The complaints of sore throat and cough are the symptoms that we encounter frequently in our daily routine, and it is important to remember that if not thoroughly examined, different underlying diseases can be revealed. Our case was applied to the family medicine outpatient clinic with complaints of sore throat and cough, and a mass appearance was observed during the chest radiography requested due to abnormal findings from the sounds coming from the patient's lung. Thus, the mass was detected early, and we presented the patient with the diagnosis of Schwannoma, whose mass was removed.
{"title":"Öksürük belirtisi sonrası Schwannoma tanısı konulan bir olgu","authors":"İzzet FİDANCI, Hilal AKSOY, Duygu AYHAN BAŞER","doi":"10.17826/cumj.1311171","DOIUrl":"https://doi.org/10.17826/cumj.1311171","url":null,"abstract":"The complaints of sore throat and cough are the symptoms that we encounter frequently in our daily routine, and it is important to remember that if not thoroughly examined, different underlying diseases can be revealed. Our case was applied to the family medicine outpatient clinic with complaints of sore throat and cough, and a mass appearance was observed during the chest radiography requested due to abnormal findings from the sounds coming from the patient's lung. Thus, the mass was detected early, and we presented the patient with the diagnosis of Schwannoma, whose mass was removed.","PeriodicalId":10748,"journal":{"name":"Cukurova Medical Journal","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136278808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Göktuğ EFGAN, Umut PAYZA, Osman Sezer ÇINAROĞLU, Ecem ERMETE GÜLER, Ahmet KAYALI
Purpose: This study evaluated patients diagnosed with acute pancreatitis in the emergency department by comparing the BUN/Albumin Ratio (BAR) and BISAP scores to indicate disease severity and prognosis.
Materials and Methods: 457 patients diagnosed with acute pancreatitis between 2016 and 2021 were included in this observational study, which was planned retrospectively. The laboratory data of the patients and the calculated BISAP scores were recorded.
Results: Patients were categorized according to the BISAP score; 385 (84.2%) patients were at low risk for acute pancreatitis, while 72 (15.8%) were at high risk. The AUC for BAR values was 0.757 (75.7%), and this was statistically significant for determining cutoff values, with a cutoff value of >4.60 (p
目的:本研究通过比较BUN/Albumin Ratio (BAR)和BISAP评分来评估急诊科诊断为急性胰腺炎的患者的病情严重程度和预后。材料和方法:本观察性研究纳入了2016年至2021年间诊断为急性胰腺炎的457例患者，回顾性计划。记录患者的实验室数据和计算的BISAP评分。& # x0D;结果:根据BISAP评分对患者进行分类;急性胰腺炎低危385例(84.2%)，高危72例(15.8%)。BAR值的AUC为0.757(75.7%)，这对于确定截断值具有统计学意义，截断值为4.60 (p
{"title":"Akut pankreatitte şiddetin öngörülmesinde BUN/albümin oranı ile BISAP skorunun karşılaştırılması","authors":"Mehmet Göktuğ EFGAN, Umut PAYZA, Osman Sezer ÇINAROĞLU, Ecem ERMETE GÜLER, Ahmet KAYALI","doi":"10.17826/cumj.1334913","DOIUrl":"https://doi.org/10.17826/cumj.1334913","url":null,"abstract":"Purpose: This study evaluated patients diagnosed with acute pancreatitis in the emergency department by comparing the BUN/Albumin Ratio (BAR) and BISAP scores to indicate disease severity and prognosis.
 Materials and Methods: 457 patients diagnosed with acute pancreatitis between 2016 and 2021 were included in this observational study, which was planned retrospectively. The laboratory data of the patients and the calculated BISAP scores were recorded. 
 Results: Patients were categorized according to the BISAP score; 385 (84.2%) patients were at low risk for acute pancreatitis, while 72 (15.8%) were at high risk. The AUC for BAR values was 0.757 (75.7%), and this was statistically significant for determining cutoff values, with a cutoff value of >4.60 (p","PeriodicalId":10748,"journal":{"name":"Cukurova Medical Journal","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136277456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose This study aimed to compare the impact of maltreatment on the subtype, comorbidity, sociodemographic characteristics, and psychometric characteristics of attention deficit hyperactivity disorder (ADHD).
