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2012 International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)最新文献

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Pseudo-random sequences in analysis of polyvinylidene fluoride piezoelectric sensors 聚偏氟乙烯压电传感器分析中的伪随机序列
T. Roinila, Lei Lihui, M. Vilkko, G. Dandan, Xiong Wenming, P. Kallio
The ability to measure the force order of micronewtons with high accuracy is highly important in various applications of micromanipulation. Past studies have indicated that polyvinylidene fluoride (PVDF) piezoelectric sensors are the most promising tools with which to measure such forces. This paper presents fast and nondestructive frequency-domain methods with which to electrically characterize and analyze the properties of PVDF piezoelectric sensors. The maximum-length binary sequence (MLBS) is used as an excitation and the system-characterizing responses are measured through cross-correlation techniques. The results can be used to verify the feasibility of the applied PVDF in terms of resonance frequency, bandwidth, and other characterizing properties, which provides tools for more accurate force measurements. Experimental results are shown from a commercial PVDF polymer film.
高精度测量微牛顿力阶的能力在各种微操作应用中是非常重要的。过去的研究表明,聚偏氟乙烯(PVDF)压电传感器是最有希望测量这种力的工具。本文提出了一种快速、无损的频域方法,用于对PVDF压电传感器进行电学表征和性能分析。采用最大长度二值序列(MLBS)作为激励,通过相互关联技术测量系统表征响应。结果可用于验证所应用PVDF在共振频率、带宽和其他表征特性方面的可行性,为更精确的力测量提供工具。本文给出了一种商用PVDF聚合物薄膜的实验结果。
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引用次数: 2
Microlens array film fabricated by UV roll-to-roll nanoimprinting for enhancing out-coupling efficiency of organic light-emitting devices 利用紫外卷对卷纳米压印技术制备微透镜阵列薄膜,提高有机发光器件的外耦合效率
S. Shen, Fang Zhou, D. Pu, G. Wei, Yun Zhou
Microlens arrays film fabricated by UV roll-to-roll nanoimprinting lithography is introduced on glass substrate to improve the out-coupling efficiency of organic light-emitting devices. The microlenses suppress wave guiding loss in the substrate and a theoretical model, based on Monto-Carlo model, is developed to simulate the enhancement effects. The numerical results show that ellipsoidal-like microlens array can increase the efficiency by a factor of more than 35% and the luminance density distribution along the orthogonal directions can be compressed by 10 degree. Such a microlens array mold is fabricated by a combination of DMD-based laser direct writing lithography and thermal reflow method, followed by electroforming for transferring the surface structure to a nickel plate. The obtained mold is wrapped on a roller for the mass production of microlens array film by UV roll-to-roll nanoimprinting process. OLED attached with such microlens array film with a maximum increase of 35% in efficiency is achieved and directional out-coupling phenomenon can be observed experimentally. Such a directional out-coupling microlens array film can be used to OLED to enhance the luminous intensity efficiency and save power consumption for future lighting and display application.
为了提高有机发光器件的外耦合效率,在玻璃基板上引入了紫外卷对卷纳米压印技术制备的微透镜阵列薄膜。微透镜抑制了基片中的导波损耗,并建立了基于蒙特卡罗模型的理论模型来模拟这种增强效果。数值计算结果表明,椭球微透镜阵列的效率提高了35%以上,且正交方向的光密度分布可压缩10度。采用基于dmd的激光直写光刻和热回流相结合的方法制备微透镜阵列模具,然后电铸将表面结构转移到镍板上。将得到的模具包裹在滚轮上,采用UV卷对卷纳米压印工艺批量生产微透镜阵列薄膜。应用该微透镜阵列薄膜后,OLED的效率最高可提高35%,并在实验中观察到定向外耦合现象。这种定向外耦合微透镜阵列薄膜可用于OLED,提高发光强度效率,节省功耗,用于未来的照明和显示应用。
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引用次数: 2
A new material concept for three-dimensional tactile piezoresistive force sensors 三维触觉压阻力传感器的新材料概念
A. Jordan, S. Buttgenbach
The purpose of this paper is to present a new material concept to develop highly sensitive three-dimensional tactile force sensors. Conventional three-dimensional force sensors are based on silicon with integrated diffused silicon piezoresistors. Micromechanical force sensors using a soft material instead, e. g. SU-8 resist, would be more sensitive for static deflection measurements. As a characteristic factor for the sensitivity, the ratio of the gauge factor k to the Young's modulus E is presented for different sensor types. Beside silicon, especially gold, carbon black particles, and diamond-like carbon is taken into consideration as piezoresistive material. In addition four different SU-8 sensor prototypes are mechanically characterized with regard to their bending stiffness, probing forces at different deflections, and breaking points.
