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Assosiation between Serum Cortisol Levels and Anxiety levels In Elective and Emergency Cesarean Section 选择性剖宫产和急诊剖宫产患者血清皮质醇水平与焦虑水平的关系
Q4 Medicine Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1624
Nadia O. S. Nurdin, John J. E. Wantania, Ronny A. A. Mewengkang
Objective: To detect anxiety before elective and emergency cesarean section. Methods: This study was a cross-sectional study. The number of research samples was 42 samples consisting of 21 pregnant patients with an elective cesarean section plan and 21 pregnant patients with an emergency cesarean section at Prof. RSUP. Dr. R. D. Kandou Hospital Manado and Network Hospital in Manado from March 2021 to June 2021. Anxiety was assessed by examining serum cortisol and anxiety levels according to the Hamilton questionnaire (HAM-A). The data were then analyzed using SPSS version 23.0 software. Results: Cortisol levels were higher in emergency cesarean section (mean 21.590±11.6392) compared to elective cesarean section (mean 10.586±4.9501). Anxiety levels according to HAM-A scores were higher in emergency cesarean section (mean 15.33±7.722) compared to elective cesarean section (mean 7.19±3.614). Conclusion: There was a significant positive correlation between cortisol levels and anxiety levels based on HAM-A scores. Keywords: cesarean section , cortisol, HAM-A score. anxiety, Abstrak Tujuan: Untuk mendeteksi kecemasan sebelum tindakan seksio sesarea elektif dan emergensi. Metode: Penelitian ini merupakan suatu penelitian cross-sectional. Jumlah sampel penelitian 42 sampel terdiri dari 21 pasien hamil dengan rencana seksio sesarea elektif dan 21 pasien hamil dengan rencana seksio sesarea emergensi di RSUP Prof. Dr. R. D. Kandou Manado dan RS Jejaring di Kota Manado dari bulan Maret 2021 sampai bulan Juni 2021. Kecemasan dinilai melalui pemeriksaan kortisol serum dan tingkat kecemasan menurut kusioner Hamilton (HAM-A). Data kemudian dianalisis dengan menggunakan software SPSS versi 23.0. Hasil: Kadar kortisol secara rata-rata lebih tinggi pada seksio sesarea emergensi (mean 21.590±11.6392) dibandingkan dengan seksio sesarea elektif (mean 10.586±4.9501). Tingkat kecemasan menurut skor HAM-A secara rata-rata lebih tinggi pada seksio sesarea emergensi (mean 15.33±7.722) dibandingkan dengan seksio sesarea elektif (mean 7.19±3.614). Kesimpulan: Terdapat korelasi positif bermakna antara kadar kortisol dan tingkat kecemasan berdasarkan skor HAM-A pada semua subjek penelitian. Kata kunci: kortisol, seksio sesarea,  skor HAM-A. kecemasan
目的:了解择期和紧急剖宫产术前的焦虑状况。方法:本研究为横断面研究。研究样本数量为42个样本,包括RSUP教授的21名选择性剖宫产计划孕妇和21名紧急剖宫产孕妇。2021年3月至2021年6月,Manado的R.D.Kandou医生医院和Network医院。根据汉密尔顿问卷(HAM-A),通过检测血清皮质醇和焦虑水平来评估焦虑。然后使用SPSS 23.0版软件对数据进行分析。结果:紧急剖宫产的皮质醇水平(平均21590±116392)高于选择性剖宫产(平均10586±49501)。根据HAM-A评分,紧急剖宫产后的焦虑水平(平均15,33±7722)高于选择性剖腹产(平均7,19±3614)基于HAM-A评分的焦虑水平。关键词:剖宫产,皮质醇,HAM-A评分。焦虑,抽象目的:检测行动前急诊科的择期和急诊。方法:本研究为横断面研究。42个样本的样本数量包括2021年3月至2021年6月在Manado的RSUP教授Dr.R.D.Kandou和放射医院进行的21名有选择性剖切计划的孕妇和21名有急诊剖切面计划的孕妇。通过血清皮质醇和汉密尔顿(HAM-A)应急测试来评估担忧。然后使用SPSS 23.0版软件对数据进行分析。结果:急诊科皮质醇水平(平均21590±116392)平均高于择期(平均10586±49501)。根据HAM-A评分,急诊科皮质醇含量(平均15,33±7722)平均高于选择性(平均7,19±3614)在所有受试者中皮质醇水平和基于HAM-A的急诊率之间。关键词:皮质醇,芝麻切片,HAM-A评分。突发事件
