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Clinical performance of fiber reinforced FRC base and bonded CAD/CAM resin composite endocrowns versus conventional lithium disilicate endocrowns in posterior teeth (Randomized Clinical Trial) 后牙纤维增强 FRC 基底和粘接 CAD/CAM 树脂复合内冠与传统二硅酸锂内冠的临床表现(随机临床试验)
Pub Date : 2024-07-01 DOI: 10.21608/edj.2024.291295.3046
S. kandil, Sameh Abou-Steit, Nancy Helmy Mickael
Purpose: To evaluate clinical performance of fiber reinforced composite base and bonded CAD/CAM resin composite endocrowns compared to lithium disilicate endocrowns over one year. Methods: A total of 110 endocrowns, 55 lithium disilicate endocrowns (group I) (IPS e. max CAD) and 55 of bonded CAD/CAM resin composite endocrowns with fiber reinforced FRC base (group II) (Grandio) were used to restore endodontically treated molars. First shade selection was performed followed by cavity preparation and digital impression. Then restorations were designed, milled and checked intraorally before cementation using resin cement. The restorations were evaluated at baseline, 6 and 12 months using Modified USPHS criteria. Statistical analysis was performed with SPSS 20®, Graph Pad Prism® and Microsoft Excel 2016. Results: Regarding fracture and marginal adaptation, all restorations in both groups had Alpha score (100%); at base line, after 6, and 12 months. Regarding retention, all restorations in both groups had Alpha score (100%); at base line, and after 6 months. While after 12 months, only one case had Charlie score in group I with insignificant difference between groups as P=0.32. Regarding shade match, all restorations in both groups had Alpha score (100%); at base line while after 6 months two cases were Bravo in group II with insignificant difference between groups as P=0.14. While after 12 months, three cases were Bravo in group II with insignificant difference between groups as P=0.07. Conclusion: CAD/CAM resin composite endocrowns with fiber reinforced FRC base are just as dependable as lithium disilicate for restoring non-vital posterior teeth.
目的:评估纤维增强复合材料基底和粘接CAD/CAM树脂复合材料内冠与二硅酸锂内冠一年来的临床表现比较。方法:共使用 110 个内冠:共使用了 110 个内冠,其中 55 个二硅酸锂内冠(I 组)(IPS e. max CAD)和 55 个带纤维增强 FRC 基底的粘结 CAD/CAM 树脂复合材料内冠(II 组)(Grandio)用于修复牙髓治疗过的磨牙。首先进行色调选择,然后进行牙洞预备和数字印模。然后设计、研磨修复体,并在使用树脂水门汀粘接前进行口内检查。修复体在基线期、6 个月和 12 个月时按照修改后的 USPHS 标准进行评估。使用 SPSS 20®、Graph Pad Prism® 和 Microsoft Excel 2016 进行统计分析。结果:在断裂和边缘适应方面,两组的所有修复体在基线、6 个月后和 12 个月后都获得了 Alpha 分数(100%)。在固位方面,两组的所有修复体在基线和 6 个月后的 Alpha 得分均为(100%)。而在 12 个月后,I 组中只有一个病例获得了 Charlie 分,组间差异不显著(P=0.32)。在色调匹配方面,两组的所有修复体在基线时都获得了 Alpha 评分(100%),而在 6 个月后,第二组有两个病例获得了 Bravo 评分,组间差异不显著(P=0.14)。12 个月后,第二组有三个病例达到 Bravo 水平,组间差异不显著(P=0.07)。结论带有纤维增强 FRC 基底的 CAD/CAM 树脂复合内冠与二硅酸锂修复非重要后牙一样可靠。
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引用次数: 0
One Year Clinical Follow-up of the rebound of bleached teeth Color using of two different in-office bleaching techniques. 使用两种不同的诊所漂白技术对漂白牙齿颜色的反弹进行为期一年的临床跟踪。
Pub Date : 2024-07-01 DOI: 10.21608/edj.2024.280972.2995
E. M. El.Sayed, A. Nassar
Aim: A clinical study to assess the rebound of the color of bleached teeth for one year follow up. Materials and methods: Thirty non-smoker patients (18-23years) having anterior upper and lower segments from canine to canine with an average shade of A4 were selected. Teeth were checked to be free of caries, restorations, hypoplastic lesions, stains, and cracks. The shades were measured mainly by using Vita classic visual standardized shade guide and confirmed by spectrophotometer (easy shade) only in case of any confliction in the scores of both evaluators. Cooperative patients ready for follow up were involved in the present study. Segments were equally and unsystematically distributed into 2 groups (30 segments each) according to the bleaching system used, Group I: Chemical activated bleaching system 40% HP (White Smile power whitening YF) & Group II: light activated bleaching system, mixed 32% HP (White smile light whitening AC). Each group involved 15 upper and 15 lower segments at the 30 pts. Every group was distributed into 2 subgroups according to the location whether upper or lower segments. The manufacturer’s instructions were followed and applied in every bleaching process. Every tooth shade was documented before bleaching, 24 hours after
