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Chronic Conditions and Resilience: Adolescent Health Behaviors in the Midst of the COVID-19 Pandemic in Thailand. 慢性疾病与复原力:泰国 COVID-19 大流行期间的青少年健康行为。
IF 1.4 Q3 PEDIATRICS Pub Date : 2024-09-05 eCollection Date: 2024-01-01 DOI: 10.1177/2333794X241274732
Phatchara Thitamethee, Narueporn Likhitweerawong, Orawan Louthrenoo, Nonglak Boonchooduang

Objective. To assess the impact of chronic illnesses on risk behaviors and psychosocial adjustments among adolescents during the COVID-19 pandemic in Thailand. Methods. A cross-sectional study was conducted between June 2021 and September 2022, including adolescents aged 10 to 18 years. Participants completed the Thai Youth Risk Behavior Survey and the Strengths and Difficulties Questionnaire (SDQ). Data were analyzed using descriptive statistics, Student's t-test, Chi-square test, and logistic regression. Results. Adolescents with chronic illnesses (n = 120) were more likely to exhibit risk behaviors related to violence (38.3%) and mental health issues (18.3%). They also scored higher on total difficulties (mean = 12.23, SD = 5.14) and emotional symptoms (mean = 3.08, SD = 2.45) than the healthy group (n = 120). Conclusion. During the COVID-19 pandemic, adolescents with chronic illnesses in Thailand demonstrated increased risk behaviors related to violence and mental health issues, highlighting the need for tailored interventions.

目的评估泰国 COVID-19 大流行期间慢性病对青少年危险行为和社会心理适应的影响。研究方法在 2021 年 6 月至 2022 年 9 月期间进行了一项横断面研究,研究对象包括 10 至 18 岁的青少年。参与者填写了泰国青少年危险行为调查表和优势与困难问卷(SDQ)。数据分析采用描述性统计、学生 t 检验、卡方检验和逻辑回归。结果患有慢性疾病的青少年(n = 120)更有可能表现出与暴力(38.3%)和心理健康问题(18.3%)相关的危险行为。与健康组(人数=120)相比,他们在总困难(平均值=12.23,标准差=5.14)和情绪症状(平均值=3.08,标准差=2.45)方面的得分也更高。结论在COVID-19大流行期间,泰国患有慢性疾病的青少年表现出更多与暴力和心理健康问题相关的危险行为,这凸显了采取针对性干预措施的必要性。
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引用次数: 0
Early Neonatal Mortality and Predictors in Newborns Admitted to the Neonatal Intensive Care Unit at Public Hospitals in Hadiya Zone, Central Ethiopia: A Retrospective Cohort Study. 埃塞俄比亚中部哈迪亚区公立医院新生儿重症监护室新生儿早期死亡率及预测因素:一项回顾性队列研究。
IF 1.4 Q3 PEDIATRICS Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI: 10.1177/2333794X241275264
Desta Osamo Kelbore, Dejene Ermias Mekango, Tegegn Tadesse Arficho, Bisrat Feleke Bubamo, Desta Erkalo Abame

Background. Despite numerous life-saving measures, neonatal mortality remains high. This research aims to investigate the incidence and predictors of early neonatal mortality among newborns admitted to intensive care units in public hospitals in Hadiya Zone, Ethiopia. Methods. A retrospective cohort study was conducted on 689 neonates admitted to the neonatal intensive care unit. Cox proportional hazard regression by STATA was used. Results. This study followed for 3439 person-days found an incidence rate of 16.9 deaths per 1000 person-days. Birth weight [AHR = 4.4, 95% CI; 1.29, 14.94], APGAR score at the fifth minute 4 to 6 [AHR = 0.42, 95% CI; 0.2, 0.87], hypoglycemia [AHR = 8.1, 95% CI; 2.17, 30.43], no treated with oxygen [AHR = 2.6, 95% CI; 1.1, 5.9], and obstetric complications [AHR = 0.41, 95% CI; 0.18, 0.93] predicted early neonatal mortality. Conclusion. The study revealed a high neonatal mortality rate, necessitating increased focus on oxygen treatment for newborns and improved early diagnosis and treatment of obstetric complications.

