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Experimental models of Acanthamoeba keratitis 棘阿米巴角膜炎实验模型
Pub Date : 2023-12-15 DOI: 10.18231/j.ijceo.2023.095
Sumeeta Khurana, Chayan Sharma
keratitis (AK) is a severe and potentially blinding corneal infection caused by the protozoan . Despite its rare occurrence, AK poses significant challenges in diagnosis, treatment, and management due to its complex pathogenesis and resistance to conventional therapies. Experimental models have played a crucial role in deepening our understanding of the disease and developing novel therapeutic strategies. This abstract review the various experimental models utilized to study keratitis. These models encompass both in vitro and in vivo systems, enabling researchers to simulate the pathogenic processes involved and evaluate potential therapeutic interventions. , models include cell cultures, corneal epithelial cell lines, and three-dimensional corneal constructs. These systems allow the investigation of adhesion, invasion, host immune responses, and drug efficacy. They provide insights into the molecular mechanisms underlying pathogenesis and aid in the screening of potential anti- agents. models, including animal models such as rabbits and mice, mimic the clinical manifestations of AK and provide a platform for assessing disease progression, evaluating host immune responses, and testing therapeutic interventions. These models have been instrumental in elucidating the factors influencing pathogenesis, including host susceptibility, immune responses, and corneal tissue interactions. Overall, experimental models of keratitis have significantly contributed to our understanding of the disease and provided a platform for developing and evaluating novel treatment strategies. The insights gained from these models hold promise for developing more effective therapies, aiming to improve patient outcomes and mitigate the devastating consequences of keratitis.
角膜炎(AK)是由原虫引起的一种严重的、可能致盲的角膜感染。尽管 AK 病例罕见,但由于其发病机制复杂且对传统疗法具有抗药性,因此给诊断、治疗和管理带来了巨大挑战。实验模型在加深我们对该疾病的了解和开发新型治疗策略方面发挥了至关重要的作用。本摘要回顾了用于研究角膜炎的各种实验模型。这些模型包括体外和体内系统,使研究人员能够模拟相关的致病过程并评估潜在的治疗干预措施。这些模型包括细胞培养物、角膜上皮细胞系和三维角膜构建体。这些系统可用于研究粘附、入侵、宿主免疫反应和药物疗效。这些模型,包括兔子和小鼠等动物模型,模拟了 AK 的临床表现,为评估疾病进展、评价宿主免疫反应和测试治疗干预措施提供了一个平台。这些模型有助于阐明影响发病机制的因素,包括宿主易感性、免疫反应和角膜组织相互作用。总之,角膜炎实验模型极大地促进了我们对该疾病的了解,并为开发和评估新型治疗策略提供了平台。从这些模型中获得的知识有望开发出更有效的疗法,从而改善患者的治疗效果,减轻角膜炎的破坏性后果。
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引用次数: 0
Clinical implementation of ocular health findings in different phases of the menstruation cycle - A systematic review 月经周期不同阶段眼部健康检查结果的临床应用 - 系统综述
Pub Date : 2023-12-15 DOI: 10.18231/j.ijceo.2023.091
Animesh Mondal, Nishtha Verma, Sourav Karmakar, Gaurav Kumar Bhardwaj
Menstrual cycles are essential to women's health and play a significant role in their daily lives. While the hormonal changes during the menstrual cycle are recognized, research has focused on investigating their specific effects on ocular and visual characteristics. This review aims to comprehensively explore the potential alterations in ocular parameters and alterations to visual performance throughout the cycle of menstruation. Following a search in various research repositories, including PubMed, Google Scholar, Ovid, and EMBASE, both original and review publications were reviewed, and information was utilized in this study. Studies with changes in Ocular parameters during all three menstrual cycle phases were noted. The reported studies documented only normally menstruating women. This study provided valuable knowledge and awareness of the risk factors for menstrual cycle-related ocular symptoms and changes and the impact of these conditions on women's life. This information can be used to develop evidence-based guidelines for managing menstrual cycle-related ocular problems and their significance in clinical practice.
