This observational study aims to examine the ability of an imaging tool in differentiating between anterior chamber angle biometric measurements of closed angle glaucomas and healthy subjects.:This was a hospital based cross-sectional observational study. Seventy five subjects were grouped into three groups of 25 subjects each based on appropriate inclusion and exclusion criteria. Using AS-OCT, major outcome variables measured wereanterior chamber depth, lens thickness, lens vault and anterior opening distance 750 (AOD 750). Intraocular pressure and axial length were also noted.Statistical analysis showed that there was significant difference in IOP(p=0.02), axial length (p=0.0001), lens thickness (p=0.0001) and lens vault among the studied groups.The study results show that in phacomorphicglaucoma, anterior chamber depth was less and lens vault, axial length & angle opening distance 750 were more as compared to acute primary angle closure glaucoma.
{"title":"A study of anterior chamber angle biometric measurements in closed angle glaucomas and healthy subjects using imaging tool","authors":"Sharwan Kumar Bangra, Manish Sharma, Sandeep Parwal","doi":"10.18231/j.ijceo.2024.060","DOIUrl":"https://doi.org/10.18231/j.ijceo.2024.060","url":null,"abstract":"This observational study aims to examine the ability of an imaging tool in differentiating between anterior chamber angle biometric measurements of closed angle glaucomas and healthy subjects.:This was a hospital based cross-sectional observational study. Seventy five subjects were grouped into three groups of 25 subjects each based on appropriate inclusion and exclusion criteria. Using AS-OCT, major outcome variables measured wereanterior chamber depth, lens thickness, lens vault and anterior opening distance 750 (AOD 750). Intraocular pressure and axial length were also noted.Statistical analysis showed that there was significant difference in IOP(p=0.02), axial length (p=0.0001), lens thickness (p=0.0001) and lens vault among the studied groups.The study results show that in phacomorphicglaucoma, anterior chamber depth was less and lens vault, axial length & angle opening distance 750 were more as compared to acute primary angle closure glaucoma.","PeriodicalId":13485,"journal":{"name":"Indian Journal of Clinical and Experimental Ophthalmology","volume":"46 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141645066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Review the incidence of binocular dysfunctions, clinical features, their association with binocular vision disorders and refractive status at a vision therapy clinic of a tertiary eye institute in India. In this retrospective study, the clinical record of all the patients of binocular dysfunction was obtain from Electronic medical record (EMR). We reviewed the record of 527 symptomatic patients with binocular vision dysfunction related problems who were referred between July 2022 to June 2023, to binocular vision therapy clinic. Out of which 393 patients (74.57%) who had accommodative dysfunction were included in the study. Patients with any ocular surgery, manifest strabismus, amblyopia, anisometropia (more than 2.00 dioptres), ocular pathology, neurological disorders, were not included in the review. Prepresbyopic patient also excluded from this study. All clinical assessments were done by one of the two experienced optometrists. Of the 527 symptomatic patients examined, 74% (393 subjects) showed binocular dysfunction. Among the 393 binocular dysfunction patients, most of them diagnose with convergence insufficiency (18.82%), convergence insufficiency with accommodative insufficiency (26.97%), convergence insufficiency with accommodative infacility (23.40%), convergence insufficiency with accommodative excess (19.24%), poor PFV (4.58%), and convergence excess (6.36%).: In conclusion, we have evaluated the binocular vision dysfunctions of a non-presbyobic population. Out of 527 symptomatic patients examined, 74% (393 patients) showed had binocular dysfunctions. Incident CI was more than CE. This study will provide the prevalence data of binocular vision dysfunction. The study will also provide insight into the differences in binocular vision parameters. A diagnosis of binocular dysfunction depends not only on a few clinical findings of some accommodative and binocular investigations but on a whole battery of tests, in order to produce diagnosis of the type of dysfunction of the patient. For this reason optometrists should systematically complement their routine examination with a whole battery of accommodative and binocular tests that would help to avoid the non-detection of these anomalies in daily optometric practice.
