Pub Date : 2022-07-31DOI: 10.32771/inajog.v10i3.1597
G. Hermawan, I. Nym. Gde. D. Mahardhika, Jennie D. Sutantio, Dyana S. Velies
Objective: To report a rare case of hydranencephaly that was diagnosed during prenatal period. We also provided further review of differential diagnosis and management performed in Ende District General Hospital, based on appropriate literatures and guidelines available. Methods: Case Report Case: A 27-year old primigravida women was diagnosed with term pregnancy (37 weeks of gestation) and intra-uterine singleton live fetus with hydranencephaly via ultrasonography. In this patient, emergency caesarean section (CS) was performed to prevent complication of cephalo-pelvic disproportion (CPD), involving teamwork between obstetrics and perinatology. A male neonate was born weighing 3000 grams, head circumference of 32 cm, and APGAR score of 2/4/7/8 suggestive of asphyxia and respiratory distress. The newborn was immediately transferred to Neonatal Intensive Care Unit (NICU) for further resuscitative management and observation. The newborn remains in stable condition after resuscitative management was given. Post-natal transcranial sonography (TCS) of the newborn was performed by a pediatrician, and the diagnosis of hydranencephaly was confirmed. The newborn was later referred to facilities with neurosurgery department for further evaluation and intervention. Conclusion: Early prenatal recognition of hydranencephaly and exclusion of similar differential diagnosis, which includes: hydrocephalus, holoproscencephaly, porencephaly and schizencephaly, are fundamental in formulating proper multidisciplinary management with pediatric and neurosurgery department, which may consequently improve the newborn’s life expectancy. Keywords: Hydranencephaly, Differential Diagnosis, Management. Abstrak Tujuan: Melaporkan suatu kasus langka hidranensefali yang kami diagnosa dalam periode prenatal; dan memberikan ulasan lanjut mengenai diagnosis diferensial dan manajemen yang kami kerjakan di Rumah Sakit Umum Ende, berdasarkan literatur dan pedoman ilmiah yang tersedia. Methode: Laporan Kasus Kasus: Seorang perempuan primigravida berusia 27 tahun di diagnosa dengan kehamilan aterm (37 minggu gestasi), janin tunggal hidup intrauterin dengan hidranensefali via ultrasonografi. Pada pasien ini dilakukan Sectio Caesarea (SC) cito untuk mencegah komplikasi dari disproporsi kepala-panggul dengan kerjasama tim kebidanan dan perinatologi. Lahir bayi laki-laki dengan berat badan 3000 gram, lingkar kepala 32 cm, dan skor APGAR 2/4/7/8 dengan kesan asfiksia dan distres pernapasan. Bayi segera dipindahkan ke Neonatal Intensive Care Unit (NICU) untuk penanganan resusitatif lanjut dan observasi. Bayi tetap bertahan dalam kondisi stabil setelah diberikan manajemen resusitatif. Pemeriksaan sonografi transkranial paska natal dilakukan oleh dokter anak, dan diagnosis hidranensefali terkonfirmasi. Bayi kemudian di rujuk ke fasilitas dengan ketersediaan departemen bedah saraf untuk evaluasi dan intervensi lanjut. Kesimpulan: Deteksi dini prenatal hidranen
{"title":"Prenatal Differential Diagnosis and Prospective Management of Hydranencephaly","authors":"G. Hermawan, I. Nym. Gde. D. Mahardhika, Jennie D. Sutantio, Dyana S. Velies","doi":"10.32771/inajog.v10i3.1597","DOIUrl":"https://doi.org/10.32771/inajog.v10i3.1597","url":null,"abstract":"Objective: To report a rare case of hydranencephaly that was diagnosed during prenatal period. We also provided further review of differential diagnosis and management performed in Ende District General Hospital, based on appropriate literatures and guidelines available. \u0000 \u0000Methods: Case Report \u0000 \u0000Case: A 27-year old primigravida women was diagnosed with term pregnancy (37 weeks of gestation) and intra-uterine singleton live fetus with hydranencephaly via ultrasonography. In this patient, emergency caesarean section (CS) was performed to prevent complication of cephalo-pelvic disproportion (CPD), involving teamwork between obstetrics and perinatology. A male neonate was born weighing 3000 grams, head circumference of 32 cm, and APGAR score of 2/4/7/8 suggestive of asphyxia and respiratory distress. The newborn was immediately transferred to Neonatal Intensive Care Unit (NICU) for further resuscitative management and observation. The newborn remains in stable condition after resuscitative management was given. Post-natal transcranial sonography (TCS) of the newborn was performed by a pediatrician, and the diagnosis of hydranencephaly was confirmed. The newborn was later referred to facilities with neurosurgery department for further evaluation and intervention. \u0000 \u0000Conclusion: Early prenatal recognition of hydranencephaly and exclusion of similar differential diagnosis, which includes: hydrocephalus, holoproscencephaly, porencephaly and schizencephaly, are fundamental in formulating proper multidisciplinary management with pediatric and neurosurgery department, which may consequently improve the newborn’s life expectancy. \u0000 \u0000Keywords: Hydranencephaly, Differential Diagnosis, Management. \u0000 \u0000Abstrak \u0000 \u0000Tujuan: Melaporkan suatu kasus langka hidranensefali yang kami diagnosa dalam periode prenatal; dan memberikan ulasan lanjut mengenai diagnosis diferensial dan manajemen yang kami kerjakan di Rumah Sakit Umum Ende, berdasarkan literatur dan pedoman ilmiah yang tersedia. \u0000 \u0000Methode: Laporan Kasus \u0000 \u0000Kasus: Seorang perempuan primigravida berusia 27 tahun di diagnosa dengan kehamilan aterm (37 minggu gestasi), janin tunggal hidup intrauterin dengan hidranensefali via ultrasonografi. Pada pasien ini dilakukan Sectio Caesarea (SC) cito untuk mencegah komplikasi dari disproporsi kepala-panggul dengan kerjasama tim kebidanan dan perinatologi. Lahir bayi laki-laki dengan berat badan 3000 gram, lingkar kepala 32 cm, dan skor APGAR 2/4/7/8 dengan kesan asfiksia dan distres pernapasan. Bayi segera dipindahkan ke Neonatal Intensive Care Unit (NICU) untuk penanganan resusitatif lanjut dan observasi. Bayi tetap bertahan dalam kondisi stabil setelah diberikan manajemen resusitatif. Pemeriksaan sonografi transkranial paska natal dilakukan oleh dokter anak, dan diagnosis hidranensefali terkonfirmasi. Bayi kemudian di rujuk ke fasilitas dengan ketersediaan departemen bedah saraf untuk evaluasi dan intervensi lanjut. \u0000 \u0000Kesimpulan: Deteksi dini prenatal hidranen","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46834471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.32771/inajog.v10i3.1801
S. Sulistyawati
Pathogenesis of preeclampsia as the consequences of the interaction failure between trophoblast and womb, mainly in the 1 st trimester leads to a stress response in the placenta. This may cause poor growth and development of the villous tree, deteriorating transfer of oxygen and nutrients to the fetus. 1 In the simultaneous way huge number of placental debris as the result of necrotic-apoptotic process is released into maternal circulation. 1,2 That of phenomenon related to syncytiotrophoblastic stress is triggering endothelial dysregulation and extreme in fl ammation process, and so do the clinical respond related, such as: hypertension, proteinuria, edema, convulsion, cerebral edema, acute renal failure, acute liver dysfunction, thrombocytopenia (which are as the maternal complications) and fetal growth restriction, preterm delivery, still birth (which are as the fetal complications). 3 Fetal growth restriction (FGR) which could be develop solely or as one entity of early-onset preeclampsia is mostly caused by the poor attitude of extravillous trophoblast cells (EVT) in doing its work on maternal spiral artery remodeling process. 4 As we can see clear from the large data of scienti fi c evidence, the only signi fi cant modality to prevent FGR until recent is by giving low-dose aspirin before 16 weeks of gestational age in selected pregnancies with high resistance index of uterine artery shown by doppler velocimetry ultrasound. 5 Beyond that, only timely delivery after series of close monitoring that will give better perinatal outcome. 6 This will often end with preterm delivery, which increases the percentage of preterm birth in general. 6 In the placenta accreta spectrum (PAS) is a condition where the trophoblast invasion is too aggressive. The development of PAS is a complex multifactorial process related to the combination of decidual-myometrial (as the results of previous c-section or other gynecological surgery), absence the basal plate
