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Fear of hypoglycemia and disordered eating behavior in type 1 diabetes 1型糖尿病患者对低血糖的恐惧和饮食行为紊乱
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-18 DOI: 10.1016/j.eatbeh.2025.102044
Max Z. Roberts , Caitrin Murphy , Ashley A. Moskovich , Francesca A. Scheiber , Rhonda M. Merwin
Individuals with type 1 diabetes (T1D) are at elevated risk for disordered eating behaviors (DEBs). When DEBs occur in someone with T1D, they have severe consequences, including increased risk of diabetes-related medical complications and early mortality related to poor glycemic control. Fear of hypoglycemia (FoH) is a diabetes-specific factor that is assumed to play a role in DEBs in T1D, but this has not been adequately tested. The current study examined FoH as a predictor of DEBs in the natural environment in adults with T1D who met criteria for clinically significant DEBs. Participants (n = 59) completed the 18 item FoH worry subscale of the Hypoglycemia Fear Survey II and reported on their eating behavior over three days of ecological momentary assessment. A total of 737 eating episodes were reported; 235 (31.89%) eating episodes involved DEBs (overeating or binge eating). The proportion of eating episodes that involved DEBs was regressed on FoH, controlling for age. Every one-point increase in the FoH worry subscale score was associated with a 2% increase in the odds of DEB (OR = 1.02; 95% CI [1.01, 1.03], p < .001). Results suggest that FoH may be an important clinical factor when addressing DEBs in T1D.
1型糖尿病(T1D)患者发生饮食失调(DEBs)的风险较高。当糖尿病1型糖尿病患者发生deb时,会产生严重后果,包括糖尿病相关并发症的风险增加以及与血糖控制不良相关的早期死亡。对低血糖的恐惧(FoH)是一种糖尿病特异性因素,被认为在T1D患者的deb中起作用,但尚未得到充分的验证。目前的研究检查了FoH作为自然环境中符合临床显著DEBs标准的T1D成人DEBs的预测因子。参与者(n = 59)完成了低血糖恐惧调查II的18项FoH担忧子量表,并报告了他们在三天的生态瞬时评估中的饮食行为。共报告了737例进食事件;235例(31.89%)进食事件涉及DEBs(暴饮暴食或暴食)。在控制年龄的情况下,进食事件中涉及DEBs的比例在FoH上回归。FoH忧虑亚量表得分每增加1分,DEB的几率就增加2% (OR = 1.02; 95% CI [1.01, 1.03], p < 0.001)。结果表明,FoH可能是解决T1D患者DEBs的重要临床因素。
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引用次数: 0
Body appreciation as an indirect pathway in the association between health values and eating behaviors among college students 身体欣赏在大学生健康价值观与饮食行为之间的间接作用。
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-17 DOI: 10.1016/j.eatbeh.2025.102043
Sheida Zeraattalab-Motlagh , Cynthia Yoon , Craig Johnston , Aliye B. Cepni , Tracey Ledoux
