Objective: This study aim to see the significance of R.E.N.A.L-NS in our center. Material & Methods: We retrospectively collected all the data of RCC patients that underwent partial nephrectomy (PN) in Cipto Mangunkusumo Hospital from January 2010-January 2018, with complete CT-scan examination. Patients with single kidney were excluded from our study. We evaluated intraoperative blood loss, length of operation, post operative length of stay, post operative kidney function, and complications as the perioperative parameters. Patients were categorized into 3 category based their complexity from RENAL-NS into: low (4-6), moderate (7-9), and high (10-12). Complications were based on Clavien-Dindo classification. Perioperative outcomes were analyzed based on the stratification of the patients and analyzed using ANOVA and chi-square. Results: We evaluated 25 partial nephrectomy cases which are suitable with inclusion and exclusion criteria. There were 8 (32%) low, 14 (56%) medium, and 3 (12%) high complexity cases. Median age of patients were 61 (46-71) years old, with mean tumor diameter 72.07 (+ 38.9) mm. Nine (36%) patients underwent open procedure and 16 (64%) underwent laparoscopic procedure. The laparoscopic procedure was tend to the lower complexity of R.E.N.A.L score (p=0.048). Higher complexity of R.E.N.A.L score correlated with higher blood loss (p<0.001), length of stay (p<0.001), complication rate (p<0.001), and length of operation (p=0.033). Conclusion: R.E.N.A.L-NS has a role for a selection of type of procedure and a prediction of perioperative outcome in partial nephrectomy. R.E.N.A.L-NS can be used in daily basis as it could determine the procedure and several outcomes of the partial nephrectomy procedure.
{"title":"THE ROLE OF R.E.N.A.L NEPHROMETRY SCORE TO PREDICT PERIOPERATIVE OUTCOME FOLLOWING PARTIAL NEPHRECTOMY IN A NATIONAL REFERRAL HOSPITAL","authors":"A. A. Soeroto, C. A. Mochtar, R. Umbas, A. Hamid","doi":"10.32421/juri.v29i3.800","DOIUrl":"https://doi.org/10.32421/juri.v29i3.800","url":null,"abstract":"Objective: This study aim to see the significance of R.E.N.A.L-NS in our center. Material & Methods: We retrospectively collected all the data of RCC patients that underwent partial nephrectomy (PN) in Cipto Mangunkusumo Hospital from January 2010-January 2018, with complete CT-scan examination. Patients with single kidney were excluded from our study. We evaluated intraoperative blood loss, length of operation, post operative length of stay, post operative kidney function, and complications as the perioperative parameters. Patients were categorized into 3 category based their complexity from RENAL-NS into: low (4-6), moderate (7-9), and high (10-12). Complications were based on Clavien-Dindo classification. Perioperative outcomes were analyzed based on the stratification of the patients and analyzed using ANOVA and chi-square. Results: We evaluated 25 partial nephrectomy cases which are suitable with inclusion and exclusion criteria. There were 8 (32%) low, 14 (56%) medium, and 3 (12%) high complexity cases. Median age of patients were 61 (46-71) years old, with mean tumor diameter 72.07 (+ 38.9) mm. Nine (36%) patients underwent open procedure and 16 (64%) underwent laparoscopic procedure. The laparoscopic procedure was tend to the lower complexity of R.E.N.A.L score (p=0.048). Higher complexity of R.E.N.A.L score correlated with higher blood loss (p<0.001), length of stay (p<0.001), complication rate (p<0.001), and length of operation (p=0.033). Conclusion: R.E.N.A.L-NS has a role for a selection of type of procedure and a prediction of perioperative outcome in partial nephrectomy. R.E.N.A.L-NS can be used in daily basis as it could determine the procedure and several outcomes of the partial nephrectomy procedure.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73743628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ari Baskoro, Caesar Khairul Walad, Syamsu Hudaya, Amrizal Umran
Objective: This study aims to know the effects of giant adrenal cysts and their challenges for surgeons. Case(s) Presentation: A 41 years old female was referred with a chief complaint of growing palpable mass on the left side of the abdomen since five months ago. During the past five months, the patient has also had complaints of hard narrow-caliber stools. The general conditions and vital signs have been within normal limits. Discussion: Complete resection of the tissue remains the current best treatment of choice. When available, laparoscopic adrenalectomy is the gold standard for treating giant adrenal cysts. Open adrenalectomy is an alternative when laparoscopic adrenalectomy is not available, or when there is not enough diagnostic information preoperatively. For large cysts with a size of >6cm, open surgery is the favorable treatment, because it is difficult to control the mass via the laparoscopic approach. Conclusion: The giant adrenal cyst is a rare condition that, due to its size, it could lead to moderate-severe abdominal symptoms. Localizing the origin of the cysts preoperatively poses a challenge for surgeons and diagnosticians. Intraoperative diagnostic and therapeutic with laparoscopy or open surgery is recommended for these cases.
