Pub Date : 2024-07-01DOI: 10.21608/edj.2024.270448.2948
sherif mohsen Al bahrawey, A. Halawa, H. El-Messiry
Background: Dental extraction is one of the most widely performed dental procedures. Socket healing involves tissue repair and regeneration. Different types of materials are used to aid and fasten the healing process such as nano-hydroxy appetite. Objectives: The aim of the present study was to compare the healing potential and potencies for new bone formation of nano-hydroxyapatite crystals and theobromine powder in the healing of extraction Socket in Male Albino rats. Methods: Thirty-eight male Albino rats were used this experiment. Lower left first molar was extracted from each rat. The rats were equally divided into three groups. Each group was subdivided into two subgroups (After one week and after two weeks) from receiving the treatment. control group which didn’t receive any treatment, n-HA group which received –HA and theobromine group which received theobromine. Samples were stained with H&E, Masson trichrome and Beta-catenin then assessed under light microscope. One-way ANOVA followed by Tukey’s post hoc test was used to analyze data. Results: H&E section showed that theobromine group has more potential in inducing new bone formation than n-HA group.Masson trichrome stain: reveled that theobromine group induced mature bone formation compared to n-HA group.Beta-Catenin stain: All groups showed negative reactions except theobromine group 3B and n-HA group 2B. Conclusions: Nanohydroxy apatite crystals and theobromine enhance the socket healing, theobromine has superior effect compared with the nanohydroxy apatite. the effect of the treatment material is more obvious in the second week of socket healing.
{"title":"“Comparative Study on the Effect of Nano- hydroxyapatite and Theobromine on Healing of Extraction Socket in Albino Rats (Histological and Immuno-Histochemical Study)’’","authors":"sherif mohsen Al bahrawey, A. Halawa, H. El-Messiry","doi":"10.21608/edj.2024.270448.2948","DOIUrl":"https://doi.org/10.21608/edj.2024.270448.2948","url":null,"abstract":"Background: Dental extraction is one of the most widely performed dental procedures. Socket healing involves tissue repair and regeneration. Different types of materials are used to aid and fasten the healing process such as nano-hydroxy appetite. Objectives: The aim of the present study was to compare the healing potential and potencies for new bone formation of nano-hydroxyapatite crystals and theobromine powder in the healing of extraction Socket in Male Albino rats. Methods: Thirty-eight male Albino rats were used this experiment. Lower left first molar was extracted from each rat. The rats were equally divided into three groups. Each group was subdivided into two subgroups (After one week and after two weeks) from receiving the treatment. control group which didn’t receive any treatment, n-HA group which received –HA and theobromine group which received theobromine. Samples were stained with H&E, Masson trichrome and Beta-catenin then assessed under light microscope. One-way ANOVA followed by Tukey’s post hoc test was used to analyze data. Results: H&E section showed that theobromine group has more potential in inducing new bone formation than n-HA group.Masson trichrome stain: reveled that theobromine group induced mature bone formation compared to n-HA group.Beta-Catenin stain: All groups showed negative reactions except theobromine group 3B and n-HA group 2B. Conclusions: Nanohydroxy apatite crystals and theobromine enhance the socket healing, theobromine has superior effect compared with the nanohydroxy apatite. the effect of the treatment material is more obvious in the second week of socket healing.","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141699903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/edj.2024.292081.3050
Yara Y Mouselhy, Iman Mostafa Abdel Meguid, Bassant M Bahgat, Waleed F Esmael, Ahmed Abo Zekry, Hala el kammar
