Objective: This study assessed the impact of a fixed-dose combination 5α-reductase inhibitor (5-ARI) dutasteride 0.5 mg and the α-blocker (AB) tamsulosin 0.4 mg on erectile dysfunction (ED) using The International Index of Erectile Function-5 (IIEF-5) score and Erectile Hard Score (EHS) in patients with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). Material & Methods: This was an analytical cross-sectional with consecutive sampling. We reviewed the medical records of the symptomatic BPH patients. Then we interviewed The International Prostate Symptom Score (IPSS), Quality of Life (QOL), IIEF-5, and EHS scores after administered combination therapy. The data were analyzed with SPSS IBM 21.0 using univariate and then bivariate analysis. Results: Forty (40) patients fulfilled inclusion criteria. The results showed that the frequency of patients at most in the age range of 50-59 years (40%), most of IPSS after therapy showed mild grade 45%, and moderate grade 55%. The QOL average score is 2.08, most of the patients felt pleased (35%). IIEF-5 average score after treatment is 11.6 (moderate ED) and the EHS is 2.48 (grade 2: tumescence with minimal rigidity). The Spearman test showed that there was no correlation between IPSS and IIEF-5, the score is -0.658. Then, the Spearman correlation score between BPH grade after combination treatment and ED grade is 0.739 and had a statistically significant 0.000 (p<0.001). Conclusion: This research shows that there is a correlation of the impact of tamsulosin/ dutasteride combination therapy on ED in BPH with secondary LUTS. Keywords: BPH, erectile dysfunction, tamsulosin/dutasteride combination.
目的:本研究采用国际勃起功能指数-5 (IIEF-5)评分和勃起硬评分(EHS)对良性前列腺增生(BPH)继发下尿路症状(LUTS)患者评价5α-还原酶抑制剂(5-ARI)杜他雄胺0.5 mg和α-阻滞剂(AB)坦索罗辛0.4 mg固定剂量联合用药对勃起功能障碍(ED)的影响。材料与方法:这是一个连续取样的分析横断面。我们回顾了有症状的前列腺增生患者的医疗记录。然后，我们对给予联合治疗后的国际前列腺症状评分(IPSS)、生活质量(QOL)、IIEF-5和EHS评分进行了访谈。采用SPSS IBM 21.0软件对数据进行单因素和双因素分析。结果:40例患者符合纳入标准。结果显示，50-59岁患者的发病频率最高(40%)，治疗后大部分IPSS为轻度级(45%)，中度(55%)。生活质量平均得分为2.08分，大部分患者感到满意(35%)。治疗后IIEF-5平均评分为11.6(中度ED)， EHS为2.48(2级:肿胀伴最小刚性)。Spearman检验显示IPSS与IIEF-5之间不存在相关性，得分为-0.658。联合治疗后BPH分级与ED分级的Spearman相关评分为0.739，差异有统计学意义0.000 (p<0.001)。结论:本研究表明坦索罗新/杜他雄胺联合治疗对BPH伴继发性LUTS患者ED的影响存在相关性。关键词:前列腺增生，勃起功能障碍，坦索罗新/杜他雄胺联合用药。
{"title":"CORRELATION OF THE IMPACT OF TAMSULOSIN/DUTASTERIDE COMBINATION THERAPY ON ERECTILE DYSFUNCTION (ED) IN BENIGN PROSTATIC HYPERPLASIA (BPH) IN PKU MUHAMMADIYAH GOMBONG HOSPITAL, KEBUMEN","authors":"Akhmad Miftahudin Fazri, Muhammad Irbabul Lubab","doi":"10.32421/juri.v30i1.768","DOIUrl":"https://doi.org/10.32421/juri.v30i1.768","url":null,"abstract":"Objective: This study assessed the impact of a fixed-dose combination 5α-reductase inhibitor (5-ARI) dutasteride 0.5 mg and the α-blocker (AB) tamsulosin 0.4 mg on erectile dysfunction (ED) using The International Index of Erectile Function-5 (IIEF-5) score and Erectile Hard Score (EHS) in patients with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). Material & Methods: This was an analytical cross-sectional with consecutive sampling. We reviewed the medical records of the symptomatic BPH patients. Then we interviewed The International Prostate Symptom Score (IPSS), Quality of Life (QOL), IIEF-5, and EHS scores after administered combination therapy. The data were analyzed with SPSS IBM 21.0 using univariate and then bivariate analysis. Results: Forty (40) patients fulfilled inclusion criteria. The results showed that the frequency of patients at most in the age range of 50-59 years (40%), most of IPSS after therapy showed mild grade 45%, and moderate grade 55%. The QOL average score is 2.08, most of the patients felt pleased (35%). IIEF-5 average score after treatment is 11.6 (moderate ED) and the EHS is 2.48 (grade 2: tumescence with minimal rigidity). The Spearman test showed that there was no correlation between IPSS and IIEF-5, the score is -0.658. Then, the Spearman correlation score between BPH grade after combination treatment and ED grade is 0.739 and had a statistically significant 0.000 (p<0.001). Conclusion: This research shows that there is a correlation of the impact of tamsulosin/ dutasteride combination therapy on ED in BPH with secondary LUTS. \u0000Keywords: BPH, erectile dysfunction, tamsulosin/dutasteride combination.