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引用次数: 0
Sexual Function in Female of Reproductive Age Post Total Hysterectomy 全子宫切除术后育龄女性性功能的变化
Q4 Medicine Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1535
Yonathan D Onibala, Bismarck J. Laihad, Rudy A. Lengkong
Background: Sexual intercourse and having offspring are essential in a household to live because they are determinant of marital happiness. Many women reported increasing sexual function after hysterectomy; meanwhile, others complained about sexual dysfunction after the hysterectomy procedure. Objective: To determine the effect of sexual function on women of reproductive age after a total hysterectomy Method: This study is a descriptive retrospective study with a cross-sectional study design. Results: This study is based on the data of 23 samples that met the inclusion criteria. With 11 samples increasing FSFI score, 11 samples with a decreasing of FSFI score and 1 sample had an unchanged sexual function before and after surgery. Then from those 23 samples, 16 samples with Female Sexual Dysfunction (FSD) have FSFI score of less than or equal to 26.55 before surgery, and 17 samples with FSD after surgery. Based on the T-Test, there were significant differences between the Female Sexual Function Index (FSFI) before and after the surgery. Most of the respondents experienced decreasing sexual satisfaction (14 samples), while only five samples experienced increased sexual satisfaction and the other four samples had unchanged sexual satisfaction. In our study, most of the respondents (17 samples) claimed that there were better or decreased pain after the hysterectomy procedure. While there were only three samples that claimed an increase of pain, and only three samples claimed that there was unchanged pain scale. Conclusion: There were changes in sexual function before and after hysterectomy as measured by Female Sexual Function Index (FSFI) Key Words : Sexual function, FSFI, before hysterectomy, after hysterectomy
背景:性交和生育后代在家庭生活中至关重要,因为它们是婚姻幸福的决定因素。许多妇女报告说,子宫切除术后性功能增强;同时,也有人抱怨子宫切除术后性功能障碍。目的:确定全子宫切除术后性功能对育龄妇女的影响方法:本研究是一项描述性回顾性研究,采用横断面研究设计。结果:本研究基于23个符合纳入标准的样本的数据。11个样本的FSFI评分增加,11个样本FSFI评分降低,1个样本在手术前后性功能不变。在这23个样本中,16个患有女性性功能障碍(FSD)的样本在手术前的FSFI评分小于或等于26.55,17个患有FSD的样本在术后。根据T检验,手术前后女性性功能指数(FSFI)存在显著差异。大多数受访者的性满意度下降(14个样本),只有5个样本的性满意度上升,其他4个样本的满意度不变。在我们的研究中,大多数受访者(17个样本)声称子宫切除术后疼痛减轻。而只有三个样本声称疼痛增加,只有三个样品声称疼痛程度没有变化。结论:用女性性功能指数(FSFI)测定子宫切除术前后性功能有变化关键词:性功能、FSFI、子宫切除术前、子宫切除后
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引用次数: 0
The effect of serum magnesium, calcium, and potassium levels on the event of calf muscle cramps, according to the perspective of pregnant women in the third-trimester of pregnancy 血清镁、钙和钾水平对小腿肌肉痉挛事件的影响,根据妊娠晚期孕妇的观点
Q4 Medicine Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1586
Cut N. Maracilu, Cut M. Yeni, H. Hasanuddin, Hilwah Nora, Sarah I. Nainggolan
