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Light Polymerization through Glass-ceramics: Influence of Light-polymerizing Unit's Emitted Power and Restoration Parameters (Shade, Translucency, and Thickness) on Transmitted Radiant Power. 通过玻璃陶瓷进行光聚合:光聚合装置的发射功率和修复参数(阴影、半透明度和厚度)对透射辐射功率的影响。
IF 1.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-03-23 DOI: 10.4103/ccd.ccd_124_23
Ra'fat I Farah, Ibrahim A Alblihed, Alhareth A Aljuoie, Bandar Alresheedi

Background: This in vitro study assessed light transmission through ceramic discs varying in shade, translucency, and thickness using light-polymerizing units with different radiant power/flux (RP) outputs.

Methods: Disc-shaped specimens (0.5 mm, 1.0 mm, and 2.0 mm) were made from high and low-translucency glass-ceramic ingots (IPS e.max Press) in shades A1 and A4, totaling 60 discs. Two light-polymerizing units with different power outputs were used, and their emission spectra were verified. The transmitted RP values for each ceramic specimen were measured and irradiance and radiant energy influx were calculated. Differences between the light-polymerizing units and the influence of the three ceramic parameters were evaluated using an independent-samples t-test and three-way analysis of variance (ANOVA) tests (α = 0.05).

Results: A statistically significant difference was observed in the mean transmitted RP values between the two light-polymerizing units. Furthermore, the three-way ANOVA test showed a significant effect of shade, translucency, and thickness, as well as a significant interaction between each pair of variables and all three variables on the transmitted RP (P < 0.05).

Conclusions: Despite the significant attenuation in the transmitted RP, especially in ceramics with higher shade chromaticity and thickness and lower translucency, the calculated minimal irradiance values for both light-polymerizing units (their emitted power ≥ 500 mW) were greater than the minimum recommended irradiance threshold (100 mW/cm2). However, the exposure duration needs to be increased to provide the resin with sufficient radiant exposure for adequate polymerization.

背景:这项体外研究使用具有不同辐射功率/流量(RP)输出的光聚合装置,评估了不同色调、半透明度和厚度的陶瓷圆盘的透光率:圆盘状试样(0.5 毫米、1.0 毫米和 2.0 毫米)由高透光度和低透光度玻璃陶瓷锭(IPS e.max Press)制成,色调为 A1 和 A4,共 60 个圆盘。使用了两种不同功率输出的光聚合装置,并对其发射光谱进行了验证。测量了每个陶瓷试样的透射 RP 值,并计算了辐照度和辐射能流入量。使用独立样本 t 检验和三方方差分析 (ANOVA) 检验(α = 0.05)评估了光聚合装置之间的差异和三个陶瓷参数的影响:结果:两种光聚合装置的平均透射 RP 值在统计学上存在明显差异。此外,三方方差分析测试表明,遮光率、半透明度和厚度对透射 RP 有显著影响,每对变量与所有三个变量之间也有显著的交互作用(P < 0.05):尽管透射 RP 有明显的衰减,特别是在色度和厚度较高、半透明度较低的陶瓷中,但两种光聚合装置计算出的最小辐照度值(其发射功率≥ 500 mW)都大于推荐的最小辐照度阈值(100 mW/cm2)。不过,需要延长照射时间,以便为树脂提供足够的辐射照射,使其充分聚合。
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引用次数: 0
Antibacterial Effects of Silver Diamine Fluoride with and without Potassium Iodide against Streptococcus mutans. 含碘化钾和不含碘化钾的二卤化银对变异链球菌的抗菌作用
IF 1.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-03-23 DOI: 10.4103/ccd.ccd_393_23
Carlos Alonso Alvarez-Marín, Norma Leticia Robles-Bermeo, Wael Hegazy Hassan Moustafa, Carlo Eduardo Medina-Solís

Introduction: Silver diamine fluoride (SDF) is a topical treatment for carious lesions and a primary preventative for newly exposed high-risk surfaces such as fissures and roots in the first molars. Using potassium iodide (KI) after applying SDF has been recommended as a way of reducing the severity of black staining, as well as preserving its antibacterial effect useful in deep caries.