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":"114 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82561689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aims to provide an evaluation of the outcome of patients with history of vesicovaginal fistula repair by assessing the success rate and complications that occur. Material & Methods: This study was a retrospective cohort study to describe the etiology, approach, and outcome in patients undergoing vesicovagina fistula repair. We analyzed the complication with vesicovaginal fistula type, etiology and technique used. Results: There were 10 vesicovaginal fistula patients, with mean age 33.4 ± 14.5 years. Both transabdominal and transvaginal approach were equally used. Sixty percent patient was successfully treated without complication. Forty percent patient with incontinence came with mild urinary incontinence and need further repair. Conclusion: Both transvaginal and transabdominal approach were equally effective to repair fistula with relatively low complication rate and high successful rate. Keywords: Vesicovaginal fistula, retrospective, transabdominal and transvaginal.
{"title":"OUTCOME OF VESICOVAGINAL FISTULA REPAIR AT TERTIERY HOSPITAL: COHORT STUDY","authors":"Jason Liarto, Jufriady Ismy","doi":"10.32421/juri.v30i1.774","DOIUrl":"https://doi.org/10.32421/juri.v30i1.774","url":null,"abstract":"Objective: This study aims to provide an evaluation of the outcome of patients with history of vesicovaginal fistula repair by assessing the success rate and complications that occur. Material & Methods: This study was a retrospective cohort study to describe the etiology, approach, and outcome in patients undergoing vesicovagina fistula repair. We analyzed the complication with vesicovaginal fistula type, etiology and technique used. Results: There were 10 vesicovaginal fistula patients, with mean age 33.4 ± 14.5 years. Both transabdominal and transvaginal approach were equally used. Sixty percent patient was successfully treated without complication. Forty percent patient with incontinence came with mild urinary incontinence and need further repair. Conclusion: Both transvaginal and transabdominal approach were equally effective to repair fistula with relatively low complication rate and high successful rate. \u0000Keywords: Vesicovaginal fistula, retrospective, transabdominal and transvaginal. \u0000 ","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":"146 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74030142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aims to report the possibility of non-operative management (NOM) as a Renal artery thrombosis (RAT) treatment. Case(s) Presentation: In this series, we reported 3 cases of unilateral RAT secondary to blunt abdominal trauma treated with NOM, where patient had complete bed rest, close observation, laboratory tests, and serial imaging. During a first-month follow-up, hypertension, renal abscess, persistent flank pain, or impairment of renal function were not found in the patients. However, after a one-year follow-up, an atrophic kidney appeared due to RAT in one of our cases. Discussion: RAT secondary to blunt abdominal trauma is rare. However, the management of RAT is still controversial. Renal preservation with NOM possesses reasonable success because the risk of complication does not exceed that of revascularization, and is currently considered. Conclusion: NOM is considered a treatment option in the cases of unilateral RAT with good contralateral renal function. This treatment provides a minimal number of complications. Keywords: Renal artery thrombosis, non-operative management.