月经周期对女性的健康至关重要,并在她们的日常生活中发挥着重要作用。虽然人们已经认识到月经周期中荷尔蒙的变化,但研究的重点是调查它们对眼部和视觉特征的具体影响。本综述旨在全面探讨整个月经周期中眼部参数的潜在变化和视觉表现的改变。在PubMed、Google Scholar、Ovid和EMBASE等多个研究资料库中进行搜索后,本研究对原创和综述性出版物进行了审查,并利用了相关信息。我们注意到在所有三个月经周期阶段眼部参数变化的研究。所报告的研究仅记录了月经正常的女性。这项研究提供了有关月经周期相关眼部症状和变化的风险因素及其对女性生活影响的宝贵知识和认识。这些信息可用于制定循证指南,以管理与月经周期相关的眼部问题及其在临床实践中的意义。
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引用次数: 0
Effect of pan retinal photocoagulation on macular ganglion cell - inner plexiform layer and peripapillary retinal nerve fibre layer thickness 泛视网膜光凝对黄斑神经节细胞-内层丛状层和毛周视网膜神经纤维层厚度的影响
Pub Date : 2023-12-15 DOI: 10.18231/j.ijceo.2023.106
P. Mishra, V. Kanaujia, Kumudini Sharma, Prabhaker Mishra
: To determine the effect of pan retinal photocoagulation (PRP) on spectral domain optical coherence tomography (SD OCT) morphologic parameters like macular ganglion cell-inner plexiform layer (GCIPL), peripapillary retinal nerve fibre layer (RNFL) thickness and central macular thickness (CMT) in diabetic retinopathy cases. This is a retrospective study including 52 eyes with severe non-proliferative to proliferative diabetic retinopathy without macular oedema who required PRP. Macular GCIPL, CMT and peripapillary RNFL thickness measured at baseline and at 1-, 6-, 12- and 18-months post PRP with SD OCT. CMT, Macular GCIPL and peripapillary RNFL thickness increased significantly at 1 month (p<0.05), thereafter a decreasing trend noted at 6, 12 and 18 months. At 18 month CMT, GCIPL and RNFL thickness are higher than baseline but not statistically significant except temporal RNFL and Average GCIPL (p<0.05). A significant correlation found between changes in temporal RNFL and average GCIPL thickness (Pearson Correlation coefficient r= 0.652, 0.557, 0.782, 0.624 at 1, 6, 12 and 18 months respectively. P<0.05 for all values) CMT, macular GCIPL and peripapillary RNFL thickness increase following PRP; peaking at month 1 and stabilizing through next 18 months. Macular GCIPL thickness could be a reproducible indicator of temporal RNFL.
:目的:确定泛视网膜光凝(PRP)对糖尿病视网膜病变病例的光谱域光学相干断层扫描(SD OCT)形态学参数,如黄斑神经节细胞-内丛状层(GCIPL)、毛细血管周围视网膜神经纤维层(RNFL)厚度和黄斑中心厚度(CMT)的影响。这是一项回顾性研究,包括 52 例患有严重非增殖性至增殖性糖尿病视网膜病变且无黄斑水肿、需要 PRP 的病例。在基线和 PRP 后 1、6、12 和 18 个月时使用标清 OCT 测量黄斑 GCIPL、CMT 和毛细血管周围 RNFL 厚度。1 个月时,CMT、黄斑 GCIPL 和毛细血管周围 RNFL 厚度明显增加(p<0.05),之后在 6、12 和 18 个月时呈下降趋势。在 18 个月的 CMT 中,GCIPL 和 RNFL 厚度均高于基线,但除了颞部 RNFL 和平均 GCIPL 外(p<0.05),其他均无统计学意义。颞部 RNFL 和平均 GCIPL 厚度的变化之间存在明显的相关性(1、6、12 和 18 个月的皮尔逊相关系数 r= 0.652、0.557、0.782、0.624)。CMT、黄斑 GCIPL 和毛细血管周围 RNFL 厚度在 PRP 后增加;在第 1 个月达到峰值,并在接下来的 18 个月趋于稳定。黄斑 GCIPL 厚度可以作为颞叶 RNFL 的可重复指标。
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引用次数: 0
