Pub Date : 2016-11-10DOI: 10.4172/2090-5025.1000098
O. Fatemeh, Hossein Me
The present research is an applied and documental review of the literature through meta-analysis. The statistical population was selected from the field of entrepreneurial performance in small and medium sized enterprises during 2003 to 2013 in which the internal/external effective factors for small/medium incorporates were quantitatively investigated. The findings of frequency distribution Table indicated that only (4) percent of the conducted studies focused on external factors while (96) percent of which were conducted in the internal factors domain. In addition, most of the studies were devoted to the two issues of human resources and research and development which were (26) percent. Moreover, there was no research related to the incorporate size and the status of consultative researchoriented unions and incorporates.
{"title":"Identifying the Components of Small and Medium Sized Enterprises(SMEs) During the Years of 2003 to 2013 (The Conducted Studies in Iranthrough the Method of Content Analysis)","authors":"O. Fatemeh, Hossein Me","doi":"10.4172/2090-5025.1000098","DOIUrl":"https://doi.org/10.4172/2090-5025.1000098","url":null,"abstract":"The present research is an applied and documental review of the literature through meta-analysis. The statistical population was selected from the field of entrepreneurial performance in small and medium sized enterprises during 2003 to 2013 in which the internal/external effective factors for small/medium incorporates were quantitatively investigated. The findings of frequency distribution Table indicated that only (4) percent of the conducted studies focused on external factors while (96) percent of which were conducted in the internal factors domain. In addition, most of the studies were devoted to the two issues of human resources and research and development which were (26) percent. Moreover, there was no research related to the incorporate size and the status of consultative researchoriented unions and incorporates.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115308383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-27DOI: 10.4172/2090-5025.1000097
Ijaz Ul M, David S, Ruediger H
The surgical saws were developed from 3% Y-TZP and 12% Ce-ZrO2 powders. The specimens were isostatic pressed and sintered conventionally. The saw-teeth were machined by CNC machine using diamond tool. The investigation includes the raise in temperature in bone tissue during cutting process with respect to increase in cutting speed and pressure. Thermal damage of bone tissue would be harmful in case of recovery. The rise in temperature during cutting of bone by ceramic saw was compared with stainless steel saw. The significantly lower temperature during bone cutting, excellent corrosion resistance after sterilization, hardness, wear and abrasive resistance properties show the advantages of 3Y-TZP ceramic saws in orthopedic surgeries.
{"title":"Ceramic Materials: An Alternative for Surgical Saws","authors":"Ijaz Ul M, David S, Ruediger H","doi":"10.4172/2090-5025.1000097","DOIUrl":"https://doi.org/10.4172/2090-5025.1000097","url":null,"abstract":"The surgical saws were developed from 3% Y-TZP and 12% Ce-ZrO2 powders. The specimens were isostatic pressed and sintered conventionally. The saw-teeth were machined by CNC machine using diamond tool. The investigation includes the raise in temperature in bone tissue during cutting process with respect to increase in cutting speed and pressure. Thermal damage of bone tissue would be harmful in case of recovery. The rise in temperature during cutting of bone by ceramic saw was compared with stainless steel saw. The significantly lower temperature during bone cutting, excellent corrosion resistance after sterilization, hardness, wear and abrasive resistance properties show the advantages of 3Y-TZP ceramic saws in orthopedic surgeries.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"88 9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126309508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-21DOI: 10.4172/2090-5025.1000099
H. Dolly, Erson
Myanmars mobile network is closing in on nearly 100% population coverage, and is striving for ever increasing geographical coverage. So much so that even future generations of water buffalo in remote areas will be tracked online as part of the “internet of things”, said Lars Erik Tellmann, CEO of Telenor Myanmar.
