Pub Date : 2024-01-22DOI: 10.21820/23987073.2024.1.6
Hitoshi Ishida
The process of photosynthesis holds potential to be harnessed for addressing increasing CO2 levels, as well as for finding solutions for energy shortages resulting from depleted fossil fuel reserves. Professor Hitoshi Ishida, Laboratory on Functional Metal Complexes, Kansai University, has extensive expertise in creating artificial enzymes and is interested in developing techniques to emulate photosynthesis. The plan is to create a new photocatalyst by combining photochemical CO2 reduction catalytic reactions for artificial photosynthesis with the technology of functional molecule design using ‘peptide origami’, whereby proteins fold to form higher-order structures and exhibit functions. Ishida and his team are seeking to achieve artificial photosynthesis by using ruthenium complexes as catalysts in CO2 reduction reactions that can reduce CO2 to carbon monoxide (CO) and formic acid (HCOOH), which are useful as energy sources. Ishida has created functional molecules combining metal complexes with proteins, including artificial metalloproteins ‐ a type of protein containing a metal ion ‐ using synthetic bipyridyl amino acid 5Bpy. This focused on a rare transition metal called ruthenium as the ruthenium complexes the researchers are investigating have a selectivity for carbon monoxide and formic acid reduction products that change depending on the reaction conditions. The ultimate goal of Ishida’s work is to find a solution to the problem of pollution, while addressing the need for alternatives to fossil fuels.
{"title":"The Research work of Dr. Ishida ‐ including Syntheses and Their Photocatalytic CO2 Reduction of Dinuclear Metal Complexes with Peptide Linkages project","authors":"Hitoshi Ishida","doi":"10.21820/23987073.2024.1.6","DOIUrl":"https://doi.org/10.21820/23987073.2024.1.6","url":null,"abstract":"The process of photosynthesis holds potential to be harnessed for addressing increasing CO2 levels, as well as for finding solutions for energy shortages resulting from depleted fossil fuel reserves. Professor Hitoshi Ishida, Laboratory on Functional Metal Complexes, Kansai University,\u0000 has extensive expertise in creating artificial enzymes and is interested in developing techniques to emulate photosynthesis. The plan is to create a new photocatalyst by combining photochemical CO2 reduction catalytic reactions for artificial photosynthesis with the technology of functional\u0000 molecule design using ‘peptide origami’, whereby proteins fold to form higher-order structures and exhibit functions. Ishida and his team are seeking to achieve artificial photosynthesis by using ruthenium complexes as catalysts in CO2 reduction reactions that can reduce CO2 to\u0000 carbon monoxide (CO) and formic acid (HCOOH), which are useful as energy sources. Ishida has created functional molecules combining metal complexes with proteins, including artificial metalloproteins ‐ a type of protein containing a metal ion ‐ using synthetic bipyridyl amino\u0000 acid 5Bpy. This focused on a rare transition metal called ruthenium as the ruthenium complexes the researchers are investigating have a selectivity for carbon monoxide and formic acid reduction products that change depending on the reaction conditions. The ultimate goal of Ishida’s work\u0000 is to find a solution to the problem of pollution, while addressing the need for alternatives to fossil fuels.","PeriodicalId":13517,"journal":{"name":"Impact","volume":"32 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139523493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-22DOI: 10.21820/23987073.2024.1.25
Dairoku Muramatsu
The human body already uses electric signals to transmit information to and from the brain and the rest of the body but is there potential to harness the complex interactions between living organisms and electromagnetic waves to advance scientific disciplines? Associate Professor Dairoku Muramatsu is the head of the Muramatsu Laboratory. He leads the Bioelectromagnetics Research Group, Graduate School of Information Science and Engineering Mechanical and Intelligent Systems, University of Electro-Communications, Japan. He is a specialist in bioelectromagnetic engineering that spans engineering and medicine interested in the interactions between living organisms and electromagnetic waves and how improved understanding of these interactions could lead to practical, real-world impacts. A key principle behind Muramatsuâ–™s research is that by passing a weak electric current through the human body and using the body itself as a path for electric signals, it is possible to exchange information between people and objects that come into contact with them. He is working to create innovative and highly usable technology by making full use of simulation and manufacturing. As research on human body communication, which is wireless communication that uses the human body itself as a transmission path for high-frequency signals, findings will play a key role in the spread of wearable devices. Muramatsu has already proposed bioelectromagnetic models that serve as a tool for a wide range of bioelectronics and sensor designs, including non-invasive blood glucose monitoring using bioelectromagnetic response as an evaluation criterion.