{"title":"Clinical profile and associations of binocular vision dysfunction at a vision therapy clinic of a tertiary eye institute in India","authors":"Roshan Kumar Yadav, Sunil Kumar Sah, Himani Chauhan, Prashant Kumar, Akram Ali, Ruby Singh","doi":"10.18231/j.ijceo.2024.054","DOIUrl":"https://doi.org/10.18231/j.ijceo.2024.054","url":null,"abstract":"Review the incidence of binocular dysfunctions, clinical features, their association with binocular vision disorders and refractive status at a vision therapy clinic of a tertiary eye institute in India. In this retrospective study, the clinical record of all the patients of binocular dysfunction was obtain from Electronic medical record (EMR). We reviewed the record of 527 symptomatic patients with binocular vision dysfunction related problems who were referred between July 2022 to June 2023, to binocular vision therapy clinic. Out of which 393 patients (74.57%) who had accommodative dysfunction were included in the study. Patients with any ocular surgery, manifest strabismus, amblyopia, anisometropia (more than 2.00 dioptres), ocular pathology, neurological disorders, were not included in the review. Prepresbyopic patient also excluded from this study. All clinical assessments were done by one of the two experienced optometrists. Of the 527 symptomatic patients examined, 74% (393 subjects) showed binocular dysfunction. Among the 393 binocular dysfunction patients, most of them diagnose with convergence insufficiency (18.82%), convergence insufficiency with accommodative insufficiency (26.97%), convergence insufficiency with accommodative infacility (23.40%), convergence insufficiency with accommodative excess (19.24%), poor PFV (4.58%), and convergence excess (6.36%).: In conclusion, we have evaluated the binocular vision dysfunctions of a non-presbyobic population. Out of 527 symptomatic patients examined, 74% (393 patients) showed had binocular dysfunctions. Incident CI was more than CE. This study will provide the prevalence data of binocular vision dysfunction. The study will also provide insight into the differences in binocular vision parameters. A diagnosis of binocular dysfunction depends not only on a few clinical findings of some accommodative and binocular investigations but on a whole battery of tests, in order to produce diagnosis of the type of dysfunction of the patient. For this reason optometrists should systematically complement their routine examination with a whole battery of accommodative and binocular tests that would help to avoid the non-detection of these anomalies in daily optometric practice.","PeriodicalId":13485,"journal":{"name":"Indian Journal of Clinical and Experimental Ophthalmology","volume":"42 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141645071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.18231/j.ijceo.2024.042
Gaurav Dubey, Nitesh Pradhan, Ravi Ranjan, Jamshed Ali, Pratik Sharma, Shamit Pal, O. S. Kamat
A case control approach was done in which the primary outcome was to measure and to compare detect any significant changes in the macular thickness of normal controls Versus Type II diabetic patients or with their subgroups of with and without diabetic retinopathy and a secondary outcome to correlate the visual acuity of distance and near with central macular thickness. Two hundred ten study subjects were included in this case-control study has been conducted over a pool of overall 210 participants were further divided into 7 groups such as normal controls, no diabetic retinopathy, mild non-proliferative diabetic retinopathy, moderate non-proliferative diabetic retinopathy, severe non-proliferative diabetic retinopathy, proliferative diabetic retinopathy, clinically significant macular edema was taken and each group having 30 patients (60 eyes in each group) using spectral-domain - OCT. Selected participants enrolled using sampling size (n = k{Z+Z}× {s+s}/d) and confidence interval being capped at 95%. An automated algorithm of OCT scanned the central retinal region having a variable thickness in three concentric circles primary central circle 1 mm of the macula. Four major quadrants (superior, nasal, inferior, temporal) was scanned from center (1mm) to inner (3 mm) and an outer circle (6 mm). To evaluate the result, overall 210 participants with each group having 30 patients in 7 groups (mean age 54.54 ± 9.67 years) were analyzed by one way ANOVA and independent sampling T-test method. The results were evenly distributed in terms of gender-wise sampling, duration/severity of the disease, and changes in visual acuity. A substantially increased macular thickness (p <0.05) was observed among severe forms of diabetic retinopathy compared with the control group. This study conclude that the there is an increased in the macular thickness of all quadrants especially in PDR and CSME group which may be masked by changes in vascular permeability triggering thickening of the retinal layers from early to severe diabetic changes of the macula, using optical coherence tomography for diabetic patients Type II with and without diabetic retinopathy. Although central macular thickness and Log Mar visual acuity distance as well as near are moderately strong correlated.