Background: odontogenic lesions comprise a diverse group exhibiting a wide range of clinical and biological behaviors, demanding a meticulous understanding for accurate diagnosis and management. In response to DNA damage, the p53 tumor suppressor protein functions as a key regulator, inducing either cell cycle arrest or apoptosis. Mutations in the p53 gene are frequently observed in human cancers; however, the role of p53 expression in odontogenic lesions remains unclear. Material and methods: A retrospective design was employed to evaluate and compare p53 protein expression patterns, detected by immunohistochemistry, in ameloblastoma, ameloblastic carcinoma, dentigerous cyst
背景：牙源性病变种类繁多，临床和生物学表现各异，需要细致了解才能准确诊断和处理。针对 DNA 损伤，p53 肿瘤抑制蛋白起着关键的调节作用，可诱导细胞周期停止或凋亡。p53 基因突变在人类癌症中经常出现，但 p53 在牙源性病变中的作用仍不清楚。材料和方法：采用回顾性设计，通过免疫组织化学方法评估和比较了牙釉质母细胞瘤、牙釉质癌、牙性囊肿和牙源性病变中 p53 蛋白的表达模式。
{"title":"Aberrant Immunohistochemical Expression of P53 in Ameloblastoma, Ameloblastic Carcinoma, Dentigerous Cyst and Odontogenic Keratocyst: A comparative Study","authors":"Yara Y Mouselhy, Iman Mostafa Abdel Meguid, Bassant M Bahgat, Waleed F Esmael, Ahmed Abo Zekry, Hala el kammar","doi":"10.21608/edj.2024.292081.3050","DOIUrl":"https://doi.org/10.21608/edj.2024.292081.3050","url":null,"abstract":"Background: odontogenic lesions comprise a diverse group exhibiting a wide range of clinical and biological behaviors, demanding a meticulous understanding for accurate diagnosis and management. In response to DNA damage, the p53 tumor suppressor protein functions as a key regulator, inducing either cell cycle arrest or apoptosis. Mutations in the p53 gene are frequently observed in human cancers; however, the role of p53 expression in odontogenic lesions remains unclear. Material and methods: A retrospective design was employed to evaluate and compare p53 protein expression patterns, detected by immunohistochemistry, in ameloblastoma, ameloblastic carcinoma, dentigerous cyst","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141693964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/edj.2024.271644.2953
Doaa El-Bedewy, Mohamed Mostafa Zayed, Ahmad Mostafa Hussein, A. Rashed
Objectives: Evaluate the potential of amelogenin and chitosan to repair eroded dentin at different times by means of a chemical element analysis. Methodology : Twelve human lower first molars were collected. Radicular part was removed, while coronal part was sectioned mesiodistally. Two dentin slabs were obtained from each molar. Samples were immersed in Coca Cola beverage (Coca-Cola® Co., Egypt) for 25 hours. Samples in group I were stored in artificial saliva, while in group II they were treated with agarose hydrogel. Agarose hydrogel was loaded with chitosan in group III and with Emdogain in group IV. Hydrogels were applied to samples for 5 hours. This procedure was repeated daily for 15 days. Dentin mineral contents (Ca & P) were tested using energy dispersive analytical X-ray. Results: The baseline mean values of Ca & P in sound dentin samples were (23.08±2.23) & (7.91±3.09), while were significantly decreased into (6.88±2.30) & (4.04±1.28) after immersion in Coca Cola. On comparing Ca & P contents of different groups after 5 days treatment, ANOVA showed no significant differences in both elements, while after 10 days a highly statistically significant differences were recorded in all groups (p=0.000). After 15 days, a highly significant differences in Ca content were recorded (p=0.000), while no significant differences were recorded in P content (p=0.167). Emdogain group represented the best results. Conclusion: Emdogain exhibits promising remineralizing effect on erosive dentin, as it has the highest mean difference when compared to chitosan and control groups.
目标：通过化学元素分析，评估羊胎素和壳聚糖在不同时期修复受损牙本质的潜力。方法：收集 12 颗人类下第一臼齿。根部被切除，冠部被中线切片。从每颗臼齿上获取两块牙本质板。将样本浸泡在可口可乐饮料（埃及可口可乐公司）中 25 小时。第一组样本保存在人工唾液中，第二组样本用琼脂糖水凝胶处理。第三组的琼脂糖水凝胶含有壳聚糖，第四组的琼脂糖水凝胶含有 Emdogain。将水凝胶涂抹在样本上 5 小时。每天重复这一过程，持续 15 天。使用能量色散分析 X 射线检测牙本质矿物质含量（钙和磷）。结果健全牙本质样本中 Ca 和 P 的基线平均值分别为 (23.08±2.23) 和 (7.91±3.09)，而在可口可乐中浸泡后，Ca 和 P 的基线平均值明显降低为 (6.88±2.30) 和 (4.04±1.28)。在处理 5 天后，比较不同组的钙和磷含量，方差分析显示这两种元素没有明显差异，而在处理 10 天后，所有组的钙和磷含量都有非常明显的统计学差异（p=0.000）。15 天后，钙含量有非常显著的差异（p=0.000），而磷含量没有显著差异（p=0.167）。Emdogain 组的结果最好。结论与壳聚糖组和对照组相比，Emdogain 对腐蚀性牙本质具有良好的再矿化效果，其平均差异最大。