{"title":"Abnormal Trophoblast Invasion: The Culprit of The Major Obstetrics Problems","authors":"S. Sulistyawati","doi":"10.32771/inajog.v10i3.1801","DOIUrl":"https://doi.org/10.32771/inajog.v10i3.1801","url":null,"abstract":"Pathogenesis of preeclampsia as the consequences of the interaction failure between trophoblast and womb, mainly in the 1 st trimester leads to a stress response in the placenta. This may cause poor growth and development of the villous tree, deteriorating transfer of oxygen and nutrients to the fetus. 1 In the simultaneous way huge number of placental debris as the result of necrotic-apoptotic process is released into maternal circulation. 1,2 That of phenomenon related to syncytiotrophoblastic stress is triggering endothelial dysregulation and extreme in fl ammation process, and so do the clinical respond related, such as: hypertension, proteinuria, edema, convulsion, cerebral edema, acute renal failure, acute liver dysfunction, thrombocytopenia (which are as the maternal complications) and fetal growth restriction, preterm delivery, still birth (which are as the fetal complications). 3 Fetal growth restriction (FGR) which could be develop solely or as one entity of early-onset preeclampsia is mostly caused by the poor attitude of extravillous trophoblast cells (EVT) in doing its work on maternal spiral artery remodeling process. 4 As we can see clear from the large data of scienti fi c evidence, the only signi fi cant modality to prevent FGR until recent is by giving low-dose aspirin before 16 weeks of gestational age in selected pregnancies with high resistance index of uterine artery shown by doppler velocimetry ultrasound. 5 Beyond that, only timely delivery after series of close monitoring that will give better perinatal outcome. 6 This will often end with preterm delivery, which increases the percentage of preterm birth in general. 6 In the placenta accreta spectrum (PAS) is a condition where the trophoblast invasion is too aggressive. The development of PAS is a complex multifactorial process related to the combination of decidual-myometrial (as the results of previous c-section or other gynecological surgery), absence the basal plate","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41722147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.32771/inajog.v10i3.1572
C. Yeni, Hafni Handayani, Aulia Nasir, Ima Indirayani, Rezania Razali
Objective: To determine the relationship between the history of cesarean section and the incidence of placenta accreta in Dr. Zainoel Abidin Hospital Banda Aceh. Methods: The data collection method used was secondary data collection which was assessed through retrospective medical records. Sampling in this study using total sampling method. The results of the study were processed using the chi square statistical test on 781 research samples that were collected from period April 2019 - April 2020. Results: The results obtained were 22 respondents (2.8%) experienced placenta accreta where 18 respondents (2.30%) had placenta accreta with a history of CS and 4 respondents (0.51%) placenta accreta without a history of CS. The p value obtained was 0.000 (p value <0.05). In this study, the value of the Risk Estimate (RE) was 6.483 with a Confident Interval (CI) of 95% being (2.21-18.97). Conclusions: There is a very significant relationship between the history of cesarean section and the incidence of placenta accreta at RSUDZA Banda Aceh and mothers with a history of CS have a 6 times greater risk of experiencing placenta accreta. Keywords: cesarean section, placenta accrete. Abstrak Tujuan: Untuk mengetahui hubungan riwayat seksio sesarea dengan kejadian plasenta akreta di Rumah Sakit Umum Daerah Dr. Zainoel Abidin Banda Aceh. Metode: Jenis penelitian ini adalah penelitian analitik dengan desain potong lintang. Metode pengambilan data yang digunakan adalah pengambilan data sekunder yang dinilai melalui rekam medik secara retrospektif. Pengambilan sampel pada penelitian ini menggunakan metode total sampling. Hasil penelitian diolah menggunakan uji statistik chi square terhadap 781 sampel penelitian yang telah dikumpulkan dari data periode April 2019 – April 2020. Hasil: Hasil yang didapatkan sebanyak 22 responden (2,8%) mengalami plasenta akreta dimana 18 responden (2,30%) plasenta akreta dengan riwayat SC dan 4 responden (0,51%) plasenta akreta tanpa riwayat SC. Nilai p value yang didapatkan adalah 0.000 (p value <0,05). Pada penelitian ini didapatkan nilai Risk Estimate (RE) 6,483 dengan Confident Interval (CI) 95% berada (2,21- 18,97). Kesimpulan: Hasil ini menunjukkan terdapat hubungan yang sangat signifikan antara riwayat seksio sesarea dengan kejadian plasenta akreta di RSUDZA Banda Aceh dan ibu dengan riwayat SC memiliki risiko 6 kali lebih besar untuk mengalami plasenta akreta. Kata kunci: plasenta akreta, seksio sesarea.
目的:探讨班达亚齐Zainoel Abidin医院剖宫产史与胎盘增生的关系。方法:采用回顾性病历法进行二次资料收集。本研究采用全抽样方法进行抽样。研究结果对2019年4月至2020年4月收集的781个研究样本进行了卡方统计检验。结果:22例(2.8%)有胎盘增生,18例(2.30%)有胎盘增生伴CS病史,4例(0.51%)无CS病史。所得p值为0.000 (p值<0.05)。本研究的风险估计值(RE)为6.483,95%可信区间(CI)为(2.21 ~ 18.97)。结论:在RSUDZA Banda Aceh,剖宫产史与胎盘增生的发生率有非常显著的关系,有CS史的母亲发生胎盘增生的风险高6倍。关键词:剖宫产;胎盘增生;图juan: Untuk mengetahui hubungan riwayat seksio sesarea dengan kejadian plasenta akreta di Rumah Sakit Umum Daerah Zainoel Abidin Banda Aceh。方法:简体中文:简体中文:简体中文:简体中文:简体中文:简体中文:简体中文:简体中文:简体中文:简体中文:简体中文:简体中文:简体中文。方法:彭甘比兰数据,杨迪古纳坎,阿达拉,彭甘比兰数据,杨迪尼莱,melalui, rekam medik, secara回顾。彭甘比兰样品帕达佩利特依蒙古那坎方法总采样。2019年4月至2020年4月期间,新疆新疆自治区统计卡方共781个样本。Hasil: Hasil yang didapatkan sebanyak 22应答(2,8%),mengalami plasenta akreta dimana 18应答(2,30%)plasenta akreta dengan riwayat SC, 4应答(0,51%)plasenta akreta tanpa riwayat SC. Nilai p值yang didapatkan adalah 0.000 (p值< 0.05)。Pada penelitian ini didapatkan nilai风险估计(RE)为6,483,置信区间(CI)为95%(2,21- 18,97)。Hasil ini menunjukkan terdapat hubungan yang sangat signifikan antara riwayat seksio sesarea dengan kejadian plasenta akreta di RSUDZA Banda Aceh danibu dengan riwayat SC memoriliki risko 6 kali lebih besar untuk mengalami plasenta akreta。质体:质体,质体。
{"title":"The Association betweeen Cesarean Section and Placenta Accreta","authors":"C. Yeni, Hafni Handayani, Aulia Nasir, Ima Indirayani, Rezania Razali","doi":"10.32771/inajog.v10i3.1572","DOIUrl":"https://doi.org/10.32771/inajog.v10i3.1572","url":null,"abstract":"Objective: To determine the relationship between the history of cesarean section and the incidence of placenta accreta in Dr. Zainoel Abidin Hospital Banda Aceh. \u0000Methods: The data collection method used was secondary data collection which was assessed through retrospective medical records. Sampling in this study using total sampling method. The results of the study were processed using the chi square statistical test on 781 research samples that were collected from period April 2019 - April 2020. \u0000Results: The results obtained were 22 respondents (2.8%) experienced placenta accreta where 18 respondents (2.30%) had placenta accreta with a history of CS and 4 respondents (0.51%) placenta accreta without a history of CS. The p value obtained was 0.000 (p value <0.05). In this study, the value of the Risk Estimate (RE) was 6.483 with a Confident Interval (CI) of 95% being (2.21-18.97). \u0000Conclusions: There is a very significant relationship between the history of cesarean section and the incidence of placenta accreta at RSUDZA Banda Aceh and mothers with a history of CS have a 6 times greater risk of experiencing placenta accreta. \u0000Keywords: cesarean section, placenta accrete. \u0000 \u0000Abstrak \u0000Tujuan: Untuk mengetahui hubungan riwayat seksio sesarea dengan kejadian plasenta akreta di Rumah Sakit Umum Daerah Dr. Zainoel Abidin Banda Aceh. \u0000Metode: Jenis penelitian ini adalah penelitian analitik dengan desain potong lintang. Metode pengambilan data yang digunakan adalah pengambilan data sekunder yang dinilai melalui rekam medik secara retrospektif. Pengambilan sampel pada penelitian ini menggunakan metode total sampling. Hasil penelitian diolah menggunakan uji statistik chi square terhadap 781 sampel penelitian yang telah dikumpulkan dari data periode April 2019 – April 2020. \u0000Hasil: Hasil yang didapatkan sebanyak 22 responden (2,8%) mengalami plasenta akreta dimana 18 responden (2,30%) plasenta akreta dengan riwayat SC dan 4 responden (0,51%) plasenta akreta tanpa riwayat SC. Nilai p value yang didapatkan adalah 0.000 (p value <0,05). Pada penelitian ini didapatkan nilai Risk Estimate (RE) 6,483 dengan Confident Interval (CI) 95% berada (2,21- 18,97). \u0000Kesimpulan: Hasil ini menunjukkan terdapat hubungan yang sangat signifikan antara riwayat seksio sesarea dengan kejadian plasenta akreta di RSUDZA Banda Aceh dan ibu dengan riwayat SC memiliki risiko 6 kali lebih besar untuk mengalami plasenta akreta. \u0000Kata kunci: plasenta akreta, seksio sesarea.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45205263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.32771/inajog.v10i3.1559
