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Study of the skin-resorptive effect of a skin antiseptic based on polyvinylpyrollidone-iodineОценка эффективности профилактических дезинфекционных мероприятий на основе комплексного анализа микробиома мест содержания служебных собак
Pub Date : 2021-12-01 DOI: 10.35411/2076-457x-2021-4-7-11
Marina Vasilevna Bidevkina, Tatyana Nikolaevna Potapova
The skin-resorptive effect of a skin antiseptic based on polyvinylpyrollidone-iodine on immature rats of different ages was studied.The skin-resorptive effect of the drug in doses of 5.0 and 0.5 g/kg was revealed on 2–6 week-old rats. The animals showed changes in thyroxine and thyroid-stimulating hormone, as well as general toxic indicators. Absorption of the drug through the skin at a dose of 0.5 g/kg on 4–8 week old rat pups has not been established. The rationale for the use of a skin antiseptic for the hygienic treatment of hands containing PVP-iodine in the age group of children from 8 years old is given. Keywords: toxicity, skin-resorptive effect, immature white rats, skin antiseptic, iodine, thyroxine, thyroid-stimulating hormone.
研究了一种以聚乙烯鹿蹄草酮碘为基础的皮肤防腐剂对不同年龄的未成熟大鼠的皮肤吸收作用。本品5.0和0.5 g/kg剂量对2 ~ 6周龄大鼠有皮肤吸收作用。这些动物显示出甲状腺素和促甲状腺激素的变化,以及一般毒性指标。在4-8周龄大鼠幼崽中,0.5 g/kg剂量的药物通过皮肤的吸收尚未确定。给出了使用皮肤杀菌剂对8岁以上儿童含pvp -碘的手进行卫生处理的理由。关键词:毒性,皮肤吸收作用,未成熟大鼠,皮肤防腐剂,碘,甲状腺素,促甲状腺激素。
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引用次数: 0
Assessment of effectiveness of organizational measures for prevention of COVID-19 among employees of large industrial enterprises 大型工业企业员工COVID-19组织预防措施有效性评估
Pub Date : 2021-12-01 DOI: 10.35411/2076-457x-2021-4-12-19
Inna Yurevna Tarmaeva, O. G. Bogdanova, V. Pankov, O. A. Molchanova, Valentina Efimovna Balzhanova, N. I. Khamnaeva
According to the regional information fund of social and hygienic monitoring, 1518 cases of 01.07.2021 diseases were registered among those working at industrial enterprises of the Republic of Buryatia as of COVID-19, of which the share of the joint-stock company Ulan-Ude Aviation Plant (hereinafter – U-UAP, aviation plant) accounts for 30.8 % or 467 cases, in the public joint-stock company Territorial Generating Company No. 14 (hereinafter – TGC-14, heat power plant) – 15.7 % or 239 cases. The incidence rate of COVID-19 in U-UAP amounted to 871.76 per 10 thousand workers, in TGC-14 – 2280.53 per 10 thousand workers. The evaluation of the effectiveness of COVID-19 prevention showed that the complex of sanitary and anti-epidemic (preventive) measures taken in the pandemic among those working at the aviation plant ensured the control of the spread of the incidence of coronavirus infection by 2.6 times, compared with the heat power plant. Keywords: disinfectants, new coronavirus infection of COVID-19, industrial enterprises, sanitary and anti-epidemic (preventive) measures, Republic of Buryatia.
