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Korean Red Ginseng: Benefits Versus Precautions 高丽红参:益处与预防
Pub Date : 2018-12-05 DOI: 10.26689/ITPS.V1I1.417
E. Makky
Over the years, Korean red ginseng (RG), scientifically known as Panax ginseng, has been used to treat several diseases. It is a prominent and ancient medicinal herb in the Orient. Ginseng ginsenoside is the major component of RG which has been presumed to be responsible for the health benefits of RG. Many studies on P. ginseng have until now concentrated on the mechanism of action of the individual components of RG. However, despite the numerous research on the molecular basis of P. ginseng activities, it is still confusing how several active components can simultaneously interact with several targets to give the diverse effects in different diseases. This overview covered the positive and negative effects of using the Korean RG; it also outlined the major chemical components of the Korean RG.
多年来,韩国红参(RG),科学上被称为人参,已被用于治疗几种疾病。它是东方著名的古老草药。人参皂苷是RG的主要成分,被认为是RG对健康有益的原因。到目前为止,对人参的研究主要集中在RG各成分的作用机制上。然而,尽管对人参活性的分子基础进行了大量的研究,但几种活性成分如何同时与几种靶点相互作用,从而在不同的疾病中产生不同的作用,仍然令人困惑。这个概述涵盖了使用韩国RG的积极和消极影响;它还概述了韩国RG的主要化学成分。
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引用次数: 1
Supplementation of Carrot Incorporated Paneer Attenuates Diabetes through its Antioxidant Potential in Streptozotocin-Nicotinamide-Induced Diabetic Rats 在链脲佐菌素-烟酰胺诱导的糖尿病大鼠中,补充胡萝卜加干酪可通过其抗氧化潜力减轻糖尿病
Pub Date : 2018-12-05 DOI: 10.26689/ITPS.V1I1.440
P. Nivedha, V. Uddandrao, G. Saravanan, P. Brahmanaidu, S. Vadivukkarasi
Background: The ideal medications for diabetes mellitus (DM) should have less or no adverse effects, thus screening on the antidiabetic activities of plant-based products is in urgent need. Paneer is the fundamental nutritious and complete native dairy products, and natural products incorporated paneer has greatly increased its therapeutic potential.Objective: The current study was undertaken to explore the effects of carrot incorporated paneer (CIP) on blood glucose, body weight, insulin, and enzymatic antioxidants such as superoxide dismutase, catalase, glutathione (GSH) peroxidase, and reduced GSH in streptozotocin (STZ) and nicotinamide (NAD)-induced diabetes in rats.Materials and Methods: Diabetic rats were orally supplemented with CIP (200 mg/kg body weight/day) for 1 month and the effects were compared with gliclazide (5 mg/kg body weight/day).Results: Supplementation of CIP or gliclazide was resulted in noteworthy diminish in the levels of blood glucose and increase in body weight and insulin levels. STZ-NAD administration caused the diminution in enzymatic antioxidant activities in diabetic rats and supplementation with CIP predominantly enhanced the levels of antioxidant enzymes in diabetic rats when contrasted to diabetic group.Conclusion: Hence, the results suggested that CIP has the potential antioxidant capability and may be believed as an efficient curative constituent for the management of DM.
背景:理想的治疗糖尿病的药物应该是不良反应少或无不良反应,因此筛选植物性产品的抗糖尿病活性是迫切需要的。印度奶酪是基本的营养和完整的本地乳制品,天然产品中加入了印度奶酪,大大增加了其治疗潜力。目的:探讨胡萝卜掺入奶酪(CIP)对链脲霉素(STZ)和烟酰胺(NAD)诱导的糖尿病大鼠血糖、体重、胰岛素以及酶抗氧化剂如超氧化物歧化酶、过氧化氢酶、谷胱甘肽(GSH)过氧化物酶和降低谷胱甘肽的影响。材料与方法:将糖尿病大鼠口服CIP (200 mg/kg体重/天)1个月,并与格列齐特(5 mg/kg体重/天)进行比较。结果:补充CIP或格列齐特可显著降低血糖水平,增加体重和胰岛素水平。与糖尿病组相比,添加STZ-NAD导致糖尿病大鼠体内酶抗氧化活性降低,而添加CIP显著提高了糖尿病大鼠体内的抗氧化酶水平。结论:CIP具有潜在的抗氧化能力,可能是治疗糖尿病的有效成分。
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引用次数: 0
Identification and Documentation of Potential Drug-Drug Interactions in Inpatients at a Tertiary Care Center 一家三级医疗中心住院病人潜在药物相互作用的识别和记录
Pub Date : 2018-12-05 DOI: 10.26689/itps.v1i1.438
A. Divya, V. Bakshi, B. Narender
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引用次数: 0
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INNOSC Theranostics and Pharmacological Sciences
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