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Correlation between Hyperuricemia and Severity of Coronary Artery Disease Detected by Coronary Angiography in Men and Women 男性和女性冠状动脉造影检测高尿酸血症与冠状动脉疾病严重程度的相关性
Pub Date : 2022-10-01 DOI: 10.21608/ejmr.2022.263555
Mohammed Madbouly, A. Boghdady, Y. Abd el Hady, Khaled R Abd El Meguid
: The association between serum uric acid and ischemic heart disease remains controversial and serum uric acid has not yet been established as cardiovascular risk factor. Our objective was to study the association of serum uric acid level with angiographic severity of coronary artery disease in males and females with ischemic heart disease. This observational study was conducted on two hundred patients divided into one hundred male patient, subdivided into fifty patient with elevated SUA and fifty patient with normal SUA and one hundred female patient subdivided into fifty patient with elevated SUA and fifty patient with normal SUA underwent coronary angiography for detection of CAD in cath lab unit of cardiology department of Beni-Suef and Sohag university. The severity of CAD was assessed on the basis of Gensini score and clinical vessel score. For all groups, conventional risk factors, levels of serum uric acid, and other biochemical markers were assessed.
血清尿酸与缺血性心脏病之间的关系仍有争议,血清尿酸尚未被确定为心血管危险因素。我们的目的是研究血清尿酸水平与男性和女性缺血性心脏病冠状动脉疾病血管造影严重程度的关系。本观察性研究将200例患者分为100例男性患者,再分为50例SUA升高患者和50例SUA正常患者,100例女性患者再分为50例SUA升高患者和50例SUA正常患者,在贝尼苏夫苏哈格大学心内科导管实验室行冠状动脉造影检测冠心病。根据Gensini评分和临床血管评分评估冠心病的严重程度。对所有组进行常规危险因素、血清尿酸水平和其他生化指标的评估。
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引用次数: 0
The impact of Diaphragmatic Dysfunction assessed by chest ultrasound on noninvasive ventilation outcome in patients with acute exacerbation of chronic obstructive pulmonary disease. 胸部超声评估膈功能障碍对慢性阻塞性肺疾病急性加重患者无创通气结果的影响
Pub Date : 2022-10-01 DOI: 10.21608/ejmr.2022.263842
N. Laz, Z. Hashim, Waleed R. Arafat
The Abstract: Background : Noninvasive ventilation (NIV) is now seen as first-line treatment in patients with acute exacerbation of chronic obstructive pulmonary disease and respiratory acidosis (AECOPD). Therefore, the identification of the predictive factors of NIV failure could assist clinicians in detecting the patients at greater risk of negative outcomes. One of these factors is the diaphragmatic dysfunction (DD). Although the measurement of trans-diaphragmatic pressure is the gold current standard for assessing diaphragmatic function, ultrasonography (US) of the diaphragm at the bedside is capable of identifying (DD) in several clinical conditions. Objectives: to evaluate the prevalence of diaphragmatic dysfunction (DD) during AECOPD, and its impact on NIV outcome. Setting: Department of Chest, Respiratory intensive care unit (ICU), Beni-Suef University Hospital. Methods: a prospective observational study which was conducted on 41 adult patients with acute exacerbation of chronic obstructive pulmonary disease who were admitted to respiratory ICU of chest department Beni-Suef University hospital for NIV. The cases underwent diaphragmatic assessment by bedside diaphragmatic ultrasound. Diaphragmatic thickness fraction (DTF) was calculated from the following formula: (Diaphragmatic thickness at end inspiration – Diaphragmatic Thickness at end expiration) / Diaphragmatic Thickness at end expiration. NIV outcomes (failure and success groups) was analyzed to find a cutoff point of DTF to predict success of NIV. Results: The prevalence of diaphragmatic dysfunction in all studied patients was 18 patients (43.5%) out of 41 patients most of them were among NIV failure group [12 (70.5%) out of 17 patients]. The cut off point of DTF was below 0.306 to predict failure of NIV . with a P value 0.002. Conclusions : Assessment of DTF by diaphragm ultrasound in B-mode represents an easy to-obtain new index for prediction of success or failure of NIV in AECOPD patients needing NIV.