{"title":"RENAL ARTERY THROMBOSIS SECONDARY TO BLUNT ABDOMINAL TRAUMA: RARE CASE SERIES","authors":"A. Syarief, F. Rizaldi","doi":"10.32421/juri.v30i1.822","DOIUrl":"https://doi.org/10.32421/juri.v30i1.822","url":null,"abstract":"Objective: This study aims to report the possibility of non-operative management (NOM) as a Renal artery thrombosis (RAT) treatment. Case(s) Presentation: In this series, we reported 3 cases of unilateral RAT secondary to blunt abdominal trauma treated with NOM, where patient had complete bed rest, close observation, laboratory tests, and serial imaging. During a first-month follow-up, hypertension, renal abscess, persistent flank pain, or impairment of renal function were not found in the patients. However, after a one-year follow-up, an atrophic kidney appeared due to RAT in one of our cases. Discussion: RAT secondary to blunt abdominal trauma is rare. However, the management of RAT is still controversial. Renal preservation with NOM possesses reasonable success because the risk of complication does not exceed that of revascularization, and is currently considered. Conclusion: NOM is considered a treatment option in the cases of unilateral RAT with good contralateral renal function. This treatment provides a minimal number of complications. \u0000Keywords: Renal artery thrombosis, non-operative management. \u0000 ","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74977633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Fam, Decky Kasman, Dilino Ryan Guntoro, Isdiyanto Septiadi
Objective: This study aims to report a case of a 51 year old male who was referred to our Department of Urology and was diagnosed with a nonfunctioning giant ACC. Case(s) Presentation: The case report describes a 51-year-old Indonesian man who presented to our department with complaints of persistent upper left abdomen discomfort, previously misdiagnosed as dyspepsia. He was diagnosed as having non-functioning adrenocortical carcinoma and underwent open adrenalectomy. Discussion: Although the patient is 51 years old and the tumor has grown to a signify cant size, no lymph node involvement or metastases was found and resection margins were found to be negative. In our patient, functional adrenal work-up results were normal. This has led us to suspect a non-functioning adrenal tumor. Metastatic work-up with CT cranial, chest, and bone survey were performed, with negative result. The biopsy result after resection confirmed the diagnosis of ACC. Conclusion: ACC is a rare aggressive tumor, malignant with poor prognosis. In our case, the non-secretory mass was diagnosed late by manifestation of mass effect symptoms in the upper left quadrant of the abdomen and was previously misdiagnosed as symptoms of dyspepsia. The functional work-up of adrenal masses helped in the determination of its non-functional status. Early diagnosis of ACC and early surgical excision helps in improving the overall survival rate of the patient. Keywords: Non-functioning, adrenocortical carcinoma (ACC), adrenalectomy, case report.
