This is the case of a 46-year-old woman who first presented to gynaecology clinic aged 26 with severe dysmenorrhoea. She has medical history of left renal agenesis and a previous left oophorectomy. Over the course of 20 years she was extensively imaged with ultrasound (US), magnetic resonance imaging (MRI) and computerised tomography (CT) with the diagnosis of a right unicornuate uterus with an obstructed left rudimentary horn only made recently following 11 scans. There are many factors in this case that confused the picture and made diagnosis more challenging including an incomplete history, language barrier, possibility of a pelvic kidney and changes in imaging of an obstructed horn.
{"title":"Case Report of a 20-Year Diagnostic Delay; Difficulty in Diagnosing a Uterine Anomaly","authors":"Jessica Garner, M. Woolley, D. Bell, F. Evans","doi":"10.33425/2639-9342.1161","DOIUrl":"https://doi.org/10.33425/2639-9342.1161","url":null,"abstract":"This is the case of a 46-year-old woman who first presented to gynaecology clinic aged 26 with severe dysmenorrhoea. She has medical history of left renal agenesis and a previous left oophorectomy. Over the course of 20 years she was extensively imaged with ultrasound (US), magnetic resonance imaging (MRI) and computerised tomography (CT) with the diagnosis of a right unicornuate uterus with an obstructed left rudimentary horn only made recently following 11 scans. There are many factors in this case that confused the picture and made diagnosis more challenging including an incomplete history, language barrier, possibility of a pelvic kidney and changes in imaging of an obstructed horn.","PeriodicalId":12828,"journal":{"name":"Gynecology & reproductive health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84279633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Although pregnancy and breast-feeding involve adequate calcium mobilization, it is not recognized if these affect the acquisition of a healthy peak bone mass (PBM) and, hence, postmenopausal osteoporosis (PMOP). The aim of this review was to evaluate osteoporosis in postmenopausal women and its association with breastfeeding. Searches were conducted in PubMed Central and Scopus to find relevant literature and studies. Searching terms were “osteoporosis” AND “breastfeeding. There was no time restriction applied. Language was restricted to English, German and Greek. Results from different studies evaluating the association of breastfeeding and osteoporosis in women are contradictory. While some show a beneficial and protective effect of breastfeeding, others show a detrimental impact and some studies show no association at all. Postmenopausal osteoporosis (PMOP) has long been a pervasive public health concern and the prevention, assessment and management of postmenopausal osteoporosis is particularly important. Thus, more research is needed on the association of breastfeeding and osteoporosis to be able to give accurate recommendations to women.
{"title":"Breastfeeding and Postmenopausal Osteoporosis","authors":"Sarantaki A","doi":"10.33425/2639-9342.1162","DOIUrl":"https://doi.org/10.33425/2639-9342.1162","url":null,"abstract":"Although pregnancy and breast-feeding involve adequate calcium mobilization, it is not recognized if these affect the acquisition of a healthy peak bone mass (PBM) and, hence, postmenopausal osteoporosis (PMOP). The aim of this review was to evaluate osteoporosis in postmenopausal women and its association with breastfeeding. Searches were conducted in PubMed Central and Scopus to find relevant literature and studies. Searching terms were “osteoporosis” AND “breastfeeding. There was no time restriction applied. Language was restricted to English, German and Greek. Results from different studies evaluating the association of breastfeeding and osteoporosis in women are contradictory. While some show a beneficial and protective effect of breastfeeding, others show a detrimental impact and some studies show no association at all. Postmenopausal osteoporosis (PMOP) has long been a pervasive public health concern and the prevention, assessment and management of postmenopausal osteoporosis is particularly important. Thus, more research is needed on the association of breastfeeding and osteoporosis to be able to give accurate recommendations to women.","PeriodicalId":12828,"journal":{"name":"Gynecology & reproductive health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90078102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: It was known that polycystic ovary syndrome (PCOS) patients have high AMH levels. The aim of this study is to show whether low AMH levels are associated with better clinical pregnancy rates in patients with PCOS. Methods: This retrospective study was performed on 443 patients with PCOS referred to BAU MedicalparkGoztepe Hospital IVF Clinic from January 2015 to October 2020. Participants ranged in age from 18 to 40, had their first two IVF trials, had performed frozen-thawed embryo transfer (FET) cycle at day 5. The diagnosis of PCOS was made using the Rotterdam criteria. Data related to patients' AMH were compared with each other, and based on the value, participants were divided into two groups: the first group was AMH≥7 (N = 49); The second group was AMH <7 (N = 394). Results: The pregnancy test was positive for 288 (65%) participants. Of these participants, 214 had livebirth, 71 had miscarriages, and 3 had stillbirths. There was no significant difference in age and BMI between the two groups. There were no significant differences between the two groups in the number of stimulation days, the total number of oocytes, and MII oocytes. The numbers of frozen embryos were higher in the AMH≥7 group (p = 0.005). The positive pregnancy results were significantly higher in the AMH<7 group than in the AMH≥ 7 group (P= 0.02). There was no significant difference in live birth, stillbirth, and miscarriage rates between the two groups. Conclusion: Low levels of circulating AMH are associated with better clinical pregnancy rates in patients with PCOS.