{"title":"Quantitative Evaluation of The Power of Amelogenin and Chitosan in Natural Repair of Dentin Defects Using Energy‑Dispersive Analytical X‑ray Element Analysis","authors":"Doaa El-Bedewy, Mohamed Mostafa Zayed, Ahmad Mostafa Hussein, A. Rashed","doi":"10.21608/edj.2024.271644.2953","DOIUrl":"https://doi.org/10.21608/edj.2024.271644.2953","url":null,"abstract":"Objectives: Evaluate the potential of amelogenin and chitosan to repair eroded dentin at different times by means of a chemical element analysis. Methodology : Twelve human lower first molars were collected. Radicular part was removed, while coronal part was sectioned mesiodistally. Two dentin slabs were obtained from each molar. Samples were immersed in Coca Cola beverage (Coca-Cola® Co., Egypt) for 25 hours. Samples in group I were stored in artificial saliva, while in group II they were treated with agarose hydrogel. Agarose hydrogel was loaded with chitosan in group III and with Emdogain in group IV. Hydrogels were applied to samples for 5 hours. This procedure was repeated daily for 15 days. Dentin mineral contents (Ca & P) were tested using energy dispersive analytical X-ray. Results: The baseline mean values of Ca & P in sound dentin samples were (23.08±2.23) & (7.91±3.09), while were significantly decreased into (6.88±2.30) & (4.04±1.28) after immersion in Coca Cola. On comparing Ca & P contents of different groups after 5 days treatment, ANOVA showed no significant differences in both elements, while after 10 days a highly statistically significant differences were recorded in all groups (p=0.000). After 15 days, a highly significant differences in Ca content were recorded (p=0.000), while no significant differences were recorded in P content (p=0.167). Emdogain group represented the best results. Conclusion: Emdogain exhibits promising remineralizing effect on erosive dentin, as it has the highest mean difference when compared to chitosan and control groups.","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141694331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/edj.2024.286438.3030
Ahmed Ali Youssef, Essam Fawzy Mahmoud
Aim: Comparing the fracture resistance of roots obturated with gutta-percha using two different sealers. Materials and methods: Forty human single rooted mandibular premolars teeth were decoronated and standardized to 16 mm length. Instrumentation was done using PLEX-V system rotary file system up to PLEX-V 40.04. Samples were randomly classified into two equal experimental groups according to the type of sealer used for obturation of root canals (Adseal and Ceraseal). The roots were aligned vertically along their long axis in self-curing acrylic blocks and mounted on the universal testing machine to measure the fracture resistance. Data collected and statistically analyzed. Results: The fracture resistance values of Adseal group were higher than Ceraseal group. A statistically significant difference was found between Adseal group (I) and Ceraseal group (II) where (p<0.001). Conclusion: Within the limitation of this study, it can be concluded that the obturation using Adseal resin sealer combined with gutta percha points significantly increases the fracture resistance of endodontically treated teeth compared to Ceraseal bioceramic sealer combined with gutta percha points.
{"title":"Effect of root canal obturation using resin and bio-ceramic sealers on reinforcement of endodontically treated teeth.","authors":"Ahmed Ali Youssef, Essam Fawzy Mahmoud","doi":"10.21608/edj.2024.286438.3030","DOIUrl":"https://doi.org/10.21608/edj.2024.286438.3030","url":null,"abstract":"Aim: Comparing the fracture resistance of roots obturated with gutta-percha using two different sealers. Materials and methods: Forty human single rooted mandibular premolars teeth were decoronated and standardized to 16 mm length. Instrumentation was done using PLEX-V system rotary file system up to PLEX-V 40.04. Samples were randomly classified into two equal experimental groups according to the type of sealer used for obturation of root canals (Adseal and Ceraseal). The roots were aligned vertically along their long axis in self-curing acrylic blocks and mounted on the universal testing machine to measure the fracture resistance. Data collected and statistically analyzed. Results: The fracture resistance values of Adseal group were higher than Ceraseal group. A statistically significant difference was found between Adseal group (I) and Ceraseal group (II) where (p<0.001). Conclusion: Within the limitation of this study, it can be concluded that the obturation using Adseal resin sealer combined with gutta percha points significantly increases the fracture resistance of endodontically treated teeth compared to Ceraseal bioceramic sealer combined with gutta percha points.","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141709106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/edj.2024.270550.2946