本文的目的是提出一种新的材料概念来开发高灵敏度的三维触觉力传感器。传统的三维力传感器是基于硅和集成扩散硅压敏电阻。使用软材料的微机械力传感器,例如SU-8电阻,将对静态挠度测量更敏感。作为灵敏度的特征因子,给出了不同类型传感器的测量因子k与杨氏模量E的比值。压阻材料除硅外,特别是金、炭黑颗粒和类金刚石碳也被认为是压阻材料。此外,四种不同的SU-8传感器原型根据其弯曲刚度、不同挠度下的探测力和断裂点进行了机械表征。
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引用次数: 1
Fabrication of submicron-sized metal patterns on a flexible polymer substrate by femtosecond laser sintering of metal nanoparticles 用飞秒激光烧结金属纳米颗粒在柔性聚合物衬底上制备亚微米尺寸的金属图案
Y. Son, J. Yeo, C. Ha, Sukjoon Hong, S. Ko, Dong-Yol Yang
The femtosecond laser sintering of metal nanoparticles was studied in order to fabricate submicron-sized metal patterns on flexible polymer substrates for various applications in the electronic and photonic industries. In this process, a mode-locked Ti:sapphire laser beam was tightly focused on silver nanoparticles. To achieve a homogeneous dispersion of the silver nanoparticles, the nanoparticles were prepared using a two-phase reduction method wherein the silver nanoparticles were encapsulated by functional surfactants. The key advantage of the femtosecond laser sintering process is that it reduces the heat-affected zone during sintering, as the femtosecond (10-15s) laser pulse is shorter than the heat diffusion time (picosecond: 10-12s). Therefore, sintering of metal nanoparticles is limited to the laser focal spot and the thermal diffusion effect is suppressed, enabling the realization of submicron-sized metal patterns on flexible polymer substrates. Through this process, metal conductors with submicron-sized features and high conductivity were successfully fabricated. As demonstrated by the obtained results, the femtosecond laser sintering of metal nanoparticles is a novel process that offers direct, low-temperature, ultra-high-resolution results, and which will have numerous further applications in electronics and photonics.