{"title":"Low Antimullerian Hormone Levels Improve Fertility Outcome in Patients with Polycystic Ovary Syndrome","authors":"A. Yurci, N. Gungor","doi":"10.33425/2639-9342.1156","DOIUrl":"https://doi.org/10.33425/2639-9342.1156","url":null,"abstract":"Background: It was known that polycystic ovary syndrome (PCOS) patients have high AMH levels. The aim of this study is to show whether low AMH levels are associated with better clinical pregnancy rates in patients with PCOS. Methods: This retrospective study was performed on 443 patients with PCOS referred to BAU MedicalparkGoztepe Hospital IVF Clinic from January 2015 to October 2020. Participants ranged in age from 18 to 40, had their first two IVF trials, had performed frozen-thawed embryo transfer (FET) cycle at day 5. The diagnosis of PCOS was made using the Rotterdam criteria. Data related to patients' AMH were compared with each other, and based on the value, participants were divided into two groups: the first group was AMH≥7 (N = 49); The second group was AMH <7 (N = 394). Results: The pregnancy test was positive for 288 (65%) participants. Of these participants, 214 had livebirth, 71 had miscarriages, and 3 had stillbirths. There was no significant difference in age and BMI between the two groups. There were no significant differences between the two groups in the number of stimulation days, the total number of oocytes, and MII oocytes. The numbers of frozen embryos were higher in the AMH≥7 group (p = 0.005). The positive pregnancy results were significantly higher in the AMH<7 group than in the AMH≥ 7 group (P= 0.02). There was no significant difference in live birth, stillbirth, and miscarriage rates between the two groups. Conclusion: Low levels of circulating AMH are associated with better clinical pregnancy rates in patients with PCOS.","PeriodicalId":12828,"journal":{"name":"Gynecology & reproductive health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78461920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mustafa Zakaria, Aya Al-ibraheemi, M. Ennaji, W. Senhaji, A. Natiq, Romaissa Boutiche, M. Mbaye, M. Zarqaoui, M. Hassan, Hayder A. Mossa, N. Louanjli
Sperm DNA fragmentation is common in infertile male. Besides, sperm DNA integrity is essential for fertilization and healthy offspring development. Numerous genetic and environmental elements are associated with impacting sperm DNA integrity negatively. Such as lifestyle, ageing, industrial toxins, and infection. The mechanisms behind SDF are many, but apoptosis and reactive oxygen species are considered the main SDF mechanisms. The management of male infertility has led to the desire for more advanced SDF diagnostic tools to diagnose sperm DNA. Numerous sperm DNA damage assays such as terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labelling (TUNEL) assay and in situ nick translation (ISNT) are available to enhance SDF diagnosing and ultimately to better SDF management. Clinical SDF can lead to a low pregnancy rate, defects in embryo development and impaired offspring health. Moreover, SDF can impact the effectiveness of assisted reproductive technology through transfer genetics impartment to the embryo b in vitro fertilization or intracytoplasmic sperm injection. SDF can be mange through lifestyle changing, treating existing infection in the male reproductive tract and reactive oxygen species.
