Pub Date : 2023-03-15DOI: 10.20473/j.djmkg.v56.i2.p115-121
C. Prahasanti, Niken Luthfiyya Arini, Kurnia Dwi Wulan, Onge Victoria Hendro, I. Wijaksana, N. Ulfah, B. Kusumawardani, Padmini Hari, S. Abullais
Background: Periodontitis is a chronic inflammatory disease of the periodontal tissue that is characterized by alveolar bone resorption. This occurs due to an imbalance of osteoblast and osteoclast during the bone formation and resorption processes. In order to obtain complete regeneration of periodontal tissue, bone grafting is frequently used in periodontal surgical therapy. Although each material has disadvantages, safe graft materials derived from animal sources can be employed as an alternative to bone graft materials. Osteoblast, osteoclast, calcified bone matrix, type I collagen, osteonectin, and hydroxyapatite can all be found in gourami scales, a form of food waste. BMP4 has osteoinduction functions, which are important in bone metabolism. Through angiogenic activity, FGF2 also contributes to periodontal regeneration. Purpose: The aim of the study was to assess the expression of BMP4 and FGF2 after the treatment group had been given gourami fish scale extract. Methods: Thirty-two experimental three-month-old male Wistar rats (150-200g) were randomly divided into four groups: a seven-day control group, a seven-day treatment group, a 14-day control group, and a 14-day treatment group. One mandibular incisor was extracted from each Wistar rat. The post-extraction socket was filled with blood for the control group and collagen extract for the treatment. Results: The one-way ANOVA test showed a significance level of 0.000 (p = <0.05). Conclusion: The expression of BMP4 and FGF2 increased after the application of collagen extract from gourami scales.
{"title":"The expression of BMP4 and FGF2 in Wistar rats (Rattus norvegicus) post application of gourami fish (Osphronemus goramy) collagen","authors":"C. Prahasanti, Niken Luthfiyya Arini, Kurnia Dwi Wulan, Onge Victoria Hendro, I. Wijaksana, N. Ulfah, B. Kusumawardani, Padmini Hari, S. Abullais","doi":"10.20473/j.djmkg.v56.i2.p115-121","DOIUrl":"https://doi.org/10.20473/j.djmkg.v56.i2.p115-121","url":null,"abstract":"Background: Periodontitis is a chronic inflammatory disease of the periodontal tissue that is characterized by alveolar bone resorption. This occurs due to an imbalance of osteoblast and osteoclast during the bone formation and resorption processes. In order to obtain complete regeneration of periodontal tissue, bone grafting is frequently used in periodontal surgical therapy. Although each material has disadvantages, safe graft materials derived from animal sources can be employed as an alternative to bone graft materials. Osteoblast, osteoclast, calcified bone matrix, type I collagen, osteonectin, and hydroxyapatite can all be found in gourami scales, a form of food waste. BMP4 has osteoinduction functions, which are important in bone metabolism. Through angiogenic activity, FGF2 also contributes to periodontal regeneration. Purpose: The aim of the study was to assess the expression of BMP4 and FGF2 after the treatment group had been given gourami fish scale extract. Methods: Thirty-two experimental three-month-old male Wistar rats (150-200g) were randomly divided into four groups: a seven-day control group, a seven-day treatment group, a 14-day control group, and a 14-day treatment group. One mandibular incisor was extracted from each Wistar rat. The post-extraction socket was filled with blood for the control group and collagen extract for the treatment. Results: The one-way ANOVA test showed a significance level of 0.000 (p = <0.05). Conclusion: The expression of BMP4 and FGF2 increased after the application of collagen extract from gourami scales.","PeriodicalId":11034,"journal":{"name":"Dental Journal (Majalah Kedokteran Gigi)","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88106946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-15DOI: 10.20473/j.djmkg.v56.i2.p73-79
I. J. Savitri, I. Wijaksana, Okkinardo Arief, Muhammad Nur Falah, U. Tedjosasongko, Olivia Bambang Siswanto, K. Ouhara, H. Kurihara, N. Mizuno
Background: The treatment of severe periodontitis must consider immune responses and local conditions, including the aesthetical aspects. The tooth loss in the anterior area can lead to a psychological issue in some patients, and the daily use of dexamethasone contributes greatly to the severity of aesthetical aspects. Periodontal treatments must be cautious of these aesthetical effects. Purpose: To report the aesthetical consideration in patient management of severe periodontitis aggravated by oral dexamethasone. Case: The 44-year-old female patient reported having tooth mobility in the upper right and left central incisor and lower right and left posterior. Due to the condition, the central anterior needed to be extracted. The patient had seafood allergies and consumed oral dexamethasone periodically to prevent allergic reactions for two years. Case management: The initial periodontal therapy was designed prior to the tooth extraction, socket preservation, and immediate denture on teeth 11 and 21. A metal frame combined with an acrylic denture was designed to support the tooth splint and replace the teeth on the mandible. The patient was treated with 20 mg of sub-antimicrobial-dose doxycycline twice a day for three months, and vitamin E was prescribed once a day. Since dexamethasone may contribute to immune response and osteoclastogenesis, dexamethasone was replaced by cetirizine. Conclusion: The treatment of severe chronic periodontitis must consider immune responses, local conditions, and aesthetical aspects. In this case, the use of dexamethasone might worsen the periodontal breakdown. However, the periodontal treatment, use of host modulation therapy, and replacement of dexamethasone with cetirizine are expected to improve these conditions.