Annisa D. P. Hernanto, A. Polim, Vetinly
Objective : To determine whether or not there is a relationship between lifestyle and dysmenorrhea intensity in FKIK Atma Jaya students. Methods : This research is a cross sectional analytic descriptive study with a minimum sample size of 196 students of the FKIK Atma Jaya class 2017-2019. The degree of pain was assessed using the Verbal Multidimensional Scoring System pain scale. Frequency of fast food consumption were assessed with Food Frequency Questionnaire. Frequency of physical activity were assessed with International Physical Activity Questionnaire. The datas were analyzed using the Kolmogorov-Smirnov normality test, the Mann-Whitney U test, and the Kruskal-Wallis test. Results : The highest percentage of menstrual pain was at grade 1 (painful menstruation; rarely disturbed activity; no systemic symptoms; rarely required analgesics) for the VMSS scale (46.3%). The percentage of fast food consumption in this study was 86.1%. The highest percentage of physical activity in the category of moderate physical activity was 56.2%. The results of this study indicates a significant relationship between consumption of fast food and the intensity of dysmenorrhea with p = 0.017. There were no significant relationship between physical activity and the intensity of dysmenorrhea with p = 0.225 Conclusion : Consumption of fast food were related to the intensity of dysmenorrhea, whereas physical activity was not related with the intensity of dysmenorrhea. Keywords : dysmenorrhea, , fast food consumption, lifestyle, physical activity Abstrak Tujuan : Untuk mengetahui ada tidaknya hubungan gaya hidup dengan intensitas dismenore pada mahasiswa FKIK Atma Jaya. Metode : Penelitian ini merupakan penelitian deskriptif analitik cross sectional dengan jumlah sampel minimal 196 mahasiswa FKIK Atma Jaya angkatan 2017-2019. Derajat nyeri dinilai dengan menggunakan skala nyeri Verbal Multidimensional Scoring System. Frekuensi konsumsi makanan cepat saji dinilai dengan Food Frequency Questionnaire. Frekuensi aktivitas fisik dinilai dengan International Physical Activity Questionnaire. Data dianalisis menggunakan uji normalitas Kolmogorov-Smirnov, uji Mann-Whitney U, dan uji Kruskal-Wallis. Hasil : Persentase nyeri haid tertinggi pada derajat 1 (nyeri haid; aktivitas jarang terganggu; tidak ada gejala sistemik; jarang memerlukan analgesik) untuk skala VMSS (46,3%). Persentase konsumsi fast food dalam penelitian ini adalah 86,1%. Persentase aktivitas fisik tertinggi pada kategori aktivitas fisik sedang adalah 56,2%. Hasil penelitian ini menunjukkan adanya hubungan yang signifikan antara konsumsi fast food dengan intensitas dismenore dengan p = 0,017. Tidak ada hubungan yang bermakna antara aktivitas fisik dengan intensitas dismenore dengan p=0,225 Kesimpulan : Konsumsi fast food berhubungan dengan intensitas dismenore, sedangkan aktivitas fisik tidak berhubungan dengan intensitas dismenore. Kata kunci : aktivitas fisik, dismenore, gaya hidup, konsumsi fast f
{"title":"Does Lifestyle Affect Dysmenorrhea Intensity? A Cross-Sectional Study","authors":"Annisa D. P. Hernanto, A. Polim, Vetinly","doi":"10.32771/inajog.v10i3.1559","DOIUrl":"https://doi.org/10.32771/inajog.v10i3.1559","url":null,"abstract":"Objective : To determine whether or not there is a relationship between lifestyle and dysmenorrhea intensity in FKIK Atma Jaya students. \u0000Methods : This research is a cross sectional analytic descriptive study with a minimum sample size of 196 students of the FKIK Atma Jaya class 2017-2019. The degree of pain was assessed using the Verbal Multidimensional Scoring System pain scale. Frequency of fast food consumption were assessed with Food Frequency Questionnaire. Frequency of physical activity were assessed with International Physical Activity Questionnaire. The datas were analyzed using the Kolmogorov-Smirnov normality test, the Mann-Whitney U test, and the Kruskal-Wallis test. \u0000Results : The highest percentage of menstrual pain was at grade 1 (painful menstruation; rarely disturbed activity; no systemic symptoms; rarely required analgesics) for the VMSS scale (46.3%). The percentage of fast food consumption in this study was 86.1%. The highest percentage of physical activity in the category of moderate physical activity was 56.2%. The results of this study indicates a significant relationship between consumption of fast food and the intensity of dysmenorrhea with p = 0.017. There were no significant relationship between physical activity and the intensity of dysmenorrhea with p = 0.225 \u0000Conclusion : Consumption of fast food were related to the intensity of dysmenorrhea, whereas physical activity was not related with the intensity of dysmenorrhea. \u0000Keywords : dysmenorrhea, , fast food consumption, lifestyle, physical activity \u0000 \u0000Abstrak \u0000Tujuan : Untuk mengetahui ada tidaknya hubungan gaya hidup dengan intensitas dismenore pada mahasiswa FKIK Atma Jaya. \u0000Metode : Penelitian ini merupakan penelitian deskriptif analitik cross sectional dengan jumlah sampel minimal 196 mahasiswa FKIK Atma Jaya angkatan 2017-2019. Derajat nyeri dinilai dengan menggunakan skala nyeri Verbal Multidimensional Scoring System. Frekuensi konsumsi makanan cepat saji dinilai dengan Food Frequency Questionnaire. Frekuensi aktivitas fisik dinilai dengan International Physical Activity Questionnaire. Data dianalisis menggunakan uji normalitas Kolmogorov-Smirnov, uji Mann-Whitney U, dan uji Kruskal-Wallis. \u0000Hasil : Persentase nyeri haid tertinggi pada derajat 1 (nyeri haid; aktivitas jarang terganggu; tidak ada gejala sistemik; jarang memerlukan analgesik) untuk skala VMSS (46,3%). Persentase konsumsi fast food dalam penelitian ini adalah 86,1%. Persentase aktivitas fisik tertinggi pada kategori aktivitas fisik sedang adalah 56,2%. Hasil penelitian ini menunjukkan adanya hubungan yang signifikan antara konsumsi fast food dengan intensitas dismenore dengan p = 0,017. Tidak ada hubungan yang bermakna antara aktivitas fisik dengan intensitas dismenore dengan p=0,225 \u0000Kesimpulan : Konsumsi fast food berhubungan dengan intensitas dismenore, sedangkan aktivitas fisik tidak berhubungan dengan intensitas dismenore. \u0000Kata kunci : aktivitas fisik, dismenore, gaya hidup, konsumsi fast f","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48506630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.32771/inajog.v10i3.1595
I Gde S. Winata, Putra A. E. Aricandana
Abstract Objective: Determine the best effectiveness and efficacy between EMA and EMACO for patients with high-risk GTN. Results: GTN patients who received EMA showed remissions as high as 74.4% - 96.6% of cases. The side effects of anemia in EMA were less toxic than EMACO, but it wasn’t the case in neutropenia. Two studies showed that 57,1% and 87% patients relapse within 2 years, while none in 5 years and 7 years follow-ups. Discussion: With EMACO use, it has been observed to result in increased morbidity and increased health care costs and when patients experience complications while staying overnight in the hospital, they are not monitored by a good specialist team. Patients treated with EMACO had more peripheral neuropathy as result of vincristine than EMA. The use of EMA certainly requires further evaluation. Conclusion: Patients with High-risk GTN who treated first-line with EMA or EMACO have an excellent prognosis. Both regiments are equally effective. There were differences in treatment scheduling, hospitalization requirements, and toxicity between regimens. Keywords: EMA, EMACO, gestational trophoblastic neoplasia Abstrak: Tujuan: Mengetahui efektivitas dan efikasi terbaik diantara EMA dan EMACO untuk pasien dengan NTG berisiko tinggi. Hasil: Pasien dengan NTG yang menerima EMA menunjukkan remisi setinggi 74.4%-96.6% dari kasus. Efek samping anemia dari EMA lebih tidak toksik dibandingkan EMACO, namun tidak dengan neutropenia. Dua studi menunjukkan bahwa 57.1% dan 87% pasien mengalami kekambuhan dalam 2 tahun, namun tidak ada dalam follow up 5 tahun dan 7 tahun. Diskusi: Dengan penggunaan EMACO, dapat diobservasi bahwa terdapat peningkatan morbiditas dan peningkatan biaya pelayanan kesehatan, dan ketika pasien mengalami komplikasi pada saat rawat inap di rumah sakit, mereka tidak dimonitor oleh tim spesialis yang baik. Pasien yang diterapi dengan EMACO memiliki efek samping neuropati perifer lebih tinggi yang disebabkan oleh vinkristin, dibandingkan EMA. Penggunaan EMA membutuhkan evaluasi lebih lanjut. Kesimpulan: Pasien dengan NTG berisiko tinggi yang diterapi dengan lini pertama EMA atau EMACO mempunya prognosis yang baik. Kedua regimen tersebut efektif. Ada perbedaan dalam penjadwalan terapi, kebutuhan rawat inap dan toksisitas antara regimen, Kata kunci: EMA, EMACO, neoplasia trofoblastik gestasional