{"title":"GIGANTIC ADRENAL CYST MIMICKING MESENTERIAL TUMOR: A CASE REPORT","authors":"Ari Baskoro, Caesar Khairul Walad, Syamsu Hudaya, Amrizal Umran","doi":"10.32421/juri.v29i3.753","DOIUrl":"https://doi.org/10.32421/juri.v29i3.753","url":null,"abstract":"Objective: This study aims to know the effects of giant adrenal cysts and their challenges for surgeons. Case(s) Presentation: A 41 years old female was referred with a chief complaint of growing palpable mass on the left side of the abdomen since five months ago. During the past five months, the patient has also had complaints of hard narrow-caliber stools. The general conditions and vital signs have been within normal limits. Discussion: Complete resection of the tissue remains the current best treatment of choice. When available, laparoscopic adrenalectomy is the gold standard for treating giant adrenal cysts. Open adrenalectomy is an alternative when laparoscopic adrenalectomy is not available, or when there is not enough diagnostic information preoperatively. For large cysts with a size of >6cm, open surgery is the favorable treatment, because it is difficult to control the mass via the laparoscopic approach. Conclusion: The giant adrenal cyst is a rare condition that, due to its size, it could lead to moderate-severe abdominal symptoms. Localizing the origin of the cysts preoperatively poses a challenge for surgeons and diagnosticians. Intraoperative diagnostic and therapeutic with laparoscopy or open surgery is recommended for these cases. \u0000 ","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80879191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aims to provide fellow physicians a better insight in diagnosing and managing similar cases. Case(s) Presentation: A 36 year old male presented to the emergency department with a chief complaint of red, painful, and progressively enlarging swelling of the left scrotal pouch since 1 week ago. The patient had a history of similar complaint and recurrent cloudy urine which were left untreated 1 year before. Based on physical examination and ultrasonography findings, the patient was diagnosed with left scrotal abscess and was treated by incisional drainage of abscess and necrotomy debridement under spinal anesthesia. Discussion: Tuberculosis infection of scrotal contents is rare and occurs in approximately 7% of the patients with tuberculosis, although tuberculosis itself is a global epidemic with more than 2 billion of the world population infected. In patients with genital tuberculosis, pulmonary and renal tuberculosis can be documented in 50% and 80-85% respectively. It is often secondary to the pre-existing tuberculosis of the urinary tract, which may be confirmed by the culture of early morning urine specimens. Conclusion: Treatment of testicular abscess is administration of appropriate antibiotics according to its causative organism accompanied by surgical drainage. Early diagnosis and prompt treatment of testicular abscess is necessary, since chronic and severe cases, as happened in this patient, usually resulted in nonviable testicular tissue and necessitate orchidectomy. This may be due to cumulative ischemia of the testicles from multiple mechanisms: inflammatory infiltration causing compression of the spermatic cord, thrombosis secondary to venous congestion and/or bacterial exotoxins.