{"title":"Macular thickness comparison in type II diabetic patients using optical coherence tomography: A case control study","authors":"Gaurav Dubey, Nitesh Pradhan, Ravi Ranjan, Jamshed Ali, Pratik Sharma, Shamit Pal, O. S. Kamat","doi":"10.18231/j.ijceo.2024.042","DOIUrl":"https://doi.org/10.18231/j.ijceo.2024.042","url":null,"abstract":"A case control approach was done in which the primary outcome was to measure and to compare detect any significant changes in the macular thickness of normal controls Versus Type II diabetic patients or with their subgroups of with and without diabetic retinopathy and a secondary outcome to correlate the visual acuity of distance and near with central macular thickness. Two hundred ten study subjects were included in this case-control study has been conducted over a pool of overall 210 participants were further divided into 7 groups such as normal controls, no diabetic retinopathy, mild non-proliferative diabetic retinopathy, moderate non-proliferative diabetic retinopathy, severe non-proliferative diabetic retinopathy, proliferative diabetic retinopathy, clinically significant macular edema was taken and each group having 30 patients (60 eyes in each group) using spectral-domain - OCT. Selected participants enrolled using sampling size (n = k{Z+Z}× {s+s}/d) and confidence interval being capped at 95%. An automated algorithm of OCT scanned the central retinal region having a variable thickness in three concentric circles primary central circle 1 mm of the macula. Four major quadrants (superior, nasal, inferior, temporal) was scanned from center (1mm) to inner (3 mm) and an outer circle (6 mm). To evaluate the result, overall 210 participants with each group having 30 patients in 7 groups (mean age 54.54 ± 9.67 years) were analyzed by one way ANOVA and independent sampling T-test method. The results were evenly distributed in terms of gender-wise sampling, duration/severity of the disease, and changes in visual acuity. A substantially increased macular thickness (p <0.05) was observed among severe forms of diabetic retinopathy compared with the control group. This study conclude that the there is an increased in the macular thickness of all quadrants especially in PDR and CSME group which may be masked by changes in vascular permeability triggering thickening of the retinal layers from early to severe diabetic changes of the macula, using optical coherence tomography for diabetic patients Type II with and without diabetic retinopathy. Although central macular thickness and Log Mar visual acuity distance as well as near are moderately strong correlated.","PeriodicalId":13485,"journal":{"name":"Indian Journal of Clinical and Experimental Ophthalmology","volume":"47 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141644602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.18231/j.ijceo.2024.041
Shefali Mazumdar, R. P. Maurya, Alok Gangwar, Jatin Kumar Singh, Adeeba Wahab, Arpit Gupta, Siddhartha Gupta
To assess the results of tenon’s patch grafting (TPG) in corneal perforation and descemetocele ranging from 2 to 5.5 mm with a minimum 12 months follow-up. This study was a prospective interventional study in which 35 eyes with corneal perforation (25, 71.4%) and descemetocele (10, 28.5%) of different sizes (2-5.5mm) were surgically treated with tenon's patch grafting (TPG) by a single surgeon at a tertiary centre. Preoperative, operative, and post-operative data were recorded. The eyes were evaluated over a minimum postoperative period of 12 months. The outcome of TPG was assessed based on the achievement and maintenance of the anatomical integrity of the eye. Statistical analysis was conducted using SPSS. The mean size of the corneal lesions for corneal perforation was (3.1±1.04 mm) and for descemetocele was (2.45±0.42 mm). The most common underlying ocular pathology was infectious keratitis in 23(65.7%) patients. The most common systemic comorbidity was diabetes mellitus in 10 (28.5%) patients. At 12 months postoperative follow-up, the integrity of the globe was maintained in 69% eyes. In the entire post-op follow-up eight Keratoplasty procedures, seven cataract surgeries, two repeat TPG procedures and one evisceration were done as additional surgeries. Tenon’s Patch grafting is a simple, inexpensive and an effective surgical modality for achieving globe integrity with minimal post-operative care in corneal perforation/descemetocele of 2-5mm.