{"title":"Next-generation healthcare infrastructure based on cross-layer optimization of biosignal sensing and communication","authors":"Dairoku Muramatsu","doi":"10.21820/23987073.2024.1.25","DOIUrl":"https://doi.org/10.21820/23987073.2024.1.25","url":null,"abstract":"The human body already uses electric signals to transmit information to and from the brain and the rest of the body but is there potential to harness the complex interactions between living organisms and electromagnetic waves to advance scientific disciplines? Associate Professor Dairoku\u0000 Muramatsu is the head of the Muramatsu Laboratory. He leads the Bioelectromagnetics Research Group, Graduate School of Information Science and Engineering Mechanical and Intelligent Systems, University of Electro-Communications, Japan. He is a specialist in bioelectromagnetic engineering that\u0000 spans engineering and medicine interested in the interactions between living organisms and electromagnetic waves and how improved understanding of these interactions could lead to practical, real-world impacts. A key principle behind Muramatsuâ–™s research is that by passing\u0000 a weak electric current through the human body and using the body itself as a path for electric signals, it is possible to exchange information between people and objects that come into contact with them. He is working to create innovative and highly usable technology by making full use of\u0000 simulation and manufacturing. As research on human body communication, which is wireless communication that uses the human body itself as a transmission path for high-frequency signals, findings will play a key role in the spread of wearable devices. Muramatsu has already proposed bioelectromagnetic\u0000 models that serve as a tool for a wide range of bioelectronics and sensor designs, including non-invasive blood glucose monitoring using bioelectromagnetic response as an evaluation criterion.","PeriodicalId":13517,"journal":{"name":"Impact","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139523176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-22DOI: 10.21820/23987073.2024.1.40
Takashi Kuremoto
The guqin is an ancient Chinese stringed instrument that is an important part of Chinese culture and history. Guqin notation is a unique form of tablature known as jianzi pu that is notoriously difficult to understand. Even now, several hundreds of pieces of music remain un-played because the notation is indecipherable to modern day players. In order to access this important cultural artefact and play the guqin as it was intended in ancient times, itâ–™s essential that new methods of translating and understanding the notation are developed. Professor Takashi Kuremoto leads a team at the Department of Information Technology and Media Design, Nippon Institute of Technology, Japan, that is using AI and machine learning methods to uncover the music of the past. The researchers want to utilise deep learning to automatically recognise guqin notation. This involves collaboration with academic experts from a broad range of different fields. The goal of representing guqin notation through AI and machine learning is particularly challenging because elements of music that we recognise, such as rhythm, speed and harmony are not given in jianzi pu and the title and the words of the songs needs to be considered and arranged by musicians. The researchers created a database of single jianzi pu lines which was composed of multiple handwritten images and augmented data and adopted multiple machine learning models, such as VGG16 and SVM to increase the accuracy of classification.