{"title":"TUBERCULAR TESTICULAR ABSCESS: A CASE REPORT","authors":"R. Parse, A. Agil","doi":"10.32421/juri.v29i3.756","DOIUrl":"https://doi.org/10.32421/juri.v29i3.756","url":null,"abstract":"Objective: This study aims to provide fellow physicians a better insight in diagnosing and managing similar cases. Case(s) Presentation: A 36 year old male presented to the emergency department with a chief complaint of red, painful, and progressively enlarging swelling of the left scrotal pouch since 1 week ago. The patient had a history of similar complaint and recurrent cloudy urine which were left untreated 1 year before. Based on physical examination and ultrasonography findings, the patient was diagnosed with left scrotal abscess and was treated by incisional drainage of abscess and necrotomy debridement under spinal anesthesia. Discussion: Tuberculosis infection of scrotal contents is rare and occurs in approximately 7% of the patients with tuberculosis, although tuberculosis itself is a global epidemic with more than 2 billion of the world population infected. In patients with genital tuberculosis, pulmonary and renal tuberculosis can be documented in 50% and 80-85% respectively. It is often secondary to the pre-existing tuberculosis of the urinary tract, which may be confirmed by the culture of early morning urine specimens. Conclusion: Treatment of testicular abscess is administration of appropriate antibiotics according to its causative organism accompanied by surgical drainage. Early diagnosis and prompt treatment of testicular abscess is necessary, since chronic and severe cases, as happened in this patient, usually resulted in nonviable testicular tissue and necessitate orchidectomy. This may be due to cumulative ischemia of the testicles from multiple mechanisms: inflammatory infiltration causing compression of the spermatic cord, thrombosis secondary to venous congestion and/or bacterial exotoxins. \u0000 ","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85494794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aims to describe the demographic data and clinical characteristics of patient with urethral stricture in Adam Malik Hospital. Material & Methods: This research was a retrospectively designed descriptive study, with a consecutive sampling method. Data such as age, clinical symptoms, length and locations of stricture, and the type of operation conducted, were obtained from medical records from May 2013 to June 2017. All subjects had given consent that their medical records can be involved in this research. Results: 60 urethral stricture cases were found, with trauma as a major cause with a percentage of 58.3% of the cases. While the iatrogenic cause (combining post cystoscopy and post operation) contributed only 15% of the total cases. The mean age for subjects was 34.07 ± 2.044 and most of them complained about urinary retention and difficulty in initiating micturition (hesitancy). In contrast, the symptoms that were rarely revealed by subjects were weak stream and pain during micturition, with total of only 3.4% of the cases. A large part of the urethral stricture cases originated from the Bulbous part (30%) with the stricture mean length is 18.32 ± 1.944, and the part where stricture would least likely happen is the membranous and the prostatic part (8.3%). Urethrotomy (Sachse) was the favorite surgical technique used by urologists to manage urethral strictures. Conclusion: This research showed that the characteristics of patients who were diagnosed having urethral stricture in Indonesia are similar with the results from other studies conducted before. It also showed even though urethroplasty has vast advantages compared to the conventional urethrotomy (Sachse), it was still underappreciated by the surgeons.