研究了飞秒激光烧结金属纳米颗粒的方法,在柔性聚合物衬底上制备亚微米尺寸的金属图案,用于电子和光子工业的各种应用。在这个过程中,锁模钛蓝宝石激光束紧密聚焦在银纳米颗粒上。为了实现银纳米粒子的均匀分散,采用两相还原法制备了纳米粒子,其中银纳米粒子被功能性表面活性剂包裹。飞秒激光烧结工艺的关键优势在于减少了烧结过程中的热影响区,因为飞秒(10-15s)激光脉冲比热扩散时间(皮秒:10-12s)短。因此,金属纳米颗粒的烧结被限制在激光焦点光斑内,抑制了热扩散效应,使得在柔性聚合物衬底上实现亚微米尺寸的金属图案成为可能。通过该工艺,成功制备了具有亚微米尺寸和高导电性的金属导体。所获得的结果表明,飞秒激光烧结金属纳米颗粒是一种新颖的工艺,可以提供直接、低温、超高分辨率的结果,并将在电子和光子学领域有许多进一步的应用。
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引用次数: 10
Autonomous operating process for zebrafish embryo injection 斑马鱼胚胎注射的自主操作过程
Wang Yiliao, Sun Mingzhu, Zhao Xin, Zhao Baoquan
Embryo injection is a significant technique in molecule biology and drug discovery for zebrafish, one of the most popular model organisms. Traditional zebrafish embyo injection is manually conducted under microscope, requiring challenging coordination of hand, eye and foot and their respective precise control as well as ceaseless labour. An autonomous operating process for zebrafish embryo injection is proposed in this paper. Based on a micromanipulation robot system, the operating process integrates computer vision and micromanipulation robot control to realize batch embryo injection automatically. Successful rate of 93% and survival ratio of 89.5% at operating speed of 6-7 embryos are obtained, verifying the feasibility and effectiveness of the process. Finally, the process is applied to investigate the toxicity of a dye and receives success.
胚胎注射是斑马鱼分子生物学和药物发现的重要技术,斑马鱼是最受欢迎的模式生物之一。传统的斑马鱼胚胎注射是在显微镜下手工进行的,需要手、眼、脚的协调和各自的精确控制,需要不断的劳动。提出了一种用于斑马鱼胚胎注射的自主操作流程。以微操作机器人系统为基础,将计算机视觉与微操作机器人控制相结合,实现胚胎批量自动注射。在6-7个胚胎的运行速度下,成功率为93%,存活率为89.5%,验证了该工艺的可行性和有效性。最后,将该方法应用于染料的毒性研究并获得成功。
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引用次数: 4
Force sensor for cell injection and characterization 用于细胞注射和表征的力传感器
A. Shulev, I. Roussev, K. Kostadinov
This paper presents the basics idea and principles of a force sensor for cell injection and characterization of mechanical properties of cells. It utilizes fluidics, piezo resistive MEMS, and piezo actuated mechanics to provide sub-micronewton sensitivity in vertical injection mode. The prototyping, calibration and investigation of the proposed sensor are also presented in brief. Main advantages and drawbacks are also discussed.
本文介绍了一种用于细胞注射的力传感器的基本思想和原理,以及细胞力学性能的表征。它利用流体、压电电阻MEMS和压电驱动力学,在垂直注入模式下提供亚微牛顿的灵敏度。本文还简要介绍了该传感器的原型设计、标定和研究。并对其主要优点和缺点进行了讨论。
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引用次数: 6
Wide-angle reflective-type color filter in the visible range 广角反射式滤色片在可见光范围内
Yun Zhou, Y. Ye, S. Shen, D. Pu, Linsen Chen
A reflective-type color filter in the visible range is theoretically investigated. It consists of a transparent flexible substrate, a layer of thick metal, and two-dimensional dielectric-metal grating. The filter proposed here has the advangtages of insensitivity to incident-angle and polarization-independence. It is found that the variations of its geometric parameters can tune the selective wavelength to generate different colors. The angular dependence of the reflection spectrum for TM and TE polarized light is simulated and analyzed. The position of the reflection valley and the full-width at half-maximum (FWHM) remain almost unchanged when the incident angle is increased to 30 degree. The useful future of the structure is the low dependence of the reflection spectrum on the incident-angle and the polarizations which can be utilized for reflective display.
