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A high fiber diet or supplementation with Lactococcus lactis subspecies cremoris to pregnant mice confers protection against intestinal injury in adult offspring 妊娠小鼠摄入高纤维饮食或补充 Cremoris 乳球菌亚种可保护成年后代免受肠道损伤
IF 12.2 1区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1080/19490976.2024.2337317
Maria E. Barbian, Joshua A. Owens, Crystal R. Naudin, Patricia Denning, Ravi M. Patel, Rheinallt M. Jones
The diet during pregnancy, or antenatal diet, influences the offspring’s intestinal health. We previously showed that antenatal butyrate supplementation reduces injury in adult murine offspring wit...
孕期饮食或产前饮食会影响后代的肠道健康。我们以前曾研究发现,产前补充丁酸盐可减少成年小鼠后代肠道损伤的发生。
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引用次数: 0
Multi-strain probiotics during pregnancy in women with obesity influence infant gut microbiome development: results from a randomized, double-blind placebo-controlled study 肥胖妇女孕期服用多菌株益生菌会影响婴儿肠道微生物组的发育:一项随机双盲安慰剂对照研究的结果
IF 12.2 1区 医学 Q1 Medicine Pub Date : 2024-04-09 DOI: 10.1080/19490976.2024.2337968
Sofie Ingdam Halkjær, Malene Refslund Danielsen, Victoria E. de Knegt, Lee O’Brien Andersen, Christen Rune Stensvold, Henrik Vedel Nielsen, Hengameh Chloé Mirsepasi-Lauridsen, Karen Angeliki Krogfelt, Dina Cortes, Andreas Munk Petersen
Probiotics have been described to influence host health and prevent the risk of obesity by gut microbiome (GM) modulation. In a randomized double-blinded placebo-controlled feasibility study, we in...
益生菌可通过调节肠道微生物组(GM)影响宿主健康并预防肥胖风险。在一项随机双盲安慰剂对照的可行性研究中,我们在...
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引用次数: 0
New treatment approaches for Clostridioides difficile infections: alternatives to antibiotics and fecal microbiota transplantation 艰难梭菌感染的新治疗方法:抗生素和粪便微生物群移植的替代品
IF 12.2 1区 医学 Q1 Medicine Pub Date : 2024-04-09 DOI: 10.1080/19490976.2024.2337312
Tomaž Bratkovič, Abida Zahirović, Maruša Bizjak, Maja Rupnik, Borut Štrukelj, Aleš Berlec
Clostridioides difficile causes a range of debilitating intestinal symptoms that may be fatal. It is particularly problematic as a hospital-acquired infection, causing significant costs to the heal...
难辨梭状芽孢杆菌会引起一系列令人衰弱的肠道症状,甚至可能致命。作为一种医院获得性感染,它的问题尤为严重,会给医护人员带来巨大的经济损失...
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引用次数: 0
Cognitive behavioral and mindfulness with daily exercise intervention is associated with changes in intestinal microbial taxa and systemic inflammation in patients with Crohn’s disease 认知行为和正念与日常锻炼干预与克罗恩病患者肠道微生物类群和全身炎症的变化有关
IF 12.2 1区 医学 Q1 Medicine Pub Date : 2024-04-09 DOI: 10.1080/19490976.2024.2337269
Ilan K, Motro Y, Nemirovsky A, Schwartz D, Goren G, Sergienko R, Greenberg D, Slonim-Nevo V, Sarid O, Friger M, Regev S, Odes S, Moran-Gilad J, Monsonego A
Crohn’s disease (CD) is a chronic inflammatory bowel disease associated with psychological distress and intestinal microbial changes. Here, we examined whether a 3-month period of Cognitive Behavio...
克罗恩病(CD)是一种慢性炎症性肠病,与心理压力和肠道微生物变化有关。在这里,我们研究了为期 3 个月的认知行为疗法是否对克罗恩病有帮助。
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引用次数: 0
CobB-mediated deacetylation of the chaperone CesA regulates Escherichia coli O157:H7 virulence CobB 介导的伴侣蛋白 CesA 去乙酰化调控大肠杆菌 O157:H7 的毒力
IF 12.2 1区 医学 Q1 Medicine Pub Date : 2024-03-19 DOI: 10.1080/19490976.2024.2331435
Linxing Li, Bin Yang, Jing Wang, Yi Wei, Binbin Xiang, Yutao Liu, Pan Wu, Wanwu Li, Yanling Wang, Xinyu Zhao, Jingliang Qin, Miaomiao Liu, Ruiying Liu, Guozhen Ma, Tian Fu, Min Wang, Bin Liu
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a common food-borne pathogen that can cause acute diseases. Lysine acetylation is a post-translational modification (PTM) that occurs in various...
肠出血性大肠杆菌 (EHEC) O157:H7 是一种常见的食源性病原体,可导致急性疾病。赖氨酸乙酰化是一种翻译后修饰 (PTM),发生在不同的大肠杆菌中...
