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KNOWLEDGE LEVELS, ATTITUDES, AND BEHAVIORS OF PREGNANTS ABOUT PRENATAL SCREENING TESTS: A SECTIONAL STUDY 知识水平,态度和行为的孕妇产前筛查试验:一项分段研究
Pub Date : 2023-09-11 DOI: 10.7197/cmj.1344696
Seher KARAHAN, Dilay KARADEMİR, Ezgi AĞADAYI
Aim: To determine the knowledge levels, attitudes, and behaviors of pregnant women who come to the obstetrics clinic in a university hospital about prenatal screening tests. Method: It is a descriptive cross-sectional study. The population consists of approximately 900 pregnant women who are 28 weeks and beyond, who applied to …….. University Faculty of Medicine, Obstetrics and Gynecology outpatient clinic between October-December 2021. The research questionnaire was applied face to face to those who agreed to participate in the study. The data form consisting of 21 questions included questions about the descriptive characteristics and obstetric histories of pregnant women. Results: 254 people participated. The mean gestational week of the participants was 34.9±3.9 (min:28-max:41). The most common screening tests were detailed ultrasound (80.7%) and double screening tests. Those who received information from their obstetrician had a significantly higher rate of having the test. When the participants' knowledge scores about prenatal screening tests are evaluated, respectively; Detailed ultrasound knowledge score was 5.6±0.9, Double test 5.0±1.3, Oral Glucose Tolerance Test 4.8±1.1, and Triple test 4.7±1.2(min:2-max:7). When the reasons for not having prenatal screening tests were questioned, the most common answer for all screening tests was "I don't think the test is necessary". For the OGTT, the second most common reason for not having it done was because they heard from the media that the test was harmful. The fact that the pregnant women had a double and triple screening, went to regular controls and had a high double-triple test knowledge score had a significant effect. Amniocentesis was recommended for 3.5% of the pregnant women based on prenatal test results, but none of them had amniocentesis. In case of unfavorable prenatal test results, the majority of pregnant women were considering continuing the pregnancy. Conclusion: In this study, we found that the rate of testing increased with the increasing knowledge level of pregnant women and physician counseling. In this context, health professionals should provide women with the necessary education about screening and diagnostic tests to enable them to make informed decisions.
目的:了解到某大学附属医院产科门诊就诊的孕妇对产前筛查的知识水平、态度和行为。 方法:采用描述性横断面研究。人口由大约900名28周及以上的孕妇组成,她们申请了........大学医学院妇产科门诊2021年10月- 12月。研究问卷是面对面发给那些同意参加研究的人的。数据表由21个问题组成,包括孕妇的描述性特征和产科史。 结果:254人参与。参与者的平均妊娠周为34.9±3.9 (min:28-max:41)。最常见的筛查检查是详细超声检查(80.7%)和双重筛查。那些从产科医生那里得到信息的人接受检测的几率要高得多。当参与者产前筛查测试的知识得分分别评估;详细超声知识得分为5.6±0.9分,双重试验5.0±1.3分,口服糖耐量试验4.8±1.1分,三重试验4.7±1.2分(min:2-max:7分)。当问及不进行产前筛查检查的原因时,对所有筛查检查最常见的回答是“我认为没有必要进行筛查”。对于OGTT来说,第二个最常见的原因是他们从媒体那里听说这项测试是有害的。孕妇进行了双重和三重筛查,进入常规对照,并有较高的双重和三重测试知识得分,这一事实有显著的影响。根据产前检查结果,建议3.5%的孕妇进行羊膜穿刺术,但没有人进行羊膜穿刺术。在产前检查结果不理想的情况下,大多数孕妇考虑继续妊娠。 结论:在本研究中,我们发现随着孕妇知识水平的提高和医师咨询的增加,检测率呈上升趋势。在这方面,保健专业人员应向妇女提供有关筛查和诊断测试的必要教育,使她们能够作出知情的决定。
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 Method: It is a descriptive cross-sectional study. The population consists of approximately 900 pregnant women who are 28 weeks and beyond, who applied to …….. University Faculty of Medicine, Obstetrics and Gynecology outpatient clinic between October-December 2021. The research questionnaire was applied face to face to those who agreed to participate in the study. The data form consisting of 21 questions included questions about the descriptive characteristics and obstetric histories of pregnant women.