根据区域社会和卫生监测信息基金,截至2019年7月1日,布里亚特共和国工业企业工作人员中登记了1518例疾病,其中股份公司乌兰乌德航空工厂(以下简称U-UAP,航空工厂)占30.8%或467例,公共股份公司领土第14发电公司(以下简称TGC-14,火力发电厂)占15.7%或239例。U-UAP地区新冠肺炎发病率为871.76 /万名工人,TGC-14地区为2280.53 /万名工人。新冠肺炎防控效果评价显示,航空工厂工作人员在疫情期间采取的卫生防疫(预防)综合措施,使新冠肺炎疫情的传播控制程度是火力发电厂的2.6倍。关键词:消毒剂,新型冠状病毒感染,工业企业,卫生防疫措施,布里亚特共和国
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引用次数: 0
Introduction of information technologies at the disinfection profile enterprise by example Moscow City Disinfection Center 以莫斯科市消毒中心为例,在消毒型材企业引入信息技术
Pub Date : 2021-12-01 DOI: 10.35411/2076-457x-2021-4-68-74
Pavel Yurevich Bychkov, P. A. Mochalkin
In accordance with the national strategy "Sanitary Shield of the Country – Safety for Health," tasks were set for the analysis and assessment of risks in the field of biological safety. To do this: the Moscow City Disinfection Center is connected to a single dispatch system of the UNIT of the Department of Housing and Communal Services of Moscow, an Algorithm for working on the UNIT portal has been developed and uniform deadlines and procedure for fulfilling applications have been determined, the form of primary documentation has been determined. A unit is organized – the Unified Information and Analytical Center, whose tasks include organizing and conducting a single centralized reception, analysis and processing of incoming information (applications for unscheduled disinfection, deratization and disinsection, summary of rodent bites), generation and compilation of reports, as well as consulting support for real-time requests and appeals of the population, customers of the State Unitary Enterprise of the Moscow State Central Executive Committee, regulatory bodies through all available communication channels (telephone, e-mail, etc.). The scoring information system of assessment of a sanitary and sanitary and hygienic condition of objects is developed: apartment houses of the city of Moscow with the territories adjoining to them. The introduction of integrated work of these systems as a whole will allow organizations of the disinfection profile: to reduce the cost of deratizations, to reduce the number of disinfectants without reducing the quality of work, to avoid the excessive use of poisoned decoys, which will dramatically increase public health and safety of the population, as well as reduce the burden on the environment of the city of Moscow. Keywords: sanitary shield of the country, information and analytical center, scoring system of assessment of sanitary and epidemiological condition, electronic systems of rodent monitoring, biological safety, biological risk assessment, biological risk analysis, information support of disinfection activities, digitalization of disinfection measures.
根据"国家卫生盾牌——健康安全"国家战略,确定了分析和评估生物安全领域风险的任务。为此,莫斯科市消毒中心与莫斯科市住房和公共服务部单位的单一调度系统相连,制定了单位门户网站的工作算法,确定了完成申请的统一期限和程序,确定了主要文件的形式。成立了一个单位——统一信息和分析中心,其任务包括组织和进行单一的集中接收、分析和处理传入的信息(申请计划外消毒、除鼠和除虫,总结啮齿动物叮咬),编写和编写报告,以及为民众的实时请求和呼吁提供咨询支持。莫斯科国家中央执行委员会国家单一企业的客户,监管机构通过所有可用的沟通渠道(电话,电子邮件等)。开发了对物体的卫生和卫生状况进行评估的评分信息系统:莫斯科市的公寓及其毗邻地区。将这些系统作为一个整体进行综合工作将使消毒机构能够:降低除鼠成本,在不降低工作质量的情况下减少消毒剂的数量,避免过度使用有毒的诱饵,这将大大提高公众的健康和安全,并减轻莫斯科城市环境的负担。关键词:国家卫生防护盾,信息与分析中心,卫生与流行病学状况评估评分系统,鼠类监测电子系统,生物安全,生物风险评估,生物风险分析,消毒活动信息支持,消毒措施数字化
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引用次数: 0
Experience in organizing disinfection measures in the context of the 2020 pandemic of coronavirus infection 2020年冠状病毒感染大流行背景下组织消毒措施的经验
Pub Date : 2021-12-01 DOI: 10.35411/2076-457x-2021-4-32-39
Elena Efimovna Kudryavtseva, Leonid Semenovich Mankovich, Ekaterina Vladimirovna Ostapenko
Ensuring biosafety in the territory of the country is one of the key functions (tasks) of the state. The pandemic of a new coronavirus infection has affected absolutely all areas of human activity in all countries of the world. Approaches to prevention have not changed, but the whole country has faced a number of challenges at various levels. With a sharply increased demand for non-specific prophylaxis (including skin antiseptics and disinfectants), not all manufacturers were ready to meet the demand with a quality product. The scarcity of resources (raw materials, components, cash shortages, personnel, etc.) constrained the rapid increase in production capacity to ensure a sharply increased demand. Keywords: pandemic COVID-19, disinfectants, skin antiseptics.
