Advances in knowledge have contributed to the global understanding of nutritional patterns' influence on mental health. The aim was to determine the impact of a high-symbiotic diet on cardio-metabolic and psychopathological outcomes in schizophrenia.
A randomised clinical trial (two-arm, double-blind, balanced-block, six-month intervention) was conducted on 50 individuals diagnosed with schizophrenia spectrum disorder. The control group received conventional dietary advice individually. The intervention group received intensive dietary advice based on the increasing consumption of food with high symbiotic content (fermented foods, whole grains, green leafy vegetables and fruits high in dietary fibre, among others). Researchers collected data on cardiovascular and psychopathological status at baseline, three and six months. In addition, anthropometric parameters were analysed monthly.
Forty-four subjects were analysed. Compared to the control group, the intervention group demonstrated improvements in the PANSS-GP subscale and the PSP scale scores over 3–6 months (p < 0.05). Anthropometric values were decreased in all the variables (p < 0.05). Systolic blood pressure decreased between 3 and 6 months (p = 0.049).
Nutrition education for increasing the consumption of foods with high symbiotic content has positively impacted the cardio-metabolic and psychopathological profile in patients with schizophrenia spectrum disorders. In addition, advanced practice mental health nurses have been shown to play a prominent role in developing nutrition education and promoting healthy lifestyles in these patients.
This study employed the Delphi method to identify the ideal characteristics of a clozapine adverse drug reaction (ADR) scale, engaging 34 clozapine specialists at the 6th NEMEA meeting. Participants emphasized the integration of clinician-rated (CROM) and patient-rated (PROM) outcomes in the scale, aiming for a balance between comprehensiveness and practicality. Key consensus points included the inclusion of specific ADRs like somnolence, sialorrhea, and compulsivity, while metabolic complications were considered less relevant. This research highlights the need for a practical, patient-inclusive tool for monitoring clozapine ADRs, reflective of both clinical expertise and patient experiences in managing treatment-resistant schizophrenia.
Currently, there is a growing interest in exploring the underlying processes that explain how and why therapeutic approaches work. This study aims to investigate whether Mindfulness-Based Cognitive Therapy (MBCT) can enhance direct experience compared to a control intervention. 72 women diagnosed with eating disorders were assigned to either MBCT or a control treatment. Pre- and post-intervention, participants were asked to eat an orange slice and write down thoughts about the eating experience, classifying the focus of each experience as either experiential or analytical. Compared with the control group, participants who underwent MBCT showed a statistically significant increase in direct experience.

