Erdem Ilgün, Ö. Akyürek, A. Kalkan, Fethi Demir, M. Demirayak, M. Bilgi
Objective:We aimed at contributing to the understanding of the pathophysiology of Fibromyalgia (FM) by measuring neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR), which are the systemic inflammatory response (SIR) markers in patients with fibromyalgia.Method:The study population consisted of 70 patients newly diagnosed with FM (mean (SD) age: 43.9 (±9.8) years, 80% were female) and 52 healthy volunteers (mean (SD) age: 43.4 (±10.4) years, 76.9% were female). American College of Rheumatology-ACR 1990 criteria regarding the evaluation of widespread pain and tender points were used for the diagnosis of FM. Demographic characteristics, anthropometrics and laboratory findings were used to make comparisons between patient and control groups.Results:PLR was 128.0 (±40.2) in the patient group while it was 110.5 (±33.6) in the control group and the difference was found to be significant (p=0.03). NLR was similar in both groups. The tender point count was significantly higher in the patient group (p<0.001) whereas there was a negative correlation between the tender point count and the lymphocyte count (r= -0.200; p=0.020) and a strong positive correlation with PLR (r=0.022; p=0.001).Conclusion:Our findings indicate that NLR levels were similar in both groups while the PLR values of the FM patients were found to be significantly higher than those of the control group and there was a positive correlation between PLR and the tender point count.
{"title":"Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio in Fibromyalgia","authors":"Erdem Ilgün, Ö. Akyürek, A. Kalkan, Fethi Demir, M. Demirayak, M. Bilgi","doi":"10.15197/EJGM.1525","DOIUrl":"https://doi.org/10.15197/EJGM.1525","url":null,"abstract":"Objective:We aimed at contributing to the understanding of the pathophysiology of Fibromyalgia (FM) by measuring neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR), which are the systemic inflammatory response (SIR) markers in patients with fibromyalgia.Method:The study population consisted of 70 patients newly diagnosed with FM (mean (SD) age: 43.9 (±9.8) years, 80% were female) and 52 healthy volunteers (mean (SD) age: 43.4 (±10.4) years, 76.9% were female). American College of Rheumatology-ACR 1990 criteria regarding the evaluation of widespread pain and tender points were used for the diagnosis of FM. Demographic characteristics, anthropometrics and laboratory findings were used to make comparisons between patient and control groups.Results:PLR was 128.0 (±40.2) in the patient group while it was 110.5 (±33.6) in the control group and the difference was found to be significant (p=0.03). NLR was similar in both groups. The tender point count was significantly higher in the patient group (p<0.001) whereas there was a negative correlation between the tender point count and the lymphocyte count (r= -0.200; p=0.020) and a strong positive correlation with PLR (r=0.022; p=0.001).Conclusion:Our findings indicate that NLR levels were similar in both groups while the PLR values of the FM patients were found to be significantly higher than those of the control group and there was a positive correlation between PLR and the tender point count.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87500220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Méndez-Martínez, M. García-Carrasco, C. Mendoza-Pinto, E. García-Cano, Á. Montiel-Jarquín
Objective:To determine early or late post surgical complications secondary to simple and complex gastroschisis.Methods:The association between early (acid-base disorders, electrolyte disturbances and presence of hypoalbuminemia), and late postnatal complications (respiratory, gastrointestinal, infectious) was investigated in newborn.Results:42 children, 54.8% male, 73.8% premature, average gestational age of 35.6±2.5 gestational weeks of age (GWA), weight 2147±537gr, they have a NICU stay of 192±14 days, PNT of 19.2±20 days, mortality of 26.2%. The frequent immediate postoperative complications were base-acid imbalance; the metabolic acidosis was associated to simple gastroschisis (p=0.049). The complex gastroschisis was associated to necrotizing enterocolitis (p=0.025), surgical closure type (p=0.003), reinterventions (p=0.025).Conclusion:Acid-Base alterations (76.1%), hypoalbuminemia (59.5%) as early complications and Late sepsis (40.4%), cholestasis (26.1%) as late complications are the most common in patients with Gasthoschisis.