缅甸的移动网络正在接近100%的人口覆盖率，并正在努力不断扩大地理覆盖率。Telenor缅甸公司的首席执行官Lars Erik Tellmann说，甚至未来偏远地区的水牛也将作为“物联网”的一部分被在线跟踪。
{"title":"Myanmar Connect 2016: In the Future, Even Water Buffalo Will Be Online","authors":"H. Dolly, Erson","doi":"10.4172/2090-5025.1000099","DOIUrl":"https://doi.org/10.4172/2090-5025.1000099","url":null,"abstract":"Myanmars mobile network is closing in on nearly 100% population coverage, and is striving for ever increasing geographical coverage. So much so that even future generations of water buffalo in remote areas will be tracked online as part of the “internet of things”, said Lars Erik Tellmann, CEO of Telenor Myanmar.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129820027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-07DOI: 10.4172/2090-5025.1000095
Takashi Nakamura, A. Acar, Mark Ng
This paper focused on the action of looking at a mobile phone display as a type of nonverbal behavior/ communication and compared it cross-culturally. The diversity of nonverbal behavior/communication was considered to be caused by the difference between Western and non-Western cultures. The questionnaire was conducted in three countries (the USA, Hong Kong and Japan), and a total of 309 subjects participated. The participants were required to record their opinions for the action according to the situation with ‘co-present’ familiar persons. The analysis declared that the difference between the USA and Japan was more pronounced as the relationship with the ‘co-present’ person was more intimate. The results of the Hong Kong sample were intermediate between those of the other two countries. The diversity was discussed in terms of independent/interdependent self in the perspective of cultural comparison and of mobile phone usage. The analysis revealed that the action as a form of nonverbal behavior/communication has functioned in human relationships and has been deeply embedded into culture in the mobile phone era.
{"title":"Cultural Comparison for the Action of Looking At a Mobile Phone Display Focusing on Independent/Interdependent Self","authors":"Takashi Nakamura, A. Acar, Mark Ng","doi":"10.4172/2090-5025.1000095","DOIUrl":"https://doi.org/10.4172/2090-5025.1000095","url":null,"abstract":"This paper focused on the action of looking at a mobile phone display as a type of nonverbal behavior/ communication and compared it cross-culturally. The diversity of nonverbal behavior/communication was considered to be caused by the difference between Western and non-Western cultures. The questionnaire was conducted in three countries (the USA, Hong Kong and Japan), and a total of 309 subjects participated. The participants were required to record their opinions for the action according to the situation with ‘co-present’ familiar persons. The analysis declared that the difference between the USA and Japan was more pronounced as the relationship with the ‘co-present’ person was more intimate. The results of the Hong Kong sample were intermediate between those of the other two countries. The diversity was discussed in terms of independent/interdependent self in the perspective of cultural comparison and of mobile phone usage. The analysis revealed that the action as a form of nonverbal behavior/communication has functioned in human relationships and has been deeply embedded into culture in the mobile phone era.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132315063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-08-24DOI: 10.4172/2090-5025.1000094
S. MaklyginaYu, A. S. Sharova, B. Kundu, V. Balla, R. Steiner, V. Loschenov
Implant-associated infection is a common postoperative complication and remains a serious problem in the surgery. This work describes the development of hydroxyapatite implants with photo-bactericidal properties by the surface coating. The unique coating as crystalline nanoparticles of IR photosensitizers of implant was investigated using infrared spectroscopy. It has been proved that by the interaction of nanoparticles covering implant with the polar solvent, which simulates the interaction of the implant with the biocomponents in vivo (fast proliferating and with immune-competent cells), IR photosensitizers nanoparticles change the spectroscopic properties, becoming fluorescent and phototoxic. Thus, the developed coating based on crystalline IR photosensitizer nanoparticles with studied specific properties should have antibacterial, anti-inflammatory effect by the photodynamic treatment in the near implant area. This research opens the prospect of such technology application in order to provide the local inflammatory and autoimmune reactions prevention in the area of implantation that will improve implant antimicrobial effects and reduce potential long-term cytotoxicity. The results of the study suggest a promising this technology in order to create implants with photo-bactericidal properties.