目的:一项临床研究,评估漂白后牙齿颜色在一年随访期间的反弹情况。材料与方法选取 30 名非吸烟患者(18-23 岁),他们的上下前牙从犬齿到犬齿,平均色泽为 A4。检查牙齿是否有龋齿、修复体、发育不全的病变、污渍和裂缝。色调主要通过 Vita classic 视觉标准色调指南进行测量,只有在两位评估者的评分发生冲突时,才会通过分光光度计(易色调)进行确认。准备接受随访的合作患者参与了本研究。根据所使用的漂白系统,患者被平均无序地分为两组(每组 30 例):第一组:化学激活漂白系统,40% HP(White Smile 强力美白 YF);第二组:光激活漂白系统,混合 32% HP(White Smile 光美白 AC)。每组包括 15 个上段和 15 个下段,共 30 个点。每组根据上段或下段的位置分为两个亚组。每个漂白过程都遵循并应用了制造商的说明。在漂白前、漂白后 24 小时、漂白后 24 小时、漂白后 24 小时和漂白后 24 小时,记录每颗牙齿的色泽。
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引用次数: 0
Effect of Two Techniques of Separated File Removal Systems on Dentin Loss and Fracture Resistance of Teeth (In Vitro Study) 两种分离式锉磨系统技术对牙本质损失和牙齿抗折性的影响(体外研究)
Pub Date : 2024-07-01 DOI: 10.21608/edj.2024.283058.3011
F. Barakat, M. Attia
Purpose: to evaluate the fracture resistance of teeth after removal of separated files using either the BTR Pen system or Zumax kit, the impact of the retrieval technique on the fracture resistance, and to assess the correlation between the amount of volume lost during retrieval and fracture resistance of teeth. Materials and Methods: sixty mandibular first molar teeth were selected. Teeth were placed in acrylic resin blocks and were randomly assigned into two groups. Group A: the control group (n=20) and Group B: the study group (n=40). In the study group, five mm of ProTaper Next X2 rotary files were separated in the mesiobuccal canals. The study group was divided into two subgroups, 20 each. Group BI: the broken tool remover (BTR) pen system was utilized to retrieve separated instruments and Group BII: the Zumax kit was employed for retrieval of separated instruments. Cone Beam Computed Tomography (CBCT) was taken before and after retrieval for volumetric analysis. Fracture loading test was performed using the universal testing machine. Values were analyzed by SPSS software using F-test (ANOVA) and independent t-test. Results: there was a significant increase (P=0.001) in canal volume in the study groups. Comparing the mean fracture resistance of the three groups, no significant difference among the groups was found (P= 0.384). Conclusions: retrieving separated instruments from the coronal third of the root canal is regarded as a safe procedure and has no impact on tooth fracture resistance.
目的:评估使用 BTR Pen 系统或 Zumax 套件拔除分离锉后牙齿的抗折性、取锉技术对抗折性的影响,以及评估取锉过程中损失的体积与牙齿抗折性之间的相关性。材料和方法:选取六十颗下颌第一磨牙。将牙齿置于丙烯酸树脂块中,随机分为两组。A 组:对照组(20 个);B 组:研究组(40 个)。在研究组中,在中颊面管中分离出 5 毫米的 ProTaper Next X2 旋转锉。研究组分为两个亚组,每组 20 人。BI 组:使用破损工具取出器(BTR)笔系统取出分离的器械;BII 组:使用 Zumax 套件取出分离的器械。在取回器械前后均拍摄了锥形束计算机断层扫描(CBCT),以进行体积分析。使用万能试验机进行骨折加载测试。使用 SPSS 软件进行 F 检验(方差分析)和独立 t 检验分析数值。结果:研究组的牙槽骨体积明显增加(P=0.001)。比较三组的平均折断阻力,各组间无明显差异(P= 0.384)。结论:从根管的冠状三分之一处取回分离的器械被认为是一种安全的程序,对牙齿的抗折性没有影响。
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引用次数: 0
Evaluation of Biting Force between Conventional and 3D Printed Dentures ( A Crossover study) 传统义齿与 3D 打印义齿咬合力的评估(交叉研究)
Pub Date : 2024-07-01 DOI: 10.21608/edj.2024.277296.2982
Mohamed Hakim
Aim of study : To evaluate and compare biting force (BF) and biting force changes between conventional complete (CD) dentures and 3D printed dentures. Materials & Methods : 14 completely edentulous patients were selected from the out-patient clinic, Removable Prosthodontic Department, Beni-Suef University with age range 45–55 years with a good general and oral health. Each patient received two set of dentures, CDs and 3D printed dentures. They were asked to wear and use each denture set for 3 months but with a 2-week wash out period between them. The sequence of the dentures was randomly assigned for each patient. BF was measured with an occlusal force meter three times (at baseline, after 1 month, and after 3 months) at the 1st molar area bilaterally. The mean of the records were considered to be the patient’s maximum biting force. Results : There was a statistically significant increase in the mean values of BF in the two studied groups with insignificant difference between mean values of BF between the right & left sides and BF mean values were significantly higher with the 3D printed dentures than with the conventional complete dentures. Conclusion : Within the limitations of this study, it may be concluded that biting force increases by time in complete denture wearers. 3D printed dentures may provide better biting force than conventionally constructed dentures.