Novel incision to debulk eyelids in a case of Orbital Periorbital Plexiform Neurofibroma (OPPN): A case report 在一例眶周丛状神经纤维瘤(OPPN)病例中采用新切口剥离眼睑:病例报告
Pub Date : 2023-12-15 DOI: 10.18231/j.ijceo.2023.123
Umesh Kumar, S. Bera, Shikha Jaiswal, K. C. N. Navya, Vivek Vijay Kumar, R. P. Maurya
: Plexiform neurofibroma with neurofibromatosis 1 is a autosomal dominant condition and a relatively rare condition. It is also termed as Von Recklinghausen disease. PN involving the structures like eyelid, orbit, periorbital and facial structures are labelled as orbital-periorbital PN(OPPN). These are slowly progressing lesions and are present since birth but increase in size during childhood and are locally infiltrating in nature.: To describe a lid incision to simultaneously debulk both upper and lower eyelid, preserving the vascularity in a case of Orbital Periorbital Plexiform Neurofibroma (OPPN).: We report a case of 22 year male who presented with a disfiguring swelling of right side of face since childhood. After thorough clinical and radiological evaluation it was diagnosed to be a OPPN. Staged debulking was planned and after stage 1 debulking, tissue was sent for HPE which revealed overgrowth of peripheral nerve components and connective tissue dermis showing infiltrating tumour composed of oval to spindle cells with pleomorphic nuclei and moderate cytoplasm. Staged debulking with lid reduction surgery was performed.: Neurofibroma is a rare entity with plexiform neurofibroma occurring in 5-15% of patients. OPPN infiltrates locally without respecting the anatomical planes but follows the trigeminal nerve distribution usually. Indications for debulking procedure are usually the disfigurement and optimal timing is also not certain because the extent and rate of growth cannot be predicted.: The facial appearance and outcome in patients with OPPN can be significantly improved through lid reduction surgery.
:丛状神经纤维瘤伴神经纤维瘤病 1 是一种常染色体显性遗传病,比较罕见。它也被称为 Von Recklinghausen 病。累及眼睑、眼眶、眶周和面部结构的神经纤维瘤被称为眶周神经纤维瘤(OPPN)。这些病变进展缓慢,出生后即有,但在儿童期会增大,并具有局部浸润的性质:描述在一例眶周丛状神经纤维瘤(OPPN)病例中同时剥离上下眼睑并保留血管的眼睑切口:我们报告了一例 22 岁男性的病例,他自孩提时代起右侧面部就出现了毁容性肿胀。经过全面的临床和放射学评估,确诊为 OPPN。计划进行分期切除,第一期切除后,组织被送去做 HPE,结果发现周围神经成分和结缔组织真皮过度生长,显示浸润性肿瘤由卵圆形至纺锤形细胞组成,细胞核多形,胞浆中等。对肿瘤进行了分期切除,并进行了眼睑缩小手术:神经纤维瘤是一种罕见的肿瘤,丛状神经纤维瘤的发病率为 5-15%。OPPN局部浸润,不尊重解剖平面,但通常沿三叉神经分布。切除手术的指征通常是毁容,最佳时机也不确定,因为无法预测生长的范围和速度。 OPPN 患者的面部外观和效果可通过睑缘缩小手术得到显著改善。
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引用次数: 0
Evaluating surgical outcome of pterygium excision with conjunctival autograft using autologous blood: Can it be a new norm? 评估使用自体血液进行结膜自体移植翼状胬肉切除术的手术效果:它能成为新标准吗?