{"title":"Aesthetic consideration in patient management of severe periodontitis aggravated by oral dexamethasone","authors":"I. J. Savitri, I. Wijaksana, Okkinardo Arief, Muhammad Nur Falah, U. Tedjosasongko, Olivia Bambang Siswanto, K. Ouhara, H. Kurihara, N. Mizuno","doi":"10.20473/j.djmkg.v56.i2.p73-79","DOIUrl":"https://doi.org/10.20473/j.djmkg.v56.i2.p73-79","url":null,"abstract":"Background: The treatment of severe periodontitis must consider immune responses and local conditions, including the aesthetical aspects. The tooth loss in the anterior area can lead to a psychological issue in some patients, and the daily use of dexamethasone contributes greatly to the severity of aesthetical aspects. Periodontal treatments must be cautious of these aesthetical effects. Purpose: To report the aesthetical consideration in patient management of severe periodontitis aggravated by oral dexamethasone. Case: The 44-year-old female patient reported having tooth mobility in the upper right and left central incisor and lower right and left posterior. Due to the condition, the central anterior needed to be extracted. The patient had seafood allergies and consumed oral dexamethasone periodically to prevent allergic reactions for two years. Case management: The initial periodontal therapy was designed prior to the tooth extraction, socket preservation, and immediate denture on teeth 11 and 21. A metal frame combined with an acrylic denture was designed to support the tooth splint and replace the teeth on the mandible. The patient was treated with 20 mg of sub-antimicrobial-dose doxycycline twice a day for three months, and vitamin E was prescribed once a day. Since dexamethasone may contribute to immune response and osteoclastogenesis, dexamethasone was replaced by cetirizine. Conclusion: The treatment of severe chronic periodontitis must consider immune responses, local conditions, and aesthetical aspects. In this case, the use of dexamethasone might worsen the periodontal breakdown. However, the periodontal treatment, use of host modulation therapy, and replacement of dexamethasone with cetirizine are expected to improve these conditions.","PeriodicalId":11034,"journal":{"name":"Dental Journal (Majalah Kedokteran Gigi)","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80722136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-15DOI: 10.20473/j.djmkg.v56.i2.p109-114
P. Pujiastuti, N. Sakinah, Y. M. D. Arina, M. A. Wahyukundari, Depi Praharani, D. Sari
Background: The prevention of gingivitis using chemicals containing antibiotics and chlorhexidine can disrupt the balance of the oral microbiota and have side effects in long-term use. A recent development in the prevention of gingivitis is the use of natural ingredients. Coffee is a natural ingredient that compounds several antibacterial and anti-inflammation properties. Purpose: The study aimed to determine the potential of toothpaste containing Robusta coffee bean extract in reducing gingival inflammation and inhibiting the formation of dental plaque. Methods: Twenty male Rattus norvegicus were divided into four groups, namely the control group and treatment groups (TG) TG25%, TG50%, and TG75%. All groups were fitted with ligature wire on the first left molar to accumulate dental plaque. After the fourth day, the ligature wire was removed, and the TG25%, TG50%, and TG75% groups were brushed once a day using toothpaste containing various concentrations of Robusta coffee extract, while the control group was brushed without using toothpaste. Plaque index, gingival index, and interleukin-1 (IL-1) expression were observed on the fifth day. The data was statistically tested using a one-way analysis of variance and post hoc least significant difference. Results: The statistical test showed that the TG75% group had the lowest value of plaque, gingival index, and IL-1 expression, while the control group had the highest (p < 0.05). Conclusion: Robusta coffee bean extract toothpaste has the potential to reduce gingival inflammation and dental plaque formation in a rat with gingivitis. The most effective concentration of Robusta coffee bean extract toothpaste in reducing gingival inflammation and dental plaque formation was 75%.