Marwa Mohammed Abd eltwab, Mohammed Moustafa Shalaby, Eman Hamdy Mohammed, hanaa farouk mahmoud
Aim: is to assess antimicrobial activity and diametral tensile strength (DTS) of glass ionomer cement (GIC) modified with plant extract mixture (PE). Material and Methods: conventional GIC was utilized. It is treated with PE. Alcoholic extract of Aloe Vera (AVE) was prepared. Using a Soxhlet extractor, an alcoholic extract of Salvadora persica(SPE) was produced. The PE was incorporated to the glass ionomer liquid (GIL).Forty Samples were fabricated using 6 mm diameter and 3 mm thick split-Teflon molds. Samples were divided into two main groups (n=20): group I (antimicrobial test) and group II (diametral tensile strength test). Each group was divided into Four subgroups (n=5) according to liquid composition into: subgroup (A): control subgroup, subgroup (B): 1.5GIL: 1PE, subgroup(C): 1GIL:1PE and subgroup (D): 1GIL:1.5PE. Antimicrobial activity against Streptococcus mutants (SM) was appraised by the agar well diffusion assay method. Universal testing machine was utilized to determine (DTS). Results : One way ANOVA test for quantitative data between the four groups followed by post hoc LSD analysis between each two groups were used. The highest antimicrobial activity was in subgroup ID (1GIL:1.5 PE) and the lowest value was in control subgroup. The highest DTS was in subgroup IIC (1GIL:1PE) and lowest was in control subgroup. Conclusions: Plant extract significantly improved the antimicrobial activity of GIC against SM. The DTS of GIC was improved within limits by addition of PE only up to (1 GIL: 1 PE).
目的：评估用植物提取混合物（PE）改性的玻璃离子水泥（GIC）的抗菌活性和直径拉伸强度（DTS）。材料和方法：使用传统的 GIC。用 PE 对其进行处理。制备芦荟酒精提取物（AVE）。使用索氏萃取器，制备出 Salvadora persica 的酒精萃取物（SPE）。使用直径为 6 毫米、厚度为 3 毫米的分体式聚四氟乙烯模具制作了 40 个样品。样品分为两大组（n=20）：第一组（抗菌测试）和第二组（直径拉伸强度测试）。每组按液体成分分为四个子组（n=5）：子组（A）：对照子组；子组（B）：1.5GIL：1PE 子组；子组（C）：1.5GIL：1PE 子组；子组（D）：1.5GIL：1PE 子组：1.5GIL：1PE，子组（C）：1GIL：1PE 和子组（D）：1GIL：1.5PE。琼脂井扩散试验法评估了对链球菌突变体（SM）的抗菌活性。利用万能试验机测定（DTS）。结果：对四组之间的定量数据进行了单向方差分析，然后对每两组之间的数据进行了事后 LSD 分析。抗菌活性最高的是 ID 亚组（1GIL:1.5 PE），最低的是对照亚组。DTS值最高的是IIC亚组（1GIL:1PE），最低的是对照亚组。结论植物提取物明显提高了 GIC 对 SM 的抗菌活性。加入 PE 后，GIC 的 DTS 在一定范围内得到改善，最高可达（1 GIL：1 PE）。
{"title":"Evaluation of antimicrobial activity and tensile strength of glass ionomer cement modified with plant extract mixture","authors":"Marwa Mohammed Abd eltwab, Mohammed Moustafa Shalaby, Eman Hamdy Mohammed, hanaa farouk mahmoud","doi":"10.21608/edj.2024.270550.2946","DOIUrl":"https://doi.org/10.21608/edj.2024.270550.2946","url":null,"abstract":"Aim: is to assess antimicrobial activity and diametral tensile strength (DTS) of glass ionomer cement (GIC) modified with plant extract mixture (PE). Material and Methods: conventional GIC was utilized. It is treated with PE. Alcoholic extract of Aloe Vera (AVE) was prepared. Using a Soxhlet extractor, an alcoholic extract of Salvadora persica(SPE) was produced. The PE was incorporated to the glass ionomer liquid (GIL).Forty Samples were fabricated using 6 mm diameter and 3 mm thick split-Teflon molds. Samples were divided into two main groups (n=20): group I (antimicrobial test) and group II (diametral tensile strength test). Each group was divided into Four subgroups (n=5) according to liquid composition into: subgroup (A): control subgroup, subgroup (B): 1.5GIL: 1PE, subgroup(C): 1GIL:1PE and subgroup (D): 1GIL:1.5PE. Antimicrobial activity against Streptococcus mutants (SM) was appraised by the agar well diffusion assay method. Universal testing machine was utilized to determine (DTS). Results : One way ANOVA test for quantitative data between the four groups followed by post hoc LSD analysis between each two groups were used. The highest antimicrobial activity was in subgroup ID (1GIL:1.5 PE) and the lowest value was in control subgroup. The highest DTS was in subgroup IIC (1GIL:1PE) and lowest was in control subgroup. Conclusions: Plant extract significantly improved the antimicrobial activity of GIC against SM. The DTS of GIC was improved within limits by addition of PE only up to (1 GIL: 1 PE).","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141699375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/edj.2024.288701.3036
