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Preliminary Data Regarding Total Chlorophylls, Carotenoids and Flavonoids Content in Flavoparmelia Caperata (L.) Hale Lichens Species 毛茛中总叶绿素、类胡萝卜素和黄酮类化合物含量的初步研究地衣种类
Pub Date : 2019-10-15 DOI: 10.26417/849rvg48r
T. Negreanu-Pîrjol, R. Sîrbu, Ștefan Bogdan Negreanu-Pîrjol
Flavoparmelia caperata L. Hale (common greenshield lichen) is an Ascomycete, foliose lichen usually growing on tree bark in most mesophytic-forested habitats in Romania. Lichen samples were collected from three stations in Romania (Craiova, Timișoara, Hoia-Baciu Forest, Cluj) and extracted in 96% ethanol. Both dry lichen tissue powder and extracts were analyzed by UV-Vis spectrophotometry for determining photosynthetic pigment concentrations (chlorophylls a and b and total carotenoids). Dry tissue samples had chlorophyll a concentrations of 95.12-109.59 mg/kg DW, chlorophyll b concentrations of 88.53-110.98 mg/kg and total carotenoids 88.89-102.85 mg/kg. Alcoholic extracts of fresh lichen tissue showed an extreme variability, with 715.97-10331.50 mg/kg chlorophyll a, 527.77-8124.20 mg/kg chlorophyll b, 1125.72-8714.90 mg/kg carotenoids pigments, with the highest values in samples from Craiova. A lower variability was observed in flavonoid contents, with 461.78-966.02 mg/kg DW in dry powder and 815.56-2734.135 mg/kg in ethanolic extracts. Extracts of lichens from Craiova had a decreased content of total flavonoids compared with the other two lichens ethanol extracts.
黄衣(普通绿盾地衣)是一种子囊菌,通常生长在罗马尼亚大多数叶生森林栖息地的树皮上的毛囊地衣。地衣样品采集于罗马尼亚的三个站点(Craiova, Timișoara, Hoia-Baciu Forest, Cluj),用96%乙醇提取。用紫外-可见分光光度法测定干地衣组织粉和提取物的光合色素(叶绿素a、b和总类胡萝卜素)浓度。干组织样品叶绿素a浓度为95.12 ~ 109.59 mg/kg DW,叶绿素b浓度为88.53 ~ 110.98 mg/kg,类胡萝卜素总量为88.89 ~ 102.85 mg/kg。新鲜地衣组织酒精提取物的叶绿素a含量为715.97 ~ 10331.50 mg/kg,叶绿素b含量为527.77 ~ 8124.20 mg/kg,类胡萝卜素含量为1125.72 ~ 8714.90 mg/kg,克拉约瓦地衣样品的含量最高。黄酮类化合物含量变化幅度较小,干粉为461.78 ~ 966.02 mg/kg DW,醇提物为815.56 ~ 2734.135 mg/kg。与其他两种地衣乙醇提取物相比,克拉俄瓦地衣提取物的总黄酮含量降低。
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引用次数: 1
Residual Marine Algae Biomass - An Important Raw Material for Obtaining a Soil Biostimulator-Regenerator 海洋藻类的残余生物量——获得土壤生物刺激-再生器的重要原料
Pub Date : 2019-10-15 DOI: 10.26417/749ztk83f
B. Negreanu-Pirjol, T. Negreanu-Pîrjol, G. Paraschiv
This paper highlight a study regarding the valorification of residual marine algae biomass along Romanian Black Sea Coast, which recorded in the last summer period an accumulation of a large seaweed biomass quantities. The valorization of this waste was conceived as a result of theirs nutritional potential for improvind degraded soils of Dobrudja region, Romania and as complex capitalization of this biomass. It was establish the biotechnological process for the new biosolid nutrient composite obtaining. The parameter physical-chemical results of raw material used for biofertilizer obtaining, emphasized an increased organic charge compared with the inorganic compounds. Also, an increased value of total organic nitrogen and an optimum pH limits, was registered. Regarding the nutrients concentrations values, it could be noticed that the new biosolid fertilizer contains organic matter and valuable nutritive elements (N, P) could be contributed to the enhancement of the soil quality. The new biosolid biostimulator-regenerator obtained from natural residues bring a complex of nutrients for degraded soils by the presence of organic residual compounds, through the proteins, lipids, nutrients (nitrogen, phosphorus) and mineral salts content, necessary for plants nutrition and improvement of soils quality.