背景。尽管采取了许多挽救生命的措施,但新生儿死亡率仍然很高。本研究旨在调查埃塞俄比亚哈迪亚区公立医院重症监护室收治的新生儿中早期新生儿死亡的发生率和预测因素。研究方法对新生儿重症监护室收治的 689 名新生儿进行了回顾性队列研究。采用 STATA 的 Cox 比例危险回归法。结果。这项研究跟踪了 3439 人天,发现每 1000 人天的发病率为 16.9 例死亡。出生体重[AHR = 4.4, 95% CI; 1.29, 14.94]、第 5 分钟 APGAR 评分 4-6 [AHR = 0.42, 95% CI; 0.2, 0.87]、低血糖[AHR = 8.1, 95% CI; 2.17, 30.43]、未使用氧气治疗[AHR = 2.6, 95% CI; 1.1, 5.9]和产科并发症[AHR = 0.41, 95% CI; 0.18, 0.93]预测早期新生儿死亡率。结论研究显示新生儿死亡率较高,因此有必要加强对新生儿氧疗的重视,并改善产科并发症的早期诊断和治疗。
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引用次数: 0
Traumatic Renal Artery Occlusion in Children: A Case Report. 儿童外伤性肾动脉闭塞:病例报告。
IF 1.4 Q3 PEDIATRICS Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI: 10.1177/2333794X241277597
Yacine Zouirech, Abir Manni, Badr Rouijel, Loubna Aqqaoui, Hicham Zerhouni, Houda Oubejja, Mounir Erraji, Fouad Ettayebi

Blunt trauma is a major cause of death in children, with renal arterial injuries occurring in less than 1% of cases. Traumatic renal artery occlusion (RAO) in children is rare and results in the loss of ipsilateral renal perfusion. Clinical signs are often nonspecific, and there is a lack of information on the exact incidence and management outcomes of these rare cases in children. We report a case of unilateral RAO in a 13-year-old boy with polytrauma. He was diagnosed with right RAO and hepatic laceration after a fall. A conservative approach yielded favorable outcomes despite the loss of function in the right kidney. In stable polytrauma patients, prompt diagnosis of RAO is crucial for treatment optimization and potential kidney salvage.

钝性外伤是儿童死亡的主要原因,而肾动脉损伤发生率不到 1%。儿童外伤性肾动脉闭塞(RAO)非常罕见,会导致同侧肾脏失去灌注。临床症状通常没有特异性,而且缺乏有关这些罕见病例在儿童中的确切发病率和治疗结果的信息。我们报告了一例单侧 RAO 病例,患者是一名 13 岁男孩,患有多发性创伤。他在一次摔倒后被诊断为右侧 RAO 和肝裂伤。尽管右肾功能丧失,但保守治疗取得了良好的效果。对于病情稳定的多发性创伤患者,及时诊断 RAO 对于优化治疗和潜在的肾脏挽救至关重要。
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引用次数: 0
Survival Status and Predictors of Mortality Among Pediatrics Burn Victims Admitted to Burn Centers of Addis Ababa Public Hospitals, Ethiopia: A Retrospective Cohort Study. 埃塞俄比亚亚的斯亚贝巴公立医院烧伤中心收治的儿科烧伤患者的生存状况和死亡率预测因素:回顾性队列研究。
IF 1.4 Q3 PEDIATRICS Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI: 10.1177/2333794X241277341
Zerihun Demisse Bushen, Taye Mezgebu Ashine, Girum Sebsibie Teshome, Tewodros Tesfaye Kebede, Tadesse Sahle Adeba