{"title":"Photo-bactericidal Properties of Hydroxyapatite Implant Surface Coating","authors":"S. MaklyginaYu, A. S. Sharova, B. Kundu, V. Balla, R. Steiner, V. Loschenov","doi":"10.4172/2090-5025.1000094","DOIUrl":"https://doi.org/10.4172/2090-5025.1000094","url":null,"abstract":"Implant-associated infection is a common postoperative complication and remains a serious problem in the surgery. This work describes the development of hydroxyapatite implants with photo-bactericidal properties by the surface coating. The unique coating as crystalline nanoparticles of IR photosensitizers of implant was investigated using infrared spectroscopy. It has been proved that by the interaction of nanoparticles covering implant with the polar solvent, which simulates the interaction of the implant with the biocomponents in vivo (fast proliferating and with immune-competent cells), IR photosensitizers nanoparticles change the spectroscopic properties, becoming fluorescent and phototoxic. Thus, the developed coating based on crystalline IR photosensitizer nanoparticles with studied specific properties should have antibacterial, anti-inflammatory effect by the photodynamic treatment in the near implant area. This research opens the prospect of such technology application in order to provide the local inflammatory and autoimmune reactions prevention in the area of implantation that will improve implant antimicrobial effects and reduce potential long-term cytotoxicity. The results of the study suggest a promising this technology in order to create implants with photo-bactericidal properties.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126492425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-19DOI: 10.4172/2090-5025.1000096
S. Dorozhkin
Dental caries, also known as tooth decay or a cavity, remains a major public health problem in the most communities even though the prevalence of disease has decreased since the introduction of fluorides for dental care. In addition, there is dental erosion, which is a chemical wear of the dental hard tissues without the involvement of bacteria. Besides, there are other dental losses, which may be of a medical (decay or periodontal disease), age (population aging), traumatic (accident) or genetic (disorders) nature. All these cases clearly indicate that biomaterials to fill dental defects appear to be necessary to fulfill customers’ needs regarding the properties and the processing of the products. Bioceramics and glass-ceramics are widely used for these purposes, as dental inlays, onlays, veneers, crowns or bridges. Calcium orthophosphates (CaPO ) belong to bioceramics but they have some specific advantage over other types of bioceramics due to a chemical similarity to the inorganic part of both human and mammalian bones and teeth. Therefore, CaPO (both alone and as constituents of various formulations) are used in dentistry as both dental fillers and implantable scaffolds. This review provides brief knowledge on CaPO and describes in details current state-of-the-art on their applications in dentistry and dentistry-related fields. Among the recognized dental specialties, CaPO are most frequently used in periodontics; however, the majority of the publications on CaPO in dentistry are devoted to unspecified “dental” fields.
{"title":"Calcium orthophosphates (CaPO4) and dentistry","authors":"S. Dorozhkin","doi":"10.4172/2090-5025.1000096","DOIUrl":"https://doi.org/10.4172/2090-5025.1000096","url":null,"abstract":"Dental caries, also known as tooth decay or a cavity, remains a major public health problem in the most communities even though the prevalence of disease has decreased since the introduction of fluorides for dental care. In addition, there is dental erosion, which is a chemical wear of the dental hard tissues without the involvement of bacteria. Besides, there are other dental losses, which may be of a medical (decay or periodontal disease), age (population aging), traumatic (accident) or genetic (disorders) nature. All these cases clearly indicate that biomaterials to fill dental defects appear to be necessary to fulfill customers’ needs regarding the properties and the processing of the products. Bioceramics and glass-ceramics are widely used for these purposes, as dental inlays, onlays, veneers, crowns or bridges. Calcium orthophosphates (CaPO ) belong to bioceramics but they have some specific advantage over other types of bioceramics due to a chemical similarity to the inorganic part of both human and mammalian bones and teeth. Therefore, CaPO (both alone and as constituents of various formulations) are used in dentistry as both dental fillers and implantable scaffolds. This review provides brief knowledge on CaPO and describes in details current state-of-the-art on their applications in dentistry and dentistry-related fields. Among the recognized dental specialties, CaPO are most frequently used in periodontics; however, the majority of the publications on CaPO in dentistry are devoted to unspecified “dental” fields.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126770916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-30DOI: 10.4172/2090-5025.1000093
B. McEntire, R. Lakshminarayanan, Prabhakar Thirugnanasamb, Jacob W. Seitz-Sampson, R. Bock, D. O’Brien
As a relatively new biomaterial, silicon nitride (Si3N4) is currently used as an arthrodesis device in the cervical and thoracolumbar spine, and it is under consideration as a bearing material in total joint arthroplasty. In this paper, the development and validation of the manufacturing processes used in the production of Si3N4 biomedical implants are presented and discussed. Manufacturing was conducted in a facility specifically dedicated for this purpose using processes designed to yield net shape intervertebral spinal spacers by conventional dry-pressing, CNC machining of components in the green state, sintering, and hot isostatic pressing. These manufacturing methods were industrialized using Taguchi fractional factorial experimental designs, followed by implementation of statistical process controls. The roles of various processing parameters including raw materials, pressing, and firing conditions (i.e., time, temperature, and pressure) are elucidated. For these devices, it was demonstrated that acceptable physical, mechanical, and dimensional properties were consistently obtained from carefully designed and statistically controlled processes.