{"title":"EMA and EMACO Chemotherapy in High Risk Gestational Trophoblast Disease, which Better?","authors":"I Gde S. Winata, Putra A. E. Aricandana","doi":"10.32771/inajog.v10i3.1595","DOIUrl":"https://doi.org/10.32771/inajog.v10i3.1595","url":null,"abstract":"Abstract \u0000Objective: Determine the best effectiveness and efficacy between EMA and EMACO for patients with high-risk GTN. \u0000Results: GTN patients who received EMA showed remissions as high as 74.4% - 96.6% of cases. The side effects of anemia in EMA were less toxic than EMACO, but it wasn’t the case in neutropenia. Two studies showed that 57,1% and 87% patients relapse within 2 years, while none in 5 years and 7 years follow-ups. \u0000Discussion: With EMACO use, it has been observed to result in increased morbidity and increased health care costs and when patients experience complications while staying overnight in the hospital, they are not monitored by a good specialist team. Patients treated with EMACO had more peripheral neuropathy as result of vincristine than EMA. The use of EMA certainly requires further evaluation. \u0000Conclusion: Patients with High-risk GTN who treated first-line with EMA or EMACO have an excellent prognosis. Both regiments are equally effective. There were differences in treatment scheduling, hospitalization requirements, and toxicity between regimens. \u0000 \u0000Keywords: EMA, EMACO, gestational trophoblastic neoplasia \u0000 \u0000Abstrak: \u0000Tujuan: Mengetahui efektivitas dan efikasi terbaik diantara EMA dan EMACO untuk pasien dengan NTG berisiko tinggi. \u0000Hasil: Pasien dengan NTG yang menerima EMA menunjukkan remisi setinggi 74.4%-96.6% dari kasus. Efek samping anemia dari EMA lebih tidak toksik dibandingkan EMACO, namun tidak dengan neutropenia. Dua studi menunjukkan bahwa 57.1% dan 87% pasien mengalami kekambuhan dalam 2 tahun, namun tidak ada dalam follow up 5 tahun dan 7 tahun. \u0000Diskusi: Dengan penggunaan EMACO, dapat diobservasi bahwa terdapat peningkatan morbiditas dan peningkatan biaya pelayanan kesehatan, dan ketika pasien mengalami komplikasi pada saat rawat inap di rumah sakit, mereka tidak dimonitor oleh tim spesialis yang baik. Pasien yang diterapi dengan EMACO memiliki efek samping neuropati perifer lebih tinggi yang disebabkan oleh vinkristin, dibandingkan EMA. Penggunaan EMA membutuhkan evaluasi lebih lanjut. \u0000Kesimpulan: Pasien dengan NTG berisiko tinggi yang diterapi dengan lini pertama EMA atau EMACO mempunya prognosis yang baik. Kedua regimen tersebut efektif. Ada perbedaan dalam penjadwalan terapi, kebutuhan rawat inap dan toksisitas antara regimen, \u0000Kata kunci: EMA, EMACO, neoplasia trofoblastik gestasional \u0000 \u0000 ","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43867102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.32771/inajog.v10i3.1593
Sofia Al Farizi, E. Ernawati, Ernawaty Ernawaty
Objective: To compare the characteristics of cesarean before and during JKN, also analyzes the factors that influence these differences. Methods: This was a quantitative study with a longitudinal retrospective design and qualitative research used design case studies. The population were delivery women at the Banyuwangi referral hospital before and during JKN. The quantitative data were analyzed firstly by univariable and then bivariable. The bivariable analysis was performed by comparing the prevalence ratio (PR) between two variables. Results: The proportion of cesarean delivery had increased significantly during the implementation of JKN. 50% of maternal deaths before JKN gave birth using cesarean delivery, this proportion increased significantly to 60% during JKN. Indications of fraud committed by health workers to be a factor in increasing the proportion of cesarean delivery. Other contributing factors were repeated cesarean delivery, delayed referral, and the number of obstetric complications. Conclusion: There was an increase in the proportion of cesarean deliveries during the implementation of JKN. BPJS Kesehatan needed to re-evaluate the system they had created so far. The quality of service must be emphasized so that the negative impact on women could be minimized. Keywords: cesarean section, health insurance, maternal mortality. Abstrak Tujuan: Membandingkan karakteristik persalinan sesar sebelum dan selama implementasi JKN, selain itu juga menganalisis faktor-faktor yang berpengaruh. Metode: Studi kuantitatif dengan desain longitudinal retrospective dan studi kualitatif dengan desain case studies. Populasi adalah ibu bersalin di rumah sakit rujukan Kabupaten Banyuwangi sebelum dan selama JKN. Data kuantitatif dianalisis secara univariabel dan bivariabel. Analisis bivariabel dengan membandingkan prevalensi rasio (PR) diantara dua variabel. Hasil: Proporsi persalinan sesar meningkat secara signifikan selama implementasi JKN. 50% ibu yang meninggal bersalin dengan metode sesar, proporsi ini meningkat selama JKN menjadi 60%. Indikasi kecurangan oleh tenaga kesehatan menjadi salah satu faktor yang menyebabkan peningkatan ini. Faktor lain yang berkontribusi adalah persalinan sesar yang berulang, keterlambatan rujukan dan banyakanya komplikasi obstetrik. Kesimpulan: Terdapat peningkatan proporsi persalinan sesar selama implementasi JKN. BPJS Kesehatan perlu mengkaji ulang sistem yang dibuat selama ini. Kualitas pelayanan harus tetap dipertahankan, agar tidak berdampak pada kesehatan ibu. Kata kunci: jaminan kesehatan, kematian ibu, persalinan sesar.
{"title":"Cesarean delivery Characteristics during JKN Implementation","authors":"Sofia Al Farizi, E. Ernawati, Ernawaty Ernawaty","doi":"10.32771/inajog.v10i3.1593","DOIUrl":"https://doi.org/10.32771/inajog.v10i3.1593","url":null,"abstract":"Objective: To compare the characteristics of cesarean before and during JKN, also analyzes the factors that influence these differences. \u0000Methods: This was a quantitative study with a longitudinal retrospective design and qualitative research used design case studies. The population were delivery women at the Banyuwangi referral hospital before and during JKN. The quantitative data were analyzed firstly by univariable and then bivariable. The bivariable analysis was performed by comparing the prevalence ratio (PR) between two variables. \u0000Results: The proportion of cesarean delivery had increased significantly during the implementation of JKN. 50% of maternal deaths before JKN gave birth using cesarean delivery, this proportion increased significantly to 60% during JKN. Indications of fraud committed by health workers to be a factor in increasing the proportion of cesarean delivery. Other contributing factors were repeated cesarean delivery, delayed referral, and the number of obstetric complications. \u0000Conclusion: There was an increase in the proportion of cesarean deliveries during the implementation of JKN. BPJS Kesehatan needed to re-evaluate the system they had created so far. The quality of service must be emphasized so that the negative impact on women could be minimized. \u0000Keywords: cesarean section, health insurance, maternal mortality. \u0000 \u0000Abstrak \u0000Tujuan: Membandingkan karakteristik persalinan sesar sebelum dan selama implementasi JKN, selain itu juga menganalisis faktor-faktor yang berpengaruh. \u0000Metode: Studi kuantitatif dengan desain longitudinal retrospective dan studi kualitatif dengan desain case studies. Populasi adalah ibu bersalin di rumah sakit rujukan Kabupaten Banyuwangi sebelum dan selama JKN. Data kuantitatif dianalisis secara univariabel dan bivariabel. Analisis bivariabel dengan membandingkan prevalensi rasio (PR) diantara dua variabel. \u0000Hasil: Proporsi persalinan sesar meningkat secara signifikan selama implementasi JKN. 50% ibu yang meninggal bersalin dengan metode sesar, proporsi ini meningkat selama JKN menjadi 60%. Indikasi kecurangan oleh tenaga kesehatan menjadi salah satu faktor yang menyebabkan peningkatan ini. Faktor lain yang berkontribusi adalah persalinan sesar yang berulang, keterlambatan rujukan dan banyakanya komplikasi obstetrik. \u0000Kesimpulan: Terdapat peningkatan proporsi persalinan sesar selama implementasi JKN. BPJS Kesehatan perlu mengkaji ulang sistem yang dibuat selama ini. Kualitas pelayanan harus tetap dipertahankan, agar tidak berdampak pada kesehatan ibu. \u0000Kata kunci: jaminan kesehatan, kematian ibu, persalinan sesar.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46383645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.32771/inajog.v10i3.1682