{"title":"Surgical Complications of Simple and Complex Gastroschisis in Newborn","authors":"S. Méndez-Martínez, M. García-Carrasco, C. Mendoza-Pinto, E. García-Cano, Á. Montiel-Jarquín","doi":"10.15197/EJGM.1495","DOIUrl":"https://doi.org/10.15197/EJGM.1495","url":null,"abstract":"Objective:To determine early or late post surgical complications secondary to simple and complex gastroschisis.Methods:The association between early (acid-base disorders, electrolyte disturbances and presence of hypoalbuminemia), and late postnatal complications (respiratory, gastrointestinal, infectious) was investigated in newborn.Results:42 children, 54.8% male, 73.8% premature, average gestational age of 35.6±2.5 gestational weeks of age (GWA), weight 2147±537gr, they have a NICU stay of 192±14 days, PNT of 19.2±20 days, mortality of 26.2%. The frequent immediate postoperative complications were base-acid imbalance; the metabolic acidosis was associated to simple gastroschisis (p=0.049). The complex gastroschisis was associated to necrotizing enterocolitis (p=0.025), surgical closure type (p=0.003), reinterventions (p=0.025).Conclusion:Acid-Base alterations (76.1%), hypoalbuminemia (59.5%) as early complications and Late sepsis (40.4%), cholestasis (26.1%) as late complications are the most common in patients with Gasthoschisis.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72944445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Özgür Bilgin Topçuoğlu, G. Afşar, Sema Sarac, O. Oruc, Tülin Kuyucu
Objective: To evaluate the relationship of mean platelet volume and OSAS severity, in OSAS patients without any vascular risk factors and co-morbidites. Method: The patients files and polysomnographies of OSAS patients who admitted to sleep laboratory between January 1st 2011 and April 1st 2012 have been retrospectively evaluated. Inclusion criteria are to have no vascular risk factors and no co-morbidities, to be a non-smoker, to be older than 18 years of age and not be taking any medications. Patients have been grouped as severe and non-severe OSAS according to their apne- hypopne indices. Mean platelet volume (MPV) of patients in the two groups have been compared. Results: Among 81 patients who met the inclusion criteria, 39.6% of the patients had severe OSAS while 60.4% had non-severe OSAS. MPV in the severe group was 9.05+0.89 (fL), while it was 9.00+0.82 (fL) in the non-severe group. The difference of MPV between two groups was not significant (p:0.800). Conclusion: Controversially with the former studies which declared higher MPV in severe OSAS, our study concludes that when all other risk factors are excluded MPV is not an indicator of severity in OSAS.
{"title":"In the Absence of Co-Morbidities Mean Platelet Volume is not A Severity Indicator in OSAS","authors":"Özgür Bilgin Topçuoğlu, G. Afşar, Sema Sarac, O. Oruc, Tülin Kuyucu","doi":"10.15197/EJGM.1555","DOIUrl":"https://doi.org/10.15197/EJGM.1555","url":null,"abstract":"Objective: To evaluate the relationship of mean platelet volume and OSAS severity, in OSAS patients without any vascular risk factors and co-morbidites. Method: The patients files and polysomnographies of OSAS patients who admitted to sleep laboratory between January 1st 2011 and April 1st 2012 have been retrospectively evaluated. Inclusion criteria are to have no vascular risk factors and no co-morbidities, to be a non-smoker, to be older than 18 years of age and not be taking any medications. Patients have been grouped as severe and non-severe OSAS according to their apne- hypopne indices. Mean platelet volume (MPV) of patients in the two groups have been compared. Results: Among 81 patients who met the inclusion criteria, 39.6% of the patients had severe OSAS while 60.4% had non-severe OSAS. MPV in the severe group was 9.05+0.89 (fL), while it was 9.00+0.82 (fL) in the non-severe group. The difference of MPV between two groups was not significant (p:0.800). Conclusion: Controversially with the former studies which declared higher MPV in severe OSAS, our study concludes that when all other risk factors are excluded MPV is not an indicator of severity in OSAS.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82018453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Management of severe spasticity in spinal cord injured patients is challenging especially when associated with bilateral hip joint subluxation. A 22-year-old paraplegic girl presented with very severe lower limbs spasticity and unstable hips. She was treated with botulinum toxin a injections to her lower limb muscles. This method of treatment was shown to be effective in a case of severe spasticity with unstable hips.