{"title":"Processing and Characterization of Silicon Nitride Bioceramics","authors":"B. McEntire, R. Lakshminarayanan, Prabhakar Thirugnanasamb, Jacob W. Seitz-Sampson, R. Bock, D. O’Brien","doi":"10.4172/2090-5025.1000093","DOIUrl":"https://doi.org/10.4172/2090-5025.1000093","url":null,"abstract":"As a relatively new biomaterial, silicon nitride (Si3N4) is currently used as an arthrodesis device in the cervical and thoracolumbar spine, and it is under consideration as a bearing material in total joint arthroplasty. In this paper, the development and validation of the manufacturing processes used in the production of Si3N4 biomedical implants are presented and discussed. Manufacturing was conducted in a facility specifically dedicated for this purpose using processes designed to yield net shape intervertebral spinal spacers by conventional dry-pressing, CNC machining of components in the green state, sintering, and hot isostatic pressing. These manufacturing methods were industrialized using Taguchi fractional factorial experimental designs, followed by implementation of statistical process controls. The roles of various processing parameters including raw materials, pressing, and firing conditions (i.e., time, temperature, and pressure) are elucidated. For these devices, it was demonstrated that acceptable physical, mechanical, and dimensional properties were consistently obtained from carefully designed and statistically controlled processes.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127372208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-23DOI: 10.4172/2090-5025.1000092
Z. Hogga, N. Merzouk, Hafid Mm
Bioactive glasses with chemical composition 0.1 SiO2-0.2 CaO-0.2 Na2O-0.5 P2O5 have been prepared. The dielectric properties of the samples were measured in the frequency range from 100 Hz to 1 MHz and temperatures range from 100 to 370 K (Tg ≈ 400 K). The obtained data were analysed by the means of dielectric permittivity representation and modelled using the Havriliak–Negami equation. Various relaxation parameters were calculated with accuracy. Furthermore, investigation of the temperature dependence of their relaxation time using the Vogel– Tammam–Fulcher (VTF) model shows the weak interaction between alkali ions constituents and molecular networkformers for temperatures up to the glass transition.
{"title":"Variable-Temperature Measurements of the Dielectric RelaxationSpectroscopy in 0.1 SiO2-0.2 Cao-0.2 Na2O-0.5 P2O5 Bioactive GlassMaterials","authors":"Z. Hogga, N. Merzouk, Hafid Mm","doi":"10.4172/2090-5025.1000092","DOIUrl":"https://doi.org/10.4172/2090-5025.1000092","url":null,"abstract":"Bioactive glasses with chemical composition 0.1 SiO2-0.2 CaO-0.2 Na2O-0.5 P2O5 have been prepared. The dielectric properties of the samples were measured in the frequency range from 100 Hz to 1 MHz and temperatures range from 100 to 370 K (Tg ≈ 400 K). The obtained data were analysed by the means of dielectric permittivity representation and modelled using the Havriliak–Negami equation. Various relaxation parameters were calculated with accuracy. Furthermore, investigation of the temperature dependence of their relaxation time using the Vogel– Tammam–Fulcher (VTF) model shows the weak interaction between alkali ions constituents and molecular networkformers for temperatures up to the glass transition.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"153 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123598490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-02-08DOI: 10.4172/2090-5025.1000090
Himanshu T, S. Sp, Sampath Ka, Prerna M, Ashish J
The aim of the present investigation was to evaluate the role of TiO2+ZrO2 in the system of 45S5 bioactive glass for improving the bioactivity as well as other physical and mechanical properties of 45S5 bioactive glass. The partial substitution of 1,2,3 and 4 mol% of mixed TiO2+ZrO2 (3:2) for SiO2 in 45S5 bioactive glass system was done by melting route at 1400°Cin a globar rod furnace in air. A comparative study on structural and mechanical properties, as well as bioactivity of the glasses, was reported. The glass properties were determined by XRD, FTIR spectrometry, SEM and the bioactivity of the glass samples were evaluated by in vitro test in simulated body fluid (SBF). Density and compressive strength of glass samples were measured. Results indicate that with the partial substitution of TiO2+ZrO2 for SiO2 in 45S5 bioactive glass system, the mechanical properties of the glasses were found to increase significantly. The glass samples exhibited higher density and compressive strength as compared to their corresponding 45S5 bioactive glass. The in vitro studies of glass samples in SBF had shown that the pH of the solution increased with increasing the time period for immersion during the initial stage of the reaction. This indicated the bioactivity of the samples had increased with increasing duration. On later stages, the decrease in pH of the solution with time had shown that the bioactivity of the samples had decreased.
