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SVILUPPO SOSTENIBILE: GLI OBIETTIVI DELLE NAZIONI UNITE 2015-2030 可持续发展:联合国2015-2030年目标
Pub Date : 2021-03-18 DOI: 10.4081/INCONTRI.2021.714
Enrica Chiappero
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引用次数: 0
OBIETTIVO 10a. RIDURRE LE DISUGUAGLIANZE ALL’INTERNO E FRA LE NAZIONI 第十次目标。减少国家内部和国家间的不平等
Pub Date : 2021-03-18 DOI: 10.4081/INCONTRI.2021.716
Renata Lenti Targetti
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引用次数: 0
GREEN ECONOMY: LA MIGLIORE RISPOSTA ALLA CRISI, UNA SFIDA PER IL FUTURO 绿色经济:应对危机的最佳方式,对未来的挑战
Pub Date : 2021-03-18 DOI: 10.4081/INCONTRI.2021.718
Ermete Realacci
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引用次数: 0
GLI OBIETTIVI DI SVILUPPO SOSTENIBILE AI TEMPI DELLA PANDEMIA 大流行时期的可持续发展目标
Pub Date : 2021-03-18 DOI: 10.4081/INCONTRI.2021.719
S. Veca
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引用次数: 0
OBIETTIVO 10b. PROMUOVERE LA GIUSTIZIA E L’INCLUSIONE SOCIALE 10b目标。促进正义和社会包容
Pub Date : 2021-03-18 DOI: 10.4081/INCONTRI.2021.717
R. Artoni
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引用次数: 0
GLI OBIETTIVI DI SVILUPPO SOSTENIBILE DELLE NAZIONI UNITE 2015-2030 联合国2015-2030年可持续发展目标
Pub Date : 2021-03-18 DOI: 10.4081/INCONTRI.2021.712
A. Martinelli
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引用次数: 0
LA SINDROME METABOLICA
Pub Date : 2020-12-31 DOI: 10.4081/INCONTRI.2020.627
Carlo Maria Rotella
As the word itself says, a syndrome is not a disease in its own right, but a set of various diseases that coexist in the same individual. Metabolic Syndrome (MS) was first described many years ago, but it came back to the fore again in 1998 by Alberti and Zimmet who tried to give it a more modern definition. It was then in 2001 that Grundy defined simpler and easily determinable criteria in an outpatient setting. When compared with other diagnostic criteria, such as those of the International Diabetes Federation, it was seen that the 2001 criteria had a higher specificity, even if a lower sensitivity, and therefore were those to be preferred in identifying the truly affected patients by SM. The MS criteria actually represent the most important modifiable cardiovascular risk factors, as they are related to Visceral Obesity and Insulin Resistance (IR), which proceed in parallel in individuals. Visceral adipose tissue is a true endocrine organ that produces many hormone-acting substances called Adipokines. These are the main responsible for the establishment and maintenance of the IR, as well as for hypertension, hypertriglyceridemia and blood coagulation alterations. In fact, in patients with MS, excess adipose tissue is almost always accompanied by a decrease in muscle tissue, i.e. a state of sarcopenia. Muscle tissue also produces cytokines and hormonal substances with protective function against the cardiovascular risk factors present in the MS criteria, the lack of muscle mass reduces the production of these molecules and therefore the presence of sarcopenia further worsens the entity of the cardiovascular risk. There are other additional factors, other than those present in the classifications, which can play an important role in MS. Current scientific evidence shows a correlation between vitamin D and risk, incidence, number and severity of the components of the Metabolic Syndrome and its complications (DM2 and cardiovascular diseases). About 90% of obese and diabetic patients have a more or less serious deficiency of vitamin D, and this condition has been directly correlated with the dysfunctional adiposity index (LAP index). The other condition that is frequently observed in MS patients is hyperuricemia and this seems mainly due to the high consumption of fructose in the diet. The consequences of fructose metabolism can lead to a decrease in intracellular ATP, an increase in uric acid production, oxidative stress, inflammation, and an increase in lipid synthesis, which are associated with endothelial dysfunction. The latter represents an early manifestation of vascular disease and a stimulus for the development of Metabolic Cardiorenal Syndrome.