{"title":"Clinical Guidelines for Sperm DNA Fragmentation (SDF) is Associated with Male Infertility from Reactive Oxygen Species (ROS)","authors":"Mustafa Zakaria, Aya Al-ibraheemi, M. Ennaji, W. Senhaji, A. Natiq, Romaissa Boutiche, M. Mbaye, M. Zarqaoui, M. Hassan, Hayder A. Mossa, N. Louanjli","doi":"10.33425/2639-9342.1159","DOIUrl":"https://doi.org/10.33425/2639-9342.1159","url":null,"abstract":"Sperm DNA fragmentation is common in infertile male. Besides, sperm DNA integrity is essential for fertilization and healthy offspring development. Numerous genetic and environmental elements are associated with impacting sperm DNA integrity negatively. Such as lifestyle, ageing, industrial toxins, and infection. The mechanisms behind SDF are many, but apoptosis and reactive oxygen species are considered the main SDF mechanisms. The management of male infertility has led to the desire for more advanced SDF diagnostic tools to diagnose sperm DNA. Numerous sperm DNA damage assays such as terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labelling (TUNEL) assay and in situ nick translation (ISNT) are available to enhance SDF diagnosing and ultimately to better SDF management. Clinical SDF can lead to a low pregnancy rate, defects in embryo development and impaired offspring health. Moreover, SDF can impact the effectiveness of assisted reproductive technology through transfer genetics impartment to the embryo b in vitro fertilization or intracytoplasmic sperm injection. SDF can be mange through lifestyle changing, treating existing infection in the male reproductive tract and reactive oxygen species.","PeriodicalId":12828,"journal":{"name":"Gynecology & reproductive health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83981362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valentim Priscila Margarete Araujo Beserra, Bernardes Jamile Martins, V. F. Resende, A. De, P. Silva, C. Antônio
Background: Female genital malformations are a consequence of abnormalities in the differentiation of the Müllerian ducts at different phases during embryogenesis, resulting in a variety of clinical outcomes. HerlynWerner-Wunderlich (HWW) syndrome is a rare congenital anomaly of the female urogenital tract involving the paramesonephric ducts (Müllerian ducts). The syndrome is characterized by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis. Case: This paper describes the case of a 14-year-old girl presenting with pelvic pain, abdominal swelling and the triad that is characteristic of HWW syndrome. Diagnosis was based on the patient’s clinical history and imaging findings. The patient underwent surgery involving complete drainage of a hematocolpos retained in the obstructed vaginal cavity and resection of the vaginal septum. The procedure was successful in providing symptomatic relief. Twelve months following surgery, the patient’s menstrual cycles were regular, with no dysmenorrhea. Discussion: Greater understanding of this syndrome is crucial in ensuring that diagnosis is reached at an early stage, thus preventing complications such as retrograde menstruation, endometriosis, infections, adhesions, infertility, and acute or chronic pelvic pain.