 Objective: To determine the effect of magnesium, calcium, and potassium levels on calf muscle cramps in third-trimester pregnant women at Dr. Zainoel Abidin Banda Aceh. Methods: This research is an observational analytic study with a case-control method by taking samples using a total sampling technique. The research sample was third-trimester pregnant women (28-40 weeks of gestation) who were treated in the maternity ward for the period September to December 2020. Results: A total of 263 samples were involved in this study where 105 patients (40%) were obese, 229 patients (87%) were housewives, 161 patients (61%) did not experience muscle cramps and samples had magnesium levels below normal as much as 82 people, calcium levels below normal as many as 127 people and potassium levels below normal as many as 2 people. The mean levels of magnesium, calcium, and potassium were 1.8 mg/dL, 8.69 mg/dL, and 4.25 mmol/L, respectively. The results of this study are magnesium levels affect muscle cramps in pregnant women (p-value=0.000), while calcium levels (p-value=0.373) and potassium (p-value=0.062) do not affect muscle cramps in pregnant women. Conclusion: There is a significant effect between magnesium levels on the incidence of calf muscle cramps in third-trimester pregnant women, while calcium and potassium levels do not affect them. Keywords: Muscle Cramps, Magnesium, Calcium, Potassium.
目的:确定Zainoel Abidin Banda Aceh医院镁、钙和钾水平对妊娠晚期孕妇小腿肌肉痉挛的影响。方法:本研究采用病例对照法,采用全抽样技术进行观察分析研究。研究样本为2020年9月至12月在产科病房接受治疗的妊娠晚期孕妇(妊娠28-40周)。结果:本研究共涉及263个样本,其中105名患者(40%)肥胖,229名患者(87%)是家庭主妇,161名患者(61%)没有出现肌肉痉挛,样本中镁水平低于正常水平的多达82人,钙水平低于正常值的多达127人,钾水平低于正常的多达2人。镁、钙和钾的平均水平分别为1.8 mg/dL、8.69 mg/dL和4.25 mmol/L。这项研究的结果是,镁水平会影响孕妇的肌肉痉挛(p值=0.000),而钙水平(p值=0.373)和钾水平(p=0.062)不会影响孕妇的肌痉挛。结论:镁水平对妊娠晚期妇女小腿肌肉痉挛的发生率有显著影响,而钙和钾水平对其没有影响。关键词:肌肉痉挛,镁,钙,钾。
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引用次数: 0
Nutrition versus Great Obstetric Syndrome: A Bridge too Far? 营养与产科综合征:一座太远的桥?
Q4 Medicine Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1856
Hermanto T. Joewono
N/A
不适用
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引用次数: 0
Management of Isolated Tubal Torsion (ALADIN) during Emergency Laparotomy in Infertile Women 不孕妇女急诊剖腹术中孤立性输卵管扭转的处理
Q4 Medicine Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1582
Bella Aprilia, Raymond Surya, Bram Pradipta
Introduction: Isolated tubal torsion (ITT) is rare cases with challenging to diagnose. We would like to report ITT and primary infertility patient which came with acute abdominal pain. Case: A 36 yo female came to Koja Hospital with acute abdominal pain without sign of infections. Ultrasound findings show cystic mass on bilateral adnexal sized 76x28x39 mm and 31x51x43 mm with minimal ascites. During laparotomy, proximal right fallopian tube was torsioned four times clockwise. There was hydrosalping founded on contralateral tube, while right and left ovaries and uterus were normal. We performed salpingectomy. Discussion: The clinical presentation of ITT is non-specific and it has become a challenge to physician to develop preoperative diagnosis. The spectrum of imaging findings may be wide range depending on adnexal pathology, degree of severity, and the duration of adnexal torsion. The recommendation of primary approach to tubal torsion is conservative management considering ALADIN (mALignAncy-Death tissue, INfertility). Conclusion: The diagnosis is rarely be made before operation, due to non-specific clinical symptoms and imaging findings. The considerations to perform conservative management are malignancy, death tissue/necrotic, and infertility.