 Results: 254 people participated. The mean gestational week of the participants was 34.9±3.9 (min:28-max:41). The most common screening tests were detailed ultrasound (80.7%) and double screening tests. Those who received information from their obstetrician had a significantly higher rate of having the test. When the participants' knowledge scores about prenatal screening tests are evaluated, respectively; Detailed ultrasound knowledge score was 5.6±0.9, Double test 5.0±1.3, Oral Glucose Tolerance Test 4.8±1.1, and Triple test 4.7±1.2(min:2-max:7). When the reasons for not having prenatal screening tests were questioned, the most common answer for all screening tests was \"I don't think the test is necessary\". For the OGTT, the second most common reason for not having it done was because they heard from the media that the test was harmful. The fact that the pregnant women had a double and triple screening, went to regular controls and had a high double-triple test knowledge score had a significant effect. Amniocentesis was recommended for 3.5% of the pregnant women based on prenatal test results, but none of them had amniocentesis. In case of unfavorable prenatal test results, the majority of pregnant women were considering continuing the pregnancy.
 Conclusion: In this study, we found that the rate of testing increased with the increasing knowledge level of pregnant women and physician counseling. In this context, health professionals should provide women with the necessary education about screening and diagnostic tests to enable them to make informed decisions.","PeriodicalId":10750,"journal":{"name":"Cumhuriyet medical journal","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136025529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TYPE 2 DIABETES MELLITUS SCREENING: THE SAMPLE OF SİVAS 2型糖尿病筛查:以sİvas为样本
Pub Date : 2023-09-11 DOI: 10.7197/cmj.1338902
Seher KARAHAN
ABSTRACT Objective: The aim of the study is to screen for Type 2 Diabetes Mellitus (DM), to determine the risk of DM and to evaluate the factors affecting it. Method: It is a descriptive study. The population of the research consisted of people over the age of 18 living in Sivas who were not diagnosed with diabetes. The sample of the research consisted of individuals over the age of 18 who did not have diabetes and participated in the event, which was organized as part of the 14 November 2022 “World Diabetes Day” event, which continued between 08.00-17.00. In order to reach the universe, a stand was set up in the city center in the square where the people are concentrated. Capillary blood glucose measurement, a questionnaire including height, weight, demographic characteristics and Finnish Diabetes Risk Questionnaire (FINDRISK) were applied to the patients. FINDRISK consists of 8 questions. It determines an individual's risk of developing diabetes in the next ten years. Results are shown as frequencies, mean±standard deviation. Pearson correlation analysis, Student-T test and One way ANOVA test were applied. P
摘要# x0D;目的:本研究的目的是筛查2型糖尿病(DM),确定患DM的风险并评价其影响因素。方法:采用描述性研究。该研究的人群包括居住在锡瓦斯的18岁以上未被诊断患有糖尿病的人。该研究样本由18岁以上无糖尿病的个人组成,他们参加了该活动,该活动是作为2022年11月14日“世界糖尿病日”活动的一部分组织的,活动持续时间为08:00 - 17:00。为了到达宇宙,在市中心人群聚集的广场上设立了一个展台。采用毛细管血糖测量、身高、体重、人口统计学特征问卷和芬兰糖尿病风险问卷(FINDRISK)。FINDRISK由8个问题组成。它决定了一个人在未来十年内患糖尿病的风险。结果以频率表示,平均值±标准差。采用Pearson相关分析、Student-T检验和单因素方差分析。P
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 Objective: The aim of the study is to screen for Type 2 Diabetes Mellitus (DM), to determine the risk of DM and to evaluate the factors affecting it.