{"title":"GIANT NON-FUNCTIONING ADRENOCORTICAL CARCINOMA","authors":"I. Fam, Decky Kasman, Dilino Ryan Guntoro, Isdiyanto Septiadi","doi":"10.32421/juri.v30i1.784","DOIUrl":"https://doi.org/10.32421/juri.v30i1.784","url":null,"abstract":"Objective: This study aims to report a case of a 51 year old male who was referred to our Department of Urology and was diagnosed with a nonfunctioning giant ACC. Case(s) Presentation: The case report describes a 51-year-old Indonesian man who presented to our department with complaints of persistent upper left abdomen discomfort, previously misdiagnosed as dyspepsia. He was diagnosed as having non-functioning adrenocortical carcinoma and underwent open adrenalectomy. Discussion: Although the patient is 51 years old and the tumor has grown to a signify cant size, no lymph node involvement or metastases was found and resection margins were found to be negative. In our patient, functional adrenal work-up results were normal. This has led us to suspect a non-functioning adrenal tumor. Metastatic work-up with CT cranial, chest, and bone survey were performed, with negative result. The biopsy result after resection confirmed the diagnosis of ACC. Conclusion: ACC is a rare aggressive tumor, malignant with poor prognosis. In our case, the non-secretory mass was diagnosed late by manifestation of mass effect symptoms in the upper left quadrant of the abdomen and was previously misdiagnosed as symptoms of dyspepsia. The functional work-up of adrenal masses helped in the determination of its non-functional status. Early diagnosis of ACC and early surgical excision helps in improving the overall survival rate of the patient. \u0000Keywords: Non-functioning, adrenocortical carcinoma (ACC), adrenalectomy, case report.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88942660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Danurdoro, Tanaya Ghinorawa, P. Yuri, Didik Setyo Hariyanto, A. Rodjani, I. Wahyudi, Yonas Immanuel Hutasoit, Andre Yudha Alfanius Hutahaean
Objective: This study aims to investigate the characteristics of androgen receptors (AR), estrogen receptor 1 (ER1) and estrogen receptor 2 (ER2) expression in dartos tissue of patients with congenital hypospadias, compared to normal penis. Material & Methods: We harvested 63 dartos tissue consisting of 53 congenital hypospadias that underwent urethroplasty (20 distal and 33 proximal) and 10 normal penis that underwent circumcision as controls from September 2017 to September 2018. The expressions of AR, ER1, and ER2 were measured using Quantitative Real-Time PCR (qPCR). All data were analyzed by Prism 7, and one-way ANOVA tests were used to compare gene expressions between the groups. Results: The mean age was 68.99 (± 45.5) and 65.6 (± 25.8) months in boys with and without hypospadias, respectively. The expression of mRNA AR was decreased in proximal (6.26 ± 2.30) and distal hypospadias (6.43 ± 2.22) compared to controls (9.69 ± 1.10), which were statistically significant (p=0.0001 and p<0.0001, respectively). We found a statistically significant difference of ER1 expression compared to controls (p=0.0064). The expression of ER2 was significantly increased in distal (21.03 ± 5.00) and proximal hypospadias (25.21 ± 8.06) groups compared to controls (11.80 ± 2.49) (p<0.0001). There was no statistically significant mean difference in mRNA ER1 expression (p=0.65). Conclusion: The repressed AR and elevated ER mRNA as shown in our study may suggest that defects in those receptors’ interaction and/or balance may contribute to hypospadias and penile curvature condition. Further studies are needed to evaluate any gene-related problems in hypospadias. Keywords: Hypospadias, androgen receptor, estrogen receptor, dartos tissue.
{"title":"COMPARISON OF ANDROGEN AND ESTROGEN RECEPTORS’ EXPRESSION IN DARTOS TISSUE OF BOYS WITH AND WITHOUT HYPOSPADIAS","authors":"A. Danurdoro, Tanaya Ghinorawa, P. Yuri, Didik Setyo Hariyanto, A. Rodjani, I. Wahyudi, Yonas Immanuel Hutasoit, Andre Yudha Alfanius Hutahaean","doi":"10.32421/juri.v30i1.773","DOIUrl":"https://doi.org/10.32421/juri.v30i1.773","url":null,"abstract":"Objective: This study aims to investigate the characteristics of androgen receptors (AR), estrogen receptor 1 (ER1) and estrogen receptor 2 (ER2) expression in dartos tissue of patients with congenital hypospadias, compared to normal penis. Material & Methods: We harvested 63 dartos tissue consisting of 53 congenital hypospadias that underwent urethroplasty (20 distal and 33 proximal) and 10 normal penis that underwent circumcision as controls from September 2017 to September 2018. The expressions of AR, ER1, and ER2 were measured using Quantitative Real-Time PCR (qPCR). All data were analyzed by Prism 7, and one-way ANOVA tests were used to compare gene expressions between the groups. Results: The mean age was 68.99 (± 45.5) and 65.6 (± 25.8) months in boys with and without hypospadias, respectively. The expression