研究目的:评估和比较传统全口义齿(CD)和三维打印义齿的咬合力(BF)和咬合力变化。材料和方法:研究人员从贝尼苏伊夫大学可摘义齿修复科门诊部挑选了 14 名全身和口腔健康状况良好、年龄在 45-55 岁之间的全口无牙患者。每位患者都收到了两套假牙,分别是 CD 假牙和 3D 打印假牙。他们被要求佩戴和使用每套假牙 3 个月,但中间有 2 周的清洗期。每位患者的假牙顺序都是随机分配的。在双侧第 1 磨牙区用咬合力计测量 BF 三次(基线、1 个月后和 3 个月后)。记录的平均值被视为患者的最大咬合力。结果:两组患者的咬合力平均值均有显著增加,但左右两侧的咬合力平均值差异不明显,3D 打印假牙的咬合力平均值明显高于传统全口义齿。结论:在本研究的限制条件下,可以得出结论:全口义齿佩戴者的咬合力会随着时间的推移而增加。与传统假牙相比,三维打印假牙可提供更好的咬合力。
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引用次数: 0
Effectiveness of natural remineralizing agents on microhardness of white spot lesions: In vitro study 天然再矿化剂对白斑病变微硬度的影响:体外研究
Pub Date : 2024-07-01 DOI: 10.21608/edj.2024.286885.3027
Ehsan Hossam Eldin Aly, Yousra mohamed Abdelrahem, M. Eliwa
Purpose: This in vitro study is conducted to compare the effect of extracts of Ginger and Rosemary on the microhardness of white spot lesions to sodium fluoride varnish. Materials and methods: The current study used thirty extracted incisors. Ten teeth(n = 10) in each group had a remineralizing treatment: group 1:rosemary, group 2: ginger, and group 3: sodium fluoride varnish. A nail polish was applied on labial surfaces except to a window of 4x4mm and the microhardness test was done. Then all samples were immersed in demineralizing solution for four days to produce white spot lesions. Then testing microhardness was conducted. The remineralizing agents were applied to each group for ten days. The samples were immersed in artificial saliva between treatments. Lastly, microhardness test was conducted. Results: ANOVA test was used to Compare between groups. Comparison within the same group was performed using a paired t-test. The Fluoride group was not significantly different than the other 2 groups after remineralization, The mean value was 63.04±3.79 in the fluoride group, in comparison to 64.01±3.85 in the Ginger group and 62.20±3.91 in the Rosemary group. The mean value recorded in the rosemary group was significantly higher than ginger group (p=0.047). Considering the percent of change from Demineralization to remineralization the highest mean value of percentage increase occurred in the ginger group (34.50±18; median 30.98), succeeded by fluoride (30.49±15.54; median 32.53). Conclusions: Rosemary, ginger, and fluoride varnish reduce white spot lesions and are more favorable for prevention and remineralization of early enamel lesions.
目的:本体外研究旨在比较生姜和迷迭香提取物对氟化钠漆膜白斑病变微硬度的影响。材料和方法:本研究使用了 30 颗拔出的门牙。每组 10 颗牙齿(n = 10)进行再矿化处理:第 1 组:迷迭香,第 2 组:生姜,第 3 组:氟化钠清漆。在唇面涂上指甲油,但不超过 4x4mm 的窗口,然后进行显微硬度测试。然后将所有样本浸泡在脱矿物质溶液中四天,以产生白斑病变。然后进行显微硬度测试。每组样品均使用再矿化剂十天。在两次处理之间,将样品浸泡在人工唾液中。最后进行显微硬度测试。结果组间比较采用方差分析。同组内的比较采用配对 t 检验。氟化物组的平均值为 63.04±3.79,而生姜组为 64.01±3.85,迷迭香组为 62.20±3.91。迷迭香组的平均值明显高于生姜组(P=0.047)。考虑到从脱矿化到再矿化的百分比变化,生姜组的百分比增加平均值最高(34.50±18;中位数为 30.98),其次是氟化物组(30.49±15.54;中位数为 32.53)。结论迷迭香、生姜和氟化物涂膜可减少白斑病变,更有利于早期釉质病变的预防和再矿化。
{"title":"Effectiveness of natural remineralizing agents on microhardness of white spot lesions: In vitro study","authors":"Ehsan Hossam Eldin Aly, Yousra mohamed Abdelrahem, M. Eliwa","doi":"10.21608/edj.2024.286885.3027","DOIUrl":"https://doi.org/10.21608/edj.2024.286885.3027","url":null,"abstract":"Purpose: This in vitro study is conducted to compare the effect of extracts of Ginger and Rosemary on the microhardness of white spot lesions to sodium fluoride varnish. Materials and methods: The current study used thirty extracted incisors. Ten teeth(n = 10) in each group had a remineralizing treatment: group 1:rosemary, group 2: ginger, and