Objective: The objective of this research was to compare the antibacterial effect of SDF, with and without KI, on Streptococcus mutans (S. mutans) and dental biofilm.

Methods: The antibacterial effects of SDF, KI, and the combination of both were measured using three different techniques (inhibition halo, minimum inhibitory effect [MIE], and colony-forming unit [CFU], testing).

Results: The results were then subjected to statistical analysis. Analyzed by means of the Kruskal-Wallis statistical test, the inhibition halos yielded a value of P = 0.3309. Using the MIE test, only the SDF treatment produced an antibacterial effect, at 10%, compared to the KI group, with P = 0.001. Finally, the CFU test revealed a total absence of colonies for all three reagents. All three substances analyzed achieved total inhibition of S. mutans. SDF is effective even in its minimal commercial concentration. Its antibacterial capacity decreases with the addition of KI.

Conclusions: The three substances analyzed at their maximum concentrations exhibited an antibacterial effect against S. mutans, resulting in total inhibition.

简介:二胺氟化银(SDF)是一种局部治疗龋损的药物,也是第一磨牙裂隙和牙根等新暴露的高风险表面的主要预防药物。有人建议在涂抹 SDF 后使用碘化钾(KI),以减轻黑斑的严重程度,并保持其对深龋有用的抗菌效果:本研究的目的是比较含 KI 和不含 KI 的 SDF 对变异链球菌(S. mutans)和牙齿生物膜的抗菌效果:方法:采用三种不同的技术(抑菌晕、最小抑菌作用[MIE]和菌落形成单位[CFU]测试)测量 SDF、KI 以及两者的组合的抗菌效果:然后对结果进行统计分析。通过 Kruskal-Wallis 统计检验进行分析,抑制光环的检验值为 P = 0.3309。通过 MIE 检验,与 KI 组相比,只有 SDF 处理产生了 10%的抗菌效果,P = 0.001。最后,CFU 检验显示,所有三种试剂都不产生菌落。所分析的三种物质都能完全抑制 S. mutans。SDF 即使在最低商业浓度下也有效。结论:结论:所分析的三种物质在其最大浓度下对变异杆菌都有抗菌作用,从而达到完全抑制的效果。
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引用次数: 0
Oral Manifestations of Multiple Endocrine Neoplasia 2B Syndrome: A Rare Case Report. 多发性内分泌肿瘤 2B 综合征的口腔表现:罕见病例报告
IF 1.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-03-23 DOI: 10.4103/ccd.ccd_215_23
Sohini Banerjee, Debkamal Kar

Multiple endocrine neoplasia (MEN) 2B syndrome is a rare autosomal dominant hereditary condition of neuroendocrine origin characterized by pheochromocytoma, marfanoid habitus, and mucocutaneous neuromas. Multiple mucosal neuromas on the tongue, lips, cheeks, and inner eyelids are often appeared as the earliest signs in most of the undiagnosed cases. Early diagnoses, recognition of phenotype, adequate surgery, and appropriate genetic counseling are very much essential as patients often develop medullary thyroid carcinoma (MTC) and pheochromocytoma. This case report would highlight the oral manifestations of MEN 2B in a 22-year-old female patient with multiple mucosal neuromas and a previous history of thyroidectomy due to MTC.

