Compound that is a novel tetradentate Schiff base ligand [(3,4-bis(((E)-4-(diethylamino)-2-hydroxybenzylidene)amino)phenyl)(phenyl) methanone] (1), 4-(diethylamino) It was synthesized by the reaction of (3,4-diaminophenyl)(phenyl)methanone with -2-hydroxybenzaldehyde. Complex reactions with Co(II) (1a), Cu(II) (1b) and Ni(II) (1c) metals were prepared based on the obtained Schiff base ligand. The synthesized Schiff base and its Ni(II), Cu(II) and Co(II) complexes were featured using FT-IR, UV-vis, photoluminescence, mass and 1H and 13C-NMR spectroscopy. The characterization processes show that the tetradentate Schiff base compound coordinates with metal ions, oxygen of the hydroxyl group and nitrogen of the azomethine group.
{"title":"Synthesis and Characterization of Tetradentate Schiff Base Ligand Containing 3,4-Diamino Benzophenone and Investigation of Complex Formation with Ni (II), Cu (II) and Co (II) metal ions","authors":"M. Bal","doi":"10.17776/csj.1210668","DOIUrl":"https://doi.org/10.17776/csj.1210668","url":null,"abstract":"Compound that is a novel tetradentate Schiff base ligand [(3,4-bis(((E)-4-(diethylamino)-2-hydroxybenzylidene)amino)phenyl)(phenyl) methanone] (1), 4-(diethylamino) It was synthesized by the reaction of (3,4-diaminophenyl)(phenyl)methanone with -2-hydroxybenzaldehyde. Complex reactions with Co(II) (1a), Cu(II) (1b) and Ni(II) (1c) metals were prepared based on the obtained Schiff base ligand. The synthesized Schiff base and its Ni(II), Cu(II) and Co(II) complexes were featured using FT-IR, UV-vis, photoluminescence, mass and 1H and 13C-NMR spectroscopy. The characterization processes show that the tetradentate Schiff base compound coordinates with metal ions, oxygen of the hydroxyl group and nitrogen of the azomethine group.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49219415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this study, Copper Indium Gallium Selenide (CIGS) thin films were successfully sputtered from a single quaternary target onto soda lime glass substrates. The effect of the incident angle of target atoms and sputter temperature on the properties of the films were examined using various techniques. It was found that a higher incident angle of target atoms resulted in a columnar microstructure, while a lower angle produced a solid film. The columnar structure showed improved optical absorption compared to the solid film. The sputter temperature had a greater effect on the crystalline properties of the films, with all films except those sputtered at room temperature showing polycrystalline formation. The films displayed a chalcopyrite structure and acceptable band gaps in the range of 1.1-1.3 eV, regardless of the incident angle and sputter temperature. These results indicate that the optical properties of CIGS thin films can be improved by a small increase in the incident angle of target atoms, without adversely affecting the structural and crystalline properties.
{"title":"Influence of The Substrate-Target Angle and Sputter Temperature On The Properties of CIGS Thin Films Sputtered From Single Quaternary Target","authors":"F. Keleş, Furkan Güçlüer","doi":"10.17776/csj.1242731","DOIUrl":"https://doi.org/10.17776/csj.1242731","url":null,"abstract":"In this study, Copper Indium Gallium Selenide (CIGS) thin films were successfully sputtered from a single quaternary target onto soda lime glass substrates. The effect of the incident angle of target atoms and sputter temperature on the properties of the films were examined using various techniques. It was found that a higher incident angle of target atoms resulted in a columnar microstructure, while a lower angle produced a solid film. The columnar structure showed improved optical absorption compared to the solid film. The sputter temperature had a greater effect on the crystalline properties of the films, with all films except those sputtered at room temperature showing polycrystalline formation. The films displayed a chalcopyrite structure and acceptable band gaps in the range of 1.1-1.3 eV, regardless of the incident angle and sputter temperature. These results indicate that the optical properties of CIGS thin films can be improved by a small increase in the incident angle of target atoms, without adversely affecting the structural and crystalline properties.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48374607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this paper, we consider the inverse nodal problem for the conformable fractional diffusion operator with parameter-dependent Bitsadze–Samarskii type nonlocal boundary condition. We obtain the asymptotics for the eigenvalues, the eigenfunctions, and the zeros of the eigenfunctions (called nodal points or nodes) of the considered operator, and provide a constructive procedure for solving the inverse nodal problem, i.e., we reconstruct the potential functions p(x) and q(x) by using a dense subset of the nodal points.
