Domestic animal endocrinology最新文献

{"title":"Exploring the relationship between plasma and salivary levels of oxytocin, vasopressin, and cortisol in beagles: A preliminary study","authors":"Youngwook Jung ,&nbsp;Kayoung Yang ,&nbsp;Minjung Yoon","doi":"10.1016/j.domaniend.2025.106937","DOIUrl":"10.1016/j.domaniend.2025.106937","url":null,"abstract":"<div><div>Oxytocin, vasopressin, and cortisol are widely used as biomarkers to assess the temperament or emotional state of dogs. Typically, these levels are measured in blood; however, this invasive procedure can induce acute pain and stress. Considering the welfare of dogs, it is necessary to replace these procedures with noninvasive methods. Saliva sampling has emerged as a promising, noninvasive alternative for measuring hormonal levels. Nonetheless, it remains unclear whether saliva samples accurately reflect plasma hormonal levels in dogs. The objective of this study was to evaluate the correlations of oxytocin, vasopressin, and cortisol levels between plasma and saliva samples. We simultaneously collected blood and saliva samples from fifteen beagles, aged six, including eleven females and four sterilized males. Due to the limited availability of saliva samples, each analysis was performed on 5–11 dogs. Hormonal levels were quantified using commercial ELISA kits. Linear regression analysis and Pearson's correlation coefficient were used for statistical analysis. Our findings revealed no significant correlation between oxytocin or vasopressin levels in the plasma and salivary samples. However, a significant positive correlation was observed between cortisol levels in plasma and saliva samples. Additionally, oxytocin and vasopressin levels were positively correlated in both plasma and saliva samples. A positive correlation was found between the plasma cortisol and oxytocin levels, whereas no correlation was observed between the salivary cortisol and oxytocin levels. This study provides a foundation for understanding hormonal relationships across different matrices, contributing to the development of alternative sampling methods that prioritize animal welfare.</div></div>","PeriodicalId":11356,"journal":{"name":"Domestic animal endocrinology","volume":"92 ","pages":"Article 106937"},"PeriodicalIF":1.9,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synchronization of follicular wave before superovulation in dromedary camel by means of transvaginal follicle ablation","authors":"B Asadi ,&nbsp;F Seyedasgari ,&nbsp;R Ebadi","doi":"10.1016/j.domaniend.2025.106935","DOIUrl":"10.1016/j.domaniend.2025.106935","url":null,"abstract":"<div><div>The synchronization of follicular waves prior to the initiation of superovulation is a prerequisite for successful results. This study investigates the feasibility of applying transvaginal follicle ablation (TFA) as an alternative to hormonal treatments for synchronization in dromedary camels.</div><div>In experiment 1, the follicular cycle of pre-synchronized and naturally cycling camels (<em>n</em> = 24) was monitored and all structures &gt; 4 mm were ablated in subgroups of animals (<em>n</em> = 4 each) at early, mid, and late stages of the follicular cycle. The appearance and characteristics of the next follicular wave as well as the occurrence and the fate of residual structures were investigated. In experiment 2, sixteen camels were used for superovulation subsequent to follicle ablation or conventional hormonal synchronization in a changeover design and the result of superovulation was compared among the methods. A subset of 88 embryos was transferred to recipients and pregnancy rates and pregnancy loss rates were compared between the synchronization methods.