Muharam Natadisastra, Yohanes Alda, A. Meutia
Objective: This study examined the correlation of the type of surgery and adherence to the clinical pathway corresponding to the national guidelines in terms of quality and cost control. Methods : Quantitative economic evaluation was conducted to assess the type of surgery and adherence to clinical pathways in terms of quality and cost control. The data were analyzed using the chi-square or Mann–Whitney test. Results : Of the sample of 82 patients who had undergone laparoscopy or laparotomy, 54.9% had a laparoscopic procedure, while 45.1% had undergone laparotomy ; only 25.6% of the case procedures adhered to the clinical pathway. In general, it can be interpreted that, in a laparoscopy procedure, the potential risk that a mismatch will occur in quality control is up to 32 times that of a laparotomy procedure. Moreover, good adherence to the clinical pathway does not correlate with good cost control. Overall, of the 82 cases, only three (3.7%) showed a good fit for both quality control and cost control. Conclusions : The type of surgery correlates with quality and cost control, whereas adherence to the clinical pathway does not correlate with either quality or cost control. Keywords: Laparotomy, Laparoscopy, surgery, endometriosis, national health insurance Abstrak Tujuan: Studi ini menguji korelasi jenis operasi dan kepatuhan terhadap jalur klinis yang sesuai dengan pedoman nasional dalam hal kontrol kualitas dan biaya. Metode: Evaluasi ekonomi kuantitatif dilakukan untuk menilai jenis operasi dan kepatuhan terhadap jalur klinis dalam hal kualitas dan pengendalian biaya. Data dianalisis menggunakan uji chi-square atau Mann-Whitney. Hasil: Dari sampel 82 pasien yang pernah menjalani laparoskopi atau laparotomi, 54,9% menjalani prosedur laparoskopi, sedangkan 45,1% pernah menjalani laparotomi ; hanya 25,6% dari prosedur kasus yang mengikuti jalur klinis. Secara umum dapat diartikan bahwa, dalam prosedur laparoskopi, potensi risiko terjadinya ketidaksesuaian dalam kontrol kualitas adalah hingga 32 kali lipat dari prosedur laparotomi. Selain itu, kepatuhan yang baik terhadap jalur klinis tidak berkorelasi dengan pengendalian biaya yang baik. Secara keseluruhan, dari 82 kasus, hanya tiga (3,7%) yang menunjukkan kesesuaian yang baik untuk pengendalian kualitas dan pengendalian biaya. Kesimpulan: Jenis pembedahan berkorelasi dengan kualitas dan pengendalian biaya, sedangkan kepatuhan terhadap jalur klinis tidak berkorelasi dengan kualitas atau pengendalian biaya. Kata kunci: Laparotomi, Laparoskopi, pembedahan, endometriosis, jaminan kesehatan nasional
目的:探讨手术类型与遵守符合国家指南的临床路径在质量和成本控制方面的相关性。方法:采用定量经济评价方法,从质量和成本控制两方面评价手术类型和对临床路径的依从性。使用卡方检验或Mann-Whitney检验对数据进行分析。结果:82例行腹腔镜或开腹手术的患者中,54.9%行腹腔镜手术,45.1%行开腹手术;只有25.6%的病例程序遵循临床路径。总的来说,可以解释为,在腹腔镜手术中,质量控制不匹配的潜在风险是剖腹手术的32倍。此外,对临床路径的良好坚持与良好的成本控制并不相关。总体而言,在82个案例中,只有3个(3.7%)在质量控制和成本控制方面表现良好。结论:手术类型与质量和成本控制相关,而坚持临床路径与质量和成本控制无关。【关键词】剖腹手术,腹腔镜,手术,子宫内膜异位症,全民健康保险【摘要】图juan:研究menguji korelasi, jenis, operasi, kepatuhan, terhadap, jalur, klinis, yang, sesai, dengan, pedoman,国家糖尿病控制,kualitas, dan biaya。方法:对中国经济发展的经济计量方法进行了评价,并对中国经济发展的经济计量方法进行了分析。数据分析:menggunakan uji卡方atau Mann-Whitney。Hasil: Dari样本82例,pasien yang pernah menjalani腹腔镜,atau腹腔镜,54.9%,menjalani propor腹腔镜,sedangkan 45.1%, pernah menjalani剖腹;韩亚25.6%达里检察官卡苏斯·杨孟吉库蒂·贾鲁尔·克里尼斯。Secara umum dapat diartikan bahwa, dalam procer腹腔镜,potentisi risiko terjadinya ketidaksesaian dalam control kualitas adalah hinga 32 kali lipat dari procer腹腔镜。Selain itu, kepatuhan yang baik, terhadap, jalur klinis, dengan pengen大连biaya yang baik。Secara keseluruhan, dari 82 kasus, hanya tiga (3.7%) yang menunjukkan kesesuaian yang baik untuk pengendalian kualitas dan pengendalian biaya。kespulan: Jenis pengdahan berkorelasi dengan kualitas dan pengendalian biaya, sedangkan kepatuhan terhadap klinis tidak berkorelasi dengan kualitas atau pengendalian biaya。Kata kunci:剖腹手术,腹腔镜,子宫内膜异位症,子宫内膜异位症,子宫内膜异位症
{"title":"How the Type of Surgery and Adherence to the Clinical Pathway Correlate with Quality Control and Cost Control in Endometriosis Surgery","authors":"Muharam Natadisastra, Yohanes Alda, A. Meutia","doi":"10.32771/inajog.v10i3.1682","DOIUrl":"https://doi.org/10.32771/inajog.v10i3.1682","url":null,"abstract":"Objective: This study examined the correlation of the type of surgery and adherence to the clinical pathway corresponding to the national guidelines in terms of quality and cost control. \u0000Methods : Quantitative economic evaluation was conducted to assess the type of surgery and adherence to clinical pathways in terms of quality and cost control. The data were analyzed using the chi-square or Mann–Whitney test. \u0000Results : Of the sample of 82 patients who had undergone laparoscopy or laparotomy, 54.9% had a laparoscopic procedure, while 45.1% had undergone laparotomy ; only 25.6% of the case procedures adhered to the clinical pathway. In general, it can be interpreted that, in a laparoscopy procedure, the potential risk that a mismatch will occur in quality control is up to 32 times that of a laparotomy procedure. Moreover, good adherence to the clinical pathway does not correlate with good cost control. Overall, of the 82 cases, only three (3.7%) showed a good fit for both quality control and cost control. \u0000Conclusions : The type of surgery correlates with quality and cost control, whereas adherence to the clinical pathway does not correlate with either quality or cost control. \u0000Keywords: Laparotomy, Laparoscopy, surgery, endometriosis, national health insurance \u0000Abstrak \u0000Tujuan: Studi ini menguji korelasi jenis operasi dan kepatuhan terhadap jalur klinis yang sesuai dengan pedoman nasional dalam hal kontrol kualitas dan biaya. \u0000Metode: Evaluasi ekonomi kuantitatif dilakukan untuk menilai jenis operasi dan kepatuhan terhadap jalur klinis dalam hal kualitas dan pengendalian biaya. Data dianalisis menggunakan uji chi-square atau Mann-Whitney. \u0000Hasil: Dari sampel 82 pasien yang pernah menjalani laparoskopi atau laparotomi, 54,9% menjalani prosedur laparoskopi, sedangkan 45,1% pernah menjalani laparotomi ; hanya 25,6% dari prosedur kasus yang mengikuti jalur klinis. Secara umum dapat diartikan bahwa, dalam prosedur laparoskopi, potensi risiko terjadinya ketidaksesuaian dalam kontrol kualitas adalah hingga 32 kali lipat dari prosedur laparotomi. Selain itu, kepatuhan yang baik terhadap jalur klinis tidak berkorelasi dengan pengendalian biaya yang baik. Secara keseluruhan, dari 82 kasus, hanya tiga (3,7%) yang menunjukkan kesesuaian yang baik untuk pengendalian kualitas dan pengendalian biaya. \u0000Kesimpulan: Jenis pembedahan berkorelasi dengan kualitas dan pengendalian biaya, sedangkan kepatuhan terhadap jalur klinis tidak berkorelasi dengan kualitas atau pengendalian biaya. \u0000Kata kunci: Laparotomi, Laparoskopi, pembedahan, endometriosis, jaminan kesehatan nasional","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44531126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.32771/inajog.v10i3.1576
Reni C. Ibrahim, John Wantania, S. Mongan