摘要:背景:无创通气(NIV)目前被视为慢性阻塞性肺疾病急性加重期呼吸性酸中毒(AECOPD)患者的一线治疗方法。因此,识别无创通气失败的预测因素可以帮助临床医生发现更有可能出现负面结果的患者。其中一个因素是膈功能障碍(DD)。虽然测量横膈膜压力是评估横膈膜功能的金标准,但床边横膈膜超声检查(US)能够在几种临床情况下识别(DD)。目的:评估AECOPD期间膈肌功能障碍(DD)的患病率及其对NIV结果的影响。单位:贝尼苏夫大学附属医院呼吸科重症监护病房(ICU)。方法:对贝尼苏夫大学医院胸科呼吸ICU收治的41例慢性阻塞性肺疾病急性加重期患者进行前瞻性观察研究。患者行床边横膈膜超声检查。膈肌厚度分数(DTF)由以下公式计算:(吸气末膈肌厚度-呼气末膈肌厚度)/呼气末膈肌厚度。分析NIV结果(失败组和成功组)以寻找DTF的截断点来预测NIV的成功。结果:41例患者中膈功能障碍发生率为18例(43.5%),其中大部分为NIV失效组[17例患者中12例(70.5%)]。DTF的截断点小于0.306可预测NIV失效。P值为0.002。结论:b型膈超声评价DTF是预测AECOPD需用无创通气患者无创通气成功与否的一项容易获得的新指标。
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引用次数: 0
Survey of non-alcoholic steatohepatitis in non-diabetic Haemodialysis patients in Beni-Suef Governorate 贝尼苏韦省非糖尿病血液透析患者非酒精性脂肪性肝炎调查
Pub Date : 2022-10-01 DOI: 10.21608/ejmr.2022.271021
Ahmed Ibrahima, M. Salem, M. Abdel-Rahman, Tamer Mohamed
: Background : Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are global health issues all over the world, affecting about30% (NAFLD), and15% (CKD) of general people. Even, with absence of other risk factors such as overweight, diabetes and hypertension, there is force correlation between NAFLD and CKD. Objective: The target of our study is to detect the incidence of non-alcoholic steatohepatitis between non-diabetic hemodialysis patients by measuring Controlled Attenuation Parameter (CAP) using transient elastography (TE) (Fibroscan®). Methodology: This was a cross sectional study in Beni-Suef governorate, including 1000 hemodialysis non-diabetic ESRD patients from different hemodialysis units from all the central hospitals in Beni-Suef governorate. Results : According to CAP (dB/M) there were 503(50.3%) S0, 233(23.3%) S1, 100(10.0%) S1-S2, 67(6.7%) S2,10(1.0%) S2-S3 and 87(8.7%) S3. According to liver stiffness grades there were 508(50.8%) F0, 280(28.0%) F1, 57(5.7%) F2,95(9.5%) F3 and 60(6.0%) F4. There were 508(50.8%) F0 and 492(49.2%) F1:F4 with mean 6.14 (± 3.90SD) and range (2.0 – 19.90). Conclusions: In this study we concluded that there is a high incidence of NAFLD among non-diabetic patients on regular Hemodialysis in Beni-Suef governorate, significantly correlated with increasing degree of liver stiffness.
背景:非酒精性脂肪性肝病(NAFLD)和慢性肾脏疾病(CKD)是全球范围内的全球性健康问题,约占总人口的30% (NAFLD)和15% (CKD)。即使没有其他危险因素,如超重、糖尿病和高血压,NAFLD和CKD之间也存在强相关性。目的:本研究的目的是通过瞬时弹性成像(TE) (Fibroscan®)测量控制衰减参数(CAP)来检测非糖尿病血液透析患者之间非酒精性脂肪性肝炎的发生率。方法:这是一项在贝尼-苏韦夫省进行的横断面研究,包括来自贝尼-苏韦夫省所有中心医院不同血液透析单位的1000名血液透析非糖尿病ESRD患者。结果:根据CAP (dB/M),有503例(50.3%)S0, 233例(23.3%)S1, 100例(10.0%)S1-S2, 67例(6.7%)S2,10例(1.0%)S2-S3和87例(8.7%)S3。肝硬度分级为F0 508只(50.8%),F1 280只(28.0%),F2 57只(5.7%),F3 95只(9.5%),F4 60只(6.0%)。F0 508例(50.8%),F1:F4 492例(49.2%),平均6.14(±3.90SD),范围为2.0 ~ 19.90。结论:在本研究中,我们得出结论,Beni-Suef省定期血液透析的非糖尿病患者NAFLD发病率高,与肝脏僵硬程度增加显著相关。
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引用次数: 0
Comparison of Ranibizumab alone versus Ranibizumab with Targeted Retinal Laser for Branch Retinal Vein Occlusion with Macular Oedema. 雷尼单抗单用与雷尼单抗联合靶向视网膜激光治疗视网膜分支静脉闭塞伴黄斑水肿的比较
