Pieter J. Kievit, M. Schoorl, Jeannette Oomes, Piet Bartels
Abstract In the third era of quality assurance in health care, innovation is no longer the exclusive focus area of the individual medical professional dedicated to optimizing patient care nor is it achieved by design thinking by the health delivery organization aiming for economic sustainability. Change platform in the third era is the community of professionals, committed to providing the best possible care within the limits of organizational logic. We aim to clarify the conditions for sustainable quality improvement in health delivery organizations and in doing so to provide a means of improving initial feasibility assessment by identifying critical factors in the cooperation between different parties. We designed a model representing the sources of influence on the process of decision making regarding the selection of innovations and choosing the most effective implementation strategy. These sources are: aspects of legitimacy, core values and change readiness. We tested this model on a project, aimed at improving the efficiency of the OR in a Dutch University Clinic. The example project failed to deliver the projected outcome because of non-disclosed conflicting interpretations of core values and an implicit controversial status shift between medical professionals and OR management. This confirms the explaining power of our model. Successful implementation of quality innovation in health care depends (among other things) on addressing the challenges of differing concepts of legitimacy, conflicting core values and varying change readiness between social systems in complex organizations. Installing a QIC as such does not meet these challenges.
{"title":"Quality Innovation in Healthcare – The Challenge of the Third Era","authors":"Pieter J. Kievit, M. Schoorl, Jeannette Oomes, Piet Bartels","doi":"10.26417/303oix63f","DOIUrl":"https://doi.org/10.26417/303oix63f","url":null,"abstract":"Abstract In the third era of quality assurance in health care, innovation is no longer the exclusive focus area of the individual medical professional dedicated to optimizing patient care nor is it achieved by design thinking by the health delivery organization aiming for economic sustainability. Change platform in the third era is the community of professionals, committed to providing the best possible care within the limits of organizational logic. We aim to clarify the conditions for sustainable quality improvement in health delivery organizations and in doing so to provide a means of improving initial feasibility assessment by identifying critical factors in the cooperation between different parties. We designed a model representing the sources of influence on the process of decision making regarding the selection of innovations and choosing the most effective implementation strategy. These sources are: aspects of legitimacy, core values and change readiness. We tested this model on a project, aimed at improving the efficiency of the OR in a Dutch University Clinic. The example project failed to deliver the projected outcome because of non-disclosed conflicting interpretations of core values and an implicit controversial status shift between medical professionals and OR management. This confirms the explaining power of our model. Successful implementation of quality innovation in health care depends (among other things) on addressing the challenges of differing concepts of legitimacy, conflicting core values and varying change readiness between social systems in complex organizations. Installing a QIC as such does not meet these challenges.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"1 1","pages":"79 - 99"},"PeriodicalIF":0.0,"publicationDate":"2020-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81235338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This paper accentuates Data Analytics as a broad term that encapsulates the issues in processing of a large structured and unstructured data in clinical healthcare. The paper explores the potential of Data Analytics in Changing Health Behavior (CHB), especially amongst the youth with regard to biomedical and well-being informatics, which plots the essential attributes of Big Data and delineates the relations among restorative and well-being informatics. The translational bio-informatics, sensor informatics and clinical diagnosis help a person in effective management of their wellness and prosperity. Data Analytics has the potential to harness diagnostic information not only to obviate morbidity to a great extent, but also bring down the expenses on therapeutic and/or clinical diagnosis, intervention and management.