Materials and Methods: The study participants included 150 treatment-naïve children with ADHD with (n=75) and without (n=75) a history of maltreatment by parents. A sociodemographic form, the Conners Parent Rating Scale (CPRS), the Conners Teacher Rating Scale (CTRS), the Family Assessment Device (FAD), and the Stroop Form were applied.
Results: Earlier referral, peer discord, and lower parental age were frequent in the maltreated group, while the maternal employment rates were significantly lower. ADHD-combined type and comorbid oppositional defiant disorder were significantly higher in the maltreated group. The CPRS and FAD scores were also significantly higher).
Conclusion: A higher incidence of destructive behavioral patterns may increase the risk of maltreatment. Families of children with hyperactivity and defiant characteristics may have difficulties in managing behavioral problems and may exhibit domestic violence, with the Multidisciplinary approaches, including parental education programs and social investigation, should be considered.
{"title":"Dikkat eksikliği hiperaktivite bozukluğu olgularında kötü muamelenin belirti düzeyine etkisi","authors":"İpek SUZER GAMLİ, Ayşegül YOLGA TAHİROĞLU","doi":"10.17826/cumj.1309521","DOIUrl":"https://doi.org/10.17826/cumj.1309521","url":null,"abstract":"Purpose This study aimed to compare the impact of maltreatment on the subtype, comorbidity, sociodemographic characteristics, and psychometric characteristics of attention deficit hyperactivity disorder (ADHD).
 Materials and Methods: The study participants included 150 treatment-naïve children with ADHD with (n=75) and without (n=75) a history of maltreatment by parents. A sociodemographic form, the Conners Parent Rating Scale (CPRS), the Conners Teacher Rating Scale (CTRS), the Family Assessment Device (FAD), and the Stroop Form were applied.
 Results: Earlier referral, peer discord, and lower parental age were frequent in the maltreated group, while the maternal employment rates were significantly lower. ADHD-combined type and comorbid oppositional defiant disorder were significantly higher in the maltreated group. The CPRS and FAD scores were also significantly higher).
 Conclusion: A higher incidence of destructive behavioral patterns may increase the risk of maltreatment. Families of children with hyperactivity and defiant characteristics may have difficulties in managing behavioral problems and may exhibit domestic violence, with the Multidisciplinary approaches, including parental education programs and social investigation, should be considered.","PeriodicalId":10748,"journal":{"name":"Cukurova Medical Journal","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136277582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: Antimicrobial resistance is a silent pandemic. In this study, it was aimed to determine the distribution and resistance trends of Staphylococcus aureus (S. aureus), Enterococcus faecium (E. faecium) and Enterococcus faecalis (E. faecalis) isolates, which are among the priority pathogens of the World Health Organization in bloodstream infections.
Materials and Methods: This was a retrospective study conducted between January 1, 2021 and March 31, 2023. The blood cultures (n=1261), of which microbiologically tested by using an automated system, were screened in the relevant period via laboratory information system.
Results: Of the total 941 isolates, 51.9% were S. aureus (n=488), 22.9% were E. faecalis (n=216), and 25.2% were E. faecium (n=237). Of the patients, 89.1% were inpatients (n=838), and 10.9% were outpatients (n=103). The most of patients were hospitalized in internal medicine departments (53.3%) and in intensive care units (35%). Among S. aureus isolates, the resistance rate to benzylpenicillin was 93.8%, to methicillin 44.3%, to teicoplanin 3.7%, and to linezolid 0.4%. Vancomycin and tigecycline resistances were not detected. Of the E. faecalis isolates, 5.5% were resistant to ampicillin, 3.3% to vancomycin, 3.2% to linezolid, and 0.7% to tigecycline. The resistance rates for E. faecium strains were 90.9% for ampicillin, 28.7% for vancomycin, 17.7% for tigecycline, 4.3% for linezolid, and 0.8% for teicoplanin. When the susceptibilities of all three bacteria were compared, a statistically significant difference was found between teicoplanin, vancomycin, tigecycline and linezolid susceptibilities. The methicillin resistance was higher in internal medicine and intensive care units. The levofloxacin and vancomycin resistance were more prevalent in intensive care units.