多发性内分泌肿瘤(MEN)2B 综合征是一种罕见的常染色体显性遗传性神经内分泌疾病,以嗜铬细胞瘤、马凡诺型体型和粘膜神经瘤为特征。在大多数未确诊的病例中,舌头、嘴唇、脸颊和眼睑内侧的多发性粘膜神经瘤往往是最早出现的症状。由于患者通常会发展为甲状腺髓样癌和嗜铬细胞瘤,因此早期诊断、识别表型、适当手术和适当的遗传咨询非常重要。本病例报告将重点介绍一名22岁女性患者的MEN 2B口腔表现,该患者患有多发性粘膜神经瘤,既往曾因MTC而进行过甲状腺切除术。
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引用次数: 0
Decipher the Cipher. 破译密码
IF 1.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-03-23 DOI: 10.4103/ccd.ccd_112_24
Girish Malleshappa Sogi
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引用次数: 0
Assessing Conservative Treatment Options for Odontogenic Keratocyst in a 12-Year-Old Patient, with 1-Year Follow-up. 评估一名 12 岁患者牙源性角化囊肿的保守治疗方案,并进行 1 年随访。
IF 1.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-03-23 DOI: 10.4103/ccd.ccd_409_23
Jean N Murry, Anshul Gangwar, Mongshithung N Murry

The odontogenic keratocyst (OKC) is a frequently developing odontogenic cyst that accounts for 10%-14% of all jaw cysts. Due to the high recurrence rate, aggressive therapeutic techniques such as jaw resection and marsupialization are indicated. Following a conservative marsupialization procedure in which Carnoy's solution and an iodoform packing were used, the clinical, radiological, and histological evaluation of OKC in a 12-year-old female patient revealed no evidence of recurrence over the subsequent year of follow-up.

牙源性角化囊肿(OKC)是一种常发的牙源性囊肿,占所有颌骨囊肿的 10%-14%。由于复发率较高,因此需要采用积极的治疗技术,如颌骨切除术和龈上皮化生术。一名 12 岁的女患者在使用卡诺伊溶液和碘仿填料进行保守性龋囊切除术后,对 OKC 进行了临床、放射学和组织学评估,结果显示在随后一年的随访中没有发现复发的迹象。
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引用次数: 0
Ethical Issues in the Planning and the Conduct of Escape Rooms in Medical Education. 在医学教育中规划和开展逃生室的伦理问题。
IF 1.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-03-23 DOI: 10.4103/ccd.ccd_571_23
Saurabh RamBihariLal Shrivastava, Mayur Wanjari

Escape rooms in medical education are relatively a novel approach to facilitate critical thinking and decision-making in simulated realistic clinical scenarios among the medical students. The success of escape rooms in the attainment of specified competencies depends on several factors that must be given due consideration for optimizing the overall outcome. Further, there might be multiple ethical concerns that must be given due attention before, during, and after the conduct of such sessions. There is an immense need to integrate ethical considerations while designing and implementing escape rooms in medical schools, as it will aid in the creation of a respectful and encouraging learning atmosphere for the students. In conclusion, escape rooms provide a great learning opportunity for medical students to critically think, engage in teamwork, and learn the art of adaptation depending on the given clinical scenario. However, the successful conduct of such sessions is determined by a wide range of factors, including ethical considerations, and all of them need to be systematically analyzed and measures should be taken to reduce their impact on students.

医学教育中的逃生室是一种相对新颖的方法,可促进医学生在模拟真实的临床场景中进行批判性思维和决策。逃生室能否成功实现特定的能力取决于几个因素,必须适当考虑这些因素,以优化整体结果。此外,在进行此类课程之前、期间和之后,可能会有多种伦理问题必须给予应有的关注。在医学院校设计和实施密室逃脱课程时,亟需纳入伦理方面的考虑,因为这将有助于为学生营造一种相互尊重、令人鼓舞的学习氛围。总之,密室逃脱为医科学生提供了一个绝佳的学习机会,让他们能够进行批判性思考、参与团队合作并学习根据特定临床场景进行调整的艺术。然而,能否成功开展此类课程取决于多种因素,包括伦理方面的考虑,需要对所有这些因素进行系统分析,并采取措施减少其对学生的影响。
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引用次数: 0
Three-dimensional Assessment of Temporomandibular Joint Volume, and Condylar and Glenoid-fossa Morphology: A Cone-beam Computed Tomography Study. 颞下颌关节体积以及髁状突和盂窝形态的三维评估:锥形束计算机断层扫描研究。
IF 1.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-10-01 Epub Date: 2023-12-19 DOI: 10.4103/ccd.ccd_254_23
Shivam Mehta, Vaibhav Gandhi, Apexa Patel, Po-Jung Chen, Meng-Hsuan Lin, Chia-Ling Kuo, Aditya Tadinada, Sumit Yadav