{"title":"DEMOGRAPHIC STUDY AND THE MANAGEMENT OF URETHRAL STRICTURE IN H. ADAM MALIK GENERAL HOSPITAL","authors":"Doli Catur Utomo, F. F. Prapiska, Ramlan Nasution","doi":"10.32421/juri.v29i3.576","DOIUrl":"https://doi.org/10.32421/juri.v29i3.576","url":null,"abstract":"Objective: This study aims to describe the demographic data and clinical characteristics of patient \u0000with urethral stricture in Adam Malik Hospital. Material & Methods: This research was a retrospectively designed descriptive study, with a consecutive sampling method. Data such as age, clinical symptoms, length and locations of stricture, and the type of operation conducted, were obtained from medical records from May 2013 to June 2017. All subjects had given consent that their medical records can be involved in this research. Results: 60 urethral stricture cases were found, with trauma as a major cause with a percentage of 58.3% of the cases. While the iatrogenic cause (combining post cystoscopy and post operation) contributed only 15% of the total cases. The mean age for subjects was 34.07 ± 2.044 and most of them complained about urinary retention and difficulty in initiating micturition (hesitancy). In contrast, the symptoms that were rarely revealed by subjects were weak stream and pain during micturition, with total of only 3.4% of the cases. A large part of the urethral stricture cases originated from the Bulbous part (30%) with the stricture mean length is 18.32 ± 1.944, and the part where stricture would least likely happen is the membranous and the prostatic part (8.3%). Urethrotomy (Sachse) was the favorite surgical technique used by urologists to manage urethral strictures. Conclusion: This research showed that the characteristics of patients who were diagnosed having urethral stricture in Indonesia are similar with the results from other studies conducted before. It also showed even though urethroplasty has vast advantages compared to the conventional urethrotomy (Sachse), it was still underappreciated by the surgeons. \u0000 ","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75529538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aims to assess the safety and effectiveness of transurethral resection of prostate using preoperative and postoperative laboratory parameters. Material & Methods: This was a retrospective study of all patients treated with transurethral resection of prostate at Karawang Hospital from January – August 2018. The laboratory parameters are measured in the preoperative and postoperative period, including haemoglobin, leucocyte, and electrolyte. The outcomes of the study were the comparison of laboratory parameters before and after monopolar transurethral resection of prostate. Results: A total of 142 patients were enrolled in this retrospective study. The mean age was 68 years. Transurethral resection of prostate was performed in all patients. The mean of preoperative level of haemoglobin was higher compared to postoperative level (13.21 gr/dL vs 12.79 gr/dL; p = 0.000). The mean preoperative level of leucocyte was higher during postoperative time compared to preoperative time (13.450 vs 7503.52 p = 0.000). The sodium level was lower postoperative than preoperative ( 137.76 vs 139.39; p = 0.000 ). The potassium level was higher preoperative than in postoperative (4.12 vs 4.02, p = 0.000 ). The logistic regression was performed and shows no significant association between prostate resected weight and length of surgery compared to laboratory parameters. There was no patient who needed blood transfusion or having electrolyte derangement. Conclusion: Based on laboratory parameters, monopolar transurethral resection of prostate is safe and effective in the treatment of benign prostate hyperplasia.
目的:本研究旨在通过术前和术后实验室参数评价经尿道前列腺切除术的安全性和有效性。材料与方法:这是一项回顾性研究，纳入了2018年1月至8月在Karawang医院接受经尿道前列腺切除术的所有患者。在术前和术后测量实验室参数，包括血红蛋白、白细胞和电解质。本研究的结果是比较单极经尿道前列腺切除术前后的实验室参数。结果:本回顾性研究共纳入142例患者。平均年龄为68岁。所有患者均行经尿道前列腺切除术。术前血红蛋白水平的平均值高于术后水平(13.21 gr/dL vs 12.79 gr/dL;P = 0.000)。术后平均白细胞水平高于术前(13.450 vs 7503.52 p = 0.000)。术后钠水平低于术前(137.76 vs 139.39;P = 0.000)。钾水平术前高于术后(4.12 vs 4.02, p = 0.000)。进行了逻辑回归，与实验室参数相比，前列腺切除的重量和手术长度之间没有显着关联。没有患者需要输血或电解质紊乱。结论:基于实验室参数，经尿道单极前列腺切除术治疗良性前列腺增生安全有效。
