Epilepsy & Behavior最新文献

{"title":"Postpartum depression and mother-infant bonding in women with epilepsy: A case-control study","authors":"Rehab Magdy ,&nbsp;Nirmeen A. Kishk ,&nbsp;Mennat-Allah Tarek ,&nbsp;Manal Moussa ,&nbsp;Marwa M. Zein ,&nbsp;Mohamed Khodery ,&nbsp;Salsabil Abo Al-Azayem","doi":"10.1016/j.yebeh.2024.110213","DOIUrl":"10.1016/j.yebeh.2024.110213","url":null,"abstract":"<div><h3>Background &amp; Objectives</h3><div>Postpartum depression is a debilitating mental health condition that consequently can negatively impact the mother/infant unit. This study aimed to screen for postpartum depression among women with epilepsy (WWE) versus healthy women and its consequences on establishing a proper mother-infant bonding.</div></div><div><h3>Methods</h3><div>A group of WWE (n = 102) and a control group of healthy women (n = 119) were evaluated 4–6 weeks postpartum. The Edinburgh Postnatal Depression Scale (EPDS) and the Postpartum Bonding Questionnaire (PBQ) were used.</div></div><div><h3>Results</h3><div>The median scores of EPDS did not significantly differ between WWE and the control group (P = 0.077). The median scores of infant-focused anxiety of PBQ were significantly lower in WWE than in the control group, while the median scores of risk of abuse were significantly higher in the former than in the latter group. Scores of EPDS and PBQ didn’t significantly differ between groups of different seizure types, etiologies, and ASMs regimens. However, the EPDS scores were significantly higher in WWE, who experienced seizure exacerbation, than in others (<em>P</em> = 0.049). Also, EPDS scores were significantly correlated with PBQ scores. By linear regression analysis, the only independent predictor of EPDS score was seizure exacerbation during pregnancy.</div></div><div><h3>Conclusion</h3><div>The current postpartum screening report revealed that WWE are not at an increased risk of postpartum depression than healthy women. However, WWE who experience seizure exacerbations during their pregnancy need to be cautiously screened for postpartum depression, which may negatively impact mother-infant bonding. Strenuous efforts should be made to improve the mental health services for those women.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"163 ","pages":"Article 110213"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors affecting quality of life in children with epilepsy and their caregivers: A secondary analysis of a cross-sectional online survey in Japan","authors":"Shin Okazaki ,&nbsp;Takuya Kumagai ,&nbsp;Shinichi Nishiuma ,&nbsp;Katsuhiko Iwasaki ,&nbsp;Kazuaki Yamamoto ,&nbsp;Kinya Kokubo ,&nbsp;Hiroomi Hayashi ,&nbsp;Eiji Nakagawa","doi":"10.1016/j.yebeh.2024.110227","DOIUrl":"10.1016/j.yebeh.2024.110227","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate the quality of life (QOL) in children with epilepsy and their caregivers, as well as the caregiver burden, through a secondary analysis of a cross-sectional online survey in Japan.</div></div><div><h3>Methods</h3><div>Eligible participants were caregivers of children (aged &lt; 18 years) diagnosed with epilepsy. Children’s QOL was measured using the daily living subset of the Japanese version of the Quality of Life in Children with Epilepsy (QOLCE-Js52). Caregiver QOL and burden were measured using the physical component summary (PCS) and mental component summary (MCS) of the Short Form-8 (SF-8) and the short Japanese version of the Zarit Caregiver Burden Interview (J-ZBI_8).</div></div><div><h3>Results</h3><div>Between March 2023 and May 2023, 1,147 caregivers completed the survey. Most caregivers (n = 1,144, 99.7 %) were parents. The mean (standard deviation [SD]) QOLCE-Js52 score was 68.3 (14.2). The mean (SD) scores of the PCS and MCS of the SF-8 were 46.5 (4.5) and 43.7 (5.1), respectively, which were significantly lower than those of the general Japanese population (p &lt; 0.001 for both means). The mean (SD) J-ZBI_8 score was 4.9 (7.1), with 13.2 % of caregivers scoring at least 13, a predictor of depression. Multivariable regression analysis showed that disability was a significant risk factor for lower QOL and increased caregiver burden (p &lt; 0.001). Frequent seizures, emergency transportation, and longer epilepsy duration were associated with poorer QOL in children and caregivers.</div></div><div><h3>Conclusion</h3><div>Risk factors, such as emergency transport, may be mitigated by rescue medication in non-hospital settings.