确保国家境内的生物安全是国家的主要职能(任务)之一。一种新型冠状病毒感染的大流行已经影响到世界各国人类活动的所有领域。预防方法没有改变,但整个国家在各个层面都面临着一些挑战。由于对非特异性预防(包括皮肤防腐剂和消毒剂)的需求急剧增加,并非所有制造商都准备好提供高质量的产品来满足需求。资源的稀缺(原材料、零部件、现金短缺、人员等)限制了生产能力的快速增长,以确保需求的急剧增长。关键词:新型冠状病毒,消毒剂,皮肤防腐剂。
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引用次数: 0
Disinfection in public venues and transport as a way to prevent the spread of COVID-19 公共场所和交通工具的消毒是防止COVID-19传播的一种方式
Pub Date : 2021-12-01 DOI: 10.35411/2076-457x-2021-4-40-45
Leonid Vladimirovich Berezhnenko
The article addresses to the epidemiological characteristics of the SARS-CoV-2 coronavirus. It covers detailed features and ways of coronavirus infection spreading in public venues, factors that affect the viability of the Coronaviridae family viruses, and the infection after-effects for people. Methodological and technical means of processing public transport and crowded places in the context of the spread of coronavirus infection (COVID-19) analysis has been carried out. The assessment of inactivating effectiveness of the basic chemical groups of disinfectants (oxygen-active; chloactive; cationic surfactants) is presented. The features of air masses and surfaces disinfection by the ultraviolet irradiation method are described. Special aspects and factors influencing the installations quality are considered, recommendations for the use of UV emitters of various types are given. The given study presents the general concept and current requirements for disinfection measures in public venues and transport in the context of coronavirus infection spreading. Keywords: COVID-19, coronavirus SARS-CoV-2, disinfection, novel coronavirus infection, sanitary epidemic control measures, transport, public venues.
本文论述了SARS-CoV-2冠状病毒的流行病学特征。详细介绍了新型冠状病毒在公共场所传播的特点和方式,影响冠状病毒科病毒生存能力的因素,以及感染后对人的影响。开展了冠状病毒感染(COVID-19)传播背景下处理公共交通和拥挤场所的方法和技术手段分析。氧活性消毒剂基本化学基团灭活效果评价chloactive;阳离子表面活性剂)。介绍了用紫外照射法消毒气团和表面的特点。对影响安装质量的特殊方面和因素进行了分析,并对各种类型的紫外线发射器的使用提出了建议。本研究介绍了冠状病毒感染传播背景下公共场所和交通工具消毒措施的总体概念和当前要求。关键词:COVID-19,冠状病毒SARS-CoV-2,消毒,新型冠状病毒感染,卫生防疫措施,交通运输,公共场所
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引用次数: 0
Validation of the method for evaluating the efficacy of food baits against pharaoh ant colonies 食物饵料对法老蚁群的药效评价方法的验证
Pub Date : 2021-12-01 DOI: 10.35411/2076-457x-2021-4-24-32
O. Eremina, V. V. Olifer
The validation of the method for testing the effectiveness of food baits against colonies of the Pharaoh ant using experiments with commercially produced and laboratory-prepared sugar baits containing insecticides from different chemical groups was carried out. We studied baits based on boron compounds (boric acid and sodium tetraborate), neonicotinoids (thiamethoxam, imidacloprid, and acetamiprid), oxadiazines (indoxacarb), phenylpyrazoles (fipronil), carbamates (methomyl), pyrroles (chlorfenapyr) amidinohydrazones (hydramethylnon), avermectins (abamectin), and insect growth regulators (pyriproxyfen). The proposed algorithm for conducting experiments covers the whole variety of active ingredients of insecticides used in baits. The verification of several dozen products intended for the elimination of colonies of the Pharaoh ant has shown that most of the products are suitable for the requirements for efficacy indices. Keywords: Pharaoh ant, insecticidal baits.