 Method: It is a descriptive study. The population of the research consisted of people over the age of 18 living in Sivas who were not diagnosed with diabetes. The sample of the research consisted of individuals over the age of 18 who did not have diabetes and participated in the event, which was organized as part of the 14 November 2022 “World Diabetes Day” event, which continued between 08.00-17.00. In order to reach the universe, a stand was set up in the city center in the square where the people are concentrated. Capillary blood glucose measurement, a questionnaire including height, weight, demographic characteristics and Finnish Diabetes Risk Questionnaire (FINDRISK) were applied to the patients. FINDRISK consists of 8 questions. It determines an individual's risk of developing diabetes in the next ten years. Results are shown as frequencies, mean±standard deviation. Pearson correlation analysis, Student-T test and One way ANOVA test were applied. P","PeriodicalId":10750,"journal":{"name":"Cumhuriyet medical journal","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136025530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Vitamin D and Acute Phase Proteins in the Diagnosis of Hyperemesis Gravidarum 维生素D和急性期蛋白在妊娠剧吐诊断中的作用
Pub Date : 2023-09-11 DOI: 10.7197/cmj.1347700
Dilay KARADEMİR, Nazan YURTÇU
Objective: Hyperemesis gravidarum (HG) has severe and dramatic consequences, and the cause of this severe disease has not yet been determined clearly. It is known that hormonal, metabolic, immunological, and inflammatory agents may be effective in their etiology. Our study aimed to investigate the possible role of vitamin D, Lactate Dehydrogenase (LDH), Procalcitonin (PCT), and C- reactive Protein (CRP) in the etiology of HG. Method: In this retrospective study, between June 1, 2021, and January 1, 2022, 110 pregnant women between the ages of 18 and 35 were admitted to the Obstetrics and Gynecology Polyclinic of the Sivas Cumhuriyet University Faculty of Medicine. Fifty-five patients diagnosed with HG were taken as a study group, and fifty-five healthy pregnant women not diagnosed with HG were taken as a control group. Obstetric data and serum vitamin D, LDH, PCT, and CRP values of pregnant women were detected retrospectively. Results: When the groups with and without HG were compared, although the CRP and LDH levels were high in the HG group, they were not statistically significant (p = 0.084, p = 0.546). Vitamin D and PCT were significantly higher in the HG group than in the control group (p = 0.001, p = 0.047). Conclusion: Our study found that vitamin D and PCT levels were high in pregnant women with HG. Further studies with more participants are needed before these inflammatory markers can be used to diagnose HG.
目的:妊娠剧吐(Hyperemesis gravidarum, HG)是一种严重而剧烈的疾病,其病因尚未明确。众所周知,激素、代谢、免疫和炎症因子在其病因中可能是有效的。我们的研究旨在探讨维生素D、乳酸脱氢酶(LDH)、降钙素原(PCT)和C-反应蛋白(CRP)在HG病因学中的可能作用。& # x0D;方法:在这项回顾性研究中,于2021年6月1日至2022年1月1日期间,110名年龄在18至35岁之间的孕妇在锡瓦斯大学医学院妇产科综合诊所就诊。以55例确诊为HG的患者为研究组,55例未确诊为HG的健康孕妇为对照组。回顾性检测孕妇的产科资料及血清维生素D、LDH、PCT、CRP值。& # x0D;& # x0D;结果:HG组与非HG组比较,HG组CRP、LDH水平虽然较高,但差异无统计学意义(p = 0.084, p = 0.546)。HG组维生素D和PCT显著高于对照组(p = 0.001, p = 0.047)。 & # x0D;结论:我们的研究发现,孕妇HG中维生素D和PCT水平较高,在这些炎症标志物用于诊断HG之前,需要更多的参与者进行进一步的研究。
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 Method: In this retrospective study, between June 1, 2021, and January 1, 2022, 110 pregnant women between the ages of 18 and 35 were admitted to the Obstetrics and Gynecology Polyclinic of the Sivas Cumhuriyet University Faculty of Medicine. Fifty-five patients diagnosed with HG were taken as a study group, and fifty-five healthy pregnant women not diagnosed with HG were taken as a control group. Obstetric data and serum vitamin D, LDH, PCT, and CRP values of pregnant women were detected retrospectively. 
 
 Results: When the groups with and without HG were compared, although the CRP and LDH levels were high in the HG group, they were not statistically significant (p = 0.084, p = 0.546). Vitamin D and PCT were significantly higher in the HG group than in the control group (p = 0.001, p = 0.047).
 
 Conclusion: Our study found that vitamin D and PCT levels were high in pregnant women with HG. Further studies with more participants are needed before these inflammatory markers can be used to diagnose HG.","PeriodicalId":10750,"journal":{"name":"Cumhuriyet medical journal","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136025531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does interscalene block increase intracranial pressure? 斜角肌间阻滞会增加颅内压吗?
Pub Date : 2023-06-27 DOI: 10.7197/cmj.1125237
Oğuz Gündoğdu, Onur Avcı
Interscalene brachial plexus (ISB) block is widely used in shoulder and humerus surgeries, especially in patients that have high risk for general anesthesia. Increased intracranial pressure (ICP) is not among the complications of this block because there is no data about this issue in the literature. In this traumatic case report, a patient with headache and with a known meningioma in his right temporo occipital region is gonna have a proximal humerus fracture surgery with ISB block under repetitive optic nerve sheath diameter measurements. The result of this case report can add a unique information to the ISB literature.