{"title":"Challenges in Managing Severe Lower Limb Spasticity Associated with Bilateral Hip Joints Subluxation","authors":"O. Htwe, R. I. Hussain, A. S. Naicker","doi":"10.15197/EJGM.1475","DOIUrl":"https://doi.org/10.15197/EJGM.1475","url":null,"abstract":"Management of severe spasticity in spinal cord injured patients is challenging especially when associated with bilateral hip joint subluxation. A 22-year-old paraplegic girl presented with very severe lower limbs spasticity and unstable hips. She was treated with botulinum toxin a injections to her lower limb muscles. This method of treatment was shown to be effective in a case of severe spasticity with unstable hips.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91429830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Aggarwal, D. Jain, S. Pawar, A. Mittal, P. Jain
Sheehan’s syndrome is a rare but potentially serious postpartum complication. Though most common and early symptoms are lactation failure and amenorrhea, some cases might be relatively asymptomatic which are diagnosed in later years when features of hypothyroidism and adrenal insufficiency predominate. Recurrent hypoglycaemia, due to adrenal insufficiency, though described is a rare complication of Sheehan syndrome. Here we report a case of Sheehan syndrome which presented with recurrent episodes of hypoglycaemia,
{"title":"Recurrent Hypoglycaemia: an Uncommon Presentation in Sheehan Syndrome.","authors":"H. Aggarwal, D. Jain, S. Pawar, A. Mittal, P. Jain","doi":"10.15197/EJGM.1457","DOIUrl":"https://doi.org/10.15197/EJGM.1457","url":null,"abstract":"Sheehan’s syndrome is a rare but potentially serious postpartum complication. Though most common and early symptoms are lactation failure and amenorrhea, some cases might be relatively asymptomatic which are diagnosed in later years when features of hypothyroidism and adrenal insufficiency predominate. Recurrent hypoglycaemia, due to adrenal insufficiency, though described is a rare complication of Sheehan syndrome. Here we report a case of Sheehan syndrome which presented with recurrent episodes of hypoglycaemia,","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83244807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nureddin Yüzkat, L. Soyoral, M. B. Çeğin, B. Özkan, U. Goktas
Spinal anesthesia is a regional anesthetic technique applied by the anesthesiologist, more than a hundred years. The growing popularity of ambulatory surgical procedures have led to more frequent use of spinal anesthesia. This is an anesthetic technique which enhances the satisfaction of the patient and surgeon with this aspect. Chordoma is a rare, slow growing primary malignant tumor of the axial skeleton. It is seen at sacrum and skull base in the spine especiallay sacrococcygeal area (%50). In this paper, we presented a rare case of sacral chordoma up our spinal anesthesia. Perioperative potential risks can be minimized by close monitoring and good preoperative evaluation. Thus; anesthesic technique which even thought as an unappropriate method can be prefered and we believe that diagnosis can remain in the secondary plan in this decision.
{"title":"The Role of Surgical Diagnosis in The Choice of Anesthetic Technique","authors":"Nureddin Yüzkat, L. Soyoral, M. B. Çeğin, B. Özkan, U. Goktas","doi":"10.15197/EJGM.1458","DOIUrl":"https://doi.org/10.15197/EJGM.1458","url":null,"abstract":"Spinal anesthesia is a regional anesthetic technique applied by the anesthesiologist, more than a hundred years. The growing popularity of ambulatory surgical procedures have led to more frequent use of spinal anesthesia. This is an anesthetic technique which enhances the satisfaction of the patient and surgeon with this aspect. Chordoma is a rare, slow growing primary malignant tumor of the axial skeleton. It is seen at sacrum and skull base in the spine especiallay sacrococcygeal area (%50). In this paper, we presented a rare case of sacral chordoma up our spinal anesthesia. Perioperative potential risks can be minimized by close monitoring and good preoperative evaluation. Thus; anesthesic technique which even thought as an unappropriate method can be prefered and we believe that diagnosis can remain in the secondary plan in this decision.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81333218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Erboğa, Yeliz Bozdemir Donmez, U. Sener, Z. Erboğa, C. Aktas, M. Kanter
Objective: Doxorubicin (DOX) is a highly effective anti-cancer drug with limited clinical use due to its serious cardiotoxicity. Urtica dioica L. seeds (UD), have been widely used in folk medicine, particularly in the therapy for advanced cancer patients, possesses a potent anti-oxidant properties. The goal of present study was to investigate the cardioprotective effects of UD on DOX-induced cardiotoxicity. Method: The rats in the UD treated group were given intraperitoneally 2 ml/kg UD. To induce cardiotoxicity, 30 mg/kg DOX was injected intraperitoneally by a single dose and the rats were sacrificed after 48 h. Results: The present study revealed for the first time a protective role of UD against DOXinduced cardiotoxicity. UD therapy significantly protected against DOXinduced myocardial damage which was characterized by conduction abnormalities, vacuolization, inflammatory cell infiltration, hemorrhag es, and myofibrillar disarrangement. As indicators of oxidative stress, DOX caused significantly increase lipid peroxidation and reduction in activities of antioxidant enzymes; superoxide dismutase, glutathione peroxidase, and catalase. UD treatment significantly attenuated DOXinduced oxidative injury. Conclusion: The present study showed that UD might be a suitable cardioprotector against toxic effects of DOX.