{"title":"SAFETY AND EFFICACY OF MONOPOLAR TRANSURETHRAL RESECTION OF PROSTATE IN LABORATORY PARAMETERS","authors":"P. Putra, Rajasa H., Achmad Rizky Herda","doi":"10.32421/juri.v29i3.585","DOIUrl":"https://doi.org/10.32421/juri.v29i3.585","url":null,"abstract":"Objective: This study aims to assess the safety and effectiveness of transurethral resection of prostate using preoperative and postoperative laboratory parameters. Material & Methods: This was a retrospective study of all patients treated with transurethral resection of prostate at Karawang Hospital from January – August 2018. The laboratory parameters are measured in the preoperative and postoperative period, including haemoglobin, leucocyte, and electrolyte. The outcomes of the study were the comparison of laboratory parameters before and after monopolar transurethral resection of prostate. Results: A total of 142 patients were enrolled in this retrospective study. The mean age was 68 years. Transurethral resection of prostate was performed in all patients. The mean of preoperative level of haemoglobin was higher compared to postoperative level (13.21 gr/dL vs 12.79 gr/dL; p = 0.000). The mean preoperative level of leucocyte was higher during postoperative time compared to preoperative time (13.450 vs 7503.52 p = 0.000). The sodium level was lower postoperative than preoperative ( 137.76 vs 139.39; p = 0.000 ). The potassium level was higher preoperative than in postoperative (4.12 vs 4.02, p = 0.000 ). The logistic regression was performed and shows no significant association between prostate resected weight and length of surgery compared to laboratory parameters. There was no patient who needed blood transfusion or having electrolyte derangement. Conclusion: Based on laboratory parameters, monopolar transurethral resection of prostate is safe and effective in the treatment of benign prostate hyperplasia.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74796560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rakha Sulthan Salim, Rabinda Fitriana Tuasikal, Mo Tualeka
Objective: To present a rare case of a giant bladder stone. Case(s) Presentation: We report a 20-year-old fisherman, with excessive exposure to sunlight, poor fluid intake, and unhealthy lifestyle, who came to the hospital clinic with a 2-year-history of progressing dysuria, frequency, and hematuria. Investigations revealed a giant bladder stone without bladder outlet obstruction. Open cystolithotomy was performed and a giant stone with 13.2x8x8.3 cm in size was extracted without adhesion to the bladder wall. Discussion: A Giant bladder stone is a rare disease and fewer than 100 cases have been reported globally. Patients commonly are accompanied by multifactorial conditions and have a wide range of presentations. Conclusion: This case presents a giant bladder stone without bladder outlet obstruction in a young adult, it is considered that the stone rose due to other significant factors that followed the patient.
{"title":"A GIANT BLADDER STONE IN A YOUNG FISHERMAN FROM MOLUCCAS: A CASE REPORT","authors":"Rakha Sulthan Salim, Rabinda Fitriana Tuasikal, Mo Tualeka","doi":"10.32421/juri.v29i3.770","DOIUrl":"https://doi.org/10.32421/juri.v29i3.770","url":null,"abstract":"Objective: To present a rare case of a giant bladder stone. Case(s) Presentation: We report a 20-year-old fisherman, with excessive exposure to sunlight, poor fluid intake, and unhealthy lifestyle, who came to the hospital clinic with a 2-year-history of progressing dysuria, frequency, and hematuria. Investigations revealed a giant bladder stone without bladder outlet obstruction. Open cystolithotomy was performed and a giant stone with 13.2x8x8.3 cm in size was extracted without adhesion to the bladder wall. Discussion: A Giant bladder stone is a rare disease and fewer than 100 cases have been reported globally. Patients commonly are accompanied by multifactorial conditions and have a wide range of presentations. Conclusion: This case presents a giant bladder stone without bladder outlet obstruction in a young adult, it is considered that the stone rose due to other significant factors that followed the patient.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78839296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dio Mafazi Fabrianta, Kurnia Penta Seputra, B. Daryanto