of mRNA AR was decreased in proximal (6.26 ± 2.30) and distal hypospadias (6.43 ± 2.22) compared to controls (9.69 ± 1.10), which were statistically significant (p=0.0001 and p<0.0001, respectively). We found a statistically significant difference of ER1 expression compared to controls (p=0.0064). The expression of ER2 was significantly increased in distal (21.03 ± 5.00) and proximal hypospadias (25.21 ± 8.06) groups compared to controls (11.80 ± 2.49) (p<0.0001). There was no statistically significant mean difference in mRNA ER1 expression (p=0.65). Conclusion: The repressed AR and elevated ER mRNA as shown in our study may suggest that defects in those receptors’ interaction and/or balance may contribute to hypospadias and penile curvature condition. Further studies are needed to evaluate any gene-related problems in hypospadias. \u0000Keywords: Hypospadias, androgen receptor, estrogen receptor, dartos tissue. \u0000 ","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80642252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aims to present a case of Verruciform Xanthoma (VX) on penile shaft. Case(s) Presentation: A 60 years old man was admitted to our hospital with a large sized (8cm) cauliflower like tumor on his penile shaft which started to appear 2 years prior to hospital admission. The tumor was continuously getting bigger during that period. The man did not feel any other signs and symptoms. Incision biopsy sample was taken and the histopathologic result was Verruciform Xanthoma. Then the patient took excision circumcision surgery. Discussion: Penile VX is a benign, asymptomatic, warty lesion that can occur in penile shaft, glans, coronal sulcus, and preputium. Its pathological mechanism is still unclear but the most accepted theories are mucocutaneous reaction to localized trauma and chronic inflammation. Due to its atypical appearance, it can be mistaken as other lesion, even a malignant one. Histopathological examination must be done to confirm diagnosis, and to plan the right treatment. We conduct excision and circumcision to compensate a wide skin loss and achieved satisfactory result. Conclusion: Penile VX can be mistaken as a malignant lesion, thus histopathological examination must be done to avoid over radical treatment. Excision and circumcision surgery for large sized penile VX achieve satisfactory result. Keywords: Penile, verruciform xanthoma, tumor.
{"title":"AN UNUSUAL CASE OF PENILE TUMOR: GIANT SIZED VERRUCIFORM XANTHOMA OF PENIS","authors":"Aditya Yogarama, Josep Joko Hendratno","doi":"10.32421/juri.v30i1.779","DOIUrl":"https://doi.org/10.32421/juri.v30i1.779","url":null,"abstract":"Objective: This study aims to present a case of Verruciform Xanthoma (VX) on penile shaft. Case(s) Presentation: A 60 years old man was admitted to our hospital with a large sized (8cm) cauliflower like tumor on his penile shaft which started to appear 2 years prior to hospital admission. The tumor was continuously getting bigger during that period. The man did not feel any other signs and symptoms. Incision biopsy sample was taken and the histopathologic result was Verruciform Xanthoma. Then the patient took excision circumcision surgery. Discussion: Penile VX is a benign, asymptomatic, warty lesion that can occur in penile shaft, glans, coronal sulcus, and preputium. Its pathological mechanism is still unclear but the most accepted theories are mucocutaneous reaction to localized trauma and chronic inflammation. Due to its atypical appearance, it can be mistaken as other lesion, even a malignant one. Histopathological examination must be done to confirm diagnosis, and to plan the right treatment. We conduct excision and circumcision to compensate a wide skin loss and achieved satisfactory result. Conclusion: Penile VX can be mistaken as a malignant lesion, thus histopathological examination must be done to avoid over radical treatment. Excision and circumcision surgery for large sized penile VX achieve satisfactory result. \u0000Keywords: Penile, verruciform xanthoma, tumor.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82165426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harry Achsan Chaerul, Kurnia Penta Seputra, B. Daryanto