Ahmed Adel Abdelaziz, Heba fathy Elemam, Ahmed Hamdy Abdu
Objectives: This in-vitro study was designed to evaluate the remineralizing potential of (Peganum harmala) as a natural plant, niosome loaded harmala extract versus sodium fluoride on demineralized enamel surface. Materials and methods: A 90 caries-free upper first premolar teeth were collected. The specimens were cut 2 mm in a horizontal plane, sectioning of the coronal part into two halves resulting in 180 specimens. Then, embedded in acrylic blocks. Specimens were then immersed in demineralizing solution of 0.3% citric acid for 8 hours to produce artificial caries-like lesions. The specimens randomly divided into five groups: group (A) Peganum harmala extract , group (B) niosome loaded harmala, group (C) sodium fluoride, group (D) positive control, group (E) a negative control. Two concentration groups (5% and 10%), two different time (20 days and 40 days). Specimens of each group were examined for microhardness measurement, data was then recorded, statistically analyzed using analysis of variance (ANOVA). Also, specimens were examined using scanning electron microscopy (SEM). Energy Dispersive X-ray analysis (EDX). Results: 10% concentrations appeared more effective than the 5% in all tested groups. The median hardness for 10% harmala was 176.4.6 in 40 days compared to 151.6 for 5% harmala. Also, niosome 10% showed the highest median microhardness overall (243.6 in 40 days). Also, there was an increase in microhardness values from 20 to 40 days for all preparations. SEM results and EDXA analysis confirmed these observations. Conclusions: P. harmala plant extract and niosome loaded harmala enhanced the remineralization potential of demineralized enamel surface.
{"title":"THE REMINERALIZING POTENTIAL OF NATURAL DRUG LOADED NIOSOME VERSUS ITS EXTRACT ON DEMINERALIZED ENAMEL","authors":"Ahmed Adel Abdelaziz, Heba fathy Elemam, Ahmed Hamdy Abdu","doi":"10.21608/edj.2024.288701.3036","DOIUrl":"https://doi.org/10.21608/edj.2024.288701.3036","url":null,"abstract":"Objectives: This in-vitro study was designed to evaluate the remineralizing potential of (Peganum harmala) as a natural plant, niosome loaded harmala extract versus sodium fluoride on demineralized enamel surface. Materials and methods: A 90 caries-free upper first premolar teeth were collected. The specimens were cut 2 mm in a horizontal plane, sectioning of the coronal part into two halves resulting in 180 specimens. Then, embedded in acrylic blocks. Specimens were then immersed in demineralizing solution of 0.3% citric acid for 8 hours to produce artificial caries-like lesions. The specimens randomly divided into five groups: group (A) Peganum harmala extract , group (B) niosome loaded harmala, group (C) sodium fluoride, group (D) positive control, group (E) a negative control. Two concentration groups (5% and 10%), two different time (20 days and 40 days). Specimens of each group were examined for microhardness measurement, data was then recorded, statistically analyzed using analysis of variance (ANOVA). Also, specimens were examined using scanning electron microscopy (SEM). Energy Dispersive X-ray analysis (EDX). Results: 10% concentrations appeared more effective than the 5% in all tested groups. The median hardness for 10% harmala was 176.4.6 in 40 days compared to 151.6 for 5% harmala. Also, niosome 10% showed the highest median microhardness overall (243.6 in 40 days). Also, there was an increase in microhardness values from 20 to 40 days for all preparations. SEM results and EDXA analysis confirmed these observations. Conclusions: P. harmala plant extract and niosome loaded harmala enhanced the remineralization potential of demineralized enamel surface.","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141715656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/edj.2024.281230.2997
tarek mahmoud nasser, Abeer Gawish, Maii Shafik, Sara Elkabbany, Gasser M Elewa