Conclusion: MRSA (44.3%), vancomycin (28.7%) and tigecycline (17.7%) resistant E. faecium rates are well above the national data. The epidemiology on resistance trends, which will guide clinicians in the management of bloodstream infections, should be carried out periodically.
{"title":"Prevalence and resistance trends of Gram positive cocci Staphylococcus aereus and Enterococcus spp. in a tertiary care hospital","authors":"Hatice Hale GÜMÜŞ","doi":"10.17826/cumj.1350843","DOIUrl":"https://doi.org/10.17826/cumj.1350843","url":null,"abstract":"Purpose: Antimicrobial resistance is a silent pandemic. In this study, it was aimed to determine the distribution and resistance trends of Staphylococcus aureus (S. aureus), Enterococcus faecium (E. faecium) and Enterococcus faecalis (E. faecalis) isolates, which are among the priority pathogens of the World Health Organization in bloodstream infections. 
 Materials and Methods: This was a retrospective study conducted between January 1, 2021 and March 31, 2023. The blood cultures (n=1261), of which microbiologically tested by using an automated system, were screened in the relevant period via laboratory information system. 
 Results: Of the total 941 isolates, 51.9% were S. aureus (n=488), 22.9% were E. faecalis (n=216), and 25.2% were E. faecium (n=237). Of the patients, 89.1% were inpatients (n=838), and 10.9% were outpatients (n=103). The most of patients were hospitalized in internal medicine departments (53.3%) and in intensive care units (35%). Among S. aureus isolates, the resistance rate to benzylpenicillin was 93.8%, to methicillin 44.3%, to teicoplanin 3.7%, and to linezolid 0.4%. Vancomycin and tigecycline resistances were not detected. Of the E. faecalis isolates, 5.5% were resistant to ampicillin, 3.3% to vancomycin, 3.2% to linezolid, and 0.7% to tigecycline. The resistance rates for E. faecium strains were 90.9% for ampicillin, 28.7% for vancomycin, 17.7% for tigecycline, 4.3% for linezolid, and 0.8% for teicoplanin. When the susceptibilities of all three bacteria were compared, a statistically significant difference was found between teicoplanin, vancomycin, tigecycline and linezolid susceptibilities. The methicillin resistance was higher in internal medicine and intensive care units. The levofloxacin and vancomycin resistance were more prevalent in intensive care units. 
 Conclusion: MRSA (44.3%), vancomycin (28.7%) and tigecycline (17.7%) resistant E. faecium rates are well above the national data. The epidemiology on resistance trends, which will guide clinicians in the management of bloodstream infections, should be carried out periodically.","PeriodicalId":10748,"journal":{"name":"Cukurova Medical Journal","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136277663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: This study was designed to find an answer to the question, "Is it beneficial to use pomegranate (POM) and tangeretin (TAN) separately or in combination, for the prevention of acute gastric ulcer?".
Materials and Methods: The gastroprotective effect of tangeretin and pomegranate was determined by measuring the levels of the selected inflammatory cytokines [tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), IL-1β and IL-10], lipid peroxides, and enzymatic activities of antioxidants in gastric tissue samples.