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"163 ","pages":"Article 110227"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can people with epilepsy trust AI chatbots for information on physical exercise?","authors":"Rizia Rocha-Silva ,&nbsp;Bráulio Evangelista de Lima ,&nbsp;Thalles Guilarducci Costa ,&nbsp;Naiane Silva Morais ,&nbsp;Geovana José ,&nbsp;Douglas Farias Cordeiro ,&nbsp;Alexandre Aparecido de Almeida ,&nbsp;Glauber Menezes Lopim ,&nbsp;Ricardo Borges Viana ,&nbsp;Bolivar Saldanha Sousa ,&nbsp;Diego Basile Colugnati ,&nbsp;Rodrigo Luiz Vancini ,&nbsp;Marília Santos Andrade ,&nbsp;Katja Weiss ,&nbsp;Beat Knechtle ,&nbsp;Ricardo Mario Arida ,&nbsp;Claudio Andre Barbosa de Lira","doi":"10.1016/j.yebeh.2024.110193","DOIUrl":"10.1016/j.yebeh.2024.110193","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aims to evaluate the similarity, readability, and alignment with current scientific knowledge of responses from AI-based chatbots to common questions about epilepsy and physical exercise.</div></div><div><h3>Methods</h3><div>Four AI chatbots (ChatGPT-3.5,ChatGPT 4, Google Gemini, and Microsoft Copilot) were evaluated. Fourteen questions on epilepsy and physical exercise were designed to compare the platforms. Lexical similarity, response patterns, and thematic content were analyzed. Readability was measured using the Flesch Reading Ease and Flesch–Kincaid Grade Level scores. Seven experts rated the quality of responses on a Likert scale from “very poor” to “very good.”</div></div><div><h3>Results</h3><div>The responses showed lexical similarity, with approaches to physical exercise ranging from conservative to holistic. Microsoft Copilot scored the highest on the Flesch Reading Ease scale (48.42 ± 13.71), while ChatGPT-3.5 scored the lowest (23.84 ± 8.19). All responses were generally rated as difficult to read. Quality ratings ranged from “Good” to “Acceptable,” with ChatGPT 4 being the preferred platform, chosen by 48.98 % of reviewers.</div></div><div><h3>Conclusion</h3><div>The findings highlight the potential of AI chatbots as useful sources of information on epilepsy and physical exercise. However, simplifying language and tailoring content to user’s needs is essential to enhance their effectiveness.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"163 ","pages":"Article 110193"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the lived experiences of people living with epilepsy: Oral history assessment in the Shai Osudoku and Ningo Prampram districts, Ghana","authors":"Sabina Asiamah ,&nbsp;Phyllis Dako Gyeke ,&nbsp;Emmanuel Kwame Darkwa ,&nbsp;Sloan Mahone ,&nbsp;John Williams ,&nbsp;Albert Akpalu ,&nbsp;Charles R. Newton ,&nbsp;Cynthia Sottie ,&nbsp;Patrick Adjei","doi":"10.1016/j.yebeh.2024.110211","DOIUrl":"10.1016/j.yebeh.2024.110211","url":null,"abstract":"<div><h3>Introduction</h3><div>Epilepsy is a prevalent neurological condition globally, especially in Sub-Saharan Africa. In Ghana, it is one of the top five causes of premature death and disability, impacting children’s neurological development and learning outcomes. Although 25% of epilepsy cases are preventable, many go undiagnosed and untreated. People with epilepsy face social stigma and rejection, hindering their ability to seek healthcare, employment, and social interactions, which worsens their self-esteem and social integration.</div></div><div><h3>Purposes</h3><div>The study aims to address the critical gaps in understanding and supporting people living with epilepsy (PLWE), through recording and analysing their experiences, and seeks to inform policy and practice, finally contributing to improve healthcare delivery, reduce stigma, and enhance support systems for PLWE.</div></div><div><h3>Methods</h3><div>A qualitative research design was employed for the study. Oral histories (OHs) were conducted with ten PLWE. These interviews encourage interviewees to focus on the life stories and experiences that mean the most to them and can be shared in their own words The interview questions were constructed in English and conducted in English, Twi, Ga and Dangme.</div></div><div><h3>Results</h3><div>The residents of Shai Osudoku and Ningo Prampram hold robust religious convictions and engage in profound spiritual practices as is the case throughout Ghana. When faced with health challenges, the PLWE and their caregivers often seek assistance from faith-based spiritual healers, including pastors or religious leaders, as their initial source of support and healing. These healers provide care by offering prayers, spiritual counselling, and incorporating various religious rituals into their healing practices. It was revealed that many PLWE, caregivers and community members perceived epilepsy differently. Some perceived it as a spiritual or demonic disease. Whilst others attributed to curse and disease of witches, idols, or gods. However, the healthcare practitioners perceived epilepsy as a medical condition. Also, it was found that individuals faced challenges, such as stigma and discrimination.