{"title":"Guqing Music Recognition by Machine Learning Methods","authors":"Takashi Kuremoto","doi":"10.21820/23987073.2024.1.40","DOIUrl":"https://doi.org/10.21820/23987073.2024.1.40","url":null,"abstract":"The guqin is an ancient Chinese stringed instrument that is an important part of Chinese culture and history. Guqin notation is a unique form of tablature known as jianzi pu that is notoriously difficult to understand. Even now, several hundreds of pieces of music remain un-played because\u0000 the notation is indecipherable to modern day players. In order to access this important cultural artefact and play the guqin as it was intended in ancient times, itâ–™s essential that new methods of translating and understanding the notation are developed. Professor Takashi\u0000 Kuremoto leads a team at the Department of Information Technology and Media Design, Nippon Institute of Technology, Japan, that is using AI and machine learning methods to uncover the music of the past. The researchers want to utilise deep learning to automatically recognise guqin notation.\u0000 This involves collaboration with academic experts from a broad range of different fields. The goal of representing guqin notation through AI and machine learning is particularly challenging because elements of music that we recognise, such as rhythm, speed and harmony are not given in jianzi\u0000 pu and the title and the words of the songs needs to be considered and arranged by musicians. The researchers created a database of single jianzi pu lines which was composed of multiple handwritten images and augmented data and adopted multiple machine learning models, such as VGG16 and SVM\u0000 to increase the accuracy of classification.","PeriodicalId":13517,"journal":{"name":"Impact","volume":"25 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139523177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-22DOI: 10.21820/23987073.2024.1.34
Bo-Wen Huang, I-Cheng Li
The preservation of cultural heritage is extremely important. Expressions of culture can be passed down in different ways, including artistic expressions, objects, buildings, skills, relics and crafts. It can be difficult to preserve historical artefacts as they can fall into poor condition and finding ways to preserve or restore them is crucial to retaining a culture’s heritage. A team of researchers at the Art Conservation and Research Centre, Cheng Shiu University, Taiwan, is working on projects seeking to restore and preserve cultural relics and artefacts. The team is led by the University’s Vice Chancellor Dr Bo-Wen Huang who is interested in how innovative technologies can be harnessed to meet the Research Centre’s goals. A primary focus for the researchers is on preserving cultural and art assets located in the Asia-Pacific region of the world. Currently, the preservation and development of cultural heritage in this region is limited to the development of humanities and the social sciences but Huang believes it’s important to integrate other domains. He sees great room for improvement in the concept and implementation of cultural assets preservation and restoration in Southeast Asia. The Conservation and Research Centre takes inspiration from Singapore, Malaysia and Hong Kong as they have shown significant improvement in the field of cultural asset preservation. An important area for the team is on promoting international academic exchanges and cooperation, as well as collaborating with local art transportation companies and checking local imported and exported artworks.
{"title":"Art Conservation and Research Centre","authors":"Bo-Wen Huang, I-Cheng Li","doi":"10.21820/23987073.2024.1.34","DOIUrl":"https://doi.org/10.21820/23987073.2024.1.34","url":null,"abstract":"The preservation of cultural heritage is extremely important. Expressions of culture can be passed down in different ways, including artistic expressions, objects, buildings, skills, relics and crafts. It can be difficult to preserve historical artefacts as they can fall into poor condition\u0000 and finding ways to preserve or restore them is crucial to retaining a culture’s heritage. A team of researchers at the Art Conservation and Research Centre, Cheng Shiu University, Taiwan, is working on projects seeking to restore and preserve cultural relics and artefacts. The team\u0000 is led by the University’s Vice Chancellor Dr Bo-Wen Huang who is interested in how innovative technologies can be harnessed to meet the Research Centre’s goals. A primary focus for the researchers is on preserving cultural and art assets located in the Asia-Pacific region of the\u0000 world. Currently, the preservation and development of cultural heritage in this region is limited to the development of humanities and the social sciences but Huang believes it’s important to integrate other domains. He sees great room for improvement in the concept and implementation\u0000 of cultural assets preservation and restoration in Southeast Asia. The Conservation and Research Centre takes inspiration from Singapore, Malaysia and Hong Kong as they have shown significant improvement in the field of cultural asset preservation. An important area for the team is on promoting\u0000 international academic exchanges and cooperation, as well as collaborating with local art transportation companies and checking local imported and exported artworks.","PeriodicalId":13517,"journal":{"name":"Impact","volume":"23 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139523334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-22DOI: 10.21820/23987073.2024.1.22