{"title":"Tenon’s patch grafting: An inexpensive technique for managing corneal perforation and descemetocele - Our experience of 12 months post-operative follow-up","authors":"Shefali Mazumdar, R. P. Maurya, Alok Gangwar, Jatin Kumar Singh, Adeeba Wahab, Arpit Gupta, Siddhartha Gupta","doi":"10.18231/j.ijceo.2024.041","DOIUrl":"https://doi.org/10.18231/j.ijceo.2024.041","url":null,"abstract":"To assess the results of tenon’s patch grafting (TPG) in corneal perforation and descemetocele ranging from 2 to 5.5 mm with a minimum 12 months follow-up. This study was a prospective interventional study in which 35 eyes with corneal perforation (25, 71.4%) and descemetocele (10, 28.5%) of different sizes (2-5.5mm) were surgically treated with tenon's patch grafting (TPG) by a single surgeon at a tertiary centre. Preoperative, operative, and post-operative data were recorded. The eyes were evaluated over a minimum postoperative period of 12 months. The outcome of TPG was assessed based on the achievement and maintenance of the anatomical integrity of the eye. Statistical analysis was conducted using SPSS. The mean size of the corneal lesions for corneal perforation was (3.1±1.04 mm) and for descemetocele was (2.45±0.42 mm). The most common underlying ocular pathology was infectious keratitis in 23(65.7%) patients. The most common systemic comorbidity was diabetes mellitus in 10 (28.5%) patients. At 12 months postoperative follow-up, the integrity of the globe was maintained in 69% eyes. In the entire post-op follow-up eight Keratoplasty procedures, seven cataract surgeries, two repeat TPG procedures and one evisceration were done as additional surgeries. Tenon’s Patch grafting is a simple, inexpensive and an effective surgical modality for achieving globe integrity with minimal post-operative care in corneal perforation/descemetocele of 2-5mm.","PeriodicalId":13485,"journal":{"name":"Indian Journal of Clinical and Experimental Ophthalmology","volume":"19 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141649243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.18231/j.ijceo.2024.038
Amit Raj, Ankita Sharma, Prateek Nishant, R. P. Maurya
{"title":"Artificial intelligence in ophthalmology: Current status","authors":"Amit Raj, Ankita Sharma, Prateek Nishant, R. P. Maurya","doi":"10.18231/j.ijceo.2024.038","DOIUrl":"https://doi.org/10.18231/j.ijceo.2024.038","url":null,"abstract":"","PeriodicalId":13485,"journal":{"name":"Indian Journal of Clinical and Experimental Ophthalmology","volume":"37 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141644920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To compare efficacy of bepotastine besilate (1.5%) versus alcaftadine (0.25%) in patients with vernal keratoconjunctivitis.This comparative, randomized, single-blind and prospective study was conducted on 100 patients diagnosed with VKC, who were allocated to receive either of the two treatment groups. Group A received Alcaftdine eye drops once daily, while Group B received bepotastine besilate twice daily for 8 weeks. The efficacy assessment was done at baseline and then at 4 and 8 weeks post-treatment using following parameters - Primary endpoints included clinical symptoms score and clinical signs score and secondary endpoint included upper tarsal conjunctival brush cytology for eosinophil count.Intra-group analysis of clinical symptoms and clinical signs score showed statistically significant reduction in both scores and eosionophil count when compared to baseline values with both the drugs. On inter-group analysis, it was found that there was no statistically significant difference between the two groups in reduction in clinical symptoms and clinical signs score and eosinophil count. This study concluded that both drugs proved equally efficacious in relieving signs and symptoms of VKC. Difference in improvement of signs, symptoms, eosinophil count between both the groups drugs was not statistically significant.