Background. Burn is a major public health problem in pediatric populations worldwide. This study aimed to determine the survival status and predictors of mortality among pediatric burn victims admitted to burn centers in Ethiopia. Methods. A retrospective cohort study was conducted on the patient charts of 412 pediatric patients with burn injuries at burn centers in Addis Ababa from the 1st of January 2016 to the 30th of December 2019. Data was entered into the Epi-Data manager. Then, the data was exported to STATA V-14 for cleaning and analysis. For the analysis, the proportional hazard model was used. After the model fitness test, variables with a P-value of <.25 in the bivariate analysis were fitted to the multivariate analysis. Finally, statistical significance was decided at a P-value of <.05, and the hazard ratio was used to determine the strength of the association. Result. The study reported an overall incidence rate of 2.4 per 1000 child days. Additionally, it revealed that the median hospital length of stay was 25.00 days (95% CI: 21.57, 28.45). During the follow-up period, 8.25% of deaths occurred among pediatric patients with burn injuries. Specifically, having a full-thickness burn (adjusted hazard ratio [AHR] 2.51, 95% CI: 1.12, 5.62) and neck burn (AHR 2.82, 95% CI: 1.04, 7.68) were identified as significant predictors contributing to increased mortality among burn-injured pediatric individuals. Conclusion. The study highlighted significant mortality rates among pediatric patients suffering from burn injuries. Based on the findings a full-thickness burn injury and burns in the neck area are independent predictors of mortality in pediatric burn patients. Based on the identified predictors of mortality in pediatric burn patients, clinicians should prioritize early recognition, prompt intervention, multidisciplinary management, vigilant monitoring, and preventive strategies to optimize outcomes and reduce mortality rates in this vulnerable population.

背景。烧伤是全球儿童群体中的一个主要公共卫生问题。本研究旨在确定埃塞俄比亚烧伤中心收治的小儿烧伤患者的生存状况和死亡率预测因素。研究方法自2016年1月1日至2019年12月30日,对亚的斯亚贝巴烧伤中心收治的412名烧伤儿科患者的病历进行了回顾性队列研究。数据被输入 Epi-Data 管理器。然后,将数据导出到 STATA V-14 中进行清理和分析。分析中使用了比例危险模型。经过模型适配性检验后,P 值为 P 值的变量为结果。研究报告显示,总发病率为每 1000 个儿童日 2.4 例。此外,研究还显示住院时间的中位数为 25.00 天(95% CI:21.57, 28.45)。在随访期间,8.25%的烧伤儿童患者死亡。具体而言,全厚烧伤(调整后危险比 [AHR] 2.51,95% CI:1.12, 5.62)和颈部烧伤(AHR 2.82,95% CI:1.04, 7.68)被认为是导致烧伤儿科患者死亡率增加的重要预测因素。结论该研究强调了烧伤儿科患者的显著死亡率。根据研究结果,全厚烧伤和颈部烧伤是儿科烧伤患者死亡率的独立预测因素。根据已确定的小儿烧伤患者死亡率预测因素,临床医生应优先考虑早期识别、及时干预、多学科管理、警惕监测和预防策略,以优化治疗效果并降低这一弱势群体的死亡率。
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引用次数: 0
Onset of Type I Diabetes Followed by Scleroderma Syndrome in a Child After the COVID-19: A Case Report. 一名儿童在接受 COVID-19 后出现 I 型糖尿病和硬皮病综合征:病例报告
IF 1.4 Q3 PEDIATRICS Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI: 10.1177/2333794X241276356
Ievgeniia Burlaka, Inga Mityuryayeva, Olena Sevastiian, Ivanna Kachula

Morphea, is a chronic inflammatory disease of the dermis and subcutaneous tissue. Research has indicated a connection between morphea and Type I Diabetes (T1D). COVID-19 can cause autoimmune diseases like scleroderma, T1D, systemic lupus erythematosus, and others. A 12-year-old girl with type 1 diabetes who was on insulin therapy was brought into the clinic for a metabolic evaluation. The patient had induration, skin hardness, and cutaneous erythema upon inspection. The onset of T1D was following a mild COVID-19 infection. Signs of morphea merged 3 months after the onset of T1D. Known as "long-term COVID," this sickness phase that follows the acute stage of COVID-19 is most likely the result of autoimmune activation. As this patient under evaluation reveals, COVID-19 has been demonstrated in the literature to cause the production of autoantibodies and to either cause or worsen autoimmune disorders in people who have a genetic susceptibility.