斜角肌间臂丛阻滞(ISB)广泛应用于肩关节和肱骨手术,特别是全麻高危患者。颅内压升高(ICP)不属于这种阻滞的并发症,因为文献中没有关于这一问题的数据。在这个创伤性病例报告中,一个头痛的病人在他的右颞枕区有脑膜瘤将在重复测量视神经鞘直径的情况下进行肱骨近端骨折手术。本病例报告的结果可以为ISB文献增加一个独特的信息。
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引用次数: 0
PERIODIC FEVER, APHTHOUS STOMATITIS, PHARYNGITIS, (PFAPA) SYNDROME AND NLRP3 GENE ASSOCIATION 周期性发热、口疮性口炎、咽炎、(pfapa)综合征与nlrp3基因的相关性
Pub Date : 2023-06-25 DOI: 10.7197/cmj.1310396
Gülşah Ünsal
PFAPA syndrome, which also includes aphthous stomatitis, pharyngitis, and adenitis, is the most common type of recurrent fever in children. Usually happens before the age of five. This syndrome is characterized by attacks lasting 3-7 days, recurring every 2-8 weeks with high fever (39 C and above) accompanied by at least one of the signs of aphthous stomatitis, pharyngitis, and/or cervical adenitis. Between attacks, the child is completely healthy.PFAPA is a benign disease that regresses with age. Steroids are used in the treatment of attacks. Colchicine is often preferred in prophylactic treatment. However, if there is no response to medical treatment, surgery (tonsillectomy) can be performed. Genetic and environmental factors are considered in the etiology. Genetic susceptibility concentrated on the genes for Familiar Mediterranean Fever (FMF, MEFV), TNF-Receptor-Associated Periodic Syndrome (TRAPS, gene TNFRF1A), HyperIgDSyndrome (HIDS, gene MVK), and Cryopyrin-Associated Periodic Syndrome (CAPS, gene NLRP3). But its etiology is still unknown.
PFAPA综合征还包括口疮性口炎、咽炎和腺炎,是儿童最常见的复发性发热类型。通常发生在五岁之前。该综合征的特点是发作持续3-7天,每2-8周复发一次,伴有高热(39℃及以上),并伴有口疮性口炎、咽炎和/或宫颈腺炎的至少一种症状。在两次发作之间,孩子完全健康。PFAPA是一种良性疾病,随着年龄的增长而退化。类固醇用于治疗发作。秋水仙碱常用于预防治疗。但是,如果药物治疗无效,可以进行手术(扁桃体切除术)。病因学考虑了遗传和环境因素。遗传易感性主要集中在常见地中海热(FMF, MEFV)、tnf受体相关周期综合征(TRAPS,基因TNFRF1A)、高igd综合征(HIDS,基因MVK)和低温素相关周期综合征(CAPS,基因NLRP3)基因。但其病因尚不清楚。
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引用次数: 0
Did Covid 19 disease increase mesenteric ischemia cases? 新冠肺炎是否增加了肠系膜缺血病例?
Pub Date : 2023-06-25 DOI: 10.7197/cmj.1278581
Hüsnü Çağrı Genç, K. Gemici
İntroduction Covid 19 (C19) disease causes mortal complications due to both respiratory system involvement and extrapulmonary involvement. C19 patients may present with gastrointestinal symptoms such as nausea-vomiting, diarrhea and loss of appetite, as well as serious conditions such as acute mesenteric ischemia. C19 disease is a proinflammatory condition that causes thrombus formation. Material method The first group (G1) was treated with 21 mesenteric ischemia cases operated in the General Surgery Department of Aksaray Training and Research Hospital in approximately two years between March 2020 and February 2022, and the second group (G2), in a two-year period between 2018-2020 before the pandemic, in the same department. The information of 11 mesenteric ischemia cases who underwent surgery were analyzed from the hospital information system. Statistically, the predisposing diseases, demographic data, intestinal lengths removed during the operation, and survival of the patients in both groups were compared. Results When the number of patients who were operated on in G1 and G2 were compared, it was seen that more patients were operated in G1. The probability of mesenteric ischemia in a 24-month period was found to be 0.875 in G1 and 0.458 in G2. These rates were statistically different (p=0.002). When the mean age, length of the removed bowel, and postoperative mortality of both groups were compared, no significant difference was found. Conclusion Although the exact mechanism by which the Covid 19 disease causes mesenteric ischemia is not understood, we observed a statistically significant increase in mesenteric ischemia cases during the pandemic period compared to the pre-pandemic return. Considering the Physiopathology of C19, it is known that the diseases in the body generally occur on the basis of vasculitis. When C19 infection is detected, we recommend anticoagulant treatment for at least 3 months during the infection and for the prevention of other complications related to vasculitis, especially mesenteric ischemia.
