Pub Date : 2024-11-01Epub Date: 2024-11-08DOI: 10.1289/EHP15224
Wendee Nicole
The integrated approach tackles a perfect storm of poverty, invasive rats, deforestation, and climate change that is contributing to the increase in bubonic plague cases.
这种综合方法解决了导致鼠疫病例增加的贫困、鼠类入侵、森林砍伐和气候变化等问题。
{"title":"Madagascar's Plague: One Health Research Aims to Slow Its Spread.","authors":"Wendee Nicole","doi":"10.1289/EHP15224","DOIUrl":"10.1289/EHP15224","url":null,"abstract":"<p><p>The integrated approach tackles a perfect storm of poverty, invasive rats, deforestation, and climate change that is contributing to the increase in bubonic plague cases.</p>","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":"132 11","pages":"112001"},"PeriodicalIF":12.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11548884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-25DOI: 10.1289/EHP16189
Carrie Arnold
High school students and teachers paired with researchers improved awareness, drinking water testing, and abatement in high-risk areas.
高中师生与研究人员结成对子，提高了高风险地区的认识、饮用水检测和减排能力。
{"title":"Education Fosters Action: Community Science Advances Arsenic Abatement in Maine and New Hampshire.","authors":"Carrie Arnold","doi":"10.1289/EHP16189","DOIUrl":"10.1289/EHP16189","url":null,"abstract":"<p><p>High school students and teachers paired with researchers improved awareness, drinking water testing, and abatement in high-risk areas.</p>","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":"132 11","pages":"114003"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-06DOI: 10.1289/EHP14334
Youran Tan, Stephanie M Eick, Anne L Dunlop, Dana Boyd Barr, Kaitlin R Taibl, Kyle Steenland, Kurunthachalam Kannan, Morgan Robinson, Che-Jung Chang, Parinya Panuwet, Volha Yakimavets, Carmen J Marsit, P Barry Ryan, Donghai Liang
<p><strong>Background: </strong>Longitudinal trends in per- and polyfluoroalkyl substances (PFAS) serum concentrations across pregnancy have not been thoroughly examined, despite evidence linking prenatal PFAS exposures with adverse birth outcomes.</p><p><strong>Objectives: </strong>We sought to characterize longitudinal PFAS concentrations across pregnancy and to examine the maternal-fetal transfer ratio among participants in a study of risk and protective factors for adverse birth outcomes among African Americans.</p><p><strong>Methods: </strong>In the Atlanta African American Maternal-Child cohort (2014-2020), we quantified serum concentrations of four PFAS in 376 participants and an additional eight PFAS in a subset of 301 participants during early (8-14 weeks gestation) and late pregnancy (24-30 weeks gestation). Among these, PFAS concentrations were also measured among 199 newborns with available dried blood spot (DBS) samples. We characterized the patterns, variability, and associations in PFAS concentrations at different time points across pregnancy using intraclass correlation coefficients (ICCs), maternal-newborn pairs transfer ratios, linear mixed effect models, and multivariable linear regression, adjusting for socioeconomic and prenatal predictors.</p><p><strong>Results: </strong>Perfluorohexane sulfonic acid (PFHxS), perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), and perfluorononanoic acid (PFNA) were detected in <math><mrow><mo>></mo><mn>95</mn><mo>%</mo></mrow></math> of maternal samples, with PFHxS and PFOS having the highest median concentrations. We observed high variability in PFAS concentrations across pregnancy time points (<math><mrow><mtext>ICC</mtext><mo>=</mo><mn>0.03</mn><mo>-</mo><mn>0.59</mn></mrow></math>). All median PFAS concentrations increased from early to late pregnancy, except for PFOA and N-methyl perfluorooctane sulfonamido acetic acid (NMFOSAA), which decreased [paired <math><mi>t</mi></math>-test for all PFAS <math><mrow><mi>p</mi><mo><</mo><mn>0.05</mn></mrow></math> except for PFOA and perfluorobutane sulfonic acid (PFBS)]. Prenatal serum PFAS were weakly to moderately correlated with newborn DBS PFAS (<math><mrow><mo>-</mo><mn>0.05</mn><mo><</mo><mtext>rho</mtext></mrow></math> <math><mrow><mo><</mo><mn>0.49</mn></mrow></math>). The median maternal-fetal PFAS transfer ratio was lower for PFAS with longer carbon chains. After adjusting for socioeconomic and prenatal predictors, in linear mixed effect models, the adjusted mean PFAS concentrations significantly increased during pregnancy, except for PFOA. In multivariable linear regression, PFAS concentrations in early pregnancy significantly predicted the PFAS concentrations in late pregnancy and in newborns.</p><p><strong>Discussion: </strong>We found that the concentrations of most PFAS increased during pregnancy, and the magnitude of variability differed by individual PFAS. Future studies are needed to understand the influence of