本文重点介绍了一项关于罗马尼亚黑海沿岸残留海藻生物量的增值研究,该研究记录了去年夏季大量海藻生物量的积累。这种废物的增值被认为是由于它们具有改善罗马尼亚多布鲁贾地区退化土壤的营养潜力,并作为这种生物质的复杂资本化。建立了新型生物固体营养复合物制备的生物工艺流程。生物肥料原料的参数理化结果表明,与无机化合物相比,有机电荷增加。此外,总有机氮的增加值和最佳pH值限值也得到了记录。在养分浓度值方面,新型生物固体肥料含有有机质和有价值的营养元素(N, P),可以促进土壤质量的提高。从天然残留物中获得的新型生物固体生物刺激-再生器通过有机残留物化合物的存在,通过蛋白质,脂质,营养物质(氮,磷)和无机盐含量,为退化土壤带来复合营养物质,这是植物营养和改善土壤质量所必需的。
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引用次数: 2
Studies on Improving Solubility in Different Media for Said Formulations with Topical Application 局部应用提高该制剂在不同介质中的溶解度的研究
Pub Date : 2019-10-15 DOI: 10.26417/963uti35x
Emin Cadâr, A. Ionescu, R. Sîrbu
The studied compounds are gels with meloxicam, piroxicam and tenoxicam in different solvents. The problem of solubilization of these compounds is generated by their poor solubility in hydrophilic media. Also, when applying local non-steroidal anti-inflammatory drugs (NSAIDs) in the form of ointments, the local concentration of the active substance is much higher than in the untreated tissue. The amount of NSAIDs required to produce a therapeutic effect by topical administration is much lower than in oral administration. Side effects may, however, occur as a local irritation from the time a topical formulation is applied. This paper presents the solubilization tests performed for pharmaceutical compounds of the NSAID class in different hydrophilic media. The test conclusions are useful because their solubility can be increased by using solvents (polar or non-polar) and surfactants. The conclusions of the solubility tests help in choosing solvents in the formulation and technologicalization of semi-solid preparations with topical application.
所研究的化合物是在不同溶剂中与美洛昔康、吡罗西康和替诺昔康的凝胶。这些化合物的增溶问题是由于它们在亲水性介质中的溶解度差而产生的。此外,当以软膏的形式局部应用非甾体抗炎药(NSAIDs)时,活性物质的局部浓度远高于未经治疗的组织。局部给药产生治疗效果所需的非甾体抗炎药的剂量远低于口服给药。然而,副作用可能会在局部配方应用后出现局部刺激。本文介绍了非甾体抗炎药类药物化合物在不同亲水性介质中的增溶试验。测试结论是有用的,因为它们的溶解度可以通过使用溶剂(极性或非极性)和表面活性剂来提高。溶解度试验的结论有助于外用半固体制剂的配方和工艺的选择。
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引用次数: 0
Comparison of Extraction Methods of Chitin and Chitosan from Different Sources 不同来源甲壳素和壳聚糖提取方法的比较
Pub Date : 2019-10-15 DOI: 10.26417/688wvv48e
Alef Ibram, A. Ionescu, Emin Cadâr
Chitin and chitosan have become of great interest not only as underutilized resources, but also as new functional materials of high potential in various fields. The methods of isolating chitosan from different sources: shrimp (Panaeus monodon), crab (Scylla olivicea and Scylla serrata), locust (Schistocerca gregaria), honeybee (Apis mellifera), beelte (Calosoma rugosa) and fish (Labeo rohita) were compared. The same steps of demineralization and deproteinization were followed for the chemical extraction of chitin, but the concentration of reagents, the temperatures and reaction times were varied, which resulted in chitosans with different degrees of deacetylation.