group 3: sodium fluoride varnish. A nail polish was applied on labial surfaces except to a window of 4x4mm and the microhardness test was done. Then all samples were immersed in demineralizing solution for four days to produce white spot lesions. Then testing microhardness was conducted. The remineralizing agents were applied to each group for ten days. The samples were immersed in artificial saliva between treatments. Lastly, microhardness test was conducted. Results: ANOVA test was used to Compare between groups. Comparison within the same group was performed using a paired t-test. The Fluoride group was not significantly different than the other 2 groups after remineralization, The mean value was 63.04±3.79 in the fluoride group, in comparison to 64.01±3.85 in the Ginger group and 62.20±3.91 in the Rosemary group. The mean value recorded in the rosemary group was significantly higher than ginger group (p=0.047). Considering the percent of change from Demineralization to remineralization the highest mean value of percentage increase occurred in the ginger group (34.50±18; median 30.98), succeeded by fluoride (30.49±15.54; median 32.53). Conclusions: Rosemary, ginger, and fluoride varnish reduce white spot lesions and are more favorable for prevention and remineralization of early enamel lesions.","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141711607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Two Intracanal Irrigation Solutions Delivered Through Cryotherapy on Post-Endodontic Pain Relieve. A Randomized Clinical Trial 通过冷冻疗法提供的两种根管内冲洗溶液对缓解根管治疗后疼痛的效果。随机临床试验
Pub Date : 2024-07-01 DOI: 10.21608/edj.2024.290051.3040
Manal Abdelbaky, mostafa shaker
Aim: The present randomized clinical trial was designed to investigate the effect of cryotherapy (cryo) utilizing chlorhexidine (CHX) as compared to saline (NS) on pain reduction after single visit endodontic treatment. Methodology: Selected patients were seeking emergency treatment of painful symptomatic irreversible pulpitis with symptomatic apical periodontitis for single rooted teeth. Sixty-eight male patients, 25 to 50 years old were distributed randomly in 4 groups of 17 each according to the final irrigation protocol: control (GI): NS at room temperature, control (GII): CHX at room temperature, intervention (GIII): cryo with NS (cryo/NS), , and intervention (G IV): (cryo / CHX) before final obturation in the same visit. Patients were trained and asked to report pain incidence and level after12, 24, 48, 72 hours and at 7 days as well as frequency of analgesic intake. Kruskal Wallis, followed by Dunn`s multiple comparisons test were used for comparison between the 4 groups, while Chi square test was used for qualitative data. The significance level was set at p ≤0.05. Results: G III: (cryo/NS) and G IV: cryo/CHX showed significantly highest pain reduction after 24, 48, and 72 hours P= 0.000 I. Significantly more prolonged pain reduction curve was found in GI: cryo/NS. Pain in both tested groups declined to no pain after 7 days. Frequency of analgesic need was insignificant for the two groups P=0.27. Conclusions: From the results of the present study it appeared clearly that cryo helped in pain reduction whether used with CHX or NS. CHX used as a cryo material showed insignificant trend toward effective time dependent pain reduction as compared to NS. This might be because of its substantivity. Further study is needed to better clarifying this point.