Results: When all groups are written as control, gastric ulcer, POM+EtOH, TAN+EtOH and POM+TAN+EtOH, respectively; IL-1β cytokine levels were measured as 0.147, 0.24, 0.228, 0.195 and 0.182 pg/g protein. IL-6 levels; 16,857, 25,923, 19,797, 18,838 and 17,896 pg/mg protein. TNF-α levels were 39,916, 49.97, 44,678, 41,673 and 40,844 pg/mg protein. Finally, IL-10 levels were measured as 33,496, 28,071, 29,693, 30,073 and 30,008 pg/mg protein. SOD activities were determined as 18,038, 13,731, 15,506, 14,439, and 15,943. CAT activities were 674,638, 639,964, 673,382, 664,691, and 671,203. Protein carbonyl levels were measured as 26,799, 40,30, 33,052, 34,579 and 32,79. Finally, MDA levels were found as 5,239, 9,814, 6,695, 5,771 and 5,836. Briefly, POM and TAN showed their antioxidant functions by decreasing the levels of malondialdehyde (MDA), and protein carbonyl and increasing the activity of superoxide dismutase (SOD) and catalase (CAT). And also, these protective agents exhibited their anti-inflammatory functions by decreasing the content of TNF-α, IL-6, and IL-1β, and increasing the IL-10 levels.
Conclusion: Tangeretin and pomegrenate have a potential gastroprotective effect against ethanol-induced acute gastric ulcer and that the combined treatment is more beneficial than the effect of POM or TAN alone. In addition, this effect is thought to be due to the fact that both selected flavonoids can show a synergistic effect, reducing the levels of inflammation parameters and increasing antioxidant levels.
{"title":"The protective effect of tangeretin and pomegranate separately and in combination on ethanol-induced acute gastric ulcer model","authors":"Solmaz SUSAM, Nevin İLHAN, Fatma TEDİK, Buket BERK, Ayşe Şebnem İLHAN","doi":"10.17826/cumj.1314757","DOIUrl":"https://doi.org/10.17826/cumj.1314757","url":null,"abstract":"Purpose: This study was designed to find an answer to the question, \"Is it beneficial to use pomegranate (POM) and tangeretin (TAN) separately or in combination, for the prevention of acute gastric ulcer?\". 
 Materials and Methods: The gastroprotective effect of tangeretin and pomegranate was determined by measuring the levels of the selected inflammatory cytokines [tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), IL-1β and IL-10], lipid peroxides, and enzymatic activities of antioxidants in gastric tissue samples.
 Results: When all groups are written as control, gastric ulcer, POM+EtOH, TAN+EtOH and POM+TAN+EtOH, respectively; IL-1β cytokine levels were measured as 0.147, 0.24, 0.228, 0.195 and 0.182 pg/g protein. IL-6 levels; 16,857, 25,923, 19,797, 18,838 and 17,896 pg/mg protein. TNF-α levels were 39,916, 49.97, 44,678, 41,673 and 40,844 pg/mg protein. Finally, IL-10 levels were measured as 33,496, 28,071, 29,693, 30,073 and 30,008 pg/mg protein. SOD activities were determined as 18,038, 13,731, 15,506, 14,439, and 15,943. CAT activities were 674,638, 639,964, 673,382, 664,691, and 671,203. Protein carbonyl levels were measured as 26,799, 40,30, 33,052, 34,579 and 32,79. Finally, MDA levels were found as 5,239, 9,814, 6,695, 5,771 and 5,836. Briefly, POM and TAN showed their antioxidant functions by decreasing the levels of malondialdehyde (MDA), and protein carbonyl and increasing the activity of superoxide dismutase (SOD) and catalase (CAT). And also, these protective agents exhibited their anti-inflammatory functions by decreasing the content of TNF-α, IL-6, and IL-1β, and increasing the IL-10 levels. 
 Conclusion: Tangeretin and pomegrenate have a potential gastroprotective effect against ethanol-induced acute gastric ulcer and that the combined treatment is more beneficial than the effect of POM or TAN alone. In addition, this effect is thought to be due to the fact that both selected flavonoids can show a synergistic effect, reducing the levels of inflammation parameters and increasing antioxidant levels.","PeriodicalId":10748,"journal":{"name":"Cukurova Medical Journal","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136277840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: This study investigated the long-term clinical and demographic characteristics of multiple sclerosis (MS) patients to predict disease prognosis.
Materials and Methods: Two hundred and seventy-five MS patients diagnosed using the Poser or McDonald criteria were retrospectively analyzed. They were categorized based on their Expanded Disability Status Scale (EDSS) scores: below 4 (group 1) and 4 or above (group 2).