</div></div><div><h3>Conclusion</h3><div>It is recommended that public education on epilepsy be intensified. Furthermore, there is the need to ensure that PLWE have access to improved healthcare to increase their quality of life.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"163 ","pages":"Article 110211"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors in the development of refractory status epilepticus in status epilepticus patients","authors":"Oruç Şahin,&nbsp;Muzaffer Güneş","doi":"10.1016/j.yebeh.2024.110232","DOIUrl":"10.1016/j.yebeh.2024.110232","url":null,"abstract":"<div><h3>Objectives</h3><div>Status epilepticus (SE) is a severe neurological condition associated with a poor prognosis. Refractory status epilepticus (RSE) is a treatment-resistant form of SE with an even worse prognosis. The exact mechanisms underlying the development of RSE are not fully understood. The aim of this study was to investigate the factors contributing to the development of RSE in SE patients and to identify predictors of RSE occurrence.</div></div><div><h3>Methods</h3><div>This retrospective study was conducted on patients diagnosed with SE and RSE between 2014 and 2024. Demographic information, comorbid conditions, and blood sample data of the patients were recorded for statistical analysis. The statistical analyses used included the Mann-Whitney <em>U</em> test, Chi-square test, Fisher’s exact test, ROC curve analysis, and logistic regression.</div></div><div><h3>Results</h3><div>A total of 82 SE patients were included in the study. Of these, 44 were non-RSE patients (control group), and 38 were RSE patients. Significant differences were observed between the groups in terms of median age (p = 0.001), blood glucose level (p = 0.023), pan-immune inflammation value (PIV) (p = 0.002), Monocyte/Lymphocyte Ratio (MLR) (p = 0.009), Neutrophil/Albumin Ratio (NAR) (p = 0.003), Systemic Immune Inflammation Index (SII) (p = 0.013), Eosinophil/Lymphocyte Ratio (ELR) (p = 0.016), Eosinophil/Neutrophil Ratio (ENR) (p = 0.006), and Eosinophil/Monocyte Ratio (EMR) (p = 0.002). The multivariate logistic regression model identified the presence of arterial hypertension as the only factor significantly associated with the development of RSE (p &lt; 0.001). In the ROC curve analysis, PIV (AUC = 0.696) and NAR (AUC = 0.689) were found to be predictive factors for RSE.</div></div><div><h3>Conclusions</h3><div>The findings obtained in the current study suggest that systemic inflammation and arterial hypertension may be associated with the progression of SE to RSE. Further research is needed to confirm these findings and integrate them into routine clinical practice.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"163 ","pages":"Article 110232"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reconsidering the ethics of provocation techniques for Psychogenic Non-Epileptic Attacks and proposed ethical guidelines for use","authors":"James Dolbow ,&nbsp;Matt Deaton ,&nbsp;Marshall Kirsch ,&nbsp;Jeanne Lackamp ,&nbsp;Jonathan Zande","doi":"10.1016/j.yebeh.2024.110184","DOIUrl":"10.1016/j.yebeh.2024.110184","url":null,"abstract":"<div><div>Patients with psychogenic non-epileptic attacks (PNEA) are subject to considerable direct and indirect comorbid psycho-socio-economic impact from their condition. Fortunately, diagnosis and treatment of PNEA has shown to be both medically effective and cost-efficient, ultimately improving PNEA symptoms, mental health, quality of life, and healthcare resource utilization. Though provocation techniques for PNEA have proven highly effective in diagnosing and providing expedited treatment to these patients, they have recently begun to fall out of favor due to ethical concerns about their use. Today, over one-fourth of epilepsy monitoring units do not utilize PNEA provocation techniques in those suspected of the condition. Of the monitoring units that do, less than 10% have an established protocol, and only 20% reported patient consent. The ethics and implications of the methods of diagnosing PNEA have been debated for decades. Specifically, the ethicality of attempting to provoke PNEA episodes using the proven effective methods of suggestion, nocebo, and other techniques have often left clinicians and medical ethicists offering opposing views. Here we review the personal and societal costs of PNEA, the efficacy of these provocation techniques, and the ethical considerations regarding their use, with specific emphasis on the importance of how these techniques are described to patients, as to both ensure informed consent and removed deception. Additionally, addressing these concerns, we propose ethical guidelines for the use of provocation techniques for the diagnosis of PNEA, concluding that such techniques can be ethically applied when certain conditions are met.