利用商业生产和实验室制备的含不同化学基团杀虫剂的糖饵,验证了测试食物诱饵对法老蚁群体的有效性的方法。我们研究了含硼化合物(硼酸和四硼酸钠)、新烟碱类(噻虫嗪、吡虫啉和啶虫啉)、恶二嗪类(茚虫卡威)、苯吡唑类(氟虫腈)、氨基甲酸酯类(灭多威)、吡咯类(氯虫腈)、脒酰腙类(羟甲基农)、阿维菌素类(阿维菌素)和昆虫生长调节剂(吡丙醚)的诱饵。所提出的实验算法涵盖了诱饵中所用杀虫剂的全部有效成分。对几十种用于消灭法老蚁菌落的产品进行了验证,结果表明,大多数产品都符合功效指标的要求。关键词:法老蚁;杀虫诱饵;
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引用次数: 0
Reform of control and supervisory activities. Changes in the regulatory framework for disinfection activities 改革控制和监督活动。改变消毒活动的规管架构
Pub Date : 2021-12-01 DOI: 10.35411/2076-457x-2021-4-74-79
Pavel Aleksandrovich Deminov, P. A. Mochalkin
The reform of control and supervisory activities intended to exclude old and irrelevant acts and outdated norms, fix accurate and understandable rules, as well as exclude unreasonable and redundant norms in various areas. It was called the “regulatory guillotine" and involves a complete revision of the mandatory requirements for business. Comparison the SanPiN 3.3686-21 “Sanitary and epidemiologic requirements for prevention of infectious diseases" with earlier existing health regulations in the field of disinfection, disinsection, deratization was made. Changes in the regulatory framework in the field of disinfection activities are a necessity and a fait accompli. SanPiNs contain requirements, and their compliance can be verified by the relevant supervisory authorities. Reducing the number of requirements corresponds to the goals set by the reform - this will reduce the administrative burden on business and supervisory authorities. Keywords: reform of control and supervision activities, regulatory guillotine, changes in legislation, disinfection activities, legal acts in the field of disinfectology.
管制和监督活动的改革旨在排除旧的和不相关的行为和过时的规范,确定准确和可理解的规则,以及排除各领域不合理和多余的规范。它被称为“监管断头台”,涉及对企业强制性要求的全面修订。将三品3.3686-21《传染病预防卫生流行病学要求》与我国现行的消毒、除虫、除鼠卫生法规进行比较。改变消毒活动领域的监管框架是必要的,也是既成事实。sanpin包含要求,其合规性可以通过相关监管机构进行验证。减少要求的数量符合改革的目标,这将减轻企业和监管部门的行政负担。关键词:监管活动改革,监管断头台,立法变化,消毒活动,消毒领域法律行为
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引用次数: 0
Evaluation of the sensitizing effect of a disinfectant based on glutaraldehyde upon inhalation 戊二醛类消毒剂吸入致敏效果评价
Pub Date : 2021-12-01 DOI: 10.35411/2076-457x-2021-4-19-24
G. P. Pankratova, Z. К. Shaikhutdinova, Tatyana Nikolaevna Potapova, M. V. Bidevkina
When investigating new disinfectants, it is necessary to assess the degree of their danger by modeling the conditions of use. As is known, the main danger of disinfectants, especially volatiles, is posed by the inhalation route of entry into the body, exerting an irritating effect on the respiratory organs, as well as a general toxic and sensitizing effect. Despite reasonable restrictions on the use of disinfectants from the aldehyde class for decontamination of the surfaces of premises and equipment, state registration receives disinfectants based on glutaraldehyde (GA), intended for wide use in various areas, including everyday life, which is unacceptable. Experiments were carried out to confirm the danger of using GA-based disinfectants. Sensitizing effect of GA-based disinfectant under conditions of surface treatment by rubbing method is studied. Significant release of GA into the air after surface treatment (27.7±4.1 mg/m3) was detected. The concentration of GA in the air decreased by 4.5 times after 6 hours of ventilation. The sensitizing effect of the GA-based agent was determined on guinea pigs by a provocative ear swelling test and a leukocyte specific lysis reaction. The results of the study indicate a pronounced sensitizing effect of the agent. Keywords: glutaraldehyde, toxicity, disinfectants, disinfection, sensitization, inhalation, guinea pigs.