{"title":"Gynatresia in Herlyn-Werner-Wunderlich Syndrome: A Case Report","authors":"Valentim Priscila Margarete Araujo Beserra, Bernardes Jamile Martins, V. F. Resende, A. De, P. Silva, C. Antônio","doi":"10.33425/2639-9342.1160","DOIUrl":"https://doi.org/10.33425/2639-9342.1160","url":null,"abstract":"Background: Female genital malformations are a consequence of abnormalities in the differentiation of the Müllerian ducts at different phases during embryogenesis, resulting in a variety of clinical outcomes. HerlynWerner-Wunderlich (HWW) syndrome is a rare congenital anomaly of the female urogenital tract involving the paramesonephric ducts (Müllerian ducts). The syndrome is characterized by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis. Case: This paper describes the case of a 14-year-old girl presenting with pelvic pain, abdominal swelling and the triad that is characteristic of HWW syndrome. Diagnosis was based on the patient’s clinical history and imaging findings. The patient underwent surgery involving complete drainage of a hematocolpos retained in the obstructed vaginal cavity and resection of the vaginal septum. The procedure was successful in providing symptomatic relief. Twelve months following surgery, the patient’s menstrual cycles were regular, with no dysmenorrhea. Discussion: Greater understanding of this syndrome is crucial in ensuring that diagnosis is reached at an early stage, thus preventing complications such as retrograde menstruation, endometriosis, infections, adhesions, infertility, and acute or chronic pelvic pain.","PeriodicalId":12828,"journal":{"name":"Gynecology & reproductive health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79069183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Bah, Glenn Jing Yan Lye, S. A. Gunaravi, S. Toh, Vigneswari Vijayan, Grace Soon En Ting, Su Ming Tham, N. Dominic, R. Jeganathan, Valliammai Jayanthi Thirunavuk Arasoo
Objective: To evaluate the association between maternal obesity and the risk of selected foetal abnormalities (neural tube defects and orofacial clefts) in Malaysia. Materials and Methods: We conducted a single-centre retrospective observational study on all women who delivered at Hospital Sultanah Aminah Johor Bahru, Malaysia from 1st January 2017 to 31st December 2018. The presence of neural tube defects (NTD) and orofacial clefts (OC) were identified from medical records, including all live births, stillbirths and terminations of pregnancy. All deliveries during the study period were reviewed to collect data on maternal weight, height and demographics. We performed multiple logistic regression to estimate factors contributing to selected anomalies. Results: A total of 28,228 pregnancies were included. There were 57 NTD-affected pregnancies and 34 OCaffected pregnancies identified during the two-year study period. There was no statistically significant association found between maternal obesity and the occurrence of NTDs or OCs. Pre-gestational diabetes had a significant association with NTD-affected pregnancies (aOR 3.454, 95% CI [1.017, 11.725], p=0.091). The highest incidence rate of NTDs was among Malaysian Indians (2.540 per 1,000 deliveries). Malaysian Chinese and Malaysians of other ethnicities were found to have a significantly higher risk of having OC-affected pregnancies with aOR of 2.371 (95% CI [1.035-5.428], p=0.024) and 4.910 (95% CI [1.454-16.579], p=0.024) respectively. Conclusion: Our study showed no significant association between maternal obesity and selected foetal abnormalities (NTD and OC), and that pre-gestational diabetes is a significant risk factor for NTD in Malaysia.
目的:评估马来西亚产妇肥胖与胎儿畸形(神经管缺陷和口面裂)风险之间的关系。材料和方法:我们对2017年1月1日至2018年12月31日在马来西亚新山苏丹阿米娜医院分娩的所有妇女进行了一项单中心回顾性观察研究。从医疗记录中确定神经管缺陷(NTD)和口面裂(OC)的存在，包括所有活产，死产和妊娠终止。研究人员对研究期间的所有分娩进行了审查，以收集产妇体重、身高和人口统计数据。我们进行了多重逻辑回归来估计导致所选异常的因素。结果:共纳入28228例妊娠。在为期两年的研究期间，有57例ntd影响妊娠和34例ocd影响妊娠。未发现产妇肥胖与ntd或OCs的发生有统计学意义的关联。妊娠前糖尿病与ntd影响妊娠有显著相关性(aOR 3.454, 95% CI [1.017, 11.725]， p=0.091)。被忽视热带病发病率最高的是马来西亚裔印度人(每1000例分娩中有2540例)。马来西亚华人和其他种族的马来西亚人患oc影响妊娠的风险明显更高，aOR分别为2.371 (95% CI [1.035-5.428]， p=0.024)和4.910 (95% CI [1.454-16.579]， p=0.024)。结论:我们的研究显示，产妇肥胖与选择性胎儿异常(NTD和OC)之间没有显著关联，妊娠前糖尿病是马来西亚NTD的重要危险因素。