{"title":"Inverse Nodal Problem for a Conformable Fractional Diffusion Operator With Parameter-Dependent Nonlocal Boundary Condition","authors":"Yaşar ÇAKMAK","doi":"10.17776/csj.1243136","DOIUrl":"https://doi.org/10.17776/csj.1243136","url":null,"abstract":"In this paper, we consider the inverse nodal problem for the conformable fractional diffusion operator with parameter-dependent Bitsadze–Samarskii type nonlocal boundary condition. We obtain the asymptotics for the eigenvalues, the eigenfunctions, and the zeros of the eigenfunctions (called nodal points or nodes) of the considered operator, and provide a constructive procedure for solving the inverse nodal problem, i.e., we reconstruct the potential functions p(x) and q(x) by using a dense subset of the nodal points.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135857669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this study, we analyze a cancer model which includes the interactions among tumor cells, healthy host cells and effector immune cells. The model with continuous case has been studied in the literature and it has been shown that it exhibits chaotic behavior. In this paper, we aim to build a better understanding of how both discrete and continuous times affect the dynamic behavior of the tumor growth model. So, we reconsider the model as a system of differential equations with piecewise constant argument. To analyze dynamical behavior of the model, we consider the solution of the system in a certain subinterval which leads to the system of difference equations. Some theoretical results are obtained for local behavior of the system. In addition, we study chaotic dynamic of the system through Neimark-Sacker bifurcation by using Lyapunov exponents
{"title":"Chaos in a Three-Dimensional Cancer Model with Piecewise Constant Arguments","authors":"S. Kartal","doi":"10.17776/csj.1239101","DOIUrl":"https://doi.org/10.17776/csj.1239101","url":null,"abstract":"In this study, we analyze a cancer model which includes the interactions among tumor cells, healthy host cells and effector immune cells. The model with continuous case has been studied in the literature and it has been shown that it exhibits chaotic behavior. In this paper, we aim to build a better understanding of how both discrete and continuous times affect the dynamic behavior of the tumor growth model. So, we reconsider the model as a system of differential equations with piecewise constant argument. To analyze dynamical behavior of the model, we consider the solution of the system in a certain subinterval which leads to the system of difference equations. Some theoretical results are obtained for local behavior of the system. In addition, we study chaotic dynamic of the system through Neimark-Sacker bifurcation by using Lyapunov exponents","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42486953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. I. Olatona, Oluwapelumi Aji̇lore, Fakunle MUTİU ALANİ, Paul Olani̇yi̇, Makinde Tosi̇n
The estimation of solar radiation intensity has been a focus of many researchers due to the cost of setting up its actual measurements. While many of them employed empirical models, this study utilizes the artificial neural network for the analysis and estimation of global solar radiation over two Nigerian cities. The model developed using sunshine hours, temperatures and relative humidity were compared with the existing empirical models. Model performance indicators comparing the measured data and the computed data for the derived and selected models, using the same number of input meteorological parameters showed that ANN having average values of RMSE, MBE, and MPE of 0.0744 MJm-2day-1, -0.0020 MJm-2day-1, and -0.0043%, respectively, performed slightly better. When different number of input meteorological parameters were used, the ANN gave the following error indicators for RMSE, MBE, MPE of 0.0394MJm-2day-1, -0.0023MJm-2day-1 and -0.0144% respectively. Also, in the result of solar radiation in Abuja, using the same number of meteorological parameters, the model with the best performance in the estimation of solar radiation is the ANN model with average values of RMSE, MBE, MPE of 0.1301MJm-2day-1, 0.0053MJm-2day-1 and 0.0441% respectively. Hence, the models are versatile for predicting global solar radiation in locations in the same climatic zones as locations studied in this study, where direct measurements of solar radiation is scarce and widely separated but there is availability of commonly measured meteorological parameters such as sunshine duration, minimum temperature, maximum temperature and relative humidity.