İntroduction Covid - 19 (C19)疾病由于呼吸系统受累和肺外受累而导致致命并发症。C19患者可能出现恶心呕吐、腹泻和食欲不振等胃肠道症状,也可能出现急性肠系膜缺血等严重情况。C19疾病是一种引起血栓形成的促炎性疾病。第一组(G1)于2020年3月至2022年2月在阿克萨莱培训与研究医院普外科手术治疗的肠系膜缺血患者21例,第二组(G2)于大流行前的2018-2020年在同一科手术治疗。分析医院信息系统中11例肠系膜缺血手术患者的信息。统计学上比较两组患者的易感疾病、人口学资料、术中切除的肠长及生存率。结果比较G1期和G2期手术患者的数量,G1期手术患者较多。在24个月的时间内,G1发生肠系膜缺血的概率为0.875,G2为0.458。这些比率有统计学差异(p=0.002)。比较两组患者的平均年龄、切除肠段长度和术后死亡率,无显著差异。结论虽然Covid - 19疾病引起肠系膜缺血的确切机制尚不清楚,但我们观察到,与大流行前相比,大流行期间肠系膜缺血病例有统计学意义的增加。考虑到C19的生理病理,我们知道体内的疾病一般是在血管炎的基础上发生的。当检测到C19感染时,我们建议在感染期间至少进行3个月的抗凝治疗,并预防与血管炎相关的其他并发症,特别是肠系膜缺血。
{"title":"Did Covid 19 disease increase mesenteric ischemia cases?","authors":"Hüsnü Çağrı Genç, K. Gemici","doi":"10.7197/cmj.1278581","DOIUrl":"https://doi.org/10.7197/cmj.1278581","url":null,"abstract":"İntroduction \u0000Covid 19 (C19) disease causes mortal complications due to both respiratory system involvement and extrapulmonary involvement. C19 patients may present with gastrointestinal symptoms such as nausea-vomiting, diarrhea and loss of appetite, as well as serious conditions such as acute mesenteric ischemia. C19 disease is a proinflammatory condition that causes thrombus formation. \u0000Material method \u0000The first group (G1) was treated with 21 mesenteric ischemia cases operated in the General Surgery Department of Aksaray Training and Research Hospital in approximately two years between March 2020 and February 2022, and the second group (G2), in a two-year period between 2018-2020 before the pandemic, in the same department. The information of 11 mesenteric ischemia cases who underwent surgery were analyzed from the hospital information system. Statistically, the predisposing diseases, demographic data, intestinal lengths removed during the operation, and survival of the patients in both groups were compared. \u0000Results \u0000When the number of patients who were operated on in G1 and G2 were compared, it was seen that more patients were operated in G1. The probability of mesenteric ischemia in a 24-month period was found to be 0.875 in G1 and 0.458 in G2. These rates were statistically different (p=0.002). When the mean age, length of the removed bowel, and postoperative mortality of both groups were compared, no significant difference was found. \u0000Conclusion \u0000Although the exact mechanism by which the Covid 19 disease causes mesenteric ischemia is not understood, we observed a statistically significant increase in mesenteric ischemia cases during the pandemic period compared to the pre-pandemic return. Considering the Physiopathology of C19, it is known that the diseases in the body generally occur on the basis of vasculitis. When C19 infection is detected, we recommend anticoagulant treatment for at least 3 months during the infection and for the prevention of other complications related to vasculitis, especially mesenteric ischemia.","PeriodicalId":10750,"journal":{"name":"Cumhuriyet medical journal","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85777274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The predictive role of CA- 125 value in early stage endometrioid endometrial cancer CA- 125在早期子宫内膜样癌中的预测作用
Pub Date : 2023-06-24 DOI: 10.7197/cmj.1299893
Begum Kurt, İ. Küçükyıldız, A. Yanik
Objective: We aimed to evaluate the prognostic role of preoperative serum cancer antigen 125 (CA-125) in endometrioid endometrial cancer for determining the cut-off values for clinicopathological factors. Study design: 161 patients were included in the study. The inclusion criteria were histopathological confirmation of endometrioid endometrial cancer and patients with CA-125 levels measured at most ten days before surgery. The association between CA-125 value and clinicopathological variables were analyzed. Receiver operating characteristic curve statistical tests with clinicopathological factors were used to determine the cut-off values and the prognostic role of CA-125. Results: The median value of CA-125 level was 15.4 (3, 2-577) IU/L. These CA-125 cut-off values ranged from 14.30 to 18.67 IU/L (sensitivity 53%– 100%, specificity 30%–59%). The statistical analysis showed a significant relation between CA-125 value and stage and pelvic-paraaortic lymph nodes metastasis. The average life expectancy of patients with CA-125 ≥15.4 was 102.8±5.9 months, whereas that of patients with CA-125