{"title":"Changing Health-Related Behaviour Leveraging Data Analytics","authors":"R. Ranjan, S. Bhargav","doi":"10.26417/179kke60g","DOIUrl":"https://doi.org/10.26417/179kke60g","url":null,"abstract":"This paper accentuates Data Analytics as a broad term that encapsulates the issues in processing of a large structured and unstructured data in clinical healthcare. The paper explores the potential of Data Analytics in Changing Health Behavior (CHB), especially amongst the youth with regard to biomedical and well-being informatics, which plots the essential attributes of Big Data and delineates the relations among restorative and well-being informatics. The translational bio-informatics, sensor informatics and clinical diagnosis help a person in effective management of their wellness and prosperity. Data Analytics has the potential to harness diagnostic information not only to obviate morbidity to a great extent, but also bring down the expenses on therapeutic and/or clinical diagnosis, intervention and management.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73945840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract The sociological, psychological and physiological problems experienced by humanity, which have been exposed to dark offices, high flats and city life far from nature, have been strikingly exposed with researches. In addition, the nature-based design approaches that emerged due to the need to meet the need of humanity for nature and the desire to return to nature have taken their place among the design parameters of the new age in architecture However, concepts where biology and design come together have emerged. Biomimicry is a discipline that explores the best ideas for design processes by imitating nature. It takes all the ecological needs that users expect from architecture directly from the nature. It provides an integration model with the nature that people yearn for, and also creates a model that takes the solutions created by nature in architectural designs as an example. In this period of architectural design turning to nature, biomimicry has the feature of being a pioneer of a new architectural trend by providing designers with a different view of nature. The main purpose of this study is to determine the application areas and basic features of the biomimicry approach in architecture and to create a road map for designer architects. To achieve this goal, a research methodology has been designed to achieve two objectives. First, it will carry out an in-depth research on biomimicry, architecture and environmentally friendly designs with existing literature studies. Secondly, listing the biomimicry designs applied in architecture and classifying them according to their ecological gains to the building. As a result, a guide will be created for the designer architects to provide ease in producing more efficient buildings.
{"title":"Effects of Biomimicry on Architecture","authors":"Elif Gizem Yetkin","doi":"10.26417/219dlh28l","DOIUrl":"https://doi.org/10.26417/219dlh28l","url":null,"abstract":"Abstract The sociological, psychological and physiological problems experienced by humanity, which have been exposed to dark offices, high flats and city life far from nature, have been strikingly exposed with researches. In addition, the nature-based design approaches that emerged due to the need to meet the need of humanity for nature and the desire to return to nature have taken their place among the design parameters of the new age in architecture However, concepts where biology and design come together have emerged. Biomimicry is a discipline that explores the best ideas for design processes by imitating nature. It takes all the ecological needs that users expect from architecture directly from the nature. It provides an integration model with the nature that people yearn for, and also creates a model that takes the solutions created by nature in architectural designs as an example. In this period of architectural design turning to nature, biomimicry has the feature of being a pioneer of a new architectural trend by providing designers with a different view of nature. The main purpose of this study is to determine the application areas and basic features of the biomimicry approach in architecture and to create a road map for designer architects. To achieve this goal, a research methodology has been designed to achieve two objectives. First, it will carry out an in-depth research on biomimicry, architecture and environmentally friendly designs with existing literature studies. Secondly, listing the biomimicry designs applied in architecture and classifying them according to their ecological gains to the building. As a result, a guide will be created for the designer architects to provide ease in producing more efficient buildings.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"96 1","pages":"100 - 113"},"PeriodicalIF":0.0,"publicationDate":"2020-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84969969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Renal hyperparathyroidism (rHPT) is a common complication of chronic kidney disease characterized by elevated parathyroid hormone levels secondary to derangements in the homeostasis of calcium, phosphate, and vitamin D. Patients with rHPT experience increased rates of cardiovascular problems and bone disease. The Kidney Disease: Improving Global Outcomes guidelines recommend that screening and management of rHPT be initiated for all patients with chronic kidney disease stage 3 (estimated glomerular filtration rate, - 60 mL/min/1.73 m2). Since the 1990s, improving medical management with vitamin D analogs, phosphate binders, and calcimimetic drugs has expanded the treatment options for patients with rHPT, but some patients still require a parathyroidectomy to mitigate the sequelae of this challenging disease.