{"title":"The potential of toothpaste containing Robusta coffee bean extract in reducing gingival inflammation and dental plaque formation","authors":"P. Pujiastuti, N. Sakinah, Y. M. D. Arina, M. A. Wahyukundari, Depi Praharani, D. Sari","doi":"10.20473/j.djmkg.v56.i2.p109-114","DOIUrl":"https://doi.org/10.20473/j.djmkg.v56.i2.p109-114","url":null,"abstract":"Background: The prevention of gingivitis using chemicals containing antibiotics and chlorhexidine can disrupt the balance of the oral microbiota and have side effects in long-term use. A recent development in the prevention of gingivitis is the use of natural ingredients. Coffee is a natural ingredient that compounds several antibacterial and anti-inflammation properties. Purpose: The study aimed to determine the potential of toothpaste containing Robusta coffee bean extract in reducing gingival inflammation and inhibiting the formation of dental plaque. Methods: Twenty male Rattus norvegicus were divided into four groups, namely the control group and treatment groups (TG) TG25%, TG50%, and TG75%. All groups were fitted with ligature wire on the first left molar to accumulate dental plaque. After the fourth day, the ligature wire was removed, and the TG25%, TG50%, and TG75% groups were brushed once a day using toothpaste containing various concentrations of Robusta coffee extract, while the control group was brushed without using toothpaste. Plaque index, gingival index, and interleukin-1 (IL-1) expression were observed on the fifth day. The data was statistically tested using a one-way analysis of variance and post hoc least significant difference. Results: The statistical test showed that the TG75% group had the lowest value of plaque, gingival index, and IL-1 expression, while the control group had the highest (p < 0.05). Conclusion: Robusta coffee bean extract toothpaste has the potential to reduce gingival inflammation and dental plaque formation in a rat with gingivitis. The most effective concentration of Robusta coffee bean extract toothpaste in reducing gingival inflammation and dental plaque formation was 75%.","PeriodicalId":11034,"journal":{"name":"Dental Journal (Majalah Kedokteran Gigi)","volume":"121 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81671404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-15DOI: 10.20473/j.djmkg.v56.i2.p127-131
U. Kresnoadi, N. Salsabila, Primanda Nur Rahmania, Phara Aster Chandra Adventia, Bima Subiakto Rahmani, N. Yoda
Background: After tooth extraction, alveolar bone resorption occurs naturally, followed by alveolar bone remodeling. Alveolar bone formation is characterized by an increase in density and expansion of the trabecular bone. Socket preservation using a combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) is expected to increase the area of the alveolar bone trabeculae and thus accelerate the process of alveolar bone formation. Purpose: This study aimed to determine if a combination of Moringa oleifera leaf extract and DFDBBX could increase the area of the alveolar bone trabeculae in tooth extraction sockets. Methods: With their lower left incisors extracted, the 56 Cavia cobayas were divided into eight treatment groups according to the material given: polyethylene glycol (PEG), DFDBBX and PEG, Moringa oleifera leaf extract and PEG, and a combination of Moringa oleifera leaf extract, DFDBBX, and PEG. On the seventh and thirtieth days, the Cavia cobayas were sacrificed and examined. Histopathological samples were stained with Hematoxylin-Eosin (HE) to evaluate the trabecula area, and data were analyzed using one-way ANOVA and Tukey HSD. Results: On the thirtieth day, the group that received a combination of Moringa oleifera leaf extract and DFDBBX had the greatest area of alveolar bone trabeculae. Conclusion: A combination of Moringa oleifera leaf extract and DFDBBX induced in the tooth extraction socket can increase the area of the alveolar bone trabeculae.