目的:我们旨在评估术前血清癌抗原125 (CA-125)在子宫内膜样子宫内膜癌中的预后作用,以确定临床病理因素的临界值。研究设计:纳入161例患者。纳入标准为子宫内膜样子宫内膜癌的组织病理学确认以及术前最多10天的CA-125水平测定。分析CA-125值与临床病理变量的关系。采用纳入临床病理因素的受试者工作特征曲线统计检验确定CA-125的临界值和预后作用。结果:CA-125水平中位数为15.4 (3,2 -577)IU/L。CA-125临界值范围为14.30至18.67 IU/L(敏感性53% - 100%,特异性30%-59%)。统计分析显示CA-125值与分期及盆腔-主动脉旁淋巴结转移有显著相关性。CA-125≥15.4患者的平均预期寿命为102.8±5.9个月,而CA-125患者的平均预期寿命为102.8±5.9个月
{"title":"The predictive role of CA- 125 value in early stage endometrioid endometrial cancer","authors":"Begum Kurt, İ. Küçükyıldız, A. Yanik","doi":"10.7197/cmj.1299893","DOIUrl":"https://doi.org/10.7197/cmj.1299893","url":null,"abstract":"Objective: We aimed to evaluate the prognostic role of preoperative serum cancer antigen 125 (CA-125) in endometrioid endometrial cancer for determining the cut-off values for clinicopathological factors. \u0000Study design: 161 patients were included in the study. The inclusion criteria were histopathological confirmation of endometrioid endometrial cancer and patients with CA-125 levels measured at most ten days before surgery. The association between CA-125 value and clinicopathological variables were analyzed. Receiver operating characteristic curve statistical tests with clinicopathological factors were used to determine the cut-off values and the prognostic role of CA-125. \u0000Results: The median value of CA-125 level was 15.4 (3, 2-577) IU/L. These CA-125 cut-off values ranged from 14.30 to 18.67 IU/L (sensitivity 53%– 100%, specificity 30%–59%). The statistical analysis showed a significant relation between CA-125 value and stage and pelvic-paraaortic lymph nodes metastasis. The average life expectancy of patients with CA-125 ≥15.4 was 102.8±5.9 months, whereas that of patients with CA-125","PeriodicalId":10750,"journal":{"name":"Cumhuriyet medical journal","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80148521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fine needle aspiration biopsy as a diagnostic method that guides the clinician and affects the treatment in parotid gland masses 细针穿刺活检作为一种指导临床和影响腮腺肿物治疗的诊断方法
Pub Date : 2023-06-24 DOI: 10.7197/cmj.1282269
Adem Bora, Barış Şapci
ABSTRACT Objective: The aim of our study was to determine the specificity and sensitivity criteria of parotid fine needle aspiration biopsy in the diagnosis of parotid gland masses in our instution, and guide the physician by using FNAB before surgery. Study design: Retrospective chart review Methods: Retrospective analysis was conducted by comparing the fine needle aspiration biopsy results of 80 patients with complete data and postoperative histopathological diagnoses of 90 patients who underwent fine needle biopsy in our clinic between 2015 and 2022 and were subsequently operated. Correlation of preoperative FNB results to final surgical pathology was performed and measures of diagnostic accuracy computed. Results: Of all patients, 56.3% were male and 43.7 were female. The mean age was 48 (range 19-87). 56.2% of them were right-sided and 43.8% were left-sided. When the fine needle aspiration biopsies of the patients were examined, 47 were reported as benign (58.8%), 2 as malignant (2.5%), 21 as suspicious (26.3%), and 10 as insufficient (12.5%). Of 80 patients, 34 were diagnosed as pleomorphic adenoma, 14 as whartin tumor, and 7 as sialoadenitis. Conclusion: FNAB is one of the most important diagnostic tools in the diagnosis of parotid gland masses when applied knowing its advantages and given treatment without ignoring the deficiencies. It should be kept in mind that subtyping with FNAB in cases with malignant histopathological diagnosis will reduce the secondary surgical needs of the cases.
