Pub Date : 2023-05-24DOI: 10.15406/mojbm.2023.08.00186
José Maria Pereira de Godoy, Laura Souza de Lima, Lenina Mariana de Morais Castellari, Guilherme Gerloff Antunes, Gustavo Josimar Rossini, Henrique Jose Pereira de Godoy, Henrique Amorim Santos, Fernando Reis Neto
The objective of the present study is to report the technical success of the endovascular procedure in the treatment of pseudoaneurysm of the dorsal pancreatic artery. A 60-year-old white male patient came to the emergency room, complaining of the appearance of an ulcerated wound in the distal third of the left lower limb for 20 days. Alcoholic, smoker and previous diagnosis of chronic pancreatitis. On physical examination, upon admission, the abdomen was normotensive, painless on palpation and without masses or visceromegaly. During the investigation of this ulcer and 12 hours after admission, the patient developed diffuse abdominal pain and distension, more intense in the upper abdomen and associated with peritonitis. A computed tomography scan of the upper abdomen and pelvis was performed, which showed a pseudoaneurysm of the dorsal artery of the pancreas with frank extravasation of contrast into the abdominal cavity, in addition to a moderate amount of free blood around the liver. He underwent endovascular embolization treatment, in which he was selectively catheterized splenic artery and dorsal pancreas with therapeutic success.
{"title":"Endovascular treatment of ruptured dorsal pancreatic artery pseudoaneurysm: case report","authors":"José Maria Pereira de Godoy, Laura Souza de Lima, Lenina Mariana de Morais Castellari, Guilherme Gerloff Antunes, Gustavo Josimar Rossini, Henrique Jose Pereira de Godoy, Henrique Amorim Santos, Fernando Reis Neto","doi":"10.15406/mojbm.2023.08.00186","DOIUrl":"https://doi.org/10.15406/mojbm.2023.08.00186","url":null,"abstract":"The objective of the present study is to report the technical success of the endovascular procedure in the treatment of pseudoaneurysm of the dorsal pancreatic artery. A 60-year-old white male patient came to the emergency room, complaining of the appearance of an ulcerated wound in the distal third of the left lower limb for 20 days. Alcoholic, smoker and previous diagnosis of chronic pancreatitis. On physical examination, upon admission, the abdomen was normotensive, painless on palpation and without masses or visceromegaly. During the investigation of this ulcer and 12 hours after admission, the patient developed diffuse abdominal pain and distension, more intense in the upper abdomen and associated with peritonitis. A computed tomography scan of the upper abdomen and pelvis was performed, which showed a pseudoaneurysm of the dorsal artery of the pancreas with frank extravasation of contrast into the abdominal cavity, in addition to a moderate amount of free blood around the liver. He underwent endovascular embolization treatment, in which he was selectively catheterized splenic artery and dorsal pancreas with therapeutic success.","PeriodicalId":127077,"journal":{"name":"MOJ Biology and Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132626284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-18DOI: 10.15406/mojbm.2022.07.00169
Irene Kührer, Stefan Benz, Milica Maksimovic, Béla Teleky
Chemoradio therapy followed by total mesorectal excision is the standard of care for rectal cancer. Although locoregional recurrence and survival have improved, distant recurrence has not. Adjuvant chemotherapy might prevent distant metastases, however, its use for patients with rectal cancer treated with preoperative radiochemotherapy and surgery is largely debated. Available data do not support its routine use in these settings, unlike in colon cancer where adjuvant therapy role is well established. According to ESMO Guidelines, adjuvant chemotherapy after preoperative radiochemo therapy with postoperative histology stage III and high-risk stage II can be considered (level of evidence is lower than in colon cancer). These consensus recommendations have been developed based on the review of current evidence and expert opinions, and are expected to assist in selecting subgroups of patients that could benefit from adjuvant chemotherapy after neoadjuvant radio chemotherapy and TME surgery and choosing chemotherapeutic agent in different post-operative scenarios.