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"163 ","pages":"Article 110184"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and correlates of alexithymia in drug-resistant epilepsies","authors":"O. Paradas ,&nbsp;S. Pradier ,&nbsp;M. Decilap ,&nbsp;A. Viaud ,&nbsp;L. Chibani ,&nbsp;M. De-Montaudouin ,&nbsp;A. Gradel ,&nbsp;V. Michel ,&nbsp;J. Aupy","doi":"10.1016/j.yebeh.2024.110222","DOIUrl":"10.1016/j.yebeh.2024.110222","url":null,"abstract":"<div><h3>Introduction</h3><div>Alexithymia, characterized by difficulty identifying and expressing emotions, is commonly observed in individuals with psychiatric and neurological disorders. However, its prevalence in patients with epilepsy (PWE), particularly in those with drug-resistant epilepsy (DRE), remains under-researched. This study investigates the prevalence of alexithymia in patients with DRE and explores its associated factors.</div></div><div><h3>Methods</h3><div>We conducted a retrospective observational study of 118 adult patients with focal DRE undergoing presurgical evaluation at Bordeaux University Hospital. Alexithymia was assessed using the Toronto Alexithymia Scale-20 (TAS-20), while psychiatric symptoms were evaluated with validated scales. Data on demographic characteristics, epilepsy duration, seizure frequency, antiepileptic drug use, and localization of the epileptogenic zone (EZ) were collected and analyzed using logistic regression models.</div></div><div><h3>Results</h3><div>Alexithymia was identified in 40.7 % of patients. Depression and anxiety were significantly associated with alexithymia (p &lt; 0.01), whereas no correlation was observed between alexithymia and the localization or lateralization of the EZ.</div></div><div><h3>Discussion</h3><div>These findings suggest that alexithymia is prevalent among patients with DRE, with significant associations to depression and anxiety. The high prevalence of affective symptoms underscores the importance of early identification and intervention for alexithymia to improve outcomes in patients with DRE.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"163 ","pages":"Article 110222"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding teachers’ perspectives on students with epilepsy in Germany: A survey examining knowledge, experience, and affective, cognitive, and behavioral attitudes to inform teacher training","authors":"Pawel R. Kulawiak ,&nbsp;Nadine Poltz ,&nbsp;Jannis Bosch ,&nbsp;Mona Dreesmann","doi":"10.1016/j.yebeh.2024.110157","DOIUrl":"10.1016/j.yebeh.2024.110157","url":null,"abstract":"<div><div>The comprehensive teacher survey (<em>N</em> = 210 teachers), conducted in Germany, focused on a broad range of student needs (medical, instructional, and emotional), and captured teachers’ knowledge about epilepsy and experiences with students with epilepsy (SWE), alongside multiple attitudes towards SWE. Results reveal gaps in teachers’ understanding of appropriate responses to seizures, exemplified by 33 % believing an object should be put into the mouth during a seizure. Misconceptions about the risks of physical activity for SWE are prevalent among teachers (6.3–10.6 %). Misbeliefs and misconceptions about learning difficulties and deviant behavior of SWE are rare (0.5–3.4 %) and only a small subset of teachers (2.9 %) recommends special education schooling for SWE. The results highlight mixed feelings and thoughts (affective and cognitive attitudes), including negative emotions (45.5 %–66.7 %) and insecurities (25.1–50.5 %) about supervising SWE during activities. Some teachers (7.7–20.4 %) are inclined, with safety concerns in mind, to exclude SWE from activities (behavioral intention). Not all teachers exhibit sufficient confidence in seizure first aid (10.5–31.4 %), seizure-specific classroom management (27.3–47.8 %), and emotional support skills (10–28 %). These different attitude traits were identified through exploratory factor analysis. Knowledge about epilepsy and experiences with SWE are linked to favorable attitudes towards SWE, with correlations ranging from −0.27 to 0.19 for knowledge and from −0.37 to 0.26 for experiences (negative correlations with negative emotions and insecurities, and positive correlations with confidence in skills). Equipping teachers to handle both the medical and psychosocial aspects of epilepsy is crucial for ensuring the well-being of SWE at school.