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FORCED EXPRESSION OF BCL-2 AND BCL-xL BY NOVEL WATER-SOLUBLE FULLERENE, C60(GLUCOSAMINE)6, REDUCES RENAL ISCHEMIA/REPERFUSION-INDUCED OXIDATIVE STRESS 新型水溶性富勒烯C60(葡萄糖胺)6强制表达BCL-2和BCL-xL,减少肾缺血/再灌注引起的氧化应激
Pub Date : 2001-02-26 DOI: 10.1081/FST-100000167
C. Chien, Chau‐Fong Chen, S. Hsu, L. Chiang, M. Lai
Apoptosis induced by oxidative stress, especially reactive oxygen species, resulting from ischemia/reperfusion would lead to organ dysfunction. C60(glucosamine)6, a water-soluble fullerene with strong free radical scavenging activity, was applied to evaluate its effect on renal ischemia/reperfusion-induced apoptosis formation and superoxide generation. C60(glucosamine)6 pretreatment, but not posttreatment, significantly reduced renal ischemia/reperfusion-induced apoptosis and superoxide generation and, consequently, ameliorated renal hemodynamic effects. Up-regulation in bcl-2 and bcl-xL of the rat kidney was evident in C60(glucosamine)6 pretreated, posttreated, and nontreated groups. However, exaggerated forced expression of bcl-2 and bcl-xL was found in the C60(glucosamine)6 pretreated group. Our results conclude that forced expression of bcl-2 and bcl-xL by the novel water-soluble fullerene, C60(glucosamine)6, can reduce renal ischemia/ reperfusion-induced oxidative stress.
缺血/再灌注引起的氧化应激,尤其是活性氧诱导的细胞凋亡可导致器官功能障碍。C60(glucosamine)6是一种具有较强自由基清除活性的水溶性富勒烯,研究其对肾缺血/再灌注诱导的细胞凋亡形成和超氧化物生成的影响。C60(葡萄糖胺)6预处理,而不是后处理,显著减少肾缺血/再灌注诱导的细胞凋亡和超氧化物的产生,从而改善肾脏血流动力学效应。大鼠肾bcl-2和bcl-xL在C60(葡萄糖胺)6预处理、后处理和未处理组均明显上调。而在C60(葡萄糖胺)6预处理组,bcl-2和bcl-xL的强迫表达明显升高。我们的研究结果表明,新型水溶性富勒烯C60(葡萄糖胺)6强制表达bcl-2和bcl-xL可以减轻肾缺血/再灌注引起的氧化应激。
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引用次数: 10
SIMULTANEOUS DETERMINATION OF C60 AND C70 FULLERENES BY A SPECTROPHOTOMETRIC METHOD 分光光度法同时测定c60和c70富勒烯
Pub Date : 2001-02-26 DOI: 10.1081/FST-100000169
B. Çiçek, A. Kenar, H. Nazır
In all fullerene-producing systems, reaction products were black soot extracts reported to contain a 5–25% fullerene mixture. Toluene extraction of the soot results in a solution of C60, C70, and higherc fullerenes. Without separation, absolute determination of the contents is not possible, leaving the researcher to comment only on the C60/C70 ratio of the solution. High-performance liquid chromatography, nuclear magnetic resonance, and scanning tunneling microscopy imaging techniques were reported in the literature for determining the C60/C70 ratio of the mixtures. These methods require tedious experiments and produce slightly differing results as well. In this communication, a new and relatively quick method is proposed for the simultaneous determination of the yields of C60 and C70 (not the ratio) in fullerene-containing solutions by ultraviolet-visible spectrophotometric analysis.
在所有的富勒烯生成系统中,反应产物是含有5-25%富勒烯混合物的黑烟提取物。烟尘的甲苯萃取得到C60、C70和更高的富勒烯的溶液。不进行分离,就不可能对内容物进行绝对测定,使研究人员只能对溶液的C60/C70比率进行评价。高效液相色谱、核磁共振和扫描隧道显微镜成像技术被文献报道用于测定混合物的C60/C70比。这些方法需要繁琐的实验,产生的结果也略有不同。本文提出了一种相对快速的紫外-可见分光光度法同时测定含富勒烯溶液中C60和C70的产率(而不是比值)的新方法。
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引用次数: 10
ENDOFULLERENE POLARIZATION AND DYNAMICS IN ELECTRIC FIELD: THE QUASICLASSIC APPROACH 电场中的内富勒烯极化和动力学:准经典方法
Pub Date : 2001-02-26 DOI: 10.1081/FST-100000159
Yu. K. Golicov, L. N. Gall’, Z. Z. Latypov, N. Gall’
The quasiclassical approach has been used to calculate a fullerene and an endofullerene molecular interaction with electric fields. A physical model for an endofullerene molecular polarizability in electric fields has been developed and equations describing the interaction have been deduced.