Pub Date : 2022-10-01 DOI: 10.21608/ejmr.2021.98694.1142
Mohamed Abdelmoneem, Mohamed Sayed Saif, Mohamed Abd Elkalek
: Background: Retinal vein occlusion is the second most common retinal vascular disease after diabetic retinopathy. Branch retinal venous occlusion (BRVO) occurs the occlusion of one of the branches of the retinal vein. The occlusion occurs mostly at arteriovenous crossing and more frequent in upper temporal retinal veins. Patients and Methods: In the current study, randomized control study was conducted on 2 groups divided into 27 eyes (Ranibizumab alone), 27 eyes (Ranibizumab and Targeted retinal laser). Results: The BRVO is investigated by FFA and OCT-Macula and macular edema is measured by OCT-Macula. And the current result shows highly statistically significant improvement in visual acuity and reducing macular edema (decrease foveal thickness)with P value <0.001 in Ranibizumab alone compared with Ranibizumab and retinal laser.
背景:视网膜静脉阻塞是仅次于糖尿病视网膜病变的第二常见的视网膜血管疾病。视网膜静脉分支闭塞(BRVO)发生在视网膜静脉分支之一的闭塞。闭塞多发生在动静脉交叉处,多见于颞上视网膜静脉。患者和方法:本研究采用随机对照研究,分为2组,分别为27只眼(单独使用雷尼单抗)和27只眼(雷尼单抗联合靶向视网膜激光)。结果:FFA和OCT-Macula检测BRVO, OCT-Macula检测黄斑水肿。目前的结果显示,与雷尼单抗联合视网膜激光治疗相比,单用雷尼单抗治疗在改善视力和减少黄斑水肿(减少中央窝厚度)方面具有高度统计学意义,P值<0.001。
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引用次数: 0
The use of three chip high definition camera with modular enhancement system with white light cystoscopy during transurethral resection of bladder tumours. Does it improve carcinoma in situ detection? 经尿道膀胱肿瘤切除术中应用三芯片高清摄像头与模块化增强系统结合白光膀胱镜。它能提高原位癌的检出率吗?
Pub Date : 2022-10-01 DOI: 10.21608/ejmr.2022.266078
A. Abdelbary, Ossama Mohamad, A. Abd El Latif, Almotasem Bellah Adel, Akram A. Elmarakbi
: The goal of our study is to assess if the use of Storz professional image enhancement system (SPIES) improve carcinoma in situ (CIS) detection. We conducted a prospective study on 35 patients of both sexes who have fulfilled the inclusion criteria from December 2019 to May 2020. Preoperatively, we collected urine samples from all patients amenable for cystoscopy for urine analysis and urine cytology. Contrast enhanced abdomen and pelvic computerized tomography (CT) was done for all patients. Under spinal anaesthesia white light cystoscopy (WLC) was done first, then SPIES camera was used by the same operator to detect any other suspicious lesions. TURBT was done for all lesions and specimens were sent for histopathology assessment. Our results showed that there was statistically significant difference between the SPIES and WLC regarding the number of lesions detected, as the total number of lesions detected by the SPIES was 37 lesions, three of these lesions were CIS, but the WLC detected only 27 lesions, no CIS was detected by WLC ( p value 0.001). Pathological recurrence was confirmed in 6/35 (17.1%) patients at 3 months follow up.