</div><div>On average, more structures were ablated from naturally cycling camels than pre-synchronized camels. Ablation of larger structures (&gt; 10 mm) resulted in the formation of remnant structures (26.1 %) out of which 52.9 % showed structural and functional luteinization. The next follicular cohort emerged at day 2.16 ± 0.20 and 2.33 ± 0.22 after the ablation, and established dominance at day 9.33 ± 0.35 and 9.16 ± 0.32, in naturally cycling and pre-synchronized animals, respectively, with no significant difference among them (<em>P</em> &gt; 0.05). All camels responded to ovulation induction at day 14 while camels ablated at mid-cycle had smaller follicles (12.88 ± 0.46 mm) at this time point compared to camels ablated at dominance or early cycle (14.13 ± 0.70 and 14.81 ± 0.42 mm, respectively; <em>P</em> &lt; 0.05). A similar number of developed follicles prior to mating (13.81 ± 1.62 vs. 15.12 ± 1.65), corpus luteum (9.75 ± 1.24 vs. 10.43 ± 1.35), transferable (7.56 ± 1.06 vs. 8.50 ± 1.30), and spherical embryos (5.87 ± 1.07 vs. 6.12 ± 089) were obtained in synchronized camels by hormonal and TFA methods, respectively (<em>P</em> &gt; 0.05). Embryos of the TFA group showed a trend for higher embryonic loss rate after transfer compared to the hormonally synchronized group (34.4 % vs. 17.2 %, <em>P</em> &lt; 0.10).</div><div>In conclusion, follicle ablation was followed by the development of a new follicular wave capable of establishing dominance and ovulation, irrespective of the stage of the follicular cycle in which the procedure is undertaken, and can be used as an alternative way of synchronization in dromedary camels.</div></div>","PeriodicalId":11356,"journal":{"name":"Domestic animal endocrinology","volume":"92 ","pages":"Article 106935"},"PeriodicalIF":1.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alpha-synuclein expression in anterior pituitary cells of aged cattle","authors":"Yvan Bienvenu Niyonzima,&nbsp;Denis Karani Wanjiru,&nbsp;Yuuki Asato,&nbsp;Hiroya Kadokawa","doi":"10.1016/j.domaniend.2025.106936","DOIUrl":"10.1016/j.domaniend.2025.106936","url":null,"abstract":"<div><div>The anterior pituitary (AP) gland must function properly for homeostasis and fertility; however, aging suppresses AP function via unclear mechanisms. α-synuclein is a protein encoded by the <em>SNCA</em> gene. Its monomers aggregate to the fibril form, which causes brain disease as age advances. Importantly, fibril α-synuclein propagates among neurons akin to prions. Recently, we discovered α-synuclein expression in oxytocin neurons and gonadotrophin-releasing hormone (GnRH) neurons in bovine hypothalamus. However, whether α-synuclein propagates into gonadotrophs remains unclear. We tested the hypothesis that α-synuclein expression in AP glands of aged cows is different from that of healthy heifers. We analyzed mRNA and protein levels and performed fluorescent immunohistochemistry for luteinizing hormone, follicle-stimulating hormone, GnRH receptor, and α-synuclein, followed by confocal microscopy with Congo red staining to detect amyloid deposits. Presence of synuclein was confirmed in AP tissues by both mRNA and protein levels in both heifers and old cows. Western blots showed several bands of α-synuclein, probably reflecting monomer, dimer, and oligomers, in the AP tissues of both heifers and old cows. Confocal microscopy revealed that most gonadotrophs were positive for both α-synuclein and Congo red in the old group, but not in the young group. In addition, α-synuclein expression was detected in the immortalized gonadotrophs, LβT2 cells, and in the majority of aged bovine corticotrophs, lactotrophs, somatotrophs, and thyrotrophs. In conclusion, the majority of gonadotrophs and other AP cell types were positive for α-synuclein and amyloid deposits in the old group, but not in the young group.</div></div>","PeriodicalId":11356,"journal":{"name":"Domestic animal endocrinology","volume":"92 ","pages":"Article 106936"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143561716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression pattern of sex steroid hormone receptors in the adult male rabbit brain","authors":"Ignacio Camacho-Arroyo ,&nbsp;Karina Hernández-Ortega ,&nbsp;Karla Mariana Peña-Gutiérrez ,&nbsp;Laura Noemi Hernández-Lúa ,&nbsp;Beatriz Arantxa Castro-Reyes ,&nbsp;Gabriela González-Mariscal","doi":"10.1016/j.domaniend.2025.106922","DOIUrl":"10.1016/j.domaniend.2025.106922","url":null,"abstract":"<div><div>Progesterone (P4), estradiol (E2), and testosterone (T) are crucial for reproduction and are pivotal in several vertebrate central nervous system (CNS) functions. These hormones act by binding to their corresponding receptors, including those intracellularly located, such as progesterone receptor (PR), estrogen receptor (ER), and androgen receptor, which in this manuscript we named testosterone receptor (TR). The expression pattern of these receptors in the rabbit male brain