用准经典方法计算了富勒烯和内富勒烯分子与电场的相互作用。建立了电场作用下富勒烯分子极化率的物理模型,推导了描述相互作用的方程。
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引用次数: 1
RAPID ASSESSMENT OF THE FREE RADICAL SCAVENGING PROPERTY OF FULLERENES 富勒烯自由基清除性能的快速评价
Pub Date : 2001-02-26 DOI: 10.1081/FST-100000161
K. Geckeler, S. Samal
The free radical scavenging property of fullerenes and their derivatives is demonstrated by a facile color reaction of C60 with the 1,1-diphenyl-2-picryl hydrazyl radical. A rapid test by simply monitoring the reaction using ultraviolet-visible spectroscopy is suggested.
富勒烯及其衍生物与1,1-二苯基-2-吡啶酰肼自由基的显色反应证明了富勒烯及其衍生物的自由基清除能力。提出了一种简单监测反应的紫外-可见光谱快速检测方法。
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引用次数: 18
EFFECT OF RESIDENCE TIME ON FULLERENE YIELD 停留时间对富勒烯产率的影响
Pub Date : 2001-02-26 DOI: 10.1081/FST-100000165
B. Çiçek
Although there exists no general agreement on mechanistic pathways for fullerene formation, there are some reasonable schemes in the literature explaining most of the features. However, as far as the existing production processes and the final yields are concerned, not the formation but rather chemical stabilization of the relatively hot products was more influence on the final production yield. A continuous helium jet was blown into the reactive zone by a quartz microprobe located 20 mm away from the arc to enhance rapid removal of the products from the high temperature zone. Decreased residence times appear to improve production efficiency.
虽然对富勒烯形成的机制途径没有普遍的共识,但文献中有一些合理的方案可以解释大多数特征。但就现有的生产工艺和最终产率而言,对最终产率影响较大的不是相对热产物的形成,而是相对热产物的化学稳定性。在距离电弧20mm处的石英微探针向反应区吹入连续的氦射流,以增强产物从高温区快速移除的能力。减少停留时间可以提高生产效率。
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引用次数: 3
A STUDY ON THE THERMAL STABILITY OF THE PHOTOPOLYMER, THE OZOPOLYMER, AND THE PHOTOCHLORINATED DERIVATIVE OF C60 FULLERENE 光聚合物、臭氧聚合物及c60富勒烯的光氯化衍生物的热稳定性研究
Pub Date : 2001-02-26 DOI: 10.1081/FST-100000164
F. Cataldo
The thermal stability of the C60 photopolymer, the C60 ozo-polymer, and photochlorinated C60 was studied by thermogravimetric analysis (TGA) ultraviolet-visible (UV-vis) and TGA-differential thermal analysis techniques up to 950°C in comparison to graphite and pure C60. The ozopolymer was found to be the least stable material followed by C60Cl x . The resulting residual carbonaceous matter formed by the decomposition of the photopolymer and the ozopolymer has been studied by Fourier transform-infrared (FTIR) spectroscopy and has been found to be completely comparable to carbon black. The thermal decomposition of the C60 photopolymer prepared in solution yields negligible amounts of C60. The main product is carbon black.