Pub Date : 2023-12-15 DOI: 10.18231/j.ijceo.2023.116
Snehal Mahadik, Z. S. Saifee, Ayushi Neema
To evaluate the surgical outcome of use of autologous blood as an adhesive agent in pterygium excision with conjunctival auto-grafting. To observe the effectiveness of autologous blood adherence on the scleral bed and to know whether autologous blood technique can be made as a standard procedure in pterygium surgery or not.The present study is a retrospective observational study. The records of 94 cases of primary pterygium surgery done during August 2022- January 2023 were taken. All patients underwent comprehensive ocular examination pertinent to the disease. Pterygium was dissected and remaining subconjunctival pterygium tissue was separated and excised. The conjunctival limbal auto-graft was taken secured in place by autologous blood and dressing done. Follow-up was done on second post operative day,1st week and 1 month. The study displayed excellent surgical outcome with minimal post operative complications, which too resolved in a week. The most common complication was subconjunctival hemorrhage in 38 cases followed by graft edema in 32 cases. Though graft displacement was observed in 4 cases, they were later rearranged successfully. We did not observe even a single graft loss in our study.Pterygium excision with conjunctival auto-grafting with autologous blood is very safe, less time consuming, easy to perform with less learning curve, economical with excellent postoperative outcome and most importantly more patient satisfaction, thus, making it equivalent to or rather superior to other comparable procedures.
评估在翼状胬肉切除术中使用自体血作为粘合剂并进行结膜自体移植的手术效果。观察自体血在巩膜床粘附的效果,了解自体血技术是否可作为翼状胬肉手术的标准程序。本研究是一项回顾性观察研究,收集了2022年8月至2023年1月期间完成的94例原发性翼状胬肉手术记录。所有患者均接受了与疾病相关的全面眼部检查。剥离翼状胬肉,分离并切除剩余的结膜下胬肉组织。用自体血液固定结膜边缘自体移植,并进行包扎。术后第二天、一周和一个月进行随访。研究结果表明,手术效果极佳,术后并发症极少,而且在一周内就得到了解决。最常见的并发症是结膜下出血(38 例),其次是移植物水肿(32 例)。虽然有 4 例移植物移位,但后来都成功地重新排列。翼状胬肉切除术与结膜自体血自体移植术非常安全,耗时少,操作简单,学习曲线短,经济实惠,术后效果极佳,最重要的是患者满意度更高,因此与其他同类手术相比,翼状胬肉切除术更胜一筹。
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引用次数: 0
Trabeculectomy with collagen implant for the treatment of glaucoma 用胶原植入物进行小梁切除术治疗青光眼
Pub Date : 2023-12-15 DOI: 10.18231/j.ijceo.2023.096
S. Kadir, R. P. Maurya, S. M. Noman, Tanima Roy
The goal is to assess the effectiveness and safety of trabeculectomy with collagen implants for glaucoma patients who cannot be managed medically. This research is a case series that intervenes without randomization and focuses on potential outcomes. The study consisted of 76 treated eyes of 76 patients with uncontrollable glaucoma. A thorough examination of the eyes was performed on all patients, and the results were documented. Each patient underwent conventional trabeculectomy surgery using the fornix-based approach. Additionally, a subconjunctival collagen implant known as Ologen was also utilized. We recorded preoperative data such as age, gender, best-corrected visual acuity, intraocular pressure, glaucoma type, and a few preoperative antiglaucoma medications. We recorded the intraocular pressure after surgery, the number of glaucoma medications given after surgery, and any complications that occurred during the postoperative period. Each patient was monitored for a minimum of six months. Before the operation, the average intraocular pressure (IOP) was 34.21 ± 12.5, and the patient took at least two IOP-lowering medications (average 2.3). The postoperative IOP was measured after three months and found to be 13.85±5.42mm Hg, with a p-value of 0.060. On average, the blood pressure decreased by 16.42±6.42 mmHg after six months, with a p-value of 0.056. After six months, it was observed that the medication significantly reduced 1.22 in intraocular pressure (P=<0.001), leading to a notable decrease of 17.79 mmHg. The success rate stood at a commendable 97.36% at the three-month mark, but it reduced to an alarming 88.15% by the last visit. Within just one month after the operation, several complications arose, including three cases of hyphaema, one case of the shallow anterior chamber, and two cases of wound leak. All patients showed gradual improvement with conservative management. However, three of them developed cataracts within three months. For patients who have not responded to topical antiglaucoma medications, to manage intraocular pressure is a dependable and safe surgical procedure that offers an efficient treatment option.