几丁质和壳聚糖不仅是一种未被充分利用的资源,而且是一种具有广泛应用前景的新型功能材料。比较了不同来源虾(Panaeus monodon)、蟹(Scylla olivicea和Scylla serrata)、蝗虫(Schistocerca gregaria)、蜜蜂(Apis mellifera)、甲虫(Calosoma rugosa)和鱼(Labeo rohita)中壳聚糖的分离方法。化学提取几丁质的脱矿和脱蛋白步骤相同,但试剂浓度、温度和反应时间不同,导致壳聚糖脱乙酰程度不同。
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引用次数: 4
Carotid Atherosclerosis and Lacunar Stroke a Possible Association 颈动脉粥样硬化与腔隙性中风可能存在关联
Pub Date : 2019-05-15 DOI: 10.2478/ejmn-2018-0009
A. Ionescu, N. Carciumaru, S. Chirila, R. Sîrbu
Abstract Stroke remain the third cause of death and a major cause of disability worldwide. Our modern time enemy, atherosclerosis, with his many faces, is strongly related with stroke and its major subtypes. Ischemic stroke account up to 80 % of all stroke. As a subtype of ischemic stroke, lacunar infarcts remain an important concern. Aim of this study is to correlate carotid disease findings with lacunar stroke. We studied a group of 129 patients with carotid disease, and we established a possible relationship with lacunar stroke. Ultrasonography findings were correlated with the presence of lacunar stroke, confirmed by CT scan. Our study demonstrate that carotid plaques number could be a good predictor for lacunar stroke risk. External carotid plaques number is strongly correlate with lacunar stroke presence.
中风仍然是世界上第三大死因和致残的主要原因。我们现代的敌人,动脉粥样硬化,有着多种面貌,与中风及其主要亚型密切相关。缺血性中风占所有中风的80%。作为缺血性脑卒中的一种亚型,腔隙性梗死仍然是一个重要的问题。本研究旨在探讨颈动脉疾病与腔隙性脑卒中的相关性。我们研究了一组129例颈动脉疾病患者,我们建立了颈动脉疾病与腔隙性卒中的可能关系。超声检查结果与腔隙性脑卒中的存在相关,经CT扫描证实。我们的研究表明,颈动脉斑块数量可以很好地预测腔隙性卒中的风险。颈外动脉斑块数量与腔隙性卒中存在密切相关。
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引用次数: 0
Identity Narrative as an Unconscious Scaffold for Human Autobiography 身份叙事作为人类自传的无意识支架
Pub Date : 2019-05-15 DOI: 10.26417/929uar53c
A. Novac, M. Tuttle, R. Bota, B. Blinder
Abstract Over the past years, a multi-disciplinary literature on the significance of personal narratives in autobiography and identity has emerged. This subject has been of interest to authors in the fields of humanities, psychology, and medicine alike. In this paper, we are proposing the term Identity Narrative (IdN) to define a cognitive and emotional framework that serves as an implicit (unconscious) scaffolding of memory on which to build human autobiography. The authors first classify narratives into external (universal history, the humanities, culture) and internal (autobiography, based on personal experiences, both directly and indirectly, through identification and education). All philosophy and social commentary has utilized history for the purposes of prediction and meaning-making. Personalities including Aristotle, St. Augustine, Rousseau, Freud, Marx, Spengler, and Benjamin Franklin have reread history to gain insight about human nature. History has inspired the enlightenment and renaissance of a new reality for humanity. It is widely known that history can also be misused to justify aggression and human suffering. The use of history to create deep convictions that annihilate moral imperatives is only possible because of unconsciously consolidated internal narratives, the IdN. IdN is reshaped through life, both by “bottom-up” acquisition of information, as well as a “top-down” learning model, which includes the following circumstances: (a) sudden insight and awareness; (b) experiences with high emotional valence; (c) high frequency of repetition; and (d) prolonged duration of exposure. In this way, IdN, a form of relatively stable unconscious, anoetic memory, provides a “first-person” experience to autobiography. Autobiography then, becomes part of auto-noetic consciousness, the human ability to mentally time travel and have self-knowledge. IdN parallels lifelong growth and development, language acquisition, and maturing of attachment. The extensive brain activation during communication and speech, revealed by neuroimaging studies, will be referred to as the “communication beltway.” We hypothesize that the alternation in activation between the default mode (midline structures) of the brain (previously associated with the Self) and the language brain creates a platform that encodes crucial components of IdN throughout life. In this way, IdN, autobiographical memory, and the language brain are parts of a larger biological substrate of social affiliations.