{"title":"Comparative Estimation of Global Solar Radiation over Two Nigerian Cities, Using Artificial Neural Network and Empirical Models","authors":"G. I. Olatona, Oluwapelumi Aji̇lore, Fakunle MUTİU ALANİ, Paul Olani̇yi̇, Makinde Tosi̇n","doi":"10.17776/csj.1182017","DOIUrl":"https://doi.org/10.17776/csj.1182017","url":null,"abstract":"The estimation of solar radiation intensity has been a focus of many researchers due to the cost of setting up its actual measurements. While many of them employed empirical models, this study utilizes the artificial neural network for the analysis and estimation of global solar radiation over two Nigerian cities. The model developed using sunshine hours, temperatures and relative humidity were compared with the existing empirical models. Model performance indicators comparing the measured data and the computed data for the derived and selected models, using the same number of input meteorological parameters showed that ANN having average values of RMSE, MBE, and MPE of 0.0744 MJm-2day-1, -0.0020 MJm-2day-1, and -0.0043%, respectively, performed slightly better. When different number of input meteorological parameters were used, the ANN gave the following error indicators for RMSE, MBE, MPE of 0.0394MJm-2day-1, -0.0023MJm-2day-1 and -0.0144% respectively. Also, in the result of solar radiation in Abuja, using the same number of meteorological parameters, the model with the best performance in the estimation of solar radiation is the ANN model with average values of RMSE, MBE, MPE of 0.1301MJm-2day-1, 0.0053MJm-2day-1 and 0.0441% respectively. Hence, the models are versatile for predicting global solar radiation in locations in the same climatic zones as locations studied in this study, where direct measurements of solar radiation is scarce and widely separated but there is availability of commonly measured meteorological parameters such as sunshine duration, minimum temperature, maximum temperature and relative humidity.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48524938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of this study is to determine the relationship between the influencing factors in the data set created with the help of canonical correlation in the factors affecting the purchase or sale of agricultural lands in certain neighborhoods in the Dulkadiroğlu district of Kahramanmaraş province and the most effective factor or factors compared to the others. For this, a survey was conducted with the parcel owners in the determined neighborhoods and a data set of 1000 people was created. As a result of the data obtained, the first data set of the study, in which the canonical correlation method was used, was the slope and irrigation status of the land, the average productivity rate of the land, and the presence of tractors and equipment used in the land, among the factors affecting the purchase or sale of agricultural lands; land parcel size, land purchase or sale price and for what purpose the land was bought or sold were also the second data set. The rate of canonical correlation coefficient in the data sets created according to the estimation results was found to be 40.32%. In the data set we compared, the average productivity of the land was determined in the first data set with the highest effect, while in the second data set it was determined as the purpose for which the land was bought or sold
{"title":"Determination of Impact Size by Canonic Correlation Analysis of the Factors Affecting the Buying or Selling Agricultural Lands","authors":"İsmail Gök, M. Şahi̇n, Tolga Tolun","doi":"10.17776/csj.1139858","DOIUrl":"https://doi.org/10.17776/csj.1139858","url":null,"abstract":"The aim of this study is to determine the relationship between the influencing factors in the data set created with the help of canonical correlation in the factors affecting the purchase or sale of agricultural lands in certain neighborhoods in the Dulkadiroğlu district of Kahramanmaraş province and the most effective factor or factors compared to the others. For this, a survey was conducted with the parcel owners in the determined neighborhoods and a data set of 1000 people was created. As a result of the data obtained, the first data set of the study, in which the canonical correlation method was used, was the slope and irrigation status of the land, the average productivity rate of the land, and the presence of tractors and equipment used in the land, among the factors affecting the purchase or sale of agricultural lands; land parcel size, land purchase or sale price and for what purpose the land was bought or sold were also the second data set. The rate of canonical correlation coefficient in the data sets created according to the estimation results was found to be 40.32%. In the data set we compared, the average productivity of the land was determined in the first data set with the highest effect, while in the second data set it was determined as the purpose for which the land was bought or sold","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45452245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bacillus vallismortis BR2 and Escherichia coli Khodavandi-Alizadeh-2 lipases (E.C.3.1.1.3) were used to produce fatty acid methyl ester (FAME), a sustainable source of fuel. The lipase activity was measured using the titrimetric method after it was extracted from a solid fermented substrate in phosphate buffer. The use of Central Composite Design to optimize condition parameters was examined, while qualitative and quantitative assessments of FAME samples were performed using GC-MS with MSD in scan mode and selective ion monitoring. Lipase activity peaked at 24 h and then declined as the incubation time went on. The independent variables, such as pH, temperature, agitation, incubation time and enzyme quantity, all had an effect on biodiesel yield since they were all significant in the rate of biodiesel yield. FAME yield increased significantly after adding 1 to 2 mL of enzyme and a pH range of 4.57143 to 7.42857, but thereafter declined. The chromatograms indicated a peak of cis-10-Heptadecanoic acid methyl ester with concentrations of 39.95 mg/L and 58.95 mg/L in the FAME molecules. The viscosity (3.67 m3/s), specific gravity (0.813 g/cm3), flash point (102.70 °C), cetane number (55.52), and pour point (-24 °C) of the fuel were also measured. The synthesized biodiesel from the spent oil through the synergic enzymes were found to be a simple, effective, and sustainable fuel production process, as well as a potential means of eliminating pollution caused by haphazard waste cooking oil disposal.