摘要目的:探讨本院腮腺细针穿刺活检诊断腮腺肿物的特异性和敏感性标准,指导医师术前应用FNAB。研究设计:回顾性图表回顾方法:回顾性分析2015年至2022年在我诊所行细针穿刺活检并术后行手术的90例患者,对比80例资料完整的细针穿刺活检结果和术后组织病理学诊断。将术前FNB结果与最终手术病理进行相关性分析,并计算诊断准确性。结果:男性占56.3%,女性占43.7。平均年龄48岁(范围19-87岁)。其中右侧占56.2%,左侧占43.8%。经细针穿刺活检,良性47例(58.8%),恶性2例(2.5%),可疑21例(26.3%),不充分10例(12.5%)。80例患者中,34例诊断为多形性腺瘤,14例诊断为whatin瘤,7例诊断为涎腺炎。结论:FNAB是诊断腮腺肿物最重要的诊断工具之一,应用时应了解其优点,不忽视其不足。应该记住,在恶性组织病理学诊断的病例中,用FNAB分型将减少病例的二次手术需求。
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引用次数: 0
EVALUATION OF POSSIBLE COMPLICATIONS OF IRRADIATION OF BLOOD PRODUCTS ON PATIENTS 血液制品辐照对患者可能产生的并发症的评价
Pub Date : 2023-06-24 DOI: 10.7197/cmj.1310755
Hatice Terzi, M. İnanir, Hüseyin Yilmaz, İlkay Yurtsever, M. Sencan
Background: Blood transfusion is a life-saving but high-risk procedure in various medical conditions as it is not a simple fluid infusion but an organ transplant. Although blood transfusions save lives, they may cause serious, life-threatening reactions. Nowadays, the number of reactions has decreased significantly with the reduction of leucocyte content of blood products or their irradiation. Materials and Method: A total of 5582 patients who received irradiated blood products in our hospital between 14/08/2020 and 17/02/2023 were included in the present study. Erythrocyte suspension, platelet apheresis, and pooled platelet suspension were irradiated at doses of 25–30 Gy. Results: A total of 5582 blood products including 4990 erythrocyte suspensions, 282 pooled platelet suspensions, and 310 platelet apheresis were irradiated in the present study. No transfusion-associated Graft Versus Host Disease was identified in any patient included in the present study and there were only mild allergic reactions and febrile non-hemolytic transfusion reactions. Conclusions: Based on the data obtained here from, it was concluded that irradiation of blood products can prevent the highly fatal transfusion-related Graft Versus Host Disease.
背景:输血不是简单的输液,而是器官移植,在各种医疗条件下,输血是一种挽救生命但高风险的手术。虽然输血可以挽救生命,但也可能导致严重的、危及生命的反应。如今,随着血液制品白细胞含量的减少或其辐照程度的降低,反应的次数明显减少。材料与方法:选取2020年8月14日至2023年2月17日在我院接受辐照血液制品治疗的患者5582例为研究对象。红细胞悬浮液、血小板分离液和混合血小板悬浮液以25-30 Gy的剂量照射。结果:本研究共辐照了5582份血液制品,其中红细胞悬浮液4990份,合并血小板悬浮液282份,血小板分离310份。本研究中未发现任何患者存在与输血相关的移植物抗宿主病,仅有轻度过敏反应和发热性非溶血性输血反应。结论:根据本文获得的数据,可以得出结论,血液制品辐照可以预防与输血相关的高致命性移植物抗宿主病。
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引用次数: 0
How does the presence of the pathologist affect the tissue adequacy and what are the factors affecting the pathologist in proficiency assessment, during percutaneous kidney biopsy? 在经皮肾活检中,病理学家的存在如何影响组织的充分性?在熟练程度评估中影响病理学家的因素是什么?