采用热重分析(TGA)、紫外可见分析(UV-vis)和差热分析(TGA -差热分析)技术研究了C60光聚合物、C60臭氧聚合物和光氯化C60在950℃下的热稳定性,并与石墨和纯C60进行了比较。臭氧聚合物是最不稳定的材料,其次是c60clx。通过傅里叶变换红外光谱(FTIR)研究了光聚合物和臭氧聚合物分解后形成的残余碳质物质,发现其与炭黑完全相当。在溶液中制备的C60光聚合物的热分解产生可忽略不计的C60。主要产品是炭黑。
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引用次数: 11
OPTIMIZATION OF THE ELECTRON IRRADIATION IN THE PRODUCTION OF MoTe2 NANOTUBES MoTe2纳米管生产中电子辐照工艺的优化
Pub Date : 2001-02-26 DOI: 10.1081/FST-100000160
E. Flores, A. Tlahuice, E. Adem, D. Galván
In this paper, we report the study of the production of MoTe2 (molybdenum ditelluride) samples after a high dose of electron irradition. A 2 MeV Van de Graaff accelerator was used to irradiate the sample at the following conditions: 1.3 MeV voltage, 5 μA current, 25 kGy/min dose rate, and 1000 kGy total dosage. These conditions are maintain fixed while the irradiation dosages were changed to 50, 100, 200, and 500 Mrad. The optimization of the dosage used for the production of MoTe2 nanotubes was obtained from the analysis of the samples that were examined in a high-resolution transmission electron microscope. The most efficient production of MoTe2 nanotubes was obtained at the range between 100 and 200 Mrad. A very typical characteristic was obtained for rotated structures with angles of 4, 5, 7, 8, and 12° observed in the diffraction pattern for MoTe2.
本文报道了高剂量电子辐照制备二碲化钼样品的研究。采用2 MeV Van de Graaff加速器,在1.3 MeV电压、5 μA电流、25 kGy/min剂量率、1000 kGy总剂量下辐照样品。当辐照剂量改变为50、100、200和500毫摩尔时,这些条件保持不变。通过高分辨率透射电子显微镜对样品进行分析,获得了用于生产MoTe2纳米管的最佳用量。MoTe2纳米管的最有效生产在100和200 Mrad之间。在MoTe2衍射图中观察到的角度为4、5、7、8和12°的旋转结构具有非常典型的特征。
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引用次数: 6
RADIATION CHEMICAL AND PHOTOPHYSICAL PROPERTIES OF C60(C4H8SO3Na) n IN AQUEOUS SOLUTION: A LASER FLASH PHOTOLYSIS AND PULSE RADIOLYSIS STUDY 水溶液中C60(C4H8SO3Na) n的辐射化学和光物理性质:激光闪光光解和光解脉冲研究
Pub Date : 2001-02-26 DOI: 10.1081/FST-100000163
H. Mohan, D. Palit, L. Chiang, J. Mittal
Optical absorption studies on aqueous solutions of C60(C4H8SO3Na) n (n = 4–6) revealed deviation from the Beer-Lambert law in the 250–350 nm region, which is assigned to the formation of solute aggregates at concentrations higher than 1 × 10−3 mol dm−3. Dynamic light scattering experiments showed aggregates with an average size of ∼100 nm. The solute has a broad weak fluorescence emission (ϕf = 1.8 × 10−3) in the 450–650 nm region, which remained independent of solute concentration. The broad transient absorption band in the 450–900 nm region (ϵ660 = 2170 dm3 mol−1 cm−1), which formed immediately on laser flash photolysis (λex = 355 nm, 35 ps), is assigned to singlet-singlet transition. It decays to a triplet excited state whose absorption is observed to depend strongly on solute concentration. In dilute solutions, an absorption band with λmax = 590 nm is seen, and at high solute concentration a broad absorption in the 500–900 nm region is observed. The eaq − reacts with the solute with a bimolecular rate constant of 1.7 × 108 dm3 mol−1 s−1 and forms weak broad absorption bands at 440, 540, 620, 870, 940, and 1020 nm. Isopropanol radicals also react with the solute with a bimolecular rate constant of 2.3 × 108 dm3 mol−1 s−1 with the formation of a transient optical absorption spectrum similar to that observed on reaction with eaq − and assigned to a solute radical anion. The •H and −OH radicals react with bimolecular rate constants of 3.2 × 109 and 4.4 × 109 dm3 mol−1 s−1, respectively, and form transient absorption bands at 440, 510, and 660 nm. Based on electron transfer studies with suitable electron donor/acceptor substrates, the ranges of the reduction and oxidation potentials of the solute an estimated.