{"title":"Calcium, Phosphorus and PTH in Patients with End Stage of Chronic Kidney Disease, Undergoing Hemodialysis","authors":"S. Faja, A. Shoshi","doi":"10.26417/214rmd38q","DOIUrl":"https://doi.org/10.26417/214rmd38q","url":null,"abstract":"Renal hyperparathyroidism (rHPT) is a common complication of chronic kidney disease characterized by elevated parathyroid hormone levels secondary to derangements in the homeostasis of calcium, phosphate, and vitamin D. Patients with rHPT experience increased rates of cardiovascular problems and bone disease. The Kidney Disease: Improving Global Outcomes guidelines recommend that screening and management of rHPT be initiated for all patients with chronic kidney disease stage 3 (estimated glomerular filtration rate, - 60 mL/min/1.73 m2). Since the 1990s, improving medical management with vitamin D analogs, phosphate binders, and calcimimetic drugs has expanded the treatment options for patients with rHPT, but some patients still require a parathyroidectomy to mitigate the sequelae of this challenging disease.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89499767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Anxiety disorder is the most frequent psychiatric problem among children and adolescents. Research proved that resilience can be a protective factor in coping with psychological difficulties. Our research focuses on these aspects of resilience. Aims: We aimed to investigate the resilience and anxiety level of families with adolescents who were diagnosed with anxiety disorders. Method: The clinical sample included 40 adolescents who were diagnosed with anxiety disorders and who received ambulant treatment. (18 boys and 22 girls; age: M=13.37 years, SD=1.46). Members of the control group were recruited from schools and they were normally developing adolescents without any psychiatric diagnosis. (18 boys and 19 girls, age: M=13.7 years; SD=1.56) DASS-21, Ten items Connor-Davidson Resilience Scale and self-made demographic sheet were used. Results: Regarding the resilience, a Significant difference was found between the clinical and the sample group both among the mothers and their children. However, in the case of fathers, no discrepancy was found. Our results suggest that there is a significant, moderate positive relationship between the resilience of the mother and their children. Nevertheless, similar mechanisms in the fathers’ case cannot be registered. In the control group, the fathers’ perception of their child’s resilience proved to be the strongest predictive factor (beta=0,495). On the contrary in the clinical group, the maternal perception was more accurate. (beta=0,06). Conclusions: Resilience can serve as a protective factor against anxiety. Our results can be useful for practitioners and draw attention to the importance of intrafamily mechanisms in coping with anxiety and mood disorders.
{"title":"Resilience of adolescents diagnosed with anxiety and their parents in clinical sample","authors":"Törő Kd, S. Takács, G. Csikós","doi":"10.31234/osf.io/f2ux8","DOIUrl":"https://doi.org/10.31234/osf.io/f2ux8","url":null,"abstract":"Introduction: Anxiety disorder is the most frequent psychiatric problem among children and adolescents. Research proved that resilience can be a protective factor in coping with psychological difficulties. Our research focuses on these aspects of resilience. Aims: We aimed to investigate the resilience and anxiety level of families with adolescents who were diagnosed with anxiety disorders. Method: The clinical sample included 40 adolescents who were diagnosed with anxiety disorders and who received ambulant treatment. (18 boys and 22 girls; age: M=13.37 years, SD=1.46). Members of the control group were recruited from schools and they were normally developing adolescents without any psychiatric diagnosis. (18 boys and 19 girls, age: M=13.7 years; SD=1.56) DASS-21, Ten items Connor-Davidson Resilience Scale and self-made demographic sheet were used. Results: Regarding the resilience, a Significant difference was found between the clinical and the sample group both among the mothers and their children. However, in the case of fathers, no discrepancy was found. Our results suggest that there is a significant, moderate positive relationship between the resilience of the mother and their children. Nevertheless, similar mechanisms in the fathers’ case cannot be registered. In the control group, the fathers’ perception of their child’s resilience proved to be the strongest predictive factor (beta=0,495). On the contrary in the clinical group, the maternal perception was more accurate. (beta=0,06). Conclusions: Resilience can serve as a protective factor against anxiety. Our results can be useful for practitioners and draw attention to the importance of intrafamily mechanisms in coping with anxiety and mood disorders.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"59 35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90844659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
During the past years, it became obvious that the ecosystem presents a marine algae excedent, which should be utilized in one way or another. In the marine world, algae have been intensely studied, but the Black Sea seaweeds are not sufficiently harnessed. To survive in such various diverse and extreme environments, macroalgae produce a variety of natural bioactive compounds and metabolites, such as polysaccharides, polyunsaturated fatty acids, and phlorotannins. In the Black Sea there are three species of green algae: Ulvae lactuca sp., Enteromorpha intestinalis and Cladophora sp. The superior exploitation of the marine biomass represents a highly important resource for the pharmaceutical industry, supplying raw material for the extraction of bioactive substances (vitamins, polysaccharides, sterols, phenols and amino-acids) and various other substances. The purity of this compounds is strongly connected to the state of the marine ecosystem. In the present paper are presented the main bioactive compounds existing in the chemical composition of the green algae in the Black Sea studied. The details of the therapeutic properties of the green algae generated by their chemical compositions.