引言:孤立性输卵管扭转(ITT)是一种诊断困难的罕见病例。我们想报告ITT和原发性不孕患者,他们伴有急性腹痛。病例:一名36岁的女性因急性腹痛来到Koja医院,没有感染迹象。超声检查显示双侧附件上的囊性肿块,大小分别为76x28x39 mm和31x51x43 mm,腹水很少。在剖腹手术中,右输卵管近端顺时针扭转四次。对侧输卵管积水,左右卵巢及子宫正常。我们做了输卵管切除术。讨论:ITT的临床表现是非特异性的,它已经成为医生制定术前诊断的挑战。影像学表现的范围可能很广,这取决于附件病理、严重程度和附件扭转的持续时间。输卵管扭转的主要治疗方法是考虑ALADIN(mALignAncy Death tissue,INfertility)的保守治疗。结论:由于非特异性的临床症状和影像学表现,很少在手术前做出诊断。保守治疗的考虑因素包括恶性肿瘤、死亡组织/坏死和不孕。
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引用次数: 0
Sociodemographic Factors of Elective and Emergency Cesarean Delivery in the Referal Hospital: A cross-sectional study 转诊医院择期和急诊剖宫产的社会人口因素:一项横断面研究
Q4 Medicine Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1613
Restuaji B.K. Umam, N. I. Purnamasari, I. Sudayasa, Juminten Saimin
Objectives: To analyze the correlation between sociodemographic factors and cesarean section delivery at Referral Hospital in Kendari.  Method: This was a cross-sectional study conducted at dr. Ismoyo Hospital in Kendari. Data were obtained from medical records of cesarean section delivery from January to December 2019. Sampling used simple random sampling techniques. Data were analyzed using the Chi-square test. Result: There were 50.5% emergency cesarean and 49.5% elective cesarean. The maternal age was 18-44 years. Most cases are aged 20-35 years (78.5%), have a higher education level (65.1%), employees (53.2%), and  multipara (56.5%). There was a correlation between age and cesarean section (p = 0.027). There was no correlation between education level (p = 0.618), occupation (p = 0.563), and parity (p = 0.365) with cesarean section. Conclusion: There is a correlation between maternal age and cesarean section. Education, counseling, and antenatal care should be done for early detection. Keywords: age, cesarean section, education level, occupation, parity
目的:分析社会人口学因素与肯达里转诊医院剖宫产的相关性。方法:这是在肯达里Ismoyo医生医院进行的一项横断面研究。数据来自2019年1月至12月剖宫产的病历。抽样采用简单的随机抽样技术。数据分析采用卡方检验。结果:急诊剖宫产占50.5%,择期剖宫产占49.5%。产妇年龄18-44岁。以20 ~ 35岁(78.5%)、高学历(65.1%)、在职(53.2%)、多段(56.5%)居多。年龄与剖宫产有相关性(p = 0.027)。教育程度(p = 0.618)、职业(p = 0.563)、胎次(p = 0.365)与剖宫产无相关性。结论:产妇年龄与剖宫产有相关性。应该进行教育、咨询和产前保健,以便及早发现。关键词:年龄,剖宫产,学历,职业,胎次
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引用次数: 0
Level of maternal zinc serum as risk factor of preeclampsia 母亲血清锌水平与子痫前期危险因素的关系
Q4 Medicine Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1616
Tia Kaprianti, Putri Mirani, A. Martadiansyah, P. M. Lestari, Theodorus Theodorus