对C60(C4H8SO3Na) n (n = 4-6)水溶液的光学吸收研究表明,在250 ~ 350 nm区域,C60(C4H8SO3Na)溶液在浓度大于1 × 10−3 mol dm−3时,会形成溶质聚集体,从而偏离了Beer-Lambert定律。动态光散射实验显示,聚集体的平均尺寸为~ 100 nm。溶质在450 ~ 650 nm范围内具有较宽的弱荧光发射(ϕf = 1.8 × 10−3),且与溶质浓度无关。在450 ~ 900 nm区域(ϵ660 = 2170 dm3 mol−1 cm−1),激光闪光光解(λex = 355nm, 35 ps)立即形成了宽的瞬态吸收带,属于单线态-单线态跃迁。它衰变成三重态激发态,其吸收被观察到强烈依赖于溶质浓度。在稀溶液中,观察到λmax = 590 nm的吸收带,在高溶质浓度下,在500-900 nm范围内观察到广泛的吸收。eaq−与溶质反应的双分子速率常数为1.7 × 108 dm3 mol−1 s−1,在440、540、620、870、940和1020 nm处形成微弱的宽吸收带。异丙醇自由基也与溶质反应,双分子速率常数为2.3 × 108 dm3 mol−1 s−1,形成与与eaq−反应相似的瞬态光吸收光谱,并归属于溶质自由基阴离子。•H和- OH自由基反应的双分子速率常数分别为3.2 × 109和4.4 × 109 dm3 mol−1 s−1,并在440、510和660 nm处形成瞬态吸收带。通过对合适的电子供体/受体基底的电子转移研究,估计了溶质的还原电位和氧化电位范围。
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引用次数: 1
TERNARY SYSTEM OF C60 AND C70 WITH 1,2-DIMETHYLBENZENE c60和c70与1,2-二甲苯的三元体系
Pub Date : 2001-02-26 DOI: 10.1081/FST-100000170
E. B. Stukalin, N. V. Avramenko, M. Korobov, R. Ruoff
Differential scanning calorimetry, X-ray, and solubility measurements were used to study phase equilibria in the ternary system C60-C70-1,2-dimethylbenzene up to the boiling point of the solvent. Formation of the two ternary phases was confirmed. Partial solubilities of C60 and C70 were measured and calculated.
用差示扫描量热法、x射线法和溶解度法研究了三元体系c60 - c70 -1,2-二甲苯在溶剂沸点前的相平衡。两个三元相的形成得到了证实。测量和计算了C60和C70的部分溶解度。
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引用次数: 11
The Science and Technology of Carbon Nanotubes K. Tanaka, T. Yamabe, K. Fukui, Eds.: Elsevier Science, Amsterdam, 1999 碳纳米管的科学与技术田中,山部,福井,编。: Elsevier Science,阿姆斯特丹,1999
Pub Date : 2000-11-01 DOI: 10.1080/10641220009351440
Z. Slanina
The contributed volume of fourteen chapters is opened by a remark from one of the editors K. Fukui (1918-1998). The Nobel laureate of 1981 calls nanotubes and fullerenes 'splendid gift' and points out that such developments of mesoscopic scale suggest the possibility to realize the 'Schrodinger-cat states'. The following three chapters treat various essential aspects of carbon nanotubes. M. Yumura deals with synthesis and purification of nanotubes. Their electron diffraction and microscopy is described by S. Amelinckx e t al. The third chapter in this block, written by T. Hanada e t al., discusses electron energy loss spectroscopy as a tool for nanotube structural studies. The group of the next five chapters is devoted to more specific aspects of nanotube structure and behavior. Electronic structure of single-walled nanotubes is analyzed in a theoretical chapter by K. Tanaka e t al. The following chapter from R. Saito et al. deals with phonon structure and Raman effect of single-walled nanotubes. Contribution from H. Ajiki and T. Ando describes behavior of single-walled nanotubes in magnetic fields. M.
该书共有14章,由其中一位编辑福井k(1918-1998)的评论开篇。这位1981年的诺贝尔奖得主称纳米管和富勒烯是“一份绝妙的礼物”,并指出介观尺度的这种发展表明了实现“薛定谔猫态”的可能性。下面三章讨论碳纳米管的各个基本方面。M. Yumura处理纳米管的合成和纯化。他们的电子衍射和显微镜由S. Amelinckx等人描述。本章的第三章由t . Hanada等人撰写,讨论了电子能量损失光谱作为纳米管结构研究的工具。接下来的五章致力于纳米管结构和行为的更具体的方面。K. Tanaka等人在理论章节中分析了单壁纳米管的电子结构。R. Saito等人的下一章讨论了单壁纳米管的声子结构和拉曼效应。H. Ajiki和T. Ando的贡献描述了单壁纳米管在磁场中的行为。M。
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引用次数: 1
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Fullerene Science and Technology
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