{"title":"Effect of Urtica Dioica against Doxorubicin-InducedCardiotoxicity in Rats through Suppression ofHistological Damage, Oxidative Stress and LipidPeroxidation","authors":"M. Erboğa, Yeliz Bozdemir Donmez, U. Sener, Z. Erboğa, C. Aktas, M. Kanter","doi":"10.15197/EJGM.1567","DOIUrl":"https://doi.org/10.15197/EJGM.1567","url":null,"abstract":"Objective: Doxorubicin (DOX) is a highly effective anti-cancer drug with limited clinical use due to its serious cardiotoxicity. Urtica dioica L. seeds (UD), have been widely used in folk medicine, particularly in the therapy for advanced cancer patients, possesses a potent anti-oxidant properties. The goal of present study was to investigate the cardioprotective effects of UD on DOX-induced cardiotoxicity. Method: The rats in the UD treated group were given intraperitoneally 2 ml/kg UD. To induce cardiotoxicity, 30 mg/kg DOX was injected intraperitoneally by a single dose and the rats were sacrificed after 48 h. Results: The present study revealed for the first time a protective role of UD against DOXinduced cardiotoxicity. UD therapy significantly protected against DOXinduced myocardial damage which was characterized by conduction abnormalities, vacuolization, inflammatory cell infiltration, hemorrhag es, and myofibrillar disarrangement. As indicators of oxidative stress, DOX caused significantly increase lipid peroxidation and reduction in activities of antioxidant enzymes; superoxide dismutase, glutathione peroxidase, and catalase. UD treatment significantly attenuated DOXinduced oxidative injury. Conclusion: The present study showed that UD might be a suitable cardioprotector against toxic effects of DOX.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76691230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Intussusception is the most common intestinal obstruction among infants and young children. Most of the pediatric cases are ileocecal. Isolated small bowel intussusception accounts for fewer than 10% of all pediatric cases. We reported a previously healthy 3-year-old child who presented with multiple ileo-ileal intussusceptions. Preoperatively, diagnosis made by ultrasonography. During surgery, edematous and dilated small bowel loops with four intussusceptions were found. Ileocecal junction was normal. Our experience shows that the rare entity of multiple intussusceptions with no obviously causative agent may present in pediatric patients.