{"title":"Maternal Obesity and the Risk of Selected Foetal Abnormalities (Neural Tube Defects and Orofacial Clefts) In Malaysia: A Retrospective Observational Study","authors":"Y. Bah, Glenn Jing Yan Lye, S. A. Gunaravi, S. Toh, Vigneswari Vijayan, Grace Soon En Ting, Su Ming Tham, N. Dominic, R. Jeganathan, Valliammai Jayanthi Thirunavuk Arasoo","doi":"10.33425/2639-9342.1157","DOIUrl":"https://doi.org/10.33425/2639-9342.1157","url":null,"abstract":"Objective: To evaluate the association between maternal obesity and the risk of selected foetal abnormalities (neural tube defects and orofacial clefts) in Malaysia. Materials and Methods: We conducted a single-centre retrospective observational study on all women who delivered at Hospital Sultanah Aminah Johor Bahru, Malaysia from 1st January 2017 to 31st December 2018. The presence of neural tube defects (NTD) and orofacial clefts (OC) were identified from medical records, including all live births, stillbirths and terminations of pregnancy. All deliveries during the study period were reviewed to collect data on maternal weight, height and demographics. We performed multiple logistic regression to estimate factors contributing to selected anomalies. Results: A total of 28,228 pregnancies were included. There were 57 NTD-affected pregnancies and 34 OCaffected pregnancies identified during the two-year study period. There was no statistically significant association found between maternal obesity and the occurrence of NTDs or OCs. Pre-gestational diabetes had a significant association with NTD-affected pregnancies (aOR 3.454, 95% CI [1.017, 11.725], p=0.091). The highest incidence rate of NTDs was among Malaysian Indians (2.540 per 1,000 deliveries). Malaysian Chinese and Malaysians of other ethnicities were found to have a significantly higher risk of having OC-affected pregnancies with aOR of 2.371 (95% CI [1.035-5.428], p=0.024) and 4.910 (95% CI [1.454-16.579], p=0.024) respectively. Conclusion: Our study showed no significant association between maternal obesity and selected foetal abnormalities (NTD and OC), and that pre-gestational diabetes is a significant risk factor for NTD in Malaysia.","PeriodicalId":12828,"journal":{"name":"Gynecology & reproductive health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76367377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Clomiphene citrate (CC) is first choice as an ovulation-stimulating drug in polycystic ovarian syndrome. Anovulation problems could occur in some patients presenting with CC resistance. In PCOS patients, very high levels of AMH were observed. The role of anti-Müllerian hormone (AMH) in the prediction of ovarian response to CC in women with the polycystic ovarian syndrome (PCOS) is investigated in this study. Objective: To assess the predictive value of Anti Mullerian hormone (AMH) in Clomiphene citrate response in patients with polycystic ovary syndrome. Methods: This cross-sectional study was conducted at Tanta University Hospitals, Egypt. The study included 120 anovulatory PCOS women who underwent ovarian stimulation with clomiphene citrate. Day 3 measurement of AMH concentrations was done. Results: Cycles with poor response had significantly (p<0.0001) higher basal serum AMH concentration compared to that of cycles with normal response. AMH area under receiver operating characteristic curve (ROCAUC) 0.88; (p<0.001) and 0.81; (p<0.007) respectively. Using a cut-off level of 6.3 ng/ml, the good response rate was significantly (p < .001) higher in cycles with lower AMH (<6.3 ng/ml) compared to that in those with AMH (> = 6.3) ng/ml. Conclusion: AMH levels could predict the ovarian response to clomiphene citrate in PCO women.