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引用次数: 0
Long- and short-term effects of fecal microbiota transplantation on antibiotic resistance genes: results from a randomized placebo-controlled trial 粪便微生物群移植对抗生素耐药基因的长期和短期影响:随机安慰剂对照试验的结果
IF 12.2 1区 医学 Q1 Medicine Pub Date : 2024-03-13 DOI: 10.1080/19490976.2024.2327442
Armin Rashidi, Maryam Ebadi, Tauseef Ur Rehman, Heba Elhusseini, David Kazadi, Hossam Halaweish, Mohammad H. Khan, Andrea Hoeschen, Qing Cao, Xianghua Luo, Amanda J. Kabage, Sharon Lopez, Shernan G. Holtan, Daniel J. Weisdorf, Chang Liu, Satoshi Ishii, Alexander Khoruts, Christopher Staley
In small series, third-party fecal microbiota transplantation (FMT) has been successful in decolonizing the gut from clinically relevant antibiotic resistance genes (ARGs). Less is known about the ...
在小范围内,第三方粪便微生物群移植(FMT)成功地清除了肠道中与临床相关的抗生素耐药基因(ARGs)。但人们对这种方法的...
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引用次数: 0
Chemotherapy-induced microbiota exacerbates the toxicity of chemotherapy through the suppression of interleukin-10 from macrophages 化疗诱导的微生物群通过抑制巨噬细胞的白细胞介素-10而加剧化疗的毒性
IF 12.2 1区 医学 Q1 Medicine Pub Date : 2024-02-24 DOI: 10.1080/19490976.2024.2319511
Zhen He, Hongyu Xie, Haoyang Xu, Jinjie Wu, Wanyi Zeng, Qilang He, Christian Jobin, Sanqing Jin, Ping Lan
The gut microbiota has been shown to influence the efficacy and toxicity of chemotherapy, thereby affecting treatment outcomes. Understanding the mechanism by which microbiota affects chemotherapeu...
肠道微生物群已被证明会影响化疗的疗效和毒性,从而影响治疗效果。了解微生物群对化疗的影响机制可以帮助我们更好地了解化疗的疗效。
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引用次数: 0
S-amlodipine induces liver inflammation and dysfunction through the alteration of intestinal microbiome in a rat model 在大鼠模型中,S-氨氯地平通过改变肠道微生物组诱发肝脏炎症和功能障碍
IF 12.2 1区 医学 Q1 Medicine Pub Date : 2024-02-24 DOI: 10.1080/19490976.2024.2316923
Xinxin Liu, Hui Fang, Liuzhu Pan, Peng Zhang, Huai Lin, Huihui Gao, Chaolin Ye, Daqing Mao, Yi Luo
S-amlodipine, a commonly prescribed antihypertensive agent, is widely used in clinical settings to treat hypertension. However, the potential adverse effects of long-term S-amlodipine treatment on ...
S-氨氯地平是一种常用的降压药,被广泛用于临床治疗高血压。然而,长期服用 S-amlodipine 可能会对人体产生不良影响。
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引用次数: 0
The biotherapeutic Clostridium butyricum MIYAIRI 588 strain potentiates enterotropism of Rorγt+Treg and PD-1 blockade efficacy 生物治疗用丁酸梭菌 MIYAIRI 588 菌株可增强 Rorγt+Treg 的肠动力和 PD-1 阻断疗效
IF 12.2 1区 医学 Q1 Medicine Pub Date : 2024-02-22 DOI: 10.1080/19490976.2024.2315631
Thomas Paz Del Socorro, Kentaro Oka, Olivier Boulard, Motomichi Takahashi, Lionel Franz Poulin, Atsushi Hayashi, Mathias Chamaillard
Immune checkpoint inhibitors (ICI) have been positioned as a standard of care for patients with advanced non-small-cell lung carcinomas (NSCLC). A pilot clinical trial has reflected optimistic asso...
免疫检查点抑制剂(ICI)已被定位为晚期非小细胞肺癌(NSCLC)患者的标准治疗方法。一项试点临床试验显示,免疫检查点抑制剂对晚期非小细胞肺癌(NSCLC)患者的疗效令人乐观。
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引用次数: 0
A universe of human gut-derived bacterial prophages: unveiling the hidden viral players in intestinal microecology 人类肠道细菌噬菌体的宇宙:揭示肠道微生态中隐藏的病毒角色
IF 12.2 1区 医学 Q1 Medicine Pub Date : 2024-02-01 DOI: 10.1080/19490976.2024.2309684
Zhangming Pei, Yufei Liu, Yutao Chen, Tong Pan, Xihao Sun, Hongchao Wang, R. Paul Ross, Wenwei Lu, Wei Chen
Prophages, which are an existing form of temperate phages that integrate into host genomes, have been found extensively present in diverse bacterial species. The human gut microbiome, characterized...
噬菌体是一种整合到宿主基因组中的现有温带噬菌体形式,已被发现广泛存在于不同的细菌物种中。人类肠道微生物组的特点是...
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引用次数: 0
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Gut Microbes
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