Objective: To determine the pattern of germs and antibiotic susceptibility tests in pregnant women related to risk factors for infection in preterm PROM cases, the threat of preterm labor, pathological fluor albus, and prolonged labor in Manado city. Method: This study is a cross-sectional descriptive study. A total of 21 samples were obtained, consisting of six preterm PROM cases, five premature contraction cases, five pathological fluor albus cases, and five prolonged labor cases. The study was conducted in Kandou General Hospital and Affiliated Hospitals, Manado. All patients were informed about the study and signed informed consent. Germ pattern and antibiotics susceptibility data were analyzed. Results: Of 21 samples, the detected microorganisms included Staphylococcus aureus (12), Coagulase-negative staphylococcus (2), mixed microorganisms (Staphylococcus aureus + Candida sp, Coagulase-negative staphylococcus + Candida sp), Bacillus sp and Candida sp. The susceptible and safe antibiotics for pregnancy were Ampicillin / Sulbactam and Meropenem. The resistant antibiotics were Ceftriaxone, Tetracycline, and Neomycin. Conclusion: The most common type of bacteria found in pregnant women and women in labor was Staphylococcus aureus. Susceptible and safe antibiotics for pregnancy were Ampicillin / Sulbactam and Meropenem. Keywords: antibiotic sensitivity test, germ pattern, pregnancy and labor infection. Abstrak Tujuan: Mengetahui pola kuman dan uji sensitivitas antibiotik pada perempuan hamil terkait faktor risiko infeksi pada kasus KPD preterm, ancaman partus prematurus, fluor albus patologis dan partus lama di kota Manado. Metode: Studi ini merupakan studi deskriptif potong lintang. Jumlah sampel yang didapatkan sebesar 21 sampel di mana terbagi pada masing-masing kasus KPD preterm 6 sampel, ancaman partus prematurus 5 sampel, fluor albus patologis 5 sampel dan partus lama 5 sampel. Sampel diambil dari RSUP Prof. Dr. R. D. Kandou Manado dan Rumah Sakit Jejaring di kota Manado yang memenuhi kriteria inklusi dan eksklusi. Semua pasien dijelaskan mengenai prosedur penelitian dan penandatanganan inform consent baru dilakukan pengambilan sampel. Data dianalisis dengan cara deskriptif tentang pola kuman dan uji sensitivitas antibiotik pada kehamilan dan persalinan dengan faktor risiko infeksi. Hasil: Dari 21 sampel, sebaran jenis mikroorganisme diantaranya Staphylococcus areus (12), Staphylococcus non koagulase (2), mikroorganisme campuran (Staphylococcus aureus + Candida sp, Staphylococcus non koagulase + Candida sp), Bacilus sp dan Candida sp. Hasil uji sensitivitas antibiotik yang sensitif dan aman untuk kehamilan di antaranya Ampicillin/Sulbactam dan Meropenem. Hasil uji sensitivitas antibiotik yang resisten adalah Ceftriaxone, Tetracycline dan Neomycin. Kesimpulan: Jenis mikroorganisme paling banyak adalah Staphylococcus aureus. Hasil uji sensitivitas antibiotik yang sensitif dan aman untuk kehamilan di antaranya Ampicillin/Sulbactam
目的:了解万鸦老市早产儿胎膜早破感染危险因素、早产威胁、病理性白斑及延长产程的相关细菌及药敏试验情况。方法:本研究采用横断面描述性研究。共采集标本21例,包括6例早膜早破,5例早缩,5例病理性白斑,5例延长产程。这项研究是在万鸦老的Kandou总医院和附属医院进行的。所有患者都被告知这项研究并签署了知情同意书。分析菌型及抗生素药敏数据。结果:21份样品中检出的微生物包括金黄色葡萄球菌(12株)、凝固酶阴性葡萄球菌(2株)、混合微生物(金黄色葡萄球菌+念珠菌、凝固酶阴性葡萄球菌+念珠菌)、芽孢杆菌和念珠菌。对妊娠敏感且安全的抗生素有氨苄西林/舒巴坦和美罗培南。耐药抗生素为头孢曲松、四环素和新霉素。结论:孕妇和临产妇女中最常见的细菌是金黄色葡萄球菌。敏感和安全的妊娠抗生素是氨苄西林/舒巴坦和美罗培南。关键词:抗生素敏感性试验,菌型,妊娠与产程感染。Abstrak Tujuan: Mengetahui普拉kuman丹里头sensitivitas antibiotik篇perempuan hamil terkait faktor risiko infeksi篇kasus KPD早产,ancaman分娩prematurus,白带patologis丹分娩喇嘛迪哥打万鸦老。学习方法:学习笔记,学习笔记,学习笔记,学习笔记,学习笔记。Jumlah sampel yang didapatkan sebesar 21 sample di mana terbagi pada masing-masing kasus KPD早产6 sample, anaman早产5 sample,白斑病理5 sample,分娩5 sample。Sampel diambil dari RSUP教授Dr. Dr. Kandou Manado dan Rumah Sakit Jejaring di kota Manado yang memmemi标准,包括:Semua pasen dijelaskan mengenai检察官penelitian dan penandatanganan通知同意baru dilakukan pengambilan样本。用数据分析方法分析了人结核菌对人结核菌的敏感性、抗生素帕达·克哈米兰和结核菌对人结核菌的敏感性。Hasil: Dari 21样品,sebaran jenis微生物diantaranya葡萄球菌(12),非koagulase葡萄球菌(2),campuran微生物(金黄色葡萄球菌+念珠菌sp,非koagulase葡萄球菌+念珠菌sp), Bacilus sp dan Candida sp. Hasil usensitivitas抗生素,yang sensitivitas dan untuk khamilan diantaranya氨苄西林/舒巴坦和美罗培南。哈希乌吉对抗生素的敏感性:杨氏耐药阿达拉、头孢曲松、四环素和新霉素。kespulan: Jenis微生物palyak adalah金黄色葡萄球菌。氨苄西林/舒巴坦和美罗培南。临床研究:耐药、耐药、耐药、耐药
{"title":"Germ Patterns and Antibiotic Susceptibility in Pregnancy and Labor with Risk of Infections","authors":"Reni C. Ibrahim, John Wantania, S. Mongan","doi":"10.32771/inajog.v10i3.1576","DOIUrl":"https://doi.org/10.32771/inajog.v10i3.1576","url":null,"abstract":"Objective: To determine the pattern of germs and antibiotic susceptibility tests in pregnant women related to risk factors for infection in preterm PROM cases, the threat of preterm labor, pathological fluor albus, and prolonged labor in Manado city. \u0000Method: This study is a cross-sectional descriptive study. A total of 21 samples were obtained, consisting of six preterm PROM cases, five premature contraction cases, five pathological fluor albus cases, and five prolonged labor cases. The study was conducted in Kandou General Hospital and Affiliated Hospitals, Manado. All patients were informed about the study and signed informed consent. Germ pattern and antibiotics susceptibility data were analyzed. \u0000Results: Of 21 samples, the detected microorganisms included Staphylococcus aureus (12), Coagulase-negative staphylococcus (2), mixed microorganisms (Staphylococcus aureus + Candida sp, Coagulase-negative staphylococcus + Candida sp), Bacillus sp and Candida sp. The susceptible and safe antibiotics for pregnancy were Ampicillin / Sulbactam and Meropenem. The resistant antibiotics were Ceftriaxone, Tetracycline, and Neomycin. \u0000Conclusion: The most common type of bacteria found in pregnant women and women in labor was Staphylococcus aureus. Susceptible and safe antibiotics for pregnancy were Ampicillin / Sulbactam and Meropenem. \u0000Keywords: antibiotic sensitivity test, germ pattern, pregnancy and labor infection. \u0000 \u0000Abstrak \u0000Tujuan: Mengetahui pola kuman dan uji sensitivitas antibiotik pada perempuan hamil terkait faktor risiko infeksi pada kasus KPD preterm, ancaman partus prematurus, fluor albus patologis dan partus lama di kota Manado. \u0000Metode: Studi ini merupakan studi deskriptif potong lintang. Jumlah sampel yang didapatkan sebesar 21 sampel di mana terbagi pada masing-masing kasus KPD preterm 6 sampel, ancaman partus prematurus 5 sampel, fluor albus patologis 5 sampel dan partus lama 5 sampel. Sampel diambil dari RSUP Prof. Dr. R. D. Kandou Manado dan Rumah Sakit Jejaring di kota Manado yang memenuhi kriteria inklusi dan eksklusi. Semua pasien dijelaskan mengenai prosedur penelitian dan penandatanganan inform consent baru dilakukan pengambilan sampel. Data dianalisis dengan cara deskriptif tentang pola kuman dan uji sensitivitas antibiotik pada kehamilan dan persalinan dengan faktor risiko infeksi. \u0000Hasil: Dari 21 sampel, sebaran jenis mikroorganisme diantaranya Staphylococcus areus (12), Staphylococcus non koagulase (2), mikroorganisme campuran (Staphylococcus aureus + Candida sp, Staphylococcus non koagulase + Candida sp), Bacilus sp dan Candida sp. Hasil uji sensitivitas antibiotik yang sensitif dan aman untuk kehamilan di antaranya Ampicillin/Sulbactam dan Meropenem. Hasil uji sensitivitas antibiotik yang resisten adalah Ceftriaxone, Tetracycline dan Neomycin. \u0000Kesimpulan: Jenis mikroorganisme paling banyak adalah Staphylococcus aureus. Hasil uji sensitivitas antibiotik yang sensitif dan aman untuk kehamilan di antaranya Ampicillin/Sulbactam","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42072997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.32771/inajog.v10i3.1566
A. Kurniawan, M. Ulfa, Raymond Surya, A. Hestiantoro
Abstract Objective: to discuss the clinical pregnancy rate and factors influencing fecundity among endometriosis women having cystectomy laparoscopically who underwent IVF. Methods: The search was conducted on Pubmed®, EBSCOhost®, and Proquest®, Cochrane Library®, ClinicalKey® using MeSH. Case : A 38-years woman, P0A0 come to the gynecology clinic with a chief complaint of primary infertility for eight years. The patient had undergone a bilateral endometrial cyst resected with laparoscopy and failed for two cycles of IVF. What is the clinical pregnancy rate of women that undergo IVF with a history of ovarian endometrioma cystectomy? Results:, There were six articles appropriate to the inclusion criteria and further appraised using the Centre for Evidence-Based Medicine, University of Oxford appraisal tools. The studies consisted of five prognostic studies and one meta-analysis. The studies were appraised for their validity, Importance, and Applicability. Conclusion: The pregnancy rate in patients undergoing IVF after ovarian cystectomy ranges from 14%-45.2%. A prudent consideration and carefulness during cystectomy surgery are essential for patients that wish to be fertile. Keywords: clinical pregnancy rate, endometrioma, in vitro fertilization, laparoscopy, ovarian cystectomy Abstrak Tujuan: Untuk menelaah tentang kemungkinan terjadinya kehamilan secara klinis pada perempuan yang menjalani IVF dengan riwayat laparoskopi sistektomi dan faktor-faktor yang mempengaruhi kesuburannya. Metode: Pencarian jurnal dilakukan dengan menggunakan search engine Pubmed®, EBSCOhost®, dan Proquest®, Cochrane Library®, ClinicalKey® menggunakan MeSH. Kasus: Perempuan P0A0 berusia 38 tahun datang ke poliklinik dengan keluhan utama infertilitas selama delapan tahun. Pasien memiliki riwayat kista endometrioma bilateral yang sudah di kistektomi dengan laparoskopi dan dua kali gagal menjalani siklus IVF. Berapa kemungkinan terjadinya kehamilan secara klinis pada perempuan yang menjalani IVF dengan riwayat kistektomi endometrioma? Hasil: Dari hasil pencarian didapatkan enam artikel jurnal yang sesuai dengan kriteria inklusi dan dianalisis lebih lanjut menggunakan telaah kritis Evideence-Based Medicine, University of Oxford. .Terdapat lima jurnal studi prognostic dan satu meta-analisis. Studi-studi tersebut akan ditelaah kritis lebih lanjut berdasarkan validitas, kepentingan, dan aplikabilitasnya Kesimpulan: Kemungkinan terjadinya kehamilan secara klinis pada pasien yang menjalani IVF setelah kistektomi endometrioma ovarium adalah 14%-45,2%. Pertimbangan yang bijaksana dan hati-hati diperlukan untuk melakukan operasi kistektomi pada pasien yang mengalami endometrioma dan ingin tetap subur. Kata kunci: endometrioma, fertilisasi in vitro, kehamilan klinis, kistektomi ovarium, laparoskopi