Results: The average patient age was 55.45 ± 9.63 years, with a disease duration of 26.76 ± 6.08 years. The initial EDSS scores increased from 2.56 ± 2.36 to 4.23 ± 1.8 after 20 years. Of the patients, 69.1% had EDSS scores of 4 or higher after 20 years. Notably, patients with supratentorial and spinal cord involvement at onset had higher EDSS scores. Logistic regression analysis revealed that a higher initial EDSS score, no full recovery after the first attack, and a longer duration between attacks were associated with a higher risk of an EDSS score of 4 or above.
Conclusion: Thisr study shows that an increase in the initial EDSS score is predictive of long-term disability in patients with MS. Having information on long-term, real-life data in MS is highly valuable in terms of understanding the course of the disease, its monitoring, and treatment selection.
{"title":"Multipl sklerozda uzun dönem yeti yitimi: 20 yıllık uzunlamasına bir çalışma","authors":"Sena Destan BÜNÜL","doi":"10.17826/cumj.1335021","DOIUrl":"https://doi.org/10.17826/cumj.1335021","url":null,"abstract":"Purpose: This study investigated the long-term clinical and demographic characteristics of multiple sclerosis (MS) patients to predict disease prognosis.
 Materials and Methods: Two hundred and seventy-five MS patients diagnosed using the Poser or McDonald criteria were retrospectively analyzed. They were categorized based on their Expanded Disability Status Scale (EDSS) scores: below 4 (group 1) and 4 or above (group 2).
 Results: The average patient age was 55.45 ± 9.63 years, with a disease duration of 26.76 ± 6.08 years. The initial EDSS scores increased from 2.56 ± 2.36 to 4.23 ± 1.8 after 20 years. Of the patients, 69.1% had EDSS scores of 4 or higher after 20 years. Notably, patients with supratentorial and spinal cord involvement at onset had higher EDSS scores. Logistic regression analysis revealed that a higher initial EDSS score, no full recovery after the first attack, and a longer duration between attacks were associated with a higher risk of an EDSS score of 4 or above. 
 Conclusion: Thisr study shows that an increase in the initial EDSS score is predictive of long-term disability in patients with MS. Having information on long-term, real-life data in MS is highly valuable in terms of understanding the course of the disease, its monitoring, and treatment selection.","PeriodicalId":10748,"journal":{"name":"Cukurova Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136276532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ferhat Can PİŞKİN, Fulya ODABAŞ, Ulcaz Perihan AKSOYDAN, Gamze AKKUŞ
Purpose: This study aimed to explore the impact of continuous autonomous cortisol secretion on visceral (VAT), abdominal subcutaneous (SAT) adipose tissue, and total body fat.
Materials and Methods: A total of 57 patients (36 female, 21 male) with adrenal masses, referred to our single center, were included in this study. Among them, 31 patients had adrenal cortical carcinoma (ACS) and 26 had nonfunctional adrenal mass (NFAM). Hormonal evaluation was conducted for all patients. Measurements of total, visceral, and subcutaneous adipose tissue were performed using 3.0 T magnetic resonance imaging (Ingenia, Philips Medical Systems, Best, The Netherlands).
Results: Mean age, gender distribution, and body mass index (BMI) were comparable between patients with ACS and NFAM. Patients with ACS exhibited higher volumes of both total (422.1±131.3 vs. 346.2±86.0 cm3) and visceral adipose tissue (199.9±77.3 vs. 160.6±60.8 cm3) compared to those with NFAM. Incidence rates of diabetes mellitus and hepatosteatosis were similar in both groups. Subcutaneous adipose tissue volumes, visceral-to-subcutaneous ratio, and visceral-to-total fat ratio showed no significant differences between the two groups.
Conclusion: Patients with ACS demonstrated increased total and visceral fat tissue volumes compared to NFAM patients matched for gender, age, and BMI. This observation may elucidate the potential influence of continuous mild autonomous cortisol secretion in ACS patients. Such findings could serve as indicators of heightened cardiovascular risk among ACS patients.