{"title":"Post-tooth extraction induction effect of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft treatment on alveolar bone trabecula area","authors":"U. Kresnoadi, N. Salsabila, Primanda Nur Rahmania, Phara Aster Chandra Adventia, Bima Subiakto Rahmani, N. Yoda","doi":"10.20473/j.djmkg.v56.i2.p127-131","DOIUrl":"https://doi.org/10.20473/j.djmkg.v56.i2.p127-131","url":null,"abstract":"Background: After tooth extraction, alveolar bone resorption occurs naturally, followed by alveolar bone remodeling. Alveolar bone formation is characterized by an increase in density and expansion of the trabecular bone. Socket preservation using a combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) is expected to increase the area of the alveolar bone trabeculae and thus accelerate the process of alveolar bone formation. Purpose: This study aimed to determine if a combination of Moringa oleifera leaf extract and DFDBBX could increase the area of the alveolar bone trabeculae in tooth extraction sockets. Methods: With their lower left incisors extracted, the 56 Cavia cobayas were divided into eight treatment groups according to the material given: polyethylene glycol (PEG), DFDBBX and PEG, Moringa oleifera leaf extract and PEG, and a combination of Moringa oleifera leaf extract, DFDBBX, and PEG. On the seventh and thirtieth days, the Cavia cobayas were sacrificed and examined. Histopathological samples were stained with Hematoxylin-Eosin (HE) to evaluate the trabecula area, and data were analyzed using one-way ANOVA and Tukey HSD. Results: On the thirtieth day, the group that received a combination of Moringa oleifera leaf extract and DFDBBX had the greatest area of alveolar bone trabeculae. Conclusion: A combination of Moringa oleifera leaf extract and DFDBBX induced in the tooth extraction socket can increase the area of the alveolar bone trabeculae.","PeriodicalId":11034,"journal":{"name":"Dental Journal (Majalah Kedokteran Gigi)","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80187198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-15DOI: 10.20473/j.djmkg.v56.i2.p68-72
E. Onay, C. Koç, M. Ungor
Background: Pre-eruptive intracoronal resorption (PEIR) is a rare condition usually detected through an incidental radiographic finding. The etiology and pathogenesis of this phenomenon are not fully understood. Purpose: To describe two cases in which multiple impacted third molars with PEIR defects were identified. Cases: Female patients aged 77 and 82 years, respectively, were presented with dental issues. Radiolucencies in the dental crown areas of the impacted maxillary and mandibular third molars were initially detected on the panoramic radiographs. Cone-beam computed tomography (CBCT) was performed to better evaluate the impacted teeth. The results showed that the intracoronal defects extended through more than two-thirds of the thickness of the coronal dentin. Case Managements: Considering the patients’ age and their asymptomatic status, a conservative approach with radiographic follow-up was considered most appropriate. Four-year follow-up checks revealed that the teeth remained asymptomatic in both patients. Conclusion: This case report confirms that PEIR can affect impacted third molars, even in elderly patients. CBCT images are preferred for diagnosing PEIR defects because this method provides an accurate assessment of internal tooth anatomy. With an accurate diagnosis of asymptomatic PEIR, the lesion can be monitored.