is unknown. We studied PR, ER, and TR expression at mRNA and protein levels in several intact adult male brain regions by RT-qPCR and Western blot. We found the highest PR mRNA levels in the prefrontal cortex (PC) and the preoptic area (POA). PR protein content (110 kDa) was similar in all the analyzed brain regions. Maximum ERα mRNA levels were found in the mesencephalon (MSC) compared with the scarce levels presented in POA and cerebellum (CER). The two leading ERα bands (54 and 66 kDa) showed comparable content among analyzed brain regions, except in the olfactory bulb (OB). Considerable TR mRNA levels were found in the analyzed brain areas except in CER. TR protein (110 kDa) content was also high in MSC. The CER showed the lowest PR, ERα, and TR mRNA levels, but the corresponding protein contents were similar to those of different areas. These data reflect regional variability in the expression of sex steroid hormone receptors in the adult male rabbit brain. They constitute the basis for defining the distribution pattern of these receptors in the rabbit brain; in addition, they would allow comparisons to be made with reports of the expression of these receptors in female rabbit brains and the search for understanding their role in rabbits.</div></div>","PeriodicalId":11356,"journal":{"name":"Domestic animal endocrinology","volume":"92 ","pages":"Article 106922"},"PeriodicalIF":1.9,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating hair cortisol dynamics in German Shepherd Dogs throughout pregnancy, lactation, and weaning phases, and its potential impact on the hair cortisol of offspring","authors":"Caixia Pan,&nbsp;Shu Xu,&nbsp;Wencai Zhang,&nbsp;Yu Zhao,&nbsp;Mingqiang Song,&nbsp;Jianli Zhao","doi":"10.1016/j.domaniend.2025.106921","DOIUrl":"10.1016/j.domaniend.2025.106921","url":null,"abstract":"<div><div>Pregnancy, lactation, and weaning are crucial physiological stages in the life of bitches, directly affecting the physiological health of bitches and the growth and development of newborn puppies. This study aims to investigate the physiological stress of bitches during pregnancy, lactation, and weaning, as well as the effects of these changes on newborn puppies, by analyzing the variations in hair cortisol concentrations (HCCs) of bitches and their newborn offspring during different stages. This study selected 24 female German Shepherd dogs aged 2-3 years who were pregnant and giving birth for the first time and their 118 surviving newborn offspring as experimental subjects. Hair samples were collected from the right shoulder and neck of the bitches and their offspring at four key time points: the day of mating (T0), the day of delivery (T1/NT1), the first day of weaning (T2/NT2), and the 60th day after weaning (T3/NT3). The HCCs was detected by enzyme-linked immunosorbent assay (ELISA) to assess their physiological stress. The results showed that the maternal HCCs significantly increased during pregnancy and lactation, reaching a peak during lactation. The HCCs of puppies also significantly increased during the weaning period. Meanwhile, there was a significant but moderate correlation between the cortisol levels in maternal hair and puppies' hair during pregnancy and lactation. In addition, the maternal HCCs during pregnancy and lactation were affected by the litter size, the higher the litter size, the higher the hair cortisol level, while the cortisol levels in the hair of puppies were not affected by the litter size. Bitches may face higher physiological and psychological pressures during reproduction and nurturing offspring, especially when the litter size is large. At the same time, the physiological status of bitches may have a certain impact on puppies. Therefore, care and attention during pregnancy, lactation, and puppy weaning periods should be strengthened to ensure that bitches and puppies receive good feeding management and environmental support, maintain their physiological and psychological health, and further enhance animal welfare.