{"title":"Bioactive Compounds from Three Green Algae Species along Romanian Black Sea Coast with Therapeutically Properties","authors":"R. Sîrbu, T. Negreanu-Pîrjol, M. Mirea","doi":"10.26417/720mnv73y","DOIUrl":"https://doi.org/10.26417/720mnv73y","url":null,"abstract":"During the past years, it became obvious that the ecosystem presents a marine algae excedent, which should be utilized in one way or another. In the marine world, algae have been intensely studied, but the Black Sea seaweeds are not sufficiently harnessed. To survive in such various diverse and extreme environments, macroalgae produce a variety of natural bioactive compounds and metabolites, such as polysaccharides, polyunsaturated fatty acids, and phlorotannins. In the Black Sea there are three species of green algae: Ulvae lactuca sp., Enteromorpha intestinalis and Cladophora sp. The superior exploitation of the marine biomass represents a highly important resource for the pharmaceutical industry, supplying raw material for the extraction of bioactive substances (vitamins, polysaccharides, sterols, phenols and amino-acids) and various other substances. The purity of this compounds is strongly connected to the state of the marine ecosystem. In the present paper are presented the main bioactive compounds existing in the chemical composition of the green algae in the Black Sea studied. The details of the therapeutic properties of the green algae generated by their chemical compositions.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81279968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The complex valorification of seaweed biomass represents a highly important resource for the pharmaceutical and dermo-cosmetic industry, supplying raw material for the extraction of bioactive substances such as, polysaccharides, vitamins, sterols, aminoacids, polyphenols and minerals. Marine algae represent an indefatigability resource of therapeutic active principles for diseases treatment of magnesium deficiency. The presence of chlorophyll pigments in the green algae confirms the magnesium existence, as central element in molecular structures. The main green algae, as Ulva lactuca and Enteromorpha intestinalis present on the Romanian Black Sea Coast, belong to Chlorophyta sp. In this paper we present a study of antioxidant activity correlated with magnesium content and chlorophyll pigments of the green algae Enteromorpha intestinalis and Ulva rigida (syn. Ulva lactuca) hydroalcoholic extracts. For chlorophyll pigments determination, the UV-Vis spectrometry was used. Magnesium content had been determined by absorption atomic spectrometry method, using HR-CS- AAS ContraA 700 apparatus, Analytik Jena and for total antioxidant capacity of green algae extracts, the photochemiluminescence method had been applied, using Photochem Analytik Jena apparatus. The comparative studies on two marine green algae extracts confirm the high magnesium content correlated with a high level of total antioxidant capacity for both species. The results obtained emphasize the possibility to enlarge the options to use these natural vegetal resources from Black Sea Coast, in different degenerative diseases therapy.