Background: The condylar and glenoid fossa morphology can alter in patients with temporomandibular disorders (TMD), which can lead to changes in the temporomandibular joint (TMJ) space volume. Volumetric evaluation of TMJ can represent the entire three-dimensional (3D)-joint space between the condyle and glenoid fossa.

Aims: To perform 3D assessment of TMJ volume, condylar, and glenoid-fossa morphology using cone-beam computed tomography and evaluate the correlation between these parameters.

Settings and design: Thirty-four patients (age: 13.50 years) who had no previous history of TMD were included.

Materials and methods: The volume of TMJ space was measured and divided into anterior, posterior, medial, and lateral TMJ volume. The antero-posterior (AP) and medio-lateral (ML) condylar width, AP and ML glenoid-fossa width, and glenoid-fossa depth were evaluated.

Statistical analysis used: Statistical analyses were performed with R software at a 0.05 significance level. Each parameter was compared between the left and right sides using a paired-t test. The correlations between the parameters were obtained by the Pearson correlation coefficient.

Results: There was no significant difference between lateral and medial TMJ volume; however, posterior TMJ volume was significantly greater than anterior TMJ volume. A significant correlation was observed between AP glenoid-fossa width and TMJ volume, glenoid-fossa depth and TMJ volume, AP position of the condyle and anterior TMJ volume, ML position of the condyle and medial TMJ volume, glenoid-fossa width and condyle width in AP and ML dimension, glenoid-fossa depth and AP glenoid-fossa width.

Conclusions: In addition to the evaluation of condylar and glenoid-fossa morphology, assessment of TMJ space volume is important for comprehensive evaluation of the joint.