我们研究的目的是评估使用Storz专业图像增强系统(SPIES)是否能提高原位癌(CIS)的检测。我们在2019年12月至2020年5月期间对35名符合纳入标准的男女患者进行了前瞻性研究。术前,我们收集了所有适合膀胱镜检查的患者的尿液样本进行尿液分析和尿液细胞学检查。所有患者均行腹部和骨盆CT增强扫描。脊髓麻醉下先行白光膀胱镜检查(WLC),再由同一操作人员使用SPIES相机检查其他可疑病变。所有病变均行TURBT检查,并送标本进行组织病理学评估。我们的研究结果显示,SPIES和WLC在检测病变数量上有统计学差异,SPIES检测到的病变总数为37个,其中3个为CIS,而WLC仅检测到27个病变,WLC未检测到CIS (p值0.001)。随访3个月,6/35例(17.1%)患者确诊病理性复发。
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引用次数: 0
Circular Ribonucleic Acid Expression in Patient with Acne 环状核糖核酸在痤疮患者中的表达
Pub Date : 2022-10-01 DOI: 10.21608/ejmr.2021.88645.1101
A. El-Taweel, Abd-Elaziz Al-Refae, Mona Abd-Ellateef, R. Mohammad
: Background: Acne is a common chronic skin disease with a multifactorial aetiology and pathogenesis. Recently, circular RNAs (circRNAs) have been identified as a key factor in regulating gene expression through circRNA–miRNA–mRNA networks in many biological processes and human diseases. However, the circRNAs expression in patients with acne is still unknown, Aim and Objectives: To evaluate circular RNA Expression in Patient with Acne and to correlate its level with acne severity, Subjects and Methods: this was a case control study was conducted at conducted at Dermatology outpatient clinic at Beni-Suef University hospital including 40 with acne vulgaris and 40 normal as control. The duration of the study ranged from 6 months, Results: The mean CIRCULAR RNA 0001073 for cases group was 0.47 (±0.3 SD) with range (0.11-1.2) and that the mean CIRCULAR RNA 0001073 for control group was 1.03 (±0.1 SD) with range (0.95-1.2), and There was high statistically significant difference between the studied groups as regard CIRCULAR RNA 0001073. Conclusion: This study firstly showed that circRNAs were differentially expressed in severe acne and suggested that circRNAs could be used as a potential biomarker for the drug targets of acne.
背景:痤疮是一种常见的慢性皮肤病,其病因和发病机制是多因素的。近年来,环状rna (circRNAs)已被确定为在许多生物过程和人类疾病中通过circRNA-miRNA-mRNA网络调节基因表达的关键因素。目的和目的:为了评估痤疮患者的环状RNA表达水平及其与痤疮严重程度的相关性,受试者和方法:本研究是在贝尼-苏夫大学医院皮肤科门诊进行的一项病例对照研究,其中包括40名普通痤疮患者和40名正常痤疮患者作为对照。研究持续时间为6个月,结果:病例组平均CIRCULAR RNA 0001073为0.47(±0.3 SD),范围为0.11-1.2;对照组平均CIRCULAR RNA 0001073为1.03(±0.1 SD),范围为0.95-1.2,两组间CIRCULAR RNA 0001073的差异有较高的统计学意义。结论:本研究首次发现circRNAs在重度痤疮中存在差异表达,提示circRNAs可作为痤疮药物靶点的潜在生物标志物。
{"title":"Circular Ribonucleic Acid Expression in Patient with Acne","authors":"A. El-Taweel, Abd-Elaziz Al-Refae, Mona Abd-Ellateef, R. Mohammad","doi":"10.21608/ejmr.2021.88645.1101","DOIUrl":"https://doi.org/10.21608/ejmr.2021.88645.1101","url":null,"abstract":": Background: Acne is a common chronic skin disease with a multifactorial aetiology and pathogenesis. Recently, circular RNAs (circRNAs) have been identified as a key factor in regulating gene expression through circRNA–miRNA–mRNA networks in many biological processes and human diseases. However, the circRNAs expression in patients with acne is still unknown, Aim and Objectives: To evaluate circular RNA Expression in Patient with Acne and to correlate its level with acne severity, Subjects and Methods: this was a case control study was conducted at conducted at Dermatology outpatient clinic at Beni-Suef University hospital including 40 with acne vulgaris and 40 normal as control. The duration of the study ranged from 6 months, Results: The mean CIRCULAR RNA 0001073 for cases group was 0.47 (±0.3 SD) with range (0.11-1.2) and that the mean CIRCULAR RNA 0001073 for control group was 1.03 (±0.1 SD) with range (0.95-1.2), and There was high statistically significant difference between the studied groups as regard CIRCULAR RNA 0001073. Conclusion: This study firstly showed that circRNAs were differentially expressed in severe acne and suggested that circRNAs could be used as a potential biomarker for the drug targets of acne.","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90877973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relation between Vitamin D Receptors Gene Polymorphism and Lupus Nephritis 维生素D受体基因多态性与狼疮性肾炎的关系