Although the association between health values and eating behaviors has been shown in previous research, its underlying mechanism remains unclear, especially among US college students. Guided by Self-Determination Theory, this cross-sectional study examined direct and indirect associations between health values and eating behaviors through body appreciation. In total, 2425 students (58 % women; mean age = 20.3 years) participated during Fall 2022 and Spring 2023. Pearson's correlation coefficient and PROCESS macro were applied to assess relationships between health values, body appreciation and eating behaviors (intuitive eating and emotional eating). Health values were divided into values for physical health (VPH) and values for social and emotional health (VSEH). Results indicated that VPH was positively related to intuitive eating and negatively related to emotional eating, both directly (βintuitive eating = 0.15, βemotional eating = −0.08, P < 0.001) and indirectly via body appreciation (βintuitive eating = 0.09 (95 % confidence interval (CI): 0.08, 0.12; βemotional eating = −0.09, 95 %CI: −0.11, −0.07). VPSH was directly (βintuitive eating = 0.11, P < 0.001) and indirectly (βintuitive eating = 0.09, 95 %CI: 0.07, 0.11) related to higher intuitive eating, while indirectly reducing emotional eating via body appreciation (βemotional eating = −0.09, 95 %CI: −0.12, −0.08), with no direct association. This study highlights that health values were positively related to intuitive eating and negatively related to emotional eating, and body appreciation explained at least some of these relationships. These findings provide foundation for future longitudinal studies to investigate whether health values predict the development of eating behaviors through changes in body appreciation.
虽然健康价值观和饮食行为之间的联系已经在之前的研究中得到证实,但其潜在机制尚不清楚,尤其是在美国大学生中。在自我决定理论的指导下,本横断面研究通过身体欣赏来检验健康价值观与饮食行为之间的直接和间接联系。共有2425名学生(58%为女性,平均年龄为20.3岁)参加了2022年秋季和2023年春季的研究。运用Pearson相关系数和PROCESS宏来评估健康价值观、身体欣赏与饮食行为(直觉性饮食和情绪性饮食)之间的关系。健康价值分为身体健康价值(VPH)和社会和情感健康价值(VSEH)。结果表明,VPH与直观饮食呈正相关,与情绪饮食呈负相关,均为直接相关(β直观饮食= 0.15,β情绪饮食= -0.08,P直观饮食= 0.09)(95%置信区间(CI): 0.08, 0.12;β情绪化进食= -0.09,95% CI: -0.11, -0.07)。VPSH与高直觉进食有直接关系(β直觉进食= 0.11,P直觉进食= 0.09,95% CI: 0.07, 0.11),而通过身体欣赏间接降低情绪性进食(β情绪进食= -0.09,95% CI: -0.12, -0.08),无直接关联。这项研究强调,健康价值观与直觉性饮食呈正相关,与情绪性饮食负相关,而身体欣赏至少解释了其中的一些关系。这些发现为未来的纵向研究提供了基础,以探讨健康价值观是否通过身体欣赏的变化来预测饮食行为的发展。
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引用次数: 0
Diagnostic evolution and symptomatic development of eating disorders: A retrospective study 饮食失调的诊断演变和症状发展:一项回顾性研究
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-17 DOI: 10.1016/j.eatbeh.2025.102042
Jiajia Zhang , Zheyu Lin , Ning Zhang , Huifen Qiao , Changjun Teng