海藻生物质的复杂增值是制药和皮肤化妆品行业非常重要的资源，为提取生物活性物质(如多糖、维生素、甾醇、氨基酸、多酚和矿物质)提供原料。海藻是治疗缺镁疾病的一种不倦的治疗活性原理资源。绿藻中叶绿素色素的存在证实了镁作为分子结构中心元素的存在。罗马尼亚黑海沿岸的主要绿藻是绿藻类门(chlorophyll sp.)。本文研究了绿藻类Enteromorpha lactinalis和Ulva rigida(同称Ulva lactuca)水醇提取物的抗氧化活性与镁含量和叶绿素色素的关系。叶绿素色素的测定采用紫外可见光谱法。采用HR-CS- AAS contra 700仪器和Analytik Jena仪器，采用吸收原子光谱法测定绿藻提取物的镁含量;采用光化学发光法测定绿藻提取物的总抗氧化能力。通过对两种海藻提取物的对比研究，证实了两种海藻提取物中镁含量高与总抗氧化能力高相关。获得的结果强调了在不同的退行性疾病治疗中扩大使用黑海沿岸这些天然植物资源的可能性。
{"title":"Antioxidant Activity Correlated with Chlorophyll Pigments and Magnesium Content of Some Green Seaweeds","authors":"T. Negreanu-Pîrjol, R. Sîrbu, M. Mirea","doi":"10.26417/393qel95l","DOIUrl":"https://doi.org/10.26417/393qel95l","url":null,"abstract":"The complex valorification of seaweed biomass represents a highly important resource for the pharmaceutical and dermo-cosmetic industry, supplying raw material for the extraction of bioactive substances such as, polysaccharides, vitamins, sterols, aminoacids, polyphenols and minerals. Marine algae represent an indefatigability resource of therapeutic active principles for diseases treatment of magnesium deficiency. The presence of chlorophyll pigments in the green algae confirms the magnesium existence, as central element in molecular structures. The main green algae, as Ulva lactuca and Enteromorpha intestinalis present on the Romanian Black Sea Coast, belong to Chlorophyta sp. In this paper we present a study of antioxidant activity correlated with magnesium content and chlorophyll pigments of the green algae Enteromorpha intestinalis and Ulva rigida (syn. Ulva lactuca) hydroalcoholic extracts. For chlorophyll pigments determination, the UV-Vis spectrometry was used. Magnesium content had been determined by absorption atomic spectrometry method, using HR-CS- AAS ContraA 700 apparatus, Analytik Jena and for total antioxidant capacity of green algae extracts, the photochemiluminescence method had been applied, using Photochem Analytik Jena apparatus. The comparative studies on two marine green algae extracts confirm the high magnesium content correlated with a high level of total antioxidant capacity for both species. The results obtained emphasize the possibility to enlarge the options to use these natural vegetal resources from Black Sea Coast, in different degenerative diseases therapy.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81962792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Considering the concern of the European Union to implement an internal market for cosmetic products which also ensures a high level of human health protection and that cosmetics is one of the industrial activities in the EU affected by counterfeiting, which may increase the risks to human health, this article examines how European horizontal legislation is implemented in national law. This article aims to present the legal instruments created at EU level to consolidate the safety of cosmetic products and to strengthen the surveillance of the cosmetic products introduced on the market, but also to protect consumers, taking into account that in order to ensure an effective control of the market it is necessary to have a high degree of administrative cooperation between the competent authorities of the Member States. Moreover, the article aims to present the active role undertaken by the cosmetics industry in developing alternative testing methods within the Horizon 2020 Programme.