{"title":"Multiple Ileo-ileal Intussusceptions in a 3-Year-Old Child","authors":"B. Kızılyıldız, B. Beger, B. Sönmez, K. Karaman","doi":"10.15197/EJGM.1454","DOIUrl":"https://doi.org/10.15197/EJGM.1454","url":null,"abstract":"Intussusception is the most common intestinal obstruction among infants and young children. Most of the pediatric cases are ileocecal. Isolated small bowel intussusception accounts for fewer than 10% of all pediatric cases. We reported a previously healthy 3-year-old child who presented with multiple ileo-ileal intussusceptions. Preoperatively, diagnosis made by ultrasonography. During surgery, edematous and dilated small bowel loops with four intussusceptions were found. Ileocecal junction was normal. Our experience shows that the rare entity of multiple intussusceptions with no obviously causative agent may present in pediatric patients.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91392066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective:The incidence of tracheobronchial aspirations of foreign bodies in adults is lower than in children. In this article, we aimed to present our experience in tracheobronchial aspiration of foreign bodies in adults during 25-years.Methods:From January 1990 to January 2015, 122 patients older than 16 years with suspected tracheobronchial aspiration of foreign body were included in this study. Patients’ data cards were retrospectively assessed according to age, gender, clinical symptoms and physical examination findings, localization and type of foreign body, radiologic findings and therapeutic options.Results:Ninety-six of the patients were female (78.7%) and 26 were male (21.3%). The age range was 17-70 years and mean age was 30.3 years. Rigid bronchoscopy was performed in all patients. Foreign bodies were seen in 112 patients (91.8%). Foreign bodies were extracted by rigid bronchoscopy in 109 patients. Thoracotomy and pneumotomy were performed in the remaining 3 patients. The most common foreign body was pin (83%). The chief symptom was cough (100%). The most common anatomic location of foreign bodies was right bronchial system (60.7%). The main radiologic finding was radiopaque image of the related foreign body (88.4%). Right lower lobectomy was performed in two patients because of bronchiectasis.Conclusion:If tracheobronchial aspirations of foreign bodies are not treated in early period, irreversible and suppurative lung diseases may occur as results of aspirations in later years. The education of societies about this subject is principal precaution in reducing the frequency of tracheobronchial aspirations of foreign bodies.
{"title":"Tracheobronchial Foreign Bodies Aspirations in Adults: A 25-Years Experience","authors":"B. Altuntas, Y. Aydın, A. Eroğlu","doi":"10.15197/EJGM.1506","DOIUrl":"https://doi.org/10.15197/EJGM.1506","url":null,"abstract":"Objective:The incidence of tracheobronchial aspirations of foreign bodies in adults is lower than in children. In this article, we aimed to present our experience in tracheobronchial aspiration of foreign bodies in adults during 25-years.Methods:From January 1990 to January 2015, 122 patients older than 16 years with suspected tracheobronchial aspiration of foreign body were included in this study. Patients’ data cards were retrospectively assessed according to age, gender, clinical symptoms and physical examination findings, localization and type of foreign body, radiologic findings and therapeutic options.Results:Ninety-six of the patients were female (78.7%) and 26 were male (21.3%). The age range was 17-70 years and mean age was 30.3 years. Rigid bronchoscopy was performed in all patients. Foreign bodies were seen in 112 patients (91.8%). Foreign bodies were extracted by rigid bronchoscopy in 109 patients. Thoracotomy and pneumotomy were performed in the remaining 3 patients. The most common foreign body was pin (83%). The chief symptom was cough (100%). The most common anatomic location of foreign bodies was right bronchial system (60.7%). The main radiologic finding was radiopaque image of the related foreign body (88.4%). Right lower lobectomy was performed in two patients because of bronchiectasis.Conclusion:If tracheobronchial aspirations of foreign bodies are not treated in early period, irreversible and suppurative lung diseases may occur as results of aspirations in later years. The education of societies about this subject is principal precaution in reducing the frequency of tracheobronchial aspirations of foreign bodies.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80206113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lactic acidosis is a known complication of long-term linezolid therapy. We present a case where lactic acidosis developed only after 2 doses of linezolid. A review of literature revealed only 2 cases in which lactic acidosis developed soon after linezolid treatment was commenced. Both patients had underlying immunocompromising conditions. Our patient, like the previous 2 reports had an underlying immunocompromising condition – acute myeloid leukemia. It seems that linezolid has the propensity of inducing lactic acidosis soon after its commencement in immunocompromised patients.
{"title":"Linezolid-induced Lactic Acidosis","authors":"H. Rehman","doi":"10.15197/EJGM.1439","DOIUrl":"https://doi.org/10.15197/EJGM.1439","url":null,"abstract":"Lactic acidosis is a known complication of long-term linezolid therapy. We present a case where lactic acidosis developed only after 2 doses of linezolid. A review of literature revealed only 2 cases in which lactic acidosis developed soon after linezolid treatment was commenced. Both patients had underlying immunocompromising conditions. Our patient, like the previous 2 reports had an underlying immunocompromising condition – acute myeloid leukemia. It seems that linezolid has the propensity of inducing lactic acidosis soon after its commencement in immunocompromised patients.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87110100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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