Objective

Diagnoses of eating disorders often evolve over time, yet research in China is scarce. Thus, this study aims to explore the evolution of eating disorder diagnoses and symptom development characteristics in the Chinese cultural context through high-quality retrospective examination, and to analyze risk factors for common symptom development.

Method

A retrospective analysis of patients diagnosed with eating disorders from 2019 to 2024 with a disease course exceeding two years. Data on age at onset, BMI, symptom onset, and other relevant variables were collected by reviewing outpatient medical records to determine longitudinal symptom progression and diagnostic shifts. A multifactorial cox proportional hazards model was constructed incorporating variables such as age of onset, sex, family history, self-harm, and amenorrhea to predict binge eating in restrictive eating disorder.

Result

Among 128 outpatients with eating disorders, 50.8 % experienced diagnostic shifts, predominantly from restrictive anorexia to binge-purge types, with complex symptom evolution in the majority. Survival analysis indicates that self-harm behavior significantly affects survival time compared to no self-harm (HR = 1.534, 95 %CI = 1.012–2.325, p = 0.044), and amenorrhea significantly affects survival time compared to no amenorrhea (HR = 0.565, 95 % CI = 0.373–0.855, p = 0.007).

Conclusion

In the Chinese cultural context, diagnostic shifts and symptom overlaps across eating disorder subtypes are observed, potentially indicating a natural progression of clinical phenomena. Assessment of self-harm and amenorrhea is crucial in the early diagnosis and treatment of eating disorders, particularly in patients with restrictive eating behaviors.
饮食失调的诊断往往随着时间的推移而发展,但在中国的研究很少。因此,本研究旨在通过高质量的回顾性调查,探讨中国文化背景下饮食失调诊断和症状发展特征的演变,并分析常见症状发展的危险因素。方法回顾性分析2019 - 2024年诊断为饮食失调且病程超过2年的患者。通过回顾门诊病历,收集发病年龄、BMI、症状发作和其他相关变量的数据,以确定纵向症状进展和诊断转变。建立多因素cox比例风险模型,纳入发病年龄、性别、家族史、自残、闭经等变量,预测限制性饮食障碍患者的暴食行为。结果128例进食障碍门诊患者中,50.8%的患者出现了从限制性厌食症到暴泻型的诊断转变,以复杂的症状演变为主。生存分析显示,自残行为与无自残行为相比显著影响生存时间(HR = 1.534, 95% CI = 1.012-2.325, p = 0.044),闭经与无闭经相比显著影响生存时间(HR = 0.565, 95% CI = 0.373-0.855, p = 0.007)。结论在中国文化背景下,饮食失调亚型的诊断转变和症状重叠,可能表明临床现象的自然发展。自我伤害和闭经的评估在饮食失调的早期诊断和治疗中是至关重要的,特别是在有限制性饮食行为的患者中。
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引用次数: 0
Depressive symptoms as a moderator of fat talk and body image outcomes within mother-daughter dyads 抑郁症状对母女二代肥胖谈话和身体形象结果的调节作用。
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-09 DOI: 10.1016/j.eatbeh.2025.102040
Madison Hannapel , Jamie M. Lawler , Eamonn Arble , Chong Man Chow

Objective

Adolescent girls and mothers are vulnerable to poor body image outcomes, which are often reinforced through fat talk, a self-disparaging body-related conversation. Depression may exacerbate this risk, particularly among those engaging in fat talk. This study examined the associations, among mother-daughter dyads, between fat talk and restrictive, emotional, and external disordered eating, eating disorder symptoms, and body dissatisfaction, as well as whether depression moderated these associations.

Method

104 mother-daughter dyads completed online measures. Adolescent daughters (M = 15.73 years old; SD = 2.51) and their mothers (M = 43.17 years old; SD = 8.58) were primarily white/Caucasian.

Results

Actor effects of fat talk significantly predicted all body image outcomes. Partner effects emerged only for daughters' fat talk predicting mothers' body dissatisfaction. Depression moderated the association between fat talk and restrictive eating but did not moderate other associations. However, depression did independently predict poorer body image outcomes.