{"title":"Comparison of efficacy of topical bepotastine besilate and alcaftadine in patients with vernal keratoconjunctivitis","authors":"Neha Yadav, S. Sachdeva, Manisha Rathi, Sonia Chhabra, Shreay Vashisth, Dinkar Yadav","doi":"10.18231/j.ijceo.2024.057","DOIUrl":"https://doi.org/10.18231/j.ijceo.2024.057","url":null,"abstract":"To compare efficacy of bepotastine besilate (1.5%) versus alcaftadine (0.25%) in patients with vernal keratoconjunctivitis.This comparative, randomized, single-blind and prospective study was conducted on 100 patients diagnosed with VKC, who were allocated to receive either of the two treatment groups. Group A received Alcaftdine eye drops once daily, while Group B received bepotastine besilate twice daily for 8 weeks. The efficacy assessment was done at baseline and then at 4 and 8 weeks post-treatment using following parameters - Primary endpoints included clinical symptoms score and clinical signs score and secondary endpoint included upper tarsal conjunctival brush cytology for eosinophil count.Intra-group analysis of clinical symptoms and clinical signs score showed statistically significant reduction in both scores and eosionophil count when compared to baseline values with both the drugs. On inter-group analysis, it was found that there was no statistically significant difference between the two groups in reduction in clinical symptoms and clinical signs score and eosinophil count. This study concluded that both drugs proved equally efficacious in relieving signs and symptoms of VKC. Difference in improvement of signs, symptoms, eosinophil count between both the groups drugs was not statistically significant.","PeriodicalId":13485,"journal":{"name":"Indian Journal of Clinical and Experimental Ophthalmology","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141646240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.18231/j.ijceo.2024.052
Maria Pramod, B. Radhakrishnan, Sathish Kumar
This study was conducted to find out the visual outcomes and factors that affect visual outcomes following cataract surgery in diabetic retinopathy patients. : The study included 200 patients, 100 patients with diabetes but without diabetic retinopathy, and 100 patients with diabetic retinopathy for this study. The duration of diabetics will be equal in two groups. Ophthalmic examination included visual acuity, anterior segment, and fundus examination- stage of retinopathy pre and post-operative, evaluation 12 months postoperatively included visual acuity (VA), retinopathy progression, and macular edema incidence.: Postoperative visual acuity increased by 2 or more lines in patients. Progression of retinopathy occurred in 26.5% of eyes after cataract surgery and in 9.5% of non-operated fellow eyes. The most common complication during surgery was intraoperative miosis accounting for 12%. The most common long-term complication after surgery was cystoid macular edema. The most common complication following surgery was corneal edema (19%) Cataract surgery in diabetic patients results in a good visual outcome. However, duration of type 2 diabetes mellitus plays an important role in progression of cataract. Poor control of diabetes mellitus was associated with an earlier onset of diabetic retinopathy, as well as the progression of previously controlled retinopathy. Uncomplicated cataract surgery seems to exacerbate the progression of DR in patients with worse-controlled diabetes.
{"title":"Visual outcome following cataract surgery in diabetic retinopathy patients","authors":"Maria Pramod, B. Radhakrishnan, Sathish Kumar","doi":"10.18231/j.ijceo.2024.052","DOIUrl":"https://doi.org/10.18231/j.ijceo.2024.052","url":null,"abstract":"This study was conducted to find out the visual outcomes and factors that affect visual outcomes following cataract surgery in diabetic retinopathy patients. : The study included 200 patients, 100 patients with diabetes but without diabetic retinopathy, and 100 patients with diabetic retinopathy for this study. The duration of diabetics will be equal in two groups. Ophthalmic examination included visual acuity, anterior segment, and fundus examination- stage of retinopathy pre and post-operative, evaluation 12 months postoperatively included visual acuity (VA), retinopathy progression, and macular edema incidence.: Postoperative visual acuity increased by 2 or more lines in patients. Progression of retinopathy occurred in 26.5% of eyes after cataract surgery and in 9.5% of non-operated fellow eyes. The most common complication during surgery was intraoperative miosis accounting for 12%. The most common long-term complication after surgery was cystoid macular edema. The most common complication following surgery was corneal edema (19%) Cataract surgery in diabetic patients results in a good visual outcome. However, duration of type 2 diabetes mellitus plays an important role in progression of cataract. Poor control of diabetes mellitus was associated with an earlier onset of diabetic retinopathy, as well as the progression of previously controlled retinopathy. Uncomplicated cataract surgery seems to exacerbate the progression of DR in patients with worse-controlled diabetes.","PeriodicalId":13485,"journal":{"name":"Indian Journal of Clinical and Experimental Ophthalmology","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141647407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.18231/j.ijceo.2024.049