{"title":"Concomitant strain of Bacillus vallismortis BR2 and Escherichia coli Khodavandi-Alizadeh-2 for Biocatalytic Synthesis of Fatty Acid Methyl Ester from Waste Oil Feedstock","authors":"M. Osho, Olayinka Mary Otolori̇n","doi":"10.17776/csj.1206615","DOIUrl":"https://doi.org/10.17776/csj.1206615","url":null,"abstract":"Bacillus vallismortis BR2 and Escherichia coli Khodavandi-Alizadeh-2 lipases (E.C.3.1.1.3) were used to produce fatty acid methyl ester (FAME), a sustainable source of fuel. The lipase activity was measured using the titrimetric method after it was extracted from a solid fermented substrate in phosphate buffer. The use of Central Composite Design to optimize condition parameters was examined, while qualitative and quantitative assessments of FAME samples were performed using GC-MS with MSD in scan mode and selective ion monitoring. Lipase activity peaked at 24 h and then declined as the incubation time went on. The independent variables, such as pH, temperature, agitation, incubation time and enzyme quantity, all had an effect on biodiesel yield since they were all significant in the rate of biodiesel yield. FAME yield increased significantly after adding 1 to 2 mL of enzyme and a pH range of 4.57143 to 7.42857, but thereafter declined. The chromatograms indicated a peak of cis-10-Heptadecanoic acid methyl ester with concentrations of 39.95 mg/L and 58.95 mg/L in the FAME molecules. The viscosity (3.67 m3/s), specific gravity (0.813 g/cm3), flash point (102.70 °C), cetane number (55.52), and pour point (-24 °C) of the fuel were also measured. The synthesized biodiesel from the spent oil through the synergic enzymes were found to be a simple, effective, and sustainable fuel production process, as well as a potential means of eliminating pollution caused by haphazard waste cooking oil disposal.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47615248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Accumulating evidence reports that T-type calcium channels play crucial roles in tumor formation and development. However, the roles of inhibiting calcium channels in tumor cells with various inhibitors in tumor progression remain unclear. This study aimed to investigate the cytotoxic and apoptotic effects of NNC 55-0396, a T-type calcium channel inhibitor, against SNU-1 gastric cancer cells. Cytotoxic and apoptotic effects of NNC 55-0396 were evaluated by the XTT assay and flow cytometry. The results showed that NNC 55-0396 had concentration-dependent cytotoxicity in SNU-1 cells and its the half-maximal inhibitory concentration (IC50) value was calculated as 4.17 µM. The results of the Annexin V experiments also showed that this inhibitor significantly increased apoptosis in SNU-1 cells. In conclusion, these results demonstrated that NNC 55-0396 induces cytotoxic effects by increasing apoptosis in gastric cancer cells. However, further research is required for its use as a possible therapeutic agent in the treatment of gastric cancer.