Objective: This study was undertaken to estimate the epidemiological characteristics, histological types, and subtypes of testicular neoplasm according to the WHO classification in our patient group. Material & Methods: This was a retrospective study done over a period of ten years from January 2010 - December 2020 in our institution. Histopathological slides were retrieved and reviewed for tumour. Testicular Neoplasm patients who underwent orchidectomy and chemotherapy clinical data including the patient’s age, tumor location, tumor side, pathological finding, tumor marker, chemotherapy regiment, prognosis, chemotherapy response, and side effect were observed. All the data were analyzed descriptively and using SPSS 17.0. Results: A total of 31 cases of testicular and paratesticular neoplasm were encountered in our study with a mean age of 32.516.2 years. The highest incidence was 15-35 years old (48.3). Scrotum mass was the most frequent clinical presentation (70.96%) and left side became the predominant area (52%). Most of the patients come in late stage T3 (51.61%) and N3 (67.74%) with no metastatic process (70.96). The major pathological finding was Seminoma (64.51%), Teratoma (16.12), Yolk Sac (12.9%), Embryonal, and Mixed (3.22%). AFP, B-HCG, and LDH were elevated in some Seminoma, Teratoma, and Yolk Sac groups. The most wide chemotherapy used was 4 series BEP (87.09%). Patient prognosis highest incidence were Intermediate (70.96%). Most of the patients showed complete response (67.74) of chemotherapy. Nausea, vomiting, alopecia, and mucositis were observed as chemotherapy side effect in all patients. Conclusion: Testicular neoplasm peak incidence appears in young male. Most patients come to health care service in late stage. Seminoma become the highest testicular neoplasm incidence in our study. Elevated tumor markers were found in some patients. Four cycle BEP chemotherapy regiment showed great outcome for these patients. Keywords: Epidemiological, histological, testicular neoplasm.
{"title":"CARCINOMA TESTIS PROFILE IN TERTIARY HOSPITAL","authors":"Harry Achsan Chaerul, Kurnia Penta Seputra, B. Daryanto","doi":"10.32421/juri.v30i1.816","DOIUrl":"https://doi.org/10.32421/juri.v30i1.816","url":null,"abstract":"Objective: This study was undertaken to estimate the epidemiological characteristics, histological types, and subtypes of testicular neoplasm according to the WHO classification in our patient group. Material & Methods: This was a retrospective study done over a period of ten years from January 2010 - December 2020 in our institution. Histopathological slides were retrieved and reviewed for tumour. Testicular Neoplasm patients who underwent orchidectomy and chemotherapy clinical data including the patient’s age, tumor location, tumor side, pathological finding, tumor marker, chemotherapy regiment, prognosis, chemotherapy response, and side effect were observed. All the data were analyzed descriptively and using SPSS 17.0. Results: A total of 31 cases of testicular and paratesticular neoplasm were encountered in our study with a mean age of 32.516.2 years. The highest incidence was 15-35 years old (48.3). Scrotum mass was the most frequent clinical presentation (70.96%) and left side became the predominant area (52%). Most of the patients come in late stage T3 (51.61%) and N3 (67.74%) with no metastatic process (70.96). The major pathological finding was Seminoma (64.51%), Teratoma (16.12), Yolk Sac (12.9%), Embryonal, and Mixed (3.22%). AFP, B-HCG, and LDH were elevated in some Seminoma, Teratoma, and Yolk Sac groups. The most wide chemotherapy used was 4 series BEP (87.09%). Patient prognosis highest incidence were Intermediate (70.96%). Most of the patients showed complete response (67.74) of chemotherapy. Nausea, vomiting, alopecia, and mucositis were observed as chemotherapy side effect in all patients. Conclusion: Testicular neoplasm peak incidence appears in young male. Most patients come to health care service in late stage. Seminoma become the highest testicular neoplasm incidence in our study. Elevated tumor markers were found in some patients. Four cycle BEP chemotherapy regiment showed great outcome for these patients. \u0000Keywords: Epidemiological, histological, testicular neoplasm.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91318825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andy Zulfiqqar, Ahmad Zulfan Hendri, Indrawarman Soeroharjo
Objective: This study aimed to evaluate medical resident and clerkship preferences for a variety of available Smart e-Learning options to better cope with this global pandemic. Material & Methods: This cross-sectional study using a web-based national survey was conducted between the 10th-20th of June 2020. As many as 91 of 200 (45.5% response rate) residents and clerks, who were randomly invited, responded to the survey and rated the available modalities for Smart e-Learning. Results: Generally, respondents choose morning scientific online meetings (rated 7.61/10), webinars on case discussion (7.58/10), and pre-recorded tips and tricks on surgery (7.32/10) as their favorite modalities of Smart e-Learning. Conclusion: Scientific meetings among faculty and video based learning are both equally favorite modalities of Smart e-Learning during this pandemic. Meanwhile, morning reports are the least favorite due to the majority of cases are emergency cases that lack interactive discussion. This study may provide more insights for medical faculties into how to better cope with this pandemic and continue to deliver high quality education in the ‘New Normal’ Era using Smart e-Learning options. Keywords: e-Learning, resident, clerkship, New Normal Era.