Sumalath Sai Keerthi Mathukumalli, N. Mukkamala
: The aim of this study was to evaluate the effect of PCIOL on contrast sensitivity function in patients following Phacoemulsification surgery.This was an analytical observational study done on patients who underwent uneventful phacoemulsification with either hydrophobic or hydrophilic posterior chamber IOL's. Contrast sensitivity function (CSF) was measured preoperatively and postoperatively after 3 months with Pelli-Robson chart and compared. Normally distributed data was analysed using the independent sample t-test for intergroup comparison and for intragroup comparison before and after cataract surgery, paired t-test was used. Out of 50 patients underwent phacoemulsification surgery, 52% were females and 56% were belonged to age group of 51 to 60 years. 25 patients received hydrophobic intraocular lens and other 25 patients received hydrophilic intraocular lens.Postoperative mean contrast sensitivity (1.997 ± 0.01) was found statistically significant (p <0.01) as compared to the preoperative contrast sensitivity (1.556 ± 0.16). Significant improvement in contrast sensitivity was observed after cataract surgery in both the groups (p<0.05).: The reduced contrast sensitivity function due to cataract, improved after surgery. On the other hand, optical properties and the material of IOL has no impact on contrast sensitivity postoperatively.
{"title":"A study of contrast sensitivity in eyes with hydrophobic and hydrophilic acrylic foldable posterior chamber intraocular lens","authors":"Sumalath Sai Keerthi Mathukumalli, N. Mukkamala","doi":"10.18231/j.ijceo.2024.049","DOIUrl":"https://doi.org/10.18231/j.ijceo.2024.049","url":null,"abstract":": The aim of this study was to evaluate the effect of PCIOL on contrast sensitivity function in patients following Phacoemulsification surgery.This was an analytical observational study done on patients who underwent uneventful phacoemulsification with either hydrophobic or hydrophilic posterior chamber IOL's. Contrast sensitivity function (CSF) was measured preoperatively and postoperatively after 3 months with Pelli-Robson chart and compared. Normally distributed data was analysed using the independent sample t-test for intergroup comparison and for intragroup comparison before and after cataract surgery, paired t-test was used. Out of 50 patients underwent phacoemulsification surgery, 52% were females and 56% were belonged to age group of 51 to 60 years. 25 patients received hydrophobic intraocular lens and other 25 patients received hydrophilic intraocular lens.Postoperative mean contrast sensitivity (1.997 ± 0.01) was found statistically significant (p <0.01) as compared to the preoperative contrast sensitivity (1.556 ± 0.16). Significant improvement in contrast sensitivity was observed after cataract surgery in both the groups (p<0.05).: The reduced contrast sensitivity function due to cataract, improved after surgery. On the other hand, optical properties and the material of IOL has no impact on contrast sensitivity postoperatively.","PeriodicalId":13485,"journal":{"name":"Indian Journal of Clinical and Experimental Ophthalmology","volume":"21 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141645855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetic retinopathy and retinal vein occlusion are significant causes of vision loss in patients with diabetes. Emerging evidence suggests that vitamin D deficiency and elevated homocysteine levels may play a role in the pathogenesis of these conditions. This study investigates the serum levels of vitamin D and homocysteine in patients with diabetic retinopathy and retinal vein occlusion to elucidate potential associations.: Diabetic retinopathy (DR) is a sight threatening complications associated with diabetes mellitus. To find the correlation between vitamin D level and homocysteine plasma levels in patients of DR and Retinal Vein Occlusion patients.: Study the level of serum vitamin D and Homocysteine in patients with diabetic retinopathy as well as in retinal vein occlusions. A case control type of study was conducted on 100 cases (70 diabetic retinopathy and 30 retinal vein occlusion) and age matched 100 control. Detailed relevant history and complete ocular examination was done . Serum vitamin D and homocysteine levels were noted. In our study, majority of the patients belonged to & > 60 years in the group of cases of diabetic retinopathy and most of the patients in the control group belonged to 50-60 years and & > 60 years of age group (40%). Mean age in the cases and controls was equal (58.4±8.4)Majority of the patients in both cases (68.6%) and control (67.1%) group were males. Association was found to be statistically significant when chi square test (p = 0.03). The prevalence of hyper homocysteinenemia was also higher in DR group. The prevalence of hyperhomocystinemia was more in cases of diabetic retinopathy compared to controls. The prevalence of vitamin D deficiency was more in cases of diabetic retinopathy compared to controls and the difference was significant.