Discussion

Findings highlight the importance of studying mother-daughter dyads and capturing how psychopathology contributes to subclinical eating disordered behaviors, informing risk identification for eating disorder development.
目的:青春期的女孩和母亲很容易受到身体形象不佳的影响,而这种不佳往往会通过“肥胖谈话”(一种自我贬低的与身体有关的谈话)得到强化。抑郁症可能会加剧这种风险,尤其是那些喜欢闲聊的人。本研究调查了母女二人组中肥胖谈话与限制性、情绪性和外在饮食失调、饮食失调症状和身体不满意之间的联系,以及抑郁是否会缓和这些联系。方法:104对母女在线完成问卷调查。青春期女儿(M = 15.73岁,SD = 2.51)及其母亲(M = 43.17岁,SD = 8.58)主要为白人/高加索人。结果:肥胖谈话的演员效应显著预测所有身体形象结果。伴侣效应只出现在女儿的肥胖谈话中,预示着母亲对身体的不满。抑郁缓和了肥胖谈话和限制性饮食之间的联系,但没有缓和其他联系。然而,抑郁确实独立预示着较差的身体形象结果。讨论:研究结果强调了研究母女二人的重要性,并捕捉精神病理学对亚临床饮食失调行为的影响,为饮食失调发展的风险识别提供信息。
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引用次数: 0
Examining associations among food insecurity, muscularity-oriented disordered eating, and internalizing symptoms in undergraduate students 研究大学生食物不安全、肌肉导向饮食失调和内化症状之间的关系。
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-09 DOI: 10.1016/j.eatbeh.2025.102041
Aditya Thakur , Lisa Y. Zhu , Lindsay P. Bodell
Food insecurity (FI) is a serious public health concern linked to negative physical and mental outcomes, including eating disorder symptoms. However, little is known about its relationship with muscularity-oriented disordered eating (MODE), which involves eating behaviours aimed at increasing muscle mass and decreasing body fat. This study examined the association between FI and MODE, as well as the potential indirect effects of depression and anxiety. A sample of 394 undergraduate students (72.34 % women) from a Canadian university completed online self-report measures of FI, MODE, depression, and anxiety. Linear regression analyses indicated that FI was significantly positively associated with MODE, even when controlling for gender. Indirect effects analyses further revealed that this association was partially explained by depression and anxiety in women, suggesting that psychological distress may play a key role in linking FI to MODE. Importantly, our findings provide evidence that MODE is not limited to individuals with greater financial resources to access high-protein diets and supplements. Food insecurity does not preclude engagement in MODE, emphasizing the need for theoretical models and interventions that consider FI as a potential risk factor. Future research should employ longitudinal designs to clarify the temporal relationship between FI, MODE, and mental health factors, as well as explore these associations in more diverse populations.
粮食不安全是一个严重的公共卫生问题,与负面的身心后果(包括饮食失调症状)有关。然而,它与以肌肉为导向的饮食失调(MODE)的关系知之甚少,MODE涉及旨在增加肌肉质量和减少体脂的饮食行为。本研究探讨了FI和MODE之间的关系,以及抑郁和焦虑的潜在间接影响。来自加拿大一所大学的394名本科生(72.34%为女性)完成了FI、MODE、抑郁和焦虑的在线自我报告测量。线性回归分析表明,即使在控制性别的情况下,FI也与MODE显著正相关。间接效应分析进一步揭示,女性的抑郁和焦虑可以部分解释这种关联,这表明心理困扰可能在FI与MODE之间起关键作用。重要的是,我们的研究结果提供的证据表明,MODE并不局限于有更多经济资源获得高蛋白饮食和补充剂的个人。粮食不安全并不排除参与模式,强调需要将FI视为潜在风险因素的理论模型和干预措施。未来的研究应该采用纵向设计来阐明FI、MODE和心理健康因素之间的时间关系,并在更多样化的人群中探索这些关联。