{"title":"Multiple impacted third molars with pre-eruptive intracoronal resorption in geriatric patients: Two case reports","authors":"E. Onay, C. Koç, M. Ungor","doi":"10.20473/j.djmkg.v56.i2.p68-72","DOIUrl":"https://doi.org/10.20473/j.djmkg.v56.i2.p68-72","url":null,"abstract":"Background: Pre-eruptive intracoronal resorption (PEIR) is a rare condition usually detected through an incidental radiographic finding. The etiology and pathogenesis of this phenomenon are not fully understood. Purpose: To describe two cases in which multiple impacted third molars with PEIR defects were identified. Cases: Female patients aged 77 and 82 years, respectively, were presented with dental issues. Radiolucencies in the dental crown areas of the impacted maxillary and mandibular third molars were initially detected on the panoramic radiographs. Cone-beam computed tomography (CBCT) was performed to better evaluate the impacted teeth. The results showed that the intracoronal defects extended through more than two-thirds of the thickness of the coronal dentin. Case Managements: Considering the patients’ age and their asymptomatic status, a conservative approach with radiographic follow-up was considered most appropriate. Four-year follow-up checks revealed that the teeth remained asymptomatic in both patients. Conclusion: This case report confirms that PEIR can affect impacted third molars, even in elderly patients. CBCT images are preferred for diagnosing PEIR defects because this method provides an accurate assessment of internal tooth anatomy. With an accurate diagnosis of asymptomatic PEIR, the lesion can be monitored.","PeriodicalId":11034,"journal":{"name":"Dental Journal (Majalah Kedokteran Gigi)","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77433453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peningkatan jumlah penduduk usia lanjut dan semakin bervariasinya jenis makanan menjadi tantangan bagi pemeliharaan kesehatan gigi dan mulut. Aspek gizi seperti frekuensi dan jumlah asupan makanan yang memengaruhi berat badan dapat pula memengaruhi kesehatan gigi dan mulut terutama pada usia lanjut. Tujuan penelitian ini adalah untuk mengetahui hubungan indeks massa tubuh (IMT) dengan kesehatan gigi dan mulut. Studi ini merupakan studi potong lintang dengan partisipan sebanyak 186 orang berusia 60-84 tahun yang terdiri dari 87 laki-laki dan 99 perempuan dilakukan pemeriksaan kesehatan gigi dan mulut yaitu jumlah gigi dalam mulut, indeks kebersihan mulut (OHI), indeks karies (DMFT), perdarahan saat probing (BOP), kedalaman poket (PPD), dan kehilangan perlekatan (CAL). Uji korelasi Pearson dilakukan pada IMT dan enam variabel pemeriksaan gigi dan mulut. Hasil uji menunjukkan terdapat hubungan antara IMT dengan jumlah gigi (r = 0,233, p < 0,05), kebersihan mulut (r = -0,384, p < 0,05), perdarahan saat probing (r = -0,249, p < 0,05), kedalaman poket ≥ 4 mm (r = 0,177, p < 0,05), dan kehilanganperlekatan (r = -0,167, p < 0,05). Tidak terdapat hubungan antara IMT dengan status karies gigi (r = -0,137, p > 0,05).
老年人口的增加和食物种类的变化是维持牙齿和口腔健康的一个挑战。营养方面，如影响体重的食物的频率和摄入量，也会影响牙齿和口腔的健康，尤其是在老年。本研究的目的是确定身体质量指数与口腔健康的关系。这研究是研究剪60-84岁的纬度和参与者多达186人组成87和99男女做牙科和口腔健康检查嘴里的牙齿,口腔卫生分类索引的数量(芝),导致龋齿(DMFT索引)探测(BOP)的时候,口袋深度出血(PPD),失去perlekatan (CAL)。皮尔森相关测试是在IMT和六个可变的牙科和口腔检查中进行的。测试结果表明，IMT与牙齿数量(r = 233, p <)之间存在联系口腔卫生(r = - 0384, p <)在检测过程中出血(r = - 249, p <)0。05),深度口袋≥4毫米(r = 0.177, p <(r = - 0167, p <)0。05)。IMT与龋齿状态(r = - 0.137, p >)之间没有联系0。05)。
{"title":"Hubungan indeks massa tubuh dengan kesehatan gigi dan mulut: studi pada usia lanjut di Daerah Istimewa Yogyakarta","authors":"Fitrina Rachmadanty Siregar, Lisdrianto Hanindriyo, Elastria Widita, Rini Widyaningrum, Bambang Priyono, Dewi Agustina","doi":"10.22146/mkgk.77112","DOIUrl":"https://doi.org/10.22146/mkgk.77112","url":null,"abstract":"Peningkatan jumlah penduduk usia lanjut dan semakin bervariasinya jenis makanan menjadi tantangan bagi pemeliharaan kesehatan gigi dan mulut. Aspek gizi seperti frekuensi dan jumlah asupan makanan yang memengaruhi berat badan dapat pula memengaruhi kesehatan gigi dan mulut terutama pada usia lanjut. Tujuan penelitian ini adalah untuk mengetahui hubungan indeks massa tubuh (IMT) dengan kesehatan gigi dan mulut. Studi ini merupakan studi potong lintang dengan partisipan sebanyak 186 orang berusia 60-84 tahun yang terdiri dari 87 laki-laki dan 99 perempuan dilakukan pemeriksaan kesehatan gigi dan mulut yaitu jumlah gigi dalam mulut, indeks kebersihan mulut (OHI), indeks karies (DMFT), perdarahan saat probing (BOP), kedalaman poket (PPD), dan kehilangan perlekatan (CAL). Uji korelasi Pearson dilakukan pada IMT dan enam variabel pemeriksaan gigi dan mulut. Hasil uji menunjukkan terdapat hubungan antara IMT dengan jumlah gigi (r = 