斑秃是一种真皮和皮下组织的慢性炎症性疾病。研究表明,斑皮病与 I 型糖尿病(T1D)有关。COVID-19 可导致硬皮病、T1D、系统性红斑狼疮等自身免疫性疾病。一名患有 1 型糖尿病并正在接受胰岛素治疗的 12 岁女孩被带到诊所进行代谢评估。经检查,患者皮肤有压痛、发硬和皮肤红斑。T1D 是在轻度 COVID-19 感染后发病的。在 T1D 发病 3 个月后,白斑病的症状合并出现。被称为 "长期 COVID",COVID-19 急性期之后的这一疾病阶段很可能是自身免疫激活的结果。正如这位正在接受评估的患者所揭示的那样,文献已证实 COVID-19 会导致自身抗体的产生,并引起或加重具有遗传易感性的人的自身免疫性疾病。
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引用次数: 0
Heterozygous MEFV Mutation Leading to Renal Failure: A Case Study. 导致肾衰竭的杂合子 MEFV 基因突变:病例研究。
IF 1.4 Q3 PEDIATRICS Pub Date : 2024-08-28 eCollection Date: 2024-01-01 DOI: 10.1177/2333794X241274752
Souhaila El Gazzane, Amine Ichane, Chaimae Nahi, Khadija Mouaddine, Bouchra Chkirate, Aziza Guennoun, Najat Oulahiane, Hassan Ait Ouamar, Lamiaa Rouas

Familial Mediterranean fever (FMF) is an autosomal recessive disorder, particularly common in the Mediterranean area. Mutations in the MEVF gene cause it. AA Amyloidosis is the most severe complication of FMF leading to chronic renal failure. We describe a rare pediatric case of a phenotype I familial Mediterranean fever with V726A heterozygous mutation. The diagnosis was made at chronic kidney disease. We discuss through this case the importance of the early diagnosis of FMF heterozygous children which is not usually evident in some phenotypes. It will surely avoid fatal complications, inappropriate therapeutic approaches and higher healthcare costs.

家族性地中海热(FMF)是一种常染色体隐性遗传疾病,在地中海地区尤为常见。MEVF 基因突变导致该病。AA 淀粉样变性是 FMF 最严重的并发症,可导致慢性肾功能衰竭。我们描述了一例表型为 I 型家族性地中海热并伴有 V726A 杂合突变的罕见儿科病例。诊断结果是慢性肾病。我们通过这个病例讨论了早期诊断 FMF 杂合型儿童的重要性,因为在某些表型中,早期诊断通常并不明显。这必将避免致命的并发症、不恰当的治疗方法和更高的医疗费用。
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引用次数: 0
The Magnitude of Care Burden and Associated Factors in Caregivers of Children with Cancer at the Country's Largest Tertiary Referral Hospital, Ethiopia: A Cross-Sectional Study. 埃塞俄比亚全国最大的三级转诊医院癌症患儿护理人员的护理负担及其相关因素:一项横断面研究。
IF 1.4 Q3 PEDIATRICS Pub Date : 2024-08-28 eCollection Date: 2024-01-01 DOI: 10.1177/2333794X241275258
Gashaw Arega, Abdulkadir M Said, Sosina Workineh, Kedir Hussien, Kassahun Ketema