Hiroaki Kubota
The elastic and plastic properties of metal can be used in various applications. Junior Associate Professor Hiroaki Kubota is working to improve manufacturing design through the application of elasto-plastic mechanics. He is particularly interested in hydroforming; a process in which steel tubes are inflated by water pressure. This can be used to produce hollow, lightweight automobile parts. Kubota previously worked in the body design and advanced development department of a car manufacturing company, learning of the importance of thickness distribution of vehicle components. It was this that inspired his current work. At the Department of Mechanical Engineering, School of Engineering, Tokai University, Japan, where Kubota is based, he is conducting research on hydroforming technology and applied research on the optimisation of plastic working using finite element analysis (FEM) and artificial intelligence (AI). Through their research on lubrication hydroforming, the team developed a forced lubrication technology that supplies high-pressure lubricant between a die and a tube during tube hydroforming, leading to even distribution and uniform wall thickness. The researchers want to expand the application of high-strength steel tubes to contribute to more lightweight and rigid cars. In their work the team confirmed that when a high-pressure lubricant was injected between the die and the steel tube, uniform wall thickness was achieved and cracking prevented. This was the very first time that forced lubrication was found to be effective in hydroforming. The team also discovered that by managing the forced lubrication, the thickness of parts can be freely controlled.
{"title":"Flexible thickness control of hydroforming by forced lubrication method in arbitrary region and time","authors":"Hiroaki Kubota","doi":"10.21820/23987073.2024.1.22","DOIUrl":"https://doi.org/10.21820/23987073.2024.1.22","url":null,"abstract":"The elastic and plastic properties of metal can be used in various applications. Junior Associate Professor Hiroaki Kubota is working to improve manufacturing design through the application of elasto-plastic mechanics. He is particularly interested in hydroforming; a process in which\u0000 steel tubes are inflated by water pressure. This can be used to produce hollow, lightweight automobile parts. Kubota previously worked in the body design and advanced development department of a car manufacturing company, learning of the importance of thickness distribution of vehicle components.\u0000 It was this that inspired his current work. At the Department of Mechanical Engineering, School of Engineering, Tokai University, Japan, where Kubota is based, he is conducting research on hydroforming technology and applied research on the optimisation of plastic working using finite element\u0000 analysis (FEM) and artificial intelligence (AI). Through their research on lubrication hydroforming, the team developed a forced lubrication technology that supplies high-pressure lubricant between a die and a tube during tube hydroforming, leading to even distribution and uniform wall thickness.\u0000 The researchers want to expand the application of high-strength steel tubes to contribute to more lightweight and rigid cars. In their work the team confirmed that when a high-pressure lubricant was injected between the die and the steel tube, uniform wall thickness was achieved and cracking\u0000 prevented. This was the very first time that forced lubrication was found to be effective in hydroforming. The team also discovered that by managing the forced lubrication, the thickness of parts can be freely controlled.","PeriodicalId":13517,"journal":{"name":"Impact","volume":"35 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139523459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.21820/23987073.2023.3.6
Sotaro Uemura
The detection and analysis of proteins is important for science and medicine and methods for sequencing and synthesising proteins have been developed to assist with this. The analysis of single molecules provides more detailed and targeted information and the development of single-molecule techniques has helped to advance molecular research. Professor Sotaro Uemura, The University of Tokyo, Japan, has over 20 years experience in this field of research, with a focus on singling out and measuring single-molecule proteins using optical tweezers, fluorescence imaging and other techniques. Labelling is a key technology that facilitates the detection of target molecules and molecular sorting by the labelling process provides numerous advantages. However, there are restrictions to this technique, leading to Uemura's involvement in utilising label-free technology to assist in the detection and measurement of single molecules. Nanopore measurement is interesting, especially in its use as a DNA sequencer but, using this method, it isn't possible to pinpoint which molecule each signal comes from. Uemura is interested in using Artificial Intelligence (AI) as an additional analysis method that can link the signals. He is working with collaborators to use machine learning to determine which molecules are producing the signals identified by nanopore measurement. Single-molecule detection, biological target samples, antibodies, ribosome fusion nanopore technology, quantitative analyses, single molecule research, molecular motors, protein synthesis, optical tweezers, fluorescence imaging technologies, biomolecular functions, DNA sequencing, machine learning, Artificial Intelligence.