Objective : To know the relationship of serum zinc levels with preeclampsia (PE) Method: This observational research uses a type of case control research. The population of this study is all pregnant women with a single pregnancy, gestational age of 28-42 weeks who were treated at the Department of Obstetrics and Gynecology of RSUP Dr. Mohammad Hoesin Palembang from August 2020 to November 2020. The study divided into 2 group, a case group of 30 pregnant women with PE and a control group of 60 pregnant women non PE. Serum zinc level examination is performed on all samples that match the research criteria. The data is processed by using SPSS software program version 20.0 Windows. Result: Both case and control groups had no meaningful differences to the general characteristics of the patient. There were significant differences in average zinc levels of maternal serum in both research groups (p=0.013; 43.90 plus-minus 15.79 pg/dL). The value of serum zinc levels that have the best sensitivity and specificity is at 45.5 pg/dL. Conclusion: There is a meaningful relationship between serum zinc levels and PE events. Pregnant women with serum zinc levels greater than or equal to 45.5 pg /dL were significantly at 3.2 times more risk of PE than pregnant women with serum zinc levels less than or equal to 45.5 pg/dL. In this case it is necessary to supplement zinc earlier in pregnancy to reduce the risk of preeclampsia. Keywords: preeclampsia, zinc, case-control studies
目的:了解血清锌水平与先兆子痫(PE)的关系。方法:本观察性研究采用病例对照研究。本研究的人群均为2020年8月至2020年11月在RSUP妇产科Mohammad Hoesin Palembang医生接受治疗的单胎妊娠期28-42周的孕妇。本研究分为两组,一组为30名PE孕妇,另一组为60名非PE孕妇。对符合研究标准的所有样本进行血清锌水平检查。数据处理采用SPSS软件20.0版Windows。结果:病例组和对照组对患者的一般特征没有显著差异。两个研究组的母体血清平均锌水平存在显著差异(p=0.013;43.90±15.79 pg/dL)。具有最佳敏感性和特异性的血清锌水平的值为45.5pg/dL。结论:血清锌水平与PE事件之间存在一定的相关性。血清锌水平大于或等于45.5pg/dL的孕妇患PE的风险是血清锌水平小于或等于45.5 pg/dL孕妇的3.2倍。在这种情况下,有必要在怀孕早期补充锌,以降低先兆子痫的风险。关键词:先兆子痫,锌,病例对照研究
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引用次数: 0
Successful pregnancy after hCG/hMG treatment in an azoospermic male with idiopathic hypogonadotropic hypogonadism hCG/hMG治疗原发性促性腺功能减退症的无精子症男性后成功妊娠
Q4 Medicine Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1604
G. Jeon, C. Park
Idiopathic hypogonadotropic hypogonadism (IHH) is one of the correctable causes of male infertility. Although there have been several previous reports about fertility treatment for IHH, there are no established guidelines of therapeutic method yet. We present an azoospermic male of IHH who succeeded in pregnancy and full term live birth after 18 months of treatment with human chorionic gonadotropin (hCG)/human menopausal gonadotropin (hMG), and then changed his treatment into testosterone replacement therapy to maintain an appropriate male hormone level. This case report shows that a thorough and careful examination of whether it is a reversible cause is necessary and important in the approach to male infertility. In addition, it further proves that, in the case of IHH, a continuous long-term gonadotrophic stimulation therapy contributes to successful pregnancy and may need a testosterone replacement therapy after birth.