Objective : This study aimed to clinically investigate the effectiveness of laser photobiomodulation (laser PBM) using flat-top beam profile modifier in acceleration of canine retraction. The expression of nuclear factor kappa-Β ligand (RANKL) that is involved in alveolar bone remodeling was additionally assessed. Material and Methods: The current split-mouth randomized controlled trial involved twenty patients undergoing extractive orthodontic therapy due to the eruption of ectopic canines. A total of forty canines were assigned to two groups: Group I, which underwent laser irradiation, and Group II, which did not receive irradiation. The canines were evaluated at T0 (pre-retraction), T1 (one month post-retraction), T2 (two months), and T3 (three months) for total retraction displacement. RANKL gingival crevicular fluid samples were collected on days 0, 7, 14, and 30 during laser photobiostimulation sessions. Probing depth was also assessed as a secondary outcome at baseline and three months after the procedure. Results
{"title":"Effect of 980 nm Laser Photobiomodulation Using Flat-Top Beam Profile Modifier in Acceleration of Canine Retraction: A Randomized Clinical Trial","authors":"tarek mahmoud nasser, Abeer Gawish, Maii Shafik, Sara Elkabbany, Gasser M Elewa","doi":"10.21608/edj.2024.281230.2997","DOIUrl":"https://doi.org/10.21608/edj.2024.281230.2997","url":null,"abstract":"Objective : This study aimed to clinically investigate the effectiveness of laser photobiomodulation (laser PBM) using flat-top beam profile modifier in acceleration of canine retraction. The expression of nuclear factor kappa-Β ligand (RANKL) that is involved in alveolar bone remodeling was additionally assessed. Material and Methods: The current split-mouth randomized controlled trial involved twenty patients undergoing extractive orthodontic therapy due to the eruption of ectopic canines. A total of forty canines were assigned to two groups: Group I, which underwent laser irradiation, and Group II, which did not receive irradiation. The canines were evaluated at T0 (pre-retraction), T1 (one month post-retraction), T2 (two months), and T3 (three months) for total retraction displacement. RANKL gingival crevicular fluid samples were collected on days 0, 7, 14, and 30 during laser photobiostimulation sessions. Probing depth was also assessed as a secondary outcome at baseline and three months after the procedure. Results","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141715633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/edj.2024.279155.2990
Mohammed Zuhair Abu Nahla, Badawy Abu El Mahasen Badawy, Abdelrahman Soliman Badran
Aim : This study evaluated the fracture resistance of endocrowns with two marginal preparation designs and manufactured with two all ceramic materials. Methods : Twenty endodontically treated maxillary premolar teeth were prepared to receive endocrown restorations and divided into two equal main groups according to the preparation designs; endocrowns with butt joint design and endocrowns with ferrule design (n=10). The main groups were subdivided into two equal subgroups according to all ceramic material used; endocrowns manufactured from Vita Ambria and endocrowns manufactured from Vita Suprinity (n=5). The endocrown restorations were cemented to the prepared teeth using dual cured self-adhesive resin cement. The specimens were subjected to thermo-cycling. All specimens were subjected to a compressive force until fracture by using universal testing machine. The maximum compressive force was recorded for all the specimens, then the failure modes were examined using a digital microscope. Results : Regarding the two materials effect, there were non-significant difference between Vita Ambria and Vita Suprinity on fracture resistance (P=0.66). Regarding the two marginal preparation designs effect, there were non-significant difference between butt joint and ferrule designs on fracture resistance (P=0.73). Regarding the failure mode, there was non-significant difference between all failure mode patterns in all groups except Vita Suprinity with butt joint design. Conclusion: There was no significant difference between Vita Ambria and Vita Suprinity endocrowns, either using ferrule or butt joint design in this study.