{"title":"Consensus Recommendation (from the 11th Conference of the European Federation for Colorectal Cancer): Adjuvant Chemotherapy after Neoadjuvant Chemoradiotherapy for Rectal Cancer and TME Surgery","authors":"Irene Kührer, Stefan Benz, Milica Maksimovic, Béla Teleky","doi":"10.15406/mojbm.2022.07.00169","DOIUrl":"https://doi.org/10.15406/mojbm.2022.07.00169","url":null,"abstract":"Chemoradio therapy followed by total mesorectal excision is the standard of care for rectal cancer. Although locoregional recurrence and survival have improved, distant recurrence has not. Adjuvant chemotherapy might prevent distant metastases, however, its use for patients with rectal cancer treated with preoperative radiochemotherapy and surgery is largely debated. Available data do not support its routine use in these settings, unlike in colon cancer where adjuvant therapy role is well established. According to ESMO Guidelines, adjuvant chemotherapy after preoperative radiochemo therapy with postoperative histology stage III and high-risk stage II can be considered (level of evidence is lower than in colon cancer). These consensus recommendations have been developed based on the review of current evidence and expert opinions, and are expected to assist in selecting subgroups of patients that could benefit from adjuvant chemotherapy after neoadjuvant radio chemotherapy and TME surgery and choosing chemotherapeutic agent in different post-operative scenarios.","PeriodicalId":127077,"journal":{"name":"MOJ Biology and Medicine","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127124673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-20DOI: 10.15406/mojbm.2023.08.00185
J. Ouedraogo, Lassina Gadi Timbiné, B. Traoré, Abdoul Karim Sangaré, E. Sogodogo, K. Haukka, B. Kouriba, Amadou Hamadoun Babana
In Mali, coli and Salmonella infections are one of the most common bacterial diseases in outpatients. Treatment of these diseases has become challenging due to the emergence of pathogens with increasing resistance to available antimicrobial agents. The aim of this study is to determine the prevalence and evaluate the antibiotic resistance profile of the most frequently isolated strains of these bacteria involved in bacterial infections in Bamako, Mali. In this study, 400 samples of human, animal and environmental origin were obtained in the study area. The isolated bacteria were identified by biochemical tests. Disk diffusion method was applied to determine the antibiotic sensitivity of bacterial agents. Our results showed that, only 321 enterobacteria were isolated from the 958 samples analyzed. The most isolated pathogenic bacteria was E. coli with frequency rate of 20.77%. The others enterobacteria were Klebsiella sp. (6.05%), and Salmonella sp. (3.86%). All pathogenic bacteria isolated in this study, were highly resistant to Amoxicillin, Ticarcillin (100% for Klebsiella sp., isolated from all samples), and sensitive to Imipenem, Cefoxitine and Nitrofurantoine. According to the present survey, apart from Salmonella isolated from human and environmental samples, all the pathogenic bacteria isolated from human, animal and environmental sources showed multiple antibiotic resistance with a MAR index as high as 0.7 for E. coli from human source. This high level of multiresistance indicates that these human, animal and environment at Bamako could constitute a “high risk” source of antibiotic contamination.