{"title":"SMART E-LEARNING OPTIONS FOR STUDENTS IN MEDICAL RESIDENCY AND CLERKSHIP DURING THE COVID-19 PANDEMIC","authors":"Andy Zulfiqqar, Ahmad Zulfan Hendri, Indrawarman Soeroharjo","doi":"10.32421/juri.v30i1.813","DOIUrl":"https://doi.org/10.32421/juri.v30i1.813","url":null,"abstract":"Objective: This study aimed to evaluate medical resident and clerkship preferences for a variety of available Smart e-Learning options to better cope with this global pandemic. Material & Methods: This cross-sectional study using a web-based national survey was conducted between the 10th-20th of June 2020. As many as 91 of 200 (45.5% response rate) residents and clerks, who were randomly invited, responded to the survey and rated the available modalities for Smart e-Learning. Results: Generally, respondents choose morning scientific online meetings (rated 7.61/10), webinars on case discussion (7.58/10), and pre-recorded tips and tricks on surgery (7.32/10) as their favorite modalities of Smart e-Learning. Conclusion: Scientific meetings among faculty and video based learning are both equally favorite modalities of Smart e-Learning during this pandemic. Meanwhile, morning reports are the least favorite due to the majority of cases are emergency cases that lack interactive discussion. This study may provide more insights for medical faculties into how to better cope with this pandemic and continue to deliver high quality education in the ‘New Normal’ Era using Smart e-Learning options. \u0000Keywords: e-Learning, resident, clerkship, New Normal Era.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77402775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This case report will discuss the experience of using percutaneous drainage as an alternative of open surgery in pararenal abscess therapy. Case(s) Presentation: 61 years old woman complained of left flank pain 6 months before with septic condition. Physical examination revealed tenderness and mass in the left flank region with leukocytosis. Abdominal Computed Tomography (CT) Scan results showed a left lower pole pararenal abscess, severe hydropyonephrosis and ureteropelvic junction stones. Percutaneous abscess drainage and percutaneous nephrostomy was performed with an 18Fr troicart using ultrasound guidance. Discussion: The pus culture showed Escherichia coli bacteria. After three days of operation and intravenous antibiotics, the patient experienced clinical improvement. Outpatient follow-up showed decreased drain production from percutaneous abscess drainage and clear yellow liquid production from percutaneous. Percutaneous nephrolithotomy was performed for the management of stone evacuation. After going through the whole procedure, there is clinical improvement of patient. Conclusion: Percutaneous drainage is an alternative option in the management of perirenal abscesses. Compared to open surgical drainage, the percutaneous technique provides a minimally invasive process, shorter length of stay and more effective costs. This procedure has also shown good clinical improvement in patients. Keywords: Minimal invasive, pararenal abscess, percutaneous drainage.