{"title":"Harmonization of the National Legislation on Cosmetic Products in the Context of the Standardization of the European Legislation in the Field","authors":"C. Erimia","doi":"10.26417/935wqz80s","DOIUrl":"https://doi.org/10.26417/935wqz80s","url":null,"abstract":"Considering the concern of the European Union to implement an internal market for cosmetic products which also ensures a high level of human health protection and that cosmetics is one of the industrial activities in the EU affected by counterfeiting, which may increase the risks to human health, this article examines how European horizontal legislation is implemented in national law. This article aims to present the legal instruments created at EU level to consolidate the safety of cosmetic products and to strengthen the surveillance of the cosmetic products introduced on the market, but also to protect consumers, taking into account that in order to ensure an effective control of the market it is necessary to have a high degree of administrative cooperation between the competent authorities of the Member States. Moreover, the article aims to present the active role undertaken by the cosmetics industry in developing alternative testing methods within the Horizon 2020 Programme.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73281813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract The antibiotic resistance and especially mult-idrug resistance is one of the most important factors for any microorganism survival in nature. In a majority of cases the resistance to antibiotics, as a property is being defined by several genes which are localized in plasmids, transposons and in other mobile genetical elements. As a result, it has been found out that in some native opportunistic pathogenic soil strains of Pseudomonas and Stenotrophomonas, the resistance to different antibiotics is caused by simultaneous presence of different plasmids in cells. Besides, the genes of resistance to various classes of antibiotics of I, II, III generations. They can be localized on one plasmid or in more than one plasmids of current bacterial cell. These plasmids of researched strains of Pseudomonas and Stenotrophomonas are able to stabile replication not only in cells permanently contacting with compatible antibiotic molecules in environment, but also in case of long-term cultivation of bacteria on synthetic media without any antibiotic. The antibiotic resistance of researched Pseudomonas and Stenotrophomonas strains, which is caused by mobile genetical elements, can be transferred among the microorganisms both in frames of one species and in interspecific and intergeneric gene transfer processes. The plasmids with the presence of genes of resistance to different antibiotics can be transferred to different microorganisms independently, with the forming of new resistant strains, which are differing in resistance to natural antimicrobial organic acidcs as well as their synthetic derivatives and it has a significant ecological and medical importance.
{"title":"The Plasmid Differences in Multi-Drug Resistant Opportunistic Pathogenic Soil Strains of Pseudomonas and Stenotrophomonas","authors":"B. Babayan","doi":"10.26417/181efp62c","DOIUrl":"https://doi.org/10.26417/181efp62c","url":null,"abstract":"Abstract The antibiotic resistance and especially mult-idrug resistance is one of the most important factors for any microorganism survival in nature. In a majority of cases the resistance to antibiotics, as a property is being defined by several genes which are localized in plasmids, transposons and in other mobile genetical elements. As a result, it has been found out that in some native opportunistic pathogenic soil strains of Pseudomonas and Stenotrophomonas, the resistance to different antibiotics is caused by simultaneous presence of different plasmids in cells. Besides, the genes of resistance to various classes of antibiotics of I, II, III generations. They can be localized on one plasmid or in more than one plasmids of current bacterial cell. These plasmids of researched strains of Pseudomonas and Stenotrophomonas are able to stabile replication not only in cells permanently contacting with compatible antibiotic molecules in environment, but also in case of long-term cultivation of bacteria on synthetic media without any antibiotic. The antibiotic resistance of researched Pseudomonas and Stenotrophomonas strains, which is caused by mobile genetical elements, can be transferred among the microorganisms both in frames of one species and in interspecific and intergeneric gene transfer processes. The plasmids with the presence of genes of resistance to different antibiotics can be transferred to different microorganisms independently, with the forming of new resistant strains, which are differing in resistance to natural antimicrobial organic acidcs as well as their synthetic derivatives and it has a significant ecological and medical importance.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"14 1","pages":"64 - 72"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91160318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Modern research from the last years show that some vitamins have changed in their role of maintaining a healthy life. The paper presents information about the concept of vitamins and possible sources of vitamins from marine algae found in the Black Sea. The existence of vitamins in green algae from Enteromorpha and Cladophora species were identified through spectral analyzes in IR.
{"title":"The Identification of Vitamins from Marine Algae of Black Sea by Spectrodcopic Methods","authors":"Emin Cadâr, A. Tomescu","doi":"10.26417/832lpl20d","DOIUrl":"https://doi.org/10.26417/832lpl20d","url":null,"abstract":"Modern research from the last years show that some vitamins have changed in their role of maintaining a healthy life. The paper presents information about the concept of vitamins and possible sources of vitamins from marine algae found in the Black Sea. The existence of vitamins in green algae from Enteromorpha and Cladophora species were identified through spectral analyzes in IR.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"103 16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77804018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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