0,233, p < 0,05), kebersihan mulut (r = -0,384, p < 0,05), perdarahan saat probing (r = -0,249, p < 0,05), kedalaman poket ≥ 4 mm (r = 0,177, p < 0,05), dan kehilanganperlekatan (r = -0,167, p < 0,05). Tidak terdapat hubungan antara IMT dengan status karies gigi (r = -0,137, p > 0,05).","PeriodicalId":11034,"journal":{"name":"Dental Journal (Majalah Kedokteran Gigi)","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136176500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tindakan operasi pada daerah maksilofasial dapat mengakibatkan cacat wajah, gangguan fungsi bicara, penelanan, pengunyahan, estetik serta gangguan kejiwaan. Hilangnya kontinuitas mandibula dapat mengganggu keseimbangan fungsi mandibula, menyebabkan gerakan mandibula yang berubah-ubah, sehingga terjadi kecacatan, sulit menelan, gangguan bicara dan artikulasi, serta deviasi dari sisa fragmen menuju sisi yang dioperasi. Saat membuka mulut, deviasi ini meningkat dan mengarah ke pembukaan dan penutupan secara angular. Perangkat korektif bernama guide flange prosthesis ditunjukkan untuk mengatasi manifestasi klinis tersebut. Tujuan laporan kasus ini adalah untuk mengkaji penggunaan mandibular guide flange prosthesis pada pasien pasca hemimandibulektomi dekstra, sebagai rehabilitasi fungsi pengunyahan, penelanan, fonetik dan estetika. Kesimpulan dari laporan kasus ini adalah protesa mandibula dengan guide flange dari bahan resin akrilik dapat merehabilitasi defek pada mandibula pasca hemimandibulektomi sehingga mengembalikan fungsi pengunyahan, fonetik, proses penelanan dan estetika.
{"title":"Definitive mandibular guide flange prosthesis pada pasien pasca hemimandibulektomi dekstra","authors":"Sigit Ariawan, Endang Wahyuningtyas, Suparyono Saleh, Murti Indrastuti","doi":"10.22146/mkgk.37280","DOIUrl":"https://doi.org/10.22146/mkgk.37280","url":null,"abstract":"Tindakan operasi pada daerah maksilofasial dapat mengakibatkan cacat wajah, gangguan fungsi bicara, penelanan, pengunyahan, estetik serta gangguan kejiwaan. Hilangnya kontinuitas mandibula dapat mengganggu keseimbangan fungsi mandibula, menyebabkan gerakan mandibula yang berubah-ubah, sehingga terjadi kecacatan, sulit menelan, gangguan bicara dan artikulasi, serta deviasi dari sisa fragmen menuju sisi yang dioperasi. Saat membuka mulut, deviasi ini meningkat dan mengarah ke pembukaan dan penutupan secara angular. Perangkat korektif bernama guide flange prosthesis ditunjukkan untuk mengatasi manifestasi klinis tersebut. Tujuan laporan kasus ini adalah untuk mengkaji penggunaan mandibular guide flange prosthesis pada pasien pasca hemimandibulektomi dekstra, sebagai rehabilitasi fungsi pengunyahan, penelanan, fonetik dan estetika. Kesimpulan dari laporan kasus ini adalah protesa mandibula dengan guide flange dari bahan resin akrilik dapat merehabilitasi defek pada mandibula pasca hemimandibulektomi sehingga mengembalikan fungsi pengunyahan, fonetik, proses penelanan dan estetika.","PeriodicalId":11034,"journal":{"name":"Dental Journal (Majalah Kedokteran Gigi)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135405562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-04DOI: 10.20473/j.djmkg.v56.i1.p30-35
Eva Febrina, Angela Evelyna, Andrie Harmaji, B. Sunendar
Background: Polymethylmethacrylate (PMMA) is one of the synthetic polymers generally used for temporary jacket crown restorations because of its good translucency, making its aesthetic value higher, but its mechanical properties, such as hardness and flexural strength are lower than composite resins. Hence, adding zirconia and cellulose filler is necessary to enhance its mechanical properties. Purpose: This is an experimental laboratory study to make nanocomposites with PMMA as a matrix with crystalline nanocellulose, zirconia, and alumina added as fillers. Methods: The crystalline nanocellulose filler was synthesized by acid hydrolysis. Zirconia and alumina were synthesized using the sol-gel technique and then characterized by transmission electron microscope and X-ray diffraction. The Micro Vickers hardness test and three-point bending tested mechanical properties. The analysis was carried out with a one-way analysis of variance, followed by a post hoc Tuckey’s test with a P < 0.05 taken as statistically significant. Results: The Micro Vickers hardness test showed the highest hardness in the group with a ratio of PMMA and zirconia-alumina filler of 50%: 2%: 48% (12.73 VHN). The results of the three-point bending test showed that the highest flexural strength was found in the control group (19.4 MPa). Conclusion: The addition of crystalline nanocellulose, zirconia, and alumina increase the hardness of the nanocomposite, while the flexural strength was lower than PMMA without filler addition.