{"title":"Multirésistance to antibiotics of pathogens isolated from human, animal and environment in the District of Bamako, Mali","authors":"J. Ouedraogo, Lassina Gadi Timbiné, B. Traoré, Abdoul Karim Sangaré, E. Sogodogo, K. Haukka, B. Kouriba, Amadou Hamadoun Babana","doi":"10.15406/mojbm.2023.08.00185","DOIUrl":"https://doi.org/10.15406/mojbm.2023.08.00185","url":null,"abstract":"In Mali, coli and Salmonella infections are one of the most common bacterial diseases in outpatients. Treatment of these diseases has become challenging due to the emergence of pathogens with increasing resistance to available antimicrobial agents. The aim of this study is to determine the prevalence and evaluate the antibiotic resistance profile of the most frequently isolated strains of these bacteria involved in bacterial infections in Bamako, Mali. In this study, 400 samples of human, animal and environmental origin were obtained in the study area. The isolated bacteria were identified by biochemical tests. Disk diffusion method was applied to determine the antibiotic sensitivity of bacterial agents. Our results showed that, only 321 enterobacteria were isolated from the 958 samples analyzed. The most isolated pathogenic bacteria was E. coli with frequency rate of 20.77%. The others enterobacteria were Klebsiella sp. (6.05%), and Salmonella sp. (3.86%). All pathogenic bacteria isolated in this study, were highly resistant to Amoxicillin, Ticarcillin (100% for Klebsiella sp., isolated from all samples), and sensitive to Imipenem, Cefoxitine and Nitrofurantoine. According to the present survey, apart from Salmonella isolated from human and environmental samples, all the pathogenic bacteria isolated from human, animal and environmental sources showed multiple antibiotic resistance with a MAR index as high as 0.7 for E. coli from human source. This high level of multiresistance indicates that these human, animal and environment at Bamako could constitute a “high risk” source of antibiotic contamination.","PeriodicalId":127077,"journal":{"name":"MOJ Biology and Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133895772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-06DOI: 10.15406/mojbm.2023.08.00176
Marie Claire Cammaerts
Working on ants as models, we examined the side effects of six largely used products, separately published our findings, and here summarize them for the readers’ convenience. The herbicides, the active substance of which is pelargonic acid, must be used only for not cultivated area since they impact the live of the soil fauna. Imodium, the active substance of which is Loperamide, used to stop diarrhea, should be used during short time periods, monitoring the patients as for their food consumption, locomotion, social relationships, cognition and dependence on the drug use. Only small amount of the myorelaxant Epsipram, the active substance of which is Tetrazepam, should be used, monitoring the patients as for their activity, locomotion, social relationships, stress, cognition, memory and dependence on the drug consumption. The antiemetic Motilium, the active substance of which is Domperidone, should be used after having made an adequate clinical examination of the patients, take then care of them monitoring them as for their health since side effects may occur. The dietary supplement Cognizing, the active substance of which is citicoline, should not be used, being inefficient and causing stress, agitation, nervousness and strong dependence on its consumption. The dietary supplement PQQ is efficient and has no adverse effect; it could be used, but at low doses, since, being novel, some not yet observed side effects may occur.
{"title":"Adverse effects, studied on ants, of six products largely used by humans; a mini review","authors":"Marie Claire Cammaerts","doi":"10.15406/mojbm.2023.08.00176","DOIUrl":"https://doi.org/10.15406/mojbm.2023.08.00176","url":null,"abstract":"Working on ants as models, we examined the side effects of six largely used products, separately published our findings, and here summarize them for the readers’ convenience. The herbicides, the active substance of which is pelargonic acid, must be used only for not cultivated area since they impact the live of the soil fauna. Imodium, the active substance of which is Loperamide, used to stop diarrhea, should be used during short time periods, monitoring the patients as for their food consumption, locomotion, social relationships, cognition and dependence on the drug use. Only small amount of the myorelaxant Epsipram, the active substance of which is Tetrazepam, should be used, monitoring the patients as for their activity, locomotion, social relationships, stress, cognition, memory and dependence on the drug consumption. The antiemetic Motilium, the active substance of which is Domperidone, should be used after having made an adequate clinical examination of the patients, take then care of them monitoring them as for their health since side effects may occur. The dietary supplement Cognizing, the active substance of which is citicoline, should not be used, being inefficient and causing stress, agitation, nervousness and strong dependence on its consumption. The dietary supplement PQQ is efficient and has no adverse effect; it could be used, but at low doses, since, being novel, some not yet observed side effects may occur.","PeriodicalId":127077,"journal":{"name":"MOJ Biology and Medicine","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127632904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-29DOI: 10.15406/mojbm.2022.07.00172
Daniel Nobile, Beatriz Camelini Moreno, Amanda Fernandes Vidal da Silva, Vinicius Menin Brandi, José Maria Pereira de Godoy
The aim of the present study is to present a case report of a patient who developed aortic thrombosis with multiple embolizations to kidneys, spleen, superior mesenteric and extremities and a lung tumor mass. A 56-year-old patient, she reports that 45 days ago she had Covid-19 and no need for hospitalization. Now, she presented with abdominal pain and was hospitalized and underwent an angio tomography of the chest, abdomen, aortic thrombosis and emboli in several viscera and extremities. She was medically treated for visceral emboli, but one week later she had an extremity embolism that was treated with an embolectomy. And a lung biopsy revealed neoplasia. Post-Covid 19 aortic thrombus can result in multiple visceral and extremity embolic events, associated with lung cancer, an incidental finding can occur and serves as a warning to these patients.