Objective: The purpose of this study was to determine the correlation of testicular tumor markers on the success of chemotherapy in my institution. Material & Methods: This research is a retrospective study single center using the medical record database at the span of the research period. The patient with testicular carcinoma who underwent complete chemotherapy between 2017 until 2022 was included. The data collected and analyzed by descriptive data and analytical correlation using SPSS Ver. 25. The comparation test using T-test and Anova. Results: A total of 31 testicular cancer patients were enrolled in the study. Fifteen patients were seminoma and 16 patients were non-seminoma. The mean age of patient at presentation of seminoma and non seminoma were 38.3 ± 17.03 and 30.74 ± 13.01. Most patients presented a karnofsky score about 79 ± 15. There was a negative correlation (r=-0.492) with a significant correlation between the types of testicular carcinoma cases and the response to chemotherapy (p=0.027). There was a significant difference in cases of seminoma and non-seminoma to the success of the chemotherapy response (p=0.024). There was a positive correlation between serum β-HCG, AFP, LDH with serial chemotherapy result with a no significant correlation (p=0.879; p=0.242; and p=0.277). Conclusion: Most types of the testicular carcinoma responses to chemotherapy. Patients with seminoma pathology have better response to chemotherapy compared to non-seminoma.
{"title":"CHARACTERISTIC CHEMOTHERAPY RESPONSE OF TESTICULAR CANCER PATIENTS IN TERTIARY HOSPITAL","authors":"Dio Mafazi Fabrianta, Kurnia Penta Seputra, B. Daryanto","doi":"10.32421/juri.v29i3.823","DOIUrl":"https://doi.org/10.32421/juri.v29i3.823","url":null,"abstract":"Objective: The purpose of this study was to determine the correlation of testicular tumor markers on the success of chemotherapy in my institution. Material & Methods: This research is a retrospective study single center using the medical record database at the span of the research period. The patient with testicular carcinoma who underwent complete chemotherapy between 2017 until 2022 was included. The data collected and analyzed by descriptive data and analytical correlation using SPSS Ver. 25. The comparation test using T-test and Anova. Results: A total of 31 testicular cancer patients were enrolled in the study. Fifteen patients were seminoma and 16 patients were non-seminoma. The mean age of patient at presentation of seminoma and non seminoma were 38.3 ± 17.03 and 30.74 ± 13.01. Most patients presented a karnofsky score about 79 ± 15. There was a negative correlation (r=-0.492) with a significant correlation between the types of testicular carcinoma cases and the response to chemotherapy (p=0.027). There was a significant difference in cases of seminoma and non-seminoma to the success of the chemotherapy response (p=0.024). There was a positive correlation between serum β-HCG, AFP, LDH with serial chemotherapy result with a no significant correlation (p=0.879; p=0.242; and p=0.277). Conclusion: Most types of the testicular carcinoma responses to chemotherapy. Patients with seminoma pathology have better response to chemotherapy compared to non-seminoma.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85378322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aims to describe the risk factors of bladder cancer patients in Arifin Achmad Regional General Hospital, Riau Province, Indonesia. Material & Methods: We reviewed the medical records of bladder cancer patients managed in Arifin Achmad Regional General Hospital from January 2013 - December 2017. The data collected were sex, age, histopathology types, staging, smoking history, occupation, ethnic/tribes, and city/district origine. Statistical analysis of univariate was used. Approval on the study was obtained from the Ethical Review Board for Medicine and Health Research, Medical Faculty, University of Riau. Results: There were 101 bladder cancer patients consisting of 83.2% patients with transitional cell carcinoma and 65.3% with advanced stage. The result showed the most common (82.2%) patients were males and 35.6% of patients were in age 51-60 year old group, with the youngest was in 9 year old group and the oldest is 85 years. The most common risk factors of bladder cancer patient were farmers in 29.7% and the non-smoking patients were in 52.5%, Malay ethnic in 30.7% and Pekanbaru origin in 30.7% of patients. Conclusion: Bladder cancer risk factors in Arifin Achmad Regional General Hospital were males, farmers, Malay ethnic, and Pekanbaru origin.