Pub Date : 2023-06-23 DOI: 10.7197/cmj.1316057
Ş. Kaya, Ayhan Senol, Fatma Şule KUTLAR DURSUN, Serkan Çeli̇kgün
Objectives: For optimal histomorphological examination, adequacy of kidney biopsy tissue should be obtained. In this study, the effect of a pathologist informing the radiologist about tissue adequacy during the biopsy procedure on obtaining tissue adequacy was examined. Furthermore, we aimed to determine the criteria that the pathologist considered in determining tissue adequacy and the conditions affecting the decision to increase the number of core biopsies, as these have not been previously examined in the literature. Materials and Methods: Tissues containing less than 10 glomeruli were considered inadequate. In some patients, a pathologist accompanied the radiologist during the procedure. Tissue adequacy ratios and biopsy sample numbers were calculated between the two conditions. In the samples taken with the pathologist, the factors affecting the locality decision of the pathologist (cortex/medulla amount, presence of glomerular pathology(global, segmental, crescentic glomeruli) presence of tubular injury, proteinuria; interstitial inflammation and interstitial fibrosis/tubular atrophy ratios, account of normal glomeruli) were examined. Results: Giving tissue adequacy information during the biopsy procedure had a positive effect on tissue adequacy. The amount of cortex is one of the qualification criteria for the pathologist. The presence of proteinuria and 50% or more inflammation in tissues with sufficient cortex increased the number of biopsy samples. Conclusion: Determination of tissue adequacy during kidney biopsy is an important and necessary method. The amount of cortex is one of the important parameters in tissue adequacy.
目的:为了获得最佳的组织形态学检查,应获得足够的肾活检组织。在这项研究中,病理学家告知放射科医生关于组织充分性在活检过程中对获得组织充分性的影响进行了检查。此外,我们的目的是确定病理学家在确定组织充分性和影响决定增加核心活检数量的条件时所考虑的标准,因为这些在以前的文献中没有被检查过。材料和方法:含有少于10个肾小球的组织被认为是不合格的。在一些病人中,病理学家在手术过程中陪同放射科医生。计算两种情况下的组织充分率和活检样本数。在病理学家采集的样本中,影响病理学家定位的因素(皮质/髓质数量,肾小球病理(整体、节段性、新月形肾小球)是否存在小管损伤、蛋白尿;检查间质炎症和间质纤维化/小管萎缩比(正常肾小球)。结果:在活检过程中提供组织充分性信息对组织充分性有积极影响。皮层的数量是病理学家的资格标准之一。在皮质充足的组织中出现蛋白尿和50%或更多的炎症会增加活检样本的数量。结论:肾活检中组织充分性的测定是重要而必要的方法。皮层的数量是组织充分性的重要参数之一。
{"title":"How does the presence of the pathologist affect the tissue adequacy and what are the factors affecting the pathologist in proficiency assessment, during percutaneous kidney biopsy?","authors":"Ş. Kaya, Ayhan Senol, Fatma Şule KUTLAR DURSUN, Serkan Çeli̇kgün","doi":"10.7197/cmj.1316057","DOIUrl":"https://doi.org/10.7197/cmj.1316057","url":null,"abstract":"Objectives: For optimal histomorphological examination, adequacy of kidney biopsy tissue \u0000should be obtained. In this study, the effect of a pathologist informing the radiologist about \u0000tissue adequacy during the biopsy procedure on obtaining tissue adequacy was examined. \u0000Furthermore, we aimed to determine the criteria that the pathologist considered in determining \u0000tissue adequacy and the conditions affecting the decision to increase the number of core \u0000biopsies, as these have not been previously examined in the literature. \u0000Materials and Methods: Tissues containing less than 10 glomeruli were considered \u0000inadequate. In some patients, a pathologist accompanied the radiologist during the procedure. \u0000Tissue adequacy ratios and biopsy sample numbers were calculated between the two \u0000conditions. In the samples taken with the pathologist, the factors affecting the locality \u0000decision of the pathologist (cortex/medulla amount, presence of glomerular pathology(global, \u0000segmental, crescentic glomeruli) presence of tubular injury, proteinuria; interstitial \u0000inflammation and interstitial fibrosis/tubular atrophy ratios, account of normal glomeruli) \u0000were examined. \u0000Results: Giving tissue adequacy information during the biopsy procedure had a positive \u0000effect on tissue adequacy. The amount of cortex is one of the qualification criteria for the \u0000pathologist. The presence of proteinuria and 50% or more inflammation in tissues with \u0000sufficient cortex increased the number of biopsy samples. \u0000 \u0000Conclusion: Determination of tissue adequacy during kidney biopsy is an important and \u0000necessary method. The amount of cortex is one of the important parameters in tissue \u0000adequacy.","PeriodicalId":10750,"journal":{"name":"Cumhuriyet medical journal","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78504256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Cumhuriyet medical journal
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