目的:本研究旨在探讨持续自主皮质醇分泌对内脏(VAT)、腹部皮下(SAT)脂肪组织和全身脂肪的影响。
材料与方法:本研究共纳入57例肾上腺肿物患者，其中女性36例，男性21例。其中，肾上腺皮质癌(ACS) 31例，非功能性肾上腺肿块(NFAM) 26例。所有患者均进行激素评估。使用3.0 T磁共振成像(Ingenia, Philips Medical Systems, Best, The Netherlands)测量总脂肪组织、内脏和皮下脂肪组织。
结果:ACS和NFAM患者的平均年龄、性别分布和体重指数(BMI)具有可比性。与NFAM患者相比，ACS患者表现出更高的总体积(422.1±131.3比346.2±86.0 cm3)和内脏脂肪组织(199.9±77.3比160.6±60.8 cm3)。两组患者糖尿病和肝纤维化的发生率相似。皮下脂肪组织体积、内脏与皮下比值、内脏与总脂肪比值两组间无显著差异。
结论:与性别、年龄和BMI相匹配的NFAM患者相比，ACS患者表现出总脂肪和内脏脂肪组织体积的增加。这一观察结果可能阐明ACS患者持续轻度自主皮质醇分泌的潜在影响。这些发现可以作为ACS患者心血管风险增加的指标。
{"title":"Otonom kortizol sekresyonu olan hastalarda ve fonksiyonel olmayan adrenal kitleleri olan hastalarda viseral yağ dokusunun karşılaştırılması","authors":"Ferhat Can PİŞKİN, Fulya ODABAŞ, Ulcaz Perihan AKSOYDAN, Gamze AKKUŞ","doi":"10.17826/cumj.1319639","DOIUrl":"https://doi.org/10.17826/cumj.1319639","url":null,"abstract":"Purpose: This study aimed to explore the impact of continuous autonomous cortisol secretion on visceral (VAT), abdominal subcutaneous (SAT) adipose tissue, and total body fat.
 Materials and Methods: A total of 57 patients (36 female, 21 male) with adrenal masses, referred to our single center, were included in this study. Among them, 31 patients had adrenal cortical carcinoma (ACS) and 26 had nonfunctional adrenal mass (NFAM). Hormonal evaluation was conducted for all patients. Measurements of total, visceral, and subcutaneous adipose tissue were performed using 3.0 T magnetic resonance imaging (Ingenia, Philips Medical Systems, Best, The Netherlands).
 Results: Mean age, gender distribution, and body mass index (BMI) were comparable between patients with ACS and NFAM. Patients with ACS exhibited higher volumes of both total (422.1±131.3 vs. 346.2±86.0 cm3) and visceral adipose tissue (199.9±77.3 vs. 160.6±60.8 cm3) compared to those with NFAM. Incidence rates of diabetes mellitus and hepatosteatosis were similar in both groups. Subcutaneous adipose tissue volumes, visceral-to-subcutaneous ratio, and visceral-to-total fat ratio showed no significant differences between the two groups.
 Conclusion: Patients with ACS demonstrated increased total and visceral fat tissue volumes compared to NFAM patients matched for gender, age, and BMI. This observation may elucidate the potential influence of continuous mild autonomous cortisol secretion in ACS patients. Such findings could serve as indicators of heightened cardiovascular risk among ACS patients.","PeriodicalId":10748,"journal":{"name":"Cukurova Medical Journal","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136276535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: In this study, we investigated the relationship between integrated pulmonary index and patients’ demographic data, surgical characteristics, postoperative complications, blood gas analysis, and hemodynamic values after thoracic surgery.
Materials and Methods: A total of 97 patients scheduled for elective thoracic surgery were included in this study. After surgery, integrated pulmonary index monitoring was performed for all patients in the post-anesthetic care unit. Patients’ characteristics, postoperative hemodynamic values, arterial blood gas analysis, length of hospital stay, postoperative complications, duration of anesthesia, and duration of surgery were recorded. Their correlations with postoperative integrated pulmonary index scores at 30 minutes, 1 hour, and 2 hours were investigated.