</div></div>","PeriodicalId":11356,"journal":{"name":"Domestic animal endocrinology","volume":"92 ","pages":"Article 106921"},"PeriodicalIF":1.9,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143422534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increasing cervical penetrability in sheep by long-acting treatments with oxytocin (Carbetocin) and/or prostaglandin E2 (Dinoprostone)","authors":"M. Rodríguez-Piñón ,&nbsp;D. Casuriaga ,&nbsp;G. García-Barcelo ,&nbsp;D. Fila ,&nbsp;J. Gil","doi":"10.1016/j.domaniend.2025.106920","DOIUrl":"10.1016/j.domaniend.2025.106920","url":null,"abstract":"<div><div>The aim was to study the effect of long-acting treatments with oxytocin (Carbetocin, Cb) and/or prostaglandin E2 (Dinoprostone, Dp) on cervical penetrability and collagenolysis in synchronized ewes (12 days MAP-eCG). At 42 h post eCG, ewes were treated with Cb (Group Cb, <em>n</em> = 6, 40 μg, i.m., Decomotón, Laboratorios Callier, Uruguay); Dp (Group Dp, <em>n</em> = 10, 10 mg, slow-release intravaginal device, Propess®, Ferring Pharmaceuticals Ltd., West Drayton, UK); combined Cb and Dp treatment (Group Cb+Dp, <em>n</em> = 8) and saline solution i.m. and a placebo intravaginal device (Group C, <em>n</em> = 10). Cervical penetrability increased from 0 h to 42 h post eCG (<em>P</em> &lt; 0.003) in all groups, then decrease in Group C (<em>P</em> &lt; 0.03) from 42 to 68 h post eCG, whereas remained unchanged in Groups Cb and Cb+Dp or increase at 54 h post eCG in Group Dp (<em>P</em> &lt; 0.05). Thus, there was higher cervical penetrability in treated groups than Group C at the expected time of artificial insemination (54 h post eCG). At 54 h post eCG, collagen concentration was lower in Group Cb than in the others groups (<em>P</em> &lt; 0.05), whereas the ratio between the activity of the activated and latent forms of MMP-2 was greater in Groups Cb and Cb+Dp than in Group C (<em>P</em> &lt; 0.05). The increasing cervical penetrability induced by Cb, but not by Dp, could be explained by an increase in MMP-2-dependent collagen degradation. Furthermore, combined treatment with Cb and Dp did not enhance the effects induced by each hormone administered separately.</div></div>","PeriodicalId":11356,"journal":{"name":"Domestic animal endocrinology","volume":"91 ","pages":"Article 106920"},"PeriodicalIF":1.9,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Granulosa cell function in domestic animals: A review on the in vitro effects of FSH, insulin and insulin-like growth factor 1","authors":"Leon J. Spicer ,&nbsp;Excel Rio S. Maylem ,&nbsp;Luis Fernando Schütz","doi":"10.1016/j.domaniend.2025.106919","DOIUrl":"10.1016/j.domaniend.2025.106919","url":null,"abstract":"<div><div>Ovarian granulosa cells produce a variety of biologically active compounds in addition to steroid hormones that include numerous families of growth factors, cytokines and adipokines. Many of these function as endocrine, paracrine and autocrine hormones to regulate ovarian activity. The goal of this review is to provide an update on the evidence in domestic animals on how FSH, insulin and IGF1 regulate the function of granulosa cells with a focus on ovarian steroidogenesis and cell proliferation with comparisons across six domestic animals: pigs, cattle, horses, water buffalo, goats and sheep. In most species, FSH was not a mitogenic stimulus to granulosa cells whereas insulin and IGF1 were stimulatory to cell proliferation in the species it was evaluated. FSH, insulin and IGF1 were all stimulatory to granulosa cell steroidogenesis in the species it was studied. More research is needed to evaluate the role of insulin in the regulation of cell proliferation and steroidogenesis in water buffalo and goats. The role of IGF1 in regulating granulosa cell function in horses also needs further study. Most granulosa-cell secreted factors have direct effects (either positive or negative) on FSH-, insulin- and IGF1-induced steroid production in ovarian cells, but how they all work together to create a cumulative effect to regulate fertility will require further research.