特发性促性腺功能减退症(IHH)是男性不育的可纠正原因之一。尽管之前有几篇关于IHH生育治疗的报道,但目前还没有确定的治疗方法指南。我们报告了一名患有IHH的无精子症男性,他在接受人绒毛膜促性腺激素(hCG)/人更年期促性腺素(hMG)治疗18个月后成功怀孕并足月活产,然后将其治疗改为睾酮替代治疗,以保持适当的雄性激素水平。该病例报告表明,彻底而仔细地检查它是否是一种可逆的原因,对于治疗男性不育是必要和重要的。此外,它进一步证明,在IHH的情况下,持续的长期促性腺激素刺激治疗有助于成功怀孕,并且可能需要在出生后进行睾酮替代治疗。
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引用次数: 0
Response of External Radiotherapy Alone in Stage IIB – IIIC Cervical Cancer Patients 单纯外放疗治疗IIB - IIIC期宫颈癌的疗效观察
Q4 Medicine Pub Date : 2022-07-31 DOI: 10.32771/inajog.v10i3.1575
Antonius Wibowo, B. J. Laihad, S. Mongan, Enrico Napitupulu
Objective: To investigate the therapeutic response and toxicity in cervical cancer patients with stage IIB-IIIC who undergo external radiation. Methods: This was a retrospective study using the medical records of the Obstetric Oncology and Radiotherapy Department at Prof. Dr. R. D. Kandou Hospital Manado. The research subjects were stage IIB-IIIC cervical cancer patients who underwent external radiation from September 2016 to December 2020. External radiation was administrated using 60Cobalt. The statistical analysis assessments in this study was carried out using descriptive analysis, while the analysis of the relationship was carried out using the Chi-Square method. The toxicity assessments were carried out from first day started external radiation up until 1 month after the therapy was deemed completed. Results : As many as 413 cervical cancer patients underwent external radiation during the study. However, only 192 cervical cancer patients with stage IIB-IIIC met the inclusion criteria in this study. The complete response to the therapy based on the findings was 65.6%, the partial response was 31.8%, the stable response was 1.6%, and the progressive response was 1%. In statistical analysis there was a significant association between cervical cancer stage and Overall Treatment Time with response to external radiotherapy. However, no significant association between tumor size and histopathological type with response to external radiotherapy. There were hematological toxicity (45.8%), skin toxicity (45.3%), gastrointestinal toxicity (6.3%) and urinary tract toxicity (2.6%). Conclusions: External radiotherapy response was a complete response where there was an association between cervical cancer stage and Overall Treatment Time with response to external radiotherapy, whereas there is no significant association found between the tumor size and histopathological type based on this research's findings. Most toxicity were hematology with complaints of anemia and thrombocytopenia Keywords: cervical cancer, external radiation response, toxicity.   