摘要目的:探讨腹腔镜子宫内膜异位症患者行体外受精的临床妊娠率及影响生育能力的因素。方法:采用MeSH检索Pubmed®、EBSCOhost®、Proquest®、Cochrane Library®、ClinicalKey®。病例:一名38岁女性,P0A0,以原发性不孕症8年为主诉来到妇科诊所。患者接受了腹腔镜切除的双侧子宫内膜囊肿,并失败了两个周期的体外受精。有卵巢子宫内膜异位瘤膀胱切除术史的妇女接受体外受精的临床妊娠率是多少?结果:有6篇文章符合纳入标准,并使用牛津大学循证医学中心的评估工具进行了进一步的评估。这些研究包括5项预后研究和1项荟萃分析。对研究的效度、重要性和适用性进行评价。结论:卵巢囊肿切除术后体外受精患者妊娠率为14% ~ 45.2%。对于希望生育的患者来说,在膀胱切除手术中谨慎的考虑和小心是必不可少的。【关键词】临床妊娠率,子宫内膜异位症,体外受精,腹腔镜,卵巢囊肿切除术【摘要】图娟:Untuk menelaah tentenkemungkinan terjadinya kehamilan secara klinis pada perempuan yang menelaani IVF登干河,腹腔镜,姐妹子宫内膜异位症,因子因子yang menmenagaruhi kesuburannya。方法:检索Pubmed®,EBSCOhost®,dan Proquest®,Cochrane Library®,ClinicalKey®menggunakan MeSH。Kasus: Perempuan P0A0 berusia 38 tahun datang ke poliklinik dengan keluhan utama intilitas selama delapan tahun。子宫内膜异位瘤,双侧阳子丹,双侧阳子丹,双侧阳子丹,双侧阳子丹,双侧阳子丹,双侧阳子丹,双侧阳子丹,双侧阳子丹,双侧阳子丹。Berapa kemungkinan terjadinya kehamilan secara klinis pada perempuan yang menjalani IVF dengan riwayat子宫内膜异位瘤?英国牛津大学临床医学与临床医学杂志:临床医学与临床医学杂志:预后与临床meta分析。研究-研究结果表明,试管婴儿(IVF)子宫内膜异位症(IVF)子宫内膜异位症(IVF)子宫内膜异位症(IVF)子宫内膜异位症(IVF)子宫内膜异位症(IVF)子宫内膜异位症(IVF)发生率为14%- 45.2%。Pertimbangan yang bijaksana dan hati-hati diperlukan untuk melakukan operasi kistektomi paden yang mengalami子宫内膜异位症dan在tetap郊区。Kata kunci:子宫内膜异位症,体外受精,kehamilan klinis,子宫内膜异位症,腹腔镜
{"title":"Clinical Pregnancy Rate in in-Vitro Fertilization (IVF) among Endometrioma Patients Underwent Cystectomy Laparoscopy","authors":"A. Kurniawan, M. Ulfa, Raymond Surya, A. Hestiantoro","doi":"10.32771/inajog.v10i3.1566","DOIUrl":"https://doi.org/10.32771/inajog.v10i3.1566","url":null,"abstract":"Abstract \u0000Objective: to discuss the clinical pregnancy rate and factors influencing fecundity among endometriosis women having cystectomy laparoscopically who underwent IVF. \u0000Methods: The search was conducted on Pubmed®, EBSCOhost®, and Proquest®, Cochrane Library®, ClinicalKey® using MeSH. \u0000Case : A 38-years woman, P0A0 come to the gynecology clinic with a chief complaint of primary infertility for eight years. The patient had undergone a bilateral endometrial cyst resected with laparoscopy and failed for two cycles of IVF. What is the clinical pregnancy rate of women that undergo IVF with a history of ovarian endometrioma cystectomy? \u0000Results:, There were six articles appropriate to the inclusion criteria and further appraised using the Centre for Evidence-Based Medicine, University of Oxford appraisal tools. The studies consisted of five prognostic studies and one meta-analysis. The studies were appraised for their validity, Importance, and Applicability. \u0000Conclusion: The pregnancy rate in patients undergoing IVF after ovarian cystectomy ranges from 14%-45.2%. A prudent consideration and carefulness during cystectomy surgery are essential for patients that wish to be fertile. \u0000Keywords: clinical pregnancy rate, endometrioma, in vitro fertilization, laparoscopy, ovarian cystectomy \u0000 \u0000Abstrak \u0000Tujuan: Untuk menelaah tentang kemungkinan terjadinya kehamilan secara klinis pada perempuan yang menjalani IVF dengan riwayat laparoskopi sistektomi dan faktor-faktor yang mempengaruhi kesuburannya. \u0000Metode: Pencarian jurnal dilakukan dengan menggunakan search engine Pubmed®, EBSCOhost®, dan Proquest®, Cochrane Library®, ClinicalKey® menggunakan MeSH. \u0000Kasus: Perempuan P0A0 berusia 38 tahun datang ke poliklinik dengan keluhan utama infertilitas selama delapan tahun. Pasien memiliki riwayat kista endometrioma bilateral yang sudah di kistektomi dengan laparoskopi dan dua kali gagal menjalani siklus IVF. Berapa kemungkinan terjadinya kehamilan secara klinis pada perempuan yang menjalani IVF dengan riwayat kistektomi endometrioma? \u0000Hasil: Dari hasil pencarian didapatkan enam artikel jurnal yang sesuai dengan kriteria inklusi dan dianalisis lebih lanjut menggunakan telaah kritis Evideence-Based Medicine, University of Oxford. .Terdapat lima jurnal studi prognostic dan satu meta-analisis. Studi-studi tersebut akan ditelaah kritis lebih lanjut berdasarkan validitas, kepentingan, dan aplikabilitasnya \u0000Kesimpulan: Kemungkinan terjadinya kehamilan secara klinis pada pasien yang menjalani IVF setelah kistektomi endometrioma ovarium adalah 14%-45,2%. Pertimbangan yang bijaksana dan hati-hati diperlukan untuk melakukan operasi kistektomi pada pasien yang mengalami endometrioma dan ingin tetap subur. \u0000Kata kunci: endometrioma, fertilisasi in vitro, kehamilan klinis, kistektomi ovarium, laparoskopi","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44808281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-28DOI: 10.32771/inajog.v10i2.1539
A. Hestiantoro, B. Putri, E. R. Gunardi, Y. B. Saroyo, M. Natadisastra
Abstract Objective: to determine which factors influence the rate of oocyte maturation in In Vitro Fertilization (IVF) program. Methods: A retrospective cohort study was conducted using secondary data from IVF participants at the Yasmin Fertility Clinic, Dr. RSUP. Cipto Mangunkusumo, Jakarta, Indonesia during the period January 2019 to December 2020, as recorded in the InaRepromed archive. The variables analyzed were age, body mass index, and hormone levels on day 1, day 7, and day hCG, with oocyte maturation rate as the main outcome. Correlation test was performed between several variables and the level of oocyte maturation rate and followed by multivariate analysis to assess the factors that were closely related to oocyte maturation rate. Results: Data from 52 subjects were collected for the study. Positive correlation was observed between oocyte maturation rate and estradiol on day 7 (r = 0.229), while negative correlation was observed between oocyte maturation rate and progesterone/estradiol ratio on day 7 (r = -0.289) and luteinizing hormone on day 1 (r = -0.265). Multivariate analysis revealed that higher estradiol on day-7 was associated with better oocyte maturation rate (p = 0.047). Conclusion: Higher estradiol level on day 7 was associated with better oocyte maturation rate in IVF. Keywords: Assisted reproductive technology (ART), estradiol, in vitro fertilization (IVF), progesterone. Abstrak Tujuan: untuk menentukan faktor-faktor yang mempengaruhi tingkat pematangan oosit dalam program Fertilisasi InVitro (FIV). Metode: Desain penelitian adalah kohort retrospektif, menggunakan data sekunder peserta bayi tabung Klinik Fertilitas Yasmin, RSUP Dr. Cipto Mangunkusumo, Jakarta, Indonesia selama periode Januari 2019 hingga Desember 2020, yang tercatat di dalam arsip InaRepromed. Variabel yang dianalisis adalah umur, indeks massa tubuh, dan kadar hormon pada hari ke-1, hari ke-7, dan hari ke-hCG, dengan tingkat maturasi oosit sebagai luaran utama. Dilakukan analisis korelasi antara beberapa variabel dengan tingkat maturasi oosit, dan dilanjutkan dengan analisis multivariat untuk menilai faktor-faktor yang berhubungan kuat dengan tingkat maturasi oosit. Hasil: Data dari 52 subjek dikumpulkan untuk penelitian ini. Dijumpai korelasi positif antara tingkat maturasi oosit dan estradiol pada hari ke 7 (r = 0,229), sedangkan korelasi negatif diamati pula antara tingkat maturasi oosit dan rasio progesteron/estradiol pada hari ke 7 (r = -0,289) dan hormon luteinisasi pada hari 1 (r = -0,265). Analisis multivariat mengungkapkan bahwa estradiol yang lebih tinggi pada hari ke-7 dikaitkan dengan tingkat maturasi oosit yang lebih baik (p = 0,047). Kesimpulan: Kadar estradiol yang lebih tinggi pada hari ke 7 dikaitkan dengan tingkat pematangan oosit yang lebih baik pada program FIV. Kata kunci : Teknologi reproduksi berbantu (TRB), estradiol, fertilisasi in vitro (IVF), progesteron.
