signal recorded from the Silicea terra 200cH sample was statistically lower than the 200cH Sac lac sample. In the second test, performed in Brazil, variations in absorbance were used to identify Silicea terra 200cH compared with Sac lac 200cH and a control solution of non-succussed 30% alcohol, using six solvatochromic dyes, following the method developed by Cartwright [1,2]. Both homeopathic samples were imported from Italy, diluted 1:100 in 30% hydro-alcoholic solution, and submitted to 100 succussions using an automatic mechanical arm (Denise, AUTIC, Brazil) prior to being tested. Samples were inserted into dyes solutions in a 1:60 ratio, and evaluated by visible spectroscopy (FEMTO Spectrophotometer, Brazil). Dyes were prepared in ethanol P.A., according to previous established methods [3]. Samples and dyes were protected from light during the manipulation and environmental conditions of the laboratory (temperature, humidity, and magnetic flux) were monitored during the tests. Three series in triplicate were performed and the results were analyzed by ANOVA / Tukey, comparing both samples and the uns
{"title":"Silicea terra 200cH evaluated by two different spectroscopy methods: a pilot study","authors":"B. Galeazzi, A. Manzalini, S. Cartwright, L. Bonamin, Nss Medeiros, I. Suffredini","doi":"10.51910/ijhdr.v21i2.1216","DOIUrl":"https://doi.org/10.51910/ijhdr.v21i2.1216","url":null,"abstract":"Abstract \u0000Spectroscopy has been shown to be a useful method to study the physicochemical properties of homeopathic preparations. In this pilot study, the aim was to compare two methods (photon scattering and visible-light spectroscopy) in the physical evaluation of Silicea terra 200cH. Two samples have been examined and compared: Silicea terra 200cH and Sac lac 200cH, both prepared in aqueous solution (Cemon Lab, Italy). Lactose was included because the first 3 potencies of Silicea terra are made by trituration in lactose. In the first test, performed in Italy, slight variations in chrominance and luminance due to micro-vibrational 3D phenomena were analyzed. The principle of the experimental procedure is to modify and analyse the incidence and refraction angles of the light hitting the bottles of liquid under examination. Measurements were made using an innovative camera device developed by Daniele Gullà, called MIRA/CORA (proprietary name). The image sensor is a Charge-Coupled Device (CCD)/ Complementary Metal Oxide Semiconductor (CMOS) with interferential matrix filter. A red laser beam, at wavelength 652 nm, hits the bottle and the variations of scattered light are recorded and measured by the device. All measurements have been performed in a dark room at a constant temperature of 22°C +/- 0,2°C using a filter with very narrow spectral bands (10 nm). Proprietary software analyses the incoming frames showing the spectral variations in amplitude and frequency and then interpolates variation in the measured data within a vibrational range between 0.01 Hz and 10 Hz. The measurements have been repeated three times on both Silicea terra 200cH and Sac lac 200cH within a few minutes of each other. Measurements of the mean entropy of the signals, statistically elaborated with T Student test, yielded a two tailed p value < 0.05, where the entropy of the signal recorded from the Silicea terra 200cH sample was statistically lower than the 200cH Sac lac sample. In the second test, performed in Brazil, variations in absorbance were used to identify Silicea terra 200cH compared with Sac lac 200cH and a control solution of non-succussed 30% alcohol, using six solvatochromic dyes, following the method developed by Cartwright [1,2]. Both homeopathic samples were imported from Italy, diluted 1:100 in 30% hydro-alcoholic solution, and submitted to 100 succussions using an automatic mechanical arm (Denise, AUTIC, Brazil) prior to being tested. Samples were inserted into dyes solutions in a 1:60 ratio, and evaluated by visible spectroscopy (FEMTO Spectrophotometer, Brazil). Dyes were prepared in ethanol P.A., according to previous established methods [3]. Samples and dyes were protected from light during the manipulation and environmental conditions of the laboratory (temperature, humidity, and magnetic flux) were monitored during the tests. Three series in triplicate were performed and the results were analyzed by ANOVA / Tukey, comparing both samples and the uns","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129430961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-27DOI: 10.51910/ijhdr.v21i2.1230
Maria Luiza de Sousa Barbosa, C. de Paula Coelho, Adalberto von Ancken
The present study to report the dissolution of calculus in the ureter in a kitten.