{"title":"Maternal Obesity and the Risk of Selected Foetal Abnormalities (Neural Tube Defects and Orofacial Clefts) In Malaysia: A Retrospective Observational Study","authors":"A. Dawood, H. Lotfy, M. Omar","doi":"10.33425/2639-9342.1158","DOIUrl":"https://doi.org/10.33425/2639-9342.1158","url":null,"abstract":"Background: Clomiphene citrate (CC) is first choice as an ovulation-stimulating drug in polycystic ovarian syndrome. Anovulation problems could occur in some patients presenting with CC resistance. In PCOS patients, very high levels of AMH were observed. The role of anti-Müllerian hormone (AMH) in the prediction of ovarian response to CC in women with the polycystic ovarian syndrome (PCOS) is investigated in this study. Objective: To assess the predictive value of Anti Mullerian hormone (AMH) in Clomiphene citrate response in patients with polycystic ovary syndrome. Methods: This cross-sectional study was conducted at Tanta University Hospitals, Egypt. The study included 120 anovulatory PCOS women who underwent ovarian stimulation with clomiphene citrate. Day 3 measurement of AMH concentrations was done. Results: Cycles with poor response had significantly (p<0.0001) higher basal serum AMH concentration compared to that of cycles with normal response. AMH area under receiver operating characteristic curve (ROCAUC) 0.88; (p<0.001) and 0.81; (p<0.007) respectively. Using a cut-off level of 6.3 ng/ml, the good response rate was significantly (p < .001) higher in cycles with lower AMH (<6.3 ng/ml) compared to that in those with AMH (> = 6.3) ng/ml. Conclusion: AMH levels could predict the ovarian response to clomiphene citrate in PCO women.","PeriodicalId":12828,"journal":{"name":"Gynecology & reproductive health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77851697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study was planned to determine the perinatal outcomes of the newborns of term pregnant women who were diagnosed with GDM and decided to have cesarean delivery. Materials and Methods: Thirty-five pregnant patients diagnosed with GDM were included in the study. The control group consisted of 35 patients who did not have any pregnancy-related disease and were decided to deliver with elective cesarean section. All participants were screened with a 50-g GCT at 24-28 weeks of gestation. Pregnant women with meeting the following laboratory criteria were accepted as GDM. If the serum glucose level was greater than 140 mg/dL on the 50-g GCT, a 100-g OGTT was applied. Diagnosis of GDM was confirmed if 2 of the blood glucose test results were above the following levels: fasting serum glucose ≥ 92 mg/dL and/or 1-hour glycemia ≥ 180 mg/dL, and/or 2-hour glycemia ≥ 153 mg/dL. Perinatal outcome between GDM subjects and control group was compared. All participants in GDM and control groups underwent cesarean deivery. Primary outcome measures included gestational birthweight, gestational age at delivery, stillbirth and neonatal death, minor and major birth defects. Results: While neonatal hypoglycemia was detected in 4 cases in the GDM group, it was found in one case in the control group. No stilbirth was detected in either the GDM group or the control group. While neonatal death was detected in one case in the GDM group, no neonatal death was observed in the control group. While mild preeclampsia was detected in one case in the GDM group, it was not found in the control group. Birth weeks and birth weights of the cases in both groups were recorded similarly. While 8 babies of 2500 grams or less were born in GDM cases, all of the cases in the control group were over 2500 grams. While prematurity was detected in two babies in the GDM group, no prematurity was reported in the control group. Neonatal intensive care needs were seen in three babies in the GDM group, and there were no infants in need of intensive care in the control group. Conclusions: There is a slight increase in low birth weight, prematurity and intensive care unit needs of babies born to mothers with GDM.
{"title":"Perinatal Outcome in Newborns of Women with Gestational Diabetes Mellitus","authors":"B. Baysal, O. Oner","doi":"10.33425/2639-9342.1155","DOIUrl":"https://doi.org/10.33425/2639-9342.1155","url":null,"abstract":"Objective: This study was planned to determine the perinatal outcomes of the newborns of term pregnant women who were diagnosed with GDM and decided to have cesarean delivery. Materials and Methods: Thirty-five pregnant patients diagnosed with GDM were included in the study. The control group consisted of 35 patients who did not have any pregnancy-related disease and were decided to deliver with elective cesarean section. All participants were screened with a 50-g GCT at 24-28 weeks of gestation. Pregnant women with meeting the following laboratory criteria were accepted as GDM. If the serum glucose level was greater than 140 mg/dL on the 50-g GCT, a 100-g OGTT was applied. Diagnosis of GDM was confirmed if 2 of the blood glucose test results were above the following levels: fasting serum glucose ≥ 92 mg/dL and/or 1-hour glycemia ≥ 180 mg/dL, and/or 2-hour glycemia ≥ 153 mg/dL. Perinatal outcome between GDM subjects and control group was compared. All participants in GDM and control groups underwent cesarean deivery. Primary outcome measures included gestational