{"title":"Comprehensive quantitative analysis of single-molecule proteins using ribosome fusion nanopore technology","authors":"Sotaro Uemura","doi":"10.21820/23987073.2023.3.6","DOIUrl":"https://doi.org/10.21820/23987073.2023.3.6","url":null,"abstract":"The detection and analysis of proteins is important for science and medicine and methods for sequencing and synthesising proteins have been developed to assist with this. The analysis of single molecules provides more detailed and targeted information and the development of single-molecule techniques has helped to advance molecular research. Professor Sotaro Uemura, The University of Tokyo, Japan, has over 20 years experience in this field of research, with a focus on singling out and measuring single-molecule proteins using optical tweezers, fluorescence imaging and other techniques. Labelling is a key technology that facilitates the detection of target molecules and molecular sorting by the labelling process provides numerous advantages. However, there are restrictions to this technique, leading to Uemura's involvement in utilising label-free technology to assist in the detection and measurement of single molecules. Nanopore measurement is interesting, especially in its use as a DNA sequencer but, using this method, it isn't possible to pinpoint which molecule each signal comes from. Uemura is interested in using Artificial Intelligence (AI) as an additional analysis method that can link the signals. He is working with collaborators to use machine learning to determine which molecules are producing the signals identified by nanopore measurement. Single-molecule detection, biological target samples, antibodies, ribosome fusion nanopore technology, quantitative analyses, single molecule research, molecular motors, protein synthesis, optical tweezers, fluorescence imaging technologies, biomolecular functions, DNA sequencing, machine learning, Artificial Intelligence.","PeriodicalId":13517,"journal":{"name":"Impact","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136129352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.21820/23987073.2023.3.52
Naoto Okubo
The enamel that forms the outer layer of a tooth is the hardest substance in the human body and the structure of the teeth present an opportunity for investigation. For example, Dr Naoto Okubo, who has expertise in dentistry, is interested in the raw material from which the teeth are composed ‐ dentin. Dentin has a special structure known as ` tubules´ that only exists in teeth and can be said to be a communicating porous structure. There is potential that it could be used in the development of new implantable biomaterials. Okubo's current research is exploring whether dentin can be used as a material for building bioregenerative scaffolds. He is based in the Faculty of Pharmaceutical sciences, Department of Molecular and Cellular Medicine, Hokkaido University, Japan, and is Project Leader of the Bovine Demineralized Dentin Matrix (B-DDM) projects. One of the reasons that dentin is suitable as a material for bioregenerative scaffolds is because the most important quality for bioregenerative scaffolds is that they do not interfere with the blood supply when they have been implanted. In addition, it has the strength needed to be used for bioregenerative scaffolds. In their work to use dentin and its tubule structure for the development of bioregenerative scaffolds Okubo and the team are using dentin in such a way that enables them to remove some or all the inorganic components at the same time as maintaining the tissue structure. This means the foundation of the scaffold is mainly composed of type 1 collagen, which has excellent blood permeability and high natural strength.