{"title":"Studies on Preparation and Characterization of 45S5 Bioactive Glass Doped with (TiO2 + ZrO2) as Bioactive Ceramic Material","authors":"Himanshu T, S. Sp, Sampath Ka, Prerna M, Ashish J","doi":"10.4172/2090-5025.1000090","DOIUrl":"https://doi.org/10.4172/2090-5025.1000090","url":null,"abstract":"The aim of the present investigation was to evaluate the role of TiO2+ZrO2 in the system of 45S5 bioactive glass for improving the bioactivity as well as other physical and mechanical properties of 45S5 bioactive glass. The partial substitution of 1,2,3 and 4 mol% of mixed TiO2+ZrO2 (3:2) for SiO2 in 45S5 bioactive glass system was done by melting route at 1400°Cin a globar rod furnace in air. A comparative study on structural and mechanical properties, as well as bioactivity of the glasses, was reported. The glass properties were determined by XRD, FTIR spectrometry, SEM and the bioactivity of the glass samples were evaluated by in vitro test in simulated body fluid (SBF). Density and compressive strength of glass samples were measured. Results indicate that with the partial substitution of TiO2+ZrO2 for SiO2 in 45S5 bioactive glass system, the mechanical properties of the glasses were found to increase significantly. The glass samples exhibited higher density and compressive strength as compared to their corresponding 45S5 bioactive glass. The in vitro studies of glass samples in SBF had shown that the pH of the solution increased with increasing the time period for immersion during the initial stage of the reaction. This indicated the bioactivity of the samples had increased with increasing duration. On later stages, the decrease in pH of the solution with time had shown that the bioactivity of the samples had decreased.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129484829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-02-04DOI: 10.4172/2090-5025.1000091
Sampath Ka, T. Himanshu, B. Kevin, S. Sp
Magnetic induction hyperthermia is emerging for cancer treatment with bioceramic materials rather radiotherapy and chemotherapy. Copper substituted cobalt ferrites as Co1-xCuxFe2O4 (where x=0.2, 0.4, 0.6, 0.8) ware prepared through self-propagating high-temperature synthesis (SHS) and the effect of copper on the structural, magnetic and biological properties was investigated. XRD revealed the formation of solid solution and the magnetic measurements showed the formation of soft ferrites as compared to CoFe2O4. The bioactive composite was prepared by incorporating the ferrite having optimum magnetic properties with bioactive glass and the constituent phases in the sintered composite were analyzed by X-ray diffraction (XRD). The bioactive composite comprised of Na2Ca2Si3O9 phase in solid solution. In vitro bioactivity of the composite was investigated in simulated body fluid (SBF) under physiological conditions. The precipitated hydroxy carbonated apatite (HCA) layer was confirmed by Fourier Transform Infra-Red spectrometer (FTIR), scanning electron microscopy (SEM) and XRD techniques. Cell viability and cytotoxicity against osteoblast MG63cell lines exhibit that the composite is cytocompatible.
{"title":"Structural, Magnetic and In Vitro Bioactivity of Co-Cu Ferrite and BioglassComposite for Hyperthermia in Bone Tissue Engineering","authors":"Sampath Ka, T. Himanshu, B. Kevin, S. Sp","doi":"10.4172/2090-5025.1000091","DOIUrl":"https://doi.org/10.4172/2090-5025.1000091","url":null,"abstract":"Magnetic induction hyperthermia is emerging for cancer treatment with bioceramic materials rather radiotherapy and chemotherapy. Copper substituted cobalt ferrites as Co1-xCuxFe2O4 (where x=0.2, 0.4, 0.6, 0.8) ware prepared through self-propagating high-temperature synthesis (SHS) and the effect of copper on the structural, magnetic and biological properties was investigated. XRD revealed the formation of solid solution and the magnetic measurements showed the formation of soft ferrites as compared to CoFe2O4. The bioactive composite was prepared by incorporating the ferrite having optimum magnetic properties with bioactive glass and the constituent phases in the sintered composite were analyzed by X-ray diffraction (XRD). The bioactive composite comprised of Na2Ca2Si3O9 phase in solid solution. In vitro bioactivity of the composite was investigated in simulated body fluid (SBF) under physiological conditions. The precipitated hydroxy carbonated apatite (HCA) layer was confirmed by Fourier Transform Infra-Red spectrometer (FTIR), scanning electron microscopy (SEM) and XRD techniques. Cell viability and cytotoxicity against osteoblast MG63cell lines exhibit that the composite is cytocompatible.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125635200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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