Results: Patients’ demographic data and surgical characteristics did not affect integrated pulmonary index scores. No significant correlation was found between integrated pulmonary index scores and duration of anesthesia, duration of surgery, postoperative complications, or length of hospital stay. However, there was a correlation between postoperative hemodynamic values, arterial blood gas analysis and integrated pulmonary index score.
Conclusion: Integrated pulmonary index monitoring is a bedside and non-invasive method that displays multiple parameters on a single screen, corraletes with arterial blood gas analysis and hemodynamic values. Therefore, it may provide advantages in early follow-up of thoracic surgery patients. However, multicenter, randomized controlled studies with a larger number of patients are needed to investigate the efficacy of integrated pulmonary index in patients undergoing thoracic surgery.
{"title":"Is there any correlation between integrated pulmonary index and thoracic surgery patients’ follow-up data? a prospective, observational study","authors":"Zaid ABDULKAREM, Mediha TÜRKTAN, Ersel GÜLEÇ, Zehra HATİPOĞLU, Hulya BİNOKAY, Dilek ÖZCENGİZ","doi":"10.17826/cumj.1322052","DOIUrl":"https://doi.org/10.17826/cumj.1322052","url":null,"abstract":"Purpose: In this study, we investigated the relationship between integrated pulmonary index and patients’ demographic data, surgical characteristics, postoperative complications, blood gas analysis, and hemodynamic values after thoracic surgery.
 Materials and Methods: A total of 97 patients scheduled for elective thoracic surgery were included in this study. After surgery, integrated pulmonary index monitoring was performed for all patients in the post-anesthetic care unit. Patients’ characteristics, postoperative hemodynamic values, arterial blood gas analysis, length of hospital stay, postoperative complications, duration of anesthesia, and duration of surgery were recorded. Their correlations with postoperative integrated pulmonary index scores at 30 minutes, 1 hour, and 2 hours were investigated. 
 Results: Patients’ demographic data and surgical characteristics did not affect integrated pulmonary index scores. No significant correlation was found between integrated pulmonary index scores and duration of anesthesia, duration of surgery, postoperative complications, or length of hospital stay. However, there was a correlation between postoperative hemodynamic values, arterial blood gas analysis and integrated pulmonary index score. 
 Conclusion: Integrated pulmonary index monitoring is a bedside and non-invasive method that displays multiple parameters on a single screen, corraletes with arterial blood gas analysis and hemodynamic values. Therefore, it may provide advantages in early follow-up of thoracic surgery patients. However, multicenter, randomized controlled studies with a larger number of patients are needed to investigate the efficacy of integrated pulmonary index in patients undergoing thoracic surgery.","PeriodicalId":10748,"journal":{"name":"Cukurova Medical Journal","volume":"2013 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136277459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: This study aimed to investigate the relationship of sleep quality and insomnia with metabolic/anthropometric parameters in elderly individuals.
Materials and Methods: This cross-sectional study was conducted with 474 elderly individuals. Their fasting blood glucose, haemoglobin A1c, total cholesterol, triglycerides, low-density lipoprotein, high-density lipoprotein, cortisol, C-reactive protein, weight, waist circumference, waist-to-hip ratio, skeletal muscle mass, body fat mass and body mass index were measured. Their sleep quality was evaluated using the Pittsburgh Sleep Quality Index, and insomnia was assessed using the Insomnia Severity Index.