从理论上研究了可见光范围内的反射式滤色器。它由透明的柔性衬底、一层厚金属和二维介质金属光栅组成。该滤波器对入射角不敏感,与偏振无关。发现其几何参数的变化可以调节选择波长以产生不同的颜色。模拟分析了TM和TE偏振光反射光谱的角依赖性。当入射角增加到30度时,反射谷的位置和半最大全宽(FWHM)基本保持不变。该结构的有用前景是反射光谱对入射角和偏振的依赖性较低,可用于反射显示。
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引用次数: 0
Recognition of living abnormal cells based on an optical microscope 基于光学显微镜的活异常细胞识别
X. Liang, Hongmei Xu, Yang Liu
A method is presented to monitor and analyze tumor cells' biological process by image processing techniques based on an optical microscope in this paper. Meanwhile, the hybrid operation combination of the micro and nano manipulation plays a crucial role in studying living cells' biological process and the interactions of cells and drugs. In this paper, we propose an improved image segmentation method which can be used for the recognition of living abnormal cells. We segment cell images using a threshold segmentation algorithm, combining an improved boundary breakpoint connection algorithm with an improved hole filling algorithm. The method was tested using images from an inverted light microscope. Experimental results demonstrate that the elapsed time of the whole recognition process is about 10 seconds, and the recognition rate is high.
本文提出了一种基于光学显微镜的图像处理技术监测和分析肿瘤细胞生物学过程的方法。同时,微纳操作的混合操作结合在研究活细胞的生物过程以及细胞与药物的相互作用方面发挥着至关重要的作用。本文提出了一种改进的图像分割方法,可用于活体异常细胞的识别。我们使用阈值分割算法分割细胞图像,结合改进的边界断点连接算法和改进的孔填充算法。使用倒置光学显微镜的图像对该方法进行了测试。实验结果表明,整个识别过程耗时约10秒,识别率较高。
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引用次数: 2
Progress in cancer diagnosis and treatment based on gold nanorods 基于金纳米棒的癌症诊断与治疗进展
Tian-mu Zhang, Changli Li, Lihui Zhao, Yu Ren, G. Mo-ran, Xi-he Zhang, H. Cai
In this paper, the progress in cancer diagnosis and treatment were reviewed which is based on gold nanorods (Au-NRs). Synthesis and properties of Au-NRs were described, more specifically on typical methods of surface modification, surface active agent selection, as well as biological image and cancer treatment which are based on Au-NRs. Also current difficulty and future development were discussed.
本文综述了基于金纳米棒(Au-NRs)的肿瘤诊断和治疗的研究进展。介绍了Au-NRs的合成和性质,重点介绍了基于Au-NRs的典型表面改性方法、表面活性剂的选择以及基于Au-NRs的生物成像和癌症治疗。并对目前存在的困难和今后的发展进行了探讨。
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引用次数: 2
The step towards an ultimate multifunctional tool for nanotechnology 迈向纳米技术终极多功能工具的一步
M. Zadražil, J. Jiruše, B. Lencová, J. Dluhoš, T. Hrncír, M. Rudolf, L. Sedláček, T. Šamořil
The need for a combination of a number of observation and analytical methods in a single instrument minimizes the time consuming moving of the studied sample among several devices for different applications and avoids the navigation to the studied object with features in nanometer dimensions. The high-resolution Schottky FE SEM and Ga FIB that allow imaging in different signals were combined with SPM, which adds complementary surface images in-situ. The system can be equipped with a number of detectors for electrons, secondary ions, cathodoluminescence as well as analytical detectors for X-rays and time-of-flight spectrometer of secondary ions. Electron and ion lithography, electron and ion beam induced deposition, and FIB sputtering and slicing for 3D tomography can be performed. Several application examples illustrate the use of the tool.
需要在一台仪器中结合多种观察和分析方法,最大限度地减少了在不同应用的几个设备之间移动研究样品的时间,并避免了导航到具有纳米尺寸特征的研究对象。可以在不同信号下成像的高分辨率Schottky FE SEM和Ga FIB与SPM相结合,增加了原位互补表面图像。该系统可配备多个电子、二次离子、阴极发光探测器以及x射线分析探测器和二次离子飞行时间光谱仪。可以进行电子和离子光刻,电子和离子束诱导沉积,FIB溅射和三维断层扫描切片。几个应用程序示例说明了该工具的使用。
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引用次数: 1
期刊
2012 International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)
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