背景:颞下颌关节紊乱症(TMD)患者的髁状突和盂窝形态会发生改变,从而导致颞下颌关节(TMJ)空间体积发生变化。颞下颌关节的容积评估可以代表髁状突和盂窝之间的整个三维(3D)关节空间。目的:使用锥束计算机断层扫描对颞下颌关节容积、髁状突和盂窝形态进行三维评估,并评估这些参数之间的相关性:34名既往无TMD病史的患者(年龄:13.50岁):测量颞下颌关节间隙的体积,并将其分为颞下颌关节前部、后部、内侧和外侧的体积。评估了髁状突前后(AP)和内外侧(ML)宽度、AP 和 ML盂窝宽度以及盂窝深度:使用 R 软件进行统计分析,显著性水平为 0.05。采用配对 t 检验比较左右两侧的各项参数。参数之间的相关性通过皮尔逊相关系数得出:结果:颞下颌关节外侧和内侧的体积无明显差异;但颞下颌关节后侧的体积明显大于颞下颌关节前侧的体积。AP盂窝宽度与颞下颌关节体积、盂窝深度与颞下颌关节体积、髁状突的AP位置与颞下颌关节前部体积、髁状突的ML位置与颞下颌关节内侧体积、盂窝宽度与髁状突在AP和ML维度上的宽度、盂窝深度与AP盂窝宽度之间存在明显相关性:除了髁状突和盂窝形态的评估外,颞下颌关节间隙容积的评估对于关节的综合评估也很重要。
{"title":"Three-dimensional Assessment of Temporomandibular Joint Volume, and Condylar and Glenoid-fossa Morphology: A Cone-beam Computed Tomography Study.","authors":"Shivam Mehta, Vaibhav Gandhi, Apexa Patel, Po-Jung Chen, Meng-Hsuan Lin, Chia-Ling Kuo, Aditya Tadinada, Sumit Yadav","doi":"10.4103/ccd.ccd_254_23","DOIUrl":"https://doi.org/10.4103/ccd.ccd_254_23","url":null,"abstract":"<p><strong>Background: </strong>The condylar and glenoid fossa morphology can alter in patients with temporomandibular disorders (TMD), which can lead to changes in the temporomandibular joint (TMJ) space volume. Volumetric evaluation of TMJ can represent the entire three-dimensional (3D)-joint space between the condyle and glenoid fossa.</p><p><strong>Aims: </strong>To perform 3D assessment of TMJ volume, condylar, and glenoid-fossa morphology using cone-beam computed tomography and evaluate the correlation between these parameters.</p><p><strong>Settings and design: </strong>Thirty-four patients (age: 13.50 years) who had no previous history of TMD were included.</p><p><strong>Materials and methods: </strong>The volume of TMJ space was measured and divided into anterior, posterior, medial, and lateral TMJ volume. The antero-posterior (AP) and medio-lateral (ML) condylar width, AP and ML glenoid-fossa width, and glenoid-fossa depth were evaluated.</p><p><strong>Statistical analysis used: </strong>Statistical analyses were performed with R software at a 0.05 significance level. Each parameter was compared between the left and right sides using a paired-t test. The correlations between the parameters were obtained by the Pearson correlation coefficient.</p><p><strong>Results: </strong>There was no significant difference between lateral and medial TMJ volume; however, posterior TMJ volume was significantly greater than anterior TMJ volume. A significant correlation was observed between AP glenoid-fossa width and TMJ volume, glenoid-fossa depth and TMJ volume, AP position of the condyle and anterior TMJ volume, ML position of the condyle and medial TMJ volume, glenoid-fossa width and condyle width in AP and ML dimension, glenoid-fossa depth and AP glenoid-fossa width.</p><p><strong>Conclusions: </strong>In addition to the evaluation of condylar and glenoid-fossa morphology, assessment of TMJ space volume is important for comprehensive evaluation of the joint.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"14 4","pages":"256-264"},"PeriodicalIF":1.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10855514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139721924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional Status, Prevalence of Early Childhood Caries, and its Association among Preschool Children in Northeast India. 印度东北部学龄前儿童的营养状况、幼儿龋齿患病率及其关联。
IF 1.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-10-01 Epub Date: 2023-12-19 DOI: 10.4103/ccd.ccd_290_23
Nandita Kshetrimayum, Sibyl Siluvai, Prabhat Kumar Chaudhuri, Talisunup Longkumar, Darshana Bennadi, Victor Rakesh Lazar

Background: Early childhood caries (ECC) is a common public health problem in developing countries. Children with severe decay can also have altered eating habits and preferences. Therefore, ECC can influence nutritional health.

Aim: The aim is to find the prevalence of ECC and nutritional status and to evaluate its association among preschool children in Northeast India.

Study design and data collection methods: This descriptive cross-sectional study was conducted among 384 preschool children aged 2-6 years. The sampling unit comprised the children attending the pediatric dentistry department of one dental college. Information regarding sociodemographic factors, child feeding habits, and child oral hygiene practices was obtained from the parents using a pretested questionnaire. Weight and height were evaluated to assess the nutritional status. The decay, missing, filled teeth index for primary teeth was used to determine the dental caries status.

Results: The mean value of carious teeth for 384 children aged 2-6 years was 5.6 ± 2.43. Most kids who had caries (74.7%) belonged to the moderate category (dmft >7), followed by the low sort, which was 16.7%, and then by those in the higher class (8.6%). The body mass index (BMI) for age revealed that 5.2% were overweight, 15.1% were thin, and 8.3% were obese. Most of those with high caries (i.e., dmft >7) were underweight or in the normal weight category. Pearson correlation showed no significant correlation between ECC with BMI-for-age (r = 0.04, P > 0.05).