目的:本随机临床试验旨在研究使用洗必泰(CHX)的冷冻疗法(cryo)与生理盐水(NS)相比,对单次牙髓治疗后减轻疼痛的效果。研究方法:所选患者均为寻求紧急治疗的单根牙齿疼痛症状性不可逆牙髓炎和症状性根尖牙周炎患者。68名年龄在25至50岁之间的男性患者被随机分为4组,每组17人,按照最终的灌洗方案:对照组(GI):对照组(GI):室温下的 NS;对照组(GII):室温下的 CHX;干预组(GI):室温下的 NS:干预组(GIII):低温与 NS(低温/NS);干预组(G IV):(低温/CHX)。对患者进行了培训,并要求他们报告 12、24、48、72 小时后和 7 天后的疼痛发生率和疼痛程度,以及服用镇痛药的频率。四组之间的比较采用 Kruskal Wallis 检验和 Dunn`s 多重比较检验,定性数据则采用卡方检验。显著性水平设定为 p ≤0.05。结果GⅢ:(低温/NS)和 GⅣ:低温/CCHX 在 24、48 和 72 小时后疼痛明显减轻,P= 0.000 I。两个测试组的疼痛在 7 天后均降至无痛。两组的镇痛需求频率差异不大,P=0.27。结论从本研究的结果来看,无论是使用 CHX 还是 NS,低温都有助于减轻疼痛。与 NS 相比,CHX 作为低温材料在有效减轻疼痛的时间依赖性方面表现出不明显的趋势。这可能是由于它的吸附性。要更好地澄清这一点,还需要进一步的研究。
{"title":"Effectiveness of Two Intracanal Irrigation Solutions Delivered Through Cryotherapy on Post-Endodontic Pain Relieve. A Randomized Clinical Trial","authors":"Manal Abdelbaky, mostafa shaker","doi":"10.21608/edj.2024.290051.3040","DOIUrl":"https://doi.org/10.21608/edj.2024.290051.3040","url":null,"abstract":"Aim: The present randomized clinical trial was designed to investigate the effect of cryotherapy (cryo) utilizing chlorhexidine (CHX) as compared to saline (NS) on pain reduction after single visit endodontic treatment. Methodology: Selected patients were seeking emergency treatment of painful symptomatic irreversible pulpitis with symptomatic apical periodontitis for single rooted teeth. Sixty-eight male patients, 25 to 50 years old were distributed randomly in 4 groups of 17 each according to the final irrigation protocol: control (GI): NS at room temperature, control (GII): CHX at room temperature, intervention (GIII): cryo with NS (cryo/NS), , and intervention (G IV): (cryo / CHX) before final obturation in the same visit. Patients were trained and asked to report pain incidence and level after12, 24, 48, 72 hours and at 7 days as well as frequency of analgesic intake. Kruskal Wallis, followed by Dunn`s multiple comparisons test were used for comparison between the 4 groups, while Chi square test was used for qualitative data. The significance level was set at p ≤0.05. Results: G III: (cryo/NS) and G IV: cryo/CHX showed significantly highest pain reduction after 24, 48, and 72 hours P= 0.000 I. Significantly more prolonged pain reduction curve was found in GI: cryo/NS. Pain in both tested groups declined to no pain after 7 days. Frequency of analgesic need was insignificant for the two groups P=0.27. Conclusions: From the results of the present study it appeared clearly that cryo helped in pain reduction whether used with CHX or NS. CHX used as a cryo material showed insignificant trend toward effective time dependent pain reduction as compared to NS. This might be because of its substantivity. Further study is needed to better clarifying this point.","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141697249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colocalization of VEGF and iNOS in Parenchymal and Stromal Cells of Oral Squamous Cell Carcinoma 口腔鳞状细胞癌实质细胞和基质细胞中血管内皮生长因子和 iNOS 的共定位
Pub Date : 2024-07-01 DOI: 10.21608/edj.2024.269833.2939
A. Essa
Background and objectives: Tumor angiogenesis and inflammation perception are intricately linked to cancer progression. Vascular endothelial growth factor (VEGF) controls distinct procedures in angiogenesis of pathological conditions in metabolic functions of cancer cells with the inflammatory cytokine inducible nitric oxide synthase (iNOS) in parenchymal together with stromal cells of oral squamous cell carcinoma (OSCC) as well as assessing microvessel density (MVD). Methods: Immunohistochemistry was applied to analyze VEGF, iNOS as well as CD31 expression within 31 OSCCs paraffin blocks, which grouped into 13 well differentiated, 10 moderately differentiated, and 8 poorly differentiated (paraffin blocks OSCC). Results: Both VEGF and iNOS exhibit strong expression in both parenchymal and stromal cells in all grades of OSCC together with increased MVD. Conclusion: Enhanced expression of VEGF and iNOS together with MVD potentially correlate with OSCC grades.