{"title":"T-type Calcium Channel Blocker, NNC 55-0396, Suppress Cell Proliferation and Promote Apoptosis in SNU-1 Gastric Cancer Cells","authors":"M. Ergül","doi":"10.17776/csj.1238418","DOIUrl":"https://doi.org/10.17776/csj.1238418","url":null,"abstract":"Accumulating evidence reports that T-type calcium channels play crucial roles in tumor formation and development. However, the roles of inhibiting calcium channels in tumor cells with various inhibitors in tumor progression remain unclear. This study aimed to investigate the cytotoxic and apoptotic effects of NNC 55-0396, a T-type calcium channel inhibitor, against SNU-1 gastric cancer cells. Cytotoxic and apoptotic effects of NNC 55-0396 were evaluated by the XTT assay and flow cytometry. The results showed that NNC 55-0396 had concentration-dependent cytotoxicity in SNU-1 cells and its the half-maximal inhibitory concentration (IC50) value was calculated as 4.17 µM. The results of the Annexin V experiments also showed that this inhibitor significantly increased apoptosis in SNU-1 cells. In conclusion, these results demonstrated that NNC 55-0396 induces cytotoxic effects by increasing apoptosis in gastric cancer cells. However, further research is required for its use as a possible therapeutic agent in the treatment of gastric cancer.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49181916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The elasto-plastic contact problem with an unknown contact domain (UCD) has attracted mathematicians, mechanics and engineers for decades. So, the problem of determining the stresses in the UCD is very important nowadays in terms of engineering and applied mathematics. To improve the finite element model, the remeshing algorithm is used for the considered indentation problem. The algorithm allows the determination of the UCD at each step of the indentation with high accuracy. This paper presents the analysis and numerical solution of the boundary value problem for the Lame system, and the modeling of the contact problem for rigid materials. By using barycentric coordinates, the finite difference approximation of the mathematical model of the deformation problem with undetermined bounded is obtained and the relations between the finite elements and finite differences are investigated.
{"title":"OBTAINING THE FINITE DIFFERENCE APPROXIMATION OF THE LAME SYSTEM BY USING BARYCENTRIC COORDINATES","authors":"Vildan Yazici","doi":"10.17776/csj.1058866","DOIUrl":"https://doi.org/10.17776/csj.1058866","url":null,"abstract":"The elasto-plastic contact problem with an unknown contact domain (UCD) has attracted mathematicians, mechanics and engineers for decades. So, the problem of determining the stresses in the UCD is very important nowadays in terms of engineering and applied mathematics. To improve the finite element model, the remeshing algorithm is used for the considered indentation problem. The algorithm allows the determination of the UCD at each step of the indentation with high accuracy. This paper presents the analysis and numerical solution of the boundary value problem for the Lame system, and the modeling of the contact problem for rigid materials. By using barycentric coordinates, the finite difference approximation of the mathematical model of the deformation problem with undetermined bounded is obtained and the relations between the finite elements and finite differences are investigated.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48575490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paraquat and dicamba are chemicals commonly used in agriculture for plant control. The US Environmental Protection Agency (EPA) has classified paraquat into a restricted use class for use only by practitioners, as it is highly toxic. In this study, the effects of different concentrations of paraquat and dicamba toxic substances on C. elegans were studied. In tests, C. elegans were directly exposed to different concentrations of paraquat and dicamba for 6h, 12h, 18h, 24h. In particular, it was determined at which paraquat and dicamba doses that half of the C. elegans individuals (LC50) died. In the analysis results, paraquat LC50 values were found as LC50 6h= LC50 6h= 7412 µM, LC50 12h= 459 µM, LC50 18h= 123 µM, LC50 24h= 61 µM. Similarly, dicamba LC50 values were found as LC50 6h= 14610 µM, LC50 12h= 1404 µM, LC50 18h= 906 µM, LC50 24h= 463 µM.
{"title":"Toxicity of Paraquat and Dicamba on Caenorhabditis Elegans LC50 Value","authors":"A. Zöngür, Musa Sari","doi":"10.17776/csj.1150823","DOIUrl":"https://doi.org/10.17776/csj.1150823","url":null,"abstract":"Paraquat and dicamba are chemicals commonly used in agriculture for plant control. The US Environmental Protection Agency (EPA) has classified paraquat into a restricted use class for use only by practitioners, as it is highly toxic. In this study, the effects of different concentrations of paraquat and dicamba toxic substances on C. elegans were studied. In tests, C. elegans were directly exposed to different concentrations of paraquat and dicamba for 6h, 12h, 18h, 24h. In particular, it was determined at which paraquat and dicamba doses that half of the C. elegans individuals (LC50) died. In the analysis results, paraquat LC50 values were found as LC50 6h= LC50 6h= 7412 µM, LC50 12h= 459 µM, LC50 18h= 123 µM, LC50 24h= 61 µM. Similarly, dicamba LC50 values were found as LC50 6h= 14610 µM, LC50 12h= 1404 µM, LC50 18h= 906 µM, LC50 24h= 463 µM.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45264424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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