摘要近年来,关于个人叙事在自传和身份中的意义的多学科文献出现了。这个主题引起了人文、心理学和医学领域作者的兴趣。在本文中,我们提出了“身份叙事”(Identity Narrative, IdN)一词来定义一个认知和情感框架,作为一个内隐的(无意识的)记忆支架,在此基础上构建人类自传。作者首先将叙事分为外部(世界历史、人文、文化)和内部(自传,以个人经历为基础,通过认同和教育直接或间接地进行)。所有的哲学和社会评论都利用历史来预测和创造意义。包括亚里士多德、圣奥古斯丁、卢梭、弗洛伊德、马克思、斯宾格勒和本杰明·富兰克林在内的名人都曾重读历史,以深入了解人性。历史激发了人类新现实的启蒙和复兴。众所周知,历史也可以被滥用来为侵略和人类苦难辩护。利用历史来创造深刻的信念,从而消灭道德准则,只有在无意识地巩固内部叙事的情况下才有可能。IdN是通过生活重塑的,既通过“自下而上”的信息获取,也通过“自上而下”的学习模式,其中包括以下情况:(a)突然顿悟和意识;(b)高情绪效价的经历;(c)重复频率高;(d)暴露时间延长。这样,IdN作为一种相对稳定的无意识、厌食性记忆形式,为自传提供了一种“第一人称”体验。然后自传,成为自我意识的一部分,人类精神上的时间旅行和自我认识的能力。IdN与终身成长和发展、语言习得和依恋成熟相对应。神经成像研究显示,在交流和说话过程中,大脑的广泛激活将被称为“交流环城公路”。我们假设,大脑的默认模式(中线结构)(之前与自我相关)和语言大脑之间的激活交替创造了一个平台,在整个生命过程中编码IdN的关键组成部分。这样看来,IdN、自传式记忆和语言大脑都是社会关系这一更大的生物基础的组成部分。
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引用次数: 1
New Formulation with Marine Algae from Black Sea 黑海海藻新配方
Pub Date : 2018-12-01 DOI: 10.2478/ejmn-2018-0013
Emin Cadâr, Emilia Mihaela Cadar, C. Erimia, A. Tomescu
Abstract Seaweed is a natural treasure that can be intensely evaluated for therapeutic purposes. During the past years, it became obvious that the ecosystem presents a marine algae excedent, which should be utilized in one way or another. Marine algae have been intensely studied. The superior exploitation of the marine biomass represents a highly important resource for the pharmaceutical industry, supplying raw material for the extraction of bioactive substances (vitamins, sterols, and aminoacids) and various other substances, the purity of which is strongly connected to the state of the marine ecosystem. In present work the extracts from marine algae are incorporated in type I non-denatured fibrillar collagen matrixes for obtain new pharmaceutical product. In order to obtain therapeutic effects at nanostructure level, it is important to know the rheological characteristics of the relevant mixtures of collagen gels and extracts from marine algae selected for use. In this survey we have studied mixtures made of non-denatured fibrillar collagen hydro-gels where different concentrations of marine algae have been incorporated.