{"title":"PERCUTANEOUS DRAINAGE AS AN ALTERNATIVE OF SURGICAL MANAGEMENT IN PARARENAL ABSCESS: A CASE REPORT","authors":"Bagas Wilianto, B. Daryanto, P. Satyagraha","doi":"10.32421/juri.v30i1.831","DOIUrl":"https://doi.org/10.32421/juri.v30i1.831","url":null,"abstract":"Objective: This case report will discuss the experience of using percutaneous drainage as an alternative of open surgery in pararenal abscess therapy. Case(s) Presentation: 61 years old woman complained of left flank pain 6 months before with septic condition. Physical examination revealed tenderness and mass in the left flank region with leukocytosis. Abdominal Computed Tomography (CT) Scan results showed a left lower pole pararenal abscess, severe hydropyonephrosis and ureteropelvic junction stones. Percutaneous abscess drainage and percutaneous nephrostomy was performed with an 18Fr troicart using ultrasound guidance. Discussion: The pus culture showed Escherichia coli bacteria. After three days of operation and intravenous antibiotics, the patient experienced clinical improvement. Outpatient follow-up showed decreased drain production from percutaneous abscess drainage and clear yellow liquid production from percutaneous. Percutaneous nephrolithotomy was performed for the management of stone evacuation. After going through the whole procedure, there is clinical improvement of patient. Conclusion: Percutaneous drainage is an alternative option in the management of perirenal abscesses. Compared to open surgical drainage, the percutaneous technique provides a minimally invasive process, shorter length of stay and more effective costs. This procedure has also shown good clinical improvement in patients. \u0000Keywords: Minimal invasive, pararenal abscess, percutaneous drainage.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82578910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stevan Kristian Lionardi, Nicholas Andrian Singgih, Lutfi Bagus
Objective: To report our experience in treating a case of Testicular non-Hodgkin Lymphoma. Case(s) Presentation: A 55-year-old man came to the urology outpatient clinic with complaints of an enlarged left painless testicle that was lumpy and heavy. Urological examination found left unilateral testicle enlargement testicle, the size measured 10x7x7 cm with firm borders, solid consistency, and no tenderness. The patient then was treated with left orchiectomy. Histology and Immunohistochemical examination found non-Hodgkin B cells (CD20+) high grade, non-GCB. Discussion: In this case, the patient was treated with orchiectomy followed by a CHOP chemotherapy regimen. However, there was an unusual presentation due to the suspicion of metastases through the findings of a tender lump in the left inguinal region which was further confirmed by histological and immunohistochemical examination. Conclusion: Primary testicular lymphoma with a subtype of DLBCL (Diffuse Large B-Cell Lymphoma) is a rare disease. Orchiectomy is the initial treatment option for Testicular non-Hodgkin Lymphoma followed by combination therapy of chemotherapy to improve the prognosis. Keywords: Orchiectomy, testicular lymphoma, testicular tumors.
{"title":"PRIMARY DIFFUSE LARGE B CELL LYMPHOMA OF TESTICULAR : A CASE REPORT","authors":"Stevan Kristian Lionardi, Nicholas Andrian Singgih, Lutfi Bagus","doi":"10.32421/juri.v30i1.805","DOIUrl":"https://doi.org/10.32421/juri.v30i1.805","url":null,"abstract":"Objective: To report our experience in treating a case of Testicular non-Hodgkin Lymphoma. Case(s) Presentation: A 55-year-old man came to the urology outpatient clinic with complaints of an enlarged left painless testicle that was lumpy and heavy. Urological examination found left unilateral testicle enlargement testicle, the size measured 10x7x7 cm with firm borders, solid consistency, and no tenderness. The patient then was treated with left orchiectomy. Histology and Immunohistochemical examination found non-Hodgkin B cells (CD20+) high grade, non-GCB. Discussion: In this case, the patient was treated with orchiectomy followed by a CHOP chemotherapy regimen. However, there was an unusual presentation due to the suspicion of metastases through the findings of a tender lump in the left inguinal region which was further confirmed by histological and immunohistochemical examination. Conclusion: Primary testicular lymphoma with a subtype of DLBCL (Diffuse Large B-Cell Lymphoma) is a rare disease. Orchiectomy is the initial treatment option for Testicular non-Hodgkin Lymphoma followed by combination therapy of chemotherapy to improve the prognosis. \u0000Keywords: Orchiectomy, testicular lymphoma, testicular tumors.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78428716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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