{"title":"A Prospective Analysis of Per- and Polyfluoroalkyl Substances from Early Pregnancy to Delivery in the Atlanta African American Maternal-Child Cohort.","authors":"Youran Tan, Stephanie M Eick, Anne L Dunlop, Dana Boyd Barr, Kaitlin R Taibl, Kyle Steenland, Kurunthachalam Kannan, Morgan Robinson, Che-Jung Chang, Parinya Panuwet, Volha Yakimavets, Carmen J Marsit, P Barry Ryan, Donghai Liang","doi":"10.1289/EHP14334","DOIUrl":"10.1289/EHP14334","url":null,"abstract":"<p><strong>Background: </strong>Longitudinal trends in per- and polyfluoroalkyl substances (PFAS) serum concentrations across pregnancy have not been thoroughly examined, despite evidence linking prenatal PFAS exposures with adverse birth outcomes.</p><p><strong>Objectives: </strong>We sought to characterize longitudinal PFAS concentrations across pregnancy and to examine the maternal-fetal transfer ratio among participants in a study of risk and protective factors for adverse birth outcomes among African Americans.</p><p><strong>Methods: </strong>In the Atlanta African American Maternal-Child cohort (2014-2020), we quantified serum concentrations of four PFAS in 376 participants and an additional eight PFAS in a subset of 301 participants during early (8-14 weeks gestation) and late pregnancy (24-30 weeks gestation). Among these, PFAS concentrations were also measured among 199 newborns with available dried blood spot (DBS) samples. We characterized the patterns, variability, and associations in PFAS concentrations at different time points across pregnancy using intraclass correlation coefficients (ICCs), maternal-newborn pairs transfer ratios, linear mixed effect models, and multivariable linear regression, adjusting for socioeconomic and prenatal predictors.</p><p><strong>Results: </strong>Perfluorohexane sulfonic acid (PFHxS), perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), and perfluorononanoic acid (PFNA) were detected in <math><mrow><mo>></mo><mn>95</mn><mo>%</mo></mrow></math> of maternal samples, with PFHxS and PFOS having the highest median concentrations. We observed high variability in PFAS concentrations across pregnancy time points (<math><mrow><mtext>ICC</mtext><mo>=</mo><mn>0.03</mn><mo>-</mo><mn>0.59</mn></mrow></math>). All median PFAS concentrations increased from early to late pregnancy, except for PFOA and N-methyl perfluorooctane sulfonamido acetic acid (NMFOSAA), which decreased [paired <math><mi>t</mi></math>-test for all PFAS <math><mrow><mi>p</mi><mo><</mo><mn>0.05</mn></mrow></math> except for PFOA and perfluorobutane sulfonic acid (PFBS)]. Prenatal serum PFAS were weakly to moderately correlated with newborn DBS PFAS (<math><mrow><mo>-</mo><mn>0.05</mn><mo><</mo><mtext>rho</mtext></mrow></math> <math><mrow><mo><</mo><mn>0.49</mn></mrow></math>). The median maternal-fetal PFAS transfer ratio was lower for PFAS with longer carbon chains. After adjusting for socioeconomic and prenatal predictors, in linear mixed effect models, the adjusted mean PFAS concentrations significantly increased during pregnancy, except for PFOA. In multivariable linear regression, PFAS concentrations in early pregnancy significantly predicted the PFAS concentrations in late pregnancy and in newborns.</p><p><strong>Discussion: </strong>We found that the concentrations of most PFAS increased during pregnancy, and the magnitude of variability differed by individual PFAS. Future studies are needed to understand the influence of ","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":"132 11","pages":"117001"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11540153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-27DOI: 10.1289/EHP15377
Apolline Saucy, Ana Espinosa, Susana Iraola-Guzmán, Gemma Castaño-Vinyals, Barbara N Harding, Marianna Karachaliou, Otavio Ranzani, Rafael De Cid, Judith Garcia-Aymerich, Manolis Kogevinas
{"title":"Environmental Exposures and Long COVID in a Prospective Population-Based Study in Catalonia (COVICAT Study).","authors":"Apolline Saucy, Ana Espinosa, Susana Iraola-Guzmán, Gemma Castaño-Vinyals, Barbara N Harding, Marianna Karachaliou, Otavio Ranzani, Rafael De Cid, Judith Garcia-Aymerich, Manolis Kogevinas","doi":"10.1289/EHP15377","DOIUrl":"10.1289/EHP15377","url":null,"abstract":"","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":"132 11","pages":"117701"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142726951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-27DOI: 10.1289/EHP16701
Wendee Nicole
{"title":"Erratum: \"Gut Check: Microbiota and Obesity in Mice Exposed to Polystyrene Microspheres\".","authors":"Wendee Nicole","doi":"10.1289/EHP16701","DOIUrl":"10.1289/EHP16701","url":null,"abstract":"","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":"132 11","pages":"119003"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142727050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-21DOI: 10.1289/EHP15798
Kelley Christensen
A state-of-the-science review probed whether biodiversity inside the body and in the environment were associated with certain immune responses.