birthweight, gestational age at delivery, stillbirth and neonatal death, minor and major birth defects. Results: While neonatal hypoglycemia was detected in 4 cases in the GDM group, it was found in one case in the control group. No stilbirth was detected in either the GDM group or the control group. While neonatal death was detected in one case in the GDM group, no neonatal death was observed in the control group. While mild preeclampsia was detected in one case in the GDM group, it was not found in the control group. Birth weeks and birth weights of the cases in both groups were recorded similarly. While 8 babies of 2500 grams or less were born in GDM cases, all of the cases in the control group were over 2500 grams. While prematurity was detected in two babies in the GDM group, no prematurity was reported in the control group. Neonatal intensive care needs were seen in three babies in the GDM group, and there were no infants in need of intensive care in the control group. Conclusions: There is a slight increase in low birth weight, prematurity and intensive care unit needs of babies born to mothers with GDM.","PeriodicalId":12828,"journal":{"name":"Gynecology & reproductive health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87715644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To assess the level of awareness and knowledge of HPV infection and vaccination among 648 Teens from secondary schools and colleges in four metro cities of Port Harcourt Nigeria. Materials and methods: This cross-sectional study was conducted by from 1st March to 31st August, 2018. Girls of 13–19 years, with an average of 16 years are targeted. A written questionnaire with two parts has been applied. A preliminary written questionnaire included questions of HPV infection and vaccination awareness. Results: The study participants are poorly aware about HPV infection and vaccination but are intensely willing to know about it. 98% (n-632) are not aware of HPV infection, while, 98% (n–636) is not aware of the vaccination. Conclusions: This study brings out the unawareness about HPV infection and vaccination in urban adolescent in four metro cities in Port Harcourt Nigeria. Adolescent understanding and being aware of the HPV virus is needed to have successful vaccination programs in Nigeria.
{"title":"Awareness of HPV Infection and Vaccination Among Teens in Urban School, Nigeria","authors":"Faith C. Diorgu, Kelechim N Diorgu","doi":"10.33425/2639-9342.1151","DOIUrl":"https://doi.org/10.33425/2639-9342.1151","url":null,"abstract":"To assess the level of awareness and knowledge of HPV infection and vaccination among 648 Teens from secondary schools and colleges in four metro cities of Port Harcourt Nigeria. Materials and methods: This cross-sectional study was conducted by from 1st March to 31st August, 2018. Girls of 13–19 years, with an average of 16 years are targeted. A written questionnaire with two parts has been applied. A preliminary written questionnaire included questions of HPV infection and vaccination awareness. Results: The study participants are poorly aware about HPV infection and vaccination but are intensely willing to know about it. 98% (n-632) are not aware of HPV infection, while, 98% (n–636) is not aware of the vaccination. Conclusions: This study brings out the unawareness about HPV infection and vaccination in urban adolescent in four metro cities in Port Harcourt Nigeria. Adolescent understanding and being aware of the HPV virus is needed to have successful vaccination programs in Nigeria.","PeriodicalId":12828,"journal":{"name":"Gynecology & reproductive health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82102332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Hamza, Zwawa Alia, Elmahaishi Wael M, Elmahaishi Ms
Hematometrocolpos usually caused by obstruction of lower genital tract, somewhere in the vagina such as Imperforated hymen. In our case there is no obstruction in the vagina, but started at the cervix in a form of membrane. This membrane extended in the vagina forming intavaginal cyst which filled with blood and by time gave the complete picture of hematometrocolpos. This case aged 53 years old, para7 and presenting to our clinic complaining of urinary retention burning of micturition and secondary amenorrhea for 9 months.
{"title":"Secondary Amenorrhea Due to Unusual Cause (Hematometrocolpos)","authors":"E. Hamza, Zwawa Alia, Elmahaishi Wael M, Elmahaishi Ms","doi":"10.33425/2639-9342.1154","DOIUrl":"https://doi.org/10.33425/2639-9342.1154","url":null,"abstract":"Hematometrocolpos usually caused by obstruction of lower genital tract, somewhere in the vagina such as Imperforated hymen. In our case there is no obstruction in the vagina, but started at the cervix in a form of membrane. This membrane extended in the vagina forming intavaginal cyst which filled with blood and by time gave the complete picture of hematometrocolpos. This case aged 53 years old, para7 and presenting to our clinic complaining of urinary retention burning of micturition and secondary amenorrhea for 9 months.","PeriodicalId":12828,"journal":{"name":"Gynecology & reproductive health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82013748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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