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引用次数: 0
Dietary restraint and emotional eating mediate the relationship between negative body image and diet quality in U.S. Army Soldiers 美国陆军士兵负面身体形象与饮食质量之间的关系由饮食限制和情绪性进食介导。
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-29 DOI: 10.1016/j.eatbeh.2025.102039
Bridget A. Owens , Julianna M. Jayne , Renee E. Cole , J. Philip Karl
Body composition requirements for U.S. Army Soldiers may increase risk of negative body image and unhealthy dietary behaviors, which may in turn lead to poor nutrition. This study aimed to determine whether negative body image was associated with worse diet quality in U.S. Army Soldiers and whether dietary restraint and emotional eating served as mediators. A cross-sectional study of U.S. Army Soldiers who completed the Military Eating Behavior Survey was conducted (N = 427, 93 % male, 23 ± 5 years of age). Diet quality was calculated using the Healthy Eating Index 2015 (HEI-2015) to assess total HEI, adequacy, and moderation components. Linear regression models were used to examine associations between body image, dietary restraint, emotional eating, and diet quality. Mediation models were tested to measure the indirect effect of dietary restraint and emotional eating on the association between body image and diet quality. Results demonstrated that higher concern with body image was associated with higher dietary restraint (B = 0.12, p < .0001) and higher emotional eating (B = 0.07, p = .0001). Dietary restraint was positively associated with Total HEI-2015 score (B = 1.10, p < .0001) and HEI-2015 moderation (B = 0.32, p < .0001) and adequacy (B = 0.78, p < .0001) scores. In mediation analyses, there was a significant indirect effect of body image on diet quality through restraint (a:0.25, b:0.41, c’:-0.12, ab:0.10; 95 % bootstrap CI: 0.06, 0.15) and emotional eating (a:0.18, b:-0.15, c’:0.05, ab:-0.04; 95 % bootstrap CI: −0.07, −0.01). Findings suggest that dietary restraint and emotional eating may be differentially associated with body image and diet quality. Whether these relationships persist over time is unclear.
美国陆军士兵的身体成分要求可能会增加负面身体形象和不健康饮食行为的风险,这可能反过来导致营养不良。本研究旨在确定美国陆军士兵的负面身体形象是否与较差的饮食质量有关,以及饮食限制和情绪化饮食是否起到中介作用。本研究对完成军队饮食行为调查的美国陆军士兵进行了横断面研究(N = 427, 93%为男性,23±5岁)。使用健康饮食指数2015 (HEI-2015)计算饮食质量,以评估总HEI、充足性和适度成分。线性回归模型用于检验身体形象、饮食限制、情绪性进食和饮食质量之间的关系。通过中介模型检验饮食约束和情绪性饮食对身体形象与饮食质量关系的间接影响。结果表明,对身体形象的高度关注与较高的饮食限制相关(B = 0.12, p
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引用次数: 0
Food addiction and personality traits: A three-levels meta-analysis of correlational studies 食物成瘾与人格特质:相关研究的三水平元分析。
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-18 DOI: 10.1016/j.eatbeh.2025.102038
G. Rogier , C. Ameglio , G. Penco , C.S. Pace , S. Muzi , A. Cornil , P. Velotti