糖尿病视网膜病变和视网膜静脉闭塞是导致糖尿病患者视力下降的重要原因。新的证据表明，维生素 D 缺乏和同型半胱氨酸水平升高可能在这些病症的发病机制中起作用。本研究调查了糖尿病视网膜病变和视网膜静脉闭塞患者血清中维生素 D 和同型半胱氨酸的水平，以阐明两者之间的潜在联系：糖尿病视网膜病变（DR）是一种威胁视力的糖尿病并发症。为了找出糖尿病视网膜病变患者和视网膜静脉闭塞患者血浆中维生素 D 水平和同型半胱氨酸水平之间的相关性，我们进行了以下研究：研究糖尿病视网膜病变患者和视网膜静脉闭塞患者的血清维生素 D 水平和同型半胱氨酸水平。对 100 名病例（70 名糖尿病视网膜病变患者和 30 名视网膜静脉闭塞患者）和 100 名年龄匹配的对照者进行了病例对照研究。研究人员详细询问了相关病史，并进行了全面的眼部检查。同时还检测了血清维生素 D 和同型半胱氨酸水平。在我们的研究中，糖尿病视网膜病变病例组的大多数患者年龄在 60 岁及以上，对照组的大多数患者年龄在 50-60 岁及以上（40%）。病例组和对照组的平均年龄相同（58.4±8.4），病例组（68.6%）和对照组（67.1%）的大多数患者为男性。经秩方检验（P = 0.03），两者之间的关系具有统计学意义。高同型半胱氨酸血症的发病率在 DR 组中也较高。与对照组相比，糖尿病视网膜病变患者的高同型半胱氨酸血症患病率更高。与对照组相比，糖尿病视网膜病变患者的维生素 D 缺乏症患病率更高，且差异显著。
{"title":"Study of serum vitamin D and homocysteine levels in patients with diabetic retinopathy and retinal vein occlusion","authors":"Shambhavi Sahay, Archana Tadwalkar, Priyanka Menon, Pooja Kumari","doi":"10.18231/j.ijceo.2024.065","DOIUrl":"https://doi.org/10.18231/j.ijceo.2024.065","url":null,"abstract":"Diabetic retinopathy and retinal vein occlusion are significant causes of vision loss in patients with diabetes. Emerging evidence suggests that vitamin D deficiency and elevated homocysteine levels may play a role in the pathogenesis of these conditions. This study investigates the serum levels of vitamin D and homocysteine in patients with diabetic retinopathy and retinal vein occlusion to elucidate potential associations.: Diabetic retinopathy (DR) is a sight threatening complications associated with diabetes mellitus. To find the correlation between vitamin D level and homocysteine plasma levels in patients of DR and Retinal Vein Occlusion patients.: Study the level of serum vitamin D and Homocysteine in patients with diabetic retinopathy as well as in retinal vein occlusions. A case control type of study was conducted on 100 cases (70 diabetic retinopathy and 30 retinal vein occlusion) and age matched 100 control. Detailed relevant history and complete ocular examination was done . Serum vitamin D and homocysteine levels were noted. In our study, majority of the patients belonged to & > 60 years in the group of cases of diabetic retinopathy and most of the patients in the control group belonged to 50-60 years and & > 60 years of age group (40%). Mean age in the cases and controls was equal (58.4±8.4)Majority of the patients in both cases (68.6%) and control (67.1%) group were males. Association was found to be statistically significant when chi square test (p = 0.03). The prevalence of hyper homocysteinenemia was also higher in DR group. The prevalence of hyperhomocystinemia was more in cases of diabetic retinopathy compared to controls. The prevalence of vitamin D deficiency was more in cases of diabetic retinopathy compared to controls and the difference was significant.","PeriodicalId":13485,"journal":{"name":"Indian Journal of Clinical and Experimental Ophthalmology","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141648319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.18231/j.ijceo.2024.047
V. Bhanvadia, Kinjalkumari Jayantibhai Patel, Pinal Patel, Hansa Goswami