本研究报告了结石在小猫输尿管的溶解。
{"title":"Cantharis dissolves calculus in the ureter of a kitten – Case report","authors":"Maria Luiza de Sousa Barbosa, C. de Paula Coelho, Adalberto von Ancken","doi":"10.51910/ijhdr.v21i2.1230","DOIUrl":"https://doi.org/10.51910/ijhdr.v21i2.1230","url":null,"abstract":"The present study to report the dissolution of calculus in the ureter in a kitten.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"187 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114960815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-27DOI: 10.51910/ijhdr.v21i2.1225
N. Sukul, Sumit Ghosh, R. Singh, N. Pande, A. Sukul
Drugs at high dilution (HD) produce therapeutic effect on man, animals and plants. Experimental evidence shows that free water molecules and hydrogen bond strength of OH groups constitute the physical basis of HDs which are otherwise devoid of original drugs molecules. HDs are produced in aqueous EtOH by serial dilution of a substance with mechanical agitation or succussion in each step, and are called potencies. Three potencies 6 cH, 12 cH and 30 cH of two drugs Anacardium orientale and Natrum muriaticum (NaCl) and their mother tincture (MT) are used in this study. Electronic spectra of these MTs and potencies, all in 90% EtOH, were taken in the wavelength region of 190 nm – 350 nm. The objective is to find out any additional physico-chemical entities in potencies besides the aforesaid two factors. It was reported earlier that charge transfer (CT) interaction accompanies potentization of drugs. This study focused on the CT interaction. The results indicate that spectral pattern and absorbance intensities of the test samples vary from each other. Potentization involves CT interaction in consecutive potencies. Water and EtOH do not form a homogeneous mixture and have aggregates of EtOH and water molecules. CT interactions occur in these individual aggregates and are mostly inter molecular within EtOH or water. These aggregates vary from each other in the test samples. It is concluded that water and EtOH aggregates and their relative distribution constitute additional phyco-chemical basis of potencies.
{"title":"High Dilutions of Drugs show Distinct Variation from each other in their Electronic Spectra","authors":"N. Sukul, Sumit Ghosh, R. Singh, N. Pande, A. Sukul","doi":"10.51910/ijhdr.v21i2.1225","DOIUrl":"https://doi.org/10.51910/ijhdr.v21i2.1225","url":null,"abstract":"Drugs at high dilution (HD) produce therapeutic effect on man, animals and plants. Experimental evidence shows that free water molecules and hydrogen bond strength of OH groups constitute the physical basis of HDs which are otherwise devoid of original drugs molecules. HDs are produced in aqueous EtOH by serial dilution of a substance with mechanical agitation or succussion in each step, and are called potencies. Three potencies 6 cH, 12 cH and 30 cH of two drugs Anacardium orientale and Natrum muriaticum (NaCl) and their mother tincture (MT) are used in this study. Electronic spectra of these MTs and potencies, all in 90% EtOH, were taken in the wavelength region of 190 nm – 350 nm. The objective is to find out any additional physico-chemical entities in potencies besides the aforesaid two factors. It was reported earlier that charge transfer (CT) interaction accompanies potentization of drugs. This study focused on the CT interaction. The results indicate that spectral pattern and absorbance intensities of the test samples vary from each other. Potentization involves CT interaction in consecutive potencies. Water and EtOH do not form a homogeneous mixture and have aggregates of EtOH and water molecules. CT interactions occur in these individual aggregates and are mostly inter molecular within EtOH or water. These aggregates vary from each other in the test samples. It is concluded that water and EtOH aggregates and their relative distribution constitute additional phyco-chemical basis of potencies.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134389477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-27DOI: 10.51910/ijhdr.v21i2.1219
J. Zanco
The reaction of plants to ultra-high dilute substances (UHD) is well known, however, the signaling of the immediate effect still doesn't have a widely accepted methodology. The objective of this experiment was to use non-destructive sampling to find signs of UHD soon after application to plants. The control consisted of untreated purslane [Pilea microphylla (L.) Liebm] plants and imaged with a digital camera Mobius (CMOS 1270x720 pixels) directed at a laser beam (±680 nm) emitted over the plant canopy for 220 seconds, with 6-second intervals. Then, the same plants were treated with Fluoricum acidum 30CH (Fl. ac. 30), and ten minutes later, new images of the leaves were taken to verify the possible existence of reaction patterns of the plants generated by Biospeckle Laser (1,2). Several types of imaging were performed to choose the image pattern, and the NIR type was chosen, generated by the Mobius camera connected directly to a laptop. The images were treated using the THSP algorithm, which generated data to compare the variation of pixel intensity with and without the presence of UHD. Research has shown that "Fl. ac. 30" is identified in purslane plants soon after application and this sign persists for at least 180 minutes after application, with a significant difference from the control at the 1% probability level. Keywords: computational vision; homeopathy signal; dynamic laser speckle
{"title":"use of speckle laser to identify canopy variations in plants subjected to ultra-high diluted substances","authors":"J. Zanco","doi":"10.51910/ijhdr.v21i2.1219","DOIUrl":"https://doi.org/10.51910/ijhdr.v21i2.1219","url":null,"abstract":"The reaction of plants to ultra-high dilute substances (UHD) is well known, however, the signaling of the immediate effect still doesn't have a widely accepted methodology. The objective of this experiment was to use non-destructive sampling to find signs of UHD soon after application to plants. The control consisted of untreated purslane [Pilea microphylla (L.) Liebm] plants and imaged with a digital camera Mobius (CMOS 1270x720 pixels) directed at a laser beam (±680 nm) emitted over the plant canopy for 220 seconds, with 6-second intervals. Then, the same plants were treated with Fluoricum acidum 30CH (Fl. ac. 30), and ten minutes later, new images of the leaves were taken to verify the possible existence of reaction patterns of the plants generated by Biospeckle Laser (1,2). Several types of imaging were performed to choose the image pattern, and the NIR type was chosen, generated by the Mobius camera connected directly to a laptop. The images were treated using the THSP algorithm, which generated data to compare the variation of pixel intensity with and without the presence of UHD. Research has shown that \"Fl. ac. 30\" is identified in purslane plants soon after application and this sign persists for at least 180 minutes after application, with a significant difference from the control at the 1% probability level. \u0000Keywords: computational vision; homeopathy signal; dynamic laser speckle","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127137663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-26DOI: 10.51910/ijhdr.v21i2.1207
L. Faedo, Rovier Verdi, A. Kretzschmar, Julia E. Wright, F. Rayns, P. Boff
The Strawberry ( Fragaria × ananassa Duch .) is the world’s most important berry. Around 9.2 million tonnes of strawberries were produced worldwide in 2021 over approximately 395,844 hectares distributed across almost all continents. However, industrial farming approaches, which include the application of high volumes of pesticides, have placed the fruit on the list of foods most contaminated by pesticide residues. Such management negatively affects food security and environmental sustainability. Agroecology is proposed as a holistic alternative to solve this problem, and within this, some practices associated with homeopathy and biodynamic farming involve the application of high-dynamized dilutions as alternatives to chemical pesticides. Research indicates that the use of high-dynamized dilutions holds the potential to promote crop vitality through building natural equilibrium and resilience of agricultural systems. The objective of this research was to explore the extent to which high-dynamized dilutions can increase the sustainability of commercial strawberry production as well as understand the challenges and benefits of using high-dynamized dilutions in agriculture. To do this, natural and social science methods are combined in a multidisciplinary approach that was developed simultaneously in Brazil and the UK. Results of controlled trials demonstrated that the use of high-dynamized dilutions of Phosphorus 12CH, Sulphur 12 CH, and Kali Carbonicum 12CH positively influenced crop production, pest disease levels, and plant vigor in strawberry plants. In addition, data collected from a web survey and interviews with farmers, researchers, and advisors who work with homeopathy, evidenced the role of homeopathy and biodynamic farming as transformative tools regarding ecological awareness and ecological education, helping to advance the concept of the agriculture organism and subtle aspects of life into agricultural research and society.
草莓(Fragaria × ananassa Duch .)是世界上最重要的浆果。2021年，全球草莓产量约为920万吨，种植面积约为395,844公顷，分布在几乎所有大洲。然而，工业化耕作方法，包括使用大量农药，使这种水果被列入农药残留污染最严重的食品名单。这种管理对粮食安全和环境可持续性产生负面影响。农业生态学被提议作为解决这一问题的整体替代方案，其中，一些与顺势疗法和生物动力农业相关的实践涉及使用高动力稀释剂作为化学农药的替代品。研究表明，通过建立农业系统的自然平衡和恢复力，使用高动态稀释具有促进作物活力的潜力。本研究的目的是探索高活性稀释剂在多大程度上可以增加商业草莓生产的可持续性，以及了解在农业中使用高活性稀释剂的挑战和好处。为此，巴西和英国同时开发了一种多学科方法，将自然科学和社会科学方法结合起来。对照试验结果表明，高浓度稀释磷12CH、硫12CH和炭碱12CH对草莓植株的产量、病虫害水平和植株活力有积极影响。此外，从网络调查和对从事顺势疗法工作的农民、研究人员和顾问的访谈中收集的数据，证明了顺势疗法和生物动力农业作为生态意识和生态教育的变革工具的作用，有助于将农业有机体和生命微妙方面的概念推进到农业研究和社会中。
{"title":"Ecological Strawberry Production: Promoting Crop Vitality with High-Dynamized Dilutions","authors":"L. Faedo, Rovier Verdi, A. Kretzschmar, Julia E. Wright, F. Rayns, P. Boff","doi":"10.51910/ijhdr.v21i2.1207","DOIUrl":"https://doi.org/10.51910/ijhdr.v21i2.1207","url":null,"abstract":"The Strawberry ( Fragaria × ananassa Duch .) is the world’s most important berry. Around 9.2 million tonnes of strawberries were produced worldwide in 2021 over approximately 395,844 hectares distributed across almost all continents. However, industrial farming approaches, which include the application of high volumes of pesticides, have placed the fruit on the list of foods most contaminated by pesticide residues. Such management negatively affects food security and environmental sustainability. Agroecology is proposed as a holistic alternative to solve this problem, and within this, some practices associated with homeopathy and biodynamic farming involve the application of high-dynamized dilutions as alternatives to chemical pesticides. Research indicates that the use of high-dynamized dilutions holds the potential to promote crop vitality through building natural equilibrium and resilience of agricultural systems. The objective of this research was to explore the extent to which high-dynamized dilutions can increase the sustainability of commercial strawberry production as well as understand the challenges and benefits of using high-dynamized dilutions in agriculture. To do this, natural and social science methods are combined in a multidisciplinary approach that was developed simultaneously in Brazil and the UK. Results of controlled trials demonstrated that the use of high-dynamized dilutions of Phosphorus 12CH, Sulphur 12 CH, and Kali Carbonicum 12CH positively influenced crop production, pest disease levels, and plant vigor in strawberry plants. In addition, data collected from a web survey and interviews with farmers, researchers, and advisors who work with homeopathy, evidenced the role of homeopathy and biodynamic farming as transformative tools regarding ecological awareness and ecological education, helping to advance the concept of the agriculture organism and subtle aspects of life into agricultural research and society.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128327426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-26DOI: 10.51910/ijhdr.v21i2.1205
Suhan Nowrooz Mohammad, Leoni Villano Bonamin, João Sarkis Yunes
Cyanobacteria are microorganisms found in different parts of the world. Some genera are cyanotoxins producers a sodium channel blocking neurotoxin (saxitoxins). Some homeopathic preparations have been identified as a remedial action on toxicity models in Artemia salina. This step of the study aimed to observe whether homeopathic products influence the toxicity of Raphidiopsis raciborskii on A. salina. Thus, toxicity tests were carried out on cysts in 96-well plates, using different concentrations of the extract obtained from regular cultivation of R. raciborskii in HCl 0.05M. Then, a pilot study with 22 homeopathic preparations was tested blind in two experimental series against 3 controls check for possible attenuation of the toxicity on Artemia salina cysts hatching rate. The most significant results indicative of bioresilience improvement were seen after the treatment with Nitric acidum 6 cH, Plumbum metallicum 6 cH, isotherapic 200 cH, and Hydrochloric acid 1 cH, being the last one used as a vehicle of the extracts. Thus, these preparations were chosen to be used in the main toxicity experiment, performed blind, in sextuplicate, in two experimental series. All experiments were performed during the first quarter moon. Statistical analysis was performed by two-way ANOVA followed by Tukey, with α=0.05. Nitric acidum 6cH induced a significant reduction of hatching rate (p=0.03), and isotherapic 200cH caused a cyst behavior similar to the unchallenged group, being considered the maximum expression of bioresilience face to the exposition. Epigenetics tests are being carried out to reveal the specific mechanisms involved in these effects.
{"title":"Effects of Homeopathic Preparations on Raphidiopsis raciborskii (Cyanobacteria) Toxicity in Artemia salina Model","authors":"Suhan Nowrooz Mohammad, Leoni Villano Bonamin, João Sarkis Yunes","doi":"10.51910/ijhdr.v21i2.1205","DOIUrl":"https://doi.org/10.51910/ijhdr.v21i2.1205","url":null,"abstract":"Cyanobacteria are microorganisms found in different parts of the world. Some genera are cyanotoxins producers a sodium channel blocking neurotoxin (saxitoxins). Some homeopathic preparations have been identified as a remedial action on toxicity models in Artemia salina. This step of the study aimed to observe whether homeopathic products influence the toxicity of Raphidiopsis raciborskii on A. salina. Thus, toxicity tests were carried out on cysts in 96-well plates, using different concentrations of the extract obtained from regular cultivation of R. raciborskii in HCl 0.05M. Then, a pilot study with 22 homeopathic preparations was tested blind in two experimental series against 3 controls check for possible attenuation of the toxicity on Artemia salina cysts hatching rate. The most significant results indicative of bioresilience improvement were seen after the treatment with Nitric acidum 6 cH, Plumbum metallicum 6 cH, isotherapic 200 cH, and Hydrochloric acid 1 cH, being the last one used as a vehicle of the extracts. Thus, these preparations were chosen to be used in the main toxicity experiment, performed blind, in sextuplicate, in two experimental series. All experiments were performed during the first quarter moon. Statistical analysis was performed by two-way ANOVA followed by Tukey, with α=0.05. Nitric acidum 6cH induced a significant reduction of hatching rate (p=0.03), and isotherapic 200cH caused a cyst behavior similar to the unchallenged group, being considered the maximum expression of bioresilience face to the exposition. Epigenetics tests are being carried out to reveal the specific mechanisms involved in these effects.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116152460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-26DOI: 10.51910/ijhdr.v21i2.1164
M. Wassenhoven, P. Dorfman
Background: Homeopathy is controversial because using highly dilute medicines (high homeopathic potencies, HHP) beyond the Avogadro/Loschmidt limit. Previous publications [1,2] using NMR relaxation revealed the involvement of nanobubbles and/or nanoparticles and/or nanometric superstructures in high potentizations. NTA demonstrated the presence of particles in HHPs [3,4]. With SEM-EDX [5] we observed an ionic diversity common to all preparations including HHPs and significant differences in the relative quantity of each ion between different homeopathic manufacturing lines and controls. FTIR spectroscopy [6] shows that the molecular composition is that of carbonates, primarily sodium bicarbonate. Methods: To observe the materiality of homeopathic medicines a multidisciplinary approach is necessary. In collaboration with several universities we are able to observe these medications with NMR, NTA, SEM-EDX, FTIR, pH and EPA. Results: The essential component of all already studied homeopathic medicines is sodium hydrogen carbonate modulated by some other elements in specific quantity, size and shape. The probability that the observed results could have occurred just by random chance can be rejected (especially above Avogadro limit) p < 0,001. Conclusions: The homeopathic medicines do contain material with a specific ionic composition even in HHPs diluted beyond the Avogadro/Loschmidt limit. This specificity can be attributed to the manufacturing process. These results demonstrate that the step-by-step process (dynamized or not) does not match the theoretical expectations in a dilution process. The starting material and dilution/dynamization method influences the nature of these NPs. The role of carbonates and sodium bicarbonate must be carefully studied in the future. Its aqueous solution is alkaline in nature but it is an amphoteric compound, which means that the compound has both acidic as well as alkaline character. The reaction with acids results in sodium salts and carbonic acid and reaction with basic solution produce carbonates and water. Specific electric fields are indeed detectable.
{"title":"Materiality of Homeopathic Medicines. DynHom Research Program.","authors":"M. Wassenhoven, P. Dorfman","doi":"10.51910/ijhdr.v21i2.1164","DOIUrl":"https://doi.org/10.51910/ijhdr.v21i2.1164","url":null,"abstract":"Background: Homeopathy is controversial because using highly dilute medicines (high homeopathic potencies, HHP) beyond the Avogadro/Loschmidt limit. Previous publications [1,2] using NMR relaxation revealed the involvement of nanobubbles and/or nanoparticles and/or nanometric superstructures in high potentizations. NTA demonstrated the presence of particles in HHPs [3,4]. With SEM-EDX [5] we observed an ionic diversity common to all preparations including HHPs and significant differences in the relative quantity of each ion between different homeopathic manufacturing lines and controls. FTIR spectroscopy [6] shows that the molecular composition is that of carbonates, primarily sodium bicarbonate. \u0000Methods: To observe the materiality of homeopathic medicines a multidisciplinary approach is necessary. In collaboration with several universities we are able to observe these medications with NMR, NTA, SEM-EDX, FTIR, pH and EPA. \u0000Results: The essential component of all already studied homeopathic medicines is sodium hydrogen carbonate modulated by some other elements in specific quantity, size and shape. The probability that the observed results could have occurred just by random chance can be rejected (especially above Avogadro limit) p < 0,001. \u0000Conclusions: The homeopathic medicines do contain material with a specific ionic composition even in HHPs diluted beyond the Avogadro/Loschmidt limit. This specificity can be attributed to the manufacturing process. These results demonstrate that the step-by-step process (dynamized or not) does not match the theoretical expectations in a dilution process. The starting material and dilution/dynamization method influences the nature of these NPs. The role of carbonates and sodium bicarbonate must be carefully studied in the future. Its aqueous solution is alkaline in nature but it is an amphoteric compound, which means that the compound has both acidic as well as alkaline character. The reaction with acids results in sodium salts and carbonic acid and reaction with basic solution produce carbonates and water. Specific electric fields are indeed detectable.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124931507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-26DOI: 10.51910/ijhdr.v21i2.1204
L. Bonamin, Sergio Augusto Ribeiro
Water plays a vital role in adapting natural and human systems in a climate change scenario. Understanding how this fundamental element of life is organized and functioning is essential to gather, disseminate, and advance knowledge about water at the micro and nanostructure level. With developments in the different research areas, the International Panel on Water Structure – IPWS was created during the 8th World Water Forum (WWF) of Brasília in 2018. Just as the Toronto Conference in 1986 was a milestone for the climate agenda to spark a process of the organization by the scientific community of what became the Intergovernmental Panel on Climate Change - IPCC, the 8th World Water Forum held in Brasilia in 2018 became a milestone in the agenda of the micro and nanostructure of water. The IPWS connects leading researchers who develop research on water structure and related fields of knowledge and their most diverse applications from an interdisciplinary perspective. Since 2018, CIRAT – International Center on Water and Transdisciplinarity has been responsible for the executive secretary of the IPWS. In 2020 a partnership between CIRAT and WATER – a Multidisciplinary Research Journal has begun, intending to organize a special edition on Water and Transdisciplinarity to be launched during the 9th WWF, in Dakar, on March 24th, 2022. The whole project was organized by Prof. Leoni Bonamin, from Universidade Paulista, with the support of the Editor-in-Chief of this journal, Prof. Gerald Pollack, from Washington University at Seattle. This special edition aimed to disclose advanced knowledge about water at different structural levels, leading to a new understanding of water in response to the challenges of our century. The focus was on the cross-over of information with technical quality and bold thinking, as shown in Figure 1 below. Homeopathy was included among the themes. It was a multi-step process aiming to offer readers a sample of how frontier science can signal a very different and much more exciting future to the following generations than we usually expect. The objective was to gather scientific quality and allow the authors to propose and discuss hypotheses based on the literature. For this, the manuscripts were initially received, after personal invitations sent to more than 200 researchers in the field, whose contributions were evaluated in a pre-selection based on the scope of WATER. They then went through a thorough two-step peer review process. In the first stage, ad-hoc reviewers were invited to give their opinions. In the second stage, members of the Editorial Board carried out a new detailed analysis of the content to ensure maximum scientific understanding, allowing the authors to be bold in their projects while careful with the methodology. From the Board's organization to the design of the editorial flow and peer review, the entire process was carried out voluntarily by all the actors involved. Thus, the whole editorial process was p
{"title":"Homeopathy and high dilutions in the context of water structure research: the experience in the 9th World Water Forum - 2022","authors":"L. Bonamin, Sergio Augusto Ribeiro","doi":"10.51910/ijhdr.v21i2.1204","DOIUrl":"https://doi.org/10.51910/ijhdr.v21i2.1204","url":null,"abstract":"Water plays a vital role in adapting natural and human systems in a climate change scenario. Understanding how this fundamental element of life is organized and functioning is essential to gather, disseminate, and advance knowledge about water at the micro and nanostructure level. With developments in the different research areas, the International Panel on Water Structure – IPWS was created during the 8th World Water Forum (WWF) of Brasília in 2018. Just as the Toronto Conference in 1986 was a milestone for the climate agenda to spark a process of the organization by the scientific community of what became the Intergovernmental Panel on Climate Change - IPCC, the 8th World Water Forum held in Brasilia in 2018 became a milestone in the agenda of the micro and nanostructure of water. The IPWS connects leading researchers who develop research on water structure and related fields of knowledge and their most diverse applications from an interdisciplinary perspective. Since 2018, CIRAT – International Center on Water and Transdisciplinarity has been responsible for the executive secretary of the IPWS. In 2020 a partnership between CIRAT and WATER – a Multidisciplinary Research Journal has begun, intending to organize a special edition on Water and Transdisciplinarity to be launched during the 9th WWF, in Dakar, on March 24th, 2022. The whole project was organized by Prof. Leoni Bonamin, from Universidade Paulista, with the support of the Editor-in-Chief of this journal, Prof. Gerald Pollack, from Washington University at Seattle. This special edition aimed to disclose advanced knowledge about water at different structural levels, leading to a new understanding of water in response to the challenges of our century. The focus was on the cross-over of information with technical quality and bold thinking, as shown in Figure 1 below. Homeopathy was included among the themes. It was a multi-step process aiming to offer readers a sample of how frontier science can signal a very different and much more exciting future to the following generations than we usually expect. The objective was to gather scientific quality and allow the authors to propose and discuss hypotheses based on the literature. For this, the manuscripts were initially received, after personal invitations sent to more than 200 researchers in the field, whose contributions were evaluated in a pre-selection based on the scope of WATER. They then went through a thorough two-step peer review process. In the first stage, ad-hoc reviewers were invited to give their opinions. In the second stage, members of the Editorial Board carried out a new detailed analysis of the content to ensure maximum scientific understanding, allowing the authors to be bold in their projects while careful with the methodology. From the Board's organization to the design of the editorial flow and peer review, the entire process was carried out voluntarily by all the actors involved. Thus, the whole editorial process was p","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132470422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-26DOI: 10.51910/ijhdr.v21i2.1197
O. Zhdanova
The purpose of the research is studying the efficacy of the phytotherapeutic , and homeopathic drug. Phytotherapeutic drugs have been widely used in parasitology for many years. Also, homeopathic drugs such as Cina have anti-helmintic properties. The possibility of using phytotherapeutic and high dilutions drugs during in the treatment of nematodosis disease has been studied. Two experimental parasitological disease models (aspiculuriosis and trichinelosis) were used. Trichinelosis is a common model of nematodosis of mice [1,2]. Aspiculuris tetraptera a pinworm of mice, is an important parasite in institutions with mice colonies for both research and teaching purposes. The infection is generally asymptomatic. This study aimed at to assess the protective efficiency of homeopathic drug such as Cina C6cH, sphagnum and its complex against experimental trichinosis and aspiculuriosis . An assay was carried out on 80 white outbred mice. These were divided into 6 groups of ten mice each. Group 1 and 4 had sphagnum q.s. per os; group 2 and 5 - desoldering dissolved in water Cina C6cH one time a day per os, the group 3 and 6 received complex sphagnum+ Cina C6cH one time a day per os. The groups 1-3 were inoculated with a dose of 80 ± 5 units of T. spiralis larva per mouse, groups 4-6 had spontaneous aspiculuriosis, group 7 had T. spiralis , group 8 had Aspiculuris tetraptera. After 60 days of trichinellosis incubation, process the mice were euthanized and dissected for evaluation. Maximum protection was obtained in the group of mice 3: T. spiralis detected larvae in animals was 650.5±25.1 larva/animal. Group N2 (Cina C6cH) presented 2840.5±183.3 larva/animal. This was less than control group (4485±430.6 larva/mouse). Also groups 4-6 of mice with aspiculuriosis showed 75%, 80% and 86% efficacy against nematodes.
{"title":"Study of comparative efficacy of the phytotherapeutic complex against nematodes of mice","authors":"O. Zhdanova","doi":"10.51910/ijhdr.v21i2.1197","DOIUrl":"https://doi.org/10.51910/ijhdr.v21i2.1197","url":null,"abstract":"The purpose of the research is studying the efficacy of the phytotherapeutic , and homeopathic drug. Phytotherapeutic drugs have been widely used in parasitology for many years. Also, homeopathic drugs such as Cina have anti-helmintic properties. The possibility of using phytotherapeutic and high dilutions drugs during in the treatment of nematodosis disease has been studied. Two experimental parasitological disease models (aspiculuriosis and trichinelosis) were used. Trichinelosis is a common model of nematodosis of mice [1,2]. Aspiculuris tetraptera a pinworm of mice, is an important parasite in institutions with mice colonies for both research and teaching purposes. The infection is generally asymptomatic. This study aimed at to assess the protective efficiency of homeopathic drug such as Cina C6cH, sphagnum and its complex against experimental trichinosis and aspiculuriosis . \u0000An assay was carried out on 80 white outbred mice. These were divided into 6 groups of ten mice each. Group 1 and 4 had sphagnum q.s. per os; group 2 and 5 - desoldering dissolved in water Cina C6cH one time a day per os, the group 3 and 6 received complex sphagnum+ Cina C6cH one time a day per os. The groups 1-3 were inoculated with a dose of 80 ± 5 units of T. spiralis larva per mouse, groups 4-6 had spontaneous aspiculuriosis, group 7 had T. spiralis , group 8 had Aspiculuris tetraptera. After 60 days of trichinellosis incubation, process the mice were euthanized and dissected for evaluation. Maximum protection was obtained in the group of mice 3: T. spiralis detected larvae in animals was 650.5±25.1 larva/animal. Group N2 (Cina C6cH) presented 2840.5±183.3 larva/animal. This was less than control group (4485±430.6 larva/mouse). Also groups 4-6 of mice with aspiculuriosis showed 75%, 80% and 86% efficacy against nematodes.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131401613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-26DOI: 10.51910/ijhdr.v21i2.1198
Adalberto von Ancken, C. Coelho
Background: The truths surrounding medical practices are seasonally challenged by innovative concepts that can aggregate changing procedures in many degrees. The Galtonian eugenics issues supported the pure-breed idea in dictatorial governments, and introduced mesological studies, turning possible to join genetic concepts to the physiology and psychology of the human organism. Following human medicine, more therapeutic models need to forthcoming in domestic animals. The companionship necessity and the highly responsive behavior have addressed the domestication of dogs and their relationship to owners, to an endpoint that both share the same pathologies. Thus, traditional human concepts of biotypology could be extended to companion animals. Grauvogl (1811-1877) proposed a simple biochemical correlation between physiological states and the miasmas of sick individuals (oxygenoid - syphilis, hydrogenoid - sycosis, carbo-nitrogenoid - psora). Antoine Nebel (1870-1954) correlated biochemical status with the musculoskeletal system and the behavior as well. Leon Vannier (1880-1963) model, whose morphophysiological distortions and behavioral inconsistencies were explained by the carbon element and variations in its bonds with phosphorus or fluor radicals was another attempt to categorize and predefine physiology states. Following the advent of structural and functional identification of thyroid hormone in the 1940s, Henri Bernard described the neuro-morphofunctional plasticity of individuals guided by their predominant embryonic leaflet and consequent hormonal diseases. Methods: This work is a narrative review with the purpose of describing and discussing the legacy from biotypology studies and their applicability in dog therapy, and to propose a new homeopathic approach in veterinary medicine based on the miasmas, also contributing to the scarce available literature. Results: Based on cellular exchanges and consequent metabolic rate, animals can be classified into psoric (no evidence of clinical signs, stable behavior, and adequate exonerative cellular processes); sycotic (cellular dysfunction with alterations in oxidative phosphorylation processes allowing accumulation of cellular toxins such as reactive oxygen and nitrogen species; clinically culminating in chronic inflammations in noble organs, and purulent discharges; unstable and polarized behavior) and syphilitic (whose cellular alterations have reached the molecular level, reducing protein expression and determining cellular toxicity and loss of function; indifferent behavior). Generalities such as temperature influence, weight, thirst and feeding shall also be considered. Discussion and Conclusion: This model could benefit stray animals, newly adopted or even from shelters, whose actual behavior is unknown, and the search for the Simillimum may be impaired.
{"title":"Veterinary Biotypology – a Review and new possibilities","authors":"Adalberto von Ancken, C. Coelho","doi":"10.51910/ijhdr.v21i2.1198","DOIUrl":"https://doi.org/10.51910/ijhdr.v21i2.1198","url":null,"abstract":"Background: The truths surrounding medical practices are seasonally challenged by innovative concepts that can aggregate changing procedures in many degrees. The Galtonian eugenics issues supported the pure-breed idea in dictatorial governments, and introduced mesological studies, turning possible to join genetic concepts to the physiology and psychology of the human organism. Following human medicine, more therapeutic models need to forthcoming in domestic animals. The companionship necessity and the highly responsive behavior have addressed the domestication of dogs and their relationship to owners, to an endpoint that both share the same pathologies. Thus, traditional human concepts of biotypology could be extended to companion animals. Grauvogl (1811-1877) proposed a simple biochemical correlation between physiological states and the miasmas of sick individuals (oxygenoid - syphilis, hydrogenoid - sycosis, carbo-nitrogenoid - psora). Antoine Nebel (1870-1954) correlated biochemical status with the musculoskeletal system and the behavior as well. Leon Vannier (1880-1963) model, whose morphophysiological distortions and behavioral inconsistencies were explained by the carbon element and variations in its bonds with phosphorus or fluor radicals was another attempt to categorize and predefine physiology states. Following the advent of structural and functional identification of thyroid hormone in the 1940s, Henri Bernard described the neuro-morphofunctional plasticity of individuals guided by their predominant embryonic leaflet and consequent hormonal diseases. Methods: This work is a narrative review with the purpose of describing and discussing the legacy from biotypology studies and their applicability in dog therapy, and to propose a new homeopathic approach in veterinary medicine based on the miasmas, also contributing to the scarce available literature. Results: Based on cellular exchanges and consequent metabolic rate, animals can be classified into psoric (no evidence of clinical signs, stable behavior, and adequate exonerative cellular processes); sycotic (cellular dysfunction with alterations in oxidative phosphorylation processes allowing accumulation of cellular toxins such as reactive oxygen and nitrogen species; clinically culminating in chronic inflammations in noble organs, and purulent discharges; unstable and polarized behavior) and syphilitic (whose cellular alterations have reached the molecular level, reducing protein expression and determining cellular toxicity and loss of function; indifferent behavior). Generalities such as temperature influence, weight, thirst and feeding shall also be considered. Discussion and Conclusion: This model could benefit stray animals, newly adopted or even from shelters, whose actual behavior is unknown, and the search for the Simillimum may be impaired.","PeriodicalId":106057,"journal":{"name":"International Journal of High Dilution Research - ISSN 1982-6206","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131945315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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