目的是评估对无法通过药物治疗的青光眼患者进行胶原植入小梁切除术的有效性和安全性。这项研究是一项病例系列研究,不进行随机干预,重点关注潜在的结果。该研究包括 76 名无法控制的青光眼患者的 76 只接受过治疗的眼睛。对所有患者的眼睛进行了全面检查,并记录了检查结果。每位患者都接受了传统的小梁切除手术,采用的是穹窿方法。此外,还使用了一种名为 Ologen 的结膜下胶原植入物。我们记录了术前数据,如年龄、性别、最佳矫正视力、眼压、青光眼类型和一些术前抗青光眼药物。我们记录了术后眼压、术后青光眼用药次数以及术后发生的任何并发症。我们对每位患者进行了至少六个月的监测。手术前,患者的平均眼压(IOP)为 34.21 ± 12.5,至少服用两种降眼压药物(平均 2.3 种)。术后三个月测量的眼压为(13.85±5.42)毫米汞柱,P 值为 0.060。六个月后,血压平均下降了 16.42±6.42mmHg,P 值为 0.056。6 个月后,观察到眼压明显降低了 1.22(P=<0.001),显著降低了 17.79 mmHg。三个月时,成功率达到了令人称赞的 97.36%,但在最后一次就诊时,成功率下降到了惊人的 88.15%。术后仅一个月,就出现了几例并发症,包括三例水肿、一例前房变浅和两例伤口渗漏。所有患者都在保守治疗后逐渐好转。然而,其中三人在三个月内患上了白内障。对于局部抗青光眼药物治疗无效的患者,控制眼压是一种可靠、安全的手术方法,是一种有效的治疗选择。
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引用次数: 0
Challenges faced by ophthalmologists during COVID-19 era 眼科医生在 COVID-19 时代面临的挑战
Pub Date : 2023-12-15 DOI: 10.18231/j.ijceo.2023.109
Prajwalli Reddy, Sumeet Deshpande, Shreya Mishra, Swathy Reddy, Zeba Fatima
Aim of this study was to assess the different difficulties North Karnataka's ophthalmologists encountered during the COVID-19 pandemic. A online questionnaire was prepared to evaluate the various difficulties faced by the ophthalmologists following the lockdown period in their respective practice areas. Data was collected from the responding ophthalmologists on Google forms and analyzed using SPSS software. A total number of 160 responses were obtained. Most of them (32.59%) were in the age group 40–50 years and were working in private practice (35%). 78.12% of ophthalmologists returned to performing surgical procedures after a gap of more than a month post-lockdown. 38.12% of the participants reported a decrease in their surgical workload of more than 90% within this time frame. Significant fear of getting infected with COVID-19 in the operation theatres was reported. 65.65% of participants used N-95 masks while working. Revenue generation was affected significantly during this lockdown. : It is quite evident that the eye care practitioners have been affected significantly, with patient and staff safety being the major concerns.
本研究旨在评估北卡纳塔克邦眼科医生在 COVID-19 大流行期间遇到的各种困难。研究人员准备了一份在线问卷,以评估眼科医生在各自执业地区封锁期后所面临的各种困难。我们通过谷歌表格向答复的眼科医生收集数据,并使用 SPSS 软件进行分析。共收到 160 份回复。其中大部分眼科医生(32.59%)的年龄介于 40-50 岁之间,在私人诊所工作(35%)。78.12%的眼科医生在停诊一个多月后重新开始进行手术。38.12%的参与者表示,在这段时间内,他们的手术工作量减少了 90% 以上。据报告,他们非常担心在手术室感染 COVID-19。65.65% 的参与者在工作时使用 N-95 口罩。在封锁期间,创收受到严重影响。 结论:很明显,眼科护理从业人员受到严重影响,病人和员工的安全是他们最关心的问题。
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引用次数: 0
Assessment of stereoacuity (3D vision) using TNO random dot stereo acuity chart in medical undergraduate students: A cross-sectional study 使用 TNO 随机点立体视力表评估医学本科生的立体视力(三维视力):横断面研究
Pub Date : 2023-12-15 DOI: 10.18231/j.ijceo.2023.107
Amari V Hun, Shivani B Jariwala
The study aimed to estimate the level of stereoacuity in medical undergraduate students, factors associated with reduced stereoacuity, and time taken to interpret plates. Cross-sectional study was done at the Medical College of South Gujarat from April 2021 to June 2022, enrolling 400 consenting students. Detailed ocular history was taken; best corrected visual acuity was assessed for distance and near after cycloplegic refraction for cases with subnormal visual acuity and power of glasses documented. Level of Stereopsis was assessed using TNO random dot stereoacuity chart and time taken to read plates 1 and 5 was recorded. Data were entered and appropriate statistical tests were applied. Out of 400 students, 64.25% had a refractive error. Simple myopia was most prevalent refractive error (43.25%), followed by compound myopic astigmatism (19.5%). Seven students had anisometropic amblyopia and two had strabismic amblyopia. 