: Retinoblastoma is a childhood malignant intraocular tumor, necessitates a comprehensive treatment approach. Chemotherapy plays a crucial role in managing retinoblastoma. This study aims to evaluate and analyze high-risk histopathological features (HRF) in retinoblastoma cases initially treated with enucleation and those undergoing secondary enucleation after chemotherapy in a tertiary centre in western India.: This retrospective study was carried out in the pathology department, encompassing a total of 136 cases with enucleated eyes, spanning the period from Jan 2017 to Mar 2023. In the present study, all slides were retrieved and examined to gather information on demographics, laterality, choroid invasion, optic nerve invasion, anterior chamber invasion, tumor discrimination, chemotherapy effects, and tumor regression.In this study, the predominant presenting complaint was leukocoria (90%), with a slight female preponderance (53%), in comparison to males (47%). Unilateral cases accounted for 96%, while bilateral presentations were observed in 4% of cases. The mean age was 38 months, with 43% of eyes exhibiting significant choroid invasion and 27% showing invasion beyond the post-laminar optic nerve or resection margin. 76 patients (56%) underwent primary enucleation and 60 (44%) had secondary enucleation after chemotherapy. Out of the 60 patients with secondary enucleation, only 21 patients (35%) had HRF.We found late age of presentation of retinoblastoma in developing country like India. Higher incidence of HRFs in primary enucleated eyes than secondary enucleated eyes. Higher number of cases shows complete regression of tumor after chemotherapy.
{"title":"Evaluation of high risk histopathology features in primary and secondary enucleated retinoblastoma-study of 136 cases in tertiary eye hospital","authors":"V. Bhanvadia, Kinjalkumari Jayantibhai Patel, Pinal Patel, Hansa Goswami","doi":"10.18231/j.ijceo.2024.047","DOIUrl":"https://doi.org/10.18231/j.ijceo.2024.047","url":null,"abstract":": Retinoblastoma is a childhood malignant intraocular tumor, necessitates a comprehensive treatment approach. Chemotherapy plays a crucial role in managing retinoblastoma. This study aims to evaluate and analyze high-risk histopathological features (HRF) in retinoblastoma cases initially treated with enucleation and those undergoing secondary enucleation after chemotherapy in a tertiary centre in western India.: This retrospective study was carried out in the pathology department, encompassing a total of 136 cases with enucleated eyes, spanning the period from Jan 2017 to Mar 2023. In the present study, all slides were retrieved and examined to gather information on demographics, laterality, choroid invasion, optic nerve invasion, anterior chamber invasion, tumor discrimination, chemotherapy effects, and tumor regression.In this study, the predominant presenting complaint was leukocoria (90%), with a slight female preponderance (53%), in comparison to males (47%). Unilateral cases accounted for 96%, while bilateral presentations were observed in 4% of cases. The mean age was 38 months, with 43% of eyes exhibiting significant choroid invasion and 27% showing invasion beyond the post-laminar optic nerve or resection margin. 76 patients (56%) underwent primary enucleation and 60 (44%) had secondary enucleation after chemotherapy. Out of the 60 patients with secondary enucleation, only 21 patients (35%) had HRF.We found late age of presentation of retinoblastoma in developing country like India. Higher incidence of HRFs in primary enucleated eyes than secondary enucleated eyes. Higher number of cases shows complete regression of tumor after chemotherapy.","PeriodicalId":13485,"journal":{"name":"Indian Journal of Clinical and Experimental Ophthalmology","volume":"43 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141648891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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