Pub Date : 2022-07-01 DOI: 10.21608/ejmr.2022.256658
Heba Mahmoud, Mahmoud B. Ahmed, Shaimaa Abd elkareem, Hanaa Rabie
: The goal of this study is to Correlate between Vitamin D receptor polymorphism (FOKI) and lupus nephritis. Eighty subjects were included in this study. They were divided into two groups as follows: Control group: consisted of twenty apparently healthy volunteers of comparable age and socioeconomic status to the patients group. Patients group: consisted of sixty patients with SLE. They were selected from the Internal Medicine departement and Rheumatology out patient clinic of Beni-suef University hospital. In this study, Regarding CBC changes ,The prevalence of thrombocytopenia and lymphopenia was significantly higher among SLE patients compared to our controls, However the prevalence of lymphopenia and leucopenia was significantly higher among SLE patients with GG genotype compared to SLE patients with AG and AA mutants ,Regarding liver function tests, The mean serum Albumin level was significantly lower among SLE patients compared to controls .Antinuclear antibody titre was significantly higher among SLE patients than controls ,Also Anti Ds DNA is represented in SLE patients in ahigh titre than healthy controls ,Furthermore, All SLE patients with GG genotypes had positive Anti Ds DNA( 100%) compared to SLE patients with AG ( 0,0) and AA ( 0,0) mutants. It is recommended to carry out further studies on FOKI gene polymorphisms in larger groups of patients and controls.
本研究的目的是探讨维生素D受体多态性(FOKI)与狼疮性肾炎的关系。本研究共纳入80名受试者。他们被分为两组:对照组:由20名年龄和社会经济地位与患者组相当的表面健康的志愿者组成。患者组:60例SLE患者。他们选自贝尼苏夫大学医院内科和风湿科门诊。在本研究中,关于CBC的变化,SLE患者的血小板减少症和淋巴细胞减少症的患病率明显高于我们的对照组,而GG基因型SLE患者的淋巴细胞减少症和白细胞减少症的患病率明显高于AG和AA突变型SLE患者。SLE患者的平均血清白蛋白水平明显低于对照组,SLE患者的抗核抗体滴度明显高于对照组,SLE患者的抗Ds DNA滴度也明显高于健康对照组,所有GG基因型SLE患者的抗Ds DNA阳性(100%)均高于AG(0,0)和AA(0,0)突变型SLE患者。建议在更大的患者和对照人群中开展FOKI基因多态性的进一步研究。
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引用次数: 0
Prognostic value of IL18 serum levels in COVID-19 Patients at Beni- Suef University Hospital 贝尼苏夫大学医院COVID-19患者血清il - 18水平的预后价值
Pub Date : 2022-07-01 DOI: 10.21608/ejmr.2022.259009
Nada El-Sagheer, A. Gomaa, Laila A Alsharaway, M. Abdel-Aziz
{"title":"Prognostic value of IL18 serum levels in COVID-19 Patients at Beni- Suef University Hospital","authors":"Nada El-Sagheer, A. Gomaa, Laila A Alsharaway, M. Abdel-Aziz","doi":"10.21608/ejmr.2022.259009","DOIUrl":"https://doi.org/10.21608/ejmr.2022.259009","url":null,"abstract":"","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76373397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal Depression and Its Relation to Mental Health Problems in children 母亲抑郁及其与儿童心理健康问题的关系
Pub Date : 2022-07-01 DOI: 10.21608/ejmr.2022.251449
Asmaa Awad, Maha Ahmed, H. Zaki, M. Salem
: This work aimed at determining the relation between maternal depression and emotional & behavioral problems in children aged 1 ½ to 5 y in the Egyptian pediatric population. This exploratory cross-sectional study was conducted at the pediatric outpatient clinic, at Beni- Suef University Hospital, over a period twenty months from September 2016 to May 2018. The total number of participants who were at the first visit was 164 participants, they completed all the questionnaires, but 20 participants didn’t attend the next visit after two weeks from the first visit, so the total number that participated in the two visits was 143 participants .The current study reported that self-report screening for maternal depression is feasible in primary care settings. In our study the results showed that a large numbers of mothers have depression about 87.8 % of the participant mothers have depression in the first and the second interview. In conclusion, the current study revealed that maternal depression was significantly related to higher levels of internalizing, externalizing, and general psychopathology.