正如这个词本身所说,综合症本身并不是一种疾病,而是在同一个人身上共存的一系列不同疾病。代谢综合征(MS)在许多年前首次被描述,但在1998年,Alberti和Zimmet试图给它一个更现代的定义,它又回到了人们的视野。2001年,Grundy在门诊环境中定义了更简单、更容易确定的标准。与其他诊断标准(如国际糖尿病联合会的诊断标准)相比,2001年的诊断标准具有更高的特异性,尽管敏感性较低,因此是识别SM真正影响患者的首选标准。MS标准实际上代表了最重要的可改变的心血管危险因素,因为它们与内脏肥胖和胰岛素抵抗(IR)有关,两者在个体中并行进行。内脏脂肪组织是一个真正的内分泌器官,它产生许多称为脂肪因子的激素作用物质。这些主要负责IR的建立和维持,以及高血压、高甘油三酯血症和血液凝固改变。事实上,在多发性硬化症患者中,脂肪组织的过剩几乎总是伴随着肌肉组织的减少,即肌肉减少的状态。肌肉组织还会产生对MS标准中存在的心血管危险因素具有保护功能的细胞因子和激素物质,肌肉质量的缺乏减少了这些分子的产生,因此肌肉减少症的存在进一步恶化了心血管风险的存在。除了分类中存在的因素外,还有其他其他因素可以在ms中发挥重要作用。目前的科学证据表明,维生素D与代谢综合征及其并发症(DM2和心血管疾病)组成部分的风险、发病率、数量和严重程度之间存在相关性。约90%的肥胖和糖尿病患者或多或少存在严重的维生素D缺乏,这种情况与功能失调肥胖指数(LAP指数)直接相关。在多发性硬化症患者中经常观察到的另一种情况是高尿酸血症,这似乎主要是由于饮食中果糖的大量消耗。果糖代谢的后果可导致细胞内ATP减少、尿酸生成增加、氧化应激、炎症和脂质合成增加,这些都与内皮功能障碍有关。后者是血管疾病的早期表现,是代谢性心肾综合征发展的刺激因素。
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引用次数: 0
INTRODUZIONE AL CONVEGNO 会议简介
Pub Date : 2020-04-23 DOI: 10.4081/incontri.2020.645
F. Cavagnini, L. Martini
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引用次数: 0
LA FAME DENTRO IL CERVELLO 大脑中的饥饿
Pub Date : 2020-04-20 DOI: 10.4081/incontri.2020.629
Vittorino Andreoli
The brain has two characteristics in relation to nutrition. The first is to consume 20% of the energy introduced, although it represents only 2% of body weight. In childhood, consumption can reach 60%. The second peculiarity concerns the regulation of the sense of hunger, satiety and thirst. Biological mechanisms for this purpose are reported. Particular attention is given to the function of emotions and feelings on this regulatory system, and the influence of social habits and cultures of different countries. These elements can affect pathologies such as anorexia and bulimia.
大脑在营养方面有两个特点。第一种是消耗摄入的能量的20%,尽管它只占体重的2%。在儿童时期,摄入量可达60%。第二个特性涉及对饥饿、饱足和口渴感的调节。报道了这一目的的生物学机制。特别关注情绪和感觉在这一调节系统中的作用,以及不同国家的社会习惯和文化的影响。这些因素会影响诸如厌食症和贪食症等疾病。
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引用次数: 0
LO STORICO 历史学家
Pub Date : 2020-03-04 DOI: 10.4081/incontri.2019.612
F. Piva
Professor Martini and I shared an interest in the history of the twentieth century, with particular attention to the birth and development of fascist and nazi regimes. We soon adopted the use to exchange books on this issue; whenever possible we adopted the use to accompany the attendance to congresses to visits to sites that could help us to improve our knowledge of historical events.
Martini教授和我都对二十世纪的历史感兴趣,特别关注法西斯和纳粹政权的诞生和发展。我们很快就采取了在这个问题上交换书籍的做法;只要有可能,我们就会在参加大会的同时,参观一些有助于提高我们对历史事件的认识的地点。
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引用次数: 0
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Istituto Lombardo - Accademia di Scienze e Lettere - Incontri di Studio
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