{"title":"Research and development of demineralised dentin-derived collagen granule bone regeneration materials using animal teeth","authors":"Naoto Okubo","doi":"10.21820/23987073.2023.3.52","DOIUrl":"https://doi.org/10.21820/23987073.2023.3.52","url":null,"abstract":"The enamel that forms the outer layer of a tooth is the hardest substance in the human body and the structure of the teeth present an opportunity for investigation. For example, Dr Naoto Okubo, who has expertise in dentistry, is interested in the raw material from which the teeth are composed ‐ dentin. Dentin has a special structure known as ` tubules´ that only exists in teeth and can be said to be a communicating porous structure. There is potential that it could be used in the development of new implantable biomaterials. Okubo's current research is exploring whether dentin can be used as a material for building bioregenerative scaffolds. He is based in the Faculty of Pharmaceutical sciences, Department of Molecular and Cellular Medicine, Hokkaido University, Japan, and is Project Leader of the Bovine Demineralized Dentin Matrix (B-DDM) projects. One of the reasons that dentin is suitable as a material for bioregenerative scaffolds is because the most important quality for bioregenerative scaffolds is that they do not interfere with the blood supply when they have been implanted. In addition, it has the strength needed to be used for bioregenerative scaffolds. In their work to use dentin and its tubule structure for the development of bioregenerative scaffolds Okubo and the team are using dentin in such a way that enables them to remove some or all the inorganic components at the same time as maintaining the tissue structure. This means the foundation of the scaffold is mainly composed of type 1 collagen, which has excellent blood permeability and high natural strength.","PeriodicalId":13517,"journal":{"name":"Impact","volume":"335 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136129206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.21820/23987073.2023.3.65
Takaya Suzuki
In organ engineering, by combining stem cells, biomaterials and bioreactors, it may be possible for scientists to produce bioengineered organs for transplantation, as well as advancing understanding of organs and diseases. Researchers from the Department of Thoracic Surgery at Tohoku University in Japan and the University of Toronto in Canada are conducting multidisciplinary international research led by thoracic surgeon Assistant Professor Takaya Suzuki (Tohoku University) to create a bioengineering lung using induced lung progenitor cells. The research revolves around designing the respiratory system and involves utilising progenitor-generating cellular reprogramming using transient gene transfection. Ultimately, the researchers are seeking to identify a way to intentionally control the developmental clock of the human body and Suzuki believes that this will be possible if the team can unveil the key mechanisms that govern this clock. Suzuki is working closely with Professor Thomas K Waddell at the University of Toronto and Toronto General Hospital. It was in Waddell's lab that the concept of partial reprogramming was conceived, alongside global leading stem cell scientist Professor Andras Nagy. Alongside his collaborators, Suzuki is seeking to transform the landscape of transplantation medicine. As partial reprogramming can be employed in various organs and cells, any kind of organ bioengineering can benefit from the research.
{"title":"Creation of bioengineered lung using induced lung progenitor cells","authors":"Takaya Suzuki","doi":"10.21820/23987073.2023.3.65","DOIUrl":"https://doi.org/10.21820/23987073.2023.3.65","url":null,"abstract":"In organ engineering, by combining stem cells, biomaterials and bioreactors, it may be possible for scientists to produce bioengineered organs for transplantation, as well as advancing understanding of organs and diseases. Researchers from the Department of Thoracic Surgery at Tohoku University in Japan and the University of Toronto in Canada are conducting multidisciplinary international research led by thoracic surgeon Assistant Professor Takaya Suzuki (Tohoku University) to create a bioengineering lung using induced lung progenitor cells. The research revolves around designing the respiratory system and involves utilising progenitor-generating cellular reprogramming using transient gene transfection. Ultimately, the researchers are seeking to identify a way to intentionally control the developmental clock of the human body and Suzuki believes that this will be possible if the team can unveil the key mechanisms that govern this clock. Suzuki is working closely with Professor Thomas K Waddell at the University of Toronto and Toronto General Hospital. It was in Waddell's lab that the concept of partial reprogramming was conceived, alongside global leading stem cell scientist Professor Andras Nagy. Alongside his collaborators, Suzuki is seeking to transform the landscape of transplantation medicine. As partial reprogramming can be employed in various organs and cells, any kind of organ bioengineering can benefit from the research.","PeriodicalId":13517,"journal":{"name":"Impact","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136129351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.21820/23987073.2023.3.34
Makiko Kasai
The important work of key LGBTQ+ groups is enhancing awareness of the challenges facing the LGBTQ+ community. Professor Makiko Kasai, Naruto University of Education, is a pioneer of LGBTQ+ focused counselling practice and counsellor training in Japan. She has written two books providing critical advice on LGBTQ+ issues to educators and counsellors and is transforming how counsellors and educators in Japan view their clients and students. Kasai is currently developing an LGBTQ+ support programme and guidelines for healthcare providers with a view to train counsellors and teachers to be LGBTQ+ sensitive and affirming and, in doing so, create a school environment where children who are struggling with sexuality and gender identity can feel safe. Kasai has developed a novel concept of inter-minority empathy that makes it possible to connect various minorities and resolve conflicts between minorities. The idea is that by improving their familiarity of individuals from sexual orientation and gender identity (SOGI) and other minority groups, people can find connections and similarities with them and better understand other people's experiences and feelings. She found that those who had experienced aggression and negative attitudes were more likely to feel empathy for other minorities who also encountered similar discrimination. Kasai has developed the minority perception scale, which is designed to measure the degree to which people perceive themselves as a minority, and the inter-minority empathy scale, which is designed to measure the degree to which people aware of their own minority status and motivate to support other minorities. Participants were surveyed to discover if they identified with any of 19 demographic categories and found a positive relationship between positive experiences as a minority and inter-minority empathy.