背景和目的:肿瘤血管生成和炎症感知与癌症进展有着错综复杂的联系。血管内皮生长因子(VEGF)与炎症细胞因子诱导型一氧化氮合酶(iNOS)在口腔鳞状细胞癌(OSCC)的实质细胞和基质细胞中的作用以及微血管密度(MVD)的评估中控制着不同病理条件下癌细胞代谢功能的血管生成过程。方法:免疫组化采用免疫组化方法分析 31 块石蜡切片中 VEGF、iNOS 和 CD31 的表达情况,这些石蜡切片分为 13 个分化良好、10 个中度分化和 8 个分化不良(石蜡切片 OSCC)。结果在所有等级的 OSCC 中,VEGF 和 iNOS 在实质细胞和基质细胞中均有较强的表达,同时 MVD 也有所增加。结论:VEGF 和 iNOS 的表达增强以及 MVD 可能与 OSCC 的分级有关。
{"title":"Colocalization of VEGF and iNOS in Parenchymal and Stromal Cells of Oral Squamous Cell Carcinoma","authors":"A. Essa","doi":"10.21608/edj.2024.269833.2939","DOIUrl":"https://doi.org/10.21608/edj.2024.269833.2939","url":null,"abstract":"Background and objectives: Tumor angiogenesis and inflammation perception are intricately linked to cancer progression. Vascular endothelial growth factor (VEGF) controls distinct procedures in angiogenesis of pathological conditions in metabolic functions of cancer cells with the inflammatory cytokine inducible nitric oxide synthase (iNOS) in parenchymal together with stromal cells of oral squamous cell carcinoma (OSCC) as well as assessing microvessel density (MVD). Methods: Immunohistochemistry was applied to analyze VEGF, iNOS as well as CD31 expression within 31 OSCCs paraffin blocks, which grouped into 13 well differentiated, 10 moderately differentiated, and 8 poorly differentiated (paraffin blocks OSCC). Results: Both VEGF and iNOS exhibit strong expression in both parenchymal and stromal cells in all grades of OSCC together with increased MVD. Conclusion: Enhanced expression of VEGF and iNOS together with MVD potentially correlate with OSCC grades.","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141709126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Preparation Design on the Fracture Resistance of Partial Laminate Veneers. An In-vitro Study 制备设计对部分层压饰面抗断裂性的影响。体外研究
Pub Date : 2024-07-01 DOI: 10.21608/edj.2024.290406.3041
Omnia Nabil, A. S. Idris
Objectives. To evaluate the effect of two preparation designs of partial laminate veneers on the fracture resistance of anterior teeth with full and half incisal edge fracture. Materials and Methods. 48 upper central incisors were divided into four equal groups: two groups simulated completely fractured incisal edge: Group (Full/Cham): with chamfer design and Group (Full/Bev): with bevel design and two groups simulated half fractured incisal edge: Group (Half/Cham): with chamfer design and Group (Half/Bev): with bevel design. Lithium disilicate partial veneers were constructed and cemented using light-curing resin cement. All samples were mounted on universal testing machine to test their fracture resistance. Fractured samples were categorized as restorable or non-restorable based on the crack/fracture extension relative to the cemento-enamel junction. Results. Group (Full/Cham): (361.05 ± 11.39 N) had significantly the highest fracture resistance, followed by Group (Full/Bev): (207.1 ± 10.85 N), while Group (Half/Cham): (123.16 ± 6.63 N) and Group (Half/Bev): (123.75 ± 6.12 N) had significantly the lowest values with insignificant difference between them. All teeth with half incisal edge fracture revealed restorable fractures, while with full incisal edge fracture the percentage dropped to third (33.3%). Conclusions. In full incisal edge fractures, chamfer design had better fracture resistance than bevel design. While in half incisal edge fractures, both designs had similar fracture resistance and restorable mode of failure. Clinical Relevance. The innovative chamfer and bevel designs of partial laminate veneers can be used as a highly conservative approach to restore anterior teeth with full or half fractured incisal edge.
目的评估部分层压贴面的两种制备设计对前牙全切缘和半切缘抗折性的影响。材料和方法。将 48 颗上中切牙平均分为四组:两组模拟切缘完全折断:组(全/Cham):倒角设计,组(全/Bev):斜面设计:组(半/Cham):倒角设计;组(半/Bev):斜面设计。使用光固化树脂粘结剂制作和粘结二硅酸锂部分贴面。将所有样品安装在万能试验机上测试其抗折性。根据裂纹/断裂相对于骨水泥-珐琅质交界处的延伸情况,将断裂样品分为可修复和不可修复两类。结果可修复组(361.05 ± 11.39 N)的抗断裂强度明显最高,其次是(全/Bev)组:(207.1 ± 10.85 N),而(半/Cham)组:(123.16 ± 6.63 N)的抗断裂强度最低:(123.16 ± 6.63 N) 和组别(半/Bev):(123.75 ± 6.12 N)的抗折力明显最低,两者之间的差异不明显。所有半切缘折断的牙齿都显示出可修复的折断,而全切缘折断的比例下降到三分之一(33.3%)。结论在全切缘骨折中,倒角设计比斜面设计具有更好的抗折性。而在半切缘骨折中,两种设计的抗折性和可修复的失败模式相似。临床意义。部分层压贴面的创新倒角和斜面设计可作为一种高度保守的方法,用于修复全切缘或半切缘骨折的前牙。