Conclusion: The prevalence of dental caries among children below the age of 5 years in Imphal was high. The risk factors for ECC included age, low maternal education, improper feeding, and oral hygiene habits. However, the results revealed no significant relationship between ECC and BMI.

背景:儿童早期龋齿(ECC)是发展中国家常见的公共卫生问题。严重龋齿儿童的饮食习惯和偏好也会发生改变。研究设计和数据收集方法:这项描述性横断面研究的对象是 384 名 2-6 岁的学龄前儿童。抽样单位包括在一所牙科学院儿童牙科系就诊的儿童。研究人员通过事先测试的调查问卷从家长处获得了有关社会人口学因素、儿童喂养习惯和儿童口腔卫生习惯的信息。通过评估体重和身高来评估营养状况。采用乳牙龋齿、缺失、补牙指数来确定龋齿状况:结果:384 名 2-6 岁儿童的龋齿平均值为 5.6 ± 2.43。大多数龋齿儿童(74.7%)属于中度龋齿(dmft>7),其次是低度龋齿(16.7%),然后是高度龋齿(8.6%)。按年龄计算的体重指数(BMI)显示,5.2%的人超重,15.1%的人偏瘦,8.3%的人肥胖。大部分龋坏程度高(即 dmft >7)的人体重不足或属于正常体重。皮尔逊相关性显示,龋齿率与年龄体重指数(BMI)之间无明显相关性(r = 0.04,P > 0.05):结论:英帕尔 5 岁以下儿童的龋齿患病率很高。龋齿的风险因素包括年龄、母亲受教育程度低、喂养不当和口腔卫生习惯。然而,研究结果显示,龋齿与体重指数之间没有明显关系。
{"title":"Nutritional Status, Prevalence of Early Childhood Caries, and its Association among Preschool Children in Northeast India.","authors":"Nandita Kshetrimayum, Sibyl Siluvai, Prabhat Kumar Chaudhuri, Talisunup Longkumar, Darshana Bennadi, Victor Rakesh Lazar","doi":"10.4103/ccd.ccd_290_23","DOIUrl":"https://doi.org/10.4103/ccd.ccd_290_23","url":null,"abstract":"<p><strong>Background: </strong>Early childhood caries (ECC) is a common public health problem in developing countries. Children with severe decay can also have altered eating habits and preferences. Therefore, ECC can influence nutritional health.</p><p><strong>Aim: </strong>The aim is to find the prevalence of ECC and nutritional status and to evaluate its association among preschool children in Northeast India.</p><p><strong>Study design and data collection methods: </strong>This descriptive cross-sectional study was conducted among 384 preschool children aged 2-6 years. The sampling unit comprised the children attending the pediatric dentistry department of one dental college. Information regarding sociodemographic factors, child feeding habits, and child oral hygiene practices was obtained from the parents using a pretested questionnaire. Weight and height were evaluated to assess the nutritional status. The decay, missing, filled teeth index for primary teeth was used to determine the dental caries status.</p><p><strong>Results: </strong>The mean value of carious teeth for 384 children aged 2-6 years was 5.6 ± 2.43. Most kids who had caries (74.7%) belonged to the moderate category (dmft >7), followed by the low sort, which was 16.7%, and then by those in the higher class (8.6%). The body mass index (BMI) for age revealed that 5.2% were overweight, 15.1% were thin, and 8.3% were obese. Most of those with high caries (i.e., dmft >7) were underweight or in the normal weight category. Pearson correlation showed no significant correlation between ECC with BMI-for-age (<i>r</i> = 0.04, <i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>The prevalence of dental caries among children below the age of 5 years in Imphal was high. The risk factors for ECC included age, low maternal education, improper feeding, and oral hygiene habits. However, the results revealed no significant relationship between ECC and BMI.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"14 4","pages":"300-306"},"PeriodicalIF":1.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10855516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139721922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gorlin-Goltz Syndrome: Report of a Rare Case with an Update on the Review of the Literature. 戈林-戈尔茨综合征:罕见病例报告及最新文献综述。
IF 1.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-10-01 Epub Date: 2023-12-19 DOI: 10.4103/ccd.ccd_139_23
Shylaja Attur, Jigar Kumar Patel, Kailash Attur, Sailesh Menat