Results: The mean age of the 474 elderly individuals included in the study was 71.02±4.90 years. Poor sleep quality prevalence was found to be 71.1% among the elderly participants and the prevalence of mild to moderate insomnia was 55.1%. The sleep quality score was positively correlated with the postprandial blood glucose level (r=0.121, p
目的:探讨老年人睡眠质量和失眠与代谢/人体测量参数的关系。
材料与方法:对474名老年人进行横断面研究。测量他们的空腹血糖、血红蛋白A1c、总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白、皮质醇、c反应蛋白、体重、腰围、腰臀比、骨骼肌质量、体脂质量和体重指数。使用匹兹堡睡眠质量指数评估他们的睡眠质量，使用失眠症严重程度指数评估他们的失眠症。结果:纳入研究的474名老年人的平均年龄为71.02±4.90岁。老年人睡眠质量差的患病率为71.1%，轻度至中度失眠的患病率为55.1%。睡眠质量评分与餐后血糖水平呈正相关(r=0.121, p
{"title":"Effects of sleep quality and insomnia severity on metabolic and anthropometric parameters in elderly individuals","authors":"Burak METE, Lezzan KESKİN","doi":"10.17826/cumj.1309925","DOIUrl":"https://doi.org/10.17826/cumj.1309925","url":null,"abstract":"Purpose: This study aimed to investigate the relationship of sleep quality and insomnia with metabolic/anthropometric parameters in elderly individuals.
 Materials and Methods: This cross-sectional study was conducted with 474 elderly individuals. Their fasting blood glucose, haemoglobin A1c, total cholesterol, triglycerides, low-density lipoprotein, high-density lipoprotein, cortisol, C-reactive protein, weight, waist circumference, waist-to-hip ratio, skeletal muscle mass, body fat mass and body mass index were measured. Their sleep quality was evaluated using the Pittsburgh Sleep Quality Index, and insomnia was assessed using the Insomnia Severity Index.
 Results: The mean age of the 474 elderly individuals included in the study was 71.02±4.90 years. Poor sleep quality prevalence was found to be 71.1% among the elderly participants and the prevalence of mild to moderate insomnia was 55.1%. The sleep quality score was positively correlated with the postprandial blood glucose level (r=0.121, p","PeriodicalId":10748,"journal":{"name":"Cukurova Medical Journal","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136277580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Concurrence of medulloblastoma and Chiari deformity (type-1) in a pediatric patient is extremely rarely seen. 10 years old girl. She had first complained of nausea, abdominal pain, and vomiting. She had a mild headache for three days. Computed tomography was taken. There were sequelae related to her previous illness and noticed the appearance of the left cerebellar tonsils down to the foramen magnum level and mild prominence in the third ventricle. Cranial imaging was performed with magnetic resonance imaging. There was a lesion as a solid mass, about 60 mm sized in the level right cerebellar, a cerebellar tonsil hernia (11 mm), and ventricular dilatation in magnetic resonance imaging. Histologically, the lesion was a classic type of medulloblastoma. The coexistence of two diseases may occur in the same patient. Magnetic resonance imaging, which indicates the craniovertebral junction can be used singly.Because MRG is the first method to be selected for diagnosis.
{"title":"Pediatrik bir hastada eş zamanlı medulloblastoma ve Chiari Tip-I deformitesi","authors":"İlknur SÜRÜCÜ KARA, Tayfun ÇAKIR","doi":"10.17826/cumj.1315981","DOIUrl":"https://doi.org/10.17826/cumj.1315981","url":null,"abstract":"Concurrence of medulloblastoma and Chiari deformity (type-1) in a pediatric patient is extremely rarely seen. 10 years old girl. She had first complained of nausea, abdominal pain, and vomiting. She had a mild headache for three days. Computed tomography was taken. There were sequelae related to her previous illness and noticed the appearance of the left cerebellar tonsils down to the foramen magnum level and mild prominence in the third ventricle. Cranial imaging was performed with magnetic resonance imaging. There was a lesion as a solid mass, about 60 mm sized in the level right cerebellar, a cerebellar tonsil hernia (11 mm), and ventricular dilatation in magnetic resonance imaging. Histologically, the lesion was a classic type of medulloblastoma. The coexistence of two diseases may occur in the same patient. Magnetic resonance imaging, which indicates the craniovertebral junction can be used singly.Because MRG is the first method to be selected for diagnosis.","PeriodicalId":10748,"journal":{"name":"Cukurova Medical Journal","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136277653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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