Objectives. Many caregivers who care for their children with cancer are affected by the care burden due to the chronic nature of the disease. This study aimed to determine the burden of care level and its related factors in the caregivers of children with cancer. Methods. A facility-based, cross-sectional study was conducted at Tikur Anbessa Specialized Hospital. Children diagnosed with cancer and treated at the hospital between July 1 and August 1, 2023, and their caregivers were included. The data were analyzed using SPSS version 25. Descriptive analysis and inferential statistics were used to summarize the data and to determine the association with the dependent variable. Statistical significance was set at P < .05. Results. A total of 208 children with cancer and their caregivers were included in the study. Most children (81, 38.9%) were below 5 years of age, and 80.3% (n = 167) of the patients came from out of Addis Ababa. The most common type of childhood cancer was haemato-lymphoid cancer (n = 117, 56.3%). The mean duration of cancer care after diagnosis was 289.55 days. The median age of caregivers was 35 ± 8.7 years, most of the caregivers were parents of the child (n = 185, 88.9%), married (n = 186, 87%), had a primary level education (n = 66, 31.7), and 87.5% (n = 182) had insufficient income for the cancer treatment cost. The average caring time was 19 to 24 hours for 76.4% (n = 159) of caregivers, and more than one-fourth of caregivers (n = 57, 27.4%) intended to abandon treatment if they couldn't get support to continue the care. The mean care burden in caregivers was 65.76 ± 14 and about, 53.4% (n = 111) and 35.1% (n = 73) of caregivers had moderate and severe care burden. Binary logistic analysis showed the factors associated with an increased care burden were the caregiver's occupational status (P = .034, 95 % CI; AOR (0.064, 0.890)), lack of support from NGOs (P = .037, 95 % CI; AOR (1.053, 5.254), and insufficient monthly income for the treatment (P = .034; 95% CI; AOR (0.064, 0.896)). Conclusion. Most of the caregivers of children with cancer were parents and had insufficient income for the treatment. More than one-fourth had an intention to abandon the cancer treatment. Most caregivers had moderate to severe care burdens.

目标。由于癌症的慢性性质,许多照顾癌症患儿的护理人员都受到护理负担的影响。本研究旨在确定癌症儿童护理者的护理负担水平及其相关因素。研究方法在提库尔安贝萨专科医院开展了一项基于设施的横断面研究。研究对象包括 2023 年 7 月 1 日至 8 月 1 日期间在该医院接受治疗的癌症患儿及其护理人员。数据使用 SPSS 25 版本进行分析。使用描述性分析和推论性统计来总结数据并确定与因变量的关联。统计显著性设定为 P 结果。本研究共纳入了 208 名癌症儿童及其照顾者。大多数儿童(81 人,占 38.9%)年龄在 5 岁以下,80.3% 的患者(n = 167)来自亚的斯亚贝巴以外的地区。最常见的儿童癌症类型是血液淋巴癌(117 人,56.3%)。癌症确诊后的平均治疗时间为 289.55 天。照护者的年龄中位数为 35 ± 8.7 岁,大多数照护者是儿童的父母(185 人,88.9%),已婚(186 人,87%),受过小学教育(66 人,31.7%),87.5%(182 人)的收入不足以支付癌症治疗费用。76.4%的照护者(n = 159)的平均照护时间为 19 至 24 小时,超过四分之一的照护者(n = 57,27.4%)打算在无法获得支持继续照护的情况下放弃治疗。护理人员的平均护理负担为 65.76 ± 14,约有 53.4%(n = 111)和 35.1%(n = 73)的护理人员有中度和重度护理负担。二元逻辑分析表明,护理负担加重的相关因素包括护理者的职业状况(P = .034,95 % CI;AOR (0.064,0.890))、缺乏非政府组织的支持(P = .037,95 % CI;AOR (1.053,5.254))以及每月用于治疗的收入不足(P = .034;95 % CI;AOR (0.064,0.896))。结论大多数癌症患儿的照顾者都是父母,他们的收入不足以支付治疗费用。超过四分之一的照顾者打算放弃癌症治疗。大多数护理人员的护理负担为中度至重度。
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引用次数: 0
Incidental Finding of Arteria Lusoria. 偶然发现卢索里亚动脉
IF 1.4 Q3 PEDIATRICS Pub Date : 2024-08-27 eCollection Date: 2024-01-01 DOI: 10.1177/2333794X241273210
Chaymae Faraj, Sara Essetti, Kaoutar Maslouhi, Nazik Allali, Siham El Haddad, Latifa Chat

The arteria lusoria or retroesophageal right subclavian artery is the most common malformation of the aortic arch. It may be discovered with some symptoms of airway and/or esophageal compression, such as dyspnea or dysphagia, but in most cases it is an asymptomatic pathology. We report a case of a 3 months old patient diagnosed with Down syndrome who was admitted for pulmonary infection with incidental finding of retrooesophageal right subclavian artery.