{"title":"Effect of Preparation Design on the Fracture Resistance of Partial Laminate Veneers. An In-vitro Study","authors":"Omnia Nabil, A. S. Idris","doi":"10.21608/edj.2024.290406.3041","DOIUrl":"https://doi.org/10.21608/edj.2024.290406.3041","url":null,"abstract":"Objectives. To evaluate the effect of two preparation designs of partial laminate veneers on the fracture resistance of anterior teeth with full and half incisal edge fracture. Materials and Methods. 48 upper central incisors were divided into four equal groups: two groups simulated completely fractured incisal edge: Group (Full/Cham): with chamfer design and Group (Full/Bev): with bevel design and two groups simulated half fractured incisal edge: Group (Half/Cham): with chamfer design and Group (Half/Bev): with bevel design. Lithium disilicate partial veneers were constructed and cemented using light-curing resin cement. All samples were mounted on universal testing machine to test their fracture resistance. Fractured samples were categorized as restorable or non-restorable based on the crack/fracture extension relative to the cemento-enamel junction. Results. Group (Full/Cham): (361.05 ± 11.39 N) had significantly the highest fracture resistance, followed by Group (Full/Bev): (207.1 ± 10.85 N), while Group (Half/Cham): (123.16 ± 6.63 N) and Group (Half/Bev): (123.75 ± 6.12 N) had significantly the lowest values with insignificant difference between them. All teeth with half incisal edge fracture revealed restorable fractures, while with full incisal edge fracture the percentage dropped to third (33.3%). Conclusions. In full incisal edge fractures, chamfer design had better fracture resistance than bevel design. While in half incisal edge fractures, both designs had similar fracture resistance and restorable mode of failure. Clinical Relevance. The innovative chamfer and bevel designs of partial laminate veneers can be used as a highly conservative approach to restore anterior teeth with full or half fractured incisal edge.","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141695509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EVALUATION OF THE COLOR CHANGE AND SURFACE ROUGHNESS OF REINFORCED COMPOSITE (BRILIANT CRIOS) AFTER IMMERSION IN ACIDIC BEVERAGE: AN IN-VITRO STUDY 评估强化复合材料(Briliant Crios)在酸性饮料中浸泡后的颜色变化和表面粗糙度:体外研究
Pub Date : 2024-07-01 DOI: 10.21608/edj.2024.271428.2952
shaimaa Rabee Ali, Rana M Sherif, Rasha nabil sami
Objective: Evaluate the color change and surface roughness of reinforced composite (BRILIANT CRIOS) after immersion in artificial saliva then acidic beverage (Pepsi). Materials & Methods: Samples from reinforced composite (BRILIANT CRIOS) were immersed in artificial saliva and acidic beverage (Pepsi). A total of 23 samples were prepared 1mm in thickness and (14 × 12 × 18 (mm) in dimensions. The average color change (Delta E*) was computed following immersion in artificial saliva and an acidic beverage. Using spectrophotometer analysis, color parameters were assessed both before and after the immersion. The surface roughness was measured with a non-contact profilometer. The Shapiro-Wilk test was used for statistical analysis. Data had a parametric distribution, thus we used repeated measures ANOVA and the Bonferroni post hoc test to examine them. The significance level was set at P ≤ 0.05. Results: showed that the color change of Brilliant Crios samples immersed in Pepsi ΔE 2 was significantly higher than artificial saliva ΔE 1 while Pepsi samples had the highest surface roughness rating, followed by baseline samples, while artificial saliva samples had the lowest value. Conclusion: reinforced composite (BRILIANT CRIOS) samples showed color changes above the clinical acceptable limit when immersed in artificial saliva and Pepsi in comparison to surface roughness beyond the clinically acceptable level after immersion in acidic beverage (Pepsi).
目标: 评估强化复合材料(BRILIANT CRIOS)在浸泡人工唾液和酸性饮料(百事可乐)后的颜色变化和表面粗糙度:评估强化复合材料(BRILIANT CRIOS)在人工唾液和酸性饮料(百事可乐)中浸泡后的颜色变化和表面粗糙度。材料与方法:将增强复合材料(BRILIANT CRIOS)样品浸泡在人工唾液和酸性饮料(百事可乐)中。共制备了 23 个厚度为 1 毫米、尺寸为 14 × 12 × 18 毫米的样品。在人工唾液和酸性饮料中浸泡后,计算平均颜色变化(Delta E*)。使用分光光度计分析评估了浸泡前后的颜色参数。表面粗糙度用非接触式轮廓仪测量。统计分析采用 Shapiro-Wilk 检验。数据呈参数分布,因此我们使用重复测量方差分析和 Bonferroni 后检验来检验数据。显著性水平设定为 P ≤ 0.05。结果:浸泡在百事可乐 ΔE 2 中的 Brilliant Crios 样品的颜色变化明显高于人工唾液 ΔE 1,而百事可乐样品的表面粗糙度等级最高,其次是基线样品,而人工唾液样品的数值最低。结论:在人工唾液和百事可乐中浸泡后,增强复合材料(BRILIANT CRIOS)样品的颜色变化超过了临床可接受的限度,而在酸性饮料(百事可乐)中浸泡后,表面粗糙度则超过了临床可接受的水平。