Background

Epidemiological and clinical studies highlighted that food addiction is a clinically relevant phenomenon. A large number of studies investigated its link with personality traits. However, a systematic overview and a meta-analysis of these results is lacking.

Methods

We systematically searched for studies investigating the link between food addiction and personality traits on several academic databases. For each personality trait, we performed a three-level meta-analysis estimating the strength of its association with food addiction severity. The role of moderators was tested employing meta-regression.

Results

The screening process led to the selection of 37 studies. Most contributions investigate impulsivity or the Cloninger's dimensions with the Impulsive Behavior Scale or the Temperament and Character Inventory respectively. An insufficient number of observations were retrieved to evaluate the association between food addiction severity and some personality traits such as those measured by the five-factor model. The highest effect sizes observed linked food addiction to low levels of self-directedness (r = −0.26), to high levels of both negative (r = 0.33) and positive (r = 0.27) urgency and to attentional impulsiveness (r = 0.31). Age and gender significantly moderated some of the effect sizes.

Conclusions

More research is needed to increase our knowledge regarding the association between food addiction severity and some personality traits. Results suggested that food addiction may be associated to the same personality traits that characterized addictions and eating disorders (e.g. harm avoidance and impulsivity), also revealing its specificity (i.e. the lack of significant association with reward dependence).
背景:流行病学和临床研究表明,食物成瘾是一种与临床相关的现象。大量的研究调查了它与人格特质的关系。然而,缺乏对这些结果的系统概述和荟萃分析。方法:我们系统地检索了几个学术数据库中关于食物成瘾与人格特质之间关系的研究。对于每个人格特质,我们进行了一个三水平的荟萃分析,估计其与食物成瘾严重程度的关联强度。采用元回归对调节因子的作用进行检验。结果:筛选过程最终筛选出37项研究。大多数研究分别用冲动行为量表或气质和性格量表来考察冲动性或Cloninger维度。没有足够的观察结果来评估食物成瘾严重程度和一些人格特征之间的关系,比如那些由五因素模型测量的人格特征。观察到的最高效应大小将食物成瘾与低水平的自我指导(r = -0.26),高水平的负(r = 0.33)和正(r = 0.27)紧迫性以及注意冲动(r = 0.31)联系起来。年龄和性别显著地调节了一些效应量。结论:需要更多的研究来增加我们对食物成瘾严重程度和某些人格特征之间关系的了解。结果表明,食物成瘾可能与成瘾和饮食失调的人格特征(如伤害回避和冲动)有关,也揭示了其特异性(即与奖励依赖缺乏显著关联)。
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引用次数: 0
An exploration of generational status and enculturation as putative protective factors for disordered eating behaviors and cognitions among college students 代际地位和文化作为大学生饮食失调行为和认知的保护性因素的探讨。
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-16 DOI: 10.1016/j.eatbeh.2025.102036
Julia Yermash , Tatyana Bidopia , Yvette Karvay , Haruka Minami , Shane W. Kraus , Natasha L. Burke
Youth from immigrant families navigate multiple cultures concurrently, and culture largely influences how disordered eating behaviors and cognitions (DEBC) present. Enculturation (i.e., maintaining one's heritage traditions, values, beliefs, etc. while living within the dominant culture) may – in contrast to acculturation – function as a protective factor against DEBC and body-image issues. Considering eating disorders' deleterious outcomes, understanding whether enculturation can be leveraged to protect against DEBC is important; however, there is a dearth of research in this area. To address this gap, associations among generational status, enculturation, and DEBC (assessed by the Eating Pathology Symptoms Inventory (EPSI)) were investigated in 467 college students using analysis of covariance and multiple linear regression models. Enculturation and generational status were associated as hypothesized, but positively, which was contrary to hypotheses. Generational status and enculturation did not individually influence DEBC, but generational status moderated the relationship between enculturation and Negative Attitudes toward Obesity, an EPSI subscale. Among the first-generation group, enculturation was positively associated with Negative Attitudes toward Obesity while for the third- and fourth-generation groups, enculturation was negatively associated with Negative Attitudes toward Obesity. The association between generational status, enculturation, and DEBC is nuanced and complex, but certain aspects of DEBC may be particularly important factors for first-generation individuals. Future research should investigate these relationships within specific cultural, racial, and ethnic groups and among non-college populations.
来自移民家庭的年轻人同时适应多种文化,文化在很大程度上影响了饮食失调行为和认知(DEBC)的表现。与文化适应相反,文化适应(即生活在主流文化中保持自己的遗产传统、价值观、信仰等)可能是防止DEBC和身体形象问题的保护因素。考虑到饮食失调的有害后果,了解是否可以利用文化适应来预防DEBC是很重要的;然而,这方面的研究还很缺乏。为了解决这一差距,采用协方差分析和多元线性回归模型对467名大学生进行了代际地位、文化适应和DEBC之间的关系(由进食病理症状量表(EPSI)评估)的调查。文化和代际地位的关联是假设的,但是积极的,这与假设相反。代际地位和文化不单独影响DEBC,但代际地位调节了文化与消极肥胖态度(EPSI子量表)之间的关系。在第一代群体中,文化适应与消极肥胖态度呈正相关,而在第三代和第四代群体中,文化适应与消极肥胖态度呈正相关。代际地位、文化和DEBC之间的联系是微妙而复杂的,但DEBC的某些方面可能对第一代个体特别重要。未来的研究应该在特定的文化、种族和民族群体以及非大学人口中调查这些关系。
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引用次数: 0
Validation of the Eating Disorders-15 (ED-15) in Mexican patients across levels of care: Psychometric properties in a clinical sample 跨护理水平的墨西哥患者饮食失调-15 (ED-15)的验证:临床样本的心理测量特性
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-16 DOI: 10.1016/j.eatbeh.2025.102037
Eva Trujillo-ChiVacuán , Emilio J. Compte , Glenn Waller

Objective

This study aimed to validate the Eating Disorders-15 (ED-15) in a clinically diverse sample of Mexican patients with eating disorders (EDs). Given the increasing prevalence of EDs in Latin America and the need for validated assessment tools, this study evaluated the psychometric properties of the ED-15 in this specific cultural and clinical context.