</div></div>","PeriodicalId":11356,"journal":{"name":"Domestic animal endocrinology","volume":"91 ","pages":"Article 106919"},"PeriodicalIF":1.9,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gonadotropins, local factors and a variety of adipokines contribute to regulate swine granulosa cell function","authors":"G. Basini,&nbsp;F. Grasselli","doi":"10.1016/j.domaniend.2025.106918","DOIUrl":"10.1016/j.domaniend.2025.106918","url":null,"abstract":"<div><div>This paper reviews the role of endocrine regulators in swine ovarian cell functions, highlighting the intricate hormonal interactions that drive reproductive and metabolic processes. The pig represents a valuable model for human biology due to physiological and anatomical similarities. Understanding the endocrine mechanisms in swine can provide insights about human reproductive health and metabolic disorders. The present review describes some key hormones involved, including gonadotropins, sex steroids, and adipokines, and their impacts on ovarian folliculogenesis and steroidogenesis. Emphasis is placed on the crosstalk between the ovary and adipose tissue, which is critical for maintaining reproductive and metabolic homeostasis.</div></div>","PeriodicalId":11356,"journal":{"name":"Domestic animal endocrinology","volume":"91 ","pages":"Article 106918"},"PeriodicalIF":1.9,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utero-placental adaptations in response to intrauterine growth restriction in swine","authors":"Morgan S. Clemens ,&nbsp;Maria F. Tyree ,&nbsp;Claire Stenhouse","doi":"10.1016/j.domaniend.2025.106917","DOIUrl":"10.1016/j.domaniend.2025.106917","url":null,"abstract":"<div><div>Intrauterine growth restriction (IUGR) is a common condition in swine associated with high piglet mortality and morbidity that develops in early gestation. This review article explores differences in uterine and placental tissues associated with IUGR fetuses compared to their normally-grown littermates at different stages of gestation. Specifically, we will review the available knowledge to date describing differences in 1) structure, 2) cellular apoptosis and proliferation, 3) adhesion, and 4) angiogenesis in endometrial and placental tissues associated with IUGR fetuses across gestation. Improved understanding of the mechanisms regulating IUGR is essential for the development of strategies to minimize the impact of IUGR in swine operations, thus improving reproductive efficiency and animal welfare.</div></div>","PeriodicalId":11356,"journal":{"name":"Domestic animal endocrinology","volume":"91 ","pages":"Article 106917"},"PeriodicalIF":1.9,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fish oil a source of omega-3 fatty acids affects hypothalamus heat resistance genes expressions and fatty acid composition in heat-stressed chicks","authors":"Hatem M. El-Tahan ,&nbsp;Chun Ik Lim ,&nbsp;Ahmad R. Alhimaidi ,&nbsp;Aiman A. Ammari ,&nbsp;Sungbo Cho ,&nbsp;In Ho Kim ,&nbsp;Hossam M. El-Tahan","doi":"10.1016/j.domaniend.2025.106915","DOIUrl":"10.1016/j.domaniend.2025.106915","url":null,"abstract":"<div><div>This study investigated the effects of fish oil (FO) supplementation on the hypothalamus heat resistance gene expressions and fatty acid composition of chicks under acute high-temperature stress, for treating Cholestasis. A total of 48 chicks (Ross 308) at age of 14 days were acclimatized to corn oil or FO (n = 24 for each) by oral gavaging for 10 days, and then subjected to heat stress (35 ± 1 °C, HT) for 3 h or maintained at the normal temperature (26 ± 1 °C, NT) as grouped as NT and FO-NT control and HT and FO-HT (n = 12 for each).. The results showed that FO supplementation had no significant (P &gt; 0.05) effect on feed intake or body weight. The FO-HT group exhibited (<em>P</em> <em>&lt;</em> <em>0.05</em>) a lower rectal temperature, and plasma interleukin-6 (IL-6), triglyceride and corticosterone levels, in accompany with lower expressions of hypothalamic adenine nucleotide translocators (ANT) and uncoupling protein (UCP) but increased (<em>P</em> <em>&lt;</em> <em>0.05</em>) plasma superoxide dismutase activity and hypothalamic neuropeptide-Y (NPY) and heat shock protein-70 (HSP-70) expressions.. Additionally, the FO-HT group (P &lt; 0.05) demonstrated a higher unsaturated fatty acid/saturated fatty acid (UFA/SFA) ratio in the breast muscle. These findings suggest that FO supplementation can enhance the heat resistance of broiler chicks under acute heat stress and alter the fatty acid composition of their breast muscle. However, further studies are needed to determine whether desirable fatty acids can cross the blood-brain barrier and their implications for human health.</div></div>","PeriodicalId":11356,"journal":{"name":"Domestic animal endocrinology","volume":"91 ","pages":"Article 106915"},"PeriodicalIF":1.9,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}