{"title":"RISK FACTORS OF BLADDER CANCER PATIENTS IN ARIFIN ACHMAD REGIONAL GENERAL HOSPITAL, RIAU PROVINCE, INDONESIA","authors":"Zuhirman Zamzami","doi":"10.32421/juri.v29i3.560","DOIUrl":"https://doi.org/10.32421/juri.v29i3.560","url":null,"abstract":"Objective: This study aims to describe the risk factors of bladder cancer patients in Arifin Achmad Regional General Hospital, Riau Province, Indonesia. Material & Methods: We reviewed the medical records of bladder cancer patients managed in Arifin Achmad Regional General Hospital from January 2013 - December 2017. The data collected were sex, age, histopathology types, staging, smoking history, occupation, ethnic/tribes, and city/district origine. Statistical analysis of univariate was used. Approval on the study was obtained from the Ethical Review Board for Medicine and Health Research, Medical Faculty, University of Riau. Results: There were 101 bladder cancer patients consisting of 83.2% patients with transitional cell carcinoma and 65.3% with advanced stage. The result showed the most common (82.2%) patients were males and 35.6% of patients were in age 51-60 year old group, with the youngest was in 9 year old group and the oldest is 85 years. The most common risk factors of bladder cancer patient were farmers in 29.7% and the non-smoking patients were in 52.5%, Malay ethnic in 30.7% and Pekanbaru origin in 30.7% of patients. Conclusion: Bladder cancer risk factors in Arifin Achmad Regional General Hospital were males, farmers, Malay ethnic, and Pekanbaru origin.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90649415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aims to study whether hypospadias repair in primary cases can be done in a single stage. We present patients’ perspective and their outcomes in 268 primary hypospadias cases among which around 90% of patients (n=240) had their hypospadias surgery after recommended age of repair (18 months). All primary cases were managed in a single stage. Material & Methods: From January 2010 – December 2019, 377 patients were included and outcomes were documented. Patients with prior hypospadias with complications (n=48), chordee without hypospadias (n=16), isolated penile torsion (n=12), and 33 patients who were lost to follow-up were excluded. The age at surgery, location of the meatus, chordee, associated anomalies, techniques used for correction, postoperative complications with overall success rate and patient related outcomes were evaluated. Results: After orthoplasty, distal hypospadias was seen in 59% (n=158), middle in 22.8 % (n=61) & proximal in 13.1% (n=35) patients. Fourteen patients (5.2%) had penoscrotal transposition. Chordee was present in 71.2% (n=192) cases. Urethral closure was done using TIP alone in 18 cases, TIP, and spongioplasty (n=233). The success rate of one-stage surgery was 73.5% in our series which correlated with PRO with high significance. Conclusion: The rate of complications increased with the length of urethral tube reconstruction. Hypospadias fistula was the most common, followed by glanular dehiscence. The use of the TIP in primary repairs, spongioplasty & additional buffering layers reduced the complication rates. Patients can have acceptable residual chordee and torsion and their surgical results correlated well with patient related outcomes(PRO).