本研究旨在确定埃及1岁半至5岁儿童的母亲抑郁与情绪和行为问题之间的关系。本探索性横断面研究于2016年9月至2018年5月期间在Beni- Suef大学医院的儿科门诊进行。在第一次访问的参与者总数为164人,他们完成了所有的问卷,但20名参与者在第一次访问的两周后没有参加第二次访问,因此参加两次访问的总人数为143人。目前的研究报告自我报告筛查产妇抑郁症在初级保健机构是可行的。在我们的研究中,结果显示大量的母亲患有抑郁症,在第一次和第二次访谈中,约有87.8%的参与者母亲患有抑郁症。综上所述,本研究表明,母亲抑郁与较高水平的内在化、外在化和一般精神病理显著相关。
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引用次数: 0
Prevalence of hypocalcemia in asymptomatic pregnant females in Upper Egypt 上埃及无症状孕妇低钙血症的患病率
Pub Date : 2022-07-01 DOI: 10.21608/ejmr.2022.251656
Asmaa Mohamed Abdel- Aty, M. Youssef, Y. Mohamed
: The goal of this study is to investigate the levels of serum calcium in asymptomatic pregnant women and measuring the prevalence of hypocalcaemia. Healthy pregnant women (n=500) were enrolled consecutively, with singleton pregnancy, in first trimester with the mean gestational age (9.5 ±1) weeks of gestation. Serum Total and Ionized calcium were measured to all women in the study. The prevalence of hypocalcaemia was measured. Nearly two thirds of women (337) had hypocalcaemia (67.4%), Only 163 had normal calcium levels" serum calcium level of 8.6 mg/dL or above". The prevalence of hypocalcaemia was more in young aged women as about two-thirds (64.8%) were in the age group 20 to less than 30 years, with mean age 23.9 ±4.6 years. Also the prevalence of hypocalcaemia was high in parity less than 2, with statistically significant p-value (0.034). No determinants (education, dietary intake of Ca +2 , weight, height, BMI, and Hb levels) found in our study to be in correlation with the high incidence of hypocalcaemia.
本研究的目的是调查无症状孕妇的血钙水平,并测量低钙血症的患病率。连续纳入健康孕妇(n=500),均为单胎妊娠,孕早期平均胎龄(9.5±1)周。对研究中所有女性的血清总钙和离子钙进行了测量。测量低钙血症的发生率。近三分之二的妇女(337人)患有低钙血症(67.4%),只有163人的钙水平正常,即血清钙水平在8.6 mg/dL或以上。低钙血症在年轻女性中患病率更高,约三分之二(64.8%)的患者年龄在20至30岁以下,平均年龄23.9±4.6岁。胎次小于2胎的低钙血症发生率较高,p值(0.034)有统计学意义。在我们的研究中,没有发现任何决定因素(教育程度、饮食中钙+2的摄入量、体重、身高、BMI和Hb水平)与低钙血症的高发相关。
{"title":"Prevalence of hypocalcemia in asymptomatic pregnant females in Upper Egypt","authors":"Asmaa Mohamed Abdel- Aty, M. Youssef, Y. Mohamed","doi":"10.21608/ejmr.2022.251656","DOIUrl":"https://doi.org/10.21608/ejmr.2022.251656","url":null,"abstract":": The goal of this study is to investigate the levels of serum calcium in asymptomatic pregnant women and measuring the prevalence of hypocalcaemia. Healthy pregnant women (n=500) were enrolled consecutively, with singleton pregnancy, in first trimester with the mean gestational age (9.5 ±1) weeks of gestation. Serum Total and Ionized calcium were measured to all women in the study. The prevalence of hypocalcaemia was measured. Nearly two thirds of women (337) had hypocalcaemia (67.4%), Only 163 had normal calcium levels\" serum calcium level of 8.6 mg/dL or above\". The prevalence of hypocalcaemia was more in young aged women as about two-thirds (64.8%) were in the age group 20 to less than 30 years, with mean age 23.9 ±4.6 years. Also the prevalence of hypocalcaemia was high in parity less than 2, with statistically significant p-value (0.034). No determinants (education, dietary intake of Ca +2 , weight, height, BMI, and Hb levels) found in our study to be in correlation with the high incidence of hypocalcaemia.","PeriodicalId":11524,"journal":{"name":"Egyptian Journal of Medical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72801771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Egyptian Journal of Medical Research
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