目的：本研究评估了采用两种边缘预备设计和两种全瓷材料制造的内冠的抗折性。方法：将 20 颗经过根管治疗的上颌前磨牙制备为内冠修复体，并根据制备设计分为两个相等的主组：对接设计的内冠和卡环设计的内冠（n=10）。根据使用的所有陶瓷材料，主组又分为两个相等的亚组：由 Vita Ambria 制成的内冠和由 Vita Suprinity 制成的内冠（n=5）。内冠修复体使用双固化自粘树脂粘结剂粘结在制备好的牙齿上。试样经过热循环处理。使用万能试验机对所有试样施加压缩力直至断裂。记录所有试样的最大压缩力，然后使用数码显微镜检查其破坏模式。结果：在两种材料的影响方面，Vita Ambria 和 Vita Suprinity 对抗折性的影响差异不显著（P=0.66）。在两种边缘制备设计的影响方面，对接设计和卡套设计对抗折性的影响差异不显著（P=0.73）。在失效模式方面，除 Vita Suprinity 与对接设计外，其他各组的所有失效模式均无显著差异。结论在这项研究中，Vita Ambria 和 Vita Suprinity 内冠无论是采用套圈设计还是对接设计都没有明显差异。
{"title":"Influence of Different Marginal Preparation Designs on the Fracture Resistance of Vita Ambria and Vita Suprinity Endocrowns (An In Vitro Study )","authors":"Mohammed Zuhair Abu Nahla, Badawy Abu El Mahasen Badawy, Abdelrahman Soliman Badran","doi":"10.21608/edj.2024.279155.2990","DOIUrl":"https://doi.org/10.21608/edj.2024.279155.2990","url":null,"abstract":"Aim : This study evaluated the fracture resistance of endocrowns with two marginal preparation designs and manufactured with two all ceramic materials. Methods : Twenty endodontically treated maxillary premolar teeth were prepared to receive endocrown restorations and divided into two equal main groups according to the preparation designs; endocrowns with butt joint design and endocrowns with ferrule design (n=10). The main groups were subdivided into two equal subgroups according to all ceramic material used; endocrowns manufactured from Vita Ambria and endocrowns manufactured from Vita Suprinity (n=5). The endocrown restorations were cemented to the prepared teeth using dual cured self-adhesive resin cement. The specimens were subjected to thermo-cycling. All specimens were subjected to a compressive force until fracture by using universal testing machine. The maximum compressive force was recorded for all the specimens, then the failure modes were examined using a digital microscope. Results : Regarding the two materials effect, there were non-significant difference between Vita Ambria and Vita Suprinity on fracture resistance (P=0.66). Regarding the two marginal preparation designs effect, there were non-significant difference between butt joint and ferrule designs on fracture resistance (P=0.73). Regarding the failure mode, there was non-significant difference between all failure mode patterns in all groups except Vita Suprinity with butt joint design. Conclusion: There was no significant difference between Vita Ambria and Vita Suprinity endocrowns, either using ferrule or butt joint design in this study.","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141696890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/edj.2024.287997.3032
M. Shamaa, Dina Samy Farahat, M. Tawfik
Objective: To investigate the influence of the most frequently utilized mouthrinses on the force degradation of different elastomeric chains. Methodology: Conventional and memory elastomeric chains were attained from two different manufacturers with a total of 320 specimens. Each of the 4 chain types was divided into two groups to deliver light (200g) and heavy forces (350g) (n= 40). Each group was further divided into 4 subgroups (n=10): a control one where the elastomeric chains were immersed in deionized water and three experimental groups immersed in a sodium fluoride (NaF) containing mouthrinse, a whitening mouthrinse and an alcohol containing mouthrinse. The force decay percent was measured over 5 time points. Results: Force decay was significantly higher in alcohol containing mouthrinse group at day 1 compared to other groups followed by a marginal significance. In the whitening group; force decay was non-significantly higher than that in sodium fluoride followed by the control group . There was no significant difference in force degeneration between the two companies. In conventional chain group; there was a significantly higher force decay (p<.001) compared to memory one with the greatest decrease in the first day till the second week, then both reached a plateau and the force remained nearly constant at weeks 3 & 4. No significant difference was detected between light and heavy force application. Conclusion: Alcohol containing mouthrinses can intensify force decay in elastomeric chains more than bleaching and NaF mouthrinses. Memory elastomeric chains are recommended as they exhibited less force decay compared to conventional ones.