Abstrak   Tujuan: Untuk mengetahui respon terapi dan efek samping pasien kanker serviks stadium IIB-IIIC yang menjalani radioterapi eksterna. Metode: Penelitian ini adalah penelitian deskriptif rektrospektif dengan menggunakan rekam medis Poli Onkologi Kandungan dan Instalasi Radioterapi RSUP Prof. Dr. R. D. Kandou Manado. Subyek penelitian adalah pasien kanker serviks stadium IIB-IIIC yang menjalani radiasi eksterna mulai September 2016 sampai Desember 2020. Radiasi eksterna dilakukan dengan sinar 60Cobalt. Penilaian analisis statistika pada penelitian ini menggunakan analisis deskriptif dan analisis hubungan menggunakan metode Chi Square. Penilaian efek samping dilakukan sejak hari pertama pasien memulai radiasi eksterna sampai 1 bulan setelah dinyatakan selesai menjalani radioterapi eksterna. Hasil: Selama periode penelitian didapatkan 413 pasien kanker serviks yang menjalani radiasi eksterna nam
目的:探讨宫颈癌症ⅡB~ⅢC期患者外照射后的疗效及毒副反应。方法:这是一项回顾性研究,使用了Manado Kandou教授博士医院产科肿瘤和放射治疗科的医疗记录。研究对象为2016年9月至2020年12月接受外照射的癌症IIB-IIIC期患者。使用60Cobalt进行外照射。本研究中的统计分析评估使用描述性分析进行,而关系分析使用卡方法进行。毒性评估从开始外照射的第一天开始进行,直到治疗完成后1个月。结果:多达413名癌症患者在研究期间接受了外照射。然而,在本研究中,只有192名IIB-IIIC期癌症患者符合入选标准。根据研究结果,对治疗的完全缓解率为65.6%,部分缓解率为31.8%,稳定缓解率为1.6%,渐进缓解率为1%。在统计分析中,宫颈癌症分期和总体治疗时间与外部放疗的反应之间存在显著关联。然而,肿瘤大小和组织病理学类型与外部放疗反应之间没有显著关联。血液毒性(45.8%)、皮肤毒性(45.3%)、胃肠道毒性(6.3%)和尿路毒性(2.6%),而基于这项研究的发现,在肿瘤大小和组织病理学类型之间没有发现显著的关联。大多数毒性是血液学,伴有贫血和血小板减少症关键词:宫颈癌症,外照射反应,毒性。Abstrak Tujuan:为了响应并有效地采样IIB-IIIC体育场的无线电服务。方法:这是一个由R.D.Kandou Manado教授博士使用脊髓灰质炎治疗和RSUP放射治疗的替代方案。该项目是在2016年9月至2020年12月期间为IIB-IIIC体育场提供服务的项目。辐射源为60钴。本次项目统计分析采用文字分析法,并采用中心距分析法。在选择进入外部无线电后的1个月内,每天对外部辐射进行有效采样。Hasil:在这段时间里,共有413个公共服务区,而在IIB-IIIC体育场的公共服务区中只有192个,这些公共服务区符合这段时间的标准。合并反应为65.6%,部分反应为31.8%,无变化反应为1.6%,进展反应为1%。统计分析表明,体育场的服务和总体治疗时间与胸骨放射性反应有关,而肿瘤和组织病理学的分析与胸骨放射性响应无关。血液学有效采样率为45.8%,库利特有效采样率(45.3%),胃肠道有效采样率6.3%,尿路有效采样率2.6%。突发事件:外部无线电响应是一个完整的响应,它适用于体育场和服务中心之间的交通枢纽,以及与外部无线电响应相关的总体治疗时间。这与肿瘤和组织病理学之间的关系并不密切。血液学检查的样本主要是贫血和白细胞减少症。Kata kunci:有效的采样,服务,响应辐射。
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引用次数: 0
C-Reactive Protein and Matrix Metalloproteinase-7 in Preterm Premature Rupture of Membranes (PPROM) and Premature Rupture of Membranes (PROM) c -反应蛋白和基质金属蛋白酶-7在早产儿早破膜(PPROM)和早破膜(PROM)中的作用
Q4 Medicine Pub Date : 2022-07-31 DOI: 10.32771/inajog.v10i3.1574
Rajuddin Rajuddin, Tgk Chairannisa Putri, Munawar
Objective: To determine the difference in qualitative serum CRP and MMP-7 levels between PROM and PPROM Methods: Research with a case-control design with premature rupture of membranes in term pregnancy as a control group and preterm pregnancy as a case group conducted in the delivery room of the Regional General Hospital dr. Zainoel Abidin Banda Aceh starting from January 2020. Total number of each group as many as 30 samples that met the inclusion and exclusion criteria by taking venous blood samples to check the levels of qualitative CRP serum and levels of the Metalloproteinase-7 Matrix (MMP-7). Statistical tests for categorical - numerical data groups were tested using independent sample t-test and categorical - categorical data groups were tested using Chi-Square test. Results: A total of 60 samples with 30 PPROM and 30 PROM mothers. There was no statistically significant difference in the qualitative CRP serum result in PROM patients with term and preterm pregnancies. On MMP-7 examination, the mean MMP-7 level of preterm PROM mothers was higher than