{"title":"SINGLE STAGE HYPOSPADIAS REPAIR IN PRIMARY CASES AND THEIR PATIENT RELATED OUTCOMES – TERTIARY CARE CENTER EXPERIENCE","authors":"Mukesh Chandra Arya, Ram Naresh Daga, Ajay Gandhi, Ankur Singhal, Yogendra Shyoran, Medhanshu Kumar","doi":"10.32421/juri.v29i3.801","DOIUrl":"https://doi.org/10.32421/juri.v29i3.801","url":null,"abstract":"Objective: This study aims to study whether hypospadias repair in primary cases can be done in a single stage. We present patients’ perspective and their outcomes in 268 primary hypospadias cases among which around 90% of patients (n=240) had their hypospadias surgery after recommended age of repair (18 months). All primary cases were managed in a single stage. Material & Methods: From January 2010 – December 2019, 377 patients were included and outcomes were documented. Patients with prior hypospadias with complications (n=48), chordee without hypospadias (n=16), isolated penile torsion (n=12), and 33 patients who were lost to follow-up were excluded. The age at surgery, location of the meatus, chordee, associated anomalies, techniques used for correction, postoperative complications with overall success rate and patient related outcomes were evaluated. Results: After orthoplasty, distal hypospadias was seen in 59% (n=158), middle in 22.8 % (n=61) & proximal in 13.1% (n=35) patients. Fourteen patients (5.2%) had penoscrotal transposition. Chordee was present in 71.2% (n=192) cases. Urethral closure was done using TIP alone in 18 cases, TIP, and spongioplasty (n=233). The success rate of one-stage surgery was 73.5% in our series which correlated with PRO with high significance. Conclusion: The rate of complications increased with the length of urethral tube reconstruction. Hypospadias fistula was the most common, followed by glanular dehiscence. The use of the TIP in primary repairs, spongioplasty & additional buffering layers reduced the complication rates. Patients can have acceptable residual chordee and torsion and their surgical results correlated well with patient related outcomes(PRO).","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78406894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study aims to test the efficacy of Nigella Sativa plant as an inhibitor of calcium oxalate crystallization. Material & Methods: Nigella Sativa alcohol extract was made by maceration of 100 grams Nigella seeds which were dried and powdered for 72 hours and then filtered, so as to produce 100 percent Nigella alcohol extract. Then make dilutions of 10 and 50 percent. The precipitation of calcium oxalate at 37 0C and pH 5.7 was studied by measurement of turbidity at 620 nm with and without inhibitor which is Nigella Sativa. Results: Tmax, the slope of nucleation (SN) and slope of aggregation (SA) was measured with control and with inhibitor. With increasing concentration of inhibitor, Tmax progressively increased, whereas SN and SA decreased. The nucleation percentage inhibition ratio was 86.0% and inhibition of crystal aggregation took place by 66.6% with 100% extract. Crystallization was inhibited (growth and aggregation) in a concentration dependent manner. Conclusion: Nigella Sativa is strong inhibitor of calcium oxalate crystallization. However, comprehensive work is needed to establish the results.
{"title":"IN VITRO STUDY ON NIGELLA SATIVA AS INHIBITOR OF CALCIUM OXALATE CRYSTALLIZATION","authors":"Shafīq Aḥmad, M. Shad, T. Ansari","doi":"10.32421/juri.v29i3.565","DOIUrl":"https://doi.org/10.32421/juri.v29i3.565","url":null,"abstract":"Objective: This study aims to test the efficacy of Nigella Sativa plant as an inhibitor of calcium oxalate crystallization. Material & Methods: Nigella Sativa alcohol extract was made by maceration of 100 grams Nigella seeds which were dried and powdered for 72 hours and then filtered, so as to produce 100 percent Nigella alcohol extract. Then make dilutions of 10 and 50 percent. The precipitation of calcium oxalate at 37 0C and pH 5.7 was studied by measurement of turbidity at 620 nm with and without inhibitor which is Nigella Sativa. Results: Tmax, the slope of nucleation (SN) and slope of aggregation (SA) was measured with control and with inhibitor. With increasing concentration of inhibitor, Tmax progressively increased, whereas SN and SA decreased. The nucleation percentage inhibition ratio was 86.0% and inhibition of crystal aggregation took place by 66.6% with 100% extract. Crystallization was inhibited (growth and aggregation) in a concentration dependent manner. Conclusion: Nigella Sativa is strong inhibitor of calcium oxalate crystallization. However, comprehensive work is needed to establish the results.","PeriodicalId":13565,"journal":{"name":"Indonesian Journal of Urology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85670443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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