{"title":"Development of LGBTQ+ support program and guidelines for mental health providers","authors":"Makiko Kasai","doi":"10.21820/23987073.2023.3.34","DOIUrl":"https://doi.org/10.21820/23987073.2023.3.34","url":null,"abstract":"The important work of key LGBTQ+ groups is enhancing awareness of the challenges facing the LGBTQ+ community. Professor Makiko Kasai, Naruto University of Education, is a pioneer of LGBTQ+ focused counselling practice and counsellor training in Japan. She has written two books providing critical advice on LGBTQ+ issues to educators and counsellors and is transforming how counsellors and educators in Japan view their clients and students. Kasai is currently developing an LGBTQ+ support programme and guidelines for healthcare providers with a view to train counsellors and teachers to be LGBTQ+ sensitive and affirming and, in doing so, create a school environment where children who are struggling with sexuality and gender identity can feel safe. Kasai has developed a novel concept of inter-minority empathy that makes it possible to connect various minorities and resolve conflicts between minorities. The idea is that by improving their familiarity of individuals from sexual orientation and gender identity (SOGI) and other minority groups, people can find connections and similarities with them and better understand other people's experiences and feelings. She found that those who had experienced aggression and negative attitudes were more likely to feel empathy for other minorities who also encountered similar discrimination. Kasai has developed the minority perception scale, which is designed to measure the degree to which people perceive themselves as a minority, and the inter-minority empathy scale, which is designed to measure the degree to which people aware of their own minority status and motivate to support other minorities. Participants were surveyed to discover if they identified with any of 19 demographic categories and found a positive relationship between positive experiences as a minority and inter-minority empathy.","PeriodicalId":13517,"journal":{"name":"Impact","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136129210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.21820/23987073.2023.3.37
Naomi Ito
Japan is the first country to adopt a return policy after the all-village evacuation due to the Fukushima disaster and reporting on what's happening in such areas is important. This is the premise of the work of Naomi Ito, a Public Health Nurse with a Masters of Public Health (MPH) degree and a research assistant in the Department of Radiation Health Management at Fukushima Medical University, Japan. Her research focuses on health issues, including both the direct impacts and secondary health effects in communities where people are encouraged to return following an evacuation order. Important issues are nursing care for the elderly and the concept of ´ageing in place´. In her current study, Ito is investigating a number of cases of Fukushima nuclear accident evacuees following the 2011 nuclear accident in Fukushima and how ageing in place was impacted by relocation, including the cases of three individuals evacuated from Katsurao village who did not return to their original homes following evacuation orders. By looking at their respective health conditions, Ito gained insight into the current situation and key challenges. This research is highlighting issues associated with the provision of medical and welfare services in areas affected by the nuclear accident, with hospitals closed and the evacuation of younger people changing the social structure and impacting the future of this community. The researchers believe that a comprehensive community care system is crucial and that it is important to consider the health challenges facing evacuated residents and a required improvement to medical, welfare and transportation systems.
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