{"title":"Properties of nanocellulose and zirconia alumina on polymethylmethacrylate dental composite","authors":"Eva Febrina, Angela Evelyna, Andrie Harmaji, B. Sunendar","doi":"10.20473/j.djmkg.v56.i1.p30-35","DOIUrl":"https://doi.org/10.20473/j.djmkg.v56.i1.p30-35","url":null,"abstract":"Background: Polymethylmethacrylate (PMMA) is one of the synthetic polymers generally used for temporary jacket crown restorations because of its good translucency, making its aesthetic value higher, but its mechanical properties, such as hardness and flexural strength are lower than composite resins. Hence, adding zirconia and cellulose filler is necessary to enhance its mechanical properties. Purpose: This is an experimental laboratory study to make nanocomposites with PMMA as a matrix with crystalline nanocellulose, zirconia, and alumina added as fillers. Methods: The crystalline nanocellulose filler was synthesized by acid hydrolysis. Zirconia and alumina were synthesized using the sol-gel technique and then characterized by transmission electron microscope and X-ray diffraction. The Micro Vickers hardness test and three-point bending tested mechanical properties. The analysis was carried out with a one-way analysis of variance, followed by a post hoc Tuckey’s test with a P < 0.05 taken as statistically significant. Results: The Micro Vickers hardness test showed the highest hardness in the group with a ratio of PMMA and zirconia-alumina filler of 50%: 2%: 48% (12.73 VHN). The results of the three-point bending test showed that the highest flexural strength was found in the control group (19.4 MPa). Conclusion: The addition of crystalline nanocellulose, zirconia, and alumina increase the hardness of the nanocomposite, while the flexural strength was lower than PMMA without filler addition.","PeriodicalId":11034,"journal":{"name":"Dental Journal (Majalah Kedokteran Gigi)","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88893811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-02DOI: 10.20473/j.djmkg.v56.i1.p23-29
V. D. Kharisma, Santika Lusia Utami, Wahyu Choirur Rizky, Tim Godefridus Antonius Dings, M. Ullah, V. Jakhmola, A. Nugraha
Background: Mumps virus (MuV) can trigger severe infections, such as parotitis, epididymo-orchitis, and meningitis. The effectiveness of MuV vaccine administration has been proven, but current outbreaks warrant the development of antivirals against MuV. Zingiber officinale var. Roscoe or ginger is often used as an alternative remedy. Currently, there are no known in vitro or in vivo studies that investigate ginger as an MuV antiviral. Purpose: This study aims to evaluate the antiviral potency of the bioactive compounds in Zingiber officinale var. Roscoe against MuV. Methods: Antiviral activity screening was conducted by druglikeness analysis, antiviral probability, molecular docking, and molecular dynamic simulation. Results: As an antiviral, 6-shogaol from Zingiber officinale var. Roscoe has potency against MuV. It has a good binding affinity and can establish interactions with the binding domain of the target protein by forming hydrogen, Van der Waals, and alkyl bonds. Conclusion: The complex of 6-shogaol_NP was predicted to be volatile but stable for triggering inhibitory activity. However, these results must be proved by in vivo and in vitro approaches to strengthen the scientific evidence.