{"title":"Changes in the Force Decay of Orthodontic Elastomeric Chains after Immersion in Different Mouthrinses","authors":"M. Shamaa, Dina Samy Farahat, M. Tawfik","doi":"10.21608/edj.2024.287997.3032","DOIUrl":"https://doi.org/10.21608/edj.2024.287997.3032","url":null,"abstract":"Objective: To investigate the influence of the most frequently utilized mouthrinses on the force degradation of different elastomeric chains. Methodology: Conventional and memory elastomeric chains were attained from two different manufacturers with a total of 320 specimens. Each of the 4 chain types was divided into two groups to deliver light (200g) and heavy forces (350g) (n= 40). Each group was further divided into 4 subgroups (n=10): a control one where the elastomeric chains were immersed in deionized water and three experimental groups immersed in a sodium fluoride (NaF) containing mouthrinse, a whitening mouthrinse and an alcohol containing mouthrinse. The force decay percent was measured over 5 time points. Results: Force decay was significantly higher in alcohol containing mouthrinse group at day 1 compared to other groups followed by a marginal significance. In the whitening group; force decay was non-significantly higher than that in sodium fluoride followed by the control group . There was no significant difference in force degeneration between the two companies. In conventional chain group; there was a significantly higher force decay (p<.001) compared to memory one with the greatest decrease in the first day till the second week, then both reached a plateau and the force remained nearly constant at weeks 3 & 4. No significant difference was detected between light and heavy force application. Conclusion: Alcohol containing mouthrinses can intensify force decay in elastomeric chains more than bleaching and NaF mouthrinses. Memory elastomeric chains are recommended as they exhibited less force decay compared to conventional ones.","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141700628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/edj.2024.284316.3018
M. Shamaa, S. Ghorab, Nehal F. Albelasy
Objective: To develop an innovative self-cure orthodontic acrylic resin containing 2-methacryloyloxyethyl phosphorylcholine (MPC) and explore the impact on protein-repellent capacity, antifungal activity, surface roughness and flexural strength. Materials and Methods: MPC was added to polymethyl Methacrylate PMMA resin in three different concentrations forming four groups (0 [control], 1.5, 3, and 4.5%). The protein adsorption was assessed utilizing a micro bicinchoninic acid method. Candida albicans biofilm activity was estimated via colony forming unit counts. Surface roughness was evaluated utilizing a Mitutoyo surface roughness tester. Flexural strength was tested in three-point flexure utilizing a Universal Testing Machine. Data were statistically analyzed using ANOVA and Tukey HSD tests (α = 0.05). Results: Incorporating MPC into the self-cure orthodontic acrylic resin significantly reduced both protein adsorption and C. albicans CFU compared to control group (p < 0.001). Adding 4.5 wt% MPC to the self-cure orthodontic PMMA resin raised the roughness values significantly (p = 0.012), while adding 1.5% and 3 % MPC resulted in no difference in roughness values to that of the control group (p > 0.05). The incorporation of 3 wt% MPC into PMMA resin significantly increased the flexural strength (P < 0.05). However, PMMA resin incorporating 4.5 wt% MPC revealed significant reduction in flexural strength compared with the control group (p = 0.009). Conclusion: A novel removable acrylic orthodontic appliance material incorporating 3 wt% MPC could achieve a promising protein repellent and antifungal activity without adversely affecting the surface roughness and flexural strength of PMMA resins.
{"title":"Development of a Novel Removable Acrylic Orthodontic Appliance Material with Protein - Repellent and Antifungal Properties","authors":"M. Shamaa, S. Ghorab, Nehal F. Albelasy","doi":"10.21608/edj.2024.284316.3018","DOIUrl":"https://doi.org/10.21608/edj.2024.284316.3018","url":null,"abstract":"Objective: To develop an innovative self-cure orthodontic acrylic resin containing 2-methacryloyloxyethyl phosphorylcholine (MPC) and explore the impact on protein-repellent capacity, antifungal activity, surface roughness and flexural strength. Materials and Methods: MPC was added to polymethyl Methacrylate PMMA resin in three different concentrations forming four groups (0 [control], 1.5, 3, and 4.5%). The protein adsorption was assessed utilizing a micro bicinchoninic acid method. Candida albicans biofilm activity was estimated via colony forming unit counts. Surface roughness was evaluated utilizing a Mitutoyo surface roughness tester. Flexural strength was tested in three-point flexure utilizing a Universal Testing Machine. Data were statistically analyzed using ANOVA and Tukey HSD tests (α = 0.05). Results: Incorporating MPC into the self-cure orthodontic acrylic resin significantly reduced both protein adsorption and C. albicans CFU compared to control group (p < 0.001). Adding 4.5 wt% MPC to the self-cure orthodontic PMMA resin raised the roughness values significantly (p = 0.012), while adding 1.5% and 3 % MPC resulted in no difference in roughness values to that of the control group (p > 0.05). The incorporation of 3 wt% MPC into PMMA resin significantly increased the flexural strength (P < 0.05). However, PMMA resin incorporating 4.5 wt% MPC revealed significant reduction in flexural strength compared with the control group (p = 0.009). Conclusion: A novel removable acrylic orthodontic appliance material incorporating 3 wt% MPC could achieve a promising protein repellent and antifungal activity without adversely affecting the surface roughness and flexural strength of PMMA resins.","PeriodicalId":11504,"journal":{"name":"Egyptian dental journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141692692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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