一项科学研究探讨了体内和环境中的生物多样性是否与某些免疫反应有关。
{"title":"Diversity under a Microscope: As Biodiversity Diminishes, Do Allergies and Asthma Increase?","authors":"Kelley Christensen","doi":"10.1289/EHP15798","DOIUrl":"10.1289/EHP15798","url":null,"abstract":"<p><p>A state-of-the-science review probed whether biodiversity inside the body and in the environment were associated with certain immune responses.</p>","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":"132 11","pages":"114002"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11580834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-04DOI: 10.1289/EHP15844
Wendee Nicole
Gut microbes appeared to play a role in the obesity outcomes observed in mice fed manufactured polystyrene microspheres.
肠道微生物似乎在喂食人造聚苯乙烯微球的小鼠中观察到的肥胖结果中起了作用。
{"title":"Gut Check: Microbiota and Obesity in Mice Exposed to Polystyrene Microspheres.","authors":"Wendee Nicole","doi":"10.1289/EHP15844","DOIUrl":"10.1289/EHP15844","url":null,"abstract":"<p><p>Gut microbes appeared to play a role in the obesity outcomes observed in mice fed manufactured polystyrene microspheres.</p>","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":"132 11","pages":"114001"},"PeriodicalIF":10.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Exposures to chemicals, including phthalates, triphenyl phosphate, and dibutyl phosphate, have been associated with increased levels of lipid markers, such as elevated low-density lipoprotein.
{"title":"A Bigger Big Picture: Insights on Environmental Chemicals and Dyslipidemia through Combined \"Omic\" Analyses.","authors":"Charles Schmidt","doi":"10.1289/ehp15932","DOIUrl":"https://doi.org/10.1289/ehp15932","url":null,"abstract":"Exposures to chemicals, including phthalates, triphenyl phosphate, and dibutyl phosphate, have been associated with increased levels of lipid markers, such as elevated low-density lipoprotein.","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":"48 1","pages":"104002"},"PeriodicalIF":10.4,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142490660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Invited Perspective: Insights into Exposure to Industrial Solvents and Cancer Risk at Camp Lejeune.","authors":"Rena R Jones,Mark P Purdue","doi":"10.1289/ehp16102","DOIUrl":"https://doi.org/10.1289/ehp16102","url":null,"abstract":"","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":"1 1","pages":"101304"},"PeriodicalIF":10.4,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142489433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frank J Bove,April Greek,Ruth Gatiba,Betsy Kohler,Recinda Sherman,Gene T Shin,Aaron Bernstein
BACKGROUNDDrinking water at US Marine Corps Base Camp Lejeune, North Carolina, was contaminated with trichloroethylene and other industrial solvents from 1953 to 1985.METHODSA cohort cancer incidence study was conducted of Marines/Navy personnel who began service and were stationed at Camp Lejeune (N=154,821) or Camp Pendleton, California (N=163,484) between 1975 and 1985 and civilian workers employed at Camp Lejeune (N=6,494) or Camp Pendleton (N=5,797) between October 1972 and December 1985. Camp Pendleton's drinking water was not contaminated with industrial solvents. Individual-level information on primary invasive cancers and in situ bladder cancer diagnosed between 1996 and 2017 was obtained from 54 US cancer registries. Proportional hazards regression was used to calculate adjusted hazard ratios (aHRs) comparing cancer incidence between the Camp Lejeune and Camp Pendleton cohorts, adjusted for sex, race, education, and rank (or blue-collar work), with age as the time variable. Precision of aHRs was evaluated using the 95% confidence interval (CI) ratio (CIR).RESULTSCancers among Camp Lejeune Marines/Navy personnel and civilian workers totaled 12,083 and 1,563, respectively. Cancers among Camp Pendleton Marines/Navy personnel and civilian workers totaled 12,144 and 1,416, respectively. Compared with Camp Pendleton, Camp Lejeune Marines/Navy personnel had aHRs ≥1.20 with CIRs ≤3 for all myeloid cancers (HR=1.24; 95% CI: 1.03, 1.49), acute myeloid leukemia (HR=1.38; 95% CI: 1.03, 1.85), myelodysplastic and myeloproliferative syndromes (HR=1.68; 95% CI: 1.07, 2.62), polycythemia vera (HR=1.41; 95% CI: 0.94, 2.11), and cancers of the esophagus (HR=1.27; 95% CI: 1.03, 1.56), larynx (HR=1.21; 95% CI: 0.98, 1.50), soft tissue (HR=1.21; 95% CI: 0.92, 1.59), and thyroid (HR=1.22; 95% CI: 1.03, 1.45). Lymphoma subtypes mantle cell and marginal zone B-cell and lung cancer subtypes adenocarcinoma and non-small cell lung cancer also had aHRs ≥1.20 with CIRs ≤3. Compared with Camp Pendleton, Camp Lejeune civilian workers had aHRs ≥1.20 with CIRs ≤3 for all myeloid cancers (HR=1.40; 95% CI: 0.83, 2.36), squamous cell lung cancer (HR=1.63; 95% CI: 1.10, 2.41), and female breast (HR=1.21; 95% CI: 0.97, 1.52) and ductal cancer (HR=1.32; 95% CI: 1.02, 1.71).CONCLUSIONIncreased risks of several cancers were observed among Marines/Navy personnel and civilian workers exposed to contaminated drinking water at Camp Lejeune compared with Camp Pendleton. https://doi.org/10.1289/EHP14966.