在研究新的消毒剂时,有必要通过模拟使用条件来评估其危险程度。众所周知,消毒剂,特别是挥发物的主要危险是通过吸入途径进入人体,对呼吸器官产生刺激作用,以及一般的毒性和致敏作用。尽管对使用乙醛类消毒剂对房屋和设备表面进行净化有合理的限制,但国家注册收到的基于戊二醛(GA)的消毒剂,旨在广泛用于各个领域,包括日常生活,这是不可接受的。实验证实了使用ga基消毒剂的危险性。研究了摩擦法表面处理条件下ga基消毒剂的增敏效果。经表面处理后,GA向空气中显著释放(27.7±4.1 mg/m3)。通气6小时后,空气中GA的浓度下降了4.5倍。通过刺激耳肿胀试验和白细胞特异性裂解反应,确定了ga基制剂对豚鼠的致敏作用。研究结果表明,该剂有明显的增敏作用。关键词:戊二醛,毒性,消毒剂,消毒,致敏,吸入,豚鼠
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引用次数: 0
Problems of disinfectological provision of the population in the pandemic period of COVID-19 infection in the Republic of Moldova 摩尔多瓦共和国COVID-19感染大流行期间人口消毒用品供应问题
Pub Date : 2021-12-01 DOI: 10.35411/2076-457x-2021-4-45-51
V. Tsurkan
The principles of organizing and implementing anti-epidemic, including disinfectological measures for COVID-19 infection were studied, and the results of the state of readiness of interested services in the localization and elimination of focuses of coronavirus infection were presented. It was noted that the untimely solution of existing problems of a socio-economic nature contributed to the development of the pandemic process of COVID-19 infection. In the initial period of the development of the pandemic in most countries of the world, including Moldova, the system for monitoring and actively detecting cases of the population of COVID-19 did not work. Lack of disinfection services and insufficiently trained disinfectologists lead to untimely and poor-quality disinfection measures. The role of the disinfectological service in ensuring the epidemiological well-being of the population is argued. The necessity of creating a new, comprehensive system for protecting the country’s population from especially dangerous infectious diseases has been substantiated. Keywords: disinfection measures, biocides, treatment and prevention organizations, pandemic process, technologies, methods, forces and means, provision, infectious diseases, COVID-19 infection
研究了组织实施新型冠状病毒感染消毒等防疫措施的原则,并介绍了相关服务机构在定位和消除新型冠状病毒感染焦点方面的准备情况。各方注意到,未能及时解决现有社会经济问题,加剧了新冠肺炎疫情蔓延进程。在包括摩尔多瓦在内的世界大多数国家大流行发展的初期,监测和主动发现COVID-19人口病例的系统没有发挥作用。缺乏消毒服务和缺乏训练有素的消毒人员导致消毒措施不及时和质量差。论述了消毒服务在确保人口流行病健康方面的作用。有必要建立一个新的、全面的系统,以保护我国人民免受特别危险的传染病的侵害。关键词:消毒措施、杀菌剂、防治组织、大流行过程、技术、方法、力量和手段、供应、传染病、COVID-19感染
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引用次数: 0
Safety assessment of residual amounts of disinfectants based on quaternary ammonium compounds on medical devices 基于季铵化合物的医疗器械消毒剂残留量的安全性评价
Pub Date : 2021-09-01 DOI: 10.35411/2076-457x-2021-3-36-39
A. L. Karaev, M. V. Bidevkina, M. V. Matrosenko
Has been made an assessment of the toxicity of residual amounts of disinfectants after using them on products, made from various materials, with DS solutions based on QAC. The working solutions were used in concentrations from 0.3 to 7 % (by DV). The safety of the studied samples was assessed by the toxicity index "It" (in%) on an AT-05 Image Analyzer. Washing out of the residual amounts of DS in concentrations of 0.3–0.7 % (by DW) did not significantly affect the total time of disinfection treatment or pre-sterilization cleaning. At higher concentrations of solutions, there were differences in the time of washing test items and dishes for receiving safe amounts of DS. It is concluded that it is inexpedient to use solutions based on QAC in a concentration of more than 4.5 % (in terms of DV) for disinfection treatment and pre-sterilization cleaning of products made of natural and silicone rubber. Keywords: disinfectants, quaternary ammonium compounds, product washing, AT-05 image analyzer, to­xicity index.
采用基于质量质量体系的DS溶液,对不同材质产品使用后消毒剂残留量的毒性进行了评估。工作液的浓度为0.3 ~ 7%(以DV计)。在AT-05图像分析仪上用毒性指数“It”(%)评价所研究样品的安全性。洗涤出浓度为0.3 - 0.7%(以DW计)的DS残留量对消毒处理或灭菌前清洗的总时间没有显著影响。在较高浓度的溶液中,洗涤测试项目和盘子的时间存在差异,以获得安全量的DS。结论:对于天然橡胶和硅橡胶制品,不宜采用浓度大于4.5% (DV)的QAC溶液进行消毒处理和灭菌前清洗。关键词:消毒剂,季铵类化合物,产品洗涤,AT-05图像分析仪,毒性指数
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引用次数: 0
期刊
Disinfection affairs
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