{"title":"Molecular docking study of Zingiber officinale Roscoe compounds as a mumps virus nucleoprotein inhibitor","authors":"V. D. Kharisma, Santika Lusia Utami, Wahyu Choirur Rizky, Tim Godefridus Antonius Dings, M. Ullah, V. Jakhmola, A. Nugraha","doi":"10.20473/j.djmkg.v56.i1.p23-29","DOIUrl":"https://doi.org/10.20473/j.djmkg.v56.i1.p23-29","url":null,"abstract":"Background: Mumps virus (MuV) can trigger severe infections, such as parotitis, epididymo-orchitis, and meningitis. The effectiveness of MuV vaccine administration has been proven, but current outbreaks warrant the development of antivirals against MuV. Zingiber officinale var. Roscoe or ginger is often used as an alternative remedy. Currently, there are no known in vitro or in vivo studies that investigate ginger as an MuV antiviral. Purpose: This study aims to evaluate the antiviral potency of the bioactive compounds in Zingiber officinale var. Roscoe against MuV. Methods: Antiviral activity screening was conducted by druglikeness analysis, antiviral probability, molecular docking, and molecular dynamic simulation. Results: As an antiviral, 6-shogaol from Zingiber officinale var. Roscoe has potency against MuV. It has a good binding affinity and can establish interactions with the binding domain of the target protein by forming hydrogen, Van der Waals, and alkyl bonds. Conclusion: The complex of 6-shogaol_NP was predicted to be volatile but stable for triggering inhibitory activity. However, these results must be proved by in vivo and in vitro approaches to strengthen the scientific evidence.","PeriodicalId":11034,"journal":{"name":"Dental Journal (Majalah Kedokteran Gigi)","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84213593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-02DOI: 10.20473/j.djmkg.v56.i1.p1-6
Agung Sosiawan, Vera Rimbawani Sushanty, D. Wahjuningrum, Fery Setiawan
Background: Informed consent is an agreement between the doctor/the provider of medical services and the patient/the recipient of medical services. This relationship between these parties has changed from a paternalistic to a contractual relationship due to technological shifts. Doctors are obliged to notify the patient of all the risks and benefits of a procedure while respecting their autonomy by not intervening the decision-making process. This article will look at three government and academic hospitals in Surabaya, as informed consent has to be practiced in all medical settings. Purpose: This study aims to review the role of informed consent according to Law Number 29, 2004. Review: This study aims to discuss the characteristics of informed consent under Law Number 29, 2004, because there are too few articles addressing this issue. It also explains the roles of the patient and the doctor/dentist in informed consent according to this piece of legislation. Conclusion: According to Article 184, informed consent provides vital evidence that can be used to hold doctors and dentists legally accountable because it contains information about standard operating procedures (SOPs) that medical professionals are legally required to follow. Guidelines for informed consent are given in Law Number 29, 2004, Article 45, paragraph 2.
{"title":"A case study of informed consent in Indonesian Law Number 29, 2004","authors":"Agung Sosiawan, Vera Rimbawani Sushanty, D. Wahjuningrum, Fery Setiawan","doi":"10.20473/j.djmkg.v56.i1.p1-6","DOIUrl":"https://doi.org/10.20473/j.djmkg.v56.i1.p1-6","url":null,"abstract":"Background: Informed consent is an agreement between the doctor/the provider of medical services and the patient/the recipient of medical services. This relationship between these parties has changed from a paternalistic to a contractual relationship due to technological shifts. Doctors are obliged to notify the patient of all the risks and benefits of a procedure while respecting their autonomy by not intervening the decision-making process. This article will look at three government and academic hospitals in Surabaya, as informed consent has to be practiced in all medical settings. Purpose: This study aims to review the role of informed consent according to Law Number 29, 2004. Review: This study aims to discuss the characteristics of informed consent under Law Number 29, 2004, because there are too few articles addressing this issue. It also explains the roles of the patient and the doctor/dentist in informed consent according to this piece of legislation. Conclusion: According to Article 184, informed consent provides vital evidence that can be used to hold doctors and dentists legally accountable because it contains information about standard operating procedures (SOPs) that medical professionals are legally required to follow. Guidelines for informed consent are given in Law Number 29, 2004, Article 45, paragraph 2.","PeriodicalId":11034,"journal":{"name":"Dental Journal (Majalah Kedokteran Gigi)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87277565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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