摘要目的:探讨体外受精(IVF)过程中影响卵母细胞成熟率的因素。方法:一项回顾性队列研究使用来自Yasmin生育诊所RSUP博士的IVF参与者的次要数据进行。InaRepromed档案中记录的2019年1月至2020年12月期间,印度尼西亚雅加达的Cipto Mangunkusumo。分析的变量包括年龄、体重指数、第1天、第7天和第1天hCG的激素水平,以卵母细胞成熟率为主要指标。对多个变量与卵母细胞成熟率水平进行相关性检验,并进行多因素分析,评估与卵母细胞成熟率密切相关的因素。结果:本研究共收集了52名受试者的数据。第7天卵母细胞成熟率与雌二醇呈正相关(r = 0.229),第7天卵母细胞成熟率与孕酮/雌二醇比(r = -0.289)和第1天黄体生成素(r = -0.265)呈负相关(r = -0.265)。多因素分析显示,第7天雌二醇水平升高与卵母细胞成熟率升高相关(p = 0.047)。结论:体外受精第7天雌二醇水平增高与卵母细胞成熟率增高有关。关键词:辅助生殖技术,雌二醇,体外受精,黄体酮杨Abstrak Tujuan:为她menentukan faktor-faktor mempengaruhi tingkat pematangan oosit dalam程序Fertilisasi体外的(fip)。方法:Desain penelitian adalah kohort回顾性分析,在Klinik Fertilitas Yasmin, RSUP Cipto Mangunkusumo博士主持下的menggunakan数据检索,印度尼西亚雅加达,2019年1月至2020年12月期间,yang tercatat di dalam arsime。变量阳分析adalah umur, indeks massa tubuh, dan kadar hormon pada hari ke-1, hari ke-7, dan hari ke-hCG, dengan tingkat maturasi oosit sebagai luaran utama。Dilakukan分析korelasi安塔拉beberapa variabel dengan tingkat maturasi oosit,丹dilanjutkan dengan分析multivariat为她menilai faktor-faktor杨berhubungan夸dengan tingkat maturasi oosit。哈西尔:数据达52学科dikumpulkan untuk penelitian ini。Dijumpai korelasi伴唱键盘安塔拉tingkat maturasi oosit丹雌二醇篇哈里科7 (r = 0229),而korelasi负数diamati普拉安塔拉tingkat maturasi oosit丹rasio progesteron /雌二醇篇哈里科7 (r = -0289)丹荷尔蒙luteinisasi篇哈里1 (r = -0265)。多变量分析:mengungkapkan bahwa estradiol yang lebih tinggi pada hari ke-7 dikaitkan dengan tingkat maturasi osit yang lebih baik (p = 0.047)。【翻译】:Kadar estradiol yang lebih tinggi pagada hake 7 dikaitkan dengan tingkat pematangan and osit yang lebih baiki pagada程序FIV。Kata kunci:生殖技术(TRB),雌二醇,体外受精(IVF),孕激素。
{"title":"Estradiol on Day Seven is a Good Predictor for Oocyte Maturation Rate in In Vitro Fertilization Program","authors":"A. Hestiantoro, B. Putri, E. R. Gunardi, Y. B. Saroyo, M. Natadisastra","doi":"10.32771/inajog.v10i2.1539","DOIUrl":"https://doi.org/10.32771/inajog.v10i2.1539","url":null,"abstract":"Abstract \u0000Objective: to determine which factors influence the rate of oocyte maturation in In Vitro Fertilization (IVF) program. \u0000Methods: A retrospective cohort study was conducted using secondary data from IVF participants at the Yasmin Fertility Clinic, Dr. RSUP. Cipto Mangunkusumo, Jakarta, Indonesia during the period January 2019 to December 2020, as recorded in the InaRepromed archive. The variables analyzed were age, body mass index, and hormone levels on day 1, day 7, and day hCG, with oocyte maturation rate as the main outcome. Correlation test was performed between several variables and the level of oocyte maturation rate and followed by multivariate analysis to assess the factors that were closely related to oocyte maturation rate. \u0000Results: Data from 52 subjects were collected for the study. Positive correlation was observed between oocyte maturation rate and estradiol on day 7 (r = 0.229), while negative correlation was observed between oocyte maturation rate and progesterone/estradiol ratio on day 7 (r = -0.289) and luteinizing hormone on day 1 (r = -0.265). Multivariate analysis revealed that higher estradiol on day-7 was associated with better oocyte maturation rate (p = 0.047). \u0000Conclusion: Higher estradiol level on day 7 was associated with better oocyte maturation rate in IVF. \u0000Keywords: Assisted reproductive technology (ART), estradiol, in vitro fertilization (IVF), progesterone. \u0000 \u0000Abstrak \u0000Tujuan: untuk menentukan faktor-faktor yang mempengaruhi tingkat pematangan oosit dalam program Fertilisasi InVitro (FIV). \u0000Metode: Desain penelitian adalah kohort retrospektif, menggunakan data sekunder peserta bayi tabung Klinik Fertilitas Yasmin, RSUP Dr. Cipto Mangunkusumo, Jakarta, Indonesia selama periode Januari 2019 hingga Desember 2020, yang tercatat di dalam arsip InaRepromed. Variabel yang dianalisis adalah umur, indeks massa tubuh, dan kadar hormon pada hari ke-1, hari ke-7, dan hari ke-hCG, dengan tingkat maturasi oosit sebagai luaran utama. Dilakukan analisis korelasi antara beberapa variabel dengan tingkat maturasi oosit, dan dilanjutkan dengan analisis multivariat untuk menilai faktor-faktor yang berhubungan kuat dengan tingkat maturasi oosit. \u0000Hasil: Data dari 52 subjek dikumpulkan untuk penelitian ini. Dijumpai korelasi positif antara tingkat maturasi oosit dan estradiol pada hari ke 7 (r = 0,229), sedangkan korelasi negatif diamati pula antara tingkat maturasi oosit dan rasio progesteron/estradiol pada hari ke 7 (r = -0,289) dan hormon luteinisasi pada hari 1 (r = -0,265). Analisis multivariat mengungkapkan bahwa estradiol yang lebih tinggi pada hari ke-7 dikaitkan dengan tingkat maturasi oosit yang lebih baik (p = 0,047). \u0000Kesimpulan: Kadar estradiol yang lebih tinggi pada hari ke 7 dikaitkan dengan tingkat pematangan oosit yang lebih baik pada program FIV. \u0000Kata kunci : Teknologi reproduksi berbantu (TRB), estradiol, fertilisasi in vitro (IVF), progesteron.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42562248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}