{"title":"Aortic thrombus with multiple visceral and extremity emboli post Covid-19 with lung cancer","authors":"Daniel Nobile, Beatriz Camelini Moreno, Amanda Fernandes Vidal da Silva, Vinicius Menin Brandi, José Maria Pereira de Godoy","doi":"10.15406/mojbm.2022.07.00172","DOIUrl":"https://doi.org/10.15406/mojbm.2022.07.00172","url":null,"abstract":"The aim of the present study is to present a case report of a patient who developed aortic thrombosis with multiple embolizations to kidneys, spleen, superior mesenteric and extremities and a lung tumor mass. A 56-year-old patient, she reports that 45 days ago she had Covid-19 and no need for hospitalization. Now, she presented with abdominal pain and was hospitalized and underwent an angio tomography of the chest, abdomen, aortic thrombosis and emboli in several viscera and extremities. She was medically treated for visceral emboli, but one week later she had an extremity embolism that was treated with an embolectomy. And a lung biopsy revealed neoplasia. Post-Covid 19 aortic thrombus can result in multiple visceral and extremity embolic events, associated with lung cancer, an incidental finding can occur and serves as a warning to these patients.","PeriodicalId":127077,"journal":{"name":"MOJ Biology and Medicine","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126889936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-23DOI: 10.15406/mojbm.2022.07.00163
S. Ayoade
{"title":"“Complex” kinesiological conundrum-could microzyman machinations/inhibitions explain the relative tardiness of initial infantile human locomotion?","authors":"S. Ayoade","doi":"10.15406/mojbm.2022.07.00163","DOIUrl":"https://doi.org/10.15406/mojbm.2022.07.00163","url":null,"abstract":"","PeriodicalId":127077,"journal":{"name":"MOJ Biology and Medicine","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131310280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-16DOI: 10.15406/mojbm.2022.07.00161
Ana Claudia Araújo da Silva, Ana Rosa Bomfim da Silva, Ana Suzane Pereira Martins, Bárbara Hellen da Silva Azevedo, Emília Natália Santana de Queiroz, Eveline Thomaz Moura Santos de Vasconcelos Soares, Fabiana Freire Anastacio, João Victor Lopes Oliveira, José Leonildo Fernandes de Queiroz, Josias Nelson Torres de Amorim, Joycilaine Beatriz Barros de Lima, Juliana de Pontes Nobre, Juliany Narieza de Carvalho Medeiros, Kaique Warley Nascimento Arrais, Larissa Helena da Silva, Magável Raulinho de Sousa, Mariana Pequeno de Melo, Maurício Caxias de Souza, Nayara Ferreira da Costa, Nara Franklin Santos Martins, Nayra Cristina da Silva, Pamella de Castro Duarte Pordeus, Paula Andréa Rebouças Leite, Thamyris Meygam Gomes Cardoso, Vanessa Silva de Castro Monte
Objective: Describe critical health care for the elderly against COVID-19 in a multidisciplinary approach. Method: This is a qualitative study, with an exploratory documentary and detailed descriptive approach, with a bibliometric emphasis. Where several studies will be gathered for the characterization of each element present in their results. Results and discussion: Several studies were analyzed and discussed about the topics related to this study, they are: critical health care, health of the elderly, Covid-19 and multi disciplinary care. Scientific articles of national and international origin contributed effectively to the discussion of these results. Conclusion: This study achieved its objective, as it described critical health care for the elderly against COVID-19 in a multi disciplinary approach, it contributed satisfactorily to the entire academic community world wide, enabling the creation of new studies on this topic.