Keratocyst is a developmental odontogenic cyst arising from remnants/rests of the dental lamina with biologic behavior similar to benign neoplasm. The presence of multiple odontogenic keratocysts is rare and seen in Gorlin-Goltz syndrome (GGS). GGS syndrome presents with multisystem involvement and the classical triad of multiple basocellular epitheliomas, keratocysts in the jaws, and bifid ribs; that characterize the diagnosis of this syndrome. Multiple odontogenic keratocyst are the most consistent features of the syndrome in 65%-100% of affected individuals and are generally diagnosed at a very early age. Early diagnosis and proper counseling of the parent and patient might help to reduce the morbidity, encourage follow-up for timely treatment, and help in avoiding ionizing radiation that would lead to the development of malignancies.

角化囊肿是一种发育性的牙源性囊肿,产生于牙本质的残余部分,其生物学行为类似于良性肿瘤。多发性牙源性角化囊肿很少见,多见于戈林-戈尔茨综合征(GGS)。多发性牙源性角化囊肿综合征表现为多系统受累以及多发性基底细胞上皮瘤、颌骨角化囊肿和双裂肋骨的经典三联征,是该综合征的诊断特征。多发性牙源性角化囊肿是该综合征最一致的特征,在 65%-100% 的患者中都会出现,而且通常在很小的时候就能确诊。及早诊断并为家长和患者提供适当的咨询可能有助于降低发病率,鼓励及时治疗,并有助于避免电离辐射导致恶性肿瘤的发生。
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引用次数: 0
Efficacy of Enamel Matrix Derivative in Periodontal Regeneration Defects: A Systematic Review and Meta-Analysis. 牙釉质基质衍生物对牙周再生缺陷的疗效:系统回顾与元分析》。
IF 1.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-10-01 Epub Date: 2023-12-19 DOI: 10.4103/ccd.ccd_97_23
Frank Mayta-Tovalino, Carlos Diaz-Arocutipa, John Barja-Ore, Adrian V Hernandez

Aim: To evaluate the efficacy of enamel matrix derivative (EMD) on periodontal regeneration defects.

Materials and methods: Four databases were searched until October 2021. Experimental animal studies evaluating the efficacy of EMD were used. The primary outcomes were bone formation (BF) and cementum formation (CF). The secondary outcomes were junctional epithelium (JE), gingival recession (GR), and clinical attachment level (CAL). Measures of effect were mean difference (MD) with 95% confidence intervals (CIs). Random-effects model were used for all meta-analyses. The Systematic Review Centre for Laboratory animal Experimentation tool was used to assess the risk of bias.

Results: Seven experimental animal studies (n = 40) used with a maximum follow-up period of 3 months. Compared to control, EMD did not significantly reduce BF (MD 0.02 mm; 95% CI - 1.91-1.96; I2 = 89%). However, it increased CF (MD 1.38 mm; 95% CI 0.01-2.74; I2 = 55%). For secondary outcomes it was found that compared to control, EMD only significantly reduced JE (MD - 0.54 mm; 95% CI - 1.06 to - 0.02; I2 = 55%). However, the other secondary outcomes were not significant as in the case of GR (MD - 3. 88 mm; 95% CI - 68.29-60.53; I2 = 82%), and in CAL (MD 0.02 mm; 95% CI - 0.29-0.39; I2 = 38%). Finally, according to the risk of bias assessment, all included studies had a high risk of bias.

Conclusion: EMD had no effect on BF values while it did not reduce CF. Otherwise, in the secondary outcomes, EMD only significantly reduced JE values and had no effect on GR and CAL.