{"title":"Cancer Incidence among Marines and Navy Personnel and Civilian Workers Exposed to Industrial Solvents in Drinking Water at US Marine Corps Base Camp Lejeune: A Cohort Study.","authors":"Frank J Bove,April Greek,Ruth Gatiba,Betsy Kohler,Recinda Sherman,Gene T Shin,Aaron Bernstein","doi":"10.1289/ehp14966","DOIUrl":"https://doi.org/10.1289/ehp14966","url":null,"abstract":"BACKGROUNDDrinking water at US Marine Corps Base Camp Lejeune, North Carolina, was contaminated with trichloroethylene and other industrial solvents from 1953 to 1985.METHODSA cohort cancer incidence study was conducted of Marines/Navy personnel who began service and were stationed at Camp Lejeune (N=154,821) or Camp Pendleton, California (N=163,484) between 1975 and 1985 and civilian workers employed at Camp Lejeune (N=6,494) or Camp Pendleton (N=5,797) between October 1972 and December 1985. Camp Pendleton's drinking water was not contaminated with industrial solvents. Individual-level information on primary invasive cancers and in situ bladder cancer diagnosed between 1996 and 2017 was obtained from 54 US cancer registries. Proportional hazards regression was used to calculate adjusted hazard ratios (aHRs) comparing cancer incidence between the Camp Lejeune and Camp Pendleton cohorts, adjusted for sex, race, education, and rank (or blue-collar work), with age as the time variable. Precision of aHRs was evaluated using the 95% confidence interval (CI) ratio (CIR).RESULTSCancers among Camp Lejeune Marines/Navy personnel and civilian workers totaled 12,083 and 1,563, respectively. Cancers among Camp Pendleton Marines/Navy personnel and civilian workers totaled 12,144 and 1,416, respectively. Compared with Camp Pendleton, Camp Lejeune Marines/Navy personnel had aHRs ≥1.20 with CIRs ≤3 for all myeloid cancers (HR=1.24; 95% CI: 1.03, 1.49), acute myeloid leukemia (HR=1.38; 95% CI: 1.03, 1.85), myelodysplastic and myeloproliferative syndromes (HR=1.68; 95% CI: 1.07, 2.62), polycythemia vera (HR=1.41; 95% CI: 0.94, 2.11), and cancers of the esophagus (HR=1.27; 95% CI: 1.03, 1.56), larynx (HR=1.21; 95% CI: 0.98, 1.50), soft tissue (HR=1.21; 95% CI: 0.92, 1.59), and thyroid (HR=1.22; 95% CI: 1.03, 1.45). Lymphoma subtypes mantle cell and marginal zone B-cell and lung cancer subtypes adenocarcinoma and non-small cell lung cancer also had aHRs ≥1.20 with CIRs ≤3. Compared with Camp Pendleton, Camp Lejeune civilian workers had aHRs ≥1.20 with CIRs ≤3 for all myeloid cancers (HR=1.40; 95% CI: 0.83, 2.36), squamous cell lung cancer (HR=1.63; 95% CI: 1.10, 2.41), and female breast (HR=1.21; 95% CI: 0.97, 1.52) and ductal cancer (HR=1.32; 95% CI: 1.02, 1.71).CONCLUSIONIncreased risks of several cancers were observed among Marines/Navy personnel and civilian workers exposed to contaminated drinking water at Camp Lejeune compared with Camp Pendleton. https://doi.org/10.1289/EHP14966.","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":"34 1","pages":"107008"},"PeriodicalIF":10.4,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142489432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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