{"title":"EVALUATION OF THE COLOR CHANGE AND SURFACE ROUGHNESS OF REINFORCED COMPOSITE (BRILIANT CRIOS) AFTER IMMERSION IN ACIDIC BEVERAGE: AN IN-VITRO STUDY","authors":"shaimaa Rabee Ali, Rana M Sherif, Rasha nabil sami","doi":"10.21608/edj.2024.271428.2952","DOIUrl":"https://doi.org/10.21608/edj.2024.271428.2952","url":null,"abstract":"Objective: Evaluate the color change and surface roughness of reinforced composite (BRILIANT CRIOS) after immersion in artificial saliva then acidic beverage (Pepsi). Materials & Methods: Samples from reinforced composite (BRILIANT CRIOS) were immersed in artificial saliva and acidic beverage (Pepsi). A total of 23 samples were prepared 1mm in thickness and (14 × 12 × 18 (mm) in dimensions. The average color change (Delta E*) was computed following immersion in artificial saliva and an acidic beverage. Using spectrophotometer analysis, color parameters were assessed both before and after the immersion. The surface roughness was measured with a non-contact profilometer. The Shapiro-Wilk test was used for statistical analysis. Data had a parametric distribution, thus we used repeated measures ANOVA and the Bonferroni post hoc test to examine them. The significance level was set at P ≤ 0.05. Results: showed that the color change of Brilliant Crios samples immersed in Pepsi ΔE 2 was significantly higher than artificial saliva ΔE 1 while Pepsi samples had the highest surface roughness rating, followed by baseline samples, while artificial saliva samples had the lowest value. Conclusion: reinforced composite (BRILIANT CRIOS) samples showed color changes above the clinical acceptable limit when immersed in artificial saliva and Pepsi in comparison to surface roughness beyond the clinically acceptable level after immersion in acidic beverage (Pepsi).","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141710839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Vitro Investigation of Marginal & Internal Adaptation of Two Screw-Retained Implant Supported Crowns: A Comparative Analysis of Direct Optical & Subtractive Reverse Engineering Techniques. 两种螺钉固位种植牙冠边缘和内部适应性的体外研究:直接光学和减法逆向工程技术的对比分析
Pub Date : 2024-07-01 DOI: 10.21608/edj.2024.288919.3037
Heba Ismail, M. Wahsh, A. Aboelfadl, Ingy Nouh
Objectives: The aim of this in-vitro study was to investigate the marginal and internal adaptation of two screw-retained crowns; lithium disilicate and BioHPP using direct optical and subtractive reverse engineering techniques and to calculate the degree of agreement between them. Materials & Methods: Twenty-eight implant analogs were embedded perpendicularly in an auto-polymerizing resin. Implant-supported restorations were designed then milled with CAD wax and divided into 2 groups according to material (n=14): Lithium disilicate and BioHPP. Each group was pressed according to the manufacturer’s instructions. The marginal and internal adaptation of the specimens were analyzed using DOT & subtractive RET. Data were explored for normality using Shapiro-Wilk’s and Levene’s tests and were analyzed using independent and paired t-test for inter and intragroup comparisons respectively with a significance level of p<0.05. Agreement analysis was done using intraclass correlation coefficient (ICC). Results: BioHPP screw-retained implant-supported crowns showed higher marginal gap than lithium disilicate, yet the difference was non-significant when measured using DOT, while it was significant when measured using sRET. Calculated agreement between the two techniques at the marginal level showed that there was a statistically significant moderate agreement between both methods. Regarding internal adpatation, BioHPP had a statistically significant higher internal gap than lithium disilicate group. Conclusions: Supra-structure material affected marginal and internal adaptation of implant-supported restorations. Pressed lithium disilicate crowns showed better marginal and internal adaptation than BioHPP crowns, however, both groups showed clinically acceptable results. DOT and RET were both relevant and showed moderate agreement between them.
研究目的这项体外研究的目的是使用直接光学和减法逆向工程技术研究两种螺钉固位牙冠(二硅酸锂和 BioHPP)的边缘和内部适应性,并计算它们之间的一致程度。材料与方法:将 28 个种植体模拟体垂直嵌入自动聚合树脂中。设计种植体支持的修复体,然后用 CAD 蜡进行研磨,并根据材料分为两组(n=14):二硅酸锂和 BioHPP。每组均按照制造商的说明进行压制。使用 DOT 和减法 RET 分析试样的边缘和内部适应性。使用 Shapiro-Wilk 检验和 Levene 检验对数据进行正态性检验,并分别使用独立 t 检验和配对 t 检验对组间和组内比较进行分析,显著性水平为 p<0.05。采用类内相关系数(ICC)进行一致性分析。结果BioHPP螺钉固位种植体支持冠的边缘间隙高于二硅酸锂冠,但使用DOT测量时差异不显著,而使用sRET测量时差异显著。对两种技术在边缘水平上的一致性进行计算后发现,这两种方法在统计学上具有显著的中度一致性。在内部间隙方面,BioHPP 的内部间隙在统计学上明显高于二硅酸锂组。结论上部结构材料会影响种植体支持修复体的边缘和内部适应性。与 BioHPP 冠相比,压制二硅酸锂冠显示出更好的边缘和内部适应性,但两组都显示出临床可接受的结果。DOT 和 RET 都具有相关性,而且两者之间的一致性适中。
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Egyptian dental journal
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