19.75% cases had subnormal stereopsis. Among them, 10.25% cases had simple myopia, 7.25% had high compound myopic astigmatism, 1.75% had anisometropic amblyopia and 0.5% cases had strabismic amblyopia. Average time taken by emmetrope to read plate 1 and plate 5 was 13.93 ± 14.03 and 19.03 ± 20.66 respectively and for cases with refractive errors, time taken was 17.59 ± 13.95 and 27.83 ± 20.77 respectively. This was statistically significant (P <0.05). Most of the students had good stereoacuity as they were already wearing refractive correction. Commonest cause of subnormal stereopsis ware simple myopia, compound myopic astigmatism and amblyopia. Time taken to read the plates is more for refractive error as compared to emmetropes.
该研究旨在估算医学本科生的立体视力水平、与立体视力下降相关的因素以及解读平板所需的时间。横断面研究于 2021 年 4 月至 2022 年 6 月在南古吉拉特医学院进行,共招募了 400 名同意参加的学生。研究人员详细询问了学生的眼部病史;在对视力不正常的学生进行屈光矫正后,对其远近视力进行了最佳矫正视力评估,并记录了眼镜的度数。使用 TNO 随机点立体视图评估立体视水平,并记录阅读图版 1 和 5 所需的时间。数据被输入并进行了适当的统计检验。在 400 名学生中,64.25% 有屈光不正。单纯性近视是最常见的屈光不正(43.25%),其次是复合性近视散光(19.5%)。7 名学生患有各向异性弱视,2 名学生患有斜视性弱视。19.75%的学生立体视不正常。其中,10.25%的学生患有单纯性近视,7.25%的学生患有高度复合性近视散光,1.75%的学生患有各向异性弱视,0.5%的学生患有斜视性弱视。用验光仪读取平板 1 和平板 5 所需的平均时间分别为(13.93 ± 14.03)和(19.03 ± 20.66),而有屈光不正的病例所需的时间分别为(17.59 ± 13.95)和(27.83 ± 20.77)。这具有统计学意义(P <0.05)。大多数学生的立体视力良好,因为他们已经佩戴了屈光矫正眼镜。立体视不正常的常见原因是单纯性近视、复合性近视散光和弱视。屈光不正的学生与弱视的学生相比,读牌所需的时间更长。
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引用次数: 0
Herpetic keratitis with new characterisations - A unique case series highlighting punched-out ulcer margin with lamellar cleavage 具有新特征的疱疹性角膜炎--突出表现为溃疡边缘打孔并伴有片状裂隙的独特病例系列
Pub Date : 2023-12-15 DOI: 10.18231/j.ijceo.2023.121
Parthasarathi Roy, Sarbaraj Nag
Although HSV keratitis is one of the leading infectious causes of blindness world-wide, its misdiagnosis is not infrequent in clinical practise. We present here six eyes of five cases, all of which were initially misdiagnosed as bacterial / fungal ulcers. All these ulcers had some characteristics in common like, overt/ impending sloughing ulcer with punched out margin and clear-cut lamella planar separation. To the best of our knowledge these characterisations of HSV keratitis were not discussed earlier in literature. Diagnosis rested on clinical findings and response to antiviral therapy. A possible pathophysiology based on anatomical distribution of corneal nerves was discussed. Placement of this distinct group of ulcers in the classification of infective HSK, between dendritic, geographical, punctate ulcers at one end of the spectrum and neurotrophic ulcers at the other, and named as 'neuropathic ulcers' is hereby suggested.: Apart from dendritic, geographical, punctate ulcers at one end of the spectrum and neurotrophic ulcers at the other, there seemed to be another distinct group of herpetic ulcers in between. This new group was characterised by sloughing of that area of the cornea, which was innervated by the HSV infected corneal nerve. The process of sloughing might be aggressive or slow and seemed to progress in an orderly fashion. The area of cornea supplied by the affected nerve was separated from normal cornea by a punched-out border of demarcation followed by lamellar cleavage (separation) following the architecture of lamella- planar distribution of the affected corneal nerve. The lamellar separation could be demonstrated by the pooling of fluorescein dye in the cleaved inter lamellar space. Treatment with oral and local Acyclovir established healing.