{"title":"Critical healthcare for the elderly against COVID-19 : a multidisciplinary approach","authors":"Ana Claudia Araújo da Silva, Ana Rosa Bomfim da Silva, Ana Suzane Pereira Martins, Bárbara Hellen da Silva Azevedo, Emília Natália Santana de Queiroz, Eveline Thomaz Moura Santos de Vasconcelos Soares, Fabiana Freire Anastacio, João Victor Lopes Oliveira, José Leonildo Fernandes de Queiroz, Josias Nelson Torres de Amorim, Joycilaine Beatriz Barros de Lima, Juliana de Pontes Nobre, Juliany Narieza de Carvalho Medeiros, Kaique Warley Nascimento Arrais, Larissa Helena da Silva, Magável Raulinho de Sousa, Mariana Pequeno de Melo, Maurício Caxias de Souza, Nayara Ferreira da Costa, Nara Franklin Santos Martins, Nayra Cristina da Silva, Pamella de Castro Duarte Pordeus, Paula Andréa Rebouças Leite, Thamyris Meygam Gomes Cardoso, Vanessa Silva de Castro Monte","doi":"10.15406/mojbm.2022.07.00161","DOIUrl":"https://doi.org/10.15406/mojbm.2022.07.00161","url":null,"abstract":"Objective: Describe critical health care for the elderly against COVID-19 in a multidisciplinary approach. Method: This is a qualitative study, with an exploratory documentary and detailed descriptive approach, with a bibliometric emphasis. Where several studies will be gathered for the characterization of each element present in their results. Results and discussion: Several studies were analyzed and discussed about the topics related to this study, they are: critical health care, health of the elderly, Covid-19 and multi disciplinary care. Scientific articles of national and international origin contributed effectively to the discussion of these results. Conclusion: This study achieved its objective, as it described critical health care for the elderly against COVID-19 in a multi disciplinary approach, it contributed satisfactorily to the entire academic community world wide, enabling the creation of new studies on this topic.","PeriodicalId":127077,"journal":{"name":"MOJ Biology and Medicine","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121763311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-04DOI: 10.15406/mojbm.2021.06.00156
M. Cammaerts
Using ants as models, we studied until now the side effects of 47 products used by humans and, over these studies we published five summaries of our main findings. After that, we studied the side effects of six other drugs used by humans, and we here summarize these lastly obtained results. These six other drugs were dextromethorphan, amitriptylin, escitalopram, fluvoxamine, iverectin, and indapamide. For each of them, we found side effects similar to those reported for humans, but we also observed side effects not yet mentioned for humans. They concerned among others the locomotion, the activity, the sensory perception, the social relationships and the learning. Practitioners and pharmacists should take cognizance of our works for more adequately and safely used the six drugs we examined. Our six works are published and thus available, but they can also be provided by the author(s). All over our studies, ants appeared to be excellent biological models; the experiments could be made easily, rapidly and at lost cost, while providing statistically significant results.