Method

A total of 286 individuals diagnosed with EDs were recruited from a specialized treatment center in Mexico. Participants completed the ED-15, alongside the Eating Disorder Examination-Questionnaire 7, the Body Shape Questionnaire-8, the Body Appreciation Scale-2, the Patient Health Questionnaire-9, and the Clinical Impairment Assessment. Confirmatory factor analyses tested four models, including the original two-factor model, a higher-order model, and a bi-factor model. Internal consistency, as well as convergent validity, were assessed.

Results

The original two-factor model showed excellent fit and was retained as the final solution based on model parsimony, goodness-of-fit indices, and theoretical considerations. The ED-15 demonstrated high internal consistency (ω > 0.80), strong positive associations with ED psychopathology, body dissatisfaction, depressive symptoms, and clinical impairment, and strong negative associations with body appreciation.

Discussion

These findings support the reliability and validity of the ED-15 in a Mexican clinical sample. The study provides robust psychometric evidence for the use of the ED-15 in clinical and research settings in Latin America and highlights the importance of culturally validated brief instruments for assessing eating disorder symptoms.
目的:本研究旨在验证饮食失调-15 (ED-15)在墨西哥饮食失调(ed)患者临床多样化样本中的有效性。鉴于ed在拉丁美洲日益流行,以及对有效评估工具的需求,本研究评估了ED-15在这一特定文化和临床背景下的心理测量特性。方法从墨西哥的一个专门治疗中心招募286名诊断为ed的个体。参与者完成了ED-15、饮食失调检查问卷7、体型问卷8、身体欣赏量表2、患者健康问卷9和临床损害评估。验证性因子分析测试了四种模型,包括原始的双因素模型、高阶模型和双因素模型。内部一致性,以及收敛效度进行了评估。结果基于模型简约性、拟合优度指标和理论考虑,保留原双因素模型为最终解。ED-15表现出较高的内部一致性(ω > 0.80),与ED精神病理、身体不满、抑郁症状和临床损害呈强正相关,与身体欣赏呈强负相关。这些发现支持ED-15在墨西哥临床样本中的可靠性和有效性。该研究为ED-15在拉丁美洲临床和研究环境中的使用提供了强有力的心理测量证据,并强调了文化验证的简短工具对评估饮食失调症状的重要性。
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引用次数: 0
Medications as precipitating factors for potential eating disorders: A disproportionality analysis using FDA adverse event reports 药物作为潜在饮食失调的诱发因素:使用FDA不良事件报告的不相称性分析。
IF 2.6 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-13 DOI: 10.1016/j.eatbeh.2025.102034
Liyun Zheng , Shuang Zhang

Objective

Compared to psychosocial factors, medications remain less well recognized as precipitating factors for eating disorders. This study aims to identify medications potentially associated with eating disorders using the U.S. Food and Drug Administration's Adverse Event Reporting System (FAERS) database.

Methods

FAERS reports related to potential eating disorders from January 2004 to December 2024 were retrieved. Reporting odds ratios (RORs) were calculated to detect disproportionate signals, with Fisher's exact test and Bonferroni correction applied for adjustments in multiple comparisons. Drugs exhibiting significant positive signals (ROR 95 % confidence interval lower bound >1, adjusted p-value < 0.01) with over 100 reports were selected for LASSO regression analysis. Logistic regression, adjusted for age, sex, and reporter type, was employed to identify precipitating drugs.