锁骨动脉或食道后右锁骨下动脉是主动脉弓最常见的畸形。发现时可能伴有呼吸困难或吞咽困难等气道和/或食道受压症状,但大多数情况下是无症状病变。我们报告了一例 3 个月大的唐氏综合征患者,该患者因肺部感染入院,偶然发现食道后右侧锁骨下动脉。
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引用次数: 0
Risk Factors Associated With Drug-Related Side Effects in Children: A Scoping Review. 与儿童药物副作用相关的风险因素:范围界定综述。
IF 1.4 Q3 PEDIATRICS Pub Date : 2024-08-27 eCollection Date: 2024-01-01 DOI: 10.1177/2333794X241273171
Esmaeel Toni, Haleh Ayatollahi, Reza Abbaszadeh, Alireza Fotuhi Siahpirani

Objective. Children's vulnerability to drug-related side effects has been highlighted in several studies. However, there is no consensus on the risk factors associated with these side effects. This study aimed to investigate risk factors associated with drug-related side effects in children. Methods. This scoping review was conducted across multiple databases. The search strategy was created with a focus on drug-related side effects, as they are more predictable based on the pre-determined risk factors. Data were collected, and reported narratively. Results. The demographic, health, hospital, and drug-related risk factors may cause drug-related side effects in children. Among them, low age, sex, polypharmacy, length of hospitalization, and medications used for comorbidities may increase the risk. Conclusion. While most of the risk factors might be similar in adults and children, their impact might be different in these 2 groups. Therefore, future studies should identify more details about the impact of the risk factors in children.

目的。多项研究都强调了儿童容易受到药物副作用的影响。然而,对于与这些副作用相关的风险因素还没有达成共识。本研究旨在调查与儿童药物相关副作用有关的风险因素。研究方法本研究在多个数据库中进行了范围界定。搜索策略主要针对与药物相关的副作用,因为根据预先确定的风险因素,这些副作用更容易预测。收集数据并进行叙述性报告。结果人口、健康、医院和药物相关风险因素可能会导致儿童出现药物相关副作用。其中,低龄、性别、使用多种药物、住院时间和合并症用药可能会增加风险。结论虽然大多数风险因素在成人和儿童中可能相似,但它们对这两个群体的影响可能不同。因此,今后的研究应更详细地确定风险因素对儿童的影响。
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引用次数: 0
A Rare Case of Infantile Myofibromatosis With Intra Cranial Involvement. 颅内受累的婴儿肌纤维瘤病罕见病例
IF 1.4 Q3 PEDIATRICS Pub Date : 2024-08-15 eCollection Date: 2024-01-01 DOI: 10.1177/2333794X241266564
Fatima Zahrae El Mansoury, Zakia El Yousfi, Ayman El Farouki, Siham El Haddad, Nazik Allali, Latifa Chat

Infantile myofibromatosis is a proliferative disorder occurring during infancy and early childhood, marked by the development of nodular or diffuse lesions consisting of various mesenchymal elements. Intracranial involvement is infrequently reported. Here, we present the case of a 3-year-old girl exhibiting a rare manifestation of IM with intracranial parenchymal involvement, displaying a histological pattern documented in existing literature on patients with infantile myofibromatosis. Subsequent MRI follow-up revealed no signs of recurrence.

婴幼儿肌纤维瘤病是一种发生在婴幼儿时期的增生性疾病,其特征是由各种间质成分组成的结节性或弥漫性病变。颅内受累的报道并不多见。在此,我们介绍了一例罕见的颅内实质受累的 3 岁女孩的病例,她的组织学模式在现有的婴儿肌纤维瘤病患者文献中已有记载。随后的核磁共振成像随访显示没有复发迹象。
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引用次数: 0
期刊
Global Pediatric Health
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