at term PROM, which was 5.28 mg / L and there was a significant relationship between MMP-7 and qualitative CRP in PROM patients with term pregnancy (p <0.05). Conclusion: There is no significant difference in the value of qualitative CRP and MMP-7 between PPROM and PROM. However, there was a significant association between qualitative serum CRP and plasma MMP-7 in PROM. Keywords: c-reactive protein, matrix metalloproteinase-7,rupture of membranes.   Abstrak Tujuan: Untuk mengetahui perbedaan gambaran serum CRP kualitatif dan kadar MMP-7 antara kehamilan preterm dan aterm dengan ketuban pecah dini di RSUD  Dr. Zainoel Abidin Banda Aceh. Metode: Penelitian dengan desain kasus kontrol dengan ketuban pecah dini kehamilan aterm sebagai kelompok kontrol dan kehamilan preterm sebagai kelompok kasus. yang dilakukan di Kamar Bersalin Rumah Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh pada Januari 2020. Dengan jumlah masing-masing kelompok sebanyak 30 sampel yang memenuhi kriteria inklusi dan eklusi dengan pengambilan sampel darah vena untuk dilakukan pemeriksaan kadar serum CRP kualitatif dan kadar Matrix Metalloproteinase-7 (MMP-7). Uji statistik untuk kelompok data yang bersifat kategorik - numerik diuji menggunakan uji T tidak berpasangan dan pasangan kelompok data yang bersifat kategorik - katergorik akan diuji menggunakan uji Chi-Square. Hasil: Sebanyak 60 penderita KPD dengan 30 Ibu KPD Preterm dan 30 KPD aterm. Tidak dijumpai perbedaan yang bermakna secara statistik gambaran serum CRP kualitatif pada penderita KPD dengan kehamilan aterm dan preterm. Pada pemeriksaan MMP-7 rerata kadar MMP-7 ibu KPD preterm lebih tinggi dibandingkan KPD  aterm yakni senilai 5,28 mg/L dan terdapat hubungan bermakna antara MMP-7 dan CRP kualitatif pada penderita KPD dengan kehamilan aterm (p < 0,05). Kesimpulan: Tidak terdapat perbedaan gambaran signifikan nilai CRP kualitatif dan MMP-7 antara KPD prete
目的:确定PROM和PPROM之间血清CRP和MMP-7定性水平的差异方法:从2020年1月开始,在班达亚齐地区总医院Zainoel Abidin医生的产房进行病例对照设计研究,以足月妊娠胎膜早破为对照组,早产为病例组。每组多达30个样本的总数符合纳入和排除标准,通过静脉血样检查定性CRP血清水平和金属蛋白酶-7基质(MMP-7)水平。分类数字数据组的统计检验采用独立样本t检验,分类数据组采用卡方检验。结果:共有60个样本,其中30个为PPROM,30个为PROM母亲。足月妊娠和早产胎膜早破患者的血清CRP定性结果没有统计学上的显著差异。在MMP-7检查中,早产胎膜早破产妇的MMP-7平均水平高于足月胎膜早出产妇,为5.28mg/L,并且与足月胎膜患者的定性CRP之间存在显著关系(p<0.05)。然而,胎膜早破患者血清CRP和血浆MMP-7之间存在显著相关性。关键词:c-反应蛋白,基质金属蛋白酶-7,膜破裂。摘要目的:确定RSUD中早产和动脉粥样硬化伴早期骨折患者血清CRP图像和MMP-7表达率的差异Zainoel Abidin Banda Aceh。方法:采用病例对照设计,以骨折早孕为对照组,早产为病例组。这是由Zainoel Abidin Banda Aceh医生于2020年1月在公立医院复印室完成的。共有30个样本,每个样本通过静脉抽血进行定性血清CRP和基质金属蛋白酶-7(MMP-7)测试,符合纳入和排除标准。数据组类别的统计测试——使用非配对T检验和一对数据组类别进行数字测试——使用卡方检验进行明确测试。结果:KPD患者多达60例,其中30例为早产产妇,30例为产后产妇。在患有aterm和早产的KPD患者的血清CRP质量成像中没有发现统计学上有意义的差异。在MMP-7检查中,早产KPD母亲的MMP-7比率高于动脉粥样硬化KPD,即5.28mg/L,并且在动脉粥样硬化妊娠的KPD患者中,MMP-7与定性CRP之间存在有意义的关系(p<0.05)。结论:KPD早产组和aterm组的CRP和MMP-7质量值无显著差异。然而,在妊娠晚期儿童早期精神崩溃患者中,定性CRP血清和血浆MMP-7之间存在显著关系。关键词:c-反应蛋白,基质金属蛋白酶-7,早期骨折。
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Indonesian Journal of Obstetrics and Gynecology
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