尽管 HSV 角膜炎是导致全球失明的主要感染性病因之一,但在临床实践中被误诊的情况并不少见。我们在此介绍五例病例中的六只眼睛,这些病例最初都被误诊为细菌/真菌溃疡。所有这些溃疡都有一些共同的特征,如溃疡过度/即将脱落,溃疡边缘打孔,溃疡层平面分离清晰。据我们所知,这些HSV角膜炎的特征在以前的文献中并没有讨论过。诊断取决于临床表现和对抗病毒治疗的反应。根据角膜神经的解剖分布讨论了可能的病理生理学。建议在感染性 HSK 的分类中将这一类溃疡置于树枝状、地域性、点状溃疡和神经营养性溃疡之间,并命名为 "神经病理性溃疡":除了树枝状、地域性、点状溃疡和神经营养性溃疡之外,似乎还有另一类疱疹性溃疡介于两者之间。这一新类型的特点是角膜上受 HSV 感染的角膜神经支配的区域出现蜕皮。角膜脱落的过程可急可缓,似乎有条不紊。受感染的角膜神经所供应的角膜区域与正常角膜之间有一条打孔的分界线,随后角膜板层按照受感染的角膜神经的板层平面分布结构裂开(分离)。板层分离可通过荧光素染料在裂开的板层间隙汇集来证明。经口服和局部阿昔洛韦治疗后,痊愈。
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引用次数: 0
Mental optometry: Perceive to see with the mind’s eye 心理验光:用心灵之眼感知观看
Pub Date : 2023-12-15 DOI: 10.18231/j.ijceo.2023.092
Jamshedi Ali, Gaurav Dubey, Zeba Hayat, Prasenjit Das, Simi Afroz
Mental optometry is a newly recognized word that refers to the interaction of the mind, brain, and sensory perceptions. The pattern established by behavioural optometry's research and assumption linking bodily orientation to the physical field of vision will be followed by the mind's eye, emotions, and actions. All three theories imply the presence of such an idea as a fundamental component of their systems, even if it isn't formally stated. The database was compiled using PubMed, PubMed Central (PMC), the Cochrane library, Google scholar, and research gate. Mental Optometry provides a neurobiologically informed knowledge of mood, emotion, and thinking. Visual stimulus interpretations, enabling for therapeutic treatments to help patients recognize and rectify skewed judgments. Optometrists have an important role in patients with mental illness. Finally, we must evaluate how enhancing ocular health and visual suppleness may assist our patients improve their overall feeling of well-being.
心理验光是一个新近被认可的词,指的是心灵、大脑和感官知觉的相互作用。行为视光学的研究和假设将身体方位与物理视野联系起来,所建立的模式将被心灵之眼、情感和行动所遵循。所有这三种理论都暗示存在这样一种思想,作为其体系的基本组成部分,即使没有正式说明。该数据库通过 PubMed、PubMed Central (PMC)、Cochrane 图书馆、Google scholar 和 research gate 编辑而成。心理验光提供了有关情绪、情感和思维的神经生物学知识。对视觉刺激进行解释,帮助患者认识和纠正错误的判断,从而进行治疗。验光师在精神病患者中发挥着重要作用。最后,我们必须评估如何通过增强眼部健康和视觉柔韧性来帮助我们的患者改善他们的整体幸福感。
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引用次数: 0
期刊
Indian Journal of Clinical and Experimental Ophthalmology
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