Results

Among 20,145 reports, 62.7 % involved females, with a median age of 59 years (interquartile range: 42–71). Thirty drugs showed significant positive signals. Nine potential precipitating medications were identified through LASSO and logistic regression, including octreotide, ribociclib, sunitinib, rivastigmine, everolimus, quetiapine, palbociclib, esomeprazole, and pregabalin.

Conclusion

This study identifies certain medications that may act as precipitating factors for potential eating disorders, particularly in middle-aged and older populations. Clinicians should monitor these medications that affect appetite, weight, or carry abuse potential to prevent harm, especially in patients with eating disorders or at-risk populations.
目的:与心理社会因素相比,药物作为饮食失调的诱发因素仍未得到充分认识。本研究旨在利用美国食品和药物管理局的不良事件报告系统(FAERS)数据库确定可能与饮食失调有关的药物。方法:检索2004年1月至2024年12月与潜在饮食失调相关的FAERS报告。计算报告优势比(RORs)来检测不成比例的信号,使用Fisher精确检验和Bonferroni校正来进行多重比较的调整。显示显著阳性信号的药物(ROR 95%置信区间下限bbb1,调整p值)结果:在20145份报告中,62.7%涉及女性,中位年龄为59岁(四分位数范围:42-71岁)。30种药物显示出明显的阳性信号。通过LASSO和logistic回归确定了9种潜在的沉淀药物,包括奥曲肽、核波西尼、舒尼替尼、利瓦斯汀、依维莫司、喹硫平、帕博西尼、埃索美拉唑和普瑞巴林。结论:这项研究确定了某些药物可能是潜在饮食失调的诱发因素,特别是在中年和老年人中。临床医生应该监测这些影响食欲、体重或有滥用可能的药物,以防止伤害,特别是在饮食失调患者或高危人群中。
{"title":"Medications as precipitating factors for potential eating disorders: A disproportionality analysis using FDA adverse event reports","authors":"Liyun Zheng ,&nbsp;Shuang Zhang","doi":"10.1016/j.eatbeh.2025.102034","DOIUrl":"10.1016/j.eatbeh.2025.102034","url":null,"abstract":"<div><h3>Objective</h3><div>Compared to psychosocial factors, medications remain less well recognized as precipitating factors for eating disorders. This study aims to identify medications potentially associated with eating disorders using the U.S. Food and Drug Administration's Adverse Event Reporting System (FAERS) database.</div></div><div><h3>Methods</h3><div>FAERS reports related to potential eating disorders from January 2004 to December 2024 were retrieved. Reporting odds ratios (RORs) were calculated to detect disproportionate signals, with Fisher's exact test and Bonferroni correction applied for adjustments in multiple comparisons. Drugs exhibiting significant positive signals (ROR 95 % confidence interval lower bound &gt;1, adjusted <em>p</em>-value &lt; 0.01) with over 100 reports were selected for LASSO regression analysis. Logistic regression, adjusted for age, sex, and reporter type, was employed to identify precipitating drugs.</div></div><div><h3>Results</h3><div>Among 20,145 reports, 62.7 % involved females, with a median age of 59 years (interquartile range: 42–71). Thirty drugs showed significant positive signals. Nine potential precipitating medications were identified through LASSO and logistic regression, including octreotide, ribociclib, sunitinib, rivastigmine, everolimus, quetiapine, palbociclib, esomeprazole, and pregabalin.</div></div><div><h3>Conclusion</h3><div>This study identifies certain medications that may act as precipitating factors for potential eating disorders, particularly in middle-aged and older populations. Clinicians should monitor these medications that affect appetite, weight, or carry abuse potential to prevent harm, especially in patients with eating disorders or at-risk populations.</div></div>","PeriodicalId":11476,"journal":{"name":"Eating behaviors","volume":"59 ","pages":"Article 102034"},"PeriodicalIF":2.6,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Eating behaviors
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