海藻是一种天然宝藏,可以强烈评估治疗目的。在过去的几年里,很明显,生态系统呈现出一个海洋藻类的优势,应该以这样或那样的方式利用它。人们对海藻进行了深入的研究。对海洋生物质的高度开发是制药业的一种非常重要的资源,为提取生物活性物质(维生素、甾醇和氨基酸)和各种其他物质提供原料,这些物质的纯度与海洋生态系统的状态密切相关。本研究将海藻提取物掺入I型非变性纤维性胶原蛋白基质中制备新药。为了在纳米结构水平上获得治疗效果,了解所选择的胶原凝胶和海藻提取物的相关混合物的流变学特性是很重要的。在这项调查中,我们研究了由非变性纤维胶原蛋白水凝胶制成的混合物,其中加入了不同浓度的海藻。
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引用次数: 0
Subsidiarity in Environmental Issues: Nuances and Shifts 环境问题的辅助性:细微差别和变化
Pub Date : 2018-07-17 DOI: 10.26417/EJNM.V1I2.P17-24
Florencio R. Riguera
Abstract Although subsidiarity is dipolar, preference has been for the “lower” pole at the early stages of its development as a principle in Quadragesimo Anno: the “higher” administrative unit should act only if the “lower” unit could not deal with the issue. But in a generation, Pacem in Terris posited a nuance that put the preference on the “higher” unit. The capabilities of “higher” units could supersede the rights of “lower” units because the “on reserve” aid from “higher” units leads to more effectivity. Then, applying integral ecology, Laudato Si’ put the preference on the “higher” pole when issues are environmental in character. This stems from an understanding of complex and interconnected mechanisms in the interaction between populations and the environment. Because Nature has predetermined ways of acting and reacting to events like those caused by populations, Nature relays the impact of actions, such as environmental backlash, to other locations, sections, or later generations; it can also “slap back” at the local agents of events. Thus, the default option should be for the “higher” units to act when it comes to researching the complex interconnections of actions at the ecological level. But this option can lead to gaming the deliberations on public policy with questions of uncertainty or risk because valid understanding is needed to guide actions or policies. Perspectives broader than the local in terms of understanding and of values to be shared are needed.
虽然辅助性是双极性的,但在其发展的早期阶段,作为《四元论》的一项原则,优先考虑的是“较低”极:只有当“较低”单位无法处理问题时,“较高”行政单位才应该采取行动。但在一代人的时间里,《Pacem in Terris》设定了一个细微差别,将偏好放在“更高”的单位上。“较高”单位的能力可以取代“较低”单位的权利,因为“较高”单位的“备用”援助导致更有效。然后,运用整体生态学,Laudato Si在环境问题上倾向于“更高”的极点。这源于对人口与环境之间相互作用的复杂和相互联系机制的理解。因为大自然有预先确定的行动和反应方式,比如由人口引起的事件,大自然会把环境反弹等行动的影响传递给其他地点、部分或后代;它还可以“回击”事件的本地代理。因此,当涉及到研究生态层面的复杂相互关系时,默认的选择应该是由“更高”的单位来行动。但是,这种选择可能会导致对公共政策的审议存在不确定性或风险问题,因为需要有效的理解来指导行动或政策。在理解和共享价值方面,需要比当地更广泛的视角。
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引用次数: 0
Impact of location and government funding on medical Students Perception of Learning Environment in Nigeria 地点和政府资助对尼日利亚医学生对学习环境感知的影响
Pub Date : 2018-07-17 DOI: 10.26417/ejnm.v1i2.p5-16
Kenneth Oghagbon Efosa
0
0
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引用次数: 1
The Examination of the Profile of Leadership and Management in Healthcare Institutions in Kosovo 对科索沃保健机构领导和管理概况的审查
Pub Date : 2018-07-17 DOI: 10.26417/EJNM.V1I2.P36-51
A. Bytyqi, Bujar Gallopeni
0
0
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引用次数: 0
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European Journal of Medicine and Natural Sciences
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