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"163 ","pages":"Article 110157"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Penosissima, y rigorosa enfermedad” (Most Troublesome and rigorous disease): An analysis of the first medical-moral treatise on epilepsy in Latin America","authors":"Jaime Carrizosa-Moog","doi":"10.1016/j.yebeh.2024.110243","DOIUrl":"10.1016/j.yebeh.2024.110243","url":null,"abstract":"<div><h3>Introduction</h3><div>The influence of the Enlightenment is evident with the mention of Herman Boerhave. The strong European influence draws attention with minimal expression of the social and medical concepts of pre-Colombian cultures such as the Aztec and Mayan.</div></div><div><h3>Methods</h3><div>A medical and cultural conceptual analysis of the text “Medical-moral report of the very painful, and rigorous disease of epilepsy” is carried out.</div></div><div><h3>Results</h3><div>The physicians of the Enlightenment managed to define epilepsy, classify its seizures, explain its causes and pathophysiology, as well as carry out a comprehensive approach. This biomedical concept complemented and coincided with theological explanations of epilepsy.</div></div><div><h3>Conclusion</h3><div>The Enlightenment was fundamental for a systematized development to explain epilepsy, which in some ways persists until today. The influence of the Aztec and Mayan cultures in this text is minimal.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"163 ","pages":"Article 110243"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and associated factors of caregiving burden among caregivers of adults with epilepsy in Malaysia – A cross-sectional study","authors":"Ismayanti Mohd Ismail ,&nbsp;Ching Soong Khoo ,&nbsp;Layan Ibrahim ,&nbsp;Marjorie Jia Yi Ong ,&nbsp;Hui Jan Tan ,&nbsp;Rozita Hod ,&nbsp;Azlin Baharudin ,&nbsp;Muhammad Samir Haziq Abd Rahman","doi":"10.1016/j.yebeh.2024.110244","DOIUrl":"10.1016/j.yebeh.2024.110244","url":null,"abstract":"<div><h3>Background</h3><div>There are still insufficient data on caregiver burden among caregivers of adult people with epilepsy (PWE), particularly in Malaysia. This study aims to explore the level of perceived caregiver burden among the informal caregivers caring for PWE, its predicting factors associated with caregiver burden, and the impact of this caregiver burden on their psychological health.</div></div><div><h3>Methods</h3><div>In this cross-sectional study, caregivers of adult PWE attending the neurology outpatient clinic at Hospital Canselor Tuanku Muhriz (HCTM) completed a comprehensive questionnaire comprising demographic data of participants and care recipients (adult PWE). Epilepsy-related data were obtained from the interview and medical records. Affiliate stigma among caregivers was assessed using Affiliate Stigma Scale (ASS), and psychological impacts were evaluated using Depression Anxiety Stress Scale 21 (DASS-21). The level of caregiver burden was evaluated with Zarit Burden Interview (ZBI).</div></div><div><h3>Results</h3><div>A total of 119 caregivers participated in the study, and 35.2 % of them reported mild to moderate burden. The factors most strongly associated with higher caregiver burden were female caregivers, needs for assistance in activities of daily living (ADL), frequent seizures, polypharmacy, and affiliate stigma among caregivers. A statistically significant positive correlation was seen between caregiver burden and psychological impacts of depression (<em>r</em> 0.522, <em>p</em> &lt; 0.001), anxiety (<em>r</em> 0.463, <em>p</em> &lt; 0.001), and stress (<em>r</em> 0.598, <em>p</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>This study demonstrated various degrees of caregiver burden among caregivers of adult PWE. A better understanding on the predictive factors and impacts on psychological health of caregivers are needed to provide suitable interventions including psychoeducation for the caregivers to alleviate their burden and subsequently improve the quality of caregiving.</div></div>","PeriodicalId":11847,"journal":{"name":"Epilepsy & Behavior","volume":"163 ","pages":"Article 110244"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}