{"title":"Side effects of drugs studied on ant models: a mini review","authors":"M. Cammaerts","doi":"10.15406/mojbm.2021.06.00156","DOIUrl":"https://doi.org/10.15406/mojbm.2021.06.00156","url":null,"abstract":"Using ants as models, we studied until now the side effects of 47 products used by humans and, over these studies we published five summaries of our main findings. After that, we studied the side effects of six other drugs used by humans, and we here summarize these lastly obtained results. These six other drugs were dextromethorphan, amitriptylin, escitalopram, fluvoxamine, iverectin, and indapamide. For each of them, we found side effects similar to those reported for humans, but we also observed side effects not yet mentioned for humans. They concerned among others the locomotion, the activity, the sensory perception, the social relationships and the learning. Practitioners and pharmacists should take cognizance of our works for more adequately and safely used the six drugs we examined. Our six works are published and thus available, but they can also be provided by the author(s). All over our studies, ants appeared to be excellent biological models; the experiments could be made easily, rapidly and at lost cost, while providing statistically significant results.","PeriodicalId":127077,"journal":{"name":"MOJ Biology and Medicine","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129598406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-03DOI: 10.15406/MOJBM.2019.04.00105
M. Tricot, D. Cammaerts
Homeopathic treatments are considered by the vast majority of the scientific community as non-effective, apart from a well-documented placebo effect. Nevertheless, some experimental results raise questions about their efficiency, and numerous practitioners still consider homeopathy as an efficient alternative treatment instead of usual pharmaceutical drugs. Homeopathy is thus nowadays debated among the general public, practitioners and medical schools, and is still used by many patients in search for “natural” treatments. It is therefore relevant to bring information to feed this debate and to investigate the efficiency and safety of homeopathic drugs. We examined on ants, used as biological models, the effects of a homeopathic drug, Ignatia amara, advocated to ease symptoms of stress. We tested the effects of thus drug on ant’s ethological and physiological traits (1) under normal condition, then (2) under a stressing situation. We found that (1) this drug was not without adverse effects but slightly impacted some ants’ traits; (2) this drug could reduce the adverse effects caused by the stressing situation. It nearly fully restored the ants’ locomotion, orientation ability, audacity, tactile perception, brood caring, social relationship, escaping behavior, cognition, and slightly the memory. No adaptation and no habituation to the effects of Ignatia amara occurred, and no dependence on its consumption developed. The causes and mechanisms of these effects remain unknown to us, but our results support the hypothesis that, in some given cases, for some specific health problems, and using adequate product(s) and dose(s), a homeopathic treatment based on Ignata amara extracts could help patients to recover from stress symptoms.
{"title":"Challenging the safety and efficiency of homeopathy: Ignatia amara as an example, ants as models","authors":"M. Tricot, D. Cammaerts","doi":"10.15406/MOJBM.2019.04.00105","DOIUrl":"https://doi.org/10.15406/MOJBM.2019.04.00105","url":null,"abstract":"Homeopathic treatments are considered by the vast majority of the scientific community as non-effective, apart from a well-documented placebo effect. Nevertheless, some experimental results raise questions about their efficiency, and numerous practitioners still consider homeopathy as an efficient alternative treatment instead of usual pharmaceutical drugs. Homeopathy is thus nowadays debated among the general public, practitioners and medical schools, and is still used by many patients in search for “natural” treatments. It is therefore relevant to bring information to feed this debate and to investigate the efficiency and safety of homeopathic drugs. We examined on ants, used as biological models, the effects of a homeopathic drug, Ignatia amara, advocated to ease symptoms of stress. We tested the effects of thus drug on ant’s ethological and physiological traits (1) under normal condition, then (2) under a stressing situation. We found that (1) this drug was not without adverse effects but slightly impacted some ants’ traits; (2) this drug could reduce the adverse effects caused by the stressing situation. It nearly fully restored the ants’ locomotion, orientation ability, audacity, tactile perception, brood caring, social relationship, escaping behavior, cognition, and slightly the memory. No adaptation and no habituation to the effects of Ignatia amara occurred, and no dependence on its consumption developed. The causes and mechanisms of these effects remain unknown to us, but our results support the hypothesis that, in some given cases, for some specific health problems, and using adequate product(s) and dose(s), a homeopathic treatment based on Ignata amara extracts could help patients to recover from stress symptoms.","PeriodicalId":127077,"journal":{"name":"MOJ Biology and Medicine","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127739837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-31DOI: 10.15406/MOJBM.2018.03.00083
V. Mendez
{"title":"What is life? revisited","authors":"V. Mendez","doi":"10.15406/MOJBM.2018.03.00083","DOIUrl":"https://doi.org/10.15406/MOJBM.2018.03.00083","url":null,"abstract":"","PeriodicalId":127077,"journal":{"name":"MOJ Biology and Medicine","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132137343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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