目的:评估牙釉质基质衍生物(EMD)对牙周再生缺损的疗效:截至 2021 年 10 月,共检索了四个数据库。使用了评估 EMD 疗效的动物实验研究。主要结果是骨形成(BF)和骨水泥形成(CF)。次要结果为交界上皮(JE)、牙龈退缩(GR)和临床附着水平(CAL)。疗效的衡量标准为平均差 (MD) 和 95% 置信区间 (CI)。所有荟萃分析均采用随机效应模型。实验动物实验系统综述中心工具用于评估偏倚风险:七项实验动物研究(n = 40)的随访期最长为 3 个月。与对照组相比,EMD并未显著降低BF(MD 0.02 mm; 95% CI - 1.91-1.96; I2 = 89%)。然而,它却增加了CF(MD 1.38 mm; 95% CI 0.01-2.74; I2 = 55%)。对于次要结果,研究发现,与对照组相比,EMD仅显著降低了JE(MD - 0.54 mm; 95% CI - 1.06 to - 0.02; I2 = 55%)。然而,其他次要结果并不显著,如GR(MD - 3. 88 mm; 95% CI - 68.29-60.53; I2 = 82%)和CAL(MD 0.02 mm; 95% CI - 0.29-0.39; I2 = 38%)。最后,根据偏倚风险评估,所有纳入研究的偏倚风险都很高:结论:EMD对BF值没有影响,同时也没有降低CF值。此外,在次要结果中,EMD 只显著降低了 JE 值,而对 GR 和 CAL 没有影响。
{"title":"Efficacy of Enamel Matrix Derivative in Periodontal Regeneration Defects: A Systematic Review and Meta-Analysis.","authors":"Frank Mayta-Tovalino, Carlos Diaz-Arocutipa, John Barja-Ore, Adrian V Hernandez","doi":"10.4103/ccd.ccd_97_23","DOIUrl":"https://doi.org/10.4103/ccd.ccd_97_23","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the efficacy of enamel matrix derivative (EMD) on periodontal regeneration defects.</p><p><strong>Materials and methods: </strong>Four databases were searched until October 2021. Experimental animal studies evaluating the efficacy of EMD were used. The primary outcomes were bone formation (BF) and cementum formation (CF). The secondary outcomes were junctional epithelium (JE), gingival recession (GR), and clinical attachment level (CAL). Measures of effect were mean difference (MD) with 95% confidence intervals (CIs). Random-effects model were used for all meta-analyses. The Systematic Review Centre for Laboratory animal Experimentation tool was used to assess the risk of bias.</p><p><strong>Results: </strong>Seven experimental animal studies (<i>n</i> = 40) used with a maximum follow-up period of 3 months. Compared to control, EMD did not significantly reduce BF (MD 0.02 mm; 95% CI - 1.91-1.96; <i>I</i><sup>2</sup> = 89%). However, it increased CF (MD 1.38 mm; 95% CI 0.01-2.74; <i>I</i><sup>2</sup> = 55%). For secondary outcomes it was found that compared to control, EMD only significantly reduced JE (MD - 0.54 mm; 95% CI - 1.06 to - 0.02; <i>I</i><sup>2</sup> = 55%). However, the other secondary outcomes were not significant as in the case of GR (MD - 3. 88 mm; 95% CI - 68.29-60.53; <i>I</i><sup>2</sup> = 82%), and in CAL (MD 0.02 mm; 95% CI - 0.29-0.39; <i>I</i><sup>2</sup> = 38%). Finally, according to the risk of bias assessment, all included studies had a high risk of bias.</p><p><strong>Conclusion: </strong>EMD had no effect on BF values while it did not reduce CF. Otherwise, in the secondary outcomes, EMD only significantly reduced JE values and had no effect on GR and CAL.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"14 4","